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Systems and methods for programmatically generating anamorphic images for presentation and 3d viewing in a physical gaming and entertainment suite
Systems and methods for programmatically generating anamorphic images for presentation in a physical gaming suite (e.g., anamorphic images that are viewable without requiring any external wearable device) are disclosed herein. An example method includes: monitoring, using data received from one or more sensors, viewing characteristics associated with one or more game participants in the physical gaming suite.

Aryl ureas with angiogenisis inhibiting activity
This invention relates to methods of using aryl ureas to treat diseases mediated by the vegf induced signal transduction pathway characterized by abnormal angiogenesis or hyperpermeability processes.. .


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Most effective process for base-free preparation of ketone intermediates usable for manufacture of nebivolol
Comprising the steps of: activation of a carboxylic acid by using a peptide coupling agent, coupling of the activated carboxylic acid with a malonic acid derivative providing a β-ketoester precursor and converting the β-ketoester precursor to the ketone of the general formula 1.. .

Heterocyclic compounds useful in the treatment of disease
Heterocyclic compounds are described that are lysophosphatidic acid receptor ligands that are useful in the treatment of lysophosphatidic acid receptor-dependent diseases and conditions, including but not limited to diseases involving fibrosis, such as fibrosis of the heart, kidney, liver and lung, and scleroderma; inflammatory diseases such as diabetic nephropathy and nonalcoholic steatohepatitis (nash); ocular diseases such as diseases involving retinal degeneration; nerve diseases such as pruritus and pain.. .

N-(4-hydroxy-4-methyl-cyclohexyl)-4-phenyl-benzenesulfonamide and n-(4-hydroxy-4-methyl-cyclohexyl)-4-(2-pyridyl)-benzenesulfonamide compounds and their therapeutic use
The present invention pertains generally to the field of therapeutic compounds. More specifically the present invention pertains to certain substituted n-(4-hydroxy-4-methyl-cyclohexyl)-4-phenyl-benzenesulfonamide and n-(4-hydroxy-4-methyl-cyclohexyl)-4-(2-pyridyl)benzenesulfonamide compounds (collectively referred to herein as hmc compounds) that are useful, for example, in the treatment of disorders (e.g., diseases) including, inflammation and/or joint destruction and/or bone loss; disorders mediated by excessive and/or inappropriate and/or prolonged activation of the immune system; inflammatory and autoimmune disorders, for example, rheumatoid arthritis; psoriasis; psoriatic arthritis; chronic obstructive pulmonary disease (copd); asthma; atherosclerosis; inflammatory bowel disease; ankylosing spondylitis; multiple sclerosis; systemic lupus erythematosus; sjogren's syndrome; a disorder associated with bone loss, such as bone loss associated with excessive osteoclast activity in rheumatoid arthritis, osteoporosis, cancer-associated bone disease, or paget's disease; cancer, such as a haematological malignancy, such as multiple myeloma, leukemia, or lymphoma, or a solid tumour cancer, such as bladder cancer, breast cancer (female and/or male), colon cancer, renal cell carcinoma, kidney cancer, lung cancer, pancreatic cancer, gastric cancer, prostate cancer, brain cancer, skin cancer, thyroid cancer, basal cell ameloblastoma, or melanoma; a disorder associated with fibrosis, such as systemic sclerosis or scleroderma; or a rare vasculitide, such as behçet's disease.

Method for controlling the process for making isocyanates
The invention relates to a method for preparing an aromatic polyisocyanate in an isocyanate plant comprising a reaction section for a phosgenation reaction, wherein a primary aromatic amine is reacted with phosgene compounds in a reaction section to obtain an isocyanate comprising reaction product and wherein co2 concentration in the gases coming from the reaction section is measured and analyzed, and wherein the conditions in the phosgenation reaction are adjusted in case the co2 concentration in the gases coming from the reaction section is higher than a background co2 concentration.. .

Methods and compositions for improving plant traits

Disclosed herein are methods of increasing nitrogen fixation in a non-leguminous plant. The methods can comprise exposing the plant to a plurality of bacteria.

Methods and compositions for improving plant traits

Disclosed herein are methods of increasing nitrogen fixation in a non-leguminous plant. The methods can comprise exposing the plant to a plurality of bacteria.

Sewage treatment system

A septic system, including a septic tank and a pipe positioned within the septic tank, is provided. The pipe receives sewage and provides a flooded, anaerobic environment for sewage passing therethrough.

Sequencing batch reactor for sewage treatment and sewage treatment system comprising same

Disclosed is a sequencing batch reactor (sbr) for sewage treatment. The sbr is applicable to an energy-producing sewage treatment system.

Waste treatment system

A waste treatment system may include a liquid separator for removing water from solid waste, a mixing tank connected to the liquid separator for mixing the solid waste with an oxidizing agent, a heat exchanger connected to the mixing tank for collecting heat generated by an exothermic reaction caused by mixing the oxidizing agent with the solid waste, and a sanitizer connected to the liquid separator to sanitize the water removed from the solid waste. A waste treatment method may involve separating water from solid waste in a liquid separator, mixing the solid waste from the liquid separator with an oxidizing agent in a mixing tank connected to the liquid separator to cause an exothermic reaction, collecting heat from the exothermic reaction in a heat exchanger coupled with the mixing tank, and sanitizing the water from the liquid separator in a sanitizer..

Electroflotation apparatus having an outlet pipe with a low turbulence orifice

An electroflotation apparatus for removing impurities from waste water is disclosed. The apparatus comprises an electrolytic cell for treating the waste water and generating a flock containing the impurities as well as an outlet pipe having a linear central axis located co-axially with the electrolytic cell for passing the water and flock from the electrolytic cell to a separation area.

Vanadium recovery method

A vanadium recovery approach utilizes oil fly ash (ofa), in contrast to coal fly ash, for separation and recovery of vanadium. Ofa is first carbon burned to reduce the volume for recycling, and also to provide a fuel for other industrial processes.

Cold plasma ozone generator

The present invention provides a cold plasma ozone generator, comprising: an inlet gas port; at least one in-electrode, said in-electrode having a plurality of holes substantially at a perimeter of the same; said plurality of perimeter holes are in fluid communication with said inlet gas port, said plurality of perimeter holes configured to allow said dry gas to pass therethrough; at least one out-electrode, said out-electrode having at least one hole at the center of the same, said at least one hole configured to allow gas to pass therethrough; said in-electrode and said out-electrode configured to maintain said high voltage ac therebetween; at least one spacer between said in-electrode and said out-electrode, said spacer configured to maintain a constant-width gap between said in-electrode and said out-electrode; an outlet port.. .

Method of generating hydrogen-containing liquid

A method is provided, comprising: preparing a hydrogen generating agent (14) that reacts with water to generate hydrogen gas, a first container (11) that encloses a liquid (16) applicable to a living organism and has hydrogen gas permeability, and a second container (12) that has hydrogen gas permeability equal to or lower than the hydrogen permeability of the first container; storing the first container and the hydrogen generating agent in the second container and sealing the second container with no water except moisture in air; maintaining the second container storing the first container and the hydrogen generating agent in a frozen state from when the second container is sealed until when the liquid is used; upon use of the liquid, placing the second container storing the first container and the hydrogen generating agent in an unfreezing atmosphere so that the hydrogen generating agent reacts with water in the second container to generate hydrogen gas in the second container, the water in the second container including water vapor resulting from vaporization of water contained in the liquid stored in the first container and permeation of the water vapor through the first container into the second container and/or the moisture in air in the second container; and allowing the hydrogen gas generated in the second container to pass through the first container so that hydrogen molecules are contained in the liquid stored in the first container.. .

System and process for generating hydrogen

Also the present invention refers to a chemical process for generating hydrogen using alkali metals, alkaline earth metals, hydrides of alkali metals or hydrides of earth alkali metals to obtain primary by products from water. Then the primary by products reacts with a metal reactant to obtain additional hydrogen..

Regenerative power capture system for endless track escalators and moving walkways

Power is recovered from an escalator or a moving walkway as the step orbits an endless track on rollers. A generator is connected to a roller orbiting the track.

Device for adjusting the position of an elevator system, and elevator system

A device for adjusting the position of an elevator system, having position measuring means (14) that can be assigned to an elevator car (2) which is movable in an elevator shaft (6), which are designed for generating position data corresponding to a current shaft position of the elevator car, and position control means (34) which interact with the position measuring means (14) and which are paired with configuration means (16) that can be actuated manually and/or by means of data input means, in such a way that as a response to a manual actuation and/or actuation of the data input means, a plurality of car stopping positions that are distributed along the elevator shaft can be adjusted and stored, wherein a mobile data processing unit (26) which is wirelessly linked to the configuration means and which has a display unit (28) is paired with the configuration means (16), such that position data corresponding to the plurality of car stopping positions can be displayed together on the display, and the mobile data processing unit has manually actuatable operating means (28) for changing at least one of the items of position data and for transmitting the changed item of position data to the configuration means.. .

Apparatus and making inflated articles

A sealing device generally includes a rotatable support cylinder having an outer, circumferential surface and a heating element disposed about such surface and secured thereto such that the heating element rotates therewith. The heating element is coiled about the outer surface of the cylinder in the form of an overlapping helical pattern.

Semiregular polyhedron box and assembly

A semiregular polyhedron box and method of assembly provides a rectangular cross-section, ten faces, twenty-four edges, and sixteen vertices. The box is plastic corrugated and has two rectangular sidewalls, two square sidewalls, and four corner sidewalls.

Automation for plastic disc

An apparatus for reinforcing stapling connections created by an elastic stapling apparatus with a plurality of individual reinforcing elements. The apparatus constructs and deploys the plurality of individual reinforcing elements simultaneously with the elastic stapling apparatus generating a plurality of plastic fasteners.

Packaging machine having an improved adjustment function

An apparatus comprising a packaging machine, which comprises a control unit having a process parameter generator designed to determine specific process parameters for a production process of the packaging machine. The control unit of the packaging machine also comprises a recipe generator for an adjustment process of the packaging machine preceding the production process or can be connected to a recipe generator of the apparatus, which generator is designed as a separate unit.

Methods and apparatus to monitor health information of a turbine engine

Methods, apparatus, and articles of manufacture to monitor health information of a turbine engine are disclosed. An example apparatus includes a parameter calculator to determine a baseline value of a set of health parameters for a turbine engine of a vehicle based on a first set of sensor measurements to estimate an initial health of turbine engine components, and determine an operational value of the set of health parameters based on a second set of sensor measurements to estimate an operational health of the turbine engine components.

Aircraft having redundant directional control

An aircraft has an airframe with a two-dimensional distributed thrust array attached thereto having a plurality of propulsion assemblies that are independently controlled by a flight control system. Each propulsion assembly includes a housing with a gimbal coupled thereto that is operable to tilt about first and second axes responsive to first and second actuators.

Power generation and distribution for vehicle propulsion

An aerial vehicle includes a hybrid power generation system comprising an engine; a generator mechanically coupled to the engine; and a propulsion system comprising an electric motor electrically coupled to the generator and a rotational mechanism coupled to the electric motor.. .

Meal/beverage trolley convertible to waste trolley

Embodiments of the present disclosure relate generally to trolleys designed for use onboard passenger transportation vehicles. Particular trolleys of this type find particular use onboard aircraft.

Vertical takeoff and landing aircraft

A vertical takeoff and landing aircraft includes a pair of ducted fans adapted to generate lift and thrust, a frame adapted to couple together the ducted fans, a power source adapted to supply power to the ducted fans, and legs adapted to support an airframe at the time of landing, in which one of the ducted fans is inclined tangentially to a rotational direction on the side farther from the other ducted fan.. .

Wing and propeller design for aircraft

In one embodiment, an aircraft includes a number of propellers nprop, wherein each propeller comprises a diameter dprop, has a propeller efficiency ηprop, and is configured to absorb power pprop to rotate at a rate rpm to generate thrust for a flight speed v of the aircraft. The aircraft may further include a total power ptotal absorbed by the propellers that is approximately pprop×nprop, a wing having a circulation distribution, wherein the wing comprises a wingspan b, a drag d that is approximately equal to ptotal×ηprop/v.

System and providing dynamic tactile feedback to a vehicle operator

A system and method is disclosed for providing dynamic tactile feedback. A tactile feedback generator is mounted in each vehicle in a group of vehicles and is coupled to provide a controllable tactile feedback signal to an operator of each vehicle in the group of vehicles upon receipt of an activation signal.

Stringer-less fuselage structure and manufacture

Stringer-less fuselage structures and associated methods of manufacturing are disclosed. In some embodiments, a fuselage structure includes a composite fuselage skin (24) including a plurality of tear straps (32) formed in the composite fuselage skin where each tear strap extends generally along a longitudinal axis of the composite fuselage skin.

Mechanically and electrically distributed propulsion

A distributed propulsion system is described that includes at least one turbine engine including an engine shaft and at least one mechanically driven propulsor, wherein a propulsor shaft of the at least one mechanically driven propulsor is not co-axial with the engine shaft of the at least one turbine engine and is driven by the engine shaft of the at least one turbine engine. The distributed propulsion system further includes at least one generator driven by rotation of at least one of the engine shaft of the at least one turbine engine or the propulsor shaft of the at least one mechanically driven propulsor.

Underwater vehicle

An underwater vehicle comprising: port and starboard thrusters spaced apart in a port-starboard direction, each thruster being oriented to generate a thrust force in a fore-aft direction perpendicular to the port-starboard direction; a vertical thruster which is oriented to generate a thrust force substantially perpendicular to the fore-aft and port-starboard directions; port, starboard and vertical ducts which contain the port, starboard and vertical thrusters respectively, each duct providing a channel for water to flow through its respective thruster; and a moving mass which can be moved relative to the thrusters in the fore-aft direction to control a pitch of the underwater vehicle.. .

Articulating moored profiler system

The present invention relates to profiler systems and methods for observing and sensing aspects of a body of water at a plurality of depths. A water profiler is disclosed comprising, generally, a vessel body connected to an external mooring cable via an attachment means, a drive means for maneuvering the vessel body longitudinally about the mooring cable; an articulating mechanism; and a sensor array capable of measuring a parameter for study wherein the vessel body is capable of articulating about the mooring cable.

Seat post for bicycles and other vehicles in general

The seat post for bicycles and other vehicles in general includes at least one support element associated with a frame of a bicycle, which can be placed along a substantially vertical direction of installation and able to support a saddle for bicycles having at least one fastening element, at least one positioning assembly placed at the top extremity of the support element and having at least a locking device able to retain the fastening element, and the locking device having at least one damping layer able to dampen vibrations transmitted from the ground and other unevenness.. .

Side splitter and splitter assembly with dive plane feature

A front splitter assembly includes a front splitter having a first end and a second end, a first side splitter at the first end and a second side splitter at the second end. Each side splitter includes a contoured body.

Steering display device of work vehicle and work vehicle

A steering display device of a work vehicle visually displaying a steering state of control wheels of the work vehicle, includes a display and an image generation unit. The display displays a rectangular frame representing a vehicle width of the work vehicle and a pointer representing a state of a steering of the control wheels as graphic information, and the image generation unit rotates the pointer about a rotation axis of the pointer and widens or narrows the rectangular frame based on the steering of the control wheels.

System and estimating steering torque

A system and a method for estimating a steering torque, may include receiving, in a controller, information including a value of a yaw rate and a value of a lateral acceleration of a vehicle collected in the vehicle in real time; determining and estimating, in the controller, a value of a rack force from the received information and a setting information using a predetermined model formula of estimating the rack force; and generating, in the controller, an estimated value of the steering torque according to an operation of a steering wheel of a driver from the estimated value of the rack force using a predetermined value of a gain.. .

Mobile child support device

A mobile child support and entertainment device includes a base panel having roller elements for rolling support along a support surface, an upper support body having a seat positioned generally centrally therein for receiving a child, and at least one support leg extending between the base panel and the upper support body. The device allows a caregiver to move the child in the device from location to location, and provides entertainment and activity for the child.

Vegetation detection and alert system for a railway vehicle

The present disclosure relates generally to vegetation detection and, in particular, to a vegetation detection and alert system for a railway vehicle.. .

Generator system for rail vehicles

The disclosure relates to a generator system for rail vehicles, for example, a system including a generator with a rotor and a stator, and a journal box unit. The journal box unit may include a bearing for mounting an axle, and a bearing housing.

System for monitoring the physical state of a vehicle occupant

A system configured to determine a physical state of a vehicle occupant within a vehicle is described herein. The system includes an electrode in contact with the vehicle occupant and containing nano-scale metal fibers or carbon nanotubes and a controller that determines the physical state of the vehicle occupant based on an output of the electrode.

Control vehicle

A control apparatus for a vehicle that includes an engine includes an electric generator, a throttle valve, an electric generator control unit, and a throttle control unit. The electric generator is configured to be coupled to the engine.

Systems and methods for response vehicle pump control

A response vehicle includes an engine, a transmission coupled to the engine, a pumping system operatively engaged with the transmission and thereby configured to at least selectively receive mechanical energy generated by the engine via the transmission, and a central controller communicably coupled to the engine, transmission, and pumping system. The pumping system has an input configured to interface with a water source and receive an inlet flow of water.

Vehicular motion control device and method

Provided are a vehicular motion control device and method such that, even when a vehicle is turning, the target trajectory can be followed while maintaining traveling stability, with a reduced sense of incongruity felt by the driver. This vehicular motion control device is equipped with: a target trajectory acquisition unit that acquires a target trajectory for a vehicle to travel; and a speed control unit that increases or decreases the longitudinal acceleration generated in the vehicle, the longitudinal acceleration being positive in the vehicle travel direction.

Vehicle and supporting driving safety of vehicle

An apparatus for controlling driving of a vehicle includes an active safety driving device for changing a driving mode of the vehicle from a normal driving mode to an active safety driving mode, a front detection sensor for recognizing a front vehicle as a control target dangerous vehicle when the front vehicle attempts to change into a lane in which the vehicle travels, and a vehicle control device for determining whether to generate a margin shaping for the control target dangerous vehicle, and for controlling the active safety driving device based on the margin-shaped control target dangerous vehicle when the margin shaping is applied to the control target dangerous vehicle.. .

Automated driving commands interpretation for stability control

A control system for providing a yaw moment control action is provided. The control system comprises a command interpreter and a control segment.

Electric vehicle and active safety control system and method thereof

The present disclosure discloses an electric vehicle and an active safety control system and method thereof. The system includes: a wheel speed detection module configured to detect a wheel speed to generate a wheel speed signal; a steering wheel rotation angle sensor and a yaw rate sensor module, configured to detect state information of the electric vehicle; a motor controller; and an active safety controller configured to receive the wheel speed signal and state information, obtain state information of a battery pack and state information of four motors, obtain a first side slip signal or a second side slip signal according to the wheel speed signal, the state information, the battery pack and the four motors, and according to the first side slip signal or the second side slip signal, control four hydraulic brakes of the electric vehicle and control the four motors by using the motor controller..

Hybrid vehicle and controlling the same

An electronic control unit of a hybrid vehicle controls an engine and an inverter to execute inverterless traveling. The inverterless traveling is a traveling state where the inverter is set to a gate blocking state, and where a reaction force of a torque that is output by a rotating electric device when the rotating electric device to be rotated by output of the engine generates electric power is applied to an output shaft.

Clunk mitigation techniques for pedal tip-in and tip-out events

A control system and method for a vehicle having a powertrain comprising a torque generating system and an automatic transmission each utilize a pedal position sensor configured to measure a position of an accelerator pedal of the vehicle and a controller configured to, based on the accelerator pedal position, detect a pedal tip-in or tip-out event and, in response to detecting the pedal tip-in or tip-out event: (i) determine a desired output torque for the torque generating system corresponding to the pedal tip-in or tip-out event and (ii) command the torque generating system to gradually transition, over a period, from its current output torque to the desired output torque to mitigate clunk caused by abrupt contact between gear teeth of the torque generating system shaft and the automatic transmission shaft.. .

Hybrid vehicle

A hybrid vehicle includes: an engine; a catalyst; a motor generator; and a drive control unit. The catalyst is provided in an exhaust path of the engine.

Hybrid vehicle and controlling engine start

A method of controlling a hybrid vehicle includes steps of determining a first torque, the first torque being a currently required torque, determining a second torque to be generated at a near-future time, or a predicted acceleration at the near-future time, determining a predicted speed at the near-future time based on a current speed and the second torque or the predicted acceleration, determining when it is determined that one of engine start and shift conditions is satisfied at a current time based on at least one of the first torque and the current speed, whether the remaining one of the engine start shift conditions is satisfied at the near-future time, and controlling an event corresponding to the satisfied condition at the current time is delayed or an event corresponding to the satisfied condition at the near-future time is advanced when the remaining one condition is satisfied.. .

Hybrid vehicle and controlling mode transition thereof

A method of performing a mode transition in a hybrid vehicle includes: determining a transition from a first mode to a second mode; comparing a driver's required torque with a maximum torque of an electric motor, determining a compensation torque when the driver's required torque is greater than the maximum torque; and determining a first torque to be output from an engine and a second torque to be output from a hybrid starter generator, which is connected to the engine, in consideration of the compensation torque and a system efficiency.. .

Energy recovery system

A mining machine is provided. The mining machine includes a frame.

Method and system for controlling the braking of an aircraft equipped with a thrust-reversal system

The present disclosure relates to a method of controlling the braking of an aircraft equipped with a landing gear bearing braked wheels, the aircraft being propelled by jet engines and equipped with a thrust reversal system, the method involving the steps of estimating the grip/adhesion of the braked wheels and activating the thrust-reversal system or modulating the reverse-thrust generated by the thrust-reversal system if this system is already activated, based on the estimated grip/adhesion.. .

Emergency park brake system

An emergency park brake system of an aircraft may include a user input interface configured to receive actuation input from a user. The emergency park brake system may also include a first displacement sensor and a second displacement sensor that are both coupled to the user input interface.

Energy-absorbing knee bolster

A vehicle component may include a crossbeam, a cylinder, a piston, a panel, and a heterogeneous mixture. The cylinder has a chamber and is fixed relative to the crossbeam.

Interactive skin for vehicle

A panel of a vehicle may be provided with or configured to provide interactive skin. The interactive skin may be configured for accepting touch input from a user.

Display control a vehicle

A display control system of a vehicle includes a surround view module configured to generate a surround view including a predetermined top view image of vehicle and one or more features located within a predetermined area around the vehicle. A parking module is configured to selectively generate a parking signal when, for at least a predetermined period, a vehicle speed is less than a predetermined speed and at least one of: (i) an accelerator pedal position is less than a predetermined position; (ii) a brake pedal position indicates a request for vehicle braking; and (iii) a magnitude of a steering wheel angle is greater than a predetermined steering wheel angle.

Peripheral image display device and displaying peripheral image for construction machine

A peripheral image display device for displaying a peripheral image around a construction machine including at least two imaging units capturing the peripheral image around the construction machine; an image combining unit that combines at least two images obtained from the at least two imaging units to form a single projection image, the at least two images including an overlapping area overlapping between the at least two images; a guideline setting unit that sets a guideline, which includes at least two color information pieces, on the projection image formed by the image combining unit at a position a predetermined distance apart from the construction machine; a guideline generating unit that generates the guideline on the projection image based on setup information obtained by the guideline setting unit; and a display unit that displays the projection image having the guideline generated by the guideline generating unit on a screen.. .

Vehicle hatch clearance determining system

A vehicle hatch clearance determining system includes a plurality of cameras disposed at the vehicle and a control having a processor for processing image data captured by the cameras to determine structure and objects present in the fields of view of the cameras while the vehicle is being driven during a parking event. The control, responsive to processing of captured image data, determines and stores information pertaining to structure and objects present in the fields of view of the cameras during the parking event.

Capacitive sensor and switch assembly with decorative conductive component

A capacitive sensor and switch assembly is provided. The assembly includes a first electrode forming a decorative conductive component on a vehicle, and a second electrode dielectrically isolated from the first electrode and electrically coupled therewith to generate an activation field.

Systems and methods for illumination control and distribution during a vehicle bank

A bank angle of a vehicle can be accurately calculated using yaw axis data and roll axis data, and based on the calculated bank angle, vehicle illumination optics can be controlled to maintain a pattern of distributed light from the illumination optics to be generally horizontal. The calculated bank angle may be zeroed when the yaw axis data equals zero.

Solar panel power point tracker integrated with vehicle electrical system

A voltage quality module (vqm) function and a solar power generation function are integrated by sharing a single voltage converter (vc) within the electrical system of an automotive vehicle with an electric-start internal combustion engine. The cost of adding solar power generating capabilities to vehicles, the packaging complexities of the systems, and the number of added components are all decreased.

Optimizing regenerative braking efficiency in a hybrid vehicle

An autonomous or semi-autonomous vehicle is provided that is capable of braking itself without a driver depressing the brake pedal. The vehicle has a powertrain that includes an engine, a transmission, and a motor with a connected battery to provide regenerative braking capabilities.

Support to handle an object within a passenger interior of a vehicle

The disclosure related to a system to support handling of an object located within a passenger interior of a motor vehicle and not connected to the motor vehicle. The system has a sensor unit to detect a distance of the object to a storage area available within the passenger interior.

Electric and hydraulic drive system and methods

An electric propulsion system and methods are described that include an internal combustion engine coupled to a generator to provide power to one or more electric motors. Configurations are shown that include excitation control of power from the generator.

Hybrid vehicle transmission

A hybrid vehicle transmission includes input and output shafts, first and second motor/generators, a first planetary gear train in which one rotary element of three rotary elements is connected to the input shaft and another thereof is connected to the first motor/generator, a second planetary gear train in which one of three rotary elements is connected to the output shaft and another thereof is connected to the second motor/generator, a first external gear pair consisting of a first gear, connected to a remaining rotary element of the first planetary gear train, and a second gear, connected to a remaining rotary element of the second planetary gear train, and a second external gear pair consisting of a third gear, connected to the input shaft, and a fourth gear directly connected to one rotary element of the second planetary gear train.. .

Articulated bus

Provided is an articulated bus including a front vehicle including a steering wheel and a rear wheel positioned on a rear side of the steering wheel in a front-rear direction of a vehicle, a rear vehicle disposed on a rear side of the front vehicle in the front-rear direction of the vehicle and mounted with an engine, an articulating portion that swingably connects the front vehicle and the rear vehicle to each other, and a hybrid system including an electric generator that functions as an electric motor and a generator, and an hv battery that stores electric energy generated by the electric generator and supplies electric energy to the electric generator, in which the hv battery is disposed on a roof of the front vehicle.. .

Vehicle heat management device

A vehicle heat management device includes a first circulator section, a second circulator section, and a flow rate change section. The first circulator section is provided at a first flow path of a first circulation path, and circulates a first heat exchange medium in the first circulation path, the first flow path passing a first heat exchanger, a second flow path passing a first expansion valve and a second heat exchanger, a third flow path passing a second expansion valve and a heat absorption section.

Electromagnetic suspension device

An electromagnetic suspension device includes: an electromagnetic actuator that generates a driving force related to vibration damping of a vehicle body by an electric motor; a rotational angle acquisition unit that acquires a rotational angle of the electric motor; a rotational angle acceleration calculation unit that calculates a rotational angle acceleration of the electric motor based on the rotational angle; ecu that performs driving force control including inertia compensation control of the electromagnetic actuator based on the rotational angle acceleration; and a relative speed calculation unit that acquires a relative speed between above- and below-spring members. In an area in which a relative speed exceeds a predetermined relative speed threshold, the ecu corrects an amount of inertia compensation so that the amount of inertia compensation is decreased, as compared with an area in which a relative speed value is the relative speed threshold or less..

Clamping plates and gas spring assemblies as well as suspension systems and methods including same

A clamping plate is dimensioned to secure a flexible spring member to an end member for forming a gas spring assembly. The clamping plate includes a clamping plate wall with an axis and opposing surface portions oriented transverse to the axis.

Pressure based wireless sensor and applications thereof

A radio frequency identification (rfid) tag includes an antenna, an analog front end, a processing circuit, and memory. The analog front end includes a power circuit, a tuning circuit, a transmitter, and a receiver.

Parameterized continuous query templates

Techniques for managing parameterized continuous query templates are provided. In some examples, a continuous query may be generated based at least in part on one or more selections of one or more business logic templates and business event parameters associated with a user.

Vehicle wheel supporting rolling bearing unit

A vehicle wheel supporting rolling bearing unit includes a bearing part having a stationary side bearing ring member which is supported and fixed to a suspension device and non-rotatable in a use state and a rotation side bearing ring member which is coupled and fixed to a vehicle wheel and rotate together with the vehicle wheel, an electric generator which generates electric power to be supplied to a sensor provided on the vehicle wheel, a battery which stores the electric power generated by the electric generator, and a wireless communication device which wirelessly communicates an output signal of the sensor with an electronic equipment arranged on a vehicle body side. The stator is supported and fixed to the stationary side bearing ring member, and the rotor, the battery and the wireless communication device are supported and fixed to the rotation side bearing ring member..

Generating mechanically rendered objects from digital input

Systems, methods, and computer-readable media are disclosed for generating mechanically rendered objects from digital input. In one embodiment, an example method may include generating, by a computer processor(s) coupled to at least one memory, a digital handwriting file comprising one or more digital characters, wherein a first digital character has a first glyph and a second glyph.

Structurally compact backlit display assembly

A display assembly, having a base comprised of polymeric material, and having a front wall of at least one hundred square centimeters in area, and a rearward-extending base peripheral wall of at least 0.5 cm height. The front wall has raised regions and recessed regions that extend at least as far back as the peripheral wall at its furthest rearmost extent, so that when the base is placed against a flat surface the back of the recessed regions touches the flat surface.

Powering a power monitor

A power supply circuit for powering a power monitor includes an x type capacitor to isolate low voltage from alternating current (ac) mains, a schottky diode to generate a direct current (dc) output voltage from the low voltage, and a low dropout regulator to regulate the dc output voltage for powering the power monitor, the power monitor to protect a printer pen of a printer during ac voltage sags.. .

Inkjet printer

An inkjet printer forms ink dots of a first ink and ink dots of a second ink on a recording medium. The inkjet printer performs first screen processing on image data of the second ink to generate a first dot group including the ink dots of the second ink, and performs second screen processing on image data of the second ink to generate a second dot group including the ink dots of the second ink.

Inkjet printer

An inkjet printer includes a first ink head to eject a first ink, and a second ink head to eject a second ink. A generator generates dot groups including at least a first dot group and a second dot group including ink dots of the second ink.

Inkjet printer and printing method

An inkjet printer ejects a first ink including multiple colors and a second ink. A controller generates dot groups including an underlying layer dot group and an image dot group from ink dots of the first ink of each of the colors.

Liquid ejecting head, manufacturing method thereof, and liquid ejecting apparatus

There are provided a conductive base; a plurality of head main bodies which are held by the base and each have a switching element and a pressure generating element for discharging a liquid in a pressure generating chamber; a plurality of covers which are separated from the base, at least one of the pressure generating element and the switching element being sandwiched between the base and each of the covers; and a plurality of conduction portions which each conduct the base and the cover to each other at a plurality of locations.. .

Metal and graphite laminate

The present invention is a laminate sheet having two laminae. The first lamina is a relatively hard material having first and second surfaces.

Additive fabrication support structures

Techniques for generating a support structure for an object are provided. In some embodiments, one or more regions of the object are identified as one or more regions to which mechanical support is to be provided and one or more support points within at least a first region of the one or more regions are identified.

Method and printing three-dimensional (3d) objects

Some embodiments of the invention may be related to a system and method of printing a three-dimensional (3d) object and a support construction for the 3d object. The system may include a printing unit and a supply system for supplying a body material and a support material to the printing unit.

Generating three-dimensional objects with target surface roughness

An agent distributor may be to selectively deliver agent at a first contone density and at a second contone density different from the first contone density respectively onto an interior portion and a surface portion of successive layers of build material in respective first and second patterns in accordance with data representing a three-dimensional object to be generated, so that the build material is to solidify to form slices of the three-dimensional object in accordance with the first and second patterns, and so that the three-dimensional object is to achieve a target surface roughness as a result of the second contone density of the second pattern.. .

A three-dimensional imaging modeling a colored three-dimensional object

The present invention relates to a three-dimensional imaging apparatus for modeling a colored three-dimensional object on a layer-by-layer basis in accordance with a computer aided design (cad) image of the object. The apparatus includes a printhead unit comprising a melting chamber; a primary feeding channel arranged between a supply of primary modeling material in solid state, preferably in filament form, and the melting chamber; driving means to drive and regulate the flow of the primary modeling material through the primary feeding channel toward the melting chamber; secondary feeding channels each of which is arranged between a supply of colorant material in solid state, preferably in filament form and the melting chamber; driving means to drive and regulate the flow of the solid colorant materials in accordance with a predetermined computer generated coloring pattern to the melting chamber; heating means arranged adjacent to the melting chamber for supplying heat energy inside the melting chamber for converting the primary modeling material and the colorant materials therein from a solid state to a flowable fluid state to obtain a colored modeling material; a dispensing nozzle through which the colored modeling material in flowable fluid state is conveyed from the melting chamber to an object supporting platform positioned at a predetermined distance from the dispensing nozzle and motion devices coupled to said platform and said nozzle for moving said nozzle and said platform relative to one another in a plane defined by first and second directions and in a third direction orthogonal to said plane to deposit said flowable fluid material into a three-dimensional object..

Polymer spray deposition methods and systems

A method of creating a three-dimensional object includes generating a spray from a fluid by stretching the fluid between two diverging surfaces into a fluid filament until the fluid filament breaks into a plurality of droplets and forms the spray, entraining the spray in a carrier gas flow, directing the carrier gas flow toward a target surface through a multi-nozzle array, and repeatedly applying the carrier gas flow on a target surface to form the three-dimensional object by controlling the direction of the carrier gas flow toward the target surface.. .

Laser based tyre mold vent cleaning process and device

A vent hole cleaning system is disclosed. The cleaning system is comprised of a housing containing a work table and a support column.

Dynamically directed workpiece positioning system

In various embodiments, a dynamically directed workpiece positioning system may include a transport, a sensor positioned to detect a workpiece on the transport, a cutting member positioned along or downstream of the transport, and a computer system. The sensor may scan the workpiece as the workpiece is moved relative to the transport by a human operator or a positioning device.

Eye in-hand robot

A robot includes a gripping member configured to move and pick up the object, a camera affixed to the gripping member such that movement of the gripping member causes movement of the camera, the camera configured to measure and store data related to intensity of light and direction of light rays within the environment, an image processing module configured to process the data to generate a probabilistic model defining a location of the object within the environment, and an operation module configured to move the gripping member to the location and pick up the object.. .

Method of teaching robot and robotic arm control device

By repeating for each control axis, that an axis angle of each control axis of an arm is detected during a direct teaching of a robot, a current position of a standard point defined on the arm or a tool is obtained based on the axis angle, a position instruction value that uses a position obtained by projecting the current position on a given movement route (moving direction) is generated as a target position, and each control axis is driven based on the position instruction value, until a deviation of an instruction angle corresponding to the position instruction value and the detected axis angle, or a deviation of the position instruction value and the current position of the standard point corresponding to the detected axis angle reaches a given value or below, the robot is taught, after the deviation becomes the given value or below, positional information on the arm.. .

Control device for motor drive device, control device for multi-axial motor, and control motor drive device

Motion control of a robot arm is performed via a reducer connected to a motor. A controller thereof includes a thrust control unit that generates motor position command value based on an input thrust command value, and a motor control unit that generates a current value based on the motor position command value.

Parallel link robot and operation apparatus

[solving means] a parallel link robot includes a movable portion, a base, a plurality of drive sources, a plurality of links, and a tension member. The plurality of drive sources are attached to the base.

Apparatus and cmp pad conditioning

A chemical mechanical polishing apparatus including a conditioning head having a first pressure sensor and a controller configured to adjust at least one of a position or a rotation of the conditioning pad responsive to the first pressure data. The conditioning head is adjustable between a first position and a second position, the conditioning head and a polishing pad are in contact when the conditioning head is in the second position, and the first pressure sensor generates first pressure data when the conditioning head is in the second position..

Air tool monitoring apparatus, air tool incorporating same, system for monitoring multiple air tools equipped with same, and methods of using same

An air tool monitoring apparatus includes a housing having a hollow chamber formed therein, and also having an inlet and an outlet formed therein, each of the inlet and an outlet in communication with the chamber. The apparatus also includes first and second sensors for sensing condition indicative of tool usage and wear, a battery disposed in the housing, a generator for recharging the battery, and a microprocessor operatively connected to the housing and including a timer, a memory storage module, and a unique identifier.

Control device for machine tool performing oscillation cutting

A control device includes a position command generation part, an oscillation command generation part, and a storage part for storing machining operation conditions and servo control conditions. The oscillation command generation part includes an estimation part which estimates an oscillation amplitude and an oscillation frequency of an oscillation command based on a rotation speed of a workpiece and a position command generated by the position command generation part, and a determination part which determines whether or not the estimated oscillation frequency is an optimum value based on the machining operation conditions and the servo control conditions..

Control device for machine tool performing oscillation cutting

A control device includes a control part which generates a torque command based on a resultant command, which is obtained by adding a position deviation, which is the difference between a position command and the actual position of a feed shaft, to an oscillation command to control the feed shaft, and an elastic deformation amount calculation part which calculates the elastic deformation amount of a structure composed of a tool or workpiece and the feeding mechanism therefor based on the torque command. An oscillation command generation part generates the above oscillation command based on the rotation speed of the workpiece, the position command of the feed shaft, and the above elastic deformation amount..

Systems and methods for welding electrodes

The invention relates generally to welding and, more specifically, to welding wires for arc welding, such as gas metal arc welding (gmaw) or flux core arc welding (facw). In one embodiment, a tubular welding wire includes a sheath and a core, and the core comprises a rare earth silicide component (cerium, lanthanum, or a combination thereof).

Laser machining apparatus that irradiates guide beam to project guide pattern indicating setup position for workpiece

A laser machining apparatus includes: a laser beam emission device; a guide beam emission device; a scanner; a processor; and a memory. The memory stores a set of computer-readable instructions therein.

Short arc welding system

A system for controlling a weld-current in an arc welding apparatus for short arc welding comprising a current regulator included in a voltage feedback loop from a power supply to a welding electrode and a ramp generator arranged to provide current ramps during a short circuit phase at said welding electrode.. .

Hole drilling elastically deformed superalloy turbine blade

A method includes applying a force to elastically deform at least a portion of a superalloy turbine blade from a relaxed, initial position to an elastically deformed position. The at least a portion of the superalloy turbine blade has a curvature in the elastically deformed position not present in the relaxed, initial position.

Method for the gear manufacturing machining of a workpiece

The present disclosure relates to a method for the gear manufacturing machining of a workpiece in which a hobbing machining of the workpiece takes place to generate a gearing geometry of the workpiece, wherein the workpiece is gear manufacturing machined by gear skiving in addition to the hobbing machining.. .

Methods and systems for coherent imaging and feedback control for modification of materials

Methods and systems are provided for using optical interferometry in the context of material modification processes such as surgical laser, sintering, and welding applications. An imaging optical source that produces imaging light.

Printed object correction via computer vision

A camera assembly is employed in additive manufacturing to improve the fidelity of a printed object. The camera may scan the surface of a build plate of a 3d printer and an object as it is being printed to generate image data.

Calibration of 3d printer via computer vision

A camera assembly is employed in additive manufacturing to improve the fidelity of a printed object. The camera may scan the surface of a build plate of a 3d printer and an object as it is being printed to generate image data.

Guided keeper assembly and metal forming dies

A guided keeper assembly includes a base, at least one marginal fastener aperture to detachably mount the base to an associated die shoe, and a central guide aperture. A guide pin is closely received in the central aperture of the base.

Method and sorting particles

A method and apparatus for sorting particles moving through a closed channel system of capillary size comprises actuators and chambers for selectively generating a pressure pulse to separate a particle having a predetermined characteristic from a stream of particles. The particle sorting system may further include a buffer for absorbing the pressure pulse.

Vibration piston arrangement in the squeezing cylinder of a track tamper

For tamping a track, tamping tines are squeezed towards one another in pairs by a squeezing cylinder. A vibration is superimposed on a linear lift motion of a squeezing piston movable in the squeezing cylinder.

Ultrasound transducer

An ultrasound transducer includes a plurality of piezoelectric elements that are layered in the thickness direction and that generate a longitudinal vibration in the thickness direction. The plurality of piezoelectric elements are arranged so that the thicknesses thereof are sequentially larger from the antinode side of the longitudinal vibration towards the node side of the longitudinal vibration..

Linear droplet generating device

A nozzle plate (201) for use in a liquid droplet production apparatus and such apparatus, the nozzle plate comprising a flexible substrate having a linear array of nozzles that extend through said plate, said nozzles being arranged in at least one line, forming thereby a nozzle-bearing region, wherein the substrate is curved so as to impart an increased longitudinal stiffness to it. The apparatus comprises a piezo actuator (202, 203), which may have slots (211) separating fingers acting on the nozzle plate (201).

Dispensing assemblies and related methods

A dispensing assembly for dispensing fluid generally includes a container having a handle located toward an upper portion of the container, and a sprayer having arms extending away from the sprayer. The arms of the sprayer define a channel configured to receive at least part of the handle of the container within the channel to thereby couple the sprayer to the container.

Cartridge for an aerosol-generating system

There is provided a cartridge for an aerosol-generating system, the cartridge including a liquid storage container containing: a first liquid composition and a second composition; a plurality of capsules, each capsule encapsulating the second composition to separate the second composition from the first liquid composition, each capsule including a frangible shell encapsulating the second composition; a capsule retainer; and an outlet in the liquid storage container configured to deliver liquid from the liquid storage container, the capsule retainer substantially preventing any frangible shells, or parts thereof, from exiting the cartridge through the outlet. An aerosol-generating device configured to receive the cartridge to form an aerosol-generating system is also provided..

Method and converting infectious waste material into material usable as fuel for a cement kiln

An infectious waste treatment system and method for decontaminating infectious waste employ a thermal friction extruder (20) in which first and second interleaved counter-rotatable augers (40, 42) driven by a variable speed motor include reverse pitch flight sections (62, 72) that urge waste material in a direction opposite to that of the flow stream and into engagement with the back sides of friction plates (50, 52). This increases the amount of heat generated by the extruder.

Cone crusher

The present disclosure provides a generally cylindrical bowl support for a cone crusher which includes a plurality of evenly, circumferentially spaced ears around the periphery of the support. The ears are designed to have clamping cylinders mounted thereto to provide protection from tramp iron and the like passing through the cone crusher.

Three-dimensional microfluidic platform and manufacturing the same

A three-dimensional microfluidic platform including a substrate and a heterogeneous structure is provided. The heterogeneous structure located on the substrate includes prepolymer pattern, cured products, or a combination of at least one prepolymer patterns and at least one cured products, where the material characteristics of the cured products are different from each other, and the material characteristics of the prepolymer patterns are different from each other..

Porous materials

Porous materials (such as organic polyamine cage compounds) and methods of stabilising porous materials which are otherwise prone to pore-collapse are described. Such stabilisation is accomplished through the use of molecular ties to create bridges between reactive groups of a (potentially) porous material to thereby strengthen and stabilise the porous structure.

Nano-bubble water generating apparatus containing an application gas

A nano-bubble water generating apparatus containing an application gas includes a motor, a pump integrated with the motor for supplying liquid, typically water, from an inlet pipe under a predetermined pressure through a supplying pipe to a pressure tank, a nano-bubble water generating tube mounted at the water entrance of a pressure tank, an electronic control portion, a pressure adjuster including an outer air inflowing portion to introduce an outer air or a specific gas supplied thereinto to control a pressure in the pressure tank, uniformly and a pressure adjusting portion airtightly coupled on the upper portion of the outer air inflowing portion to adjust an amount of outer air or specific gas to be supplied, and a nano-bubble water expanding tube for expanding and shattering nano-bubble water through an outlet pipe from the pressure tank, so that the size of the nano-bubble water is better micronized.. .

Integrated system for wet desulfurization using a suspension bed and regeneration

Provided is an integrated system for wet desulfurization using a suspension bed and regeneration, comprising a suspension bed reactor, a gas liquid separation tank, a flash evaporation tank and an oxidation regeneration tank that are connected in sequence. The integrated system is adapted to reduce the sulfur content in the hydrogen sulfide containing gas from 2.4-140 g/nm3 to 50 ppm or less by using a suspension bed, so that the desulfurization efficiency is 98% or more.

Renewable high efficient desulfurization process using a suspension bed

Provided is a renewable high efficient desulfurization process using a suspension bed, comprising mixing the desulfurization slurry with a hydrogen sulfide containing gas to obtain a first mixture, and passing the first mixture into a suspension bed reactor from bottom to top, with controlling the first mixture to have a dwell time of 5-60 minutes in the suspension bed reactor to allow they contact and react sufficiently with each other; and subjecting a second mixture obtained from the reaction to gas liquid separation to produce a rich solution and a purified gas, feeding the purified gas into a fixed bed reactor for carrying out a second desulfurization to obtain a second purified gas, subjecting the resulting rich solution to flash evaporation and then reacting with an oxygen-containing gas for carrying out regeneration. The process may reduce the sulfur content in the hydrogen sulfide containing gas from 2.4-140 g/nm3 to 50 ppm or less by using a suspension bed, and further reduce the sulfur content to less than 10 ppm in conjunction with a fixed bed.

High efficient desulfurization-regeneration system using a suspension bed

Provided is a high efficient desulfurization-regeneration system using a suspension bed, comprising a suspension bed reactor, a gas liquid separation tank, a flash evaporation tank and an oxidation regeneration tank that are connected in sequence, and a fixed bed reactor connected to the exhaust port of the gas liquid separation tank. The system adopts suspension bed to reduce the sulfur content in the hydrogen sulfide containing gas from 2.4-140 g/nm3 to 50 ppm or less, and further reduce the sulfur content to less than 10 ppm in conjunction with a fixed bed.

Systems, methods, and devices for direct conversion of methane

Non-oxidative direct methane conversion (ndmc) to value-added products, such as h2, c2 hydrocarbons, and aromatics, occurs within a reactor heated to an elevated temperature. The reactor can have a first volume, where a feed gas including methane is provided, separated from a second volume, where a sweep gas is provided, by a dense thin film membrane supported on a porous wall.

Dehumidifier

A dehumidifier includes: a housing; a refrigerant circuit configured to allow low gwp refrigerant to circulate therethrough, the refrigerant circuit including a compressor having a variable operating frequency, a condenser, a pressure reducing device, and an evaporator, which are provided in the housing, the low gwp refrigerant being flammable and having a value of gwp of 6 or less; a blowing fan, which is provided in the housing, and is configured to take in air in a room into the housing and cause the taken-in air to pass through the evaporator and the condenser before blowing out the air from the housing into the room; and a water storage tank, which is provided below the evaporator, and is configured to accumulate dew condensation water generated in the evaporator, a number of refrigerant paths passing through the evaporator being greater than a number of refrigerant paths passing through the condenser.. .

Renewable wet desulfurization process using a suspension bed

Provided is a renewable wet desulfurization process using a suspension bed, comprising mixing the desulfurization slurry with a hydrogen sulfide containing gas to obtain a first mixture, and passing the first mixture into a suspension bed reactor from bottom to top, with controlling the first mixture to have a dwell time of 5-60 minutes in the suspension bed reactor to allow they contact and react sufficiently with each other; and subjecting a second mixture obtained from the reaction to gas liquid separation to produce a rich solution and a purified gas, subjecting the resulting rich solution to flash evaporation and then reacting with an oxygen-containing gas for carrying out regeneration. The process of the present invention may reduce the hydrogen sulfide content in the hydrogen sulfide containing gas from 2.4-140 g/nm3 to 50 ppm or less, so that the desulfurization efficiency is 98% or more.

Wet desulfurization process using a suspension bed

Provided is a wet desulfurization process using a suspension bed. The process comprises mixing desulfurization slurry with a hydrogen sulfide containing gas to obtain a first mixture, and passing the first mixture into a suspension bed reactor from bottom to top, with controlling the first mixture to have a dwell time of 5-60 minutes in the reactor to allow they contact and react sufficiently with each other; and subjecting a second mixture obtained from the reaction to gas liquid separation to produce a purified gas.

Methods, systems, and apparatuses for acoustically separating and washing particles

A method of washing particles in an acoustic chamber includes (a) flowing a suspension of particles in a suspension medium through a standing wave generated in a standing wave volume of the acoustic chamber to accumulate within the acoustic chamber at least some of the particles as raw particle concentrate; and (b) flowing a wash medium through the acoustic chamber to wash within the acoustic chamber at least some of the particles of the raw particle concentrate, and retaining within the acoustic chamber at least some washed particles.. .

Mechanical filter element, apparatus and method

The present disclosure a mechanical filter element (2) for forming a static filter pack (11) to perform mechanical filtration of a liquid. The mechanical filter element (1) has one or more filter cell (19).

Extractor arrangement for processing materials with fines

An extraction system may include a primary extractor that is configured to process a main feedstock undergoing extraction and a secondary extractor configured to process particulate matter separated from miscella produced on the primary extractor. In some configurations, the secondary extractor is an immersion extractor that has a solvent stream flowing in a counter current direction to a direction which the particulate matter flows through the extractor.

Game channels in messaging applications

In one embodiment, a method includes receiving an indication a first user is accessing a game, wherein the first user has a first user identifier (id); generating, based on the first user id, a first hashed id for the first user; providing the first hashed id to a game bot associated with the game, the game bot being a software agent configured to act automatically on behalf of the game; receiving, from the game bot, a request to initiate a message thread between the game bot and the first user on a messaging application running on a first client system of the first user; and sending instructions for presenting the message thread on the messaging application, the message thread comprising one or more messages referencing in-game actions in the game.. .

System and event-based gaming

A system and method provides an event-based game to a plurality of players including displaying an event, the event having an end, generating a plurality of different pools for the event, wherein each of the different pools includes a plurality of groups and each of the groups includes a plurality of participants, determining eligible participants for each of the different pools, randomly assigning one eligible participant of the plurality of participants from one of the groups to a plurality of eligible participants of the plurality of participants from another one of the groups, allowing a player to place a wager on the event, selecting one of the eligible participants from each of the different pools, printing a ticket with the selected participants, dispensing the ticket to the player, and awarding a prize based on a highest total number of points at the end of the event.. .

Method and system for renewing screen

There is provided a screen update method and system including: a first step of identifying image resource data associated with a first image update event from a predetermined basic recording space in case that the first image update event occurs, a second step of loading the identified image resource data in a buffer space including a plurality of buffers, in which the image resource data are loaded in rotation on the buffer by a frame, respectively, a third step of sequentially determining the image resource data loaded on the buffer for each the buffer, rendering the determined image resource data, and generating a first image at a first frame rate, a fourth step of generating a second image associated with a second image update event at a second frame rate in case that the second image update event occurs, a fifth step of compositing the first image with the second image to generate an entire image, and a sixth step of displaying the entire image on a predetermined display means.. .

Every county wins

On the designated draw date a computer generated program will pick a ticket that has been sold in that county. The person with that ticket will be the winner.

Golf tee encapsulating spark induction material and improving golf performance

A golf tee has a contact alert material encapsulated therein. The golf tee includes a top portion with top, side and bottom walls fixedly attached to a shaft that terminates into a point appointed to be inserted into a ground surface.

Method, apparatus, and system for golf product reconfiguration

A computer program is disclosed for reconfiguring a property-adjustable golf club. The program receives data input corresponding to a current configuration of an adjustable feature of the golf club, and data input corresponding to trajectory adjustment information.

Arrays of accelerating structures and rapid imaging for facilitating rapid radiation therapies

Methods and system for facilitating rapid radiation treatments are provided herein and relate in particular to radiation generation and delivery, beam control, treatment planning, imaging and dose verification. The methods and systems described herein are particularly advantageous when used with a compact high-gradient, very high energy electron (vhee) accelerator and delivery system (and related processes) capable of treating patients from multiple beam directions with great speed, using all-electromagnetic or radiofrequency deflection steering is provided, that can deliver an entire dose or fraction of high-dose radiation therapy sufficiently fast to freeze physiologic motion, yet with a better degree of dose conformity or sculpting than conventional photon therapy..

Knowledge based treatment planning corrected for biological effects

Solutions are provided herein that specifically accounts for biological effects of tissue during radiation planning (such as treatment planning). In one or more embodiments, the biological effects may be calculated by accessing a knowledge base to determine reference data comprising at least one biological characteristic corresponding to the at least one organ, predicting a biological effect for the plurality of identified structures based on the biological characteristic corresponding to the at least one organ, and generating or modifying a radiation plan based on the biological effect.

Phototherapy system and method

The present invention relates to a phototherapy system comprising an led carrier (10) for being arranged on or under a subject (100), a set (12; 24, 26; 36) of leds (13; 23, 25; 33, 35), wherein at least a first subset (12; 24; 34) of leds (13; 23; 33) of said set is arranged in or at the led carrier (10), a control unit (15) for controlling one or more leds (13; 23; 33) of said first subset (12; 24; 34) to switch between an emission mode, in which an led emits electromagnetic radiation in the direction of the subject, and a detection mode, in which an led generates a detection signal in dependence on the electromagnetic radiation incident on the led, and a position determination unit (16) for determining the position of a subject with respect to the led carrier based on the detection signals of one or more leds (13; 23; 33) of said first subset (12; 24; 34) in the detection mode, wherein the control unit (15) is configured to control one or more leds (13; 23, 25; 33, 35) to switch into the emission mode based on the determined position of the subject such that their emitted electromagnetic radiation provides phototherapy for the subject. A vital signs determination unit (17) is provided for determining one or more vital signs of the subject from one or more detection signals generated by one or more leds of said first subset..

External unit for an implantable neuro stimulator system

An external unit for an implantable neuro stimulator system and a method of operating the same, comprising an external coil inductively couplable to an implant coil of an implantable neural stimulator unit when in close proximity to each other. An rf-signal generating module for generating and outputting an rf-signal to the coil for inductive power and/or data transfer to the implantable neural stimulator unit, a measurement unit connected to the coil for measurement of an electrical parameter at the coil and a controller connected to the measurement unit and comprising a comparator and a storage for storing the electrical parameter.

Method of treating parkinson's disease and other movement disorders

The present invention relates, in general, to movement disorders and, in particular, to a method of treating movement disorders, including parkinson's disease.. .

Treatment of biological tissues using subnanosecond electric pulses

A system for treatment of biological tissues is provided. The system can deliver electric pulses to a targeted region within a biological tissue.

Topical neurological stimulation

A topical nerve stimulator patch and system are provided comprising a dermal patch; an electrical signal generator associated with the patch; a signal receiver to activate the electrical signal generator; a power source for the electrical signal generator associated with the patch and an electrical signal activation device.. .

Transvenous treating sleep apnea

A system and method for treating sleep apnea includes inserting an implantable pulse generator subcutaneously within a body of a patient and connecting a lead to the pulse generator. The lead is inserted within the vasculature and advanced transvenously through the vasculature until a stimulation portion of the lead becomes positioned in close proximity to the hypoglossal nerve.

Active medical device with attachment features

Implantable leads of a cardiac stimulus system are disclosed, as well as methods for implanting leads of a cardiac stimulus system. The lead may be comprised of a proximal portion having a coupler for coupling to an implantable pulse generator, an intermediate portion comprising a plurality of electrodes disposed thereon, and a distal portion.

Electrotherapeutic sole and making the same

The present invention is to provide an electrotherapeutic sole and a method for making the same, wherein the electrotherapeutic sole is composed of nitrile-butadiene rubber (38%˜42% by weight), conductive carbon black (37%˜42% by weight), a softening oil (14%˜17% by weight), a processing aid (3%˜5% by weight), and an accelerant (1%˜2% by weight) and has a top portion protrudingly provided with a plurality of electrode protuberances that correspond in positions to the acupoints in a human sole; the electrotherapeutic sole is also provided with a socket, thereby an electrotherapeutic pulse output terminal inserted into the socket can send the electrotherapeutic pulses generated by an electrotherapeutic pulse generator sequentially through the socket and the conductive carbon black in the electrotherapeutic sole to the tips of the electrode protuberances to massage the corresponding acupoints in the human sole.. .

Percutaneous access pathway system and method

An improved method and device are provided for forming and/or maintaining a percutaneous access pathway. The device generally comprises at least one of three type of components: access pathway, insertion device, and attachment device.

Balloon catheter and fluid management system thereof

A method for maintaining a balloon of a balloon catheter at a prescribed pressure of between about 0.2 psi and 1 psi comprises the step of: generating a vacuum within a reservoir defined in a burette that is part of a fluid management system that is configured to controllably inflating and deflating the balloon by circulating balloon fill media along a fluid circuit, wherein generating the vacuum results in formation of a pressure differential along the fluid circuit, thereby allowing the balloon to be maintained at the prescribed pressure between about 0.2 psi and about 1 psi.. .

Steerable medical instrument

The disclosure of this application relates generally to medical devices and in particular to a steerable medical instrument applicable to guide interventional tools and instruments, such as percutaneous biopsy and ablations tools and endoscopes. The steerable medical instrument has an outer and an inner tube where the inner tube is movable at the proximal end and fixed at the distal end.

Systems and methods for synthesis of nitric oxide

Systems and methods for producing nitric oxide (no) to be used in medical applications are provided. In some embodiments, systems and methods are provided for a no generator that is capable of generating a desired concentration of no to be provided to a respiratory system for inhalation by a patient..

Gas sensing apparatus

The present disclosure pertains to an apparatus configured to facilitate monitoring of gas in a therapeutic gas delivery system with a catalytic sensor. The gas delivery system comprises a pressure generator having an inlet and an outlet, and a gas delivery flow path configured to communicate the gas between the pressure generator and a subject.

Respiratory assistance device

Respiratory assistance device suitable for auto cpap respiratory therapy. The respiratory assistance device includes: a blower device including a blower configured to generate pressurized air; an operation device including an operation interface configured to control the blower; a wireless or wired communication arrangement configured to connect the blower device and the operation device; an attachment part configured to be attached to a head of a patient so as to supply the pressurized air to an airway of the patient; and an air tube through which the pressurized air is introduced into the attachment part from the blower device.

Medicament delivery device with vibration sensor

A button-activated medicament delivery device is presented having a housing arranged to house a medicament container, a vibration sensor configured to measure vibrations induced by the button-activated medicament delivery device during a medicament delivery, a button arranged to initiate medicament delivery from the medicament container, and to activate the vibration sensor when initiating the medicament delivery, and processing circuitry configured to obtain a vibration measurement from the vibration sensor and to compare the vibration measurement with a reference vibration measurement characteristic for the button-activated medicament delivery device during medicament delivery. The processing circuitry is configured to generate a time of measurement of the vibration measurement in case the vibration measurement matches the reference vibration measurement..

Rubidium elution system

Provided are 82sr/82rb elution systems that accept patient weight as a input function in order to determine an optimal quantity of radioactive rubidium-82 for delivery to a patient pursuant to an imaging scan. Also disclosed are systems that deliver a saline flush to remove residual 82rb from the system downstream of the generator, and preferably deliver the removed residual 82rb to the patient.

Device and generating a filtered pressure signal

A signal filtering device acquires one or more pressure signals that comprise first pulses originating from a first pulse generator associated with a fluid containing system and second pulses. The signal filtering device populates (504) signal vectors by signal segments in the pressure signal(s) and computes (505) principal components for the signal vectors by principal component analysis (pca).

Suction device having suction occlusion capability

The present disclosure relates generally to a suction device, for example, suitable for use in a medical procedure. The present disclosure relates more particularly to a suction device including a suction tube having a proximal end and a distal end.

Reversible peristaltic pump and other structures for reflux in eye surgery

Devices, systems, and methods for treatment of an eye alter aspiration flow from the eye in response to an occlusion of the aspiration conduit pathway. Where aspiration is drawn from the eye using a volumetric pump, the pump can be reversed so as to induce fluid reflux from the aspiration conduit pathway into the eye to help clear the occlusion.

Regenerated oxidized celulose based hemostatic materialcontaining antifibrolytic agents

In present invention oxidation method of viscon cellulose with no2 obtained h3po4/hno3 is defined liquid and gas media. Regenerated oxidise cellulose (reoc in shorten term) contain in —cooh yields are standardised as 18.6-20.1 for textile, 19.8-21.5% for powder samples.

Sterilization apparatus

A sterilization apparatus characterized in that the sterilization apparatus comprises a reactive oxygen species irradiation unit for irradiating a reactive oxygen species-containing gas which is a reaction product of plasma generated using an alternating current and a water-containing gas containing steam, the sterilization apparatus further containing an inlet unit for steam flow for supplying the water-containing gas heated to a temperature of from 50° to 300° c., wherein the reactive oxygen species-containing gas contains water in an amount equal to or greater than the amount of saturated steam. The sterilization apparatus of the present invention shows excellent sterilization activity, so that it can be suitably used in sterilization of containers for foodstuff, bottle caps sealing the openings of the containers, medical devices, foodstuff such as vegetables and meat, and the like..

Rna-based logic circuits with rna binding proteins, aptamers and small molecules

Engineered synthetic rna-based genetic circuits are provided that are regulated exclusively at the post-transcriptional level.. .

Adenovirus complex for gene delivery and gene therapy

The present invention relates to an adenovirus complex which can be utilized for gene delivery and gene therapy by targeting neurotensin receptors. The complex of the present invention has an excellent antitumor effect because of a high intracellular gene transfer efficiency and target specificity by neurotensin receptor-specific binding, has little hepatotoxicity and immunogenicity, forms a stable complex, has low immunogenicity, and thus has a low loss in blood even in an in vivo environment.

Personalized medicine therapeutic minicircle

Bispecific antibodies (bsabs) have emerged as a class of promising anti-cancer and anti-infection biological drugs. They are capable of killing target cells, either cancer cells or microbe-infected cells, at levels of nanograms per milliliter serum in vivo, about 1e+5 folds more powerful than regular antibodies.

Hnrnpa2b1-fam96a fusion protein and composition for diagnosing cancer

Result: a heterogeneous nuclear ribonucleoprotein a2/b1 (hnrnpa2b1)-family with sequence similarity 96 member a (fam96a) fusion protein, which is not expressed in a normal gastric tissue, but expressed only in a gastric cancer tissue, is identified.. .

Vaccines against streptococcus pneumoniae serotype 5

The present invention relates to well-defined synthetic saccharides of general formula (i) that are related to the repeating unit of streptococcus pneumoniae serotype 5 capsular polysaccharide and conjugates thereof. The conjugates and pharmaceutical compositions containing said conjugates are useful for prevention and/or treatment of diseases associated with streptococcus pneumoniae, and more specifically against diseases associated with streptococcus pneumoniae serotype 5.

Treatment of asthma with anti-tslp antibody

The present disclosure, relates, in general, to methods of treating asthma, including severe asthma and eosinophilic asthma, using an antibody specific for thymic stromal lymphopoietin (tslp).. .

Consensus/ancestral immunogens

The present invention relates, in general, to an immunogen and, in particular, to an immunogen for inducing antibodies that neutralizes a wide spectrum of hiv primary isolates and/or to an immunogen that induces a t cell immune response. The invention also relates to a method of inducing anti-hiv antibodies, and/or to a method of inducing a t cell immune response, using such an immunogen.

H3 influenza a virus

The invention provides an isolated h3 equine influenza a virus, as well as methods of preparing and using the virus, and genes or proteins thereof.. .

Immunogenic composition for preventing pneumococcal diseases and preparation method thereof

The invention provides an immunogenic composition for preventing pneumococcal diseases, comprising pspa-mrxi, pspa-ef5668, pspa-ef3296 and plyl460d, wherein the amount of each component is 10-100 μg/ml; the immunogenic composition is prepared by adding to aluminum adjuvant the corresponding dosages of the four stock solutions pspa-mrxi, pspa-ef5668, pspa-ef3296 and plyl460d, and mixing them homogeneously; the immunogenic composition can prevent infection and invasion by streptococcus pneumonia, covering more than 95% of the strains in clinic. The immunogenic composition has a wide application in the prevention of pneumonia, and is suitable for large-scale production in industry for its simple preparation method, low production cost, and short production cycle..

Chimeric ospa genes, proteins and methods of use thereof

The invention relates to the development of chimeric ospa molecules for use in a new lyme vaccine. More specifically, the chimeric ospa molecules comprise the proximal portion from one ospa serotype, together with the distal portion from another ospa serotype, while retaining antigenic properties of both of the parent polypeptides.

Novel treating macular degeneration using botulinum toxin-based pharmaceuticals

Formulations and methods of treatment are disclosed for prevention and/or treatment of visual loss from age-related macular degeneration. The disclosed formulations include botulinum neurotoxin (e.g., botulinum neurotoxin or a fragment thereof, either in pure form or with one or more peptide fragments and/or neurotoxin associated proteins.

Compositions comprising il-31 and uses thereof

A method for treating cancer and/or preventing or reducing metastasis or treating angiogenesis related disorders comprising the step of administering il-31 or peptide which is at least about 70%, homologous to the il-31 sequence as set forth in seq id no. 1..

Method to induce neovascular formation and tissue regeneration

The present invention relates, e.g., to a method for inducing arteriogenesis, lymphangiogenesis, vasculogenesis, or cardiomyogenesis, and/or for inducing mitosis or proliferation of a smooth muscle cell, a skeletal muscle cell, or a cardiomyocyte, comprising administering to a cell or tissue in need thereof a dose of a polynucleotide that encodes a vascular endothelial growth factor (vegf), or that encodes a polypeptide comprising an active site of the vegf. The coding sequence is operably linked to an expression control sequence; and the dose is sufficient to induce arteriogenesis, lymphangiogenesis, vasculogenesis, or cardiomyogenesis, and/or to induce mitosis or proliferation of a smooth muscle cell, a skeletal muscle cell, or a cardiomyocyte.

Method for modulating the expression of the srebp-1c, acc, and scd-1 proteins using longan pericarp extract

The present invention provides a method for reducing the expressions of the sterol regulatory element-binding protein 1c (srebp-1c), acetyl-coa carboxylase (acc), and stearoyl-coa desaturase 1 (scd-1), comprising administering to a subject a composition comprising an effective amount of a longan pericarp extract. The longan pericarp extract significantly inhibits lipogenesis, reduces the glutamic-pyruvic transaminase (gpt) index, and protects the liver..

Preparations of rosa laevigata fruit extracts and uses thereof for regulation of cd36, apoa1, and srb1

Provided is a method of a method of preparing a rosa laevigata fruit extract which regulates cd36, apoa1, and srb1, including extracting the fruit of rosa laevigata using water, alcohols, or mixtures of water and alcohols as solvents. Also provided is a method of regulating cd36, apoa1, and srb1, including administering to a subject a composition containing an effective amount of the rosa laevigata fruit extract.

Pharmaceutical composition or functional health food for preventing and treating metabolic diseases, containing water extract of pleurotus eryngii var. ferulae (pf.) as active ingredient

The present invention relates to a composition for preventing and treating metabolic disorders, containing a water extract of pleurotus eryngii var. Ferulea (pf) as an active ingredient, wherein the water extract of pleurotus eryngii var.

Methods of generating mesenchymal stem cells which secrete neurotrophic factors

A method of generating mscs which secrete neurotrophic factors (ntfs) comprising incubating a population of undifferentiated mesenchymal stem cells (mscs) in a differentiating medium comprising basic fibroblast growth factor (bfgf), platelet derived growth factor (pdgf), heregulin and camp.. .

Use of allogeneic interstitial vessel-layer cell and allogeneic mesenchymal progenitor cell for preventing or treating osteoarthritis

Provided are uses of allogeneic interstitial vessel-layer cells and allogeneic mesenchymal progenitor cells in the preparation of a pharmaceutical composition for preventing or treating osteoarthritis (oa). Also provided is a pharmaceutical composition containing the allogeneic interstitial vessel-layer cells and the allogeneic mesenchymal progenitor cells..

Crispr/cas-related methods and compositions for improving transplantation

Disclosed herein are compositions and methods for increasing the immunocompatibility of donor cells (e.g., hscs or t-cells) for transplantation to a recipient subject, as well as database schemes for use in the methods. The methods and compositions described herein result in the allele-specific modification of one or more immunogenicity genes (e.g., an hla gene) of a cell, resulting in cells that are suitable for transplantation into a recipient subject..

Method and compositions for cellular immunotherapy

The present invention provides methods and compositions to confer and/or augment immune responses mediated by cellular immunotherapy, such as by adoptively transferring genetically modified tumor specific cd8+ t cells in the presence of tumor-specific, subset specific genetically modified cd4+ t cells, wherein the cd4+ t cells confer and/or augment a cd8+ t cells ability to sustain anti-tumor reactivity and increase and/or maximize tumor-specific proliferation of the tumor-specific cd8+ t cells of interest. Pharmaceutical formulations produced by the method, and methods of using the same, are also described..

Treatment using chimeric receptor t cells incorporating optimized polyfunctional t cells

The disclosure provides methods of treating a malignancy comprising administering an effective dose of a chimeric receptor (e.g., car or tcr) genetically modified t cell immunotherapy. Some aspects of the disclosure relate to methods of determining an effective dose of a t cell immunotherapy comprising polyfunctional t cells prior to administration to the patient..

Use of trientine to deliver copper to ischemic tissue

Methods of ischemic tissue repair and regeneration through promoting tissue redistribution and reuse of copper by administering a composition comprising a copper chelating tetramine, such as trientine. Methods and compositions for increasing intracellular copper lever and/or inducing repair of an ischemic tissue in an individual.

Cobalt porphyrins for the treatment of blood-related disorders

The use of cobalt porphyrins for the manufacture of an agent for mobilizing bone marrow cells to peripheral blood, preferably used to treat congenital neutropenia, for the treatment and prevention of neutropenia caused by chemotherapy, radiotherapy and pharmacologically-induced neutropenia, for the treatment of acute myeloid leukemia, acute lymphocytic leukemia, myelodysplastic syndromes, and to increase the amount of circulating hematopoietic stem cells in peripheral blood for subsequent isolation in the process of apheresis and allogeneic or autologous transplantation.. .

Survivin-targeting anti-tumor agents and uses thereof

Methods for treating various cancers by administering one or more compounds that target the dimeric protein survivin are disclosed. Pharmaceutical compositions containing such compounds are also disclosed, along with general methods of identifying anti-cancer compounds that target oncogenic dimeric proteins.

Inhibitors of the fkbp51 protein from a high-throughput drug screen and methods of use

The subject invention concerns materials and methods for treating depression, stress disorders, such as ptsd, anxiety disorders, and/or a neurodegenerative disease or condition in a person or animal. In one embodiment, a person or animal in need of treatment is administered one or more compounds or drugs, or a composition comprising the one or more compounds or drugs, that inhibit fkbp51 activity or function.

Methods and compositions for treating neurodegenerative diseases

A method of treating a neurodegenerative disease is disclosed. The method comprises administering to the subject a therapeutically effective amount of a cxcr4 antagonist and lactate or/and zinc.

Compositions, dosage forms, and co-administration of an opioid agonist compound and an analgesic compound

The present invention relates generally to the co-administration of an opioid agonist compound and an analgesic compound. In addition, the invention relates to, among other things, dosage forms for co-administration of an opioid agonist compound and an analgesic compound, methods for administering an opioid agonist compound and an analgesic compound, compositions comprising an opioid agonist compound and an analgesic compound, dosage forms comprising an opioid agonist compound and an analgesic compound, and so on..

Therapeutic compounds

The present embodiments relate to substituted heterocyclic derivative therapeutic compounds, compositions comprising said compounds, and the use of said compounds and compositions for epigenetic regulation by inhibition of bromodomain-mediated recognition of acetyl lysine regions of proteins, such as histones. Said compositions and methods are useful for the treatment of diseases mediated by aberrant cell signalling, such as inflammatory disorders, cancer and neoplastic disease.

Treatment of age-related macular degeneration and other eye diseases with one or more therapeutic agents

The present disclosure provides therapeutic agents for the treatment of age-related macular degeneration (amd) and other eye disorders. One or more therapeutic agents can be used to treat any stages (including the early, intermediate and advance stages) of amd, and any phenotypes of amd, including geographic atrophy (including non-central ga and central ga) and neovascularization (including types 1, 2 and 3 nv).

Use of polymethoxylated flavones to ameliorate circadian rhythm disorders

Disclosed are methods comprising administering to a mammal suffering from, or at risk of suffering from, a clock-controlled disorder, such as metabolic syndrome or a constituent condition thereof, a composition comprising at least one polymethoxylated flavone. Disclosed are methods comprising administering a composition comprising at least one polymethoxylated flavone to a mammal suffering from or at risk of suffering from a sleep disorder; suffering from aging; and/or suffering from or at risk of suffering from a mood disorder.

Enhanced expression of mtor and inhibited expression of myostatin in skeletal muscle cells

Processes for increasing expression of a mtor gene or a mtor protein or decreasing expression of a mstn gene or a myostatin protein in a subject in need of such expression changes are provided. The processes include administering to the subject a composition including at least 0.5% type-a polymers by weight.

A fast acting orally disintegrating film for administration of local anesthesia

A fast acting orally disintegrating film (odf) for administration of local anesthetic for alleviating physical and psychological discomfort in the oral cavity during procedures such as dental procedures or for relieving pain generally such as toothaches. The odf comprises an active pharmaceutical ingredient such as lidocaine free base or a pharmaceutically acceptable salt thereof in a therapeutically acceptable amount such as about 24 mg, at least one primary hydrophilic film forming polymer, at least one secondary hydrophilic film forming polymer, wherein the ratio of the primary hydrophilic film forming polymer to the secondary hydrophilic film forming polymer is about 1:1 to about 20:1 by weight.

Systems and methods for making and using gel microspheres

The present invention generally relates to microfluidic droplets and, in particular, to multiple emulsion microfluidic droplets. In certain aspects, particles such as gel particles can be prepared in an aqueous carrier from aqueous droplets (or a non-aqueous carrier from non-aqueous droplets).

Decapeptide-12 modulation of sirtuin gene expression in epidermal keratinocyte progenitors

Recent reports detail the pleiotropic roles sirtuins play in repressing premature aging, delaying cellular senescence, enhancing longevity, and ameliorating a wide range of aging disorders. Herein, we report our findings on the potent sirtuin activator, decapeptide-12, and compare its performance to the well documented oxyresveratrol.

Auricular peripheral nerve field stimulator and operating same

An auricular peripheral nerve field stimulator includes an electrical stimulation device for generating electrical stimulation signals, at least one therapy electrode electrically coupled to the stimulation device and configured for percutaneous insertion into an auricle of a human ear near at least one neurovascular bundle, a processor, and a memory with software executable by the processor to (i) control the stimulation device to generate and deliver to the inserted at least one therapy electrode the stimulation signals at a selected frequency with one of a positive and a negative pulse relative to a reference to stimulate at least one auricular peripheral nerve field within the auricle, (ii) continually repeat (i) for a first duration, (iii) following expiration of the first duration, control the stimulation device to generate no stimulation signals for a second duration, and (iv) repeat (i) through (iii) with the stimulation signals having a modulated frequency.. .

Acoustic shock wave therapeutic methods

A method of modulating glandular secretions by administering acoustic shock waves to a reflexology zone or region has been discovered. In one preferred embodiment, a treatment method achieves one or more of a) modulating blood sugar levels, b) stimulating insulin production levels or c) normalizing a1c levels by using the step of administering acoustic shock waves to a reflexology zone or region.

Guiding people using acoustic signals

In order to guide a person along a path, audible acoustic signals are used, which are generated by signal generators arranged in an area. The person can orient themselves in the area using these acoustic signals.

Apparatuses, controlling exoskeletons

In some embodiments, apparatus and systems for controlling exoskeleton devices, and more particularly, smart crutches configured for sensing an environment and processing the sensed data to control the movement of exoskeleton devices over various types of surfaces are presented. In some embodiments, the smart crutches may comprise sensors configured to sense the state of the exoskeleton, the crutches and the surrounding environment, and to transmit such measurements to various components of the crutch and/or exoskeleton such as processing units, user interfaces, etc.

Method to promote health and function of the penis and vagina utilizing a combination of sound waves, electrical stimulation, light, and vacuum

This relates to a device that combines ultrasound energy, electrical energy, light, and vacuum to improve the general health function of the penis and the vagina. It is intended to be safe, easy to use way to increase and improve the vascular supply to the penis and vagina.

Interbody fusion implant

The present invention generally relates to an interbody fusion implant. Specifically, the present invention relates to an implant that incorporates a purposefully designed three-dimensional matrix that optimizes bony ingrowth, with such matrix then being overmolded with a material that provides structural support..

Expandable intervertebral implants and methods of installation thereof

Embodiments herein are generally directed to expandable spinal implants, systems, apparatuses, and components thereof that can be used in spinal fusion and/or stabilization procedures, as well as methods of installation. The expandable spinal implants may be configured for lateral insertion..

Expandable vertebral prosthesis

The present invention relates to an expandable prosthetic implant device for engagement between vertebrae generally comprising an inner member, outer member, and gear member positioned coaxial with respect to each other such that the inner and outer members are moveable relative to each other along an axis. The gear member is axially fixed to the outer member and freely rotatable with respect to the outer member and the gear member threadedly engages a threaded portion of the inner member to translate inner member along the axis.

Trial femoral prosthesis and its use

Embodiments of the present application relate generally to provisional orthopedic components, and more specifically relate to a trial system including a cam module and a trial femoral component that can be used during joint replacement surgery. The systems and methods of the present application aid a surgeon in the preparation of a patient's bone to receive a permanent implant by providing a system that can be used to guide preparatory box cuts, and that can then be completed with a cam module without removal from the patient's bone so that the same component can be used for the trialing process..

3-d printing of porous implants

Computer implemented methods of producing a porous implant are provided including obtaining a 3-d image of an intended tissue repair site; generating a 3-d digital model of the porous implant based on the 3-d image of the intended tissue repair site. The method also includes determining an implant material and an amount of a porogen to add to an implant material to obtain a desired porosity of the porous implant.

Papillary muscle position control devices, systems, and methods

Papillary muscle position control devices, systems, and methods are provided. A papillary muscle position control device generally includes a first anchor, a second anchor, and a support structure.

Three-dimensional medical implant for regeneration of soft tissue

The present disclosure relates to a three-dimensional, degradable medical implant for regeneration of soft tissue comprising a plurality of volume-building components (20) and a mesh component (22) which is substantially made of monofilament or multifilament fibers, wherein each volume-building component (20) is attached to at least one point on a surface of the mesh component (22), and wherein the projected surface area of each volume-building component (20), when projected on the surface of the mesh component (22), corresponds to a maximum of one tenth of the surface area of the mesh component.. .

Anti-parallax correction of stereoscopic surgical images

Methods and systems for anti-parallax correction of stereoscopic surgical images may employ a stereoscopic surgical microscope to generate overlay content as left and right digital images that are overlaid on respective left and right analog images from an objective field of view of the surgical microscope. The user may select a location-dependent feature in the overlay content and may select left or right for the anti-parallax correction..

Medical manipulator system

A medical manipulator system includes: a first manipulator configured to change a position of an imaging section that images a target portion in a body; a second manipulator configured to change a position of an end effector that treats the target portion; a display section configured to display images from the imaging section; an operation section configured to generate an operation command for operating the first manipulator or the second manipulator; and a control section configured to select one of a plurality of control modes and control the first manipulator or the second manipulator based on the operation command.. .

Automated steering a robotic endoscope

Systems and methods for automated steering control of a robotic endoscope, e.g., a colonoscope, are provided. The control system may comprise: a) a first image sensor configured to capture a first input data stream comprising a series of two or more images of a lumen; and b) one or more processors that are individually or collectively configured to generate a steering control output signal based on an analysis of data derived from the first input data stream using a machine learning architecture, wherein the steering control output signal adapts to changes in the data of the first input data stream in real time..

Medical manipulator system and image display method therefor

A medical manipulator system includes: an endoscope; a first manipulator equipped with a first treatment tool at a distal end thereof; a second manipulator equipped with a second treatment tool at a distal end thereof; a display for a user to view; and a controller configured to generate an image to be displayed on the display. The controller is configured to: acquire a first image taken by the endoscope, the first image contains the first treatment tool; and in response to determining that the second treatment tool does not exist in the first image: calculate a relative distance and a relative direction between the first treatment tool and the second treatment tool; generate a second image showing the relative distance and the relative direction between the first treatment tool and the second treatment tool; and send the first image and the second image to the display..

Fiducial marking for image-electromagnetic field registration

Methods and systems for placement of and/or placement planning for body surface electrodes are described. In some embodiments, body surface electrodes are used to generate intra-body electromagnetic fields sensed by intra-body probes for applications such as electrical field-guided catheter navigation and/or dielectric property-based tissue lesion assessment.

System and methods for positioning bone cut guide

Systems and methods for positioning a cut guide using navigation-based techniques are discussed. For example, a system for use in an orthopedic surgery on a target bone can comprise a cut guide adjustably positionable onto the target bone via two or more coupling receptacles created on the target bone.

System and methods for positioning bone cut guide

Systems and methods for positioning a cut guide using navigation-based techniques are discussed. For example, a system for use in an orthopedic surgery on a target bone can comprise a cut guide adjustably positionable onto the target bone via two or more coupling receptacles created on the target bone.

System and methods for positioning bone cut guide

Systems and methods for positioning a cut guide using navigation-based techniques are discussed. For example, a system for use in an orthopedic surgery on a target bone can comprise a cut guide adjustably positionable onto the target bone via two or more coupling receptacles created on the target bone.

System and fluorescence-based laser ablation

In an embodiment, an apparatus and method are described for ablating tissue in response to determining a fluorescence condition. An excitation light source may produce excitation light at a excitation wavelength of a fluorophore.

Electrosurgical instrument for radiating microwave energy and dispensing liquid at a treatment site

An electrosurgical device capable of both: (i) generating a radiative microwave field to perform either blood coagulation or sterilization, and (ii) dispensing a liquid to a target area, e.g. Adrenaline for the treatment of peptic ulcers.

Apparatus and percutaneously extending an existing spinal construct

Apparatus and devices for percutaneously extending an existing spinal construct ipsilaterally with an additional spinal construct in a patient are disclosed. The additional spinal construct comprises a rod connector that includes an elongate additional rod integrally attached thereto.

Orthopedic derotation devices and methods of installation thereof

Embodiments herein are generally directed to derotation systems, apparatuses, and components thereof that can be used in spinal derotation procedures, as well as methods of installation. The derotation systems may include a plurality of derotation towers and clamp members..

Elastic member clamps

The present application generally relates to orthopedic stabilization systems, and in particular, to systems including clamps. The clamps can be used in addition to or to replace hooks that grasp onto bone members, such as the lamina.

Robotically-controlled shaft based rotary drive systems for surgical instruments

A surgical instrument including an end effector that has a selectively reciprocatable implement movably supported therein. The implement is selectively advanceable in a distal direction upon application of a rotary actuation motion thereto and retractable in a proximal direction upon application of a rotary retraction motion thereto.

Contra retractor

A handheld surgical retractor device for manually effecting safe and certain contralateral displacement of a patient's incised tissue by a single surgical assistant during invasive surgery, while said assistant manually effects lateral displacement of the patient's incised tissue to create an operative field. The device includes a handle attached to a first bar for transmitting a compressive force to a second bar to generate a tensile force acting on a retractor blade, with minimum obscuration and obstruction of the operative field.

Ultrasonic ct apparatus and ultrasonic imaging method

Information relevant to a state of a tissue in a subject (state information) is provided with technology reducing the amount of memory and computation necessary at the time of extracting the information. An ultrasonic wave is transmitted towards a subject, a transmission wave transmitted through the subject or a reflection wave reflected on the subject is received.

Ultrasound diagnosis apparatus

An ultrasound diagnosis apparatus includes: a transmitter that outputs a drive signal to an ultrasound probe that transmits and receives ultrasound waves; a receiver that obtains a reception signal from the ultrasound probe; an image generator that generates ultrasound image data from the reception signal; a multiple-image-saved image data acquisition part that obtains multiple-image-saved image data containing a plurality of ultrasound images generated in the past within a single screen; an information acquisition part that obtains an image arrangement format of the plurality of ultrasound images of the obtained multiple-image-saved image data; and a display controller that performs comparison display of a comparison image among the plurality of ultrasound images of the multiple-image-saved image data and a current image based on the generated current ultrasound image data onto a single screen of the display part in accordance with the obtained image arrangement format.. .

Systems and methods for ultrasound elastography with continuous transducer vibration

Systems and methods for processing data acquired using ultrasound elastography, in which shear waves are generated in a subject using continuous vibration of an ultrasound transducer, are provided. The systems and methods described here can effectively remove motion artifacts associated with vibration of the ultrasound transducer, and can also remove the data sampling misalignment caused when a line-by-line imaging mode is used to acquire data, as is done by many conventional ultrasound scanners.

Ultrasonic diagnostic device and ultrasonic signal processing method

An ultrasonic diagnostic device including a push pulse generator 104 that sets a specific site in a subject and causes a plurality of transducers 101a to transmit a push pulse pp; a detection pulse generator 105 that causes multiple transmissions of a detection pulse pwi that converges outside and passes through a region of interest roi in the subject; a displacement detector 109 that generates an acoustic line signal for each observation point pij in the region of interest roi in order to detect displacement of tissue in the region of interest roi from an acoustic line signal frame data dsi sequence; and an elastic modulus calculator 110 that generates a wavefront frame data wfi sequence representing shear wave wavefront position, and calculates shear wave propagation speed and/or elastic modulus frame data emk in the region of interest roi based on the wavefront frame data wfi sequence.. .

Methods, systems and computer program products for single track location shear wave elasticity imaging

Methods, systems and computer program products for determining a mechanical parameter for a sample having a target region using shear wave displacement are provided. The method includes a) generating at least one shear wave with an excitation pulse in the target region at an excitation position; b) transmitting tracking pulses in a tracking region, at least a portion of which is outside the target region; c) receiving corresponding echo signals for the tracking pulses in the tracking region; d) repeating steps a through c for one or more additional excitation positions within the target region, wherein at least two of the excitation pulses overlap and the tracking region associated with each excitation position overlaps with the tracking region associated with at least one other excitation position; and e) determining at least one mechanical parameter of the target region based on at least one parameter of a shear wave displacement..

Ultrasound apparatus having switches

An ultrasound apparatus includes transducers, switches, a pulser, receiver, and processing unit, each transducer connected to the pulser and receiver via one switch and a single communications channel; the processing unit includes a memory and processor, is connected to the pulser and receiver, and identifies a first number that indicates a first aperture size, generates responses from the transducers, and processes the responses to produce image data; and the processor generates each response by selecting contiguous or non-contiguous transducers, the number being equal to the first number, for each switch connected to a selected transducer, sending a signal instructing the switch to connect the transducer to the communications channel, sending instructions to simultaneously fire selected transducers, with a pulse provided simultaneously to each selected transducer via the communications channel, and receiving a single response via the communications channel and receiver, which is the combination of outputs of the selected transducers.. .

Ultrasound imaging system having automatic image presentation

An ultrasound imaging system includes an interventional medical device having a first tracking element that generates tip location data based on an em locator field. An ultrasound probe has an ultrasound transducer mechanism and a second tracking element.

Ultrasound diagnostic apparatus and ultrasound probe

An ultrasound diagnostic apparatus includes: control section that switches a needle visibility priority mode in which ultrasound is not allowed to be transmitted from/received to transducer region including a central portion, but ultrasound is allowed to be transmitted from/received to transducer regions and excluding the central portion, and an image quality priority mode in which ultrasound is allowed to be transmitted from/received to transducer region; and an image generation section that generates needle visibility priority image data on the basis of reception signals in the needle visibility priority mode, and generates image quality priority image data on the basis of reception signals in the image quality priority mode.. .

Method and device for detecting viscoelastic parameter of viscoelastic medium

Disclosed is a method and device for detecting a viscoelastic parameter of a viscoelastic medium. The method comprises: applying a mechanical vibration at a single predetermined frequency to the viscoelastic medium to generate a shear wave in the viscoelastic medium (101); emitting ultrasonic waves to the viscoelastic medium, and receiving ultrasonic echo signals (102); acquiring maximum displacement data of the shear wave at various depths according to the ultrasonic echo signals (103), each of the maximum displacement data representing a maximum oscillation amplitude of the shear wave when the shear wave propagates to different depths in the viscoelastic medium; fitting each of the maximum displacement data to obtain a maximum displacement attenuation curve (104); and determining the viscoelastic parameter of the viscoelastic medium according to the maximum displacement attenuation curve (105).

Non-invasive assessment of anatomic vessels

Devices, systems, and methods of the present disclosure are directed to accurate and non-invasive assessments of anatomic vessels (e.g., the internal jugular vein (ijv)) of vertebrates. For example, a piezoelectric crystal may generate a signal and receive a pulse echo of the signal along an axis extending through the piezoelectric crystal and an anatomic vessel.

Rapid 3d cardiac parameter mapping

A method for generating a 3d map of a cardiac parameter in a region of a living heart, the method using single-plane fluoroscopic images and comprising: (a) placing a plurality of catheters each having one or more radio-opaque sensors into the region such that the locations of the sensors geometrically span the region; (b) capturing a first-view digitized 2d image of the region from a first fluoroscope positioned at a first angle; (c) identifying each of the plurality of sensors in the first-view image; (d) capturing a second-view digitized 2d image of the region from a second fluoroscope positioned at a second angle which is different from the first angle; (e) identifying each of the plurality of sensors in the second-view image; (f) associating each of the plurality of identified sensors in the second-view image with its corresponding identified sensor in the first-view image; (g) sensing and storing values of the cardiac parameter with each of the plurality of sensors; (h) determining the 3d location of each of the plurality of sensors from the first-view and second-view images using back-projection calculations; (i) associating each of the parameter values with its corresponding sensor location; (j) generating the parameter map from the first-view and second-view images; and (k) displaying the parameter map on a display device.. .

Non-invasive hemodynamic assessment via interrogation of biological tissue using a coherent light source

Systems and methods are disclosed for determining physiological information in a subject. The system includes: a light source positionable along a first location outside of the subject; a photo-sensitive detector positionable along a second location outside of the subject and configured to detect scattered light and generate a signal; a processor having a program and a memory, wherein the processor is operably coupled to the detector and configured to receive and store the signals generated over a period of time; wherein the processor is programmed to derive contrast metrics from the stored signals, calculate a waveform from the contrast metrics, decompose the waveform into basis functions and respective amplitudes, and compare the basis function amplitudes to determine the physiological information..

Electroanatomical mapping tools facilitated by activation waveforms

Systems and methods for facilitating display of cardiac information based on sensed electrical signals include a processing unit configured to receive a set of electrical signals; receive an indication of a measurement location corresponding to each electrical signal of the set of electrical signals; and generate an activation waveform corresponding to the set of electrical signals. Systems and methods disclosed herein may be configured to generate, based on the activation waveform, a representation of a cardiac electrical signal feature; and facilitate presentation, on a display device, of a cardiac map and the representation of the cardiac electrical signal feature..

Nose sensor

A patient monitor can noninvasively measure a physiological parameter using sensor data from a nose sensor configured to be secured to a nose of the patient. The nose sensor can include an emitter and a detector.

Transcutaneous medical device with variable stiffness

The present invention relates generally to variable stiffness transcutaneous medical devices including a distal portion designed to be more flexible than a proximal portion. The variable stiffness can be provided by a variable pitch in one or more wires of the device, a variable cross-section in one or more wires of the device, and/or a variable hardening and/or softening in one or more wires of the device..

Systems and methods for managing chronic disease using analyte and patient data

Devices, systems, and methods herein relate to managing a chronic condition such as diabetes. These systems and methods may obtain patient data from a plurality of devices, integrate the data for analysis of trends that may be presented to the patient and/or health care professional along with an actionable suggestion.

Methods for generating hybrid analyte level output, and devices and systems related thereto

Generally, methods, devices, and systems for generating a hybrid analyte level output are provided. The uncompensated analyte levels lag in time with respect to the lag-compensated analyte levels, and the hybrid analyte level output tracks between the uncompensated analyte levels and the lag-compensated analyte levels according to predetermined criteria..

Self-powered analyte sensor

Generally, embodiments of the invention relate to self-powered analyte determining devices (e.g., electrochemical analyte monitoring systems) that include a working electrode, a counter electrode, and an optional resistance value, where the working electrode includes analyte sensing components and the self-powered analyte determining device spontaneously passes a current directly proportional to analyte concentration in the absence of an external power source. Also provided are systems and methods of using the, for example electrochemical, analyte sensors in analyte monitoring..

Systems, devices, and methods for determining hearing ability and treating hearing loss

In one embodiment, an audio system can generate parametrically formulated noise signals. According to an embodiment, an audio system can both determine the hearing ability of an individual and increase the hearing ability of the individual by using parametrically formulated noise.

User identification by biometric monitoring device

Techniques for user identification by a biometric monitoring device are disclosed. In one aspect, a method of operating a biometric monitoring device may involve measuring a weight of a user in response to detecting that the user is standing on a platform, determining, based on sensor data generated by a sensor, a user parameter indicative of the user's identification, identifying one of a plurality of user profiles as corresponding to the user based on a comparison of the user parameter to parameter values and a comparison of the measured weight of the user to weight values, and updating the identified user profile based on at least one of the measured weight and the user parameter..

Detecting medical status and cognitive impairment utilizing ambient data

Devices for determining the likelihood that a user of a primary monitoring device (“pmd”) has developed a medical condition, generally comprising sensors coupled to the pmd, wherein the pmd detects changes to sensor readings over time, and wherein the changes indicate a change in the likelihood that a user of the pmd has developed a medical condition. In some embodiments, motion sensors are operably coupled to the pmd, and the pmd monitors and saves data relating to characteristics of motion detected, which are used to determine whether there has been a change in a likelihood that a user is undergoing a medical event.

Methods, systems, and detecting respiration phases

Methods and apparatus for detecting respiration phases are disclosed herein. An example apparatus for analyzing vibration signal data collected from a nasal bridge of a subject via a sensor to reduce errors in training an artificial neural network using the vibration signal data includes a feature extractor to identify feature coefficients of the vibration signal data.

Device, sysem and determining a respiratory feature of a subject based on a breathing gas

The present invention relates to a device for determining a respiratory feature of a subject based on a breathing gas generated by the subject when inhaling and/or exhaling, comprising an aerosol detection unit (12) for detecting an aerosol contained in a breathing gas generated by the subject, a deposition fraction measurement unit (14) for measuring a deposition fraction for the detected aerosol, wherein the deposition fraction indicates the fraction of aerosol deposited inside the subject over the total amount of the inhaled aerosol, and a respiratory feature determination unit (16) for determining the respiratory feature by relating the measured deposition fraction to a plurality of predetermined deposition fractions each corresponding to a different airway geometry of a respiratory tract.. .

Method and measuring bioimpedance

A method and an apparatus for measuring a bioimpedance are disclosed. The apparatus includes a first electrical signal generator configured to generate a first electrical signal to measure a bioimpedance of an object.

Catheter with multi-functional control handle having rotational mechanism

A catheter for use in a patient's heart, especially for mapping a tubular region of the heart, has a catheter body, a deflectable intermediate section and a distal mapping assembly that has a generally circular portion adapted to sit on or in a tubular region of the heart. A control handle of the catheter allows for single-handed manipulation of various control mechanisms that can deflect the intermediate section and contract the mapping assembly by means of a deflection control assembly and a rotational control assembly.

Annotation waveform

Systems and methods for processing cardiac information include a processing unit configured to receive a set of cardiac electrical signals; receive an indication of a measurement location corresponding to each of the set of electrical signals; and identify, for each electrical signal of the set of electrical signals, a deflection. The deflection includes a deviation from a signal baseline.

Orientation independent sensing, mapping, interface and analysis systems and methods

The disclosure relates generally to applications of orientation independent sensing (ois) and omnipolar mapping technology (ot) to various system, device and method embodiments as recited herein. Similarly, systems and methods suitable for supporting ois and ot systems and methods are disclosed.

Method and device for determining and presenting surface charge and dipole densities on cardiac walls

The invention discloses a method, a system, a computer program and a device for determining the surface charge and/or dipole densities on heart walls. Using the foregoing, a table of dipole densities ν(p′, t) and/or a table of surface charge densities ρ(p′, t) of a given heart chamber can be generated..

Annotation histogram

Systems and methods for facilitating processing of cardiac information based on sensed electrical signals include a processing unit configured to receive a set of electrical signals; receive an indication of a measurement location corresponding to each electrical signal of the set of electrical signals; and generate, based on at least one of an annotation waveform corresponding to each electrical signal of the set of electrical signals and a set of annotation mapping values, an annotation histogram.. .

Electronic apparatus and method capable of reducing or avoiding offset interference and accurately measuring physiological characteristics of user

A method for measuring physiologically characteristics of user includes: using at least one light emitting unit to emit light ray including first light component corresponding to first wavelength and second light component corresponding to second wavelength different from the first wavelength; using an image sensing circuit to sense and generate at least one physiologically characteristics measurement signal in response to the light ray; performing an offset calibration operation upon the physiologically characteristics measurement signal to generate at least one calibrated measurement signal; and, calculating the calibrated measurement signal to estimate a physiologically characteristics result.. .

System for characterization, diagnosis, and treatment of a health condition of a patient and methods of using same

A system integrating a hemodynamic parameter (hdp) monitoring system and a radiofrequency generator synchronized by a processing system is disclosed. The system is capable of identifying health condition-specific hdp variation values changes in a patient upon the exposure of low energy amplitude modulated electromagnetic fields frequencies (sfq).

Physiological measurement device using leds

A wearable device includes a measurement device adapted to be placed on a wrist or ear having a light source with leds to measure physiological parameters. The measurement device generates an optical beam having a near infrared wavelength between 700-2500 nanometers by modulating the leds, and lenses to deliver the beam to tissue, which reflects the beam to a receiver having spectral filters in front of spatially separated detectors coupled to analog to digital converters that generate at least two receiver outputs.

Light-based spectroscopy with improved signal-to-noise ratio

A measurement system includes a light source having semiconductor sources, a multiplexer, and one or more fused silica fibers configured to form an output optical beam having one or more optical wavelengths modulated at a modulation frequency. A light beam set-up includes a monochromator forming a filtered optical beam.

Characterizing life quality of a living entity via hyper-spectral imaging and analysis, and applications thereof

Methods and apparatuses for characterizing life quality of a living entity via hyper-spectral imaging and analysis, and applications thereof, such as managing life quality of a living entity. Includes acquiring hyper-spectral imaging data and information of: anatomical features of the living entity, and substances consumable by the living entity; generating and maintaining a living entity-specific database containing data and information about the living entity; processing acquired living entity anatomical feature and acquired living entity consumable substance hyper-spectral imaging data and information, and living entity data and information; using processed data and information to generate living entity life quality data and information characteristic of life quality of the living entity.

Optical scanning device, imaging device, and tof type analyzer

An object of the invention is to provide a technology for further improving scanning performance. Provided is an optical scanning device including: a scanning unit including an optical waveguide configured to guide incident light and emit the light from an emission end, and a vibration unit configured to generate a vibration and vibrate the emission end; and a signal transmission unit configured to transmit a signal to the scanning unit and cause the scanning unit to scan an object, characterized in that the scanning unit includes a first bonding and vibration attenuating unit configured to bond, with an elastic member, an end surface of the vibration unit closer to the emission end and the optical waveguide..

System and monitoring and determining a medical condition of a user

A system and method for monitoring and determining a medical condition of a user, via a communication device of the user is disclosed. The system and a method according to some embodiments, may comprise a memory and a processor, the processor may be configured to receive an audio signal related to a user's speech, and determine a progress of a disease of the user based on comparing the audio signal to a reference audio signal.

Image pickup system and image processing apparatus

An image pickup system includes a light source unit configured to perform illumination; an image pickup unit configured to output an image pickup signal; a pre-processing unit configured to generate a first image signal, a second image signal, and a third image signal, each corresponding to one field, and sequentially output the image signals; and a synchronization processing unit configured to selectively assign the image signals sequentially outputted to a first color channel, a second color channel, and a third color channel. The synchronization processing unit switches first assignment processing for assigning the first image signal to the first color channel and further assigning the second image signal to the second and third color channels and second assignment processing for assigning the first image signal to the first color channel and further assigning the third image signal to the second and third color channels..

Imageing device and endoscope

An imaging apparatus includes: a lens unit in which a plurality of optical elements including one or more wafer-level lenses and a spacer are laminated; an imaging element configured to receive light incident from the lens unit, perform photoelectric conversion on the light, and generate an image signal; and a moisture-proof member that is bent and arranged so as to come in contact with at least a part of side surfaces of the lens unit to prevent moisture from entering a gap between the optical element and the spacer and/or a gap between the optical elements.. .

Systems and methods for amplifying changes in a region of interest in a surgical environment

The present disclosure is directed to systems and methods for amplifying a region of interest in a surgical environment. The system includes a stereo endoscope having a first camera and a second camera configured to obtain one or more images of the surgical environment.

Vacuum cleaner

A vacuum cleaner having improved obstacle detection precision. The vacuum cleaner includes a main casing, driving wheels, control unit, cameras, an image generation part, and a discrimination part.

Surface cleaning head with leading roller

A surface cleaning head with a leading roller may be used to facilitate capturing of debris in the air flow into a suction conduit on the underside of the surface cleaning head. The leading roller is generally positioned adjacent to and in advance of the opening of the suction conduit.

Disposable toilet bowl scrub system

The present disclosure generally relates to a scrub head capable of use in a disposable toilet bowl cleaning system and to methods of making and using the scrub head. The present disclosure also generally relates to a disposable toilet bowl cleaning system and to methods of making and using the disposable toilet bowl cleaning system..

Device for molding a foodstuff

Provided herein is device and kit for molding a foodstuff, for example, a ground meat or a bread dough, to make a kabob. Generally, the separate component parts of the device are a container, a mold and a press which are removably engageable one with the other.

Cooking grill with hood lighting

A grill or bbq appliance that is generally intended for outdoor use has a pivoting hood disposed in hinged connection with a grill body, both of which are raised above a firebox that receives a food support grate. The hood may include overhanging lights configured to provide optimal lighting through a range of hood positions.

Cooking grill radiant tray

A radiant tray system may be positioned between a burner and a grate of a cooking device. The system may include ceramic tiles and a housing having generally planar walls configured to house the tiles therebetween.

Cooking grill with electrical component protection

A grill or bbq appliance that is generally intended for outdoor use has a pivoting hood disposed in hinged connection with a grill body, both of which are raised above a firebox that receives a food support grate. The hood may include various double wall configurations or cavities configured to protect wiring or electrical components such as lights or sensors..

Smoker or grill ash management system

A smoker or grill ash management system includes a fire pot, generally cylindrical in shape, with a top flame opening, a bottom discharge opening, and combustion air openings adjacent the top flame opening. A mesh floor is located in the fire pot near the bottom of the fire pot below the combustion air openings and proximate the discharge opening.

Cooking grill with ir burner

A grill or bbq appliance that is generally intended for outdoor use has a pivoting hood disposed in hinged connection with a grill body, both of which are raised above a firebox that receives a food support grate. A downward facing ir burner may be housed in an upper portion of the grill above the food support grate..

Cup

A cup generally includes a container body and a cap connected on the container body. The cap has a hollow transparent base defining a central through space and an annular channel around the central through space, a plurality of decorative objects located in the annular channel of the hollow transparent base, a sealing ring, and a top plate.

Comb

A comb includes a generally flat, planar body having a left side surface, a right side surface, a top edge, a handle end, and an opposite front end. A plurality of teeth is provided on the body, each tooth having a root secured to the comb body near the top edge and having an opposite free end, a first barb projecting in a first direction towards the handle end and being located approximately half a distance between the root and the free end, and a second barb projecting in a second direction opposite the first direction, and being located approximately half a distance between the first barb and the root..

Wearable construct with dynamic fluid display

A construct (10) is provided having an aesthetic form adapted to please a wearer and to be worn by the wearer. The construct provides a structure on which functional elements are integrated.

Portable electronic device with strap

The invention proposes a portable electronic device (100) having a housing (101) and a strap (107) that is mechanically attached to the housing. The housing encompasses electronic components and protects them from ambient influences.

Increased access footwear

An article of footwear providing easy donning and doffing through a heel region. A heel cup is pivotably coupled with the footwear to articulate between an open configuration allowing easier access to a foot-receiving cavity and a closed configuration enclosing a heel region of the footwear.

Helmet system and methods

One variation of a method for recording accidents includes: in a first mode, capturing a second video frame at a second time, storing the second video frame with a first sequence of video frames, captured over a buffer duration, in local memory in the helmet, removing a first video frame captured outside of the buffer duration from local memory, and rendering a subregion of the second video frame on a display arranged within the helmet; in response to detection of an accident involving the helmet, transitioning from the first mode into a second mode; in the second mode, capturing a second sequence of video frames, and storing the second sequence of video frames exceeding the buffer duration in local memory; and generating a video file from the first sequence of video frames and the second sequence of video frames stored in local memory.. .

Hairpiece having perimeter with pass-through openings

One hair addition has a net with a central portion, a perimeter portion encircling the central portion, an upper face, and a lower face. A polymer base having an outer boundary extends below the net lower face at the entire net perimeter portion.

Protection system and method

This disclosure provides a protective gear and system for cushioning an object against falling. The protective gear includes a housing conforming to a portion of the object, an airbag disposed in the housing, a detector configured to detect a motion of the object; and a controller configured to generate an actuating signal to deploy the airbag if the motion is over a threshold.

Garment for containing moisture compositions

A maternity or postpartum support-garment that includes at least one of a stretchable and/or compressive material, at least one generally cylindrical shaped upper portions, and at least one generally cylindrical shaped base portions is provided. The maternity or postpartum support garment may further include at least one ribbing sections located on at least one of the one or more generally cylindrical shaped upper portions or base portions.

Aerosol-generating article, aerosol-generating pellet, forming aerosol-generating pellets and aerosol-generating system comprising aerosol-generating pellets

The aerosol-generating article (9) comprises a casing (8) and a plurality of aerosol-generating particles (1) arranged in the casing. The aerosol-generating particles of the plurality of aerosol-generating particles comprise a core of susceptor material, which core of susceptor material is coated with aerosol-forming substrate.

Electronic vapour generating device

An electronic vapour generating device and cartridge for use therein is disclosed. The device comprises a housing defining a chamber for receiving a cartridge for holding a liquid for atomisation, and a power source for providing electrical power to an atomiser for atomising the liquid.

Cartridge and device for an aerosol-generating system

There is provided a cartridge for an aerosol-generating system, the cartridge including: a liquid storage container containing a liquid aerosol-forming substrate including at least one flavor object; an outlet; a filter disposed between the outlet and a portion of the liquid storage container including the at least one flavor object; and a liquid transport element, having a first part and a second part, movable from a first position to a second position, wherein in the first position the first part of the liquid transport element is external to the cartridge and adjacent the outlet, and in the second position the first part of the liquid transport element is internal to the cartridge and remote from the outlet.. .

Cartridge for an aerosol-generating system

There is provided a cartridge for an aerosol-generating system, including a housing configured to hold an aerosol-forming substrate and having an opening; and a heater assembly including at least one heater element fixed to the housing and extending across the opening of the housing, wherein the at least one heater element defines a plurality of apertures configured to allow fluid to pass through the at least one heater element, and wherein apertures of the plurality of apertures have different sizes. There is also provided an aerosol-generating system, including an aerosol-generating device and the cartridge.

Assembly drum and system and method using the same for the automated production of e-vapor devices

An assembler system for manufacturing vapor-generating articles may include a rotatable assembly drum including an outer face and a flute in the outer face. The flute is structured and arranged to hold a first section and a second section of the vapor-generating article.

Aerosol generating article having mouthpiece with surface formations and removable tipping wrapper portion

There is provided an aerosol generating article (10) comprising an aerosol generating substrate (12), a mouthpiece (14) in axial alignment with the aerosol generating substrate (12), and a tipping wrapper (20) wrapped around the mouthpiece (14) and at least a portion of the aerosol generating substrate (12). The mouthpiece (14) comprises a mouthpiece wrapper (30) circumscribing one or more mouthpiece segments (16).

Silver nanoparticle-enhanced photosensitizers

The present invention relates generally to compositions and methods of killing fungi using a surface plasmon coupled to a photosensitizer. A nanostructure (10) may include a silver nanoparticle core (12), a mesoporous silica shell (14), and a photosensitizer (16).

Cryopreservation method

Human biliary tree stem/progenitors (hbtscs) are being used for cell therapies of patients with liver cirrhosis. A cryopreservation method was established to optimize sourcing of hbtscs for these clinical programs and that comprises serum-free kubota's medium (km) supplemented with 10% dimethyl sulfoxide (dmso), ˜3% recombinant human albumin and 0.1% hyaluronans.

Pest control system and associated method

A pest monitoring system and associated method includes pest monitoring devices for placement at a site and generating a signal upon detection of a pest, and a pesticide dispensing unit including a reservoir housing a diluent and a pesticide module housing a pesticide. A computer device remotely disposed to the pest monitoring devices receives generated signals therefrom, analyzes environmental and historical factor data for the site to determine an amount and placement location of the pest monitoring devices for monitoring the site, and directs deployment of the pest control monitoring devices according to the analysis.

Angling event detecting and reporting apparatus

Provided herein is an angling event detecting and reporting apparatus to identify and report angling events, the apparatus comprising an angling event sensor adapted to be located in the reel of a fishing rod and generating data indicative of a parameter of the rod or reel when the rod or reel is in use. Additionally, there may be at least one processor in communication with the angling event sensor programmed to identify an angling event based on the data indicative of a parameter of the rod or reel..

Apparatus for monitoring angling events and identifying when a fish is on the line

Provided herein is an apparatus to identify angling events such as when a fish is on the line. The system includes an angling event sensing device with a sensor to generate data indicative of a fishing rod, reel or line and a processor to identify when a fish is on the line based on the data..

System for providing angling recommendations and data

Provided herein is a system to generate angling recommendations associated with detected angling events associated with a user's use of a fishing rod and reel. The system includes an angling event sensing device, a processor, a mobile device in communication with the processor or the angling event sensing device, and a recreation monitoring platform to receive the angling event and data from the user's angling event sensing device and a plurality of other angling event sensing devices and make a recommendation..

Genetically modified non-human animals and methods of use thereof

Genetically modified non-human animals expressing human sirpα and human il-15 from the non-human animal genome are provided. Also provided are methods for making non-human animals expressing human sirpα and human il-15 from the non-human animal genome, and methods for using non-human animals expressing human sirpα and human il-15 from the non-human animal genome.

Genetically modified rat models for severe combined immunodeficiency (scid)

This invention relates to the engineering of animal cells, preferably mammalian, more preferably rat, that are deficient due to the disruption of tumor suppressor gene(s) or gene product(s). In another aspect, the invention relates to genetically modified rats, as well as the descendants and ancestors of such animals, which are animal models of human cancer and methods of their use..

Transgenic non-human animal expressing human specific molecule and human fcy receptor family

It is an object of the present invention to provide a transgenic non-human animal, which can appropriately evaluate properties, pharmacological effects and safety of a molecular targeted substance or targeted drug to a human specific molecule, and to provide a method for producing the transgenic non-human animal, which comprises a gene encoding a human specific molecule and a gene encoding a human fcγ receptor family, both genes being introduced in the animal, thereby expressing the gene encoding a human specific molecule and the gene encoding a human fcγ receptor family.. .

System for thermal comfort of animals in a livestock farming enclosure

Disclosed is a system for thermal comfort of animal in a livestock farming enclosure, which includes: at least one comfort mattress which includes at least one resilient layer including a plurality of sealed cavities which are parallel to one another; a heat-transfer fluid, intended for filling the sealed cavities; a unit for generating a circulation of the heat-transfer fluid inside the sealed cavities; and optionally a unit for regulating the temperature of the heat-transfer fluid.. .

Genetic markers associated with drought tolerance in maize

The presently disclosed subject matter relates to methods and compositions for identifying, selecting, and/or producing drought tolerant maize plants or germplasm. Maize plants or germplasm that have been identified, selected, and/or produced by any of the methods of the presently disclosed subject matter are also provided..

Control system for a canopy

A method includes receiving a treatment temperature from a user device; positioning a tree within a treatment region of a canopy; flowing a fluid from a hot fluid generating system to the canopy; spraying the fluid from the hot fluid generating system into the treatment region of the canopy; and selectively enabling and disabling a fluid flow from the hot fluid generating system to the canopy to maintain the treatment temperature within the treatment region of the canopy.. .

Method for monitoring growth of plants and generating a plant grow schedule

One variation of method for monitoring growth of plants within a facility includes: aggregating global ambient data recorded by a suite of fixed sensors, arranged proximal a grow area within the facility, at a first frequency during a grow period; extracting interim outcomes of a set of plants, occupying a module in the grow area, from module-level images recorded by a mover at a second frequency less than the first frequency while interfacing with the module during the period of time; dispatching the mover to autonomously deliver the module to a transfer station; extracting interim outcomes of the set of plants from plant-level images recorded by the transfer station while sequentially transferring plants out of the module at the conclusion of the grow period; and deriving relationships between ambient conditions, interim outcomes, and final outcomes from a corpus of plant records associated with plants grown in the facility.. .

Crop cart loading system

A crop cart loading system for loading a crop. The crop cart loading system generally includes a hopper having a floor and a sidewall extending from the floor to an upper edge thereof.

Bulb planter

The bulb planter employs a pair of members which cooperate to form a generally cylindrical structure with a working end in a closed position. One member pivots to an open pivoted position wherein the members separate at the working ends.

Two-handled shovel

A utility apparatus includes an elongated shaft having a first end and a second end, a utility head affixed to the second end of the elongated shaft and a first handle affixed to the first end of the elongated shaft. The utility apparatus further includes a secondary shaft affixed to the elongated shaft along a middle third of the elongated shaft and extending rearwards generally toward the first handle.

Methods for growth and maturation of ovarian follicles

The present technology provides for methods for generation and isolation of granulosa cells and/or granulosa cell precursors from multi-potent cells, wherein the granulosa cells and/or granulosa cell precursors are useful in methods for growth and maturation of follicles or follicle-like structures. Additionally, the present technology also provides for methods of increasing steroidal hormones in a subject in need thereof..

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Xeno-free generation of tissue-specific progenitor cells

The invention relates to purified, tissue-specific progenitors, methods of making and using such tissue-specific progenitors.. .

Methods for engineering allogeneic t cell to increase their persistence and/or engraftment into patients

The present invention relates to methods for developing engineered immune cells such as t-cells for immunotherapy that have a higher potential of persistence and/or engraftment in host organism. In particular, this method involves an inactivation of at least one gene involved in self/non self recognition, combined with a step of contact with at least one non-endogenous immunosuppressive polypeptide.

Cell expansion

Embodiments described herein generally provide for expanding cells in a cell expansion system. The cells may be grown in a bioreactor, and the cells may be activated by an activator (e.g., a soluble activator complex).

Neural cell populations from primate pluripotent stem cells

This invention provides a system for efficiently producing differentiated cells from pluripotent cells, such as human embryonic stem cells. Rather than permitting the cells to form embryoid bodies according to established techniques, differentiation is effected directly in monolayer culture on a suitable solid surface.

Method of manufacturing and purifying exosomes from non-terminally differentiated cells

The present invention discloses a high volume manufacturing process for the production and purification of exosomes. In one embodiment, a hollow fiber perfusion reactor is used to expand stem cells.

Microdevice platform recapitulating hypoxic tissue microenvironments

Hypoxia plays a central role in cancer progression and resistance to therapy. A microdevice platform is engineered to recapitulate the intratumor oxygen gradients that drive the heterogeneous hypoxic landscapes in solid tumors.

Lateral circulator and agitator for pond cultivation

A lateral circulator for generating agitation or circulation in a cultivation pond is disclosed. The circulator comprises at least a drive pulley and a secondary pulley, both oriented vertically and placed in the pond separated from one another along the length of the pond.

Ionic liquid, lubricant, and magnetic recording medium

A lubricant including an ionic liquid wherein the ionic liquid includes a cation that is represented by general formula (a) below and is free from a fluorine atom, and an anion that is represented by general formula (x) below and is free from a fluorine atom,. .

Slow-burning log

The invention relates to warming, heating devices for warming and cooking, and it can be utilized in household, in the field, in camping and in any touristic events as a source of stand-alone flame for warming, cooking, as well as for illumination. A slow-burning log that is made of a solid-fuel material of a vegetable origin has upper, lower and side surfaces, at least two vertical through incisions that extend from the upper surface to the lower one and intersect with each other thereby forming a general through vertical hole that begins in a midsection of the upper surface.

Dairy manure waste fiber to energy process

A process for converting waste fibers to solid fuel is provided, including providing a supply of animal waste including the waste fibers in a predetermined quantity; washing the supply of animal waste for a predetermined washing period; dewatering the supply of animal waste by separating water from the waste fibers for a predetermined dewatering period; shedding the waste fibers for separating liquids from solids; compressing the dewatered and shed waste fibers to generate a plurality of briquettes; torrefying at least one of the plurality of briquettes in a torrefaction reactor using a heat source at a predetermined torrefying temperature for a predetermined torrefying period; removing the at least one of the plurality of briquettes from the reactor; and cooling the torrefaction reactor to reach a predetermined cooling temperature.. .

Integrated biofuels process configurations, employing a 2-stage bio-reforming reactor system, in which renewable carbon content of gasoline and diesel are optimized for value

A bio-reforming reactor receives biomass to generate chemical grade syngas for a coupled downstream train of any of 1) a methanol-synthesis-reactor train, 2) a methanol-to-gasoline reactor train, and 3) a high-temperature fischer-tropsch reactor train, that use this syngas derived from the biomass in the bio-reforming reactor. A renewable carbon content of the produced gasoline, jet fuel, and/or diesel derived from the coupled downstream trains of any of 1) the methanol-synthesis-reactor train, 2) the methanol-to-gasoline reactor train, or 3) the high-temperature fischer-tropsch reactor train are optimized for recovery of renewable carbon content to produce fuel products with 100% biogenic carbon content and/or fuel products with 50-100% biogenic carbon content.

Systems and methods for gasification of carbonaceous materials

Carbonaceous-containing material including biomass, municipal solid waste, and/or coal and/or contaminated soil, and/or other carbonaceous materials may be gasified at low temperatures utilizing a reactor designed to generate shockwaves in a supersonic gaseous vortex. Preprocessed waste may be introduced into the reactor.

Resid upgrading with reduced coke formation

Systems and methods are provided for improving the processing of heavy or challenged feeds in a refinery based on integrated use of deasphalting, coking, and hydroprocessing. An optional fluid catalytic cracking unit can be included in the integrated system to allow for further improvements.

Flexible options for utilizing naphtha from a low temperature fischer-tropsch process in a plant converting biomass to syncrude or transportation fuels

A bio-reforming reactor receives biomass to generate chemical grade syngas for a coupled downstream train of a low-temperature fischer-tropsch reactor train that uses this syngas derived from the biomass in the bio-reforming reactor. A renewable carbon content of the produced gasoline, jet fuel, and/or diesel derived from the coupled downstream train the low-temperature fischer-tropsch reactor train are optimized for recovery of renewable carbon content to produce fuel products with 100% biogenic carbon content and/or fuel products with 50-100% biogenic carbon content.

Multi-purpose application of the second stage of a 2-stage bio-reforming reactor system for reforming bio-syngas, natural gas and process recycle streams

Multiple stages of reactors form a bio-reforming reactor that generates chemical grade bio-syngas for any of 1) a methanol synthesis reactor, 2) a methanol-to-gasoline reactor train, 3) a high temperature fischer-tropsch reactor train, and 4) any combination of these three that use the chemical grade bio-syngas derived from biomass fed into the bio-reforming reactor. A tubular chemical reactor of a second stage has inputs configured to receive chemical feedstock from at least two sources, i) the raw syngas from the reactor output of the first stage via a cyclone, and ii) purge gas containing renewable carbon-based gases that are recycled back via a recycle loop as a chemical feedstock from any of 1) the downstream methanol-synthesis-reactor train, 2) the downstream methanol-to-gasoline reactor train, or 3) purge gas from both trains.

Flexible pyrolysis system and method

Examples of a flexible pyrolysis system are provided that include at least one reaction chamber capable of pyrolyzing a combination of coal in a supercritical carbon dioxide (co2) atmosphere. The system includes a recuperating and condensing circuit that removes dissolved pyrolysis products from the supercritical co2 atmosphere and then recovers co2 for reuse in the reaction chamber.

System and rapid pyrolysis of coal

The present invention provides a system and a method for rapid pyrolysis of coal. The system comprises: a rapid pyrolysis reactor, which comprises: a reactor body defining a reaction space that forms a dispersion region, a pyrolysis region, and a discharge region from top to bottom; said dispersion region comprises: a material distributor; a coal inlet arranged above the material distributor; a material distribution gas inlet connected to the material distributor; said pyrolysis region comprises: multilayer regenerative radiant tubes, which are distributed at an interval in the height direction of the reactor body in the pyrolysis region, and each layer of regenerative radiant tubes consists of a plurality of regenerative radiant tubes distributed at an interval in the horizontal direction; said discharge region comprises: a semi-coke outlet; a plurality of pyrolysis gas outlets, which are arranged in the dispersion region and/or the pyrolysis region respectively; a slag cooler connected to the semi-coke outlet, and a cooling device connected to the pyrolysis gas outlet..

Spirofluorene derivatives and organic electroluminescent devices

The present disclosure provides spirofluorene derivatives and organic electroluminescent devices comprising the spirofluorene derivatives as a host material. The spirofluorene derivative is represented by general formula i.

Acrylic-based flexible assembly layer

The present invention is an assembly layer for a flexible device. The assembly layer is derived from precursors that include an alkyl(meth)acrylate ester having 1 to 24 carbon atoms in the alkyl group and a free-radical generating initiator.

Double-sided adhesive tape, electronic instrument provided with double-sided adhesive tape, disassembly structure provided with double-sided adhesive tape, and adhered structure

Provided is an adhesion technology that can separate adherends with their recycling as a premise while meeting their reliability guarantee temperature conditions. A double-sided, pressure-sensitive adhesive tape includes a pair of pressure-sensitive adhesive layers and an electrically-conductive heat generating layer disposed between the paired pressure-sensitive adhesive layers.

Halogen-free decorative homogeneous surface coverings

Halogen-free decorative surface covering compositions comprising a polymer blend, the polymer blend comprising: a) at least one thermoplastic elastomer, the thermoplastic elastomer being a block copolymer comprising hard and soft sequences, wherein the hard sequence is a (co)polymer of one or more vinyl aromatic monomer(s) and wherein the soft sequence is a (co)polymer of one or more alkylene(s) or of a mixture of one or more alkylene(s) and one or more vinylaromatic monomers; b) at least one thermoplastic polyurethane.. .

Rubber composition and tire

A rubber composition and a tire that can ensure the balance between the vulcanization speed and the foaming speed are provided. A rubber composition comprises: a diene-based rubber component; a foaming agent generating carbon dioxide; a fatty acid metal salt; and urea, wherein a content of the foaming agent is 0.1 parts to 20 parts by mass with respect to 100 parts by mass the diene-based rubber component, a total content of the fatty acid metal salt and the urea is 0.1 parts to 20 parts by mass with respect to 100 parts by mass the diene-based rubber component, and a mass ratio of the fatty acid metal salt and the urea is 1:0.5 to 1:3.9..

Fast cure epoxy composition for use in high throughput manufacturing processes

An epoxy resin composition having a first epoxy resin component containing an oxazolidone; a second epoxy resin component; a latent hardener comprising dicyandiamide particles having a particle distribution in which at least 35% of the dicyandiamide particles have a particle size of less than 2 microns; and an epoxy soluble latent catalyst is provided. It has been found that the combination of the epoxy components, a latent hardener having dicyandiamide particles in which at least 35% of the dicyandiamide particles have a particle size of less than 2 microns, and an epoxy soluble latent catalyst provides an epoxy resin composition that provides a more homogeneous infusion of the resin into a fibrous material for forming a prepreg.

Process for the preparation of (co)polymers of conjugated dienes in the presence of a catalytic system comprising a vanadium bis-imine complex

Process for the preparation of (co) polymers of conjugated dienes comprising polymerizing at least one conjugated diene in the presence of a catalytic system comprising at least one vanadium bis-imine complex having the general formula (i): wherein: m is 0 or 1; z represents a —cr5r6 group wherein r5 and r6, equal to or different from each other, represent a hydrogen atom; or a c1-c20 alkyl group, preferably c1-c15, linear or branched; or a bivalent aromatic group optionally substituted; r1 and r2 equal to or different from each other, represent a hydrogen atom; or they are selected from c1-c20 alkyl groups, preferably c1-c15, linear or branched, optionally halogenated, cycloalkyl groups optionally substituted; or r1 and r2, may be optionally bound each other so as to form, together with the other atoms which they are bound to, a cycle containing from 4 to 6 carbon atoms, saturated, unsaturated, or aromatic, optionally substituted by c1-c20 alkyl groups, preferably c1-c15, linear or branched, said cycle optionally containing heteroatoms such as, for example, oxygen, sulfur, nitrogen, silicon, phosphorus, selenium; r3 and r4, equal to or different from each other, represent a hydrogen atom; or they are selected from c1-c20 alkyl groups, preferably c1-c15, linear or branched, optionally halogenated, cycloalkyl groups optionally substituted, aryl groups optionally substituted; or r2 and r4, may be optionally bound each other so as to form, together with the other atoms which they are bound to, a cycle containing from 3 to 6 carbon atoms, saturated, unsaturated, or aromatic, optionally substituted by c1-c20 alkyl groups, preferably c1-c15, linear or branched, said cycle optionally containing other heteroatoms such as, for example, oxygen, sulfur, nitrogen, silicon, phosphorus, selenium; or r1 and r3, may be optionally bound each other so as to form, together with other atoms which they are bound to, a cycle containing from 3 to 6 carbon atoms, saturated, unsaturated, or aromatic, optionally substituted by c1-c20 alkyl groups, preferably c1-c1, linear or branched, said cycle optionally containing other heteroatoms such as oxygen, sulfur, nitrogen, silicon, phosphorus, selenium; x1, x2 and x3, equal to or different from each other, represent a halogen atom such as, for example, chlorine, bromine, iodine, preferably chlorine; or they are selected from c1-c20 alkyl groups, preferably c1-c15, linear or branched, —ocor7 groups or —or7 groups wherein r7 is selected from c1-c20 alkyl groups, preferably c1-c15, linear or branched; y is selected from ethers such as, for example, diethylether, tetrahydrofuran (thf), dimethoxyethane, preferably is tetrahydrofuran (thf); n is 0 or 1.. .

Recombinant bi-specific polypeptide for coordinately activating tumor-reactive t-cells and neutralizing immune suppression

The present invention relates generally to the field of generating fusion proteins to be used in cancer therapy, and more specifically, a bispecific t-cell engager recombinant polypeptide comprising an antibody, fragment thereof, or single chain variable fragment that binds to cd3 of a t-cell antigen receptor and an antibody, fragment thereof, or single chain variable fragment that binds to programmed death ligand 1 (pdl1) on a cancerous tumor cell to counteract the immune tolerance of cancer cells.. .

Anti-tie2 antibodies and uses thereof

The present invention provides antibodies that bind to tie2 and methods of using same. According to certain embodiments of the invention, the antibodies are fully human antibodies that bind to human tie2 and block the interaction between tie2 and one or more tie2 ligands such as angiopoietin 1 (ang1), angiopoietin 2 (ang2), angiopoietin 3 (ang3) and/or angiopoietin 4 (ang4).

Anti-cgrp/anti-il-23 bispecific antibodies and uses thereof

Bispecific antibodies are provided that bind calcitonin gene related peptide (cgrp) and interleukin-23 (il-23) and are characterized as having high affinity and strong simultaneous neutralizing properties to both cgrp and il-23. The bispecific antibodies of the invention are useful for treating various autoimmune diseases including inflammatory bowel disease, such as crohn's disease and ulcerative colitis, psoriatic arthritis (psa) and ankylosing spondylitis (as)..

Pesticidal genes and methods of use

Compositions having pesticidal activity and methods for their use are provided. Compositions include isolated and recombinant polypeptide sequences having pesticidal activity, recombinant and synthetic nucleic acid molecules encoding the pesticidal polypeptides, dna constructs comprising the nucleic acid molecules, vectors comprising the nucleic acid molecules, host cells comprising the vectors, and antibodies to the pesticidal polypeptides.

Alkyne compounds for treatment of complement mediated disorders

Compounds, methods of use, and processes for making inhibitors of complement factor d comprising formula i, or a pharmaceutically acceptable salt or composition thereof, wherein r12 or r13 on the a group is an alkyne (r32) are provided. The inhibitors described herein target factor d and inhibit or regulate the complement cascade at an early and essential point in the alternative complement pathway, and reduce factor d's ability to modulate the classical and lectin complement pathways.

Alkyne compounds for treatment of complement mediated disorders

Compounds, methods of use, and processes for making inhibitors of complement factor d comprising formula i, or a pharmaceutically acceptable salt or composition thereof, wherein r12 or r13 on the a group is an alkyne (r32) are provided. The inhibitors described herein target factor d and inhibit or regulate the complement cascade at an early and essential point in the alternative complement pathway, and reduce factor d's ability to modulate the classical and lectin complement pathways.

Pantothenate derivatives for the treatment of neurological disorders

Or a pharmaceutically acceptable salt thereof, wherein r, r′, r″, x and n are as defined herein are provided. Methods comprising use of such compounds for the treatment of neurologic disorders, such as pantothenate kinase-associated neurodegeneration, and pharmaceutical compositions containing such compounds, and their use in treatment of neurologic disorders are also provided..

Total synthesis of glucosepane and compounds obtained therefrom

Glucosepane is a structurally complex protein post-translational modification (ptm) believed to exist in all living organisms. Research in humans suggests that glucosepane plays a critical role in the pathophysiology of both diabetes and human aging; yet comprehensive biological investigations of this ‘metabolite have been’ greatly hindered by a scarcity of chemically homogeneous material available for study.

Novel compositions, uses and methods for making them

Generally, the present invention provides novel quinolone compounds and pharmaceutical composition thereof which may inhibit cell proliferation and/or induce cell apoptosis. The present invention also provides methods of preparing such compounds and compositions, and methods of making and using the same..

Acrylic acid derivative, preparation method and use in medicine thereof

The present invention relates to an acrylic acid derivative as shown in general formula (i), a stereoisomer, tautomer or pharmaceutically acceptable salt thereof, the preparation method thereof, a pharmaceutical composition containing same, and the use thereof as therapeutic agents, in particular as selective estrogen receptor degraders (serd), wherein the substituents of general formula (i) are the same as those defined in the description.. .

Aryl and heteroaryl-fused tetrahydro-1,4-oxazepine amides as somatostatin receptor subtype 4 (sstr4) agonists

The invention relates to aryl and heteroaryl-fused tetrahydro-1,4-oxazepine amide derivatives of general formula (1), which are agonists of somatostatin receptor subtype 4 (sstr4), useful for preventing or treating medical disorders related to sstr4. In addition, the invention relates processes for manufacture of the compounds according to the invention..

Oxidation process to produce a purified carboxylic acid product via solvent displacement and post oxidation

Disclosed is a process to produce a dry purified carboxylic acid product comprising furan-2,5-dicarboxylic acid (fdca). The process comprises oxidizing at least one oxidizable compound selected from the following group: 5-(hydroxymethyl)furfural (5-hmf), 5-hmf esters (5-r(co)och2-furfural where r=alkyl, cycloalkyl and aryl), 5-hmf ethers (5-r′och2-furfural, where r′=alkyl, cycloalkyl and aryl), 5-alkyl furfurals (5-r″-furfural, where r″=alkyl, cycloalkyl and aryl), mixed feed-stocks of 5-hmf and 5-hmf esters and mixed feed-stocks of 5-hmf and 5-hmf ethers and mixed feed-stocks of 5-hmf and 5-alkyl furfurals to generate a crude carboxylic acid slurry comprising fdca, removing impurities from a crude carboxylic acid slurry in a liquid displacement zone to form a low impurity slurry stream..

Monocarboxylate transport modulators and uses thereof

The invention generally relates to the field of monocarboxylate transport modulators, e.g., monocarboxylate transport inhibitors, and more particularly to new substituted-quinolone compounds, the synthesis and use of these compounds and their pharmaceutical compositions, e.g., in treating, modulating, forestalling and/or reducing physiological conditions associated with monocarboxylate transport activity such as in treating cancer and other neoplastic disorders, inflammatory diseases, disorders of abnormal tissue growth and fibrosis including cardiomyopathy, obesity, diabetes, cardiovascular diseases, tissue and organ transplant rejection, and malaria.. .

Kdm4 inhibitors

The present disclosure relates generally to compounds and methods for inhibiting the enzymatic activity of lysine demethylase 4 (kdm4) and treating cancer. Provided herein are substituted pyridine derivative compounds and pharmaceutical compositions comprising said compounds.

Urea derivative or pharmacologically acceptable salt thereof

The present invention relates to a compound represented by the general formula (i) or a pharmacologically acceptable salt thereof. The present invention also relates to a pharmaceutical composition containing the compound represented by the general formula (i) or a pharmacologically acceptable salt thereof..

Crystalline solid forms of the acetate salt of (1s,3s,4r)-4-((3as,4r,5s,7as)-4-(aminomethyl)-7a-methyl-1-methyleneoctahydro-1h-inden-5-yl)-3-(hydroxymethyl)-4-methylcyclohexanol

The present invention is generally directed to methods of using novel crystalline forms of the acetate salt of (1s,3s,4r)-4-((3as,4r,5s,7as)-4-(aminomethyl)-7a-methyl-1-methyleneoctahydro-1h-inden-5-yl)-3-(hydroxymethyl)-4-methylcyclohexanol and pharmaceutical compositions comprising same.. .

Methods for producing alkyl hydroxyalkanoates

Methods and systems for producing alkyl hydroxyalkanoates from hydroxycarboxylic acid recovery bottoms. The methods generally comprise the steps of obtaining a hydroxycarboxylic acid recovery bottom, adding a mono-alcohol to the hydroxycarboxylic acid recovery bottom to obtain a first mixture, heating the first mixture, optionally in the presence of a catalyst to form a reaction product, distilling the reaction product, and recovering an alkyl hydroxyalkanoate fraction..

Compositions of polyhydroxylated benzophenones and methods of treatment of neurodegenerative disorders

The present invention relates to polyhydroxylated benzophenone compounds useful in the treatment of neurodegenerative, neurological, psychiatric, and cognitive diseases, in particular those associated with a deficiency in hdac1 deacetylase activity.. .

Heterogeneous catalysts for the oxidative dehydrogenation of alkanes or oxidative coupling of methane

Improved methods of oxidative dehydrogenation (odh) of short chain alkanes or ethylbenzene to the corresponding olefins, and improved methods of oxidative coupling of methane (ocm) to ethylene and/or ethane, are disclosed. The disclosed methods use boron- or nitride-containing catalysts, and result in improved selectivity and/or byproduct profiles than methods using conventional odh or ocm catalysts..

Target tiles for an autothermal reformation/secondary reformation unit

A corrosion resistant refractory ceramic hexagonal target tile body for use covering a catalyst, including a generally flat hexagonal portion and a plurality of generally right circular cylindrical aperture portions extending therethrough, wherein the hexagonal tile body has a thickness of about 89 mm and a width of about 42 cm and is 13 percent yttria fully stabilized ysz. Each respective aperture has a diameter of about 19 mm..

Spherical bed topping/hold-down media for an autothermal reformation/secondary reformation unit

A generally spherical high strength ceramic body for use in an atr and/or sr unit covering a catalyst media bed. The ceramic body is a fully stabilized ysz composite composition having at least about 13% yttria ysz, and more typically from about 12% to about 20% yttria ysz, with a porosity of less than 20 percent and a diameter of at least 25 mm and, more typically, selected from the group comprising 25 mm, 50 mm, 76 mm and 100 mm..

Thermal barrier system with thin dense columnar tbc layer and methods of forming the same

A coating system disposed on a surface of a substrate is provided. The coating system may include a bond coating layer on the surface of the substrate, a dense tbc layer on the bond coating layer, and a columnar tbc layer on the dense tbc layer, with the columnar tbc layer defines a plurality of elongated surface-connected voids.

Ultrasonic near field hot glass transportation and forming

A system for levitating a softened, viscous or viscoelastic material by near field acoustic levitation. The system includes a support structure having a rigid surface, and a vibration generator operatively connected to the rigid surface.

Blue-oxygen oral care machine

Disclosed herein is an oral care machine including: a tank for storing water; an ozone generator for generating ozone, the ozone generator mounted in the tank, wherein generated ozone mixes with water stored in the tank; a processing cartridge for treating exhaust gas of ozone generated by the machine when ozone is mixed with water, the processing cartridge mounted on the tank; a water pump for transporting treated water; and a handle for delivering the treated water to a desired location.. .

Integrated system for supplying clean water and clean energy to the mining industry

Embodiments of this invention provide an integrated system for processing ore feedstock and ro treatment utilizing the principals of pumped storage hydroelectric technology including the use of an upper reservoir and lower reservoir. The integrated system includes a first subsystem that generates waste associated with processing the ore feedstock.

Integrated system for generating, storing and dispensing clean energy and desalinating water

Embodiments of this invention provide an integrated system for clean energy generation and storage and ro desalination. The integrated system includes a first subsystem that stores hydraulic energy.

Solar energy harvesting and reversible hydrogen storage methods and systems

The present disclosure relates to a reversible hydrogen transfer process and storage system using visible light to photocatalytically generate hydrogen from compounds comprising saturated or partially saturated carbocyclic residue and catalytically hydrogenate compounds comprising at least one carbocyclic aromatic residue.. .

Optical scanner module and optical scanner control apparatus

The present invention is to provide an optical scanner module capable of reducing cross-talk generated between a sensor interconnect and a drive interconnect. An optical scanner module, includes an optical scanner apparatus that scans incident light by oscillating a mirror; and a package on which the optical scanner apparatus is mounted, wherein the optical scanner apparatus includes a displacement sensor that detects an oscillation angle of the mirror, wherein a sensor interconnect (ps) connected to the displacement sensor and a drive interconnect through which a drive signal for oscillating the mirror passes are respectively drawn from the optical scanner apparatus into the package, wherein interconnect layers (l1, l2) in which the sensor interconnect and the drive interconnect (pd) are formed are stacked, wherein the sensor interconnect and the drive interconnect are placed not to overlap in a plan view of the interconnect layers, and wherein a gnd interconnect (pg) is provided between the sensor interconnect and the drive interconnect that are adjacent in a same interconnect layer..

Portable hoisting apparatus

A portable hoisting apparatus is disclosed which, in general, includes a base, multiple legs, and a winch. The legs pivotally connect to the base.

Elevator system including a protective hoistway liner assembly

An illustrative example elevator system includes a hoistway that establishes a vertical pathway. The hoistway has an interior border established by a plurality of stationary boundaries that each have a height aligned with a vertical length of the hoistway.

Apparatus of feeding workpieces with a mesh drum

The present invention provides an apparatus of feeding workpieces, capable of preventing generated contaminants from adhering workpieces and improving stabilization in a discharge rate of the workpieces while having advantage of the drum type. The apparatus has a mesh drum, a rotary drive and an angle adjuster.

Automated warehouse improvements

This document generally describes warehousing systems that can, in certain instances, improve the efficiency of warehousing operations and improve utilization of available space in a warehousing facility. The warehousing system may be implemented in an automated warehouse, such as an automated cold-storage facility, that uses programmable equipment to automate tasks associated with warehousing operations, such as transporting inbound storage items to specified storage positions of storage racks in the warehouse and removing outbound storage items from storage so that they may be loaded onto trucks for delivery away from the warehouse..

Drum support tray

A support tray configured to support at least two different diameter cylindrical containers. The support tray includes a generally planar body with opposed support surfaces.

Method and automatically packaging and dispensing food products

A food product gathering and dispensing system is disclosed. The food product is generally a flat disc shaped article dispensed onto a consumable strip of food product conveyer material.

Torque generation system, attitude control system for spacecraft, and relative position and velocity control system for spacecraft

A torque generation system includes: a plurality of solar array panels and/or solar array panel divisions; and a torque controller configured to control an electricity generation ratio of each of the plurality of solar array panels and/or solar array panel divisions to generate torque.. .

System for inerting and generating an inerting gas in an aircraft, operating without collecting outside air

An inerting system for aircraft including a gas circuit with successively at least one air inlet, a compressor and an air separation module. The air separation module includes an outlet for oxygen-enriched gas and an outlet for inerting gas.

Systems for generating auxiliary electrical power for jet aircraft propulsion systems

An aircraft jet propulsion system is disclosed. The aircraft jet propulsion system may comprise a thermoelectric generator array (“teg” array) coupled to a portion of the aircraft jet propulsion system, wherein the teg array converts heat energy to electrical energy, and supplies power to the aircraft jet propulsion system, wherein the electrical energy is supplied to a power supply.

Closed or semi-closed loop onboard ceramic oxygen generation system

An onboard rebreathing loop system resident on an aircraft for providing oxygen to aircraft personnel includes a ceramic oxygen generating system (cogs) module configured to receive an inlet air and output a high purity oxygen (o2) gas into a breathing loop and a carbon dioxide (co2) scrubber module configured to receive exhaled air from the aircraft personnel and output a co2-scrubbed air into the breathing loop. The high purity o2 gas and co2-scrubbed air are mixed to form a mixed gas having a partial pressure of o2 suitable for breathing by the aircraft personnel.

Autonomously guiding vehicles through orifices

This document generally describes a safe-passage guidance strategy developed in a relative velocity framework to enable a generic aerial robot execute a precision three-dimensional maneuver through a narrow orifice in a wall. The relative sizes of the robot and the orifice can be such that the orifice is only slightly larger than the robot.

Flight management system for flying objects

A flight management system that manages flight conditions of a plurality of flying objects and that causes the flying objects to work together in a coordinated manner to accomplish a purpose. The flight management system includes a flight management apparatus that receives instruction information for giving an instruction to flying objects, that registers a job based on performance information and status information of the flying objects, and that based on the job, gives a motion instruction to one or more flying objects.

High speed multi-rotor vertical takeoff and landing aircraft

This disclosure is generally directed to a high speed vertical takeoff and landing (vtol) aircraft that includes fixed wing flight capabilities. The high speed vtol aircraft may include at least two thrust producing rotors located equidistant from a longitudinal axis of the aircraft on a main wing, and at least two thrust producing rotors located equidistant from a longitudinal axis of the aircraft on a vertical wing.

Two-axis gimbal mounted propulsion systems for aircraft

A propulsion assembly for an aircraft includes a housing having a gimbal coupled thereto that is operable to tilt about first and second axes. A propulsion system is coupled to and operable to tilt with the gimbal.

Stall recovery chine spoiler system

A chine spoiler system enhances aircraft wing stall recovery characteristics while optimizing a maximum lift coefficient (clmax) of an aft-swept wing on an aircraft having an engine nacelle mounted below the wing. The system includes a chine located on a surface of the nacelle; the chine is configured to generate a vortex at high angles of attack.

Stopping device, moving mechanism and aircraft

The present application relates to a stopping device, a moving mechanism and an aircraft. The moving mechanism is connected to a stationary structure of the aircraft so as to allow the moving mechanism to move relative to the stationary structure.

Hydrogen recycling flight system and flight method

The present invention relates to a hydrogen recycling flight system and flight method, the hydrogen recycling flight system including: a flight fuselage which has at least one pair of wings at each of both sides of a body; a hydrogen gas balloon which is air-tightly connected to the flight fuselage; a hydrogen fuel cell which is connected with the hydrogen gas balloon and is installed outside or inside the flight fuselage; and a secondary battery which is charged with electricity generated from the hydrogen fuel cell, electricity generated from a solar cell provided at an outer peripheral portion of the flight fuselage, or electricity of an external power network, in which by using a switch, the hydrogen fuel cell is switched to a water electrolysis device or the water electrolysis device is switched to the hydrogen fuel cell, the hydrogen recycling flight system includes: a water tank which stores water generated from the hydrogen fuel cell; the water electrolysis device which electrolyzes the stored water; a switch control device which switches functions of the hydrogen fuel cell and the water electrolysis device; and a high-pressure gas barrel which high-pressure stores hydrogen gas and oxygen gas generated in the water electrolysis device, and the flight fuselage flies by controlling the volume of the hydrogen gas balloon that is flotation power of a flight vehicle by an operation of the hydrogen fuel cell or the high-pressure gas barrel.. .

Motion control device and motion control ship

To provide a motion control device for a ship, which does not require adjustment of weights of an performance function, and is less liable to fail in control calculation by building optimization calculation only into a part of classical feedback control, the motion control device, which is configured to cause a ship, on which a plurality of outboard engines are installed, to cruise along a desired trajectory, includes: a trajectory generator configured to output a trajectory command; a controller configured to output a control force command based on the trajectory command and a sensor information group output from a sensor group provided for the ship; and a control force distributor configured to carry out, based on the control force command, optimization calculation for operation amounts required for the plurality of outboard engines in accordance with a constraint condition set in advance so as to output the operation amounts.. .

Underwater watercraft

An underwater watercraft including a passenger compartment and an ingress/egress port in which the watercraft has buoyancy and center of gravity adjusted to maintain a generally level or other desired attitude when submerged, and an optionally angled attitude at a water surface for ingress/egress. The attitude is also adjustable via the placement of ballast and optionally including a movable ballast that adjusts the location of the center of gravity as desired.

Tow body arrangement for a towable device in a sonar system

A tow body arrangement for a towable device in a sonar system includes a bridle having a front for connecting to a first tow cable and back for connecting to a second tow cable. The tow body arrangement also includes a tow body rotatably connected to the bridle between the front and back of the bridle.

System, method, and determining a communication status of locomotives in a distributed power system

Provided is a computer-implemented method for determining a communication status in a train consist operating in a distributed power system, the train consist including a lead locomotive and a plurality of remote locomotives. The method includes, for each remote locomotive of the plurality of remote locomotives that receives the command message directly from the lead locomotive, setting the message source indicator of the remote locomotive to a first state representative of a direct receipt of the command message, incrementing the message source counter for each response message received by the remote locomotive from other remote locomotives in which the respective message source indicator is set to the first state, generating a response message including a value of the message source indicator and a value of the message source counter, and transmitting the response message.

Encoder bearing hub assembly for rail vehicles

The present disclosure generally relates to a bearing hub assembly of a rail guide wheel apparatus for a rail vehicle. The bearing hub assembly may couple rail wheels to the rail guide wheel apparatus.

Control vehicle

A control apparatus for a vehicle that includes an engine includes an electric generator, a lock up clutch, a throttle valve, an electric generator control unit, a clutch control unit, and a throttle control unit. The clutch control unit is configured to control the lock up clutch to an engaged state on the condition that the electric generator performs the regenerative power-generation.

Control apparatus of electric vehicle

A control apparatus of an electric vehicle including a motor capable of outputting a vehicle driving force that is a driving force acting on the electric vehicle, and a brake device configured to generate a vehicle braking force that is a braking force acting on the electric vehicle in accordance with a brake operation performed by a driver, includes: a controller. The controller is configured to start a first hill-hold control for maintaining the electric vehicle in a stopped state by using the vehicle driving force generated by the motor as a stopping force for stopping the electric vehicle when the brake operation is interrupted..

Vehicle driving control apparatus and method thereof

The present disclosure provides a vehicle driving control apparatus and a method. The apparatus includes an engine configured to generate a power; a clutch positioned between the engine and a transmission and configured to selectively connect the engine and the transmission; a state detector configured to detect state data to control a driving of a vehicle; and a controller configured to determine a stopping line based on a difference between the vehicle and a stopping line when an entry condition is satisfied based on the state data, determine whether a driving control condition is satisfied based on a lighting color of a traffic signal light positioned at the stopping line and the stopping line distance, confirm a deceleration rate depending on a clutch engagement when the driving control condition is satisfied, and control a clutch to decelerate a vehicle speed based on a stop prediction position depending on the deceleration rate..

Speed control system for controlling the speed of a vehicle

A speed control system for controlling a speed of a vehicle to a predetermined target speed is provided, wherein in order to achieve and maintain the target speed, a control unit transmits corresponding control signals to a drive unit or a brake unit, and wherein the control unit is configured, during active speed control, to detect the end of a manually triggered temporary acceleration request, to detect the actual speed at the end of a manually triggered temporary acceleration request and to generate a signal to initiate a coasting mode if, after the ending of the manually triggered temporary acceleration request, the actual speed is greater than the predetermined target speed.. .

Autonomous vehicle constant speed control system

A hybrid electric vehicle includes an engine, an electric machine, and a battery, coupled to a controller(s) configured to, in response to a virtual-driver signal, predict and maintain a constant-speed from a plurality of candidate speeds, to have a lowest fuel consumption and a minimum number of battery-charge-cycles, for a predicted distance and wheel-torque-power. A predicted engine-power is established from the wheel-torque-power required to maintain the constant-speed, and to power vehicle accessories and battery charging, such that fuel consumption and battery-charge-cycles are minimized over the predicted distance at the constant-speed.

Aircraft brake and tire condition diagnosis and prognosis

A method of diagnosis and prognosis for various operative systems is provided so that maintenance can be efficiently and effectively scheduled and provided. The invention is applicable to a broad range of systems, but particularly to aircraft brake systems and tires.

Brake control device

Provided is a brake control device in which a stable intermediate opening degree can be achieved. The amount of energization for energizing a solenoid of an electromagnetic valve is calculated in accordance with upstream-downstream pressure difference of the electromagnetic valve before the end of hydraulic pressure adjustment of a braking force generator.

Brake lock detection system for towed vehicles

Brake lock detection is described for a brake activation system. In one example, a main housing is configured to engage an interior surface of a towed vehicle near a brake pedal of the towed vehicle.

Airbag device for a motor vehicle, and airbag cushion for an airbag device

An airbag device for a motor vehicle, the airbag device can be provided on and secured to a seat frame and is designed to protect the head and rib cage of an occupant in the event of side impact or vehicle rollover. The airbag device has a gas generator, an airbag cushion and a first securing system, the first securing system, the gas generator and the airbag cushion being connected to one another to secure the airbag device to the seat frame.

Multi-chamber airbags and associated methods of manufacture and use

Multi-chamber airbag systems for use in aircraft and other vehicles are described herein. In some embodiments, an occupant restraint system includes a multi-chamber airbag that deploys from an occupant restraint (e.g., a lap seat belt) in an aircraft.

Vehicle control system

Provided is a vehicle control system that appropriately performs synchronization control for a plurality of control systems. A monitoring circuit generates a command signal when only a first reset signal is input.

Lamp assembly for a vehicle

A lamp assembly for a vehicle is disclosed. The assembly includes a reflector having a proximal end and a distal end.

Lighting device for vehicles

A lighting device for vehicles having a housing in which is arranged a hologram light fixture that has a light source unit and has an optical unit with a hologram element for generating a predetermined lighting function. An auxiliary element is associated with the light source unit, by means of which light that is emitted by the light source unit can be deflected in the direction of the hologram element.

Controlling active isolation platform in a moving vehicle

Systems and methods for actively isolating a payload from a disturbance. In one example, a seat system for a vehicle includes a seat, a support structure that allows the seat to move about an axis of a pivot, a first sensor positioned to detect movement of the vehicle, a second sensor positioned to detect lateral acceleration of the pivot, an actuator configured to move the seat, and a controller configured to receive a first signal from the first sensor and a second signal from the second sensor, generate a command signal based at least on the first and the second signal to instruct the actuator to position the seat at a desired command angle, wherein the controller is configured to correct the command signal for lateral accelerations caused by steering the vehicle, and provide a force command to the actuator to move the seat at the desired command angle..

Vehicle power supply control method and vehicle power supply control device

A vehicle power supply control device includes a main battery connected to a power supply circuit, a sub-battery having an internal resistance lower than an internal resistance of the main battery, an electric generator which is connected to the power supply circuit and has a controllable power generation voltage, and a connection controller configured to connect the sub-battery to the power supply circuit after adjusting a voltage on a side of the power supply circuit close to a voltage of the sub-battery by controlling the power generation voltage of the electric generator. The main battery is configured to be disconnectable from the power supply circuit.

Drone docking system

A drone docking system is disclosed that is connected to a drone. The drone docking system has a positioning member that connects to the drone and is configured to rotate the angle of the drone from a generally horizontal position to a generally vertical position.

Vehicle architectures, devices and control algorithms for managing wireless vehicle charging

Disclosed are control algorithms and system architectures for managing wireless vehicle charging, including vehicles with rechargeable battery packs, wireless charging capabilities, and control logic for governing such charging. A method is disclosed for managing charging of an electrical storage unit of a motor vehicle at a wireless vehicle charging station.

Vehicle thermal management system with vortex tube

A thermal management system for a vehicle includes a vortex tube configured to generate hot and cold airstreams and a valve having hot and cold air inlets connected to the vortex tube to receive the hot and cold airstreams, respectively. The valve further has a vent and a valve outlet.

On-board unit and electric vehicle management system

A charge management method includes generating and storing a charge schedule related to an electric energy for charging a vehicle within an amount of suppliable electric power for charging said vehicle located in a region, wherein said vehicle includes a rechargeable battery. The method further includes storing an identification number of said vehicle in said region by an ev controlling center.

Adjustable airflow assembly and a vehicle

An adjustable airflow assembly and a vehicle include a body. The assembly includes a brake apparatus and a flap attached to a second panel portion proximal to an opening.

Amphibious marsh craft

A tracked, amphibious vehicle, comprising at least two, spaced, elongated pontoons disposed generally parallel to one another. A platfofin structure can be supported by and structurally connects the pontoons, the platform structure including a transom, a lowermost generally horizontally extending panel above a free clearance area under a bottom panel and between the pontoons through which terrain and debris can pass.

Construction vehicle tire

To provide a construction vehicle tire capable of reducing compression strain generated in a carcass folded portion and improving durability of a bead portion even in a state closer to an actual use environment in which large lateral force is input. In a construction vehicle tire (1) according to the present invention, when mounted to a wheel rim (100), a height (ha) of a carcass cord (31) of a carcass body (40) corresponding to the minimum value a from a base line (bl) of the wheel rim (100), a height (hb) of the carcass cord (31) of the carcass body portion (40) corresponding to the maximum value b from the base line (bl), and a flange height (hf) of the wheel rim (100) from the base line (bl) fulfill relations of 1.2 hf≤ha≤2.5 hf, 2.6 hf≤hb≤3.5 hf, and 1.10≤b/a<1.40..

Progressive buffer generation

Example implementations relate to progressive buffer generation. Some examples may include a drive system to advance print media through a print zone at a printing speed and a buffer speed calculation system to calculate a buffer generation speed based on the printing speed, a length of a plot to be printed, a minimum buffer, a buffer start position and an amount of time required to cut the print media.

Sensing media and a media tray

In an example implementation, a device for sensing media and a media tray includes a sensor to transmit light toward a media tray port, and to generate current from light received at the sensor. The device also includes a circuit to convert the current into a voltage signal to be compared with a threshold for determining one of a media present condition, a media empty condition, and a media tray absent condition..

Data generation method, computer-readable storage medium, and structure manufacturing method

M to the first surface bs and is closer to the expansion layer m2 than the first surface bs. The first material forming the first pattern p1 is irradiated with electromagnetic waves from the first surface bs.

Fluid recirculation channels

A fluid recirculation channel for dispensing a plurality of fluid drop weights includes a number of sub-channels. The sub-channels include at least one pump channel, and a plurality of drop generator channels fluidically coupled to the at least one pump channel.

Process of manufacturing droplet jetting devices

A process of manufacturing droplet jetting devices includes bonding together a nozzle wafer defining nozzles of the jetting devices, a membrane wafer carrying, on a membrane, actuators for generating pressure waves in a liquid in pressure chambers that are connected to the nozzles, and a distribution wafer forming a distribution layer that defines supply lines for supplying the liquid to the pressure chambers from a liquid reservoir formed on a side of the distribution layer opposite to the membrane wafer; and dicing the bonded wafers. The distribution layer has a thickness larger than the thickness of each of the other two wafers.

Liquid discharge device and inkjet printer including the same

A driving signal generating circuit generates, for each driving period, a main driving signal including a first sub driving signal including a first driving pulse, a second sub driving signal including a second driving pulse, and a third sub driving signal including a third driving pulse. The third sub driving signal follows the second sub driving signal.

Generating three dimensional projections

One embodiment provides a method, including: receiving, at an information handling device, user input to generate a three dimensional projection of an object in physical space; generating, using a projection source, a plurality of perspective views of the object, wherein each of the plurality of perspective views is associated with a different angle of the object; and providing, using the plurality of perspective views, the three dimensional projection of the object at a predetermined location in the physical space using at least one reflective surface. Other aspects are described and claimed..

Additively manufactured component having localized density variations for part identification

A method for additively manufacturing a component is provided. The method includes additively manufacturing an identifying region of the component including localized density variations that define a component identifier of the component.

Color three-dimensional printing method and three-dimensional printing equipment

A color three-dimensional printing method and three-dimensional printing equipment are provided, which are adapted to present a color pattern on a three-dimensional object. The method includes following steps.

Method for printing a model for 3d printer

A method for printing a model for a 3d printer includes: perform a slicing process on an outer-frame object for generating multiple slicing-route files of multiple printing layers; perform the slicing process on a modeling object for generating multiple inkjet graphic files of the multiple printing layers; print a slicing object of one printing layer according to corresponding one of the slicing-route files; perform a filling process to the inside of the printed slicing object; perform a coloring process on the inside of the printed slicing object according to one of the inkjet graphic files corresponding to the same printing layer; and re-execute the above printing steps until all the printing layers are printed. The inside of the 3d model is colored via the inkjet graphic files generated after processing on the modeling object generating the visual effect that the modeling object is accommodated within the 3d model..

Method and system of vacuum loading

The present invention relates to a method and system of vacuum loading powder used in rotational molding. A loader has a hopper with a tangential inlet at the top and a discharge assembly at the bottom.

Prepreg with variable cure rate resin composition

A prepreg comprising a layer of impregnated reinforcing fibers comprising at least one layer of reinforcing fibers impregnated by a resin composition comprising at least a thermosetting resin, a curing agent and an accelerator, such that the accelerator has a gradient concentration which is more concentrated in the resin composition in the vicinity of the reinforcing fibers than further away. The resin composition comprising a first resin composition impregnates the reinforcing fibers to provide a layer of impregnated reinforcing fibers and a surface layer comprising a second resin composition is formed on the layer of impregnated reinforcing fibers, wherein the first resin composition has at least one peak exotherm occurring at a time earlier than and/or at a temperature lower than any peak exotherm of the second resin composition.

Two wheeled robot with enhanced climbing features

A robot has an electronic surveillance system embedded within a chassis disposed between two wheels. The wheels include a main body and a plurality of treads.

Offline programming apparatus and method having workpiece position detection program generation function using contact sensor

An offline programming apparatus includes a first part which causes an operator to designate contact points at which a contact sensor arranged at a distal end of a robot contacts a workpiece on a 3d model of the workpiece, a second part which automatically adds detection starting points in operations of the robot which approaches each of the contact points in directions of movement along coordinate axes of a reference coordinate system with reference to which the operation of the robot to detect the position of the workpiece is performed, at positions where no interference occurs between the robot and the workpiece in a virtual space, and a third part which automatically adds an interference avoidance point in the virtual space in order to avoid the interference if the robot and workpiece interfere with each other on a movement path of the robot which moves between the detection starting points.. .

System and flexible human-machine collaboration

Methods and systems for enabling human-machine collaborations include a generalizable framework that supports dynamic adaptation and reuse of robotic capability representations and human-machine collaborative behaviors. Specifically, a method of feedback-enabled user-robot collaboration includes obtaining a robot capability that models a robot's functionality for performing task actions, specializing the robot capability with an information kernel that encapsulates task-related parameters associated with the task actions, and providing an instance of the specialized robot capability as a robot capability element that controls the robot's functionality based on the task-related parameters.

Device, system, and automatically generating motion path of robot

A device that can prevent a decrease in an efficiency of a manufacturing line. The device includes a shape acquisition section for acquiring a shape of a workpiece; a motion pattern acquisition section for acquiring basic motion patterns including a reference workpiece shape, a reference working position in the reference workpiece shape, and a type of an operation carried out on the reference working position; a similarity determination section for determining whether a shape of the workpiece is similar to the reference work piece shape; a position determination section for, based on a shape of the workpiece and the reference workpiece shape, determining the working position on the workpiece that corresponds to the reference working position; and an motion-path generation section for, by changing the reference working position to the determined working position, generating a motion path..

Teaching device, display device, teaching program, and display program

A teaching device teaches tasks to a polar robot including an extendable arm supported to be able to turn and vertically rotate, and generates and displays a process chart representing the outline of the tasks of the robot. In the process chart, a plurality of hand task graphic elements each expressed in a form corresponding to a kind of a hand task of the polar robot are disposed along a first axis in an order, each of the hand task graphic elements is disposed along a second axis orthogonal to the first axis in accordance with a height of a hand reference point, each of the hand task graphic elements is rotated in accordance with a turning angle of the arm, and the hand task graphic elements are linked by link lines between the hand task graphic elements, each link line expressing a change in expansion and contraction length of the arm or turning radius of the hand reference point in a form of at least one of changes in hue, chroma, brightness, and line width..

Manipulator system, controller and computer-readable storage medium

A manipulator system of the present invention includes a manipulator driven by a motor, an operating part for generating an operation input for operating the manipulator, and a controller for controlling the motor. The controller controls for receiving a first current and a first voltage of the motor, for calculating a first resistance value of the motor on the basis of the first current and the first voltage, for controlling the motor to rotate thereof under a predetermined angle, for receiving a second current and a second voltage of the motor after rotating the motor, for calculating a second resistance value of the motor based on the second current and the second voltage, for adopting the larger one of the first resistance value and the second resistance value as a calculated resistance value, and for controlling the motor based on the operation input and the calculated resistance value..

Device for discharging chips

Provided is a device discharging chips, which is configured to allow smooth transfer because it is possible to absorb transformation of connecting pins due to a force generated while chain belts are operating as well as smoothly discharging a coolant and chips.. .

Additive manufacturing apparatus and methods

An additive manufacturing apparatus including a build chamber, build platform lowerable in the chamber so layers of flowable material can successively form across the platform, laser for generating a laser beam, scanning unit for directing the laser beam onto each layer to selectively solidify the material and a processor for controlling the scanning unit. The processor controls the scanning unit directs the laser beam to solidify a selected area of material by advancing the laser beam many times along a scan path.

Methods and systems for coherent imaging and feedback control for modification of materials

Methods and systems are provided for using optical interferometry in the context of material modification processes such as surgical laser or welding applications. An imaging optical source that produces imaging light.

Methods and apparatuses for dispensing solder

Automation of soldering work may be difficult, in part because present systems may be configured to dispense solder in a uniform preset amount. Provided are systems and methods in which soldering products (such as soldering paste and soldering wire) are dispensed adjustably.

Clamping device and machining unit comprising such a clamping device

A clamping device for clamping a workpiece or a tool or, more specifically, a tool holding fixture in a machine part of a machine tool includes a tension rod slidably mounted within the machine part; a clamping set movable by the tension rod between clamped and released positions; a tension spring dedicated to the tension rod so as to generate the pull-in force of the clamping set; and a release mechanism, by which the clamping set can be moved against the force of the tension spring into the released position by the tension rod. To make possible effective clamping at optimum force, the tension spring is clamped between first and second rod parts of the tension rod.

Production apparatus and production fine particles

A production apparatus for fine particles includes a vacuum chamber, a material supply device, a plurality of electrodes arranged and a collection device connecting to the other end of the vacuum chamber and collecting fine particles, which generates plasma and produces fine particles from the material particles, in which a first electrode arrangement region on the material supply port's side and a second electrode arrangement region apart from the first electrode arrangement region to the collection device's side which respectively cross a direction in which the material flows between the vicinity of the material supply port and the collection device are provided in the intermediate part of the vacuum chamber, and both the first electrode arrangement region and the second electrode arrangement region are provided with a plurality of electrodes respectively to form the electrodes in multi-stages.. .

System and continuous casting

A continuous casting apparatus includes a first belt carried by a first upstream pulley and a first downstream pulley, a second belt carried by a second upstream pulley and a second downstream pulley, and a mold region defined by a first mold support section arranged behind the first belt and a second mold support section arranged behind the second belt. The first mold support section supports the first belt and defines a shape of the first belt in the mold region and the second mold support section supports the second belt and defines a shape of the second belt in the mold region.

Deep geologic disposal of nuclear waste

Systems and methods for long term disposal of high level nuclear waste in deep geologic formations are described. Such systems and method may include largely intact spent nuclear fuel rods in a disassembled form that may be placed into waste-capsules (e.g., carrier tubes); which may then be placed into various well boreholes.

System and monitoring a fluidized slug in a piping conduit

A system and method for monitoring a fluidized slug in a piping conduit. The system includes a first sensor assembly positioned at a first location of the piping conduit, a second sensor assembly positioned at a second location of the piping conduit, the second location being downstream from the first location, and a monitoring controller.

Ultrasonic probe

An ultrasonic probe includes: an acoustic element that generates an ultrasonic wave and detects the ultrasonic wave; a support that supports the acoustic element on a side opposite to a test object side; and a heat dissipation material disposed on a side of the support opposite to the acoustic element, wherein an attenuation/thermal conduction material made of an attenuating material containing a thermally conductive material is disposed in contact with the heat dissipation material.. .

Depositing of material by spraying precursor using supercritical fluid

Embodiments relate to surface treating a substrate, spraying precursor onto the substrate using supercritical carrier fluid, and post-treating the substrate sprayed with the precursor to form a layer with nanometer thickness of material on the substrate. A spraying assembly for spraying the precursor includes one or more spraying modules and one or more radical injectors at one or more sides of the spraying module.

Microfluidic delivery device for dispensing and redirecting a fluid composition in the air

A microfluidic delivery device is provided. The microfluidic delivery device includes a housing electrically connectable with a power source.

Microfluidic delivery device and dispensing a fluid composition upward into the air

A microfluidic delivery device and method of dispensing a fluid composition therefrom is provided. The microfluidic delivery device includes a housing electrically connectable with a power source; a cartridge releasably connectable with the housing; and a fan connected with the housing.

Tangential air cleaner with coiled filter cartridge

Filtration systems having a tangential air cleaner having a coiled media filter element and a cyclonic pre-cleaner are described. An outer wall of the filter element acts as a pre-cleaner sleeve of the housing to generate a cyclonic flow of the intake air prior to the intake air being filtered by the filter element.

Photocatalyst electrode and artificial photosynthesis module

A photocatalyst electrode decomposes water with light to generate gas. The photocatalyst electrode has a laminate including a substrate, a conductive layer provided on a surface of the substrate, and a photocatalyst layer provided on a surface of the conductive layer, and a first co-catalyst electrically connected to the photocatalyst layer.

Reusable adsorbents for removal and purification of hydrophobic materials from fluids

Embodiments of the present disclosure pertain to adsorbents for removing hydrophobic materials from a fluid. The adsorbents include a modified clay and a binding material associated with the modified clay.

Dehumidifier

Provided is a dehumidifier capable of preventing condensation from flowing to the outside of a water container when the dehumidifier is turned over or while the dehumidifier is moved, since a suction structure for suctioning the condensation and a discharge structure for discharging the condensation are improved. The dehumidifier comprises: a main body having a suction port; a heat exchanger provided inside the main body and removing moisture in the air; and a water collection device for collecting the condensation generated in the heat exchanger, wherein the water collection device comprises: an auxiliary water container in which the condensation is collected; a housing for guiding the condensation to the auxiliary water container; a connection hose provided to have a bent part so as to connect the auxiliary water container and the housing; an upper water container detachably provided at the upper part of the main body so as to drain the condensation; and a pump for pumping, to the upper water container, the condensation collected in the auxiliary water container..

Mid-range purity oxygen by adsorption

The present invention relates to a process cycle that allows for the stable production of mid-range purity oxygen from air, using traditional system designs. Typical cycles have a limited production benefit when generating o2 at lower than 90% purity, however they suffer a production loss at higher purity.

Process for generating higher vpsa product pressure

The invention relates to a process for modifying the vpsa/vsa/psa cycle to allow for maximum product pressure without the need for a base load oxygen compressor (bloc) or base load oxygen blower (blob), thus supplying low pressure oxygen (3 to 7 psig) to the end user while at the same time lowering product costs 10 to 30%. The system of this invention preferably employs larger piping runs from the vpsa to the oxy-fuel control skids, larger piping for the oxy-fuel control skid, larger piping for the vpsa, low pressure drop flow measurements, and low pressure drop check valves..

Modular, high-throughput air treatment system

Air treatment modules, systems and methods for removing contaminants from indoor air are provided. Device embodiments may include one or more air inlets, one or more air outlets and a plurality of inserts which each include at least one adsorbent material.

Gas-solids separation system having a partitioned solids transfer conduit

A solids discharge system (sds) is configured to separate solids from product gas. The system includes a solids separation device and at least one solids transfer conduit configured to receive solids from the solids separation device.

Multi-use acoustic levitation trap

Disclosed is a device, suitable for use as an acoustic resonator, including a base adapted to be coupled to at least one acoustic wave generator, a spacer including an aperture and a reflector, wherein the base includes a protruding part having a thickness t; the aperture of the spacer is complementary to the protruding part of the base; the device further includes a housing having an aperture complementary to the protruding part of the base and wherein the inner edge of the aperture has the same thickness t than the protruding part; and the housing is positioned between the spacer and the reflector, such that the thickness of the inner edge of the spacer defined the thickness of a cavity between the protruding part and the reflector. Also disclosed is a method of trapping particles in a fluid..

Sulfur seal device

Embodiments of the invention are directed to a sulfur trap comprising an inlet, a first chamber, a divider, a second chamber, an outlet, and a float assembly. The float assembly may have many different configurations, but generally comprises a float and plug, is configured to float within liquid sulfur, and is operatively coupled to a seal seat in the divider for sealing and unsealing the first chamber from the second chamber.

Vacuum waste removal system

A scum removal system for use with a wastewater treatment clarification tank containing wastewater is provided and includes a debris intake conduit, a debris discharge conduit, and a pump article. The pump article is configured to be in flow communication with the debris intake conduit and the debris discharge conduit, wherein the pump article and debris intake conduit are configured to generate a suction within the debris intake conduit and wherein the debris intake conduit is configured to be located proximate the wastewater.

Method and system for designing and producing a user-defined toy construction element

A computer-implemented method of generating a digital representation of a user-defined construction element connectable to pre-manufactured toy construction elements of a toy construction system, each pre-manufactured toy construction element comprising a number of coupling elements for coupling the pre-manufactured toy construction element with one or more other pre-manufactured toy construction elements of said toy construction system, the method comprising determining one or more positions for placement of one or more coupling elements to be included in the user-defined construction element; generating, responsive to input by a user indicative of a user-defined shape, a digital representation of a user-defined construction element, the user-defined construction element comprising said one or more coupling elements at said determined one or more positions; providing the digital representation for automated production of said user-defined construction element.. .

Systems and methods for executing a training program based on player dna

A method for executing a training program based on player dna is described. The method includes executing a video game and determining whether a skill level of a user is below a threshold level of play.

Stream testing for cloud gaming

A method is provided, including: receiving, over a network by a cloud gaming server computer, a request from a client device to initiate gameplay of a cloud video game; assigning the client device to a data center from which to stream the cloud video game; loading a cloud gaming machine at the data center with the cloud video game; substantially simultaneous with the loading of the cloud gaming machine, performing a stream test between the data center and the client device to determine a quality of service of the streaming of the cloud video game; after completion of the loading and the stream test, initiating interactive gameplay of the cloud video game by streaming video data, generated from execution of the cloud video game by the cloud gaming machine, to the client device, and receiving input data from the client device to drive the execution of the cloud video game.. .

Playing card dispenser and display apparatus

A card dispenser and display apparatus for securely loading, maintaining, removing and displaying game cards during the playing of a game. The apparatus includes a housing and a generally planar base.

Electrically powered ride-on vehicle with intuitive control

In an aspect, a powered vehicle is provided, and includes a body to support a rider. At least one wheel is rotatably coupled to the body to enable travel of the body over a travel surface.

Golf system

A golf system includes a striking area; a target area including a plurality of physical targets positioned at different locations relative to the striking area; and at least one sensing device for sensing parameters regarding the travel of a physical golf ball. A processor is configured to: access a database including golf hole data, the golf hole data defining relative positions of a tee-off location and a pin location for a virtual golf hole; based on the one or more parameters regarding the travel of the physical golf ball struck from the striking area, update a virtual location of a virtual golf ball on the virtual golf hole; and generate signals to provide an indication of which of the plurality of physical targets represents a direction of the pin location based on the virtual location of the virtual golf ball and the locations of the physical targets..

Grappling dummy

A grappling dummy having a generally human shape includes a trunk with a head, arms, and legs extending from the trunk. The legs can be connected together by a connecting leg segment forming a leg enclosure.

Instrumented batting system

An instrumented batting system measures a bat speed and an exit velocity as a batter swings a bat and initiates contact between the bat and a ball positioned on a batting tee assembly. The batting tee assembly includes a bat speed radar device and an exit velocity radar device each in communication with a computing device.

Golf club head

A golf club head comprises a body having a face, a crown and a sole together defining an interior cavity. The body having a channel located on the sole and extending generally from a heel end of the body to a toe end of the body.

Golf club heads and methods to manufacture golf club heads

Examples of golf club heads and methods to manufacture golf club heads are generally described herein. In one example, a body portion of a golf club head may include a front portion.

Device for training coordinative faculties

The invention relates to a device for training coordinative faculties. The device has at least one movable standing plate; at least one static base plate; at least two connecting elements, the height of which can be modified and which act between the at least one movable standing plate and the at least one static base plate, a user interface; and a control element.

Explicit prediction of adversary movements with canonical correlation analysis

Described is a system for prediction of adversary movements. In an aspect, the system includes one or more processors and a memory, the memory being a non-transitory computer-readable medium having executable instructions encoded thereon, such that upon execution of the instructions, the one or more processors perform operations of computing relative positions of multiple objects of interest, generating a feature representation by forming a matrix based on the relative positions, predicting movement of the multiple objects of interest by applying clustering to the feature representation and by performing canonical correlation analysis, and controlling a device based on the predicted movement of the multiple objects of interest..

Leg stretching apparatus

A stretching machine of two seat having bases and backrests which is pivotally mounted to the base including a first leg platform having a pivot end and a free end, the pivot end being connected to the base of the seat and a second leg platform having a pivot end and a free end, the pivot end being connected to the base of the seat. The stretching machine includes a mechanism for rotating the backrest relative to the seat as well as a mechanism for rotating the leg platforms about their respective pivot ends such that the free ends move in a generally arcuate path..

Wall mounted exercise rack system

A retractable wall mounted exercise rack system for providing an exercise rack that may be easily and compactly stored when not in use. The retractable wall mounted exercise rack system generally includes one or more brackets attached to a wall, a pair of support members, and a plurality of arms pivotally extending from the brackets and pivotally connecting to the support members.

Low cost, multi-function exercise platform

An exercise platform having a base member being a firm, resilient structure having in some aspects an edge member or a surrounding frame. The shape of the base member varies on design considerations, one shape being a generally planar, pear shape, another rectangular with side extensions.

Electric exercise assistance device

The present invention relates to an exercise assistance device for assisting muscle exercise by means of a motor driven by means of electronic control. An electric exercise assistance device, according to the present invention, comprises: sensors comprising a first sensor and a second sensor; a motor driven by means of a control signal and generating an external force; a micom for correcting the frictional driving force inside an exercise assistance device and deriving a calculation value of exercise assistance point, exercise assistance intensity and exercise assistance location on the basis of an encoder signal, the exercise speed and the number of exercise sets detected by means of the first sensor, exercise intensity, and user information; a mount detachably attached to a vertical frame of a rack used for muscle exercise; a base rail for guiding the movement of a safety bar; a power transmission unit for transmitting the power of the motor to the safety bar; the safety bar for enabling application of an external force, which is required for exercise assistance and exercise, and enabling detachment and attachment of a barbell rod for muscle exercise; and a rest for resting a weight material, used for muscle exercise, at an exercise starting location..

Safety dose interlock for charged particle beams

An assembly for preventing an overdose of a charged particle beam during therapy to a patient includes a pixelated detector apparatus and a controller. The controller includes, for each pixel: a current integrator circuit that converts the local measured current into a total local detected charge integrated from a start time, the integrator circuit outputting an integrator voltage that corresponds to the total local detected charge; and a discriminator circuit that compares the integrator voltage with a reference voltage, the reference voltage corresponding to a maximum acceptable dose for the patient.

Sequential monoscopic tracking

A method of sequential monoscopic tracking is described. The method includes generating a plurality of projections of an internal target region within a body of a patient, the plurality of projections comprising projection data about a position of an internal target region of the patient.

Particle beam therapy apparatus

A particle beam therapy apparatus includes: a particle beam irradiator outputting a particle beam; a movable supporting structure supporting the particle beam irradiator; movable plates disposed on a displacement trajectory of the particle beam irradiator, forming a substantially horizontal enveloping surface below a table for placing an irradiation object, and including first and second floor members in at least one of the movable plates, the second floor member being larger in x-ray transmittance than the first floor member; an x-ray generator provided in a non-collision area where the x-ray generator does not collide with any of the particle beam irradiator, the supporting structure, and the movable plates; and an x-ray detector installed at a position where the x-ray detector faces the x-ray generator.. .

Treatment apparatus using proton and ultrasound and treating cancer using the same

Provided are a treatment apparatus using proton and ultrasound and a method for treating cancer using the same. The treatment apparatus includes a proton generator configured to emit a proton beam to a tumor of a human body, an ultrasound generator configured to emit an ultrasonic beam to the tumor in a direction crossing an emission path of the proton beam, and a sensor configured to measure an acoustic signal generated during the emission of the proton beam..

Midfield transmitter and receiver systems

Generally discussed herein are systems, devices, and methods for providing a therapy (e.g., stimulation) and/or data signal using an implantable device. Systems, devices and methods for interacting with (e.g., communicating with, receiving power from) an external device are also provided..

Variation of spatial patterns in time for coordinated reset stimulation

This document discusses a medical device for coupling to a plurality of implantable electrodes. The medical device includes a therapy circuit, a biomarker sensing circuit, and a control circuit operatively coupled to the therapy circuit and biomarker sensing circuit.

Complex variation of electrical stimulation therapy parameters

Techniques for delivering electrical stimulation therapy comprising a complex variation to at least one electrical stimulation parameter are described. In one example, processing circuitry of an implantable medical device (imd) identifies a plurality of electrical stimulation parameters for at least one pulse train of electrical stimulation.

Spinal cord stimulator system

Spinal cord stimulation (scs) system having a recharging system with self alignment, a system for mapping current fields using a completely wireless system, multiple independent electrode stimulation outsource, and control through software on smartphone/mobile device and tablet hardware during trial and permanent implants. Scs system can include multiple electrodes, multiple, independently programmable, stimulation channels within an implantable pulse generator (ipg) providing concurrent, but unique stimulation fields.

Spinal cord stimulator system

Spinal cord stimulation (scs) system having a recharging system with self-alignment, a system for mapping current fields using a completely wireless system, multiple independent electrode stimulation outsource, and ipg control through software on smartphone/mobile device and tablet hardware during trial and permanent implants. Scs system can include multiple electrodes, multiple, independently programmable, stimulation channels within an implantable pulse generator (ipg) providing concurrent, but unique stimulation fields.

Implantable pulse generator that generates spinal cord stimulation signals for a human body

An implantable pulse generator (ipg) that generates spinal cord stimulation signals for a human body has a programmable signal generator that can generate the signals based on stored signal parameters without any intervention from a processor that controls the overall operation of the ipg. While the signal generator is generating the signals the processor can be in a standby mode to substantially save battery power..

Intratumoral modulation therapy

An intratumoral modulation therapy (imt) method for the treatment of nervous system and systemic tumor in a patient which includes: (a) chronically implanting an electrode adjacent to or in the tumor of the patient or in a residual tumor bed, the electrode having electrical leads connected thereto; and (b) generating electric stimulation and applying the electric stimulation through the electrical leads to the electrode adjacent to or within the tumor. A method of transferring genetic material to a tumor cell which includes: (a) positioning an electrode adjacent to the tumor cell, the electrode having electrical leads connected thereto; (b) generating electric stimulation and applying the electric stimulation through the electrical leads to the electrode adjacent the cancer cell; and (c) delivering the genetic material to the tumor cell treated with the continuous alternating electric stimulation..

Detection of lead electrode dislodgement using cavitary electrogram

Methods and systems for identifying dislodgement of an electrode, operably coupled to an implanted medical device, from fixation with the endocardium of a chamber of the heart of a patient can include obtaining a test electrogram, and measuring at least two parameters indicating a cavitary electrogram and taking an action, such as generating an electrode dislodgement alert and/or configuring the implanted medical device to disable therapy, when the cavitary electrogram is indicated. In embodiments, the two parameters include a test positive component magnitude and a test negative component magnitude.

Medical connector

A soft grip medical connector comprises a housing with an upstream end, a downstream end and a lumen extending through a central portion thereof. A flexible member comprises a valve portion integrally formed with a sleeve portion.

Ultraviolet sleeves for percutaneous devices and methods for using and/or providing the same

An exemplary ultraviolet (uv) arrangement, can be provided, which can include, for example, a lumen structured to be inserted into a body of a patient and pass a percutaneous structure therethrough into the body of the patient, wherein the lumen can be configured to disperse or provide a uv radiation, and an optical arrangement coupled to the lumen, and configured to generate the uv radiation, and provide the uv radiation to the lumen to be dispersed or provided by the lumen. The lumen can include a weave of a plurality of strands.

Balloon catheter system

A balloon resection method is disclosed generally including inserting a catheter with at least one balloon having an outer wall with a resecting, non-slip surface for resecting unwanted biological material, such as tissues or tumors, and supplying fluid thereto in pulsed fashion to repeatedly deflate and inflate the balloon. In certain embodiments, a pump controls the pulsed supply of fluid based on an established frequency or change in volume.

Brainwave regulation device and brainwave regulation method

A brainwave regulation device adapted to transmit signals to or receive signals from a control device. The brainwave regulation device includes a head-wearable element, a control module, at least one brainwave sensor and at least one ear bone oscillator.

Mechanical ventilation with automatic control of patient's work of breathing using classical feedback control

A mechanical ventilator (10) provides pressure support ventilation (psv) to a patient (12). A power of breathing (pob) or work of breathing (wob) estimator (30) generates a pob or wob signal (34) for the patient.

Connectors for connecting components of a breathing apparatus

A breathing apparatus includes components, including, but not limited to, a flow generator, a patient interface, and a delivery conduit. A connector for connecting components of the breathing apparatus includes a male connector, including a recess, extending from a first component, and a female connector, including a lever pivotally connected thereto, extending from a second component.

Aromatherapy vaporization device

A vaporization device includes a housing, a fluid pathway extending through the housing, a heating chamber with a heating element proximate a first housing end, a control circuit and a battery disposed within the housing. The heating chamber is in fluid communication with the fluid pathway.

Aerosol-generating system comprising a rupturing portion

An aerosol-generating system is provided, including an aerosol-generating device including a heater element, and an aerosol-generating article configured to engage with the aerosol-generating device, the aerosol-generating article including a medicament source, a volatile delivery enhancing compound source, and at least one frangible barrier sealing the medicament source and the volatile delivery enhancing compound source, the aerosol-generating system further including a rupturing portion forming part of the aerosol-generating device or the aerosol-generating article, the aerosol-generating system being configured to allow relative sliding movement between the rupturing portion and the at least one frangible barrier to rupture the at least one frangible barrier.. .

Methods and systems for measuring and heating dialysate

The present specification provides a dialysate management system for generating, weighing, and heating a dialysate fluid during a dialysis treatment. The dialysate management system includes a container and base enclosure.

Methods and systems for an external drive unit for an implantable heart assist pump

The application relates to an external drive unit (7) for an implantable heart assist pump. The proposed drive unit (7) comprises a motor (35) for driving the heart assist pump, wherein the motor (35) is connectable to the heart assist pump via a transcutaneous drive shaft (3).

Vacuum assisted dressings, systems and pumps for surgical incisions and seroma management

A vacuum overdressing sealing a wound. The dressing has a layer of overdressing that is generally rectangular with a top side and a bottom side and two longer ends and two shorter ends.

Fluid management apparatus and method

In one example embodiment, a vibration apparatus can augment and enhance negative-pressure therapy systems. The apparatus can be attached to an external surface of a dressing, fluid conductor, or other components.

Ready to use biodegradable and biocompatible artificial skin substitute and a preparation thereof

The present invention relates to a three-dimensional cell culture system which can be used to culture a variety of different cells (human mesenchymal stem cells, human fibroblast, keratinocytes, fibroblast differentiated form mesenchymal stem cells in vitro and keratinocytes differentiated form mesenchymal stem cells in vitro) in vitro for continued periods of time. In the present invention, mesenchymal stem cells (mscs) derived from bone marrow or umbilical cord are inoculated and grown on a pre-established scaffold or matrix made up of chitosan and gelatin.

Medical base material

Provided is a medical base material that is suitable for regeneration of a cardiovascular system being exposed to high pressure from a lumen, such as an aorta and is absorbed by a living body after transplantation. The medical base material of the present invention has a sheet shape, a tube shape, or a combined shape thereof and is used for regeneration of a cardiovascular system by being transplanted in a body.

Tissue scaffold materials for tissue regeneration and methods of making

Disclosed herein are tissue scaffold materials with microspheres of one density embedded in hydrogel of a different density. The disclosed materials have improved ability to facilitate cellular invasion and vascularization for wound healing and tissue regeneration.

Composite materials for bone repair based on decellularized biological tissue matrix material and the preparation method thereof

A composite material for bone repair based on a decellularized biological tissue matrix material and a preparation method thereof. The composite material for bone repair comprises an organic phase of a microfibrillar decellularized animal tissue matrix material and an inorganic phase of a calcium salt bioceramic or other inorganic bioglass.

Membrane for guided bone regeneration and a method thereof

A membrane having at least one strip of a shape memory material and the at least one strip is sandwiched between a first layer and a second layer. A method for guiding bone regeneration which excludes the use of a tenting screw is also disclosed.

Preclinical model of neonatal necrotizing enterocolitis

The disclosure provides methods of generating a murine model of neonatal necrotizing enterocolitis, whereby the generated murine animal exhibits at least one symptom of neonatal necrotizing enterocolitis. The disclosure also provides methods to measure transfusion effects on anemia and methods for identifying and isolating an agent useful for the treatment or prevention of neonatal necrotizing enterocolitis..

Method for evaluating hematological toxicity of drug under evaluation, and model for evaluating hematological toxicity of drug under evaluation

The method for evaluating the hematotoxicity of the drug to be evaluated, the method including: administering the drug to be evaluated to humanized, transgenic nog mouse, which is obtained by introducing human gm-csf/il-3 gene into nog mouse and the number of human-derived leucocytes in leucocytes in blood thereof is 20% or more; and evaluating that the drug to be evaluated has the hematotoxicity when sample of the humanized, transgenic nog mouse after the administering the drug to be evaluated is measured for number of cells of human-derived hemocytes, the number of the cells of the human-derived hemocytes is changed compared to control to which vehicle is administered instead of the drug to be evaluated.. .

Intranasal therapeutic delivery of adeno-associated virus to central nervous system

A method to prevent, inhibit or treat one or more symptoms associated with disease of the central nervous system by intranasally, intrathecally, intracerebrovascularly or intravenously administering a raav encoding a gene product associated with the disease, e.g., a mammal in which the gene product is absent or present at a reduced level relative to a mammal without the disease, in an amount effective, e.g., to provide for cross-correction.. .

Immunogenic compositions and reagents for preparing

The invention described herein pertains to compounds and conjugates, to compositions, complexes and formulations comprising the compounds and/or conjugates, and to methods of use of the compounds, conjugates and their compositions, complexes and formulations in vaccines and vaccinations and generating immune responses.. .

Controlled drug release from electrospun fibers

Embodiments of the invention relate generally to electrospun fibers and, more particularly, to the controlled release of an active pharmaceutical ingredient (api) from electrospun fiber scaffolds (efss).. .

Early cancer detection and enhanced immunotherapy

A method of therapy for a tumor or other pathology by administering a combination of thermotherapy and immunotherapy optionally combined with gene delivery. The combination therapy beneficially treats the tumor and prevents tumor recurrence, either locally or at a different site, by boosting the patient's immune response both at the time of original therapy and/or for later therapy.

Molecular adjuvant and vaccine

The invention relates to the fields of vaccines and vaccine adjuvants, and generally relates to polynucleotide adjuvants, polynucleotide vaccines and vaccine compositions. More specifically, the invention relates to said polynucleotides and vaccine compositions for use in inducing or enhancing a prophylactic or therapeutic immune response in a mammalian subject.

Stable live attenuated recombinant dengue vaccine

The present invention relates to field of live attenuated recombinant tetravalent dengue vaccines and methods of producing stable compositions. Present invention specifically relates to a stable composition and methods of using such a stable composition comprising live attenuated recombinant dengue virus, stabilizer, bulking agent and optionally buffering agents, wherein the live attenuated dengue virus is generated from Δ 30 and or Δ 31 deleted or mutated dengue strains.

Bacterial vaccine components and uses thereof

Agents, compositions, methods and kits useful for the treatment and diagnosis of staphylococcal intramammary infection are disclosed. The agents, compositions, methods and kits are derived from genes expressed during staphylococcal intramammary infection, and more particularly genes sacol0029, sacol0264, sacol0442, sacol0718, sacol0720, sacol1353, sacol1416, sacol1611, sacol1944, sacol2144, sacol2365 or sacol2599, based on the gene nomenclature from the staphylococcus aureus col (sacol) genome..

Pharmaceutical composition for preventing or treating hair loss comprising chemokine (c-x-c motif) ligand 1 (cxcl1) protein or cxcl1 protein and minoxidil as active ingredient

Provided is a composition for preventing, treating or improving hair loss and promoting hair generation and hair growth, comprising a cxcl1 protein as an active ingredient. Further, provided is a composition for preventing, treating or improving hair loss and promoting hair generation and hair growth, comprising a cxcl1 protein and minoxidil as an active ingredient.

Compositions and methods for invasive and non-invasive procedural skincare

Compositions and methods for skincare treatment are provided. The invention relates more generally to skin care treatment and more particularly, to compositions and methods for promoting healthy skin, skin regeneration, skin repair, skin bed preparation, and enhanced wound healing..

Mutant adeno-associated virus virions and methods of use thereof

The present invention provides mutant adeno-associated virus (aav) that exhibit altered capsid properties, e.g., reduced binding to neutralizing antibodies in serum and/or altered heparin binding and/or altered infectivity of particular cell types. The present invention further provides libraries of mutant aav comprising one or more mutations in a capsid gene.

Conditioned medium from human adult liver stem cells and its use in the treatment of liver disorders

The invention relates to cell-free compositions obtained by culturing adult-derived human liver stem/progenitor cells (adhlsc) in cell culture medium and isolating the resulting conditioned medium (adhlsc-cm) that has advantageous properties, such as anti-fibrotic effects. Adhlsc-cm, compositions based on adhlsc-cm, and other related and derived products, can be used in cell culture processes or as a medicament, more particularly for the treatment of diseases involving organ injury, organ failure, in organ or cell transplantation or the pathological disruption, inflammation, degeneration, and/or proliferation of cells within a tissue or an organ, in particular within liver..

Human cd8+ regulatory t cells inhibit gvhd and preserve general immunity

Graft-versus-host disease (gvhd) is a lethal complication of allograft transplantation. The current strategy of using immunosuppressive agents to control gvhd may cause general immune suppression and limit the effectiveness of allograft transplantation.

Method for preparing genetically-modified t cells which express chimeric antigen receptor

In order to improve the efficiency of gene introduction in car therapy employing a transposon method, provided is a method for preparing genetically-modified t cells expressing chimeric antigen receptor, comprising: (1) a step of preparing non-proliferative cells which are obtained by stimulating a group of cells comprising t cells using an anti-cd3 antibody and an anti-cd28 antibody followed by a treatment for causing the cells to lose their proliferation capability; (2) a step of obtaining genetically-modified t cells into which a target antigen-specific chimeric antigen receptor gene has been introduced using a transposon method; (3) a step of mixing the non-proliferative cells prepared by step (1) with the genetically-modified t cells obtained by step (2), and co-culturing the mixed cells while stimulating the mixed cells using an anti-cd3 antibody and anti-cd28 antibody; and (4) a step of collecting the cells after culture.. .

Engineered meganucleases with recognition sequences found in the human t cell receptor alpha constant region gene

Disclosed herein are recombinant meganucleases engineered to recognize and cleave a recognition sequence present in the human t cell receptor alpha constant region gene. The present disclosure further relates to the use of such recombinant meganucleases in methods for producing genetically-modified eukaryotic cells..

Combination therapy for treating proliferative diseases

The present invention relates generally to new chemical combinations and methods for their use in the treatment of proliferative diseases and in particular cancer.. .

Combination therapy for treatment of human neurodegenerative diseases

The present disclosure provides a combination therapy to treat neurodegenerative diseases. In one embodiment, alzheimer's disease is treated with an orally administered mitochondria stimulant, neuro protective antioxidant that crosses the blood brain barrier and is supplemented with a drug that promotes hippocampal neurogenesis.

Composition for preventing or treating vascular leak syndrome

The present invention relates to a pharmaceutical composition containing ginsenoside f1 or rh1 for preventing or treating vascular leak syndrome, to a method for treating vascular leak syndrome using the pharmaceutical composition, and to a food composition containing ginsenoside f1 or rh1 for preventing or ameliorating vascular leak syndrome. The ginsenoside f1 or rh1 provided in the present invention can promote angiogenesis and suppress vascular leakage, and thus can be widely utilized in the effective prevention or treatment of vascular leak syndrome..

Treatment of adipocytes

The present disclosure provides compositions comprising a lyn kinase activator and trpm8 agonist, and to methods of: reducing blood glucose levels, weight gain, or fat depot levels; treating metabolic syndrome, syndrome x, obesity, prediabetes, type ii diabetes, type i diabetes; treating hypercholesterolemia, hypertension, coronary heart disease, diabetic neuropathy, lipodystrophy, diabetic retinopathy, erectile dysfunction, kidney disease, dyslipidemia, dyslipoproteinemia, a peroxisome proliferator activated receptor-associated disorder, septicemia, a thrombotic disorder, or pancreatitis; inducing the beiging of adipocytes; and preventing pancreatic beta cell degeneration.. .

Combinations of inhibitors of irak4 with inhibitors of btk

The present application relates to novel combinations of at least two components, component a and component b: ⋅component a is an irak4-inhibiting compound of the formula (i) as defined herein, or a diastereomer, an enantiomer, a metabolite, a salt, a solvate or a solvate of a salt thereof; ⋅component b is a btk-inhibiting compound, or a pharmaceutically acceptable salt thereof; and, optionally, ⋅one or more components c which are pharmaceutical products; in which one or two of the above-defined compounds a and b are optionally present in pharmaceutical formulations ready for simultaneous, separate or sequential administration, for treatment and/or prophylaxis of diseases, and to the use thereof for production of medicaments for treatment and/or prophylaxis of diseases, especially for treatment and/or prophylaxis of endometriosis, lymphoma, macular degeneration, copd, neoplastic disorders and psoriasis.. .

Covalent small molecule dcn1 inhibitors and therapeutic methods using the same

Small molecule covalent inhibitors of dcn1 and compositions containing the same are disclosed. Methods of using the dcn1 covalent inhibitors in the treatment of diseases and conditions wherein inhibition of dcn1 provides a benefit, like oxidative stress-related diseases and conditions, neurodegenerative diseases and conditions, metabolic disorders, and muscular nerve degeneration, also are disclosed..

Compositions and methods to treat urinary tract infections

This invention relates to treating and preventing urinary tract infections. Glycerol monolaurate (gml) and/or gml-related compositions together with suitable accelerants in gel-based formulation may be used to treat urinary tract infections that may be generally diagnosed, for example, in women, catheterized patients and elderly individuals.

Graphene nanostructure-based pharmaceutical composition for preventing or treating neurodegenerative diseases

The present disclosure relates to a pharmaceutical composition for preventing or treating neurodegenerative diseases, the pharmaceutical composition including a graphene nanostructure as an active ingredient.. .

Skin cleanser

A skin cleanser includes a surface, such as a silicone surface, with at least one textured portion for transmitting vibrational tapping to the skin. The skin cleanser includes at least one oscillating motor for generating the tapping motion to the skin.

Reduced-pressure, wound-closure and treatment systems and methods

A reduced-pressure, wound closure system is presented that generates a closing force on a surface wound and optionally provides reduced pressure to a body cavity or tissue site. The sealed contracting member, when placed under reduced pressure, generates the closing force.

Extensible dressings

The present invention generally relates to dressings such as bandages or tapes having improved extensibility and conformability to human skin and joints.. .

Extensible dressings

The present invention generally relates to dressings such as bandages or tapes having improved extensibility and conformability to human skin and joints.. .

Point of delivery cold slurry generation

The present invention provides methods and devices for making a cold slurry at a point of delivery. A point of delivery device delivers cold slurry components to a location at or near a target tissue.

Device and safe access and automated therapy

An automated therapy system having an infusion catheter; a sensor adapted to sense a patient parameter; and a controller communicating with the sensor and programmed to control flow output from the infusion catheter into a patient based on the patient parameter without removing fluid from the patient. The invention also includes a method of controlling infusion of a fluid to a patient.

Portable traction device with sling

A sling of a portable traction device cradles a user's head and includes a pair of shock cords attached at opposite ends of the sling. The ends of the shock cords opposite shock cords are anchored is anchored to a structure, such as a closed door at the hinged side of the door, between the door and door frame, using an anchor, at a height, to generate a tension vector at an acute angle relative to the floor.

Surgical tools and kits for cartilage repair using placental, amniotic, or similar membranes

Surgical tools and kits are disclosed for repairing hyaline or meniscal cartilage, using membrane segments to protect and promote the growth and activity of cartilage-generating cells. These kits include: (i) a set of dilator tubes, adapted from similar tubes used in spinal surgery except shorter, that will allow a surgeon to progressively enlarge an insertion tunnel for inserting a membrane segment into an articulating joint that is being repaired; and, (ii) an assortment of membrane “tamping” devices, with smooth rounded “tamping heads” (or tips, etc.), and with a size and length that allow the tool tip to pass through the longest dilator tube while being held by the surgeon.

Intervertebral spacer and plate

Embodiments herein are generally directed to spinal implants, systems, apparatuses, and components thereof that can be used in spinal fusion and/or stabilization procedures, as well as methods of installation. The spinal implants may include an intervertebral spacer and a plate member..

Ringless web for repair of heart valves

A ringless web is configured to repair heart valve function in patients suffering from degenerative mitral valve regurgitation (dmr) or functional mitral valve regurgitation (fmr). In accordance with various embodiments, a ringless web can be anchored at one or more locations below the valve plane in the ventricle, such as at a papillary muscle, and one or more locations above the valve plane, such as in the valve annulus.

Prosthetic valve with axially-sliding frames

Embodiments of the present disclosure are directed to prosthetic valves and methods of use thereof. In one implementation, a prosthetic valve for implantation within a native mitral valve may be provided.

One-piece heart valve stents adapted for post-implant expansion

A prosthetic heart valve configured to replace a native heart valve and having a support frame configured to be reshaped into an expanded form in order to receive and/or support an expandable prosthetic heart valve therein is disclosed, together with methods of using same. The prosthetic heart valve may be configured to have a generally rigid and/or expansion-resistant configuration when initially implanted to replace a native valve (or other prosthetic heart valve), but to assume a generally expanded form when subjected to an outward force such as that provided by a dilation balloon or other mechanical expander..

Biliary stents and methods

A tissue lumen stent is provided with a body having an elongated tubular configuration and a foreshortened configuration. In the foreshortened configuration, downstream and upstream ends of the body expand radially into downstream and upstream flange structures, leaving a generally cylindrical saddle region therebetween.

Method and system for generating a model of a subperiosteal dental implant device and customized implant head

A method for generating a virtual model of a subperiosteal dental implant device. The method comprises: obtaining a virtual mouth model of a patient providing a three-dimensional representation of at least a section of a jaw bone of a patient, using a non-invasive modelling method; positioning at least one replacement tooth in relation to the section of the jaw bone defined by the virtual mouth model; positioning at least one implant head at a respective implant position; and designing and generating a virtual model of the subperiosteal dental implant device having a shape at least partially derived from a shape of the section of the jaw bone defined by the virtual mouth model and at least a portion of each one of the at least one implant head extending from the subperiosteal dental implant device at the respective implant position..

Medical manipulator system and operating method thereof

A medical manipulator system including: a placement table on which a patient is placed; at least one manipulator configured to support a treatment tool which is configured to treat the patient, the manipulator configured to adjust a position and an orientation of the treatment tool; a base portion configured to support the manipulator; a sensor configured to detect objects which are present in a predetermined area including the manipulator and the placement table; and a controller including at least one processor, wherein the processor is configured to: calculate degrees of proximity between the objects detected by the sensor and the manipulator, and generate, in case that the calculated degrees of proximity exceed a predetermined threshold, a control signal for preventing interference between the objects and the manipulator.. .

Medical manipulator system, control device of medical manipulator system, and control medical manipulator system

A medical manipulator system includes a slave manipulator, a master manipulator receiving a manipulation information from an operator; a driver generating a driving force for operating the slave manipulator; a processor; and a master-manipulator-side detector disposed at the master manipulator and detecting the manipulation information. The processor generates an operating command based on the manipulation information and transmits the operating command to the driver, the processor determines whether a blur information is included in the manipulation information.

System and coordinating a surgical procedure

Embodiments described herein provide a surgical management and coordination system and method of implementation. The system includes a microprocessor and integrated memory which provide recommended surgical coordination templates generated in successive phases corresponding to the various phases of a surgical procedure based on a specific bone set, surgeon or medical center.

Electromagnetic navigation device for guiding and tracking an interventional tool

An electromagnetic navigation device for guiding and tracking an interventional tool (40) within an anatomical region. The electromagnetic navigation device employs a guidewire (20) insertable into the anatomical region, and a hub (30) translatable and/or rotatable in conjunction with the interventional tool (40) relative to the guidewire (20).

Microwave ablation catheter and utilizing the same

A method for treating tissue through a branched luminal network of a patient is provided. A pathway to a point of interest in branched luminal network of a patient is generated.

Electroporation system and preconditioning tissue for electroporation therapy

The present disclosure provides electroporation systems and methods of preconditioning tissue for electroporation therapy. An electroporation generator includes an electroporation circuit, a preconditioning circuit, and a controller.

Surgical instruments with position-dependent actuator cooperation and impedance

Surgical instruments with position-dependent actuator cooperation and impedance are described herein. In general, movement of one actuator can cause proportional movement of another actuator depending upon the positions of each actuator.

System for controlling tissue ablation using temperature sensors

Body tissue ablation is carried out by inserting a probe into a body of a living subject, urging the probe into contact with a tissue in the body, generating energy at a power output level, and transmitting the generated energy into the tissue via the probe. While transmitting the generated energy the ablation is further carried out by determining a measured temperature of the tissue and a measured power level of the transmitted energy, and controlling the power output level responsively to a function of the measured temperature and the measured power level.

Steerable endoluminal punch with cutting stylet

A transseptal needle or punch is described wherein the distal end of the transseptal needle is able to articulate laterally out of the longitudinal axis of the steerable transseptal needle. The transseptal needle includes a blunted distal end configuration that is minimally traumatic.

Smart sensors with local signal processing

A device including smart sensors with a local signal processor is disclosed. The device includes an end-effector including at least one sensor and a signal processing component corresponding to the at least one sensor; and a handle configured to receive processed information from the signal processing component.

Staples for generating and applying compression within a body

Apparatus for generating, applying and maintaining compression to a site in a human or animal body, the apparatus comprising: a staple comprising: a bridge configured to be elastically bendable; a first leg connected to the bridge by a first hinge region configured to be elastically bendable; and a second leg connected to the bridge by a second hinge region configured to be elastically bendable; wherein the first hinge region comprises a first hole configured to mate with a first element of a delivery device and the second hinge region comprises a second hole configured to mate with a second element of a delivery device; and wherein the first and second legs are angled toward one another when they are in an unstrained state; whereby, when the staple is mounted to a delivery device so that the first hole of the first hinge region mates with a first element of a delivery device and the second hole of the second hinge region mates with a second element of a delivery device, and when the delivery device applies a force to the bridge of the staple so as to reconfigure the bridge of the staple, the first and second legs are pivoted away from one another toward a parallel disposition.. .

Ultrasound observation device, processing device, operating ultrasound observation device, and computer readable recording medium

A processing device includes a controller including hardware. The controller is configured to execute: generating an ultrasound image based on an ultrasound signal acquired by an ultrasound probe, the ultrasound probe being configured to transmit an ultrasonic wave to a subject that is an observation target and receive an ultrasonic wave reflected by the subject; generating shift information including a shift direction of a display area of the ultrasound image displayed on a display unit in accordance with a command position with respect to the ultrasound image; shifting the ultrasound image in accordance with the shift information; and generating a character image indicating an area targeted for a process performed on the ultrasound image in relation to the command position in the ultrasound image after being shifted..

Ultrasound observation device, operation ultrasound observation device, and computer-readable recording medium

An ultrasound observation device includes a controller. The controller is configured to: generate data on an ultrasound image based on an ultrasound signal; automatically set a second region of interest that is relatively stiff in a first region of interest preset within the ultrasound image; and generate data on first and second elastic images each having a display mode according to stiffness of the corresponding first and second regions of interest..

Dark-field enhanced virtual x-ray colonoscopy

A method of a virtual x-ray colonoscopy includes scanning (204) a dark-field contrast (144) insufflated colon lumen (140) with an x-ray scanner (110) configured for dark-field-contrast, which generates dark-field-contrasted projection data and attenuation projection data. The dark-field-contrasted projection data and the attenuation projection data are reconstructed (206) into one or more dark-field-contrasted images (148)..

Data-driven surrogate respiratory signal generation for medical imaging

Projection data are acquired by one or more gamma detectors of a medical imaging system. The counts for each projection are binned into time bins to provide respective frames.

Lock-block shield device

Apparatus and techniques for blocking radiation in a medical environment are described. In one or more embodiments, a lock-block shield device includes a base that is configured to adhesively couple to an object associated with a patient.

Medical image display device, method, and program

A classification unit classifies a lung region, which is included in each of two three-dimensional images having different imaging times for the same subject, into a plurality of types of case regions. A mapping image generation unit generates a plurality of mapping images corresponding to the three-dimensional images by labeling each of the classified case regions.

Method and system for monitoring intoxication

A method and system for monitoring a user's intoxication including receiving a set of signals, derived from a set of samples collected from the user at a set of time points; providing a sobriety task to the user proximal to a time point of the set of time points; generating a performance dataset characterizing performance of the sobriety task by the user; receiving a supplementary dataset characterizing a demographic profile of the user and/or a physiological state of the user; determining a set of values of an intoxication metric, derived from the set of signals; generating a predicted temporal profile of the intoxication metric for the user based upon the set of values, the set of time points, and the supplementary dataset; generating an analysis of the user's sobriety based upon the performance dataset and the predicted temporal profile; and providing a notification to the user based upon the analysis.. .

Device to detect and treat apneas and hypopnea

A method and apparatus for the treatment of sleep apnea events and hypopnea episodes wherein one embodiment comprises a wearable, belt like apparatus containing a microphone and a plethysmograph. The microphone and plethysmograph generate signals that are representative of physiological aspects of respiration, and the signals are transferred to an imbedded computer.

System and determining vessel size

A surgical system includes at least one light emitter generating light at a first intensity and an array of light sensors including a least one row of light sensors, individual light sensors in the row of light sensors adapted to generate a signal including a non-pulsatile component. The system also includes a controller coupled to the array of light sensors, the controller including an analyzer to determine the magnitudes of the non-pulsatile components at the individual light sensors in the row of light sensors, to determine if the non-pulsatile component transitions from a higher magnitude to a lower magnitude and from a lower magnitude to a higher magnitude, and if so, to determine if the first intensity should be changed to a second intensity..

System and monitoring glucose level

A system for monitoring glucose blood level of a user is disclosed. The system comprising an illumination unit configured for providing coherent optical illumination on a selected inspection region on the user body, a collection unit configured for collecting light returning from the inspection region and generating a plurality of image data pieces associated with speckle patterns in the collected light, and a control unit comprising a processing utility and storage utility comprising pre-stored calibration data, the processing utility is configured for receiving input data on a plurality of image data pieces from the collection unit and for processing said input data for determining correlation functions between different image data pieces and using said correlation functions and said pre-stored calibration data for determining data on glucose blood level of the user..

Health diagnostic fingerprint scanner

Systems and methods allow for evaluating health conditions based on fingerprints and other skin patterns. A smartphone or other personal electronic device captures patient scans, such as fingerprint patterns transmitted from a wireless fingerprint scanner.

Methods and systems for providing a breathing rate calibrated to a resonance breathing frequency

A target respiration rate is determined for a user where, when the user breathes at the target rate, the user's vagal tone is improved, which provides a physiological benefit to the user, e.g., stress reduction without drug intervention. The user is directed to breathe at different rates while heart rate and breathing rate are measured.

Hybrid electromagnetic field signal detection system for human bioelectrical signal monitoring

The present disclosure includes an electromagnetic field detection and monitoring system. The system includes passive detection, active detection, and signal processing capabilities.

System for processing analog neurological monitoring signals including digital transmission

A system includes a monitoring electrode for neurological monitoring and operable to generate an analog electrical signal from brain activity of a patient; an analog-to-digital converter in electrical connection with the monitoring electrode; a transmitter in electrical connection with the analog-to-digital converter for transmitting a digital electrical signal corresponding to the analog signal; a receiver in electrical communication with the transmitter and operable to receive the transmission of the digital electrical signal; and a digital-to-analog converter in electrical connection with the receiver for converting the digital electrical signal received by the receiver back to an analog electrical signal for processing by an analog amplifier.. .

System and blood pressure measurement

A system for use in monitoring blood circulation data of a user is disclosed. The system comprising a monitoring unit comprising at least one light source unit configured for providing and directing coherent illumination onto at least one selected inspection region on the user's body, and a collection unit configured for collecting light returning for at least a portion of the inspection region and generating a plurality of image data pieces associated with secondary speckle patterns in the collected light returning from said regions; and a control unit configured and operable for receiving said plurality of image data pieces, determining correlation functions between speckle patterns in consecutive image data pieces, processing said correlation functions for determining data indicative of at least two heart rate data sequence indicative of heart rate of the user, and determining data indicative of circulation pressure of the user in accordance with said data indicative of heart rate of the user measured at said first and second monitoring regions..

High signal-to-noise ratio light spectroscopy of tissue

A diagnostic system includes a light source having semiconductor sources, optical amplifiers, and fibers configured to deliver a first optical beam to a nonlinear element configured to broaden a spectrum of the first optical beam to at least 10 nanometers through a nonlinear effect in the nonlinear element, wherein a broadened-spectrum output beam comprises a near-infrared wavelength between 600-1000 nanometers. An interface device, having a cap with fiber leads configured to couple to the light source and to a receiver having one or more detectors, delivers the output optical beam to a tissue sample.

Systems and methods for detection of cognitive and developmental conditions

Systems, devices, and methods are described for the assessment, screening, monitoring, or diagnosis of developmental or cognitive conditions, including autism spectrum disorders (asd) by analysis of eye tracking data generated from feedback received as a result of display of specific predetermined visual stimuli to a subject or patient. Subsequent to a calibration phase, a testing procedure is performed by presenting predetermined stimuli (e.g., videos) to a subject via a display device.

Image generating apparatus, image generating method, and computer-readable medium

Provided is an image generating apparatus including: an acquisition unit configured to acquire tomographic data on an object to be inspected, the tomographic data being obtained by performing optical coherence tomography imaging of the object to be inspected through use of measurement light; an eccentric amount acquisition unit configured to acquire an eccentric amount of an optical axis of the measurement light with respect to the object to be inspected; and a generation unit configured to generate a tomographic image through use of the acquired tomographic data. The generation unit includes: a calculation unit configured to calculate, through use of the eccentric amount, an incident angle variation of the measurement light entering the object to be inspected, and an optical path length variation of the measurement light; and a correction unit configured to correct the tomographic data through use of the incident angle variation and the optical path length variation..

Biological object observation system and non-transitory computer-readable medium

A biological object observation system includes an observation optical unit, a photodetector, a display unit, a detection unit, and a processor. The observation optical unit includes an optical system that guides a luminous flux from a biological object and a drive unit that drives the optical system.

Endoscope system

An endoscope system includes: a light source that generates red, green, and blue laser lights; a light-guiding section including a first end portion into which the laser lights enter, and a second end portion from which the laser lights are applied to the subject; a light detection that detects reflection light from the subject, and outputs a detection signal according to the reflection light; a memory that stores a plurality of color correction parameters, each of which is set for each subject; and an image processing section that generates an observation image based on the detection signal, and performs color correction on the observation image based on at least one of the plurality of color correction parameters, which is selected according to the subject.. .

Endoscope apparatus

An endoscope apparatus includes an imager configured to detect reflected and scattered light of illumination light radiated to an observation object and output an imaging signal, the illumination light including light in three wavelength ranges corresponding to first, second, and third depth regions, and an image processor including an intermediate emphasis image generator configured to generate an intermediate emphasis image, based on a first emphasis image signal generated based on emphasis narrowband light, a first non-emphasis image signal generated based on non-emphasis narrowband, and image signals corresponding to all wavelength ranges not including the first emphasis and non-emphasis image signals, and a display image generator configured to generate a display image based on the intermediate emphasis image.. .

Endoscope system, processor device, and operating endoscope system

An endoscope system 10 includes an image acquiring unit 54 that acquires a first image and a second image, the first image being obtained by using first illumination light, the second image being obtained by using second illumination light at a different timing from the first image; a halation-region detecting unit 74 that detects a halation region; a calculated-image generating unit 73 that performs calculation by using the first image and the second image and that generates a calculated image; a display-image generating unit 77 that generates a display image in which a tone reflects the calculated image; and a tone changing unit 75 that changes the tone of the halation region in the display image.. .

Automatic cleaning device and cleaning method

An automatic cleaning device includes: a sensor system for collecting a pre-set environment parameter of surroundings of the automatic cleaning device; and an application processor. The application processor includes a central processing unit electrically coupled to the sensor system to acquire the pre-set environment parameter collected by the sensor system.

Vacuum cleaner

A vacuum cleaner capable of detecting a shape of an object with high precision. A vacuum cleaner includes a main casing, driving wheels, a control unit, a plurality of cameras, an image generation part, and a shape acquisition part.

Temperature homogenization, protection, and grease guide structure of barbecue grill

Disclosed is a temperature homogenization, protection, and grease guide structure of a barbecue grill, including at least one burner, a grate, and a grease guide and temperature barrier board. The burner includes a heat generation section and is arranged in an inclined, upward-facing manner in a barbecue grill.

Method and cartridge-based carbonation of beverages

Systems, methods and cartridges for carbonating or otherwise dissolving gas in a precursor liquid, such as water, to form a beverage. A gas source can be provided in a cartridge which is used to generate gas that is dissolved into the precursor liquid.

Measuring device and dispensing system

The present disclosure relates generally to a measuring device comprising an upper body and a lower body. The upper body comprises a chamber having a top opening and a bottom opening, wherein a substance to be measured is placed in the top opening.

Reclosable cup lid with sliding member

Reclosable cup lids are provided herein. The reclosable cup lid can have a rim portion defining an outer perimeter.

Inflatable travel sleep aid

The invention is a sleep aid, and more particularly an inflatable sleep aid utilizing a series of c-shaped inflatable bladders joined in series to such that the height of the sleep aid is adjustable and forming a generally c-shaped channel to allow the user to comfortably breath.. .

Heating blanket for motorized wheelchair

A heating blanket for a motorized wheelchair comprising: a windproof and waterproof fabric which covers a thermal lining having velcro fasteners attached to at least one position thereof, has windproof and waterproof functions, and has a zipper and a zipped entrance/exit formed on the front and back sides thereof; at least one heating plate which is inserted into a back side windproof and waterproof fabric via the zipper and is detachably mounted on the thermal lining, wherein the heating plate is woven with carbon yarns so that the heating plate generates heat when electricity is applied; an electric wire, a connection part, an adjustment part, and a connection jack for supplying electricity to the heat plate, wherein the heating blanket is characterized in that the connection jack is connected to the outside to allow the heating plate to be heated.. .

Adjustable back support assembly for the back of a chair

An adjustable back support assembly coupled to the back of a chair in which a user sits with his back spaced from the chair back. The adjustable back support assembly includes a back support that is pivotally connected to the back of the chair by a hinge.

Oral care implement

An oral care implement in one embodiment includes an elongated body comprising a head portion supporting plurality of tooth cleaning elements and a handle portion. The tooth cleaning elements are disposed on longitudinally extending bristle carrier sections hingedly coupled together about a common pivot axis.

Back-carryable shooting kit and use thereof

A back-carryable shooting kit including a generally planar shooting table surface defining element adapted for attachment thereof to shoulder straps, shoulder straps removably attachable to the generally planar shooting table surface defining element and a tripod support assembly, removably and rotatably connectable to the generally planar shooting table surface defining element for support thereof.. .

Intelligent umbrella and intelligent shading charging system receiving messages from a mobile computing or communications device

An intelligent umbrella includes a wireless transceiver to receive commands or messages from a mobile computing device and an integrated computing device, the integrated computing device including one or more memory devices, one or more processors and computer-readable instructions stored in the one or more memory devices. The computer-readable instructions are executable by the one or more processors to receive the commands or messages, via the wireless transceiver from the mobile computing device and to generate instructions, signals, commands and/or messages, based, at least in part on the received commands or messages from the mobile computing device.

Sports shoes

The invention discloses a pair of sports shoes comprising a shoes body, a pressure generating device, a humidity sensor, a controller and a switch valve. A shoes chamber is provided at the heel of the shoes body, and the pressure generating device is arranged in the groove chamber.

Helmet with audio features

A helmet configured to provide audio features for the user thereof and a method for the same. The helmet comprises a first communication interface for communications with an audio source.

Atomizing assembly for use in an aerosol-generating system

An atomizing assembly includes a tubing section having an inlet end and an outlet end. The inlet end of the tubing section is connectable to a liquid storage portion, and the outlet end of the tubing section is in fluid communication with an atomizing nozzle.

Aerosol-generating devices

An aerosol-generating device comprises a device housing comprising a first receiving chamber configured to receive and accommodate a first consumable and a second receiving chamber configured to receive and accommodate a second consumable. The device further comprises a power source in an internal space defined by the device housing and a controller configured to control aerosolization of an aerosol-forming substrate in a consumable in one of the first receiving chamber and in the second receiving chamber.

Susceptor for use with an inductively heated aerosol-generating device or system

An inductively heatable susceptor for use with an inductively heated aerosol-generating device or system includes an open-porous inductively heatable ceramic material configured to hold an aerosol-forming liquid and configured to heat the aerosol-forming liquid under the influence of an alternating electromagnetic field. A cartridge for use with an aerosol-generating device includes an aerosol-forming liquid and a susceptor.

Electronic cigarette

An electronic cigarette includes a power supply device, a sensing unit, an atomizer, a liquid storage structure, a fluid transportation device, a casing and a mouthpiece. The atomizer includes an electric heater and a liquid receiving part.

Electronic cigarette

An electronic cigarette includes a power supply device, an atomizer, a liquid storage structure, a fluid transportation device and a sensing unit. The atomizer includes an electric heater.

Electronic cigarette

An electronic cigarette includes a power supply device, a sensing unit, an atomizer, a liquid storage structure and a fluid transportation device. The atomizer includes an electric heater and a liquid conduit.

Electronic cigarette

An electronic cigarette includes a power supply device, an atomizer, a liquid storage structure, a fluid transportation device, a casing and a mouthpiece. The atomizer includes an electric heater and a liquid conduit.

Electronic cigarette

An electronic cigarette includes a power supply device, a sensing unit, an atomizer, a liquid storage structure and a fluid transportation device. The atomizer includes an electric heater and a liquid receiving part.

Electronic cigarette

An electronic cigarette includes a power supply device, a sensing unit, an atomizer, a liquid storage structure and a fluid transportation device. The atomizer includes an electric heater, a liquid absorption part and a liquid guiding seat.

Machine for producing substantially cylindrical articles

Machine and method for producing a substantially cylindrical article, which comprises a tubular body, a container element, arranged in the area of one end of the tubular element, a heat generating element, partially housed inside the container element, and loose material for generating flavour; in use, the loose material is inserted into the container element, vertically oriented, and the heat generating element is partially inserted into the container element by being moved downwards, so as to obtain a combined element; subsequently, the combined element is at least partially inserted into the tubular body.. .

Smoking apparatus with a pump and a using same

A smoking apparatus has a vessel, a smoke-generation structure coupled to a lower portion of the vessel for accommodating smoke-generation substance for generating smoke, and for guiding the smoke into the vessel, a smoke guide for discharging the smoke out of the vessel, and a pump for pumping the smoke from the smoking generation structure into the vessel and for pumping the smoke out of the vessel through the smoke guide.. .

Methods and compositions for reducing contamination on food contact surfaces

Embodiments disclosed herein provide methods for decontaminating food contact surfaces using a fine spray/mist that comprise an antimicrobial composition comprising an organic acid and an organic citrus extract. The spray application reduces the microbiological populations on the surface of food contact surfaces, including potential pathogens, thereby reducing cross-contamination and improving food safety.

Methods of preserving the biological activity of ribonucleic acids

The present invention provides a method of substantially retaining or otherwise preserving the biological activity of a dsrna, present in a cell lysate, to post-transcriptionally silence the expression of a gene in a target organism, comprising the step of adding to the lysate a compound having the function of a protein- or amine-cross linking agent. The invention also comprises compositions comprising the lysate comprising dsrna, and protein cross linking agents, as well as the use of said agents in the method..

Novel compounds for controlling arthropods

The invention relates inter alia to compounds of the general formula (i). Also described are methods for preparing the compounds of the formula (i).

Transgenic silkworms expressing spider silk

Transgenic silkworms stably expressing synthetic spider silk genes or composite silkworm/spider silk genes are disclosed. The exogenous spider silk genes are stably intergrated into a defined site of the fibroin heavy chain intron or a fibroin light chain intron of silkworms.

Genetically modified major histocompatibility complex animals

The invention provides genetically modified non-human animals that express chimeric human/non-human mhc i polypeptide and/or human or humanized β2 microglobulin polypeptide, as well as embryos, cells, and tissues comprising the same. Also provided are constructs for making said genetically modified animals and methods of making the same.

Method of producing infertile fish and egg-producing aquatic animals and of delivering compounds into eggs and embryos

Methods for the production of reproductively sterile fish and aquatic animals for aquaculture, the aquarium trade, and control of invasive species are described. The methods include disruption of gonadal development through the administration of compounds that lead to the failure of fertile gonadal development.

Multiplexed genome editing

A method of modulating some or all copies of a gene in a cell is provided including introducing into a cell one or more ribonucleic acid (rna) sequences that comprise a portion that is complementary to all or a portion of each of the one or more target nucleic acid sequences, and a nucleic acid sequence that encodes a cas protein and maintaining the cells under conditions in which the cas protein is expressed and the cas protein binds and modulates the one or more target nucleic acid sequences in the cell.. .

Beehive status sensor and tracking pesticide use in agriculture production

Monitoring system, device and method for detecting chemicals in an insect environment, such as a beehive or colony. The method can include monitoring the insect environment for the presence of at least one chemical or environmental factor using at least one sensor located within the insect environment, the at least one sensor operative to generate data in response to the presence of at least one chemical or factor in the environment and communicate the data to an associated data processing device, monitoring a population of insects in the insect environment to detect a change in the population or health of insects that make up the population, and generating a correlation between a detected change in the population or health of insects in the insect environment with an increase or decrease of the at least one chemical outside the insect environment..

Stackable and pallet-transportable cheese log forming and holding tray

A tray that eliminates the need for wrapping or packaging edible food articles that are in a malleable form, such as when made or otherwise produced, with the tray formed with at least a plurality of pairs of article holding compartments each three dimensionally contoured so as to define an edible food article mold that shapes or forms an edible food article received therein that is in a formable or moldable state so as to substantially conform at least a portion of the edible food article to the shape of the three-dimensional contour of the mold of the compartment in which the article is received. A preferred embodiment of the tray has at least a plurality of pairs of elongate article holding compartments that are generally parallel with one another with the article shaping or forming mold defined by each compartment formed of a compartment sidewall that has a concavely curved cross-section that preferably is generally semicircular in a transverse cross-section.

Introgression of a yield qtl in cucumis sativus plants

The present invention relates to cultivated cucumber plants comprising a yield qtl on chromosome 3 of their genome, and to methods for generating such plants, and their use.. .

Yield traits for maize

Methods for introgressing an allele of interest of a locus associated with a yield trait into zea mays germplasm are provided. In some embodiments, the methods include providing a zea mays plant that contains an allele of interest of a locus associated with a yield trait, wherein the locus associated with the yield trait is identifiable by pcr amplification of a zea mays nucleic acid with a pair of oligonucleotides primers as disclosed herein, and introgressing the allele of interest into zea mays germplasm that lacks the allele.

Plant raising apparatus

A plant raising apparatus: a light source that emits light traveling toward an aboveground part of a plant; a heat insulating portion that has a light transmitting property and that partitions a space at a side of the light source and a space at a side of the aboveground part; and an air blowing mechanism that generates an airflow at a space between the light source and the heat insulating portion. Thereby, it is suppressed that the heat of high temperature air staying above the heat insulating portion having a light transmitting property adversely affects the plant..

Fertilizer tube system

A fertilizer tube system for efficiently dispensing and placing fertilizer within a furrow to minimize germination injury. The fertilizer tube system generally includes a fertilizer tube having an input opening at an upper end of the fertilizer tube and an output opening at a lower end of the fertilizer tube, an upper connector attached to an upper portion of the fertilizer tube, a central connector attached to a central portion of the fertilizer tube and a lower connector attached to a lower portion of the fertilizer tube..

Bacteria engineered to treat a disease or disorder

Genetically programmed microorganisms, such as bacteria, pharmaceutical compositions thereof, and methods of modulating and treating a disease and/or disorder are disclosed.. .

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Low noise rotor blade design

A rotor blade includes an elongated body having a leading edge, a trailing edge, a proximal end, and a distal end; a fluid inlet; a fluid outlet arranged near the distal end of the elongated body; and a fluid duct contained within the elongated body, the fluid duct being substantially open between the fluid inlet and the fluid outlet, the fluid duct having a shape to reduce fluid velocities c generated by the interaction of fluid exiting the fluid duct and external fluid at the distal end.. .

Active flow control system

An aircraft is provided and includes a fuselage including a top and a tail, a main rotor apparatus disposed at the top of the fuselage, which rotates one or more rotors to generate lift, and an active flow control (afc) system. The afc system includes plasma actuators configured to generate plasma at a location adjacent to the main rotor apparatus and/or at the tail of the fuselage..

Spanwise traveling electro pneumatic actuator systems and control logic for flow control applications

Disclosed are fluidic actuator systems for active flow control applications, methods for making/using such fluidic actuator systems, and vehicles equipped with fluidic actuators to modify airfoil aerodynamics. A spanwise traveling electro-pneumatic (step) actuator architecture for active flow control (afc) generates variable actuation using high-speed electronic valves to move an array of discrete jets in a spanwise direction.

Laser reflection aerodynamic control surface movement monitoring system

An actuator system for controlling a flight surface of an aircraft includes a first actuator having a first actuator input and a first linear translation element that moves based on rotational motion received at the first actuator input and a first laser distance sensor disposed inside the first actuator that generates a first output based on a displacement of the first linear translation element. The system also includes a second actuator having a second actuator input and a second linear translation element that moves based on rotational motion received at the second actuator input and a second laser distance sensor disposed inside the second actuator that generates a second output based on a displacement of the second linear translation element.

Aircraft with strut-braced wing system

An aircraft that comprises a body, a wing, and a strut. The wing is coupled to and extends from the body.

Solar powered boat

A solar powered aquatic vessel includes a hull having an overall length equal to a length of a waterline and a maximum hull draft at station that is located at a position that is approximately 30% of the overall length of the hull. A bottom of the hull has an approximately linear slope from a maximum beam to a transom forming a stern of the hull.

Aerodynamic system comprising a vortex generator supplied by exhaust gases

The invention relates to an aerodynamic system for a motor vehicle, which can be arranged close to at least one region of detachment of at least one bodywork element of a vehicle. The system includes at least one vortex generator which generates a vortex by creating a periodic air jet and is supplied by exhaust gases from an exhaust line outlet of the vehicle..

Front chassis structure for automobile

The present application discloses front chassis structure including set plate to which impact absorber is connected. Front chassis structure includes: pillar member having inner support plate portion for supporting impact absorber, outer support plate portion for supporting impact absorber in cooperation with inner support portion, and pillar portion having horizontal cross-section bulging rearward from inner and outer support plate portions; connection member for connecting pillar portion to vehicle body; front side member extending rearward from pillar member; and projecting member projecting outward from pillar member.

Method for the automated driving of a vehicle, in particular of a motor vehicle, in order to approach a parking position

A method for the automated driving of a transportation vehicle to approach a parking position which includes providing a trajectory for a controller of the transportation vehicle and generating signals for controlling a movement of the transportation vehicle along the trajectory provided, wherein the provision of the trajectory includes determining a current position of the transportation vehicle by a position-determining device, setting up a communication link to a server outside the transportation vehicle by a communication device, transmitting the current determined position of the transportation vehicle to the server via the communication link, retrieving and receiving at least one trajectory, stored at the server, via the communication link, wherein the retrieved and received trajectory runs at least through a tolerance range about the current determined position of the transportation vehicle. Also disclosed is a transportation vehicle device, a method for operating a system, and an associated system..

Automatic power saver for a locomotive battery

A power system for a locomotive includes a battery configured to provide electrical power to at least one component of the locomotive, an engine monitor for detecting whether an engine of the locomotive has been shut down, and an automatic power saver operatively associated with the battery. The automatic power saver includes a controller operatively associated with the engine monitor and configured to receive an input signal from the engine monitor, when the engine is shut down, and generate an output signal if the input signal is received.

Predictive teleassistance system for autonomous vehicles

A predictive teleassistance system cab monitor autonomous vehicles (avs) operating throughout a given region, and predict teleassistance locations within the given region. Using route data for a respective av, the system can determine a convergence of the respective av with the predicted teleassistance location, and generate a plurality of decision options for a human teleassistance operator to resolve the predicted teleassistance location for the respective av.

Method and system of assisting driving of vehicle

A vehicle drive assistance system is provided, which includes one or more processors configured to execute a general driver model learning engine configured to build a general driver model to be applied to a plurality of drivers based on driving data of the drivers, an individual driver model learning engine configured to build an individual driver model unique to a specific driver based on driving data of the driver, and an on-board controller provided in a vehicle operated by the driver. The individual driver model learning engine includes a vehicle control updating program configured to cause the on-board controller to update vehicle control processing based on the general and individual driver models.

Vehicle drive assistance system

A vehicle drive assistance system is provided, which includes one or more processors configured to execute a general driver model learning engine configured to build a general driver model to be applied to a plurality of vehicle drivers based on driving data of the plurality of vehicle drivers, an individual driver model learning engine configured to build an individual driver model unique to a specific driver based on driving data of the specific driver and the general driver model, and a vehicle control changing program configured to change vehicle control processing executed by a specific vehicle operated by the specific driver based at least on the individual driver model.. .

Vehicle drive assistance system

A vehicle drive assistance system is provided, which includes a general driver model learning engine configured to build a general driver model to be applied for a plurality of vehicle drivers based on driving data of the plurality of drivers, and an individual driver model learning engine configured to build an individual driver model particular to a specific vehicle driver based on the driving data of the specific driver received from a specific vehicle of the specific driver. The individual driver model learning engine includes a first synchronization engine configured to provide, to the general driver model learning engine, the driving data obtained by executing a first data conversion processing on the driving data of the specific driver..

Alert reduction in vehicles using map data

A method and system for identifying an object as a potential collision hazard for a vehicle. The system performs a method that includes sensing an object in a forward direction of travel of the vehicle with a sensor and determining a location of the vehicle.

Vehicle control device

Disclosed is a vehicle control device which is applied to a vehicle equipped with an engine (10) and an engine torque adjustment mechanism for adjusting an engine torque. The control device comprises a pcm (50) configured, upon satisfaction of a condition that the vehicle is traveling and a steering angle-related value relevant to a steering angle of a steering device is increasing, to control the engine torque adjustment mechanism to reduce the engine torque, so as to execute a vehicle attitude control for generating vehicle deceleration.

Hybrid powertrain speed control

A vehicle powertrain includes a controller, a torque converter, and an engine and electric machine coupled by a clutch. The torque converter may be configured to couple the electric machine to an output shaft.

Hybrid vehicle and controlling charge mode therefor

A hybrid vehicle and a method of controlling a charge mode therefor are provided. The control method includes determining a first torque, which is a currently requested torque and determining a second torque, which is a predicted requested torque that is predicted to be generated in the near future from the present time, or predicted acceleration.

Hev battery management for generating off-board power

A hybrid electric vehicle includes an internal-combustion engine (ice) and an electric machine coupled to a battery, an off-board power (obp) system, and a controller, which are configured to power internal vehicle and battery charge electrical loads, and external electrical loads. The controller monitors the electrical loads, and responds to an obp signal identifying an external electrical load, and commands the ice and electric machine to generate a combined-power greater than or equal to the loads.

Managing vehicle brake system

A method for managing a vehicle brake system includes collecting sensor data from one or more sensors in or around the vehicle, calculating brake effectiveness values based on the sensor data, calibrating the brake effectiveness values based on environmental context data associated with the vehicle, accumulating the calibrated brake effectiveness values as a dataset, generating a prediction curve or formula based the dataset, and scheduling a maintenance alarm for the brake system based on the brake effectiveness values.. .

Managing vehicle brake system

Managing a brake system of a vehicle includes collecting sensor data from one or more sensors in or around the vehicle, calculating brake effectiveness values based on the sensor data, calibrating the brake effectiveness values based on environmental context data associated with the vehicle, accumulating the calibrated brake effectiveness values as a dataset, generating a prediction curve or formula based the dataset, and scheduling a maintenance alarm for the brake system based on the brake effectiveness values.. .

Hydraulic assembly for a vehicle brake system

A hydraulic assembly for a vehicle brake system comprising at least two brake circuits and wheel brakes associated with the brake circuits. The hydraulic assembly comprises a pressure generator for generating a central hydraulic pressure for the brake circuits independently of the driver at least in the case of service braking initiated by the driver.

Brake device for vehicle

A brake device for a vehicle includes: braking devices provided corresponding to right/left wheels, respectively, the braking devices being configured to generate braking forces by pressing forces according to a depression amount of a pedal; a wheel speed sensor configured to detect rotational speeds of the wheels; a pressing force sensor configured to detect the pressing forces; and a control device configured to control the braking force generating devices. The control device is configured to acquire the rotational speeds and the pressing forces in a state where the braking device is performing braking, specify deceleration, based on the acquired rotational speeds, and specify the loads that are supported by the wheels, based on the specified deceleration and the acquired pressing forces and controls the pressing forces corresponding to the right/left wheels such that a difference in deceleration between the right and left wheels becomes smaller, based on the loads..

Pre-tensioner for seat belt of vehicles

A pre-tensioner for a safety belt of vehicles is provided. The pre-tensioner for a safety belt of a vehicle that is disposed in a side sill of the vehicle and that operates to pull the safety belt by pushing a piston into a tube by a high pressure gas of a gas generator using explosive power of gunpowder that is configured at one side of a bracket in a state in which the piston is connected to the safety belt through a wire within the tube including: internal and external weldnuts that are fixed to each one side of internal and external side surfaces of the side sill, wherein by penetrating the side sill in a vehicle width direction by forming a screw at an external circumference of both end portions of the tube, the both end portions are engaged with the internal and external weldnuts, respectively..

Airbag device for pedestrian protection

An airbag device for pedestrian protection adapted to be mounted on a vicinity of the rear end of a vehicle hood. The airbag includes a transverse inflatable portion that covers a cowl of the vehicle generally entirely in the vehicle width direction when deployed, and an inlet port that is disposed in a front end region of the transverse inflatable portion to be coupled with an inflator.

Airbag device

An airbag device includes an airbag, an inflator and a retainer. The retainer includes a generally tubular holding section for holding the inflator therein and mounting means which protrudes out of the holding section in a direction generally perpendicular to an axis of the inflator to be mounted on a vehicle body member in order to mount the airbag and the inflator on the vehicle body member.

Bird's-eye view video generation device, bird's-eye view video generation system, bird's-eye view video generation method and program

A bird's-eye view video generation device includes a video acquisition unit configured to acquire surroundings videos obtained by capturing videos of surroundings of a vehicle; a vehicle information acquisition unit configured to acquire vehicle information to estimate move of the vehicle in a turning direction; and a controller configured to, when move of the vehicle in the turning direction is estimated based on the vehicle information that is acquired by the vehicle information acquisition unit, generate a bird's-eye view video obtained by changing a position to display the bird's-eye view video containing a virtual vehicle image such that a surroundings video in a direction that has to be checked in the estimated turning direction is displayed widely. The generated bird's-eye view video is desolated by a display controller on a display panel..

Lamp for vehicle, and vehicle

A lamp for a vehicle includes: a lens; a first light source positioned at a rear side of the lens and configured to generate a first light; a first reflector configured to reflect the first light toward the lens; a second light source positioned at the rear side of the lens and configured to generate a second light; and a second reflector configured to reflect the second light toward the lens, wherein the first light source is configured to output the first light in a first direction, and the second light source is configured to output the second light in the first direction.. .

Systems and methodologies for controlling a vehicle light

A vehicle illumination system and method for controlling a vehicle light. The method includes receiving an input signal at a controller port; generating a control signal to activate the vehicle light based on both a rising and falling edge of the input signal in which the control signal activates an animation sequence when a falling edge is detected..

Occupant support device for a seat

An occupant support device (osd) for a seat, comprises a flexible membrane having a first end and a second end. The flexible membrane is coupleable to a seat proximate the first end and the second end of the flexible membrane.

Power consumption control device

A power consumption control device includes: a storage battery configured to supply power to an electric motor of a plug-in electric motor vehicle; a heating unit configured to heat the storage battery using heat generated through current flowing; a power conversion unit configured to convert power supplied from an external power supply; an estimation unit configured to estimate a change in effective capacity of the storage battery when the heating unit generates heat through current flowing by the power supplied from the external power supply and raises the temperature of the storage battery to a target temperature, based on an effective capacity corresponding to the temperature and soc of the storage battery; and a controller configured to control usage of the power converted by the power conversion unit according to the change of the effective capacity, estimated by the estimation unit.. .

Vehicle power supply apparatus

A vehicle power supply apparatus includes a motor generator, a first electricity storage device, a second electricity storage device, a switch, a switch controller, and an electricity storage device determiner. The switch controller is configured to cause the first cutoff state of the switch, switchable between a first electrically conductive state that allows the motor generator and the first electricity storage device to be coupled to each other and a first cutoff state that allows the motor generator and the first electricity storage device to be isolated from each other, to be maintained in a situation where the first electricity storage device discharges beyond a threshold, on a condition that the switch is switched to the first cutoff state in accordance with controlling of the motor generator into a powering state and the second electricity storage device is determined as being in an abnormal state..

Vehicle and control method therefor

When a vehicle is traveling in a state in which an abnormality has occurred in a second resolver, a pwm control unit periodically calculates an estimated electrical angle value of a second motor generator and generates a control command for an inverter using the estimated electrical angle value. The estimated electrical angle value in each cycle can be calculated by correcting an electrical angle estimation error with respect to a sum of an estimated rotation angle change value between cycles and an estimated electrical angle value in a previous cycle.

Smart active mount

A smart active mount apparatus configured for removing a complicated wiring for connecting a controller, a mount, and an engine ecu, a vacuum negative pressure hose, and a controller may include an insulator disposed in a case to define a liquid chamber; a lower orifice plate disposed in the case to partition the liquid chamber into upper and lower liquid chamber; an upper orifice plate disposed above the lower orifice plate; a membrane disposed between the lower and upper orifice plates; a diaphragm disposed under the lower orifice plate, an air chamber defined between the membrane and the lower orifice plate; a solenoid valve connected to the air chamber; and a generator disposed to the diaphragm, the generator generating electrical energy by movement or deformation of the diaphragm to supply the electrical energy as actuating power of the solenoid valve.. .

Cold formed laminates

The principles and embodiments of the present disclosure relate generally to complexly curved laminates made from a complexly curved substrate and a flat substrate, such as automotive window glazings, and methods of cold forming complexly-curved glass products from a curved substrate and a flat substrate. In one or more embodiments, the laminate includes first complexly-curved glass substrate with a first surface and a second surface opposite the first surface, a second complexly-curved glass substrate with a third surface and a fourth surface opposite the third surface with a thickness therebetween; and a polymer interlayer affixed to the second convex surface and third surface, wherein the third surface and fourth surface have compressive stress values respectively that differ such that the fourth surface has as compressive stress value that is greater than the compressive stress value of the third surface..

Roll control vehicle

A roll control apparatus for a vehicle which comprises front wheel side and rear wheel side active stabilizer devices and a control unit that is configured to control the stabilizer devices, to calculate a target anti-roll moment, to determine optimum control gains of electric actuators of the stabilizer devices among pre-stored control gains based on a vehicle speed and a frequency of change in a roll angle of a vehicle body, and to control the electric actuators so that a sum of anti-roll moments generated by the front wheel side and rear wheel side active stabilizer devices becomes the target anti-roll moment and control gains of the electric actuators become the optimum control gains.. .

Ultra super single tire for heavy duty

An ultra super single tire for heavy duty includes a tread that contacts the road surface; a carcass that constitutes the skeleton of the tire; and a belt layer that is disposed between the tread and the carcass, in which the belt layer is composed of a first belt to a fourth belt that are laminated sequentially from the carcass toward the tread, the first belt includes an extender belt, and the second belt is a wide spiral coil belt. Thus, an excessive increase in weight, the occurrence of excessive heat generation, and deterioration of durability can be prevented, while enhancing the ground contact length at the ground contacting center, and further enhancing the durability at belt layer edges..

Method for setting up and operating an inkjet printing machine for a print job

A method for setting up and carrying out a print job on an inkjet printing machine having print heads and a thermal dryer includes printing onto a substrate using water-based black and chromatic inks. First test prints of a first test chart with different area coverage test patches are generated on the substrate using black ink, thermally drying the first test prints at different temperatures and evaluating dried first test prints to determine a dryer operating temperature during the print job.

Thermal head and thermal printer

A thermal head includes: a head base body including a substrate and a plurality of heat generating sections disposed on the substrate; connection portions which are electrically connected to the head base; a connection member which is electrically connected to the connection portions; and a first cover member which covers the connection portions, the first cover member including a plurality of protruding portions provided on an upper surface of the first cover member at predetermined intervals in a main scanning direction.. .

Thermal head and thermal printer

A thermal head includes: a substrate; a heat generating section which is disposed on the substrate; a plurality of driving ics including first and second driving ics which are disposed on the substrate and electrically coupled to the heat generating section; and a cover member covering the first and second driving ics. The cover member is disposed in an inter-driving ic region between the first driving ic and the second driving ic and above and below the inter-driving ic region, and includes a first void..

Recording device and recording method

A recording device includes a recording head having multiple ejection port columns each configured such that multiple ejection ports for ink ejection are arrayed in a predetermined direction. The multiple ejection port columns are arranged in a crossing direction crossing the predetermined direction.

Fluid ejection device, printhead, printer, and manufacturing the ejection device

Ejection device for fluid, comprising a solid body including: first semiconductor body including a chamber for containing the fluid, an ejection nozzle in fluid connection with the chamber, and an actuator operatively connected to the chamber to generate, in use, one or more pressure waves in the fluid such as to cause ejection of the fluid from the ejection nozzle; and a second semiconductor body including a channel for feeding the fluid to the chamber, coupled to the first semiconductor body, in such a way that the channel is in fluid connection with the chamber. The second semiconductor body integrates a damping cavity over which extends a damping membrane, the damping cavity and the damping membrane extending laterally to the channel for feeding the fluid..

Recording apparatus and recording method

A recording apparatus includes a recording head having a plurality of recording elements configured to generate energy for discharging ink, a first heating element configured to heat ink in the vicinity of one of said recording elements positioned at a first position, insufficiently to discharge ink, and a second heating element positioned at a second position different from the first position, which are arranged on a same substrate, a heating control unit configured to control the heating operation of the ink by driving the first and the second heating elements by applying voltage to the first and the second heating elements, and a recording control unit configured to control the recording operation by driving the plurality of recording elements, wherein the heating control unit is configured to control the heating operation to drive the first heating element and the second heating element at timings different from each other.. .

Center drum type gravure printing apparatus, and gravure printing method and manufacturing printed matter using said apparatus

Provided are a center drum type gravure printing apparatus comprising a plurality of gravure plate cylinders, which generates no volatile organic compound, eliminates printing misregistration, requires only a small installation space, and is suitable for performing multi-color printing, and a gravure printing method and a method of manufacturing a printed matter, which use the center drum type gravure printing apparatus. The center drum type gravure printing apparatus, comprises: a center drum; a guiding means for guiding a material to be printed, the guiding means being configured to introduce the material to be printed to a drum surface of the center drum, and being configured to deliver the material to be printed from the drum surface; a plurality of gravure plate cylinders arranged, each of the plurality of gravure plate cylinders having a plate surface with gravure cells; an ink chamber arranged to the plate surface of the each of the plurality of gravure plate cylinders so as to supply an electron beam curable ink to the gravure cells of the each of the plurality of gravure plate cylinders; and an electron beam irradiation means for curing the ink transferred from the gravure cells supplied with the ink to the material to be printed, the electron beam irradiation means being positioned on a downstream side of the material to be printed, which is being guided..

Laminate film for temporary bonding, methods for producing substrate workpiece and laminate substrate workpiece using the laminate film for temporary bonding, and producing semiconductor device using the same

The present invention provides a laminate film for temporary bonding which is excellent in heat resistance, capable of providing a flat film even at the periphery of a substrate, and capable of making a semiconductor circuit formation substrate and a support substrate or a support film layer adhere to each other with one type of adhesive, and which can be peeled off at room temperature under mild conditions. The present invention provides a laminate film for temporary bonding, including at least three layers of (a) a protective film layer, (b) an adhesive layer, and (c) a support film layer, wherein the adhesive layer (b) contains at least a siloxane polymer represented by a specific general formula or a compound represented by a specific general formula..

Gypsum fiber roof panel with angled edge for accommodating environmentally-induced expansion

A gypsum fiber roofing panel with an angled edge for accommodating environmentally-induced expansion is provided, including a homogeneous body formed from a slurry of gypsum and reinforcing fibers having a face panel, a back panel, and a plurality of side edges, each side edge having an angle relative to a plane defined by the adjacent face panel in the range of 81-87° for accommodating environmentally-induced expansion relative to adjacent panels upon installation on a roof.. .

Apparatus for point of service manufacture of custom headwear

Apparatus is provided for point of service manufacture of custom headwear for a subject. The apparatus comprises capture apparatus disposed at a physical location for capturing three dimensional digital data of the head of the subject and generating a three-dimensional digital data file representative of said head; an additive manufacture device located at the physical location; and a processor.

Apparatus for point of service manufacture of custom cranial remodeling devices

Apparatus provides point of service to manufacture a custom cranial remodeling device for correction of cranial deformity of a subject. The apparatus comprises capture apparatus disposed at a physical location for capturing three dimensional digital data of the head of the subject and generating a three-dimensional digital data file representative of the head and an additive manufacture device located at the physical location.

Method of manufacture of custom headwear by additive manufacturing

A method for fabricating a custom headwear for a subject is described. The method comprises generating a three-dimensional head data file for the subject; identifying predetermined reference points on the head; automatically selective utilizing the predetermined reference points to calculate contour lines on the head; automatically generating a headwear data file; juxtaposing the headwear represented by the headwear data file with the head represented by the three-dimensional head data file having the contour lines thereon; utilizing the headwear data file to generate a shape for a desired headwear, the shape having an interior surface to contact the head and an outer surface; projecting lines outward from the contour lines to the outer surface; and utilizing the projected lines to establish headwear contour lines for the custom headwear..

Method of manufacture of custom cranial remodeling devices by additive manufacturing

A method for fabricating a custom cranial remodeling device for correction of cranial deformities in a subject is described. The method comprises generating a three-dimensional head data file for the subject; identifying predetermined reference points on the head; automatically selective utilizing the predetermined reference points to calculate contour lines on the head; automatically generating a modified head shape data file; juxtaposing the modified head shape with the head represented by the three-dimensional head data file having the contour lines thereon; utilizing the modified head shape data file to generate a shape for a desired custom cranial remodeling device, the shape having an interior surface to contact the head and an outer surface; projecting lines outward from the contour lines to the outer surface; and utilizing the projected lines to establish cranial remodeling device contour lines for the custom cranial remodeling device..

Universal part gripper using 3-d printed mounting plate

A generic holder includes a generic holder plate and a 3-d insert plate. The 3-d insert plate contains locating features mirrored to the backside of the part to be printed and vacuum grippers to secure the part in the insert plate.

Method and system for compliant press-fit tray table

A thermoplastic homogenous tray table assembly includes a top cover and a bottom cover. An injection molded thermoplastic composite reinforced frame assembly with a plurality of compliant press-fit device receptacle apertures is homogenously chemically bonded to the top cover, and a similar frame is formed for the bottom cover.

Method for producing shaped bodies

A generative process for the manufacture of three-dimensional mouldings is characterized by constructing the moulding stepwise by site-specific delivery of a structure-forming material in liquid form, where a second material is additionally delivered as a supportive material into regions which are intended to remain free from the structure-forming material, and is removed once the structure-forming material has been solidified. The supportive material exhibits low shrinkage upon cooling and is particularly stable in the cooled state and further exhibits low surface roughness..

Three-dimensional object modeling device, molding three-dimensional object, and control program for three-dimensional object modeling device

A three-dimensional object modeling device includes: a recording head including a plurality of nozzles each of which discharges a droplet of the ink; a memory that pre-stores nozzle data for each of the plurality of nozzles, the nozzle data corresponding to a volume or an amount of increase or decrease in the volume of the discharged droplet after solidified; a modeling data generator that generates modeling data for modeling the three-dimensional object; and a discharge data generator that generates ink discharge data for instructing discharge of the ink droplet for each of the plurality of nozzles in accordance with the pre-stored nozzle data based on the generated modeling data so that a total height of a dot in a direction of layering the dot is uniformalized.. .

Three-dimensional object modeling device, molding three-dimensional object, and control program for three-dimensional object modeling device

A three-dimensional object modeling device includes a model data generator that generates model data including a color of the three-dimensional object; a region determiner that determines a color region to be colored by the coloring ink, and a model region that is inwardly of the color region and to be modeled by the modeling ink, based on the generated model data; a first discharge data generator that generates discharge data of the modeling ink in the model region; a second discharge data generator that generates discharge data of the coloring ink while limiting formation of the dot with the coloring ink in the color region to less than or equal to a unit thickness of modeling using the coloring ink and the modeling ink; and a processing controller that causes the modeling ink and the coloring ink to be discharged using the generated discharge data.. .

Three-dimensional object modeling device, molding three-dimensional object, and control program for three-dimensional object modeling device

A method of molding a three-dimensional object, the method including: generating modeling data for the three-dimensional object; determining a region to be modeled by layering the dot using the modeling ink based on the modeling data; determines a color region to be colored by discharge of the coloring ink on a surface of a set of the layered dot with the modeling ink, based on the modeling data to reduce a difference in depth in a normal direction of a surface of the three-dimensional object; generating modeling ink discharge data for discharging the modeling ink, and coloring ink discharge data for discharging the coloring ink; and causing the modeling ink and the coloring ink to be discharged in accordance the discharge data of the modeling ink and the coloring ink, and performing modeling and coloring of the three-dimensional object.. .

Three-dimensional object property determination

In one example, a method comprises receiving data representing a first property of a three-dimensional object generated by a print apparatus, the data having been determined by measurement of the object. A difference between the data representing a first property and predetermined data may be determined, and, based on the difference, an estimate of a second property of the object may be determined..

Planetary roller extruder

A planetary roller extruder. The abstract of the disclosure is submitted herewith as required by 37 c.f.r.

Microbubble creating method using a forming machine

A microbubble creating method using a forming machine for creating microbubbles by: installed a microbubble generating member in a mold, feed screw or barrel for enabling a perforated tip of the microbubble generating member to be surrounded by the applied fluid polymer so that when a high pressure high temperature gas is delivered through the perforated tip of the microbubble generating member, microbubbles are created with well mixed with the fluid polymer, and the expected foamed polymer product is thus obtained after cooling.. .

Microbubble creating method using a forming machine

A microbubble creating method using a forming machine for creating microbubbles by: installed a microbubble generating member in a mold, feed screw or barrel for enabling a perforated tip of the microbubble generating member to be surrounded by the applied fluid polymer so that when a high pressure high temperature gas is delivered through the perforated tip of the microbubble generating member, microbubbles are created with well mixed with the fluid polymer, and the expected foamed polymer product is thus obtained after cooling.. .

Fuel tank producing apparatus

Provided is a fuel tank producing apparatus capable of uniformly heating a tank container in a short period of time. The fuel tank producing apparatus includes a heat curing furnace for heating the tank container and a hot air generator for generating hot air.

Systems and methods for producing consumable powder

A consumable polymeric based powder mixture may include a plurality of polymeric based particles that have a unitary construction. At least about 80% of the plurality of polymeric based particles may further have a generally cylindrical shape.

Apparatus for general object holding during printing using multiple conformable gripper balls

A universal object holding mechanism for holding three-dimensional objects for printing thereon uses multiple conformable balls mounted within a pattern of holes in a two part back plate. The multiple conformable balls are pressed into an object which in turn is pressed against a datum surface that represents desired spacing away from print heads.

Real-time control system, real-time control device and system control method

A system controlling method according to an embodiment of the present invention comprises operating a plurality of agents having mutually independent processes using a shared memory; obtaining hardware control data for controlling one or more devices from each of references generated from the plurality of agents and stored in the shared memory; and transferring control signals according to the references to the one or more devices selected from the hardware control data.. .

Systems and methods for robotic path planning

Systems and methods for robotic path planning are disclosed. In some implementations of the present disclosure, a robot can generate a cost map associated with an environment of the robot.

Method of generating robot operation command and robot operation command generation device

A method of generating a robot operation command includes extracting a work command from an overall work flow; extracting, from a command definition database, a command definition corresponding to the extracted work command, the work command having been read; generating, by referring to the read work command, a set of unit jobs in which at least one work command is arranged in order, based on the extracted command definition; generating, for a plurality of unit jobs, a connecting job for causing a robot to be moved from an end position of a previous unit job to a start position of a subsequent unit job; and generating a robot operation command in which the unit jobs and the connecting job are continuous.. .

Gpos-connected real-time robot control system and real-time device control system using same

Provided is a real-time robot controlling system which includes a gpos (general purpose operation system); a rtos (real time operation system) operated on the gpos to drive a device controlling system; and one or more devices being controlled in hard real-time connected to the rtos in a real-time device controlling system, wherein the device controlling system providing a user interface to the gpos; performing real-time device control processes according to the interface input or time synchronization; and processing communication with the one or more devices according to the control processes.. .

Robot control device and robot system

A robot control device includes: a processor that is configured to execute computer-executable instructions so as to control a robot, wherein the processor is configured to: receive a first instruction from an operation device; display information regarding a target vibration frequency of a robot obtained based on vibration data indicating vibration of the robot in a certain time section on a display, when the processor receives the first instruction; set the target vibration frequency; generate a second control signal obtained by reducing the target vibration frequency from a first control signal based on the set target vibration frequency; and generate a driving signal to drive the robot based on the second control signal and output the driving signal.. .

Control device and robot system

A control device includes: a processor wherein the processor is configured to generate one or more second control signals obtained by reducing at least one frequency component from a first control signal, output one control signal among the first control signal and the one or more second control signals, receive an instruction indicating execution of a reduction in the frequency component, generate a driving signal for driving a robot based on the control signal output from the processor and output the driving signal, output the first control signal when a first condition including non-input of the instruction indicating the execution of the reduction in the frequency component is satisfied, and output the second control signal when a second condition including input of the instruction indicating the execution of the reduction in the frequency component is satisfied.. .

Control device and robot system

A control device includes a processor wherein the processor is configured to: receive designation of one or more frequency components, generate one or more second control signals obtained by reducing at least one of the frequency components from a first control signal, generate one or more third control signals obtained using two control signals among the first control signal and the one or more second control signals, output one control signal among the first control signal, the one or more second control signals, and the one or more third control signals, and generate and output a driving signal to drive a robot based on the one control signal.. .

Control device, control system, robot, and robot system

A control device includes: a processor that is configured to execute computer-executable instructions so as to control a robot, wherein the processor is configured to: generate a second control signal by reducing at least one of frequency components obtained based on an output of a first detector which is installed in a portion vibrated by a robot and detects vibration from a first control signal for driving the robot, and wherein the portion is different from the robot and an end effector installed in the robot.. .

Robot and gear unit

A robot includes a first member, a second member provided rotatably with respect to the first member, a gearing that transmits drive power from one side to the other side of the first member and the second member, the gearing includes an internal gear, an external gear having a flexible barrel portion in a tubular shape with an opening portion in an end part, and rotating about a rotation axis relative to the internal gear, and a wave generator, the wave generator includes a cam having a non-circular outer circumferential surface, and a bearing including an inner ring, an outer ring, and a plurality of balls, the first member includes a counter body provided to face the end part on the opening portion side of the barrel portion, and a first seal member is provided between the outer ring and the counter body.. .

Telescoping pole with grabbing member

A telescoping pole is provided with means for attaching a series of removable grabber attachments at one end. One such attachment resembles the head of a hoe, where a flat blade member is attached to a shaft, so that the flat blade member is oriented in a generally perpendicular relation to the longitudinal axis of the telescoping pole.

Automated drywall sanding system and method

An automated sanding system that includes a robotic arm and a sanding end effector coupled at the distal end of the robotic arm, with the sanding end effector configured to sand a target surface. The system can further include a computing device executing a computational planner that generates instructions for driving the sanding end effector and robotic arm to perform at least one sanding task that at least includes the sanding end effector sanding a target surface, the generating based at least in part on obtained target surface data; and drives the end effector and robotic arm to perform the at least one sanding task..

Method and device for determining a vibration amplitude of a tool

A method for determining a vibration amplitude of a tool, includes the steps of: generating a light beam of a light barrier with a transmitter for generating the light beam and a receiver for detecting a light intensity of the light beam; generating a receiver signal on the basis of a light intensity of the light beam that is detected by the receiver of the light barrier; positioning a tool tip of the tool in the light beam; causing the tool to vibrate; determining the vibration amplitude of the tool from a modulation of the receiver signal brought about by the vibration of the tool.. .

Control device for machine tool performing oscillation cutting

A control part of a control device includes a learning controller and a learning determination part. The learning controller performs learning control in which a correction amount of a resultant command is obtained, based on an oscillation phase obtained from an oscillation command and the resultant command, and the correction amount is added to the resultant command.

Method and system for machining

A method and a system for machining a work piece by a machining tool are provided. The method includes relatively moving the machining tool against the work piece to apply machining feeds therebetween.

Device for additive manufacturing of a turbomachinery part by direct metal deposition onto a substrate

A device for the additive manufacturing of a turbomachinery part by direct metal deposition onto a substrate comprising: a source of metallic material; a source of energy configured to produce molten metal from the metallic material produced from the source of metallic material; a substrate; a mold arranged on the substrate and equipped with at least one opening, in order to allow a localized deposition of molten metal onto the substrate, the mold comprising a magnetic material; and a substrate support arranged under the substrate, the support being configured to generate an electromagnetic force allowing the mold to be drawn towards the substrate.. .

Scan strategies for efficient utilization of laser arrays in direct metal laser melting (dmlm)

An additive manufacturing system configured to manufacture a component including scan strategies for efficient utilization of one or more laser arrays. The additive manufacturing system includes at least one laser device, each configured as a laser array, and a build platform.

Single-position sequential laser welding system

Methods and systems for sequentially laser welding terminal tabs of a battery cell to corresponding terminal tabs of a busbar are described using a single laser position and path. The terminal tabs of a battery cell are aligned in contact with terminal tabs of a busbar.

Control device and controlling the laser beam deflection

A method and a control device for deflection of a laser beam for laser-based additive manufacturing processes includes first and second orthogonally rotatable mirrors designed to reflect the laser beam and guide the laser beam to an irradiation field. The first mirror and the second mirror are secured on respective first and second shafts, with the first mirror performing a continuous first vibration with a first frequency, and the second mirror performing a continuous second vibration with a second frequency different from the first frequency and/or with a phase difference with respect to the first vibration.

Resistance spot welding method

A stored time variation curve and cumulative amount of heat generated of each step are each used as a target. In the case where a time variation of an instantaneous amount of heat generated per unit volume differs from the time variation curve in any of the steps, a current passage amount is controlled in order to compensate for the difference within a remaining welding time in the step so that a cumulative amount of heat generated per unit volume in actual welding matches the stored cumulative amount of heat generated in the test welding.

Plasma welding method

One object of the present invention is to provide a plasma welding method capable of performing plasma welding while restraining initial investment in a welding device, and the present invention provide a plasma welding method includes a pilot arc generation step in which a pilot arc is generated between the electrode and the insert chip by supplying a first pilot gas which is easily converted into a plasma state between the electrode and the insert chip while supplying a shield gas between the insert chip and the shield cap; and a first welding step in which, after the pilot arc generation step, a main arc is generated between the electrode and the workpiece by electrically disconnecting the plus terminal and the insert chip by the first selector switch while supplying the first pilot gas and the shield gas.. .

Variable switching frequency power supply for plasma cutters and plasma arc welders

A power supply, for a plasma cutter or a plasma arc welder, having a variable switching frequency and method of operating the power supply is generally disclosed. The power supply includes a switch for setting the switching frequency and a chopper control circuit for determining current output from the power supply, determining an operating frequency based on the determined current output and setting the switching frequency based on the determined operating frequency..

Heat manipulation and seam tracking of weaved welds

An arc welder produces a weave pattern between workpieces. Each weld run comprises a center portion including a joining region between the workpieces and edge regions spaced apart from the joining region.

Rotating machine tool and process for cutting gearwheels with asymmetrical teeth

A rotating cutting tool to cut asymmetrical teeth in a gearwheel in which each tooth (21) has an active flank (a) with a convex profile meshing with the profile of a tooth of an opposing gearwheel meshing with the gearwheel and a secondary concave flank (s), provided with teeth (11) on a generally helical path which extends from one side to the other with respect to a median cross-section (m-m) of the tool which is intended to be intersected by the radius rp of the gearwheel which is at right angles to the axis of rotation of the tool working on the gearwheel to cut its teeth. The helical teeth have a first flank (ca) which is intended to cut the said active flank (a) of the gearwheel teeth and a second flank (cs) intended to cut the secondary flank (s), the pitch (p1) between the first flank (ca) of the helical teeth being constant and the pitch (p2) of the second flank of the teeth being smaller than the pitch (p1)..

Additive manufacturing using a mobile build volume

The present disclosure generally relates to additive manufacturing systems and methods on a large-scale format. One aspect involves a build unit that can be moved around in three dimensions by a positioning system, building separate portions of a large object.

Large scale additive machine

The present disclosure generally relates to additive manufacturing systems and methods on a large-scale format. One aspect involves a build unit that can be moved around in three dimensions by a positioning system, building separate portions of a large object.

Optical fiducial generation for galvanometric scanner calibration

An apparatus includes an optical source situated to produce a fiducial source beam, and an optical fiducial pattern generator situated to produce with the fiducial source beam at least one transient optical fiducial on a laser processing target that is in a field of view of a laser scanner situated to scan a laser processing beam across the laser processing target, so that a positioning of the laser processing beam on the laser processing target becomes adjustable relative to the at least one transient optical fiducial.. .

Additive manufacturing with laser energy recycling

Additive manufacturing systems, area scanning laser systems, and methods for performing an additive manufacturing process are provided. An exemplary additive manufacturing system includes a laser generation device for producing a laser beam.

Rolling bending method and rolling bending apparatus

A steel strip is fed and compressed between a driving roller and a compression roller to generate a stress greater than a yield stress in the steel strip and to elongate one periphery portion of the steel strip, which is on one side, more than the other periphery portion of the steel strip, which is on the other side, in a sending direction. The compression roller includes a first contact portion and a second contact portion.

Automated drywall painting system and method

An automated painting system that includes a robotic arm and a painting end effector coupled at a distal end of the robotic arm, with the painting end effector configured to apply paint to a target surface. The painting system can also include a computing device executing a computational planner that: generates instructions for driving the painting end effector and robotic arm to perform at least one painting task that includes applying paint, via the painting the end effector, to a plurality of drywall pieces, the generating based at least in part on obtained target surface data; and drives the end effector and robotic arm to perform the at least one painting task..

Passive electrostatic co2 composite spray applicator

An electrostatic spray application apparatus and method for producing an electrostatically charged and homogeneous co2 composite spray mixture containing an additive and simultaneously projecting at a substrate surface. The spray mixture is formed in the space between co2 and additive mixing nozzles and a substrate surface.

Air cooled rotating disc and mill assembly for reducing machines

A reducing machine having an air cooled cutting discs is disclosed. The air cooled discs have cutting surfaces on both sides.

Sorting biological and non-biological moieties using magnetic levitation

Systems and methods for levitating populations of moieties, cells, or other such units using one or more magnets in a microfluidic environment are provided. These systems and methods may be used to, for example, separate or sort heterogeneous populations of the units from one another, to assembly a multi-unit assembly during the levitating of the units, and to evaluate samples at the point of care in real-time.

Fcc high efficiency partial burn regenerator

A process for combusting coke from catalyst in partial burn mode is disclosed. The partial burn regenerator runs deprived of oxygen such that the flue gas will contain a fair amount of carbon monoxide.

Precatalysts and process for the metal-free functionalization of sp2 carbons using the same

Precatalysts of formula i and iv, and processes for the functionalization of sp2-carbons using the same are described herein. The precatalysts comprise a fluoroborate salt protected intramolecular frustrated lewis pair (flp).

Heterogeneous core@shell photocatalyst, manufacturing method therefore and articles comprising photocatalyst

A heterogeneous core@shell photocatalyst having a combination of properties that include rapid adsorption and effective decomposition with respect to various substances is provided. This core@shell photocatalyst comprises a conventional photocatalyst core coated with an adsorbent surface layer (in the nanometer size range).

Powdered titanium oxide, the production thereof, and use thereof

A powdered catalyst material on a titanium oxide basis. The powdered catalyst material includes a combined content of at least 90 wt.-% of a hydrated titanium oxide having the general formula tio(2-x)(oh)2x, with 0<x≤1, (calculated as tio2), and a silicon dioxide and hydrated precursors of the silicon dioxide (calculated as sio2).

Binderless zeolitic adsorbents and methods for producing binderless zeolitic adsorbents

The present invention generally relates to binderless zeolitic adsorbents and methods for making the binderless adsorbents. More particularly, the invention relates to fau type binderless zeolitic adsorbents and methods for making the fau type binderless adsorbents.

Binderless zeolitic adsorbents and methods for producing binderless zeolitic adsorbents

The present invention generally relates to binderless zeolitic adsorbents and methods for making the binderless adsorbents. More particularly, the invention relates to fau type binderless zeolitic adsorbents and methods for making the fau type binderless adsorbents.

Systems and methods for a cooled nitric oxide generator

Systems and methods for a nitric oxide (no) generation system are provided. In particular, the present disclosure provide an no generation system that is configured to be cooled to maintain an no generator of the system at or below temperatures safe for patient use and contact.

Air-cooled heat exchangers

A plant or refinery may include equipment such as reactors, heaters, heat exchangers, regenerators, separators, or the like. Types of heat exchangers include shell and tube, plate, plate and shell, plate fin, air cooled, wetted-surface air cooled, or the like.

Apparatus for increasing gas components in a fluid

An apparatus for increasing gas components in a fluid uses a controller connected to a network and client device for remote control of fluid flow rates, magnet field intensity, and pressure of fluid based on preset parameters. Conductive wire coiled around a magnet fluid treatment device generates a bidirectional magnetic flux to magnetically treat fluid in the conduit at an entry pressure.

Apparatus for increasing gas components in a fluid

An apparatus for increasing gas components in a fluid uses a controller connected to a network and client device for remote control of fluid flow rates, magnet field intensity, and pressure of fluid based on preset parameters. Conductive wire coiled around a magnet fluid treatment device generates a bidirectional magnetic flux to magnetically treat fluid in the conduit at an entry pressure.

Detecting and correcting problems in liquid lifting in heat exchangers

A plant or refinery may include equipment such as reactors, heaters, heat exchangers, regenerators, separators, or the like. Types of heat exchangers include shell and tube, plate, plate and shell, plate fin, air cooled, wetted-surface air cooled, or the like.

Microfluidic droplet generator with controlled break-up mechanism

Droplet generation devices and systems that parallelize droplet generation devices are provided. The droplet generation devices can include a symmetric block-and-break system and a tapered droplet generation zone.

Reaction-regeneration device and process for alkane dehydrogenation to alkene

A reaction-regeneration device for catalytic dehydrogenation or/and catalytic cracking of alkanes comprises a reaction device and a regeneration device. The reaction device comprises a reactor and a disengager, and the disengager is located at an upper part of the reactor.

Asc/dec with rear-concentrated exotherm generation

A catalyst article including a substrate with an inlet side and an outlet side, a first zone and a second zone, where the first zone includes an ammonia slip catalyst (asc) comprising a platinum group metal on a support and a first scr catalyst; where the second zone includes a catalyst selected from the group consisting of a diesel oxidation catalyst (doc) and a diesel exotherm catalyst (dec); and where the first zone is located upstream of the second zone. The first zone may include a bottom layer with a blend of: (1) the platinum group metal on a support and (2) the first scr catalyst; and a top layer comprising a second scr catalyst, the top layer located over the bottom layer..

Combustion system

A combustion system operated at low cost is provided. A combustion system 1 includes a combustion device 10 that burns fuel, an exhaust line l1 through which exhaust gas flows, the exhaust gas being generated through combustion of the fuel in the combustion device 10, an air preheater 30 that is disposed in the exhaust line l1 and that recovers heat from the exhaust gas, and a denitration device 40 that is disposed in the exhaust line l1 and that removes nitrogen oxide from the exhaust gas using a denitration catalyst.

Sorbents for the oxidation and removal of mercury

A promoted activated carbon sorbent is described that is highly effective for the removal of mercury from flue gas streams. The sorbent comprises a new modified carbon form containing reactive forms of halogen and halides.

Use of a peak-dampening capacitor to improve adsorber separation performance

This invention uses a fixed-bed adsorber, interchangeably called a capacitor herein, to process the product stream coming out of a regenerable adsorption system such as a temperature swing adsorption system (tsa) or pressure swing adsorption system (psa). The fluid stream coming out of this fixed-bed capacitor will have a more uniform composition than the one entering the adsorption system or the capacitor.

Mixer truck water spray bar

A mixer truck water spray bar for suppression of dust clouds is disclosed. The mixer truck water spray bar generally includes an entrance chute configured to receive water from the drum via the mixer chute that is removably attachable to the mixer chute and a manifold attached to the entrance chute that is oriented substantially perpendicular to the entrance chute and is configured to receive water from the entrance chute via an entrance opening and comprises a plurality of apertures configured to externally distribute water received through the entrance opening through the apertures without the use of a pump..

Filter device for an extractor device

A filter device for an extractor device includes at least one connecting unit configured to connect to at least one filter element. The filter device also includes an oscillating unit with at least one exciter element that generates oscillations which act on the filter element at least for cleaning of the filter element.

Exhaust purification device, internal combustion device, and power generation device

There is provided an exhaust purification device including a particulate filter configured to collect particulates contained in an exhaust gas, an oxidation catalyst disposed in a front stage of the particulate filter and configured to have a carrier partially or entirely made of a material which absorbs a microwave, a housing in which the particulate filter and the oxidation catalyst are arranged, and a microwave generator configured to generate a microwave to be irradiated onto the oxidation catalyst in a direction to which the exhaust gas flows.. .

Process for making high efficiency synthetic filter media

The present invention is generally related to a high capacity, high efficiency nonwoven filtration media comprising a gradient pore structure. In particular, the filtration media can comprise thermoplastic synthetic microfibers, fibrillated fibers, staple fibers, and a binder.

Process for utilizing a high efficiency synthetic filter media

The present invention is generally related to a high capacity, high efficiency nonwoven filtration media comprising a gradient pore structure. In particular, the filtration media can comprise thermoplastic synthetic microfibers, fibrillated fibers, staple fibers, and a binder.

High efficiency synthetic filter media

The present invention is generally related to a high capacity, high efficiency nonwoven filtration media comprising a gradient pore structure. In particular, the filtration media can comprise thermoplastic synthetic microfibers, fibrillated fibers, staple fibers, and a binder.

A duct for use in a system for separating particles suspended in a fluid, and a designing such duct

There are provided a duct for use in a system for separating particles suspended in a fluid and a method for designing such duct. The duct comprises at least one trapping-bay portion having a main channel extending along a curved central line defining a fluid flow direction and one or more trapping bays configured for trapping at least a part of the particles and coextensive with the main channel along the central line.

Building blocks with lights for guided assembly

Techniques are disclosed for assembling a set of connectable building blocks by using a computing device to access, from wireless communication elements in each block, general information regarding the set of blocks and specific information regarding at least one block of the set that is placed on a conducting mat and each block of the set that is connected to the at least one block on the conducting mat. Structural information regarding structures for assembly using the blocks is accessed based on the general and specific information.

System of improving neuroplasticity and recovery during occupational, physical, and related therapies

The present invention relates to generally to a system for improving neuroplasticity and recovery for a patient in need thereof.. .

Personalized user interface based on in-application behavior

Methods and systems to provide a user interface to access games available for a user account. Selection of a game for game play is detected at the user interface and, in response, a game play is initiated.

System and placement marketing

A system for placement marketing includes a remote server, at least one message provider and at least one portable device. The remote server includes a memory, a data analyzer module, a data classifying module, a combination type generator and a first combination type game module.

Computer-readable recording medium and system

Provided is a game program in which a region attribute of at least one region, among a plurality of regions included in a game field, is changed during a competition game in accordance with the progression state of the game, an event is generated during the progress of the game, and the event is progressed in accordance with the number of regions having a predetermined region attribute or the area of the region.. .

Management of streaming video data

User action data characterizing action by a player in a game environment executing at a user client is received at a server. The game environment is created by the user client separate from the server.

Game program, game terminal device, and game progress control method

Provided is a game program causing a portable computer capable of wirelessly communicating with another computer positioned in a communicable range to realize a function of controlling progress of a video game using a first game medium possessed by a user, the game program causing the computer to realize a reception function of receiving information regarding a second game medium from the another computer through wireless communication, and a generation function of generating a third game medium based on the first game medium and the second game medium in accordance with establishment of a generation condition.. .

A smart toy platform

The present invention relates to a smart toy platform, which provides various interactive games via an application installed in a smart device and basically comprises at least one object, at least one light source which is provided in each object and which emits infrared radiation, at least one electronic circuit, at least one board on which objects are placed, a plurality of sensors which are located on the board, at least one analog-digital converter which enables to convert. The analog data coining from the sensor into digital data, at least one controller which is adapted to control the digital data coming from the analog-digital converter and to generate the position data of each object on the board, at least one data communication unit which is located on the board and which enables the data generated by the controller to be transmitted to a smart device..

Skateboard for maintaining multiple cruising speeds

A method of operating an electric skateboard includes manually moving the electric skateboard forward without engaging an electric motor, then engaging a pressure sensor on the electric skateboard to output a pressure signal to a controller on the electric skateboard. The controller then generates a control signal to the electric motor corresponding to a first cruising torque.

Physical therapy management system

A physical therapy management system including a motion sensor mounted to a user's leg brace to sense and wirelessly transmit movement of the leg when the user is performing a prescribed exercise therapy routine. An app on the user's computing device receives the sensor motion data and compares the patient's exercise performance to the patient's therapy prescription.

System and networking fitness machines

A system and method for networking fitness machines for allowing a fitness trainer or instructor to control various settings for a plurality of exercise machines simultaneously, and further for allowing an individual user and/or trainer to modify the settings of an individual exercise machine. The system and method for networking fitness machines generally includes a trainer remote control device, one or more machine-mounted onboard trainer controllers, and a machine-mounted onboard user controller.

Golf swing training device

An easily assembled and disassembled portable golf swing training device includes plural interconnected elongated, linear rods and arms for the development of proper golf club takeaway, backswing and downswing mechanics. The position of the golf club during the swing is compared with generally accepted swing parameters, and club positions not within acceptable limits are evidenced by easily detected golf club contact with one or more of the device's aims which are all adjustable in length and position depending upon individual golfer characteristics, and which are pivotally mounted, padded and flexible to avoid injury as well as damage to the inventive device or to a golf club.

Exit speed generator

A training apparatus for use with a bat is provided. The training apparatus has a fastening portion releasably securable to a barrel of the bat and a resistance portion attached to the fastening portion such that the resistance portion extends past a barrel end of the bat when the training apparatus is secured to the barrel.

Sealed and ventilated receptacle

The present invention relates to a sealed and ventilated receptacle for storing equipment, such as firefighter turnout gear, that generally includes a base, at least one sidewall extending from the base, and a top wall that covers the opposite end of the sidewall. A sealable door may be positioned on the sidewall to access the inside of the receptacle and to prevent any contaminants from exiting the receptacle.

Methods for generating accurate radiation dose maps corrected for temporal and spatial changes arising in remote dosimetry applications

A method for generating a radiation dose map of a dosimeter indicating a spatial distribution of radiation dose imparted to the dosimeter. The corrected radiation dose map may be generated with the computer system by applying temporal correction factor and spatial correction factors to a measured radiation dose map, the corrected radiation dose map having pixel values associated with the measured radiation dose having been corrected for temporal effects caused by changes in the measure of radiation dose imparted to the dosimeter between the first time point and the second time point, and for spatial effects caused by the sensitivity of the dosimeter to radiation measurements as a function of the spatial dimension..

Mitigation of interplay effect in particle radiation therapy

The present disclosure relates to a new scan technique for particle radiation therapy that may be used for cancer treatment. One embodiment relates to a method of mitigating interplay effect in particle radiation therapy in a moving target including a period of movement, where the particle radiation therapy defines a planned dose in each spot of each layer of the moving target.

Positioning apparatus and positioning

A positioning apparatus automatically performs a patient positioning calculation at high speed and a positioning method. A positioning apparatus 40 has, as functional components, a drr image generation element 41 that generates the drr image based on the ct image data, an optimization element 43 that calculates the positional gap of the patient 57 by optimizing the fluoroscopic projection parameters; and an initial parameter adjustment element 42 that changes the initial position of the fluoroscopic projection parameters prior to optimization of fluoroscopic projection parameters with regard to the rotatable and translation of the ct image data relative to the optimization element 43..

Neutron capture therapy system and gamma ray detector for neutron capture therapy

A neutron capture therapy system includes a neutron ray generating unit, an irradiated body placing unit on which a patient (irradiated body) is placed, and a gamma ray detecting unit that detects gamma rays emitted from the patient (irradiated body). The gamma ray detecting unit includes an emission part that emits light or electrons as the gamma rays are incident thereon, an amplification part that amplifies and outputs the light or the electrons emitted from the emission part, a first neutron ray shielding part formed of a substance containing 6-lithium, and a second neutron ray shielding part formed of a light element.

System and volumetric modulated arc therapy

A system and method are provided for generating and delivering a volumetric modulated arc therapy (“vmat”) plan to a patient. In some aspects, the method includes receiving a representation of a patient comprising information related to target and non-target volumes of interest and generating an objective function based on the representation of the patient.

System and optogenetic therapy

Configurations are described for utilizing light-activated proteins within cell membranes and subcellular regions to assist with medical treatment paradigms, such as hypertension treatment via anatomically specific and temporally precise modulation of renal plexus activity. The invention provides for proteins, nucleic acids, vectors and methods for genetically targeted expression of light-sensitive proteins to specific cells or defined cell populations.

Magnetic stimulation device

A device for magnetic stimulation of body regions, including at least one magnetic coil connected to a stimulator which has a power element for generating electrical impulses to be applied to the at least one magnetic coil, so that the generated magnetic field can be induced in the body region, wherein a detection unit is provided for detecting metal elements within the body region. A measuring device is provided for detecting the electrical power received by the magnetic coil and a comparison device is provided for comparing the power with a predetermined limit value, the detection unit is connected to the stimulator, and the comparison unit is designed to automatically switch off the stimulator or reduce the power of the stimulator or of the power element of the stimulator in the event of the predetermined limit value being exceeded..

Apparatus and treating neurological disorders

An apparatus for treating neurological disorders comprising at least one electrode implantable in a patient's brain and a processing and stimulation device connected to the at least one electrode. The processing and stimulation device comprises at least one stimulation module adapted to generate a stimulation signal characterised by a plurality of parameters; at least one acquisition module adapted to acquire a signal characteristic of cerebral activity and determine its power in at least one frequency band; and at least one control module of at least one parameter of the stimulation signal as a function of the power of the signal characteristic of cerebral activity acquired, based on a transfer function having a saturating trend, wherein the transfer function is configured to set the at least one parameter of the stimulation signal differently dependent on a plurality of power ranges, by keeping the parameter within a predetermined stimulation range..

Advanced electrode array insertion and position management

A method, including sequentially activating a plurality of respective electrode pairs of an implanted cochlear implant, at least one of the electrodes of the respective electrode pairs being a respective electrode of an electrode array implanted in a cochlea, thereby generating respective localized electric fields, concurrently respectively measuring, for the plurality of activated respective electrode pairs, an electrical characteristic between the respective electrodes of the respective electrode pairs resulting from the respective localized electric fields, thereby obtaining a measurement set, determining, from the measurement set, a distance between the electrode array and a wall of the cochlea.. .

Tissue conduction velocity

A method includes acquiring a bipolar signal from a first electrode and a second electrode contacting a first location and a second location, respectively, in a heart of a living subject. The method further includes acquiring a unipolar signal from the first electrode while in contact with the first location, and deriving from the bipolar signal and the unipolar signal a point in time at which the first location is generating the unipolar signal.

Systems and methods for percutaneous body lumen drainage

The present disclosure relates generally to the field of devices and procedures for placement of a medical device between adjacent tissue structures. In particular, the present disclosure relates to systems and methods for percutaneous placement of a drainage stent between the gallbladder and gastric lumen (e.g., cholecystogastrostomy), or gallbladder and duodenum (cholecystoduodenostomy)..

Lamp with variable flickering frequency

A lamp for generating flickering at a selectable frequency corresponding to a desired human brainwave state comprises a base supporting a light source, a shade having a plurality of regularly circumferentially spaced apertures defined therein and a drive mechanism for rotating the shade about the light source. At least one speed control is coupled to the drive mechanism for controlling the rotational speed of the shade.

Silencer and artificial ventilator

A silencer having improved ease of maintenance and a small size and light weight and a respiratory assistance device. The silencer is provided to therapy equipment where pressurized air is generated by a blower, and the pressurized air is supplied to an airway of a patient from an attachment part attached to the patient, the silencer being inserted into a flow passage so as to reduce sound generated by the therapy equipment, the pressurized air being introduced from the blower to the patient through the flow passage.

Methods and high gas flow

Several methods of supporting respiratory function of a patient before, during and/or after a medical procedure are disclosed. In certain arrangements, supporting respiratory function while a patient is under general anaesthesia can include providing a high gas flow a high gas flow that is greater than 15 l/min while the patient is under general anaesthesia.

Atomizer and electronic cigarette having same

An atomizer with adjustable air intake quantity is disclosed including: an atomizer body, having a liquid storage chamber formed therein for storing tobacco liquid; an aerosol generator, configured for aerosolizing the tobacco liquid from the liquid storage chamber to generate an aerosol; at least one air inlet, formed on the atomizer body; an air pipe, disposed inside of the atomizer body and configured for conducting the aerosol to flow along the air pipe; the air inlet being in communication with the air pipe; and an adjusting cover, connected with the atomizer body by a thread to cover the air inlet; the adjusting cover is configured for being rotated to move up and down along axial direction of the atomizer body, to adjust a clearance between an edge of the adjusting cover and the atomizer body.. .

Pressure sensing ventricular assist devices and methods of use

The invention generally relates to heart pump systems. In some embodiments, a pressure sensor is provided with a heart pump, either at the inflow or the outflow of the blood pump.

Adjusting pump protocol based on irregular heart rhythm

The present invention generally relates to heart treatment systems. In some aspects, methods and systems are provided for facilitating communication between implanted devices.

Communication methods and architecture for heart treatment systems

The present invention generally relates to heart treatment systems. In some aspects, methods and systems are provided for facilitating communication between implanted devices.

Absorbable iron-based alloy implanted medical device

An absorbable implantable medical device made of iron-based alloy, including a base made of iron-based alloy and a complex, wherein the complex includes a complexing agent. In a physiological solution, the base made of iron-based alloy can react with the complexing agent to generate a water-soluble iron complex having solubility in the physiological solution of no less than 10 mg/l.

Peptide having titanium-binding ability

The present invention relates to a peptide having the ability to bind specifically to the surface of titanium. The titanium-binding peptide according to the present invention is fixed securely to the titanium surface so that the activity of a physiologically active substance linked to the peptide can be stably maintained over a long period of time.

Rapid acoustic tissue processing methods, systems, and devices

Provided are systems and methods for treating or processing tissue, and tissue products made using such systems and methods. Also provided are ball mill processing devices and systems useful for processing materials such as tissue.

Compositions derived from placenta and methods of producing the same

Compositions comprising unseparated amnion/chorion derived from the placenta and methods of preparing and using those compositions are provided. Washing or preservation of placental tissue according to the methods of the disclosure may allow for one or more benefits such as more efficient removal of blood remnants, retention of wound healing and tissue regeneration components, better handling characteristics, increased absorption potential, or improved healing capacity.

Method for manufacturing bone-regeneration material comprising biodegradable fibers by using electrospinning method

A bone-regeneration material that contains calcium phosphate particles in biodegradable fibers of plga manufactured by electrospinning. A plga resin is heated in a kneader until the resin viscosity becomes 102 to 107 pa·s.

Biocompatible implants for nerve re-generation and methods of use thereof

A biocompatible nerve conduit for nerve re-generation, wherein a porous fiber tube is coated with a bioresorbable hydrogel, with the fibers being formed from a polymer that supports nerve regeneration by preferential adsorption of endogenous proteins and braided with pores in the range from 5 to 200 micrometers using a kink-resistant braiding pattern and the hydro gel coating material and thickness being selected to control the overall porosity, so that nutrients and oxygen can diffuse through said hydrogel coating but the infiltration of fibrous tissue through the coating is prevented.. .

Method of sterilizing beverage dispenser and beverage dispenser

A beverage dispenser (1) includes a cold water tank (20) for storing cold water (50), a carbonation tank (30) disposed with at least a bottom portion thereof being submerged in the cold water (50) in the cold water thank (20), the carbonation tank being configured to generate carbonated water (60) by adding carbon dioxide gas to the cold water (50) supplied from the cold water tank (20), a carbonated water outlet passage (35) for taking out the carbonated water (60) from the carbonation tank (30) and a heater (41) for heating the cold water (50) in the cold water tank (20). In order to sterilize the above beverage dispenser (1), the heater (41) is caused to heat the cold water (50) in the cold water tank (20) to a temperature higher than a predetermined temperature, thereby to sterilize the cold water tank (20) and the carbonation tank (30).

Gas-generating polymer micells and manufacturing the same

The present invention relates to a gas-generating micelle prepared by coupling a polyethylene glycol derivative and an alkyl chloroformate. The gas-generating micelles according to the present invention are circulated in the body and deposited on the disease site to generate carbon dioxide, and thus a more enhanced ultrasonic diagnostic image can be obtained..

Portable bioluminescence in vivo monitoring of molecular and metabolic events in animals

A system for monitoring biological processes in vivo is provided. The system comprises an implantable luciferase biosensor comprising luciferase in a biocompatible matrix and a caged luciferin probe.

Methods and compositions for modulating gene expression

The present technology relates to compositions and methods for modulating expression of genes which include a target oligonucleotide sequence, such as repeats of a particular oligonucleotide sequence containing 3 to 10 nucleotides. In particular aspects, the present technology relates to agents having a formula a-l-b, wherein -l- is a linker; a- is a brd4 binding moiety; and —b is a nucleic acid binding moiety, such as a polyamide or complementary oligonucleotide, that specifically binds to the target oligonucleotide sequence..

Patch preparation containing an acid scavenger

An object of the present invention is to provide a patch preparation having an excellent skin permeability of medicament using an acid additional salt of basic medicament. Provided is a patch preparation comprising a support and an adhesive layer on one surface of the support, wherein the adhesive layer contains a basic medicament, a fatty acid-based ionic liquid, and potassium salts and/or potassium ions.

Activatable two-component photosensitizers

Provided herein is a two-component photosensitizer, which demonstrated robust and selective killing effects for transfected hek cells and affibody targeted a431 cancer cells when exposed to near infrared light excitation. Free mg2i is a pure and stable fluorogen; it is easy to synthesize and modify, and has no toxicity to cells.

Treatment of blood

Activation of senescent stem cells in humans to promote wound healing and other therapies, and to promote general enhancement of health by application of non-thermal atmospheric pressure plasma (ntapp) to tissues and body fluids such as blood. In particular, the targets of the ntapp are stem cells.

Humanized anti-cd40 antibodies and uses thereof

The present disclosure relates to anti-cd40 antibodies, such as humanized anti-cd40 antibodies, that may be used in various therapeutic, prophylactic and diagnostic methods. The antibodies generally block the ability of cd40 to bind cd154 and do so without activating the cell expressing cd40 (e.g., a b cell).

Gene optimized hantaan virus m segment dna vaccine for hemorrhagic fever with renal syndrome

A synthetic, codon-optimized hantaan virus (htnv) full-length m gene open reading frame that consists of a unique nucleotide sequence encoding htnv proteins. This synthetic gene was cloned into a plasmid to form the first optimized htnv full-length m gene that elicits neutralizing antibodies in animals when delivered in combination with a similarly optimized puumala virus (puuv) dna vaccine.

Methods and compositions using highly conserved pneumococcal surface proteins

Cold spot genes of s. Pneumoniae are disclosed that encode surface proteins that are universally conserved among known strains and have exceptionally low incidence of allelic variation.

Cholera toxin chimera and its use as a staph vaccine

The present invention relates to chimeric protein vaccines and methods of use thereof in the treatment of staphylococcus aureus. One embodiment of the present invention provides a method of generating an immune response in a mammal, that includes administering to the mammal, a composition having a chimeric protein having at least one of: a portion of a cholera toxin, a portion of a heat-labile toxin, and a portion of a shiga toxin; and an antigen having at least one of: an antigenic material from s.

Engineered listeria and methods of use thereof

The invention provides a bacterium containing a polynucleotide comprising a nucleic acid encoding a heterologous antigen, as well as fusion protein partners. Also provided are vectors for mediating site-specific recombination and vectors comprising removable antibiotic resistance genes..

Stabilized external preparation comprising thymosin beta 4 as an active ingredient

The present invention relates to a stabilized external preparation comprising thymosin beta 4 (tβ4) as an active ingredient. More specifically, the present invention relates to a therapeutically effective external preparation with improved stability and biological activity of tβ4.

Activators of cxcr3 for the treatment of angiopathies of the eye

The present disclosure describes methods of treating angiogenic disorders of the eye, such as macular degeneration, restenosis following glaucoma treatment or diabetic retinopathy, by administering an activator of c-x-c chemokine receptor 3 (cxcr3). In some embodiments, the activator of cxcr3 is interferon-γ-inducible 10 kda protein (ip-10) or a fragment or variant thereof, such as a fragment comprising or consisting of the c-terminal α-helix of ip-10.

Fibroblast growth factor-9 promotes hair follicle regeneration after wounding

The present invention provides methods for treating hair loss, treating, inhibiting, or suppressing a degenerative skin disorder, treating androgenetic alopecia (aga), generating new hair follicles (hf), and increasing the size of existing hf. The methods comprise epidermal disruption or administration of wnt, and administration of a fibroblast growth factor-9 polypeptide or another compound that upregulates sonic hedgehog gene signaling..

Methods of treating cancer

Methods of treating cancers comprising fgfr1 gene amplification, fgfr1 overexpression, fgfr3 overexpression, fgfr3 amplification, fgf2 overexpression, and/or fgf2 gene amplification are provided. In some embodiments, the methods comprise administering a fibroblast growth factor receptor 1 (fgfr1) extracellular domain (ecd) and/or an fgfr1 ecd fusion molecule.

Methods and compositions for production of recombinant pharmaceutical proteins in medicinal plants

Methods of tissue culture and in vitro propagation of medicinal plants, in particular, plants of the genera hydrastis, echinacea, kalanhoe, thymus and calendula are described. Methods of genetically engineering the medicinal plants are also described, along with methods of producing recombinant proteins in such plants.

Use of bacterial methionine metabolism for lifespan extension

The disclosure generally relates to microorganisms, methods, and compositions for reducing methionine content of a diet of a subject or extending a lifespan of the subject and processes for preparing the microorganisms and compositions.. .

Placenta-derived cells excreting c3 or c1r complement and composition containing same

The present invention relates to placenta-derived cells excreting c3 or c1r complement proteins, a pharmaceutical composition containing same, and a method for treating diseases using the placenta-derived cells. The placenta-derived cells, according to the present invention, can be effectively applied to alzheimer's disease, parkinson's disease, hiv, neurodegenerative diseases such as dementia and epilepsy, or angiogenesis-related diseases such as cancer and retinopathy, thereby having high industrial utility..

Agent for treating urinary incontinence including stem cells derived from amniotic fluid

The present invention relates to a cell therapy product which is intended for regenerating a sphincter muscle and which contains stem cells derived from amniotic fluid, and more particularly, to a cell therapy product which is intended for regenerating the sphincter vesicae and which contains stem cells derived from amniotic fluid. Also, the cell therapy product of the present invention can be provided in the form of a formulation for administration through injection, said formulation being injected into a hydrogel complex to thereby improve the effects thereof.

Nanoparticle based tumor endothelial targeting vaccine

Disclosed are methods, compositions of matter, and therapeutic protocols for treatment of cancer by selectively inducing immune responses against blood vessels feeding neoplastic tissue. In one embodiment, placental endothelial cells are stimulated with phorbol myristate acetate (pma) to induce release of nanoparticles that possess ability to: a) be taken up by antigen presenting; b) presented through direct and indirect presentation to cd4 and cd8 t cells, respectively; and c) utilized to stimulate cytoxic t cellular and humoral responses to selectively inhibit angiogenesis of tumors..

Muscle derived cells for the treatment of gastro-esophageal pathologies and methods of making and using the same

The present invention provides muscle-derived progenitor cells that show long-term survival following transplantation into body tissues and which can augment soft tissue following introduction (e.g. Via injection, transplantation, or implantation) into a site of soft tissue.

Method for mass producing proteins in mesenchymal stem cells

The present invention relates to the method for mass production of mesenchymal stem cell-derived proteins including various growth factors and cytokines, a mesenchymal stem cell conditioned medium containing a large amount of protein and produced by the above production method, cosmetic composition and pharmaceutical composition including the above conditioned medium for skin regeneration, anti-wrinkle, alopecia treatment, prevention of hair loss and promotion of hair growth. The method for mass production of the mesenchymal stem cell-derived protein of the present invention can greatly increase the amount of various growth factors and proteins which are known to be not expressed from mesenchymal stem cells or expressed only in very small amounts by the existing culture method, and the mesenchymal stem cell conditioned medium prepared by the above method contains a large amount of various kinds of cytokines and growth factors so that it has the excellent effect on skin regeneration, wrinkle improvement, prevention of hair loss, alopecia treatment and hair growth promotion..

Methods and compositions for infusion of transiently engrafting, selected populations of allogeneic lymphocytes to treat cancer

The invention provides methods and compositions for administration of allogeneic lymphocytes as an exogenous source of cd4+ t cell help for endogenous, tumor-reactive cd8+ t cells. Depletion of cd8+ t cells from the donor lymphocyte infusion reduces the risk of sustained engraftment and graft-versus-host disease.

T cell delivery of mda-7/il-24 to improve therapeutic eradication of cancer and generate protective antitumor immunity

Provided herein are methods and compositions useful for treating cancer, such as prostate cancer, through adoptive cell transfer of t cells derived from patients and genetically engineered to express mda-7/il-24 and/or other immune modulating agents. The methods described herein result in cancer cell death and reprogramming of the tumor immune compartment to restore antitumor immunity both at a primary tumor site and systemically..

Uridine diphosphate derivatives, prodrugs, compositions and uses thereof

This disclosure relates to the use of uridine diphosphate (udp) derivatives, salts and/or prodrugs thereof for the treatment of inflammatory conditions (e.g., psoriasis) and glaucoma, to prodrugs of udp derivatives, compositions comprising therapeutically effective amounts of those prodrugs of the udp derivatives and methods of using those prodrugs for treating various disorders including, e.g., neuronal disorders, including neurodegenerative disorders (e.g., alzheimer's disease, parkinson's disease) and traumatic cns injury, pain, down syndrome (ds), glaucoma, and inflammatory conditions, e.g., psoriasis and rheumatoid arthritis.. .

Methods of treating cancer patients with farnesyltransferase inhibitors

The present invention relates to the field of molecular biology and cancer biology. Specifically, the present invention relates to methods of treating a subject with a farnesyltransferase inhibitor (fti) that include determining whether the subject is likely to be responsive to the fti treatment based on genotyping and expression profiling of certain immunological genes and ras mutation status in the subject..

Maternal vitamin b6 administration for the prevention of increased adiposity, overweight or obesity in the offspring

The present invention generally relates to the early prevention of overweight, obesity, excessive fat accumulation and/or associated metabolic disorders in infants or children. For example, the present invention relates to the prevention of overweight, obesity, excessive fat accumulation and/or associated metabolic disorders in infants or children through appropriate nutrition for women desiring to get pregnant and/or during pregnancy and/or lactation.

Use of anthelmintic agents against dirofilaria immitis

This invention is directed to compounds and salts that are generally useful as agents to treat an infection with dirofilaria immitis. This invention also is directed to treatments comprising the administration of the compounds and salts to animals in need of the treatments..

Pharmaceutical composition comprising indole derivatives, process for preparation and use thereof

The invention provides well-defined and stable pharmaceutical compositions comprising indole derivatives of general formula 1, a process for the preparation of di-hydrochloride salts comprising a high content of the pharmacologically active isomer suitable for industrial production, and use of these in pharmaceutical compositions. The invention further provides a method for use of said compounds for the treatment of cancer.

Neuroregeneration supplement

A composition for enhancing neuroregeneration of the sciatic nerve in a mammal is provided that includes medicinally effective amounts of glycine, glutamine, and phenylalanine. In some embodiments, the glutamine can be l-glutamine and the phenylalanine can be d, l-phenylalanine.

Use of 1,3-diphenylprop-2-en-1-one derivatives for treating liver disorders

The invention provides 1,3-diphenylprop-2-en-1-one derivatives and pharmaceutical compositions comprising the same for treating liver disorders, in particular those requiring the reduction of plasma level of biochemical markers such as aminotransferases. The 1,3-diphenylprop-2-en-1-one derivatives of general formula (i) have hepatoprotective properties and can be used in methods for treating liver disorders involving the pathological disruption, inflammation, degeneration, and/or proliferation of liver cells, such as liver fibrosis or fatty liver disease..

Self-foaming cleansing composition containing clobetasol propionate, and use thereof in the treatment of psoriasis

A self-foaming composition for a topical application is described. The composition can include a medium which is cosmetically- or pharmaceutically-compatible with a topical application, and clobetasol propionate.

No-rinse chemical foam containing trifarotene, and use thereof in the treatment of ichthyosis

A self-foaming composition is described that includes trifarotene, for a no-rinse topical application. The composition can include: at least one intermediate composition b including a gas-generating agent; at least one intermediate composition a including an agent for activating the gas-generating agent; and trifarotene or one of the pharmaceutically acceptable salts thereof being present in at least one of the intermediate compositions a and b.

No-rinse chemical foam containing trifarotene, and use thereof in the treatment of acne

A self-foaming composition is described that includes trifarotene, for a no-rinse topical application and for application to the skin. The composition can include: at least one intermediate composition b including a gas-generating agent; at least one intermediate composition a including an agent for activating the gas-generating agent; and trifarotene or one of the pharmaceutically acceptable salts thereof being present in at least one of the intermediate compositions a and b.

Force-sensing percutaneous gastrostomy tube device and methods thereof

A percutaneous endoscopic gastronomy tube device includes an elongate tube extending between a first end and a second end. A flange is coupled to the elongate tube at the second end.

Smart container insert

Disclosed is a messaging system that can be used with either a locked or unlocked container to indicate an elapsed time, such as an elapsed time for taking medication, unauthorized movement, or opening of the container. A capsule placed in the container communicates to an application that may generate alerts for vial openings, failure to open vial when medication due, pilfering or unauthorized movement.

Medication compliance alert device

Example embodiments relate to medication compliance alert devices. An example embodiment includes a method.

Fluid containers and detecting a fluid level therein

Fluid containers having a volume marking(s) and conductive element(s) disposed at the volume marking(s) and a common conductive element are provided. For example, the fluid container has a wall forming the volume.

Female sexual stimulation device

A sexual stimulation device includes a main body having a generally blunt first end, a top surface, a bottom surface, and a dildo that extends outward from the bottom surface of the main body. The dildo including a curved shaft that forms an obtuse angle.

Cooling garments, warming garments, and related methods

The present disclosure generally relates to intelligent garments that provide thermal regulation in a variety of environments. The garments may include different layers such as a hydrophobic layer in direct contact with a wearer's skin surface and saturated with an aqueous mixture, a spacer layer, a reflective layer, and an outer hydrophobic layer.

Orthopedic post pad

An orthopedic post pad comprising: an inner cushion layer, the inner cushion layer having a lune shape with a first peak, and a second peak; a post hole located in the inner cushion layer on a side opposite the two peaks; an outer cushion layer enveloping the inner lateral surface and concave surface of the inner cushion, the outer cushion layer and inner cushion layer together generally forming a right cylindrical shape.. .

A controlled release iodine structure for use with wound care

Systems, methods, and apparatuses for generating and releasing iodine are described. Some embodiments may include a dressing member including a plurality of iodine-forming reagents and a water-swellable material.

Preparation jig for tympanic membrane regenerating agent and preparation vessel for tympanic membrane regenerating agent

[solution] a preparation jig for a tympanic membrane regenerating agent (1a) and a preparation vessel for a tympanic membrane regenerating agent (1a) each include: a vessel (3a) including housing walls (6, 7) forming an interior space (s1) housing a medicinal solution support (2), and including an opening (6h) opening in one direction and formed in the housing walls (6, 7); and a holding portion (4a) disposed in the interior space (s1). The deep side of the interior space (s1) is a housing portion (s3) housing the medicinal solution support (2) holding a medicinal solution.

System for neuroprotective therapy for glaucoma

Providing neuroprotective therapy for glaucoma includes generating a micropulsed laser light beam having parameters and characteristics, including pulse length, power, and duty cycle, selected to create a therapeutic effect with no visible laser lesions or tissue damage to the retina. The laser light beam is applied to retinal and/or foveal tissue of an eye having glaucoma or a risk of glaucoma to create a therapeutic effect to the retinal and/or foveal tissue exposed to the laser light beam without destroying or permanently damaging the retinal and/or foveal tissue and improve function or condition of an optic nerve and/or retinal ganglion cells of the eye..

Point of service manufacture of custom headwear

A method for fabricating an article of headwear for a subject is provided. The method comprises: generating a three-dimensional digital data file for the subject at a clinic by capturing a three-dimensional data file representative of the head by utilizing apparatus located at the clinic operating to capture three-dimensional data representative of the head; utilizing a processor to process the three-dimensional digital data file to produce a device file comprising the shape for the article of headwear; and manufacturing the article of headwear at the clinic by utilizing an additive manufacture device located at the clinic to operate with the three-dimensional digital data file..

Assistance system for cognitively impaired persons

A device for providing assistance to a person comprises a data input for obtaining person related data representing data obtained by monitoring the person, a data processing unit for processing the obtained person related data to determine the person's mental state and/or cognitive level from the obtained person related data, to detect if the person has limited or no ability to perform a desired task and to generate assistance data in case of detection that the person has limited or no ability to perform the desired task and/or if the person's current mental state and/or cognitive level is below a threshold or out of a distribution or value range required to perform the desired task, said assistance data representing data directed to supporting the person in performing the desired task by adapting the number of functions of an appliance accessible and controllable by the person according to the person's current mental state and/or cognitive level, and a data output for providing said assistance data for supporting the person in performing the desired task.. .

Stents with dual tissue-wall anchoring features

The present disclosure relates generally to the field of stents for body lumen drainage. In particular, the present disclosure relates to systems and methods for forming a fluid channel between tissue walls of varying thickness using a stent..

Arthroplasty components

Systems, kits and methods for long bone arthroplasty that include arrays of humeral head prosthesis components, each having on a first side a bone articulation surface that has an overall generally hemielliptical convex shape defined by a major axis and a minor axis, the bone articulation surface having an apex and a base that each has an non-circular elliptical cross sectional shape, the prosthesis components having on an opposite side, adjacent the base, a bone contact surface. The humeral head prosthesis components in the arrays vary from having a base with a more circular cross sectional shape to a more elongated elliptical cross sectional shape with increasing size..

Customized acetabular cup positioning guide and generating and employing such a guide

Implementations described and claimed herein provide an arthroplasty system and methods for positioning an acetabular cup implant. In one implementation, the system includes a shape-match hip guide having a patient specific mating region that is a negative of the surface contour of the inside surface of the patient's acetabular cup, and a directional rod that extends generally along the axis of the patient's femoral head and femoral neck.

Methods of designing three-dimensional lattice structures for implants

The methods disclosed herein of generating three-dimensional lattice structures and reducing stress shielding have applications including use in medical implants. One method of generating a three-dimensional lattice structure can be used to generate a structure lattice and/or a lattice scaffold to support bone or tissue growth.

Medical ultrasonic treatment device

A medical, particularly a dental or dental surgical, ultrasonic treatment device for generating ultrasonic vibrations and transmitting the ultrasonic vibration to a tool, which can be connected to the ultrasonic treatment device, the medical ultrasonic treatment device having: an ultrasonic vibration generator with a plurality of piezoelectric elements to which an electric voltage can be applied, and a circuit board to supply the plurality of piezoelectric elements with the electric voltage. Furthermore, a method for manufacturing a corresponding medical ultrasonic treatment device is described..

Methods of using an angled endoscopic for visualizing a body cavity with robotic surgical systems

A method of visualizing a body cavity during a surgical procedure including positioning an elongated body of an angled endoscope in a first position within a body cavity of a patient, rotating the elongated body about a longitudinal axis in response to a command point, capturing a plurality of images with an image capture device positioned within the elongated body as the elongated body is rotated, and generating a panoramic view of the body cavity from the plurality of images. In the first position of the elongated body, a surgical site is within a field of view of the image capture device.

Controlling roll for a device in a computer-assisted medical system

Roll control is provided for a device by controlling the roll-angle offset about the device roll axis in correspondence to a specified rotation of a reference frame for the device. This specified rotation may correspond to a roll-free rotation of the reference frame to align a corresponding reference roll axis with the device roll axis.

Insertion device positioning guidance system and method

A system and a method for an insertion device positioning guidance system comprising: an electromagnetic field generator configured to generate an electromagnetic field covering a treatment area; a plate sensor configured to be positioned within the treatment area in a location defining an orientation of a subject; a reference sensor configured to be positioned, within the treatment area, on the subject's torso, the reference sensor is configured to define a reference coordinate system representing the position and orientation of the subject's torso relative to said field generator; a registration sensor configured to mark at least a first and a second anatomic locations relative to the reference coordinate system; and a processor configured to operate said field generator, read signals obtained from said the plate sensor, said reference sensor and said registration sensor, calculate a position and orientation thereof relative to said field generator, generate a 3d anatomic map representing the torso of the subject and the first and second anatomic locations, said processor is further configured to facilitate visualization on the 3d anatomic map of a position, orientation and/or path of a tip sensor, located in a distal tip section of the insertion device, with respect to the first and second anatomic locations, independent of the subject's movement and independent of deviations in the position and/or orientation of said field generator, thus determination of a successful medical procedure is facilitated.. .

Surgical navigation system, surgical navigation method and program

A system stores clustering information obtained by clustering multiple sets of viewpoints relative to teeth of a three-dimensional model of a patient and projection images of a head including the teeth from the respective viewpoints. At the time of a surgery, the system creates comparative images from a photographed image taken by a monocular camera and searches for any viewpoint having a projection image similar to the comparative image sequentially from a first hierarchy to a final hierarchy in the clustering information.

Reduction methods for aligning bone segments using customized jigs

Methods for aligning bone segments using custom jigs are disclosed. In one technique, bone segments are aligned using interaction elements, imaging, virtual fracture alignment, and a custom jig.

Devices coronary intervention assessment, planning, and treatment based on desired outcome

The present disclosure relates generally to the assessment and treatment of vessels, including for percutaneous coronary intervention (pci) and coronary artery bypass grafting (cabg). For example, some embodiments of the present disclosure are suited for identifying the available intervention technique(s) suitable to achieve a desired outcome selected or input by a user.

Handpiece for laser device

An electro-mechanical-type handpiece is specially designed to be used with a laser generator, particularly those that use a co2 laser and provide a laser beam in fractional mode. The fractional mode laser beam is provided in a pattern of homogeneous points aligned in rows, columns or diagonally, and such a pattern allows internal tissue along an entire length of a vagina of a patient to be treated and a pelvic floor of the patient to be retracted, such that a urinary bladder of the patient is elevated and, owing to the change in angle thereof, slight or moderate losses of urine are resolved or improved.

Laser device and driving laser device

A laser device according to the present invention may comprise: a pumping laser supply unit for emitting a pumping laser having a nano-second pulse width; and a laser output unit disposed at one side of the pumping laser supply unit and generating an output laser which is pumped by the pumping laser to have a nano-second pulse width corresponding to the pulse width of the pumping laser.. .

Methods and devices for controlling motorized surgical devices

Methods and devices for controlling motorized surgical devices are provided. In general, the methods and devices can allow a surgical device to grasp and cut tissue.

Area ratios of patterned coatings on rf electrodes to reduce sticking

An electrosurgical system includes an rf current generator, a handle body, and an end effector. The end effector may include a first and a second energy delivery surface.

Generator for supplying a coagulation instrument and control same

The device and method according to the invention allow a particularly fast, gentle, and secure fusion of vessels between two coagulation electrodes. Resistance oscillations are generated in the biological tissue, said oscillations alternatingly moving above and below a tissue resistance value of, e.g., 50 ohm.

Electromagnetic tissue ablation device

Electromagnetic (em) tissue ablation device comprising an em field generator unit, at least two coaxial elongated elements (i.e. An external one and an internal one) and a mechanism for varying the em field, wherein said internal element is a part of said generator and said mechanism being adapted to vary the em field for a specific tissue area..

Ultrasound probe with integrated needle advancer

The present disclosure is directed to an ultrasound imaging system with an integrated needle advancer. More specifically, the ultrasound imaging system includes an ultrasound probe having a transducer housing, a transducer transmitter, a needle assembly, and a controller.

Robotically-controlled shaft based rotary drive systems for surgical instruments

A surgical instrument including an end effector that has a selectively reciprocatable implement movably supported therein. The implement is selectively advanceable in a distal direction upon application of a rotary actuation motion thereto and retractable in a proximal direction upon application of a rotary retraction motion thereto.

Robotically-controlled shaft based rotary drive systems for surgical instruments

A surgical instrument including an end effector that has a selectively reciprocatable implement movably supported therein. The implement is selectively advanceable in a distal direction upon application of a rotary actuation motion thereto and retractable in a proximal direction upon application of a rotary retraction motion thereto.

Robotically-controlled shaft based rotary drive systems for surgical instruments

A surgical instrument including an end effector that has a selectively reciprocatable implement movably supported therein. The implement is selectively advanceable in a distal direction upon application of a rotary actuation motion thereto and retractable in a proximal direction upon application of a rotary retraction motion thereto.

Biopsy device

Aspects of the present invention are generally directed to a biopsy device configured to engage target tissue within a patient and to remove a sample of the target tissue from the patient. The biopsy device comprises an elongate catheter configured to be inserted into a patient.

Medical image diagnosis apparatus

A medical image diagnosis apparatus includes a power factor corrector, a dc/dc converter, and a battery device. The power factor corrector is supplied with ac power and generates dc power to drive individual parts of the apparatus.

Ultrasound diagnosis device, operation ultrasound diagnosis device, and computer-readable recording medium

An ultrasound diagnosis device includes a controller. The controller is configured to: calculate a feature related to an ultrasound signal, based on the ultrasound signal received from an observation target; estimate a physical quantity of scattering bodies included in the observation target, by using: a relation derived based on a known physical quantity of an object and a feature obtained from the object, the object including scattering bodies having the known physical quantity; and the calculated feature of the observation target; and generate information to be displayed on a display, the information including a result of the estimation..

Ultrasound imaging system having automatic image presentation

An apparatus and method of generating a 3d ultrasound image includes acquiring a 3d volumetric data set corresponding to a 3d imaging volume of an ultrasound probe in a 3d detection volume; acquiring a position of the ultrasound probe with respect to the 3d detection volume; acquiring a position of an interventional medical device with respect to the 3d detection volume; determining a position of the interventional medical device relative to the 3d imaging volume of the ultrasound probe; determining an interventional medical device-aligned plane that intersects with a longitudinal axis of the interventional medical device; extracting a texture slice from the 3d imaging volume for a corresponding interventional medical device-aligned plane positional and rotational orientation; mapping the texture slice onto the interventional medical device-aligned plane; and rendering the interventional medical device-aligned plane as a 3d ultrasound image and displaying the rendered 3d ultrasound image on a display screen.. .

Portable ultrasound device

Systems and methods for stroke detection in accordance with embodiments of the invention are illustrated. One embodiment includes a system for detecting strokes, including a processor, a first ultrasound transmitter located on a patient's head in communication with the processor, a first ultrasound receiver located on the patient's head in communication with the processor, a memory in communication with the processor, including a stroke diagnostics application, where the stroke diagnostics application directs the processor to transmit a first ultrasound signal from the first ultrasound transmitter across a patient's brain, the brain comprising a first and second hemisphere, receive the first ultrasound signal using the first ultrasound receiver, where the ultrasound signal is affected during transit by harmonics generated by microbubbles in the blood of the patient stimulated by the first ultrasound signal, and detect that a stroke has occurred based on the harmonic effects on the first received ultrasound signal..

Medical imaging systems using robotic actuators and related methods

Methods may be provided to operate an imaging system using a contact imaging probe to generate imaging of a body. A robotic actuator may be controlled to position the contact imaging probe at a first location on a surface of the body such that the contact imaging probe is in a first radial alignment with an imaging isocenter.

Image processing apparatus, x-ray diagnostic apparatus, and image processing method

An image processing apparatus according to an embodiment includes processing circuitry. The processing circuitry extracts a fixed object included in chronologically collected x-ray images and having a substantially fixed position.

Medical image processing apparatus, medical image processing method, and x-ray diagnostic apparatus

A medical image processing apparatus comprises processing circuitry configured to select a reference image from blood vessel images based on contrast images acquired in time series and conduct a transformation process on other blood vessel images such that blood vessel shapes in the other blood vessel images match a blood vessel shape in the reference image, generate a color image where a color that corresponds to a temporal change in a pixel value is assigned to each pixel based on the blood vessel images after the transformation process, and display the color image on a display.. .

X-ray imaging system

An x-ray imaging system includes an x-ray talbot imaging device and an image processing device. The image processing device includes a hardware processor and a display.

Intraoral sensor positioning system

A sensor positioner for use with a dental digital radiography system includes an x-ray source which transmits through an x-ray cone an x-ray stream which has a generally circular cross-section and an intraoral sensor which is aligned with the x-ray source. The sensor positioner includes an aiming ring and a sensor carrier.

X-ray diagnostic apparatus, image processing apparatus, and image processing method

An x-ray-diagnostic apparatus generates time-series first vessel images corresponding to a first direction, and generates second vessel image corresponding to a second direction. The apparatus generates third vessel images corresponding to the second direction, by transforming more than one piece out of the first vessel images based on a blood vessel shape in one of the first vessel images and a blood vessel shape in at least one of the second vessel image, the third vessel image corresponding to respective time phases of the first vessel images.

Simultaneous estimation of respiratory mechanics and patient effort via parametric optimization

Respiratory variables are estimated on a per-breath basis from airway pressure and flow data acquired by airway pressure and flow sensors (20, 22). A breath detector (28) detects a breath interval.

Methods and determining biological effects of environmental sounds

Methods and apparatus for determining biological effects of environmental sounds are disclosed. An example apparatus includes a sound characteristic analyzer to identify a sound event based on audio data in an environment.

Pulse measurement device, pulse measurement method and non-transitory computer readable medium

It is possible to measure a pulse rate correctly, when a body moves. A frequency analysis unit 13 generates a pulse wave frequency signal by converting pulse wave detection signals detected by a light sensor 20 into a frequency domain signal from time domain signals.

Method to project a two dimensional image/photo onto a 3d reconstruction, such as an epicardial view of heart

A three-dimensional (3d) electrical mapping system and method may be used to generate a 3d image of the epicardial surface of a heart by integrating one or more epicardial images with a 3d image of the cardiac structure that may be generated by real-time 3d location and mapping system for cardiac mapping and ablation. The visual textural representation of the epicardial surface of the heart may be reconstructed using, for example, an image sensor or camera-based catheter to collect images of the epicardial surface.

Movement compensation for sensor-equipped athletic garments

An athletic garment includes connective segments that compensate for motion of an athlete wearing the athletic garment. Right and left connective segments couple right and left arm segments of the garment to a torso segment, respectively.

Evaluation of an implanted prosthesis

Evaluating an implanted hearing prosthesis, including operating the implanted hearing prosthesis, capturing sound generated by a transducer of the prosthesis during said operation, and comparing the captured sound to a sound model.. .

System and the analysis and transmission of data, images and video relating to mammalian skin damage conditions

Data, images and video characterizing mammalian skin damage conditions are collected and analyzed in part using a mobile device as a data collection engine at the point of care. The device establishes communications with a server where the information is stored in a database.

Method and system for locating seizure focus from interictal data

Methods and systems for identifying epileptogenic regions of the brain and locating seizure foci can use only interictal eeg data. These methods and systems enable a physician to locate seizure foci without having to wait for a patient to experience a seizure and have it recorded.

Enclosed desorption electrospray ionization probes and use thereof

The invention generally relates to enclosed desorption electrospray ionization probes, systems, and methods. In certain embodiments, the invention provides a source of desi-active spray, in which a distal portion of the source is enclosed within a transfer member such that the desi-active spray is produced within the transfer member..

Automatically classifying animal behavior

Systems and methods are disclosed to objectively identify sub-second behavioral modules in the three-dimensional (3d) video data that represents the motion of a subject. Defining behavioral modules based upon structure in the 3d video data itself—rather than using a priori definitions for what should constitute a measurable unit of action—identifies a previously-unexplored sub-second regularity that defines a timescale upon which behavior is organized, yields important information about the components and structure of behavior, offers insight into the nature of behavioral change in the subject, and enables objective discovery of subtle alterations in patterned action.

Device for tracking, monitoring and analyzing biophysical-activities of users

The present disclosure envisages a device for tracking, monitoring and analyzing biophysical-activities of a user. The device includes a motion and activity sensing unit to sense and track motion, direction and acceleration of the biophysical-activities and generate a plurality of motion and activity related signals, a biosensor unit to sense and track a plurality of health parameters and generate a plurality of health related signals, a bio-mechanical tracking unit to sense a plurality of activity parameters including speed, count, axis, direction and position, and generate a plurality of bio-mechanical related signals, a signal conditioning unit to generate conditioned health data and conditioned bio-mechanical data based on the plurality of motion and activity related signals..

Method, device and system for sensing neuromuscular, physiological, biomechanical, and musculoskeletal activity

A neuromuscular, physiological, biomechanical, or musculoskeletal activity monitoring system for a subject is provided. The system includes a wearable inertial measurement unit including at least one accelerometer and/or at least one gyroscope.

Nebulizing devices and systems having biometric data acquisition and monitoring capabilities

Embodiments of the present disclosure relate generally to devices and systems for administering pharmaceutical, monitored and/or biological agents via nebulization to a subject. In certain embodiments, the present disclosure provides devices, methods and systems for biometric and diagnostic data acquisition and patient monitoring before, during, and after the nebulization and administration of pharmaceutical, monitored and/or biological agents to a subject.

Systems, devices and methods for enhancing operative accuracy using inertial measurement units

Accuracy enhancing systems, devices and methods are provided using data obtained from inertial measurement units (imus). Imus are provided on one or more of a patient, surgical table, surgical instruments, imaging devices, navigation systems, and the like.

Generating orthotic product recommendations

A method to generate orthotic product recommendations for users includes receiving interactions from a user including identification of one or more extremity areas of the user's body, the one or more extremity areas relevant to selection of one or more orthotic products. On-screen cues and interactions are provided to assist in positioning of the one or more extremity areas relative to one or more imaging sensors.

Magnetic resonance imaging

Methods and devices for magnetic resonance imaging are provided. In one aspect, a method of magnetic resonance imaging includes: for each scanning step in a scanning sequence for a subject, determining a longitudinal magnetization intensity of a characteristic tissue of the subject according to a current running condition of the scanning sequence, obtaining an inversion time corresponding to a characteristic tissue suppressing pulse to be generated according to the determined longitudinal magnetization intensity, generating the characteristic tissue suppression pulse, generating an imaging pulse sequence when the inversion time elapses after generating the characteristic tissue suppression pulse, and receiving an echo signal from the subject, the echo signal corresponding to the generated imaging pulse sequence.

Method, system and image-guided insertion of implant devices

A method of imaging an implant device in a computing device is provided. The computing device includes a processor interconnected with a memory and a display.

Deep personalization based on contextual neurofeedback

A method and system for operating a neural feedback system is disclosed. The method includes recording brain waves of a user, recording sensor data measuring at least one of a physical state or an activity of the user, and generating recorded context-based brain wave information by detecting correlations between the recorded brain waves and the recorded sensor data.

System and cuffless blood pressure estimation

Disclosed is a system for estimating arterial blood pressure. The system includes a heartbeat detection module configured to receive an electrocardiogram signal, and detect one or more qrs complexes of the electrocardiogram signal.

System for analyzing electrophysiological data and analyzing electrophysiological data

The present invention concerns a system (100) for analyzing electrophysiological data, especially intracardial electrogram data, the system (100) comprising a data processing and control unit (15) for processing the electrophysiological data, a data output unit comprising a data output screen (324) for displaying results of electrophysiological data analysis, wherein the data processing and control unit (15) being configured to receive electrophysiological data obtained from a mapping catheter assembly (110, 111) that comprises an electrode assembly (120, 80) with a plurality of n electrodes (82), each electrode (82) configured for measuring electrophysiological data in the form of electrogram signals. The data processing and control unit (15) comprises an engine for performing an optical flow analysis of the electrophysiological data to generate series of vector data (40) representing the average speed and direction of movement of clusters of the electrophysiological data, the data output unit being configured to display the vector data on a data output screen (324) of the data output unit..

Passive arrhythmias detection based on photoplethysmogram (ppg) inter-beat intervals and morphology

A method for event detection in a user-wearable device includes receiving, from a first sensor implemented in the user-wearable device, photoplethysmogram (ppg) signals; processing, at a processor, the ppg signals to obtain ppg signal samples; detecting, at the processor, beats in the ppg signal samples; dividing the ppg signal samples into ppg signal segments; extracting at least one inter-beat interval (ibi) feature in each ppg signal segment; classifying, at the processor, each ppg signal segment using the extracted ibi feature associated with the ppg signal segment and using a machine learning model; in response to the classifying, generating, at the processor, an event prediction result for the ppg signal segment based on the extracted ibi feature; and displaying the event prediction result at the user-wearable device. In another embodiment, the method further includes extracting morphology based features..

Mri system, mri apparatus, and mri method

In one embodiment, an mri apparatus is configured to be connected with a pressure device that externally pressures a blood vessel of an object, and includes a scanner configured to perform imaging on the object and processing circuitry. The processing circuitry controls the pressure device in such a manner that ischemia and reperfusion are caused with respect to the object, determines a start timing of the imaging on the basis of a state of pressurization caused by the pressure device, causes the scanner to perform the imaging on the object in accordance with the start timing, and generates an image by using data acquired in the imaging..

Blood flow measurement apparatus

A blood flow measurement apparatus of an embodiment includes an image acquisition unit, an image region specification unit, a measurement location setting unit, a scanner, and a blood flow information generation unit. The image acquisition unit acquires an image of a living body.

Endoscope system and analyzing apparatus

An endoscope system includes: a light source apparatus; an endoscope having an imaging unit that includes an image sensor configured to generate color image data imaging biological tissue illuminated by light emitter by the light source apparatus; and a processor that has a first parameter generation unit configured to generate a first parameter that has sensitivity to a first feature amount of the biological tissue but does not have sensitivity to light scattering by the biological tissue based on the color image data, and a first feature amount acquisition unit configured to acquire the first feature amount based on the first parameter.. .

Protoporphyrin ix (ppix) imaging

A medical imaging system provides simultaneous rendering of visible light and fluorescent images. The system may employ dyes in a small-molecule form that remain in a subject's blood stream for several minutes, allowing real-time imaging of the subject's circulatory system superimposed upon a conventional, visible light image of the subject.

Capsule endoscope and capsule endoscope system

A capsule endoscope includes a sensor, an analyzer, a counter, a signal generator, and an imager. A count value becomes a reference value when an imaging synchronization signal is generated.

Endoscope apparatus

An endoscope apparatus includes an imager that outputs an imaging signal and an image processor that generates an emphasis image signal and a non-emphasis image signal based on the imaging signal. The emphasis image signal corresponds to emphasis narrow band light included in an emphasis wavelength range that includes at least one of a maximum wavelength that takes a maximum value of an optical absorption spectrum and a color-range largest wavelength that takes a largest value of the optical absorption spectrum.

Cookware handle cover

A panhandle cover made of a heat-resistant material including leather is generally of a longitudinally-split tubular configuration with its longitudinal split having the converging flanks overlapping one inside the other. The nature of genuine leather enables the flanks to conform to any pan-handle as it wraps around the handle.

Stirring body and heating/stirring cooker

A heating/stirring cooker includes a stirring body. The stirring body is detachably attached to the interior of a container, and stirs the food.

Warming device using electromagnetic induction method

The present invention relates to a warming device using an electromagnetic induction method, comprising, a main body, in the form of a support, which includes an electromagnetic induction coil for generating a magnetic field when applying an alternating current power to an upper surface thereof, and a container having a bottom surface which is formed to be seated on the upper surface of the main body, wherein the bottom surface comprises a metal body which is induction-heated by electromagnetic interaction with the generated magnetic field when the bottom surface is seated on the upper surface of the main body. The present invention provides a warming device using an electromagnetic induction method, which maintains a constant temperature of the container, thereby always enabling a user to drink coffee or tea at a desired temperature..

Espresso coffee extraction device

An espresso coffee extraction device includes an extraction piston driving unit having an extraction piston that, when coffee particles are supplied to a two-way cylinder via a coffee bean grinder to extract espresso coffee automatically, descends and injects hot water into the coffee with a strong pressure, thereby generating coffee liquid. A two-way cylinder driving unit moves leftward/rightward, continuously extracts coffee via a coffee extraction filter unit, and discharges coffee remnants to the outside after the extraction when the extraction piston ascends.

Bed

A bed assembly that includes a platform that would typically receive a mattress so that the platform can support a person in a lying position. The platform is supported by a post that extends downwardly from the platform to base.

Oscillation mechanism for chairs

An oscillation mechanism for chairs includes a support frame, a structure coupled to the support frame to rotate about a first axis, an elastic element interposed between the support frame and the structure and configured to oppose a reaction force to an oscillation of the structure. The reaction force generates a reaction moment acting on the structure with respect to the first axis.

Seat reclining device

A seat reclining device includes: a first gear member; a second gear member; paired wedge members arranged in an eccentric space; a biasing member which biases the paired wedge members in directions away from each other; and a drive member. The drive member includes a first drive protrusion which is arranged in a small-width portion of the eccentric space and a second drive protrusion which is arranged in a large-width portion of the eccentric space.

Height-adjustable workstation

An intelligent height-adjustable workstation includes a desktop and a seat cushion. The bottom of the desktop is supported by legs.

Harness and holder for gas detector

A body harness has a waist belt configured to form a closed loop around a user's waist and has a side portion corresponding to the user's side and a rear portion corresponding to the user's back. A shoulder strap is constructed to extend over the user's shoulder and has a front portion with a first strap end connected to the side portion of the waist belt and a back portion with a second strap end connected to the rear portion of the waist belt.

Carry-all bag with fixed insulated and non-insulated compartments

The present invention is directed to a soft-sided carry-all bag containing fixed insulated and non-insulated compartments for extensive storage of various items needed for everyday use including, among other things, food, footwear, laptop computers, cellular phones, books and notebooks, writing or eating utensils, water and drinks bottles, eyeglasses, coins, wallets, credit cards, cosmetics, toiletries, and clothing. The bag is meant to provide an individual with a means for consolidating such various items of everyday use without sacrificing aesthetic features, and generally includes a flexible main compartment for the storage of larger items, a rigid insulated compartment for the storage of perishable items, and a rigid non-insulated compartment for the storage of smaller items, each with separate access.

Footwear designing tool

Computer based systems and methods for designing (e.g., customization) of consumer products, articles of footwear, knit footwear uppers, and the like. In some embodiments, a user may generate and/or modify footwear designs using a footwear design interface.

Intermittent vectored digital manipulation device and method

Footwear that includes an interdigital boss that is positioned on the footwear and extends upward from a sole of the footwear in a configuration and direction that is more anatomically correct than an improperly positioned digit of a wearer of the footwear so as to provide intermittent corrective forces on the wearer's foot as the wearer walks that prevent bunions from forming on the wearer's foot. The boss provides a slight corrective motion during load bearing and a non-correcting position during the swing phase of the gait cycle of the wearer so as to stretch soft tissues in the wearer's foot, to provide pain relief, and to delay or prevent the onset of degenerative diseases, such as bunions.

High-energy power generation device for casual shoes

This disclosure discloses a high-energy power generation device for casual shoes, comprising a battery, a motor, a worm, a forward transmission crown gear, a transmission gear set, a backward transmission crown gear and a planetary gear set. This disclosure provides an efficient high-energy power generation device, which is concise in structure and exquisite in design.

Heater for an electrically heated aerosol generating system

An electrically heated aerosol generating system for receiving an aerosol-forming substrate includes at least one electric heater for heating the aerosol-forming substrate to form the aerosol. The heater includes a heating element of a first cross section electrically connected to a plurality of elongate support elements.

Aerosol-generating article and manufacturing such aerosol-generating article; aerosol-generating device and system

An aerosol-generating article (10) has a longitudinal extension and comprises aerosol-generating substrate (20, 21) extending along the longitudinal extension and susceptor material (30, 31) extending along the longitudinal extension. The aerosol-forming substrate (20, 21) and the susceptor material (30, 31) form an extrudate having a same cross-sectional shape along a length of the extrudate.

Aerosol provision system

The present disclosure relates to an aerosol provision cartridge for use with an aerosol provision system, the cartridge including a liquid storage region including a source liquid, the source liquid including nicotine and at least one acid; an aerosol generating region in fluid communication with the liquid storage region; and one or more metallic components, located substantially outside of the aerosol generating region and liquid storage region, wherein at least one of the metallic components has a coating comprising silver and/or gold.. .

Apparatus for generating an inhalable medium

Apparatus and methods for generating an inhalable medium are disclosed. An apparatus includes a container for holding a liquid, a heater for volatilizing liquid held in the container to generate a flow of at least one of a vapor and an aerosol in use, and a receptacle for receiving material.

Article for use with heating smokable material

Disclosed is an article for use with apparatus for heating smokable material to volatilize at least one component of the smokable material. The article includes a cavity for receiving smokable material, and a coil of heating material that is heatable by penetration with a varying magnetic field to heat the cavity.

Aerosol generating material and devices including the same

There is provided a solid aerosol generating material including about 5-35 wt % tobacco extract; about 50-80 wt % filler; about 10-35 wt % aerosol generating agent; and about 2.5-10 wt % binder; wherein weight percentage is calculated on a dry weight basis.. .

Honey compositions and methods of making the same

A process for producing an infused honey composition having a moisture content of 15% to 19% w/w is described. The process generally includes adding an infusing agent to honey to form an infused honey composition.

Systems and methods for controlling water quality in food processing

A chiller bath includes a tank for holding a volume of chiller water; a dosing system for dosing a first solution and a second solution into the chiller water, arranged to create a plurality of zones within the volume of water, wherein each zone has a higher concentration of either the first or the second solution than surrounding portions of the volume of water; and a meat or poultry immersion arrangement for immersing and moving carcasses in the chiller water. A method for reducing bacterial load on meat or poultry includes generating a plurality of zones within a chiller bath containing water by dosing a source of alkalinity and antimicrobial into the water, wherein the plurality of zones comprises at least one alkaline zone with a ph above 8.5, and at least one antimicrobial zone with ph below 8.5; and submersing meat or poultry in the bath.

Smoke generator

A smoker includes a smoke generator that is configured to provide a controllable method of producing smoke without creating a flame. The device includes a housing including a hopper for storing a smoking fuel within the interior of the housing.

Smoker with smoke management system

A smoker for cooking a food product that has a smoke dissipater mounted inside the cabinet for dissipating smoke using a high capacity ion generator for negatively charging smoke molecules so that the negatively charged molecules agglomerate with positively charged smoke molecules resulting in heavier molecules that precipitate out of the air within the cabinet. The smoker further may include charged plates within the cabinet that attract the charged smoke molecules to further accelerate dissipation of the smoke within the cabinet.

Method for preparing a canine model of atherosclerosis

The present invention relates to a method for preparing a canine model of atherosclerosis, in particular, relates to a method for preparing an apolipoprotein e (apoe) gene knock-out disease canine model with the use of gene knock-out technology.. .

Nucleic acid construct comprising a p16 promoter controlling expression of a transgene that causes apoptosis in senescent cells

This document relates to methods and materials involved in the removal of senescent cells within a mammal. For example, transgenic non-human animals that can be induced to delete senescent cells are provided..

Management apparatus, individual management system, and individual search system

[solving means] a management apparatus according to an embodiment of the present technology includes a control unit. The control unit extracts, on the basis of first information that is generated by a sensor device worn by an individual and is related to a living body of the individual, a specific individual satisfying a predetermined condition, and generates, on the basis of position information related to a position of the specific individual, search information for causing a mobile object to move to the position of the specific individual..

Livestock management system, sensor apparatus, and estimation a state of a livestock animal

[object] to provide a livestock management system, a sensor apparatus, and an estimation method for a state of a livestock animal with which states of livestock animals can be easily and accurately estimated. [solving means] a livestock management system according to an embodiment of the present technology includes a management apparatus.

Reduce pull leash apparatus and methods

In some embodiments, a reduced-pull leash device includes a first extendible leash section and a second leash section. The second leash section is longer than the unextended first leash section.

Celery variety '51-7 ips 1'

A celery cultivar, designated 51-7 ips 1, is disclosed, the cultivar is, for larger frame size and heavier weight, short core length, savoyed and glossy leaf color, corky root rot resistance, no fringe burn on mature leaves and also yellower heart leaf color with solid midribs. The invention relates to the seeds of celery cultivar 51-7 ips 1, to the plants of celery cultivar 51-7 ips land to methods for producing a celery plant by crossing the cultivar 51-7 ips 1 with itself or another celery cultivar.

Multileaf spinach

The invention relates to spinach plants comprising a multileaf trait. The invention provides methods and compositions for generating such spinach plants with multileaf trait.

Wireless solenoid mesh network

There is provided an irrigation system with a plurality of solenoid valves. The solenoid valves each include a wireless transceiver that communicates with one another to form a mesh network.

Fertilizer tube system

A fertilizer tube system for efficiently dispensing and placing fertilizer within a furrow to minimize germination injury. The fertilizer tube system generally includes a fertilizer tube having an input opening at an upper end of the fertilizer tube and an output opening at a lower end of the fertilizer tube, a tab attached to the fertilizer tube between the input opening and the output opening and a guard scraper attached to a lower portion of the fertilizer tube.

Floor treatment apparatus

The present invention relates generally to an apparatus for cleaning or otherwise treating a floored surface that includes a platform adapted to support the weight of an operator. In addition, one embodiment of the present invention is capable of generally performing 360 degree turns to facilitate the treatment of difficult to access portions of the floored surface..
Klemm+sohn Gmbh & Co. Kg

Alteration of tobacco alkaloid content through modification of specific cytochrome p450 genes

Compositions and methods for reducing the level of nornicotine and n′-nitrosonornicotine (nnn) in nicotiana plants and plant parts thereof are provided. The compositions comprise isolated polynucleotides and polypeptides for cytochrome p450s that are involved in the metabolic conversion of nicotine to nornicotine in these plants.
Klemm+sohn Gmbh & Co. Kg

Hitachi Automotive Systems, Ltd.

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Association For The Advancement Of Tissue Engineering And Cell Based Technologies & Therapie

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Endorecherche, Inc.

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Basf Se

. .

Container

A container is described having a base, sides and a top, the base, sides and top together defining a void within which items can be located in use, an electromagnetic shield fully surrounding at least part of the void to provide an electromagnetic shield between an exterior of the container and items located within the said part of the void, an antenna located within the said part of the void and a signal generator connected to the antenna and operable to apply a signal to the antenna to cause the transmission of an impeding signal within the said part of the void to impede the reception of signals transmitted from locations external to the container by items located within the said part of the void.. .
Kirintec Limited

Tamper evidence child resistant liquid containment packaging

A tamper evidence child resistant liquid containment packaging comprising a container and a corresponding capping assembly that inhibits unauthorized removal of capping assembly and indicates tampering. The container stores liquid.
Victorie Packaging Corp.

Tamper-evident thermoformed packaging

A package having a lid seated on a base where the edge of the seated lid is generally inaccessible, and where the edge is made accessible by a movement of a tamper-evident tab. The base and lid are configured so that opening of the tamper-evident tab locks the tab in the opened position.
Display Pack, Inc.

Reclosable pouch having a clicking closure device

A reclosable pouch includes a first bag wall. A second bag wall opposing the first bag wall is joined to the first bag wall to form an interior of the pouch with an opening to the interior.
S.c. Johnson & Son, Inc.

Easy open plastic bags

A woven laminated plastic bag having an easy open feature is provided. The easy open feature is generally defined by a weakened portion in the bag.
Polytex Fibers Corporation

Heavy duty folded corrugated pallet

The invention generally relates to devices used for material handling, such as specifically, pallets and skids. More specifically, the present invention is directed toward a folded corrugated pallet.
Preferred Packaging Solutions, Inc.

Light weight folded corrugated pallet

The invention generally relates to devices used for material handling, such as specifically, pallets and skids. More specifically, the present invention is directed toward a folded corrugated pallet including a body defined by a single sheet of corrugated cardboard.
Preferred Packaging Solutions, Inc.

Folded corrugated pallet

The invention generally relates to devices used for material handling, such as specifically, pallets and skids. More specifically, the present invention is directed toward a folded corrugated pallet.
Preferred Packaging Solutions, Inc.

Multi-layer container and production method therefor, single-layer container production method, and recycled polyester resin production method

An object of the present invention is to provide a multilayer container in which yellowing of a regenerated polyester resin at the time of recycle is suppressed and a method for producing the same as well as a method for producing a single-layer container. Furthermore, another object of the present invention is to provide a method for producing a regenerated polyester resin from the foregoing multilayer container and single-layer container.
Mitsubishi Gas Chemical Company, Inc.

Interplanetary spacecraft using fusion-powered thrust

A spacecraft propulsion system operated in the presence of an ambient flux of cosmic rays is provided, wherein the cosmic rays interact with deuterium-containing nuclear micro-fusion fuel material to generate products having useful kinetic energy. The propulsion system comprises a supply of the deuterium-containing particle fuel material, along with means (such as a gun) for projecting the material (e.g.

Systems and methods for recovering and controlling post-recovery motion of unmanned aircraft

Systems and methods for recovering unmanned aircraft and controlling post-recovery motion of the aircraft are disclosed herein. An aircraft recovery system for handling an unmanned aircraft in accordance with one embodiment of the disclosure includes a base portion and an elongated aircraft capture member having a first end movably coupled to the base portion and a second, free end opposite the first end.
Insitu, Inc.

Avionic display generating vertical situation displays including instability prediction and avoidance symbology

Avionic display systems and methods are provided for generating avionic displays including instability prediction and avoidance symbology, such as dynamically-adjusted drag device deployment cues. In one embodiment, the avionic display system includes a controller and an avionic display device, which is coupled to the controller and on which an avionic display, such as a vertical situation display (vsd), is generated.
Honeywell International Inc.

Aerodynamic control surface movement monitoring system for aircraft

Actuator systems and methods for controlling aerodynamic control surfaces of aircraft including a first actuator receiving a first input and a first linear translation element that moves based thereon, the first linear translation element operably connected to a first portion of the control surface. A first sensor assembly is disposed relative to the first actuator that generates an output based on a displacement of the first translation element.
Hamilton Sundstrand Corporation

Semi-automated lock assembly

A semi-automated lock assembly is provided and includes a housing, a pawl rotatably coupled to the housing to occupy and rotate between retracted and erected positions relative to the housing and a torque generating assembly. The torque generating assembly is secured within the housing and is coupled to the pawl to apply torque assist to an erecting rotation thereof without opposing a retracting rotation thereof..
Goodrich Corporation

Systems and methods for in-flight retrieval of unmanned aerial vehicles

Presently disclosed systems and methods are configured for in-flight retrieval of unmanned aerial vehicles (uavs). Such systems generally include a retrieval ramp, a tether system including a tether, and a capture connector.
The Boeing Company

Tiltrotor aircraft having rotatable wing extensions

A pylon assembly for a tiltrotor aircraft includes a fixed pylon having an outboard end. A rotor assembly is rotatably coupled to the fixed pylon and is operable to rotate between a a vertical takeoff and landing orientation and a forward flight orientation.
Bell Helicopter Textron Inc.

Rotorcraft anti-torque and directional control using a centrifugal blower

In one embodiment, a rotorcraft comprises a fuselage, a tail boom, a rotor system, and a centrifugal blower system. The centrifugal blower system comprises a centrifugal blower configured to generate thrust using an airflow, wherein the centrifugal blower is located within the tail boom.
Bell Helicopter Textron Inc.

Multi-architecture modular unmanned aerial system

Disclosed herein is a modular aerial vehicle system having a fuselage module configured to couple with a plurality of lift generation modules. The modular aerial vehicle system may comprise a fuselage module and a lift generation module.
Aurora Flight Sciences Corporation

Galley trolley compartment doors

Embodiments of the present disclosure relate generally to galley trolley compartment doors that replace traditional trolley retainer latches used to secure trolleys when positioned in galley compartments. The galley trolley compartment doors are designed with engaging arms that help secure the trolleys in place under required loads.
Driessen Aerospace Group N.v.

System, widespread commercialization of hydrogen as a carbon-free alternative fuel source

A system for transporting hydrogen from where it can be economically made to where it is most needed using airships. Green technologies can be used to generate electricity near to the primary energy sources.

Monitoring energy usage of a surface maritime vessel

A system (102) is configured to monitor energy usage of a surface maritime vessel (100). The system comprises a device (102a) configured to receive characteristic data representing at least one operating characteristic of the vessel, and a device (102a) configured to receive model data representing at least one energy usage model for the vessel.
Bae Systems Plc

Vehicle component

A vehicle component that can include a suspension system for bicycles, electric bicycles, or electric scooters. The vehicle component can include a sliding four-bar system with a link pivotally connecting a swing arm to the front triangle and a sliding link slidably connecting the swing arm to a front triangle bottom portion.

Personal transportation vehicle

A personal transportation vehicle. The personal transportation vehicle provides an outer and inner shell having a rotor assembly supported between.

Splash-protection device for a wheel-mounted vehicle, and assembly having such device

The device (1) comprises resilient shield (2) return means in the high position and a surface carried by the shield (2) and suitable for being exposed to the airflow generated when the wheeled vehicle (20) is moving forwards, said surface being configured, under the action of said airflow, to enable the shield (2) to move in a direction that is opposite to the direction of the return force.. .

Steering device and producing the same

A spacer is interposed between a rim core metal and an electronic part, so that the electronic part can be easily disposed. An opening is formed in the spacer such that the opening is positioned to face an overflow portion that is formed in a mold for molding of a resin layer and that is provided for a fluid synthetic resin raw material to overflow.
Nihon Plast Co., Ltd.

System and method integrating an energy management system and yard planner system

A system and method identifies vehicles to be included in a multi-vehicle system that is to travel along one or more routes for an upcoming trip, and determines plural different potential builds of the multi-vehicle system. The different potential builds represent different sequential orders of the vehicles in the multi-vehicle system.
General Electric Company

Vehicle state estimation apparatus and method

The present disclosure relates to an apparatus (1) for estimation of a vehicle state. The apparatus (1) includes a controller (21) configured to determine a first estimation of the vehicle state in dependence on at least one first vehicle dynamics parameter.
Jaguar Land Rover Limited

Server and controlling regenerative braking of eco-friendly vehicle

A server and a method for automatically controlling regenerative braking of an eco-friendly vehicle are provided. A regenerative braking level is calculated by considering driving information and a driving environment of a vehicle using a regenerative braking controlling server.
Kia Motors Corporation

Internal combustion engine control device

The internal combustion engine control device according to the present invention is provided with the generator driven by the exhaust gas of the internal combustion engine, and includes an exhaust amount control unit which increases the amount of the exhaust gas supplied to the generator in a coasting state.. .

Travel control method and travel control apparatus

A travel control method includes a detector that detects information on lane boundary lines of a lane around a subject vehicle as real boundary line information from an actual environment around the subject vehicle. The travel control method also includes integrating the real boundary line information and map boundary line information to generate integrated boundary line information.
Nissan Motor Co., Ltd.

System for parking a vehicle

A system for parking a vehicle includes a mobile terminal. The mobile terminal includes at least one first image acquisition device for acquiring first image data, a first computing unit which is designed to receive the first image data from the first image acquisition device and to generate information indicating a parking position on the basis of the first image data, and a transmission device for transmitting the information.
Bayerische Motoren Werke Aktiengesellschaft

Controller for vehicle

A controller is applied to a vehicle including an engine (11) and a motor generator (12 and 13) as power sources of the vehicle and a battery (20) that transfers power with the motor generator. The controller charges the battery with a regeneration power that is a power regenerated by the motor generator when the vehicle is decelerated.
Denso Corporation

Engine oil dilution control in a hybrid vehicle

A vehicle includes an engine and a controller programmed to, responsive to an estimated oil dilution level of the engine exceeding a first threshold, issue commands such that regenerative braking is inhibited to increase a temperature of the engine, and responsive to the estimated oil dilution level falling below the first threshold, discontinue issuing the commands.. .
Ford Global Technologies, Llc

Electric brake system

Disclosed is an electronic brake system. The electronic brake system includes a master cylinder connected to a reservoir in which brake fluid is stored and configured to discharge the brake fluid according to a pedal effort of a brake pedal, the master cylinder including first and second master chambers and first and second pistons provided in the master chambers; a hydraulic pressure supply device activated by an electrical signal to generate a hydraulic pressure; a hydraulic pressure control unit configured to transfer, to a plurality of wheel cylinder provided in wheels, a hydraulic pressure discharged from the hydraulic pressure supply device; first and second backup flow paths configured to connect the first and second master chambers to the hydraulic pressure control unit; and first and second cut valves configured to selectively open and close the first and second backup flow paths, wherein one or both of the first backup flow path and the second backup flow path are connected to the first or second master chamber and any one of the plurality of wheel cylinders..
Mando Corporation

Braking device for vehicle and vehicle including braking device

A braking device for a vehicle includes a plurality of braking force generators; a steering assist device; a yaw rate detecting unit; and a control device. The control device is configured to perform control such that, in a case where the plurality of braking force generators perform a braking operation and there is a malfunctioning braking force generator, braking forces of the plurality of braking force generators other than the malfunctioning braking force generator are maintained or increased when an acquired value of an actual yaw rate acquired from the yaw rate detecting unit is equal to or less than a reference value, and a steering torque is applied to a steering system in a direction in which the actual yaw rate decreases when the acquired value of the actual yaw rate is larger than the reference value..
Toyota Jidosha Kabushiki Kaisha

Wiperless cleaning system for transparent surfaces using air jets

A cleaning system for cleaning a surface of a windshield, window, light or side mirror of a vehicle or the surface of a window of a building includes at least one air flow generator, a plurality of nozzles, and a system of pipes and/or tubes to distribute air flow to the nozzles. The plurality of nozzles form a curved array of nozzles over the surface such that air jets are ejected by the nozzles and distributed over the surface..
Jetwipe 2017 Ivs

Dynamic sensor selection for self-driving vehicles

A self-driving vehicle (sdv) can operate by analyzing sensor data to autonomously control acceleration, braking, and steering systems of the sdv along a current route. The sdv includes a number of sensors generating the sensor data and a control system to detect conditions relating to the operation of the sdv, such as vehicle speed and local weather, select a set of sensors based on the detected conditions, and prioritize the sensor data generated from the selected set of sensors to control aspects relating to the operation of the sdv..
Uber Technologies, Inc.

Viewing device for vehicle

A viewing device for a vehicle is provided with plural cameras, an image generation unit, a display and a switching control unit. The plural cameras have different imaging ranges.
Toyota Jidosha Kabushiki Kaisha

Automobile or vehicle proximity sensor and warning display mounted on outside rear view mirror

The automobile proximity sensor and warning display is mounted on an outside rear view mirror of a vehicle. A flat base plate, adhered to the outside mirror, coacts with a removable body on a front side of the base.
Alexilex 700 Llc

Viewing device for vehicle

A viewing device for a vehicle, comprises: a plurality of imaging apparatuses that differ in imaging range; an image generation apparatus that, on the basis of images imaged by one or a plurality of the imaging apparatuses, generates a viewing image that is a composite of: an image to a vehicle rear, an image of a vehicle structure, the image being semi-transparent, and an image of a vehicle occupant on a rear seat; and a displayer that displays the viewing image.. .
Toyota Jidosha Kabushiki Kaisha

System and pedestrian alert

A system and method for pedestrian alert that derives a pedestrian path representing a projected path for a pedestrian, derives a vehicle path representing a projected path for a motor vehicle, determines an intersection of the pedestrian path and the vehicle path, determines alert characteristics responsive to the determined intersection, and generates an alert that is emitted from the vehicle responsive to the determined alert characteristics. The system and method for pedestrian alert may be built, installed or implemented in a motor vehicles that is operated in environments where the motor vehicle may be in close proximity to pedestrians.
2236008 Ontario Inc.

Agricultural dump cart

An agricultural dump cart including a frame, ground conveyance devices carrying the frame, a dump bed, a dumping mechanism and at least one live wall mechanism. The dump bed is coupled to and carried by the frame, and the dump bed has a non-dumping position and a dumping position.

Seat sliding device for vehicle

A seat sliding device for a vehicle includes a sliding load adjusting mechanism. The sliding load adjusting mechanism includes a support member, which is fixed to a first rail that is one of a lower rail and an upper rail, and a pressing member, which is movably supported by the support member.
Aisin Seiki Kabushiki Kaisha

Supply medium exchange system for mobile units

Provided are embodiments of a supply medium exchange system. The system includes at least one supply medium exchange station having at least one supply medium exchange interface.
Innogy Innovation Gmbh

Power generating a vehicle

The present disclosure relates to the field of power electronics and provides a power generating system and method for a vehicle. The present disclosure provides an alternative system for charging an energy storage device that is used to drive a vehicle and also to reduce dependency of the vehicle on the energy storage device..

Braking device for vehicle

A braking device for a vehicle includes a friction brake device, a regeneration bake device, a control portion which controls the friction braking force and the regeneration braking force through a cooperative control and a state judging portion which judges whether a vehicle state is in a stopped state or a non-braking operation state where the braking operation is not performed, the control portion executes a factor change control which suppresses an increase of change inclination of the friction braking force by changing a factor relating to a friction used when the hydraulic pressure is converted into the friction braking force to an increasing side and returns the factor to a value at a non-operation of the factor change control when the vehicle state is judged to be in the stopped state or the non-braking operation state by the state judging portion.. .
Toyota Jidosha Kabushiki Kaisha

Regenerative braking device and dump truck

In a regenerative braking device of a dump truck comprising an engine, a first generator and a second generator driven by the engine, at least one travel motor driven by generated electric power of the first generator and at least one fan motor to which generated electric power of the second generator is inputted via a first rectifier circuit, the regenerative braking device comprises: a resistive element to which regenerating electric power from the at least one travel motor in regenerative braking is supplied and which is cooled by at least one fan driven by the at least one fan motor and converts electric energy into heat energy and dissipates heat; and a dc/dc converter that inputs a part of the regenerating electric power which is supplied to the resistive element to an output line of the first rectifier circuit via a second rectifier circuit.. .
Hitachi Construction Machinery Co., Ltd.

Fuel tank system

A tank passage is connected at its one end to a fuel tank, which stores fuel. A canister is connected to the other end of the tank passage and adsorbs evaporated fuel generated by evaporation of fuel in the fuel tank.
Denso Corporation

Electric heater device, in particular for vehicles

A heater device comprises a supporting body (5) and a plurality of heating elements in the supporting body (5). Each heating element includes a first electrode (14), a second electrode (15), and a material having a ptc effect (16) arranger at least in part between the two electrodes (14, 15).
Eltek S.p.a.

Vehicular heat management device

A vehicular heat management device includes a first heat source, a second heat source, a heater core, a first heat medium pathway, a second heat medium pathway, a heater core pathway, a switching portion, and a control unit. The first heat source is provided in the first heat medium pathway, and the second heat source is provided in the second heat medium pathway.
Toyota Jidosha Kabushiki Kaisha

Temperature control system providing conductive heating and cooling for a seat

A temperature control system for a vehicle seat includes a finish trim layer, a thermally conductive panel in thermal contact with the finish trim layer, a thermal device generating a temperature gradient, and a heat transfer structure connecting the panel and the thermal device. The panel and the heat transfer structure are adapted to together thermally conduct the quantity of heat between the finish trim layer and the thermal device..
Lear Corporation

Active roll stabilizer

Disclosed herein is an active roll stabilizer. The active roll stabilizer includes a pair of stabilizer bars installed between left and right wheels of a vehicle and an actuator which connects the pair of stabilizer bars and transmits a rotational force to the pair of stabilizer bars, wherein the actuator includes a motor configured to generate the rotational force, a housing coupled to a portion between the pair of stabilizer bars and having the motor disposed inside the housing, a damping part disposed on an extension line of a rotational shaft of the motor inside the housing and configured to absorb vibrations generated at the motor and the pair of stabilizer bars, and a torque measurement sensing part configured to measure a torque transmitted by the rotational force inside the damping part..
Mando Corporation

Vehicle twist axle assembly

The twist axle assembly includes a twist beam which is made of a single integral piece and extends along a length between opposite ends. The twist beam has a middle portion which extends in a first direction and a pair of end portions which extend at least partially in a second direction that is generally transverse to the first direction to reduce twisting stresses within the end portions during operation of the twist axle assembly..
Magna International Inc

Elastomer coupling and associated roll stabilizer

An elastomer coupling for an electromechanical actuator, having a drive part and a driven part, wherein either the drive part or the driven part has multiple radially outwardly extending webs arranged so as to be distributed about an axis of rotation, and the respective other part has radially inwardly extending webs arranged on the inner side of a tubular body, wherein a radially inwardly and a radially outwardly extending web engage into one another and form a pocket in which there is received an elastic molded body produced from an elastomer, wherein, in at least one pocket, there is received a spring element which generates a pretensioning force, which spring element is attached either to an inwardly extending or to an outwardly extending web and is spring-loaded against an adjacent web.. .
Schaeffler Technologies Ag & Co. Kg

Model based tire wear estimation system and method

A tire wear estimation system is provided. The system includes at least one tire that supports a vehicle.
The Goodyear Tire & Rubber Company

Pocket with stress relief

A pocket structure including a first panel, and a second panel coupled to the first panel to define a pocket with the first panel. The second panel has an opening intersecting an outer edge thereof.
Acco Brands Corporation

Print data generation device, generating print data, program, and printing apparatus

A print data generation device includes a control unit that generates print data, and the control unit calculates a label length for a label to be printed on the basis of the first print data, acquires a maximum label length, generates first print data in a case in which a calculated label length, which is a label length that is calculated, does not exceed the maximum label length, and generates second print data, the label length of which is equivalent to the maximum label length, in a case in which the calculated label length exceeds the maximum label length.. .
Seiko Epson Corporation

Ink drying device and printing system

An ink drying device dries ink injected onto a recording medium. The ink drying device includes a main body including a counter plate facing the recording medium and including an inner space, and a heat generator located in the inner space of the main body to generate heat.
Roland Dg Corporation

Information processing device

An information processing device is connected to a first reading device to read a recording medium to generate first data, a writing device to write on the recording medium based on second data, and a second reading device to read the recording medium to generate third data. The information processing device includes a first retrieval unit to obtain the first data; an identifying unit to identify the recording medium based on the first data; a second retrieval unit to obtain, upon detecting that the writing device writes on the recording medium, the third data; a determination unit to determine whether the second data differs from the third data; a calculation unit to calculate a number of times of writing on the recording medium; a storage unit to store the calculation value; and an evaluation unit to evaluate the recording medium based on the calculation value..

Inkjet printer

An inkjet printer includes: a pressurized space and a depressurized space for circulation of ink along a circulation path; a main connection path and an adjustment path connecting the pressurized space and the depressurized space to each other; an air pump configured to send air from the depressurized space to the pressurized space though the main connection path or the adjustment path; a changeover device configured to change over between the main connection path and the adjustment path; and a controller. The controller drives the air pump with the main connection path being set to generate preset pressures respectively in the pressurized space and the depressurized space and then controls the air pump with the adjustment path being changed over to maintain pressures in the pressurized space and the depressurized space respectively at the preset pressures..
Riso Kagaku Corporation

Liquid ejection head, liquid ejection apparatus, and supplying liquid

A liquid ejection head includes an ejection opening; a passage in which an energy generation element is disposed; an ejection opening portion that allows communication between the ejection opening and the passage; a supply passage for allowing the liquid to flow into the passage; and an outflow passage for allowing the liquid to flow out to the outside. An expression of h−0.34×p−0.66×w>1.7 is satisfied when a height of the passage is set to h, a length of the ejection opening portion is set to p, and a length of the ejection opening portion is set to w..
Canon Kabushiki Kaisha

Driving waveform generating device, liquid discharge head, inkjet recording apparatus, and driving waveform generating method

In accordance with an embodiment, a driving waveform generating device comprises an input module, a setting module, and a generating module. The input module inputs setting data for setting a driving waveform.
Toshiba Tec Kabushiki Kaisha

Inkjet head control apparatus and inkjet printer

An inkjet head control apparatus includes a mother substrate, a plurality of daughter substrates connected to a plurality of connectors of the mother substrate, each daughter substrate having a different built-in address, and a communication circuit on the mother substrate and configured to select an address of one of the plurality of daughter substrates, and transmit a control signal including the selected address and information for controlling power supply to an inkjet head to the plurality of connectors. Each of the plurality of daughter substrates includes a determination circuit configured to determine whether or not the selected address corresponds to the built-in address of the daughter substrate, and a voltage generating circuit configured to generate a direct current (dc) voltage for driving the inkjet head based on the control signal when it is determined that the selected address corresponds to the built-in address..
Toshiba Tec Kabushiki Kaisha

Liquid discharging apparatus

A liquid discharging apparatus includes a print head that discharges a liquid, a carriage that is mounted on the print head, a control signal generation circuit, a drive signal generation circuit, a first cable through which a drive signal generation control signal is transmitted to the drive signal generation circuit, a second cable through which a drive signal is transmitted to the print head, a control circuit substrate on which the control signal generation circuit is provided, and a drive circuit substrate on which the drive signal generation circuit is provided. The shortest distance between the control circuit substrate and the carriage is longer than the shortest distance between the drive circuit substrate and the carriage.
Seiko Epson Corporation

Liquid discharging apparatus and circuit substrate

A liquid discharging apparatus includes a print head that has a driving element and discharges a liquid, a drive signal generation circuit that generates the drive signal based on a drive signal generation control signal for controlling generation of the drive signal, and a drive circuit substrate on which the drive signal generation circuit is provided. The drive circuit substrate has an input connector that inputs the drive signal generation control signal into the drive circuit substrate and an output connector that outputs the drive signal from the drive circuit substrate.
Seiko Epson Corporation

Modular wall panels and planar structures

A modular glass panel comprising a glass structure having at least one thin glass sheet having a thickness ranging from about 0.5 mm to about 2.0 mm, a backing frame positioned adjacent the glass structure and situated along the perimeter of the glass structure, and a polymer layer intermediate the glass structure and backing frame to adhere the glass structure together with the backing frame. The glass structure can further comprise the at least one thin glass sheet and a second glass sheet having a polymer interlayer therebetween.
Corning Incorporated

Method and forming containers

A system is claimed for forming a container from a tubular blank comprising a plurality of panels and flaps interconnected to provide a generally flattened tubular configuration. A first and second panels are provided with the second panel being rotatable relative to the first panel.

Apparatus for sealing and inflating motor vehicle tires

A device for sealing and inflating motor vehicle tires, wherein the device has, in a housing, a compressor which is driven by a motor, preferably an electric motor, and which serves for generating the sealing or pump pressure, and the device has a connector for a sealant container, a valve and distributor unit for sealant and pressurized gas, and furthermore connecting means such as hoses and lines, and also switching, control and display devices for the operation of the device, wherein the device furthermore comprises a manually actuatable pressure discharge valve for decreasing the tire pressure, wherein the pressure discharge valve is configured such that, when the sealant container is connected and/or during the delivery of sealant from the sealant container into the tire, an actuation, or a dissipation of the pressure, is prevented.. .
Continental Reifen Deutschland Gmbh

Methods of making a specimen with a predetermined wrinkle defect

In a first aspect, there is a method of making a specimen with a predetermined wrinkle defect, the steps including orienting a composite material around a layup tool at a wrap angle to form a closed loop; and generating at least one wrinkle with a predetermined characteristic in a portion of the closed loop to form a specimen. The predetermined characteristic is at least one of the following: wrinkle location, an outward wrinkle, an inward wrinkle, a wrinkle width, a wrinkle height, and a wrinkle length.
Bell Helicopter Textron Inc.

Ultrasonic welding of dissimilar sheet materials

A ultrasonic welding method of joining dissimilar-material workpieces, such as sheet materials, and the joined components formed thereby. The method includes applying ultrasonic energy to a thermoplastic piece to fill a hole of a dissimilar piece to form a weld point that is made up with polymer from the thermoplastic piece.
Gm Global Technology Operations Llc

Device and generative layer-building process for producing a three-dimensional object by multiple beams

The invention refers to a device and a method of manufacturing a three-dimensional object. The object (3) is manufactured on at least one support (2) movable in height.
Eos Gmbh Electro Optical Systems

3d printing of an intraocular lens having smooth, curved surfaces

A continuous additive fabrication system comprises a bath of photopolymer resin and a light source assembly having a light source and a motorized variable aperture. The light source assembly is operable to generate a focus point in the bath of photopolymer resin, the shape of the focus point at a curing plane within the bath of photopolymer resin corresponding to the shape of the motorized variable aperture.
Novartis Ag

Extrudable polymer composites with membrane barrier properties

The present disclosure generally relates to extrusion die systems. In particular, the present disclosure relates to the cyclical extrusion of materials to generate small sized grain features, generally in the range of nanosized grain features, in a tubular or profile shape, in which the individual nanolayers possess pores and/or polymer crystals oriented parallel to the extrusion flow direction and including products with enhanced permeation properties..
Guill Tool & Engineering Co., Inc.

Controller arrangement for injection molding system

An injection molding apparatus (10) comprising a signal converter (1500) interconnected to a machine controller (mc) of an injection molding machine (imm) that generates standardized signals (vps), the signal converter (1500) receiving and converting the standardized signals (vs) to a command signal (mopcs, pdcvs) that is compatible with a signal receptor or interface of an electrically powered actuator (940e, 941e, 942e) or a signal receptor, interface or driver of a proportional directional control valve (v, v1, v2) that drives a fluid driven actuator (940p, 941p, 942p) to respectively operate the electrically powered actuator (940e, 941e, 942e) or the proportional directional control valve (v, v1, v2) to move in a direction that operates to either begin an injection cycle and to end an injection cycle.. .
Synventive Molding Solutions, Inc.

Modular press

A modular press suitable for use in the manufacture of ewc products may include a plurality of frame modules coupled together and aligned along a feed path axis. Each frame module may have a generally planar body supported on a corresponding pair of bases, an elongate aperture, an upper and a lower platform within the aperture, and a platen between the platforms.
Usnr, Llc

Apparatus and methods for haptic training of robots

Robotic devices may be trained by a trainer guiding the robot along a target trajectory using physical contact with the robot. The robot may comprise an adaptive controller configured to generate control commands based on one or more of the trainer input, sensory input, and/or performance measure.
Brain Corporation

Assist device

An assist device includes a body wearing unit and an actuator unit. The actuator unit includes an output link configured to pivot about a joint of an assist target body part and to be attached to the assist target body part; an actuator including an output shaft configured to generate an assist torque via the output link; a torque determination unit configured to determine a combined torque obtained by combining a user torque and the assist torque from the output shaft, the user torque being input from the output link when the user causes the assist target body part to pivot; a correction unit configured to calculate a correction amount for the determined combined torque; and a pivot angle control unit configured to control a pivot angle of the output shaft based on the determined combined torque and the calculated correction amount..
Jtekt Corporation

Handheld power tool

A handheld power tool includes a torque coupling adjustable by the operator, as well as a gear unit for transmitting a torque generated by a drive motor to a drive shaft. The gear unit is advantageously a planetary gear unit; the torque coupling being constructed in such a manner, that in response to slippage of the torque coupling, a coupling component follows a displacement path.
Robert Bosch Gmbh

Creating radial slots in a subterranean formation

A laser cutting apparatus conveyable within a casing lining at least a portion of a wellbore that extends into a subterranean formation. The laser cutting apparatus includes a housing, a deflector, a motor, a sensor, and a processing device.
Schlumberger Technology Corporation

Tangentially mounted cutting insert with angled seating surface and recessed clearance surface

A milling insert includes a first axial face, a second axial face, a first radial face, a second radial face parallel with the first radial face, a cutting face, and a generally v-shaped seating face formed with a first seating surface and a second seating surface. The first axial face defines a secondary clearance surface that is at least partially axially recessed from the first axial face and oblique to the first radial face.
Kennametal Inc.

Crayon carving device

Devices, kits, and methods for making a carved crayon are provided. In one aspect, a crayon carving device includes a base, a pantograph armature coupled to the base, a crayon positioner, and at least one guide template parallel to the crayon positioner.
Crayola, Llc

Multi-step joining device and joining method therefor

A joining device, in particular a self-piercing rivet tool, is disclosed that is operated with the assistance of different drive steps. These drive steps comprise at least one movement step with a fast punch speed, and a power step with a low punch speed and strong punch force.
BÖllhoff Verbindungstechnik Gmbh

Batch processing load lock chamber

Embodiments of the disclosure generally relate to an improved batch processing load lock chamber, a cluster tool having the same and a method of using the improved load lock chamber to clean a plurality of substrates disposed within. In one embodiment, a load lock chamber includes a chamber body, a cassette disposed in the chamber body, a remote plasma source, a plurality of inlet nozzles and a plurality of outlet ports.
Applied Materials, Inc.

Compositions and methods for gras compliant cleaners for ethanol production equipment

The present technology relates to various cleaning compositions and their methods of use in industrial facilities such as ethanol and biofuel producing vessels. Cleaning compositions according to the present technology may be generally recognized as safe (gras) as designated by the u.s.
Clear Solutions Usa, Llc

Stain removal device

A stain removal device, a head portion having a beating surface; a vibration unit which is located on an extension line of an axis of the head portion orthogonal to the beating surface and vibrates the head portion in an axis direction through driving of a solenoid actuator; and a liquid supply unit which has a liquid accommodating portion capable of accommodating liquid and supplies the liquid in the liquid accommodating portion to the beating surface through vibration of the head portion generated by the vibration unit.. .
Qingdao Haier Washing Machine Co., Ltd.

Modular batch plant for granular products

A portable processing plant for processing granular material is provided. The portable plant includes a plurality of portable processing modules configured to be stacked vertically to allow for a vertically downward progression of the generally granular material through the portable processing plant.
Red Flint Group, Llc

Compact ultrasonically pulsed waterjet nozzle

A pulsed waterjet apparatus comprising a water pump for generating a pressurized waterjet, an ultrasonic signal generator for generating an ultrasonic signal and an ultrasonic nozzle comprising an ultrasonic transducer for converting the ultrasonic signal into vibrations that pulse the pressurized waterjet to generate a pulsed waterjet, an exit orifice through which the pulsed waterjet exits and an inflow inlet axially aligned with the exit orifice.. .
Vln Advanced Technologies Inc.

Angularly adjusted spray nozzle

According to some illustrative embodiments, an angularly adjustable spray nozzle is employed that includes: a base section having a water flow path extending lengthwise there-through; a head section aligned at an end of the base section and rotatably mounted to the base section; wherein a flow path through the base section is inclined at an angle to a flow path through the head section such that when the head section is rotated a predetermined extent relative to the base section, the spray device is moved between a substantially straight configuration of the head section with respect to the base section and an angular configuration of the head section with respect to the base section; wherein the head section includes a rotatable turret assembly having a plurality of selectable spray type discharge ports and a sleeve to which the rotatable turret assembly is mounted, the rotatable turret assembly including labels on a periphery thereof corresponding to respective ones of the selectable spray type discharge ports, and the sleeve having a plurality of windows through which the labels are viewed when aligned; and wherein the spray device is configured such that when the spray device is oriented in a generally horizontal use position a respective one of the labels corresponding to a selected spray type is displayed within a respective one of the windows that is located at a top side of the sleeve whether the spray device is in the substantially straight configuration or in the angular configuration.. .
Melnor, Inc.

Nozzle and liquid material discharge device provided with said nozzle

A nozzle capable of removing a surplus liquid material, which is adhered to outer surfaces of the nozzle and which affects a discharge operation, without undergoing a special process, and a liquid material discharge device provided with the nozzle. The nozzle (1) includes a body (2) having a liquid inflow space, and a discharge tube (4) communicating with the liquid inflow space and extending downwards from the body (2).
Musashi Engineering, Inc.

Detection of cyclone wear or damage using individual cyclone overflow measurement

Apparatus features a signal processor or signal processing module configured to: receive signaling containing information about an acoustic noise profile that is directly measured and generated by a slurry hitting a probe configured in a part of a cyclone; and determine corresponding signaling containing information about the status of the part of the cyclone, based upon the signaling received. The signal processor or signal processing module is configured to provide the corresponding signaling, including where the corresponding signaling provided contains information about whether the part of the cyclone is damaged or worn.
Cidra Corporate Services Inc.

Systems and methods for collecting a species

Systems and methods related to the collection of a species from a gas stream are generally provided. The systems and methods described herein may allow for collection of a species such as a fluid (e.g., water) with a relatively high collection efficiency.
Massachusetts Institute Of Technology

Ion filtration air cleaner

An ion filtration air cleaning device for cleaning air by use of electrostatic ion attraction. Air having suspended particles is drawn into the device through an inlet by a fan.
Helen Of Troy Limited

Device and flow and bead speed characterization in microfluidic devices

Method, apparatus, and computer program product for a microfluidic channel having a cover opposite its bottom, such that the cover allows visual inspection inside the channel, and having electrodes with patterned planar conducting materials, integrated onto its bottom. Using the planar conducting materials, once a fluid sample with suspended microparticles is applied into the channel, highly localized modulated electric field distributions are generated inside the channel and the fluid sample.
International Business Machines Corporation

Catalyst composition containing phosphorous-based ligand and hydroformylation using same

The present invention relates to a catalyst composition including a phosphorous-based ligand, and a hydroformylation method using the catalyst composition. More particularly, the present invention relates to a catalyst composition, which includes two different kinds of monocoordinated phosphine ligands and a transition metal catalyst, and a hydroformylation method using the catalyst composition.
Lg Chem, Ltd.

Screw machine and the processing of material to be processed

A screw machine includes an inductive heating device for the processing of material to be processed. The inductive heating device is used to heat the material in a heating zone.
Coperion Gmbh

In vitro evolution in microfluidic systems

The invention describes a method for isolating one or more genetic elements encoding a gene product having a desired activity, comprising the steps of: (a) compartmentalising genetic elements into microcapsules; and (b) sorting the genetic elements which express the gene product having the desired activity; wherein at least one step is under microfluidic control. The invention enables the in vitro evolution of nucleic acids and proteins by repeated mutagenesis and iterative applications of the method of the invention..
President And Fellows Of Harvard College

Refrigerator

Provided is a refrigerator including: a main body; a storage compartment formed in the main body; a door that opens/closes the storage compartment; a general water tank in which general water supplied from an external water supply source is stored; a mixing tank in which general water supplied from the general water tank is mixed with carbon dioxide (co2) so that carbonated water is made and stored; a dispenser that provides general water supplied from the general water tank to an outside and provides carbonated water supplied from the mixing tank to the outside of the refrigerator; and an ice-making machine that makes general ice by receiving general water from the external water supply source or the general water tank and makes carbonated ice by receiving carbonated water from the mixing tank, thereby providing general water, carbonated water, general ice, and carbonated ice through the dispenser.. .
Samsung Electronics Co., Ltd.

Homogeneous fiber reinforced pvdf hollow fiber membrane and preparation method thereof

A homogeneous fiber reinforced pvdf hollow fiber membrane and a preparation method thereof are provided. The membrane includes a hollow tubular reinforcement made of pvdf fibers and a polymer separation layer made of pvdf casting solution; wherein the polymer separation layer casting solution comprises 4-25% pvdf resin, 5-20% pore-forming agent, 0-3% inorganic particles and 52-91% solvent according to mass fraction.
Tianjin Polytechnic University

Process for making membranes

A membrane contains a polymer composition is described. The polymer composition contains a) at least one polymer of pa, pva, cellulose ca, cta, ca-triacetate blend, cellulose ester, cellulose nitrate, regenerated cellulose, aromatic, aromatic/aliphatic or aliphatic polyamide, aromatic, aromatic/aliphatic or aliphatic polyimide, pbi, pbil, pan, pan-pvc copolymer, pan-methallyl sulfonate copolymer, pei, peek, sulfonated speek, ppo, poly-carbonate, polyester, ptfe, pvdf, pp, a polyelectrolyte complex, pmma, pdms, aromatic, aromatic/aliphatic or aliphatic polyimide urethane, aromatic, aromatic/aliphatic or aliphatic polyamidimide, crosslinked polyimide or poly-arylene ether, psu, ppsu and pesu, and b) at least one dope polymer dp1, which is a polyalkylene oxide with a molecular mass mw of more than 100,000 g/mol and/or a k-value of 60 or 20 more..
Basf Se

Fuel fractioning unit for inert gas generating system

An inert gas generating system includes a source of a liquid hydrocarbon fuel, and a fractioning unit configured to receive a portion of the liquid hydrocarbon fuel from the source. The fractioning unit includes a perm-selective membrane configured to separate the portion of the liquid hydrocarbon fuel into substantially sulfur-free vapors and a sulfur-containing remainder.
Hamilton Sundstrand Corporation

Combustion system for ships

A combustion system for ships operated at low cost is provided. A combustion system 1 for ships includes an internal combustion engine 20 that burns fuel, an exhaust line l2 through which exhaust gas flows, the exhaust gas being generated through combustion of the fuel in the internal combustion engine 20, an exhaust heat recovery device 40 that is disposed in the exhaust line l2 and that recovers exhaust heat from the exhaust gas discharged from the internal combustion engine 20, and a denitration device 50 that is disposed in the exhaust line l2 and that removes nitrogen oxide from the exhaust gas using a denitration catalyst.
Tokyo Metropolitan University

Waste gas treatment method with application of nano-bubble and waste gas treatment system using the same

A waste gas treatment method with the application of nano-bubbles and a waste gas treatment system using the same are provided. The method includes the steps of: feeding waste gas to an accommodating space; flowing a predetermined body of water in the accommodating space and generating the predetermined body of water including nano-bubbles; directing the waste gas mixed with the predetermined body of water including the nano-bubbles to a swirling unit; and discharging the treated gas waste.
Kunshan Nano New Material Technology Co., Ltd

Cyclic amine for selectively removing hydrogen sulphide

In which the r1 to r5 radicals are each as defined in the description, and an absorbent and a process for removing acidic gases from a fluid stream, especially for selectively removing hydrogen sulfide over carbon dioxide. The invention also relates to particular amines suitable for selective removal of hydrogen sulfide.

Amine compounds for selectively removing hydrogen sulphide

In which r1 to r8, x, y and z are as defined in the description. Also described is an absorbent comprising a solution of the compound, and the use thereof and a process for removing acid gases from a fluid stream, wherein the fluid stream is contacted with the absorbent.

Acid gas removal with an absorption liquid that separates in two liquid phases

An apparatus and method for acid gas removal using an absorption liquid comprising a chemical solvent and a non-chemical solvent, each absorbing acid gas, wherein in embodiments regeneration of the absorption liquid involves separating the two components from each other in separate streams, and causing desorption from each stream using different desorption conditions.. .
Nederlandse Organisatie Voor Toegepastnatuurwetenschappelijk Onderzoek Tno

Process for capturing co2 from a gas stream

The present invention relates to a process for capturing carbon dioxide from a gas stream. The gas stream is contacted with solid adsorbent particles in an adsorption zone.
Shell Oil Company

Wastesolution treatment systems

Wastesolution treatment systems and methods are provided which may remove particulates and hydrocarbons from wastesolution. Embodiments may be used to treat scrubber wastesolution from exhaust gas cleaning (“egc”) systems.
Ensolve Biosystems, Inc.

Modular interaction device for toys and other devices

A modular interaction device includes a wireless identification reading module to receive a unique identifier from a wireless identification tag attached with an object. The unique identifier may be sent to a server.
Amazon Technologies, Inc.

System and modeling the behavior of game elements during a remote game

Disclosed are systems and methods for modeling behavior of game elements during a remote game between at least two users. The system includes a positioning module configured to determine parameters for at least two game elements representing physical objects, and game manipulators that detect a physical action performed by a user in order to exert a force action on at least one game element and calculate one or more physical parameters characterizing the physical action.
Ao Kaspersky Lab

Information processing device, position and/or attitude estimiating method, and computer program

A first estimating unit estimates at least one of a position and an attitude of a predetermined object on the basis of an image of a periphery of the object, the image being obtained from an imaging device, and generates an estimation result not including an accumulated error. A second estimating unit estimates at least one of the position and the attitude of the object on the basis of the image, and generates an estimation result including an accumulated error.
Sony Interactive Entertainment Inc.

Exercise analyzing device, exercise analyzing system, and exercise analyzing method

An exercise analyzing device (a swing analyzing device) includes an acquiring section (a data acquiring section) configured to acquire an output of a first inertial sensor (an acceleration sensor and an angular velocity sensor) attached to a body of a user and an output of a second inertial sensor (an acceleration sensor and an angular velocity sensor) attached to an exercise instrument (a golf club), an analyzing section (a swing analyzing section) configured to analyze a correlation or a similarity degree between the output of the first inertial sensor and the output of the second inertial sensor and generate reference information, and an output processing section configured to estimate, when the second inertial sensor is not used, the output of the second inertial sensor from the output of the first inertial sensor and the reference information.. .
Seiko Epson Corporation

Exercise device

An exercise device for exercising at least one of a human hand, wrist, and forearm, may include a pair of handles that rotatably mounted within sockets by exerting a force that can be adjusted. Further, levers may be pivotably mounted relative to handles to facilitate developing grip strength.

Conveyor chain for a stepmill

A conveyor chain which is designed to be used on a stepmill to form into steps on the side interacting with a user, but which can fold into a generally flat configuration when returning to the top of the tread. Each step is designed to be formed of four generally identical segments where both the segments forming the tread and kickplate can fold relative to each other and each of the tread and kickplate can fold at a midpoint between two segments..
True Fitness Technology, Inc.

Exercise apparatus

An exercise device comprising: a frame having a generally vertical planar axis, first and second foot supports suspended on the frame by first and second linkage assemblies that are respectively arranged on the frame such that the first and second foot supports are pivotable through a front to back arcuate path of travel that is disposed at a selected angle between about five and about forty five degrees relative to the vertical planar axis.. .
Cybex International, Inc.

Exercise machine with multiple contact surfaces

An exercise machine with multiple contact surfaces for providing secondary exercise support platforms positioned at various planes relative to the horizontal plane of the primary exercising platforms, the secondary platforms further serving as handles used during the performance of exercises. The exercise machine with multiple contact surfaces generally includes a frame, a carriage movably attached to the rail, and a first support structure and a second support structure attached to the frame near the first end.
Lagree Technologies, Inc.

Brace with strap device for exercising stability muscles

Embodiments of the present invention are drawn to an exercise device generally having a strap, a brace, and a ring. The brace includes four finger straps and a thumb strap for looping around and gripping a user's fingers and thumbs, respectively.

Energy based fat reduction

Methods for non-invasive fat reduction can include targeting a region of interest below a surface of skin, which contains fat and delivering ultrasound energy to the region of interest. The ultrasound energy generates a thermal lesion with said ultrasound energy on a fat cell.
Guided Therapy Systems, Llc

System for monitoring the position of a patient receiving 4 pi radiation therapy

Disclosed is a method for determining a deviation of the position of an anatomical body part relative to a predetermined position defined by a radiation treatment plan. A monitoring image is taken of the anatomical body part at the instant that a predetermined control point defined in the treatment plan has been reached.
Brainlab Ag

Systems and methods for dose calculation in generating radiation treatment plans

A first dose calculated using a first set of fluence maps and a first (faster) dose prediction model is accessed. A second fluence map is accessed.
Varian Medical Systems International Ag.

Organic light-emitting device for light therapy for wound healing and cell proliferation and manufacturing method thereof

Disclosed is an organic light-emitting device for light therapy for wound healing and cell proliferation, including: a substrate; an organic light-emitting device layer formed on the substrate and emitting red light; and a heat sink layer formed on the organic light-emitting device layer, which forms a red organic light-emitting device emitting red light in a stacking structure including a heat sink layer to generate light in a form of a planar light source which can be driven at a low temperature, thereby solving a problem of a burn and can perform light therapy through close contact with the skin.. .
Seoul National University Bundang Hospital

Method and clinical effects-based targeting of neurostimulation

An example of a system for delivering neurostimulation may include a programming control circuit and a stimulation control circuit. The programming control circuit may be configured to generate stimulation parameters controlling delivery of the neurostimulation according to a stimulation configuration.
Boston Scientific Neuromodulation Corporation

External charger with adjustable alignment indicator

Electrical energy is transcutaneously transmitted at a plurality of different frequencies to an implanted medical device. The magnitude of the transmitted electrical energy respectively measured at the plurality of frequencies.
Boston Scientific Neuromodulation Corporation

Power generation for implantable devices

This application includes systems and techniques relating to wirelessly rechargeable medical apparatus, such as a wirelessly powered medical device including: a wireless energy harvesting module configured to receive at least one type of wireless power; a power management module configured to manage and monitor power harvested by the wireless energy harvesting module; a sensing or stimulation module configured to provide sensing data or a treatment operation; and a control module configured to communicate with the power management module and with the sensing or stimulation module; wherein the power management module and the control module are configured to communicate with each other to modify an interrelation of operations of the wireless energy harvesting module and the sensing or stimulation module, including to compensate for influences of wireless power harvesting on operation of the sensing module or on the treatment operation provided by the stimulation module.. .
Witricity Corporation

Microstimulator with rigid support structure

An implantable pulse generator (ipg) is disclosed herein. The ipg may be very small compared to most ipgs and may have a volume on the order of about 3 cm3.
Boston Scientific Neuromodulation Corporation

Methods and systems for generating a tissue pocket in a patient

Certain aspects of this disclosure relate to uniquely constructed medical implants that incorporate an electronic or other medical device. Some illustrative pocket-like implants provide an interior space for receipt of an electronic medical device, and are implantable in a patient with the electronic medical device positioned in the interior space.
Cook Medical Technologies Llc

Microstimulator having body-mounted electrodes and remote electrode leads

An implantable pulse generator (ipg) is disclosed herein. The ipg includes two or more body-mounted electrodes that can be independently programmed to provide stimulation at the location of implantation.
Boston Scientific Neuromodulation Corporation

Device and multi-modality spinal cord stimulation therapy

A device for neurostimulation includes a pulse generator for generating current having pulses and at least one first pair of electrodes connected to the pulse generator. The device provides a user-programmable therapy strength parameter configuration and at least two current parameter configurations for neurostimulation stored in the pulse generator.
Biotronik Se & Co. Kg

Targeted steerable transcranial intervention to accelerate memory consolidation

Described is a system to accelerate memory consolidation using a steerable transcranial intervention. During operation, the system generates a unique transcranial and steerable stimulation tag to associate with memory of a task or event.
Hrl Laboratories, Llc

Apparatus for electrically mediated delivery of therapeutic agents

Apparatus for the delivery of an electrical field which facilitates the intracellular delivery of a therapeutic agent to a predetermined site within the tissue of a patient. The apparatus will comprise a plurality of penetrating electrodes arranged in a predetermined spatial relationship, each electrode with a cross sectional area contributing to the total cross sectional area of all electrodes, and structural means incorporating an inanimate source of energy operatively connected to the plurality of electrodes for deploying the electrodes, wherein the source of energy is sufficient to impart a force of at least 1000 pounds per square inch (0.7 kilogram per square millimeter) of total cross sectional area of all electrodes at the initiation of the deployment of the electrodes.
Ichor Medical Systems, Inc.

Therapeutic agent injection device

A therapeutic agent injection device including an injection device for delivering a therapeutic agent to a patient having a body, the body having a patient face and a port face opposite the patient face, the port face having an introducer port including an introducer channel and an injection port including an injection channel, the introducer channel being in fluid communication with the injection channel through a cross channel, the injection channel defining an injection axis; a delivery tube for subcutaneous delivery of the therapeutic agent to the patient, the delivery tube projecting from and being generally perpendicular to the patient face, the delivery tube defining an introducer axis and being in fluid communication with the injection port; and a patch, the patch being attached to the patient face and being operable to adhesively attach to the patient; wherein the injection axis is parallel to the introducer axis.. .
Medtronic Minimed, Inc.

Continuous loop drainage system device and use

Disclosed is a continuous loop drainage system. The continuous loop drainage system uses a double-lumen catheter to augment drainage of a body fluid, such as bile or urine, in a prograde direction through a closed-loop system.
Board Of Regents, The University Of Texas System

Auxiliary small vasculature guidewire

The invention generally relates to an auxiliary guidewire for an intravascular procedure. The invention provides an auxiliary guidewire that slips over a primary guidewire and can provide a very fine extension beyond the end of the primary guidewire.
Volcano Corporation

Medical device securement system and method

A medical device securement system is configured to secure medical devices such as catheters in place. The securement system includes an anchor pad that attaches to a patient's skin.
Maddoc Medical Products, Inc.

Apparatus and maintaining airway patency and pressure support ventilation

An assembly for modifying airflow into a nasopharyngeal airway of a patient. A valve assembly is adapted to attach to an airflow generator.

Universal medical gas delivery system

A first source of medical gas has a generally cylindrical male outlet with a cylindrical bore and a threaded outer cylindrical surface. A flexible cylindrical elastomeric medical gas tubing has an input end with a bushing making a flush abutment with the male outlet at the output orifice.

Method and improved flow limitation detection of obstructive sleep apnea

In a respiratory apparatus for treatment of sleep apnea and other disorders associated with an obstruction of a patient's airway and which uses an airflow signal, an obstruction index is generated which detects the flattening of the inspiratory portion of the airflow. The flattening index serves as an obstruction index used to differentiate normal and obstructed breathing.
Resmed Limited

Aerosol delivery system

An aerosol delivery system is disclosed that is a single-use (disposable) continuous nebulizer system designed for use with mechanically ventilated patients to aerosolize medications for inhalation with a general purpose nebulizer, or for connection with devices usable in endoscopic procedures. The system separates the liquid reservoir from the nebulization process taking place either at the adapter hub, where it fits into an endotracheal tube (ett), or a gas humidifier, where the aerosol may treat a gas used in an endoscopic procedure, with a multi-lumen tube configured to nebulize liquid and air at its distal end.
Trudell Medical International

Aerosol delivery system and method

An aerosol delivery system that includes an aerosol generator that aerosolizes a fluid for delivery to a patient as a patient inhales. The aerosol delivery system includes a pump coupled to the aerosol generator that pumps the fluid to the aerosol generator, and a breath sensor that emits a signal as the patient breathes.
Stamford Devices Ltd.

Retrofit aerosol delivery system and method

An aerosol delivery system that includes an aerosol generator that aerosolizes a fluid for delivery to a patient as a patient inhales. The aerosol delivery system includes a pump coupled to the aerosol generator that pumps the fluid to the aerosol generator, and a breath sensor that emits a signal as the patient breathes.
Stamford Devices Ltd.

Aerosol delivery device

An aerosol delivery system that includes an aerosol generator that aerosolizes a fluid for delivery to a patient. The aerosol generator includes a housing with a fluid chamber that fluidly communicates with a housing inlet and a housing outlet.
Stamford Devices Ltd.

Antibacterial medical implant surface

Aspects include methods of fabricating antibacterial surfaces for medical implant devices including patterning a photoresist layer on a silicon substrate and etching the silicon to generate a plurality of nanopillars. Aspects also include removing the photoresist layer from the structure and coating the plurality of nanopillars with a biocompatible film.
International Business Machines Corporation

Antibacterial medical implant surface

Aspects include methods of fabricating antibacterial surfaces for medical implant devices including patterning a photoresist layer on a silicon substrate and etching the silicon to generate a plurality of nanopillars. Aspects also include removing the photoresist layer from the structure and coating the plurality of nanopillars with a biocompatible film.
International Business Machines Corporation

Antibacterial medical implant surface

Aspects include methods of fabricating antibacterial surfaces for medical implant devices including patterning a photoresist layer on a silicon substrate and etching the silicon to generate a plurality of nanopillars. Aspects also include removing the photoresist layer from the structure and coating the plurality of nanopillars with a biocompatible film.
International Business Machines Corporation

Antibacterial medical implant surface

Aspects include methods of fabricating antibacterial surfaces for medical implant devices including patterning a photoresist layer on a silicon substrate and etching the silicon to generate a plurality of nanopillars. Aspects also include removing the photoresist layer from the structure and coating the plurality of nanopillars with a biocompatible film.
International Business Machines Corporation

Polymeric mesh with selective permeability, for the repair and regeneration of tissues

Thus, the polymeric mesh for the repair and regeneration of tissues described in this application can be used in medicine in combination or not with surgical methods, namely in the treatment of diseases that involve the repair and regeneration of tissues, particularly when the tissue to treat is cartilage, periodontal ligament, esophagus or skin.. .

Devices for supporting regeneration of body tissues, and methods of making and using them

The invention provides devices for supporting regeneration of body tissue and of tubular structures, such as the esophagus or intestine, and methods for making and for using the devices.. .
Nanofiber Solutions, Inc.

Materials and methods for repair of cartilage defects

In one embodiment, the present invention includes a method for repairing a cartilage defect including: preparing a cartilage defect by removing unwanted or damaged tissue; creating at least one perforation into or through subchondral bone, below and/or adjacent to the cartilage defect to induce the flow of bone fluid; allowing the bone fluid to bleed through the at least one perforation up into the cartilage defect to fill at least a portion of the cartilage defect; and applying a biomaterial into the defect to produce a clot for cartilage regeneration.. .
Orthovita, Inc.

Bone substitute nanocomposites and methods of sythesis using multiphosphorylated peptides

The invention relates to peptides including dede(ssd)ndeg indicated by seq no. 1, rrrdede(ssd)ndeg indicated by seq no.
University Of Pittsburgh - Of The Commonwealth System Of Higher Education

Smart optic controller for a hydroxyl generator unit

A hydroxyl generator unit includes an ultraviolet light source, a reaction chamber within interior space of the hydroxyl generator unit, environmental sensors and a smart optic controller coupled to environmental sensors and to the ultraviolet light source. The smart optic controller integrates environmental conditions, and in response to at least the environmental conditions, the smart optic controller generates an output signal to the ultraviolet light source to control to the hydroxyls generated by the hydroxyl generator unit.
Hgi Industries, Inc.

Disinfectant dispenser for storing and delivering an agent for disinfecting surfaces and/or skin, disinfectant and publically signalling a disinfected state of persons

The invention relates to a disinfectant dispenser configured to store and dispense a surface and/or skin disinfectant, the disinfectant dispenser including a first storage container including a disinfectant; a second storage container (4) a including marking agent, wherein the marking agent is inactive in the second storage container; and a mixing section in which the marking agent is mixed with the disinfectant when the disinfectant dispenser is actuated, wherein the marking agent is provided in an inactive state after it is dispensed from the disinfectant dispenser. The disinfectant includes a disinfecting base component and a marking agent that is mixable with the base component, wherein the marking agent is inactive before it is mixed with the disinfecting base component and after mixing and applying the disinfectant to a surface the marking agent marks the disinfected surface through a coloration in a manner that is detectable by the human eye and also technically detectable, wherein the marking effect subsides with a subsiding disinfection state.

Room and area disinfection utilizing pulsed light with modulated power flux and light systems with visible light compensation between pulses

Disinfection methods and apparatuses are provided which generate pulses of germicidal light at a frequency greater than 20 hz and project the pulses of light to surfaces at least 1.0 meter from the disinfection apparatus. The pulses of light comprise a pulse duration and an energy flux sufficient to generate a power flux between approximately 200 w/m2 and approximately 5000 w/m2 of ultraviolet light in the wavelength range between 200 nm and 320 nm at the surfaces.
Xenex Disinfection Services, Llc.

Systems and apparratus for ultraviolet light disinfection

A disinfection system is provided herein. The disinfection system includes an uv light source to generate uv light and a housing supporting the uv light source.

Non-human primate model of age-related macular degeneration and producing same

An object of the present invention is to provide a method for producing a non-human primate model of amd, a method for evaluating the efficacy of a test substance in the prevention or treatment of amd using the amd animal model produced according to this method, and a method for screening substances effective in the prevention or treatment of amd using the aforementioned amd animal model. The method for preparing the amd animal model consists of administering sodium iodate into a vitreous body of a non-human primate, and the method for evaluating the efficacy of a test substance in the prevention or treatment of amd consists of preparing a non-human primate model of amd according to the aforementioned method for preparing an amd animal model, and evaluating the efficacy of the test substance in the prevention or treatment of amd using the resulting amd animal model..
Hamamatsu Pharma Research, Inc.

Diabetes gene therapy

There is described a nucleic acid molecule comprising a nucleotide sequence encoding for a functional preproinsulin protein wherein the nucleotide sequence has at least 86% identity to the sequence of seq id no. 1.
Ucl Business Plc

Anti-cancer and anti-inflammatory therapeutics and methods thereof

The invention relates to the discovery of a vital new component of the wnt pathway that regulates trafficking of β-catenin to the cell nucleus and novel therapeutic approaches to cancer treatment. Disclosed herein is a previously unknown, essential component of the wnt/β-catenin signaling pathway that governs the quantity of β-catenin delivered to the cell nucleus.
University Of Massachusetts

Homologous recombination in multipotent adult progenitor cells

The invention relates to methods of altering gene expression by homologous recombination in a multipotent adult progenitor cell (mapc). In particular, methods of producing a recombinant mapc, of correcting a genetic defect in a mammal, of providing a functional and/or therapeutic protein to a mammal, and of transforming a mapc are provided.
Regents Of The University Of Minnesota

Exon skipping oligomer conjugates for muscular dystrophy

Antisense oligomer conjugates complementary to a selected target site in the human dystrophin gene to induce exon 53 skipping are described.. .
Sarepta Therapeutics, Inc.

Neurotherapeutic nanoparticle compositions comprising leukemia inhibitory factor

There are provided compositions and methods for treatment of neurodegeneative diseases and cns injury. The compositions a pharmaceutically acceptable carrier solution; and a plurality of biodegradable nanoparticles, wherein the nanoparticles comprise a targeting moiety that is able to bind selectively to the surface of a neural stem cell and wherein the nanoparticles further comprise factors such as leukaemia inhibitory factor (lif); xav939 and/or one or more of: brain-derived neurotrophic factor (bdnf) or an agonist thereof; epidermal growth factor (egf) or an agonist thereof; glial cell-derived neurotrophic factor (gdnf) or an agonist thereof; retinoic acid and derivatives thereof; ciliary neurotrophic factor (ctnf) or an agonist thereof; and wnt5a.
Yale University

Methods for generating neutralizing anti-pathogen antibodies by directing the humoral response toward desired epitopes

Methods for generating antibodies to immuno-subdominant epitopes of elusive pathogens and vaccines and methods of vaccinating subjects against elusive pathogens are disclosed. The methods include targeting immunodominant b cells to undergo apoptosis, for example, while simultaneously targeting the germinal center (gc) reaction toward preferential selection and differentiation of b cells that produce broadly neutralizing antibody against a targeted pathogen..
Northeastern University

Herpes simplex virus type-1(hsv-1) vaccine strain vc2 generating an anti-ehv-1 immune response

The disclosure encompasses recombinant nucleic acids comprising a nucleotide sequence encoding a live-attenuated chimeric herpes simplex virus type-1 (hsv-1) vc2 virus and a nucleotide sequence encoding a heterologous polypeptide operably linked to a promoter. The nucleotide sequence encoding the heterologous polypeptide can be operably linked to a promoter encoding the glycoprotein d (gd) of equine herpesvirus-1 (ehv-1) or a fragment thereof.
Board Of Supervisors Of Louisiana State University And Agricultural And Mechan

Utilization of recombinant influenza viruses and modified vaccinia ankara virus (mva) with genes that encode for the toxoplasma gondii sag1 and sag2 surface proteins, as vaccines against toxoplasmosis

The present invention concerns to recombinant influenza viruses and modified vaccinia ankara viruses (mva), and to a process for construction of recombinant influenza viruses and modified vaccinia ankara viruses (mva) with genes that encode for the t. Gondii parasite sagi (mva) and sag2 (mva and influenza) proteins, by means of a homologous recombination technique between two transfer vectors (for construction of mva virus) and reverse genetics (for construction of influenza virus).
Fundacao Oswaldo Cruz

Compositions and methods for treatment of ocular diseases

Use of activated protein c (apc) for treatment and prevention of ocular diseases, disorders or conditions associated with retinal leakage and cnv such as age-related macular degeneration, optionally in combined therapy with anti-angiogenesis, anti-inflammatory, immunosuppressive, and anti pdgf agent.. .

Methods to treat ceroid lipofuscinosis using a recombinant adeno-associated virus

A method to prevent, inhibit or treat one or more symptoms associated with a disease of the central nervous system by intrathecally, intracerebroventricularly or endovascularly administering a raav encoding a gene product associated with the disease, e.g., a mammal in which the gene product is absent or present at a reduced level relative to a mammal without the disease.. .
Regenxbio Inc.

Methods to treat pompe disease using a recombinant adeno-associated virus

A method to prevent, inhibit or treat one or more symptoms associated with a disease of the central nervous system by intrathecally, intracerebroventricularly or endovascularly administering a raav encoding a gene product associated with the disease, e.g., a mammal in which the gene product is absent or present at a reduced level relative to a mammal without the disease.. .
Regenxbio Inc.

Adeno-associated virus mediated gene transfer to the central nervous system

A method to prevent, inhibit or treat one or more symptoms associated with a disease of the central nervous system by intrathecally, intracerebroventricularly or endovascularly administering a raav encoding a gene product associated with the disease, e.g., a mammal in which the gene product is absent or present at a reduced level relative to a mammal without the disease.. .
Regenxbio Inc.

Treating cancer with cas endonuclease complexes

The invention generally relates to compositions and methods for targeted delivery of a cas endonuclease or nucleic acid encoding a cas endonuclease to a fusion sequence in a cancer cell but not in a healthy cell of a subject. The cas endonuclease or nucleic acid encoding the cas endonuclease may be complexed with a guide rna complementary to a fusion sequence identified based on differences between a mutated sequence obtained from a cancer cell and a wild-type sequence obtained from a healthy cell of the subject.

Methods and products for nucleic acid production and delivery

The present invention relates in part to nucleic acids, including nucleic acids encoding proteins, therapeutics and cosmetics comprising nucleic acids, methods for delivering nucleic acids to cells, tissues, organs, and patients, methods for inducing cells to express proteins using nucleic acids, methods, kits and devices for transfecting, gene editing, and reprogramming cells, and cells, organisms, therapeutics, and cosmetics produced using these methods, kits, and devices. Methods and products for altering the dna sequence of a cell are described, as are methods and products for inducing cells to express proteins using synthetic rna molecules, including cells present in vivo.
Factor Bioscience Inc.

Use of full-length amelogenin for promoting nerve growth or regeneration

A method of promoting nerve growth or regeneration in a subject in need thereof, wherein the subject is not afflicted with a substantial connective tissue damage, is provided. The method comprises administering to the subject a therapeutically effective amount of full-length amelogenin, thereby promoting nerve growth or regeneration in the subject..
Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd.

Methods for modulating development and function of photoreceptor cells

The present invention relates to compositions and methods comprising administering gene modifiers for treating ocular disease.. .
The Schepens Eye Research Institute, Inc.

Genetic method to kill cancer cells by suffocation

A genetic method to kill cancer by suffocation is presented. The invention involves directly administering a bacterial plasmid in the form of an expression vector to cancer cells or tissue in a patient with cancerous growth.

Anti-androgen peptides and uses thereof in cancer therapy

The present invention relates to isolated or purified or partially purified peptide derived molecules having the following general formula (s1): x-[(pro)n-his-pro-his-ala-arg-ile-lys]m-y. The peptides are for medical use, in particular as anti-tumoral agents..
Cancer Research Technology Limited

Method for improving gingivitis and periodontitis by antibacterial, antioxidant and anti-inflammatory effects and inhibition of alveolar bone loss of complex extracts of moringa leaf and eucommia bark

The present invention relates to a method for preventing, improving or treating a periodontal disease, by administering a composition containing a moringa extract and a eucommia bark extract as active ingredients. More specifically, the complex composition of a moringa extract and a eucommia bark extract according to the present invention provides a synergistic effect in improvement of a periodontal disease including gingivitis and periodontitis.
Hlscience Co., Ltd.

Pharmaceutical compositions for promoting hair follicle regeneration and methods for preparing the same

Pharmaceutical compositions for promoting hair follicle regeneration and their respective preparation methods are provided to overcome the ineffectiveness and low efficiency of the conventional hair follicle regeneration techniques. The methods for preparing the pharmaceutical compositions for promoting hair follicle regeneration include seeding dermal papilla cells and adipocyte lineage cells on a culture material in order for the dermal papilla cells and the adipocyte lineage cells to jointly assemble cell spheres.
National Cheng Kung University Hospital

Spinal disc regenerative composition and manufacture and use

The present invention provides a novel way to replenish the disc using retooled disc compositions to repair degenerative discs. There is no better source of proteoglycans than the actual disc material (6) itself.
Vivex Biomedical, Inc.

Use of cart19 to deplete normal b cells to induce tolerance

The present invention provides compositions and methods for inducing tolerance in a human. The invention includes administering a genetically modified t cell expressing a car wherein the car comprises an antigen binding domain, a transmembrane domain, a costimulatory signaling region, and a cd3 zeta signaling domain..
The Trustees Of The University Of Pennsylvania

Selective treatment of prmt5 dependent cancer

The present invention generally relates to therapeutic inhibition of protein arginine methyltransferase 5 (prmt5). In particular, cell lines having mtap loss and increased intracellular mta concentrations show selective dependence on prmt5.
Dana-farber Cancer Institute, Inc.

Compositions and methods for parkinson's disease therapy

This disclosure provides methods for the treatment of one or more of: parkinson's disease (pd); pd symptoms; movement disorders; neurodegenerative diseases linked to changes in dopamine, dopamine signaling, or dopamine expression, in a subject in need thereof comprising administering to the subject an effective amount of an agent that potentiates dopaminergic neurotransmission. Also provided is a method for selecting a candidate agent for the treatment of parkinson's disease (pd); pd symptoms; and neurodegenerative diseases linked to changes in dopamine, dopamine signaling, or dopamine expression..

Methods for the separation and detection of an oxysterol

Assay methods for determining purity of a sample of a sterol are provided. These methods include providing an hplc eluent including a sterol, other compounds related to the sterol and a mobile volatile phase; generating an aerosol of liquid droplets from the hplc eluent; drying the liquid droplets to obtain residue particles of the sterol; contacting the residue particles of the sterol with an ion stream which applies a size-dependent electrical charge to each of the residue particles to generate an electrical signal and measuring the electrical signal to determine the purity of the sterol in the sample.
Warsaw Orthopedic, Inc.

No-rinse chemical foam containing clobetasol propionate, and use thereof in the treatment of psoriasis

A self-foaming composition is described that includes clobetasol propionate, for a no-rinse topical application and for application to the skin. The composition can include: at least one intermediate composition b including a gas-generating agent; at least one intermediate composition a including an agent for activating the gas-generating agent; and clobetasol propionate being present in at least one of the intermediate compositions a and b.
Galderma Research & Development

Prostamide-containing intraocular implants and methods of use thereof

Prostamide-containing intraocular implants that biodegrade in the eye and that are effective for reducing intraocular pressure in an eye for a sustained period. The implants generally contain a prostamide, such as bimatoprost, and at least three distinct biodegradable polymers selected from polylactide and poly(lactide-co-glycolide) polymers and are optimized for placement in and compatibility with the anterior chamber of the eye, particularly the anterior chamber angle.
Allergan, Inc.

Bumped kinase inhibitor compositions and methods for treating cancer

The present disclosure is generally directed to bumped kinase inhibitor (bki) compositions and methods for treating cancer.. .
University Of Washington

Treatment of anxiety disorders and autism spectrum disorders

Disclosed are methods for treating autism spectrum disorders and/or anxiety disorders by administering certain nr2b subunit-selective nmda (n methyl-d aspartate) antagonists. Anxiety disorders include agoraphobia (with or without panic disorder), generalized anxiety disorder (gad), social anxiety disorder (sad), panic disorder (pd), post-traumatic stress disorder (ptsd) and obsessive-compulsive disorder (ocd)..
Rugen Holdings (cayman) Limited

Compositions and methods for white to beige adipogenesis

Disclosed herein are compositions and methods for transitioning or converting a white adipocyte to a beige adipocyte. The compositions and methods may be used in the treatment of obesity.

Aldose reductase inhibitors and uses thereof

The present invention relates to novel compounds and pharmaceutical compositions thereof, and methods for promoting healthy aging of skin, the treatment of skin disorders, the treatment of cardiovascular disorders, the treatment of renal disorders, the treatment of angiogenesis disorders, such as cancer, treatment of tissue damage, such as non-cardiac tissue damage, the treatment of evolving myocardial infarction, and the treatment of various other disorders, such as complications arising from diabetes with the compounds and compositions of the invention. Other disorders can include, but are not limited to, atherosclerosis, coronary artery disease, diabetic nephropathy, diabetic neuropathy, diabetic retinopathy, infections of the skin, peripheral vascular disease, stroke, and the like..
The Trustee Of Columbia University In The City Of New York

Treatment of cancer by inhibiting ezh2 activity

The invention relates to inhibitors of ezh2 for use in the treatment of cancers characterised by expression of mutated histone h3 having a mutation of amino acid number 27. The invention also relates to methods for predicting the efficacy of treatment of a cancer with an inhibitor of ezh2 by determining whether the cancer cells contain a gene encoding p16ink4a, wherein the presence of a gene encoding p16ink4a is indicative of efficacy of treatment of the cancer with an inhibitor of ezh2..
University Of Copenhagen

Histone deacetylase (hdac) inhibitors for the treatment of cancer

The present invention relates generally to methods for treating cancer. In one respect, the present invention relates to a method of treating a hematological cancer (e.g., multiple myeloma, leukemia, lymphoma) comprising administering to a patient in need thereof a therapeutically affective amount of a histone deacetylase inhibitor, for