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Bronchi

Bronchi-related patent applications - as published by the U.S. Patent and Trademark Office (USPTO).


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Composition for use in treating and preventing inflammation related disorder
Aihol Corporation
August 09, 2018 - N°20180221492

The present invention is related to a use for treating and preventing inflammation related disorder of a composition containing a drug and hyaluronic acid (ha) or ha mixture, whereas the ha or the ha mixture as a delivery vehicle can be a formulation including at least two has having different average molecular weights. The composition has been demonstrated to be ...
Live attenuated arkansas serotype infectious bronchitis virus vaccine
University Of Georgia Research Foundation, Inc.
August 02, 2018 - N°20180216082

Attenuated isolates of the arkansas serotype of infectious bronchitis virus (ibv), including the ibv isolate arkga p60 deposited at the atcc under patent designation pta-123783, and compositions thereof are presented. Methods for administering the isolates or compositions as vaccines to the prevent virulent ibv infection in birds of the order galliformes also presented..
Compound having ep2 agonist activity
August 02, 2018 - N°20180215747

(wherein all symbols are as defined in the description), a salt or n-oxide of the compound, or a solvate or prodrug of the compound or the salt or n-oxide has an ep2 agonist activity and is highly safe, and is therefore useful as a medicine, particularly a therapeutic agent for diseases associated with ep2 receptors, such as immune diseases, allergic ...
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Touch-sensitive user interface intended for a tracheobronchial-air stimulation device
July 26, 2018 - N°20180207380

Disclosed is a touch-sensitive user interface intended to interact with a tracheobronchial-air stimulation device including: —a touch-sensitive display screen for providing the user with information about the use of the tracheobronchial-air stimulation device, —a communication module for communicating data between the touch-sensitive user interface and the tracheobronchial-air stimulation device, —a memory in which biofeedback software and data, ...
Device for stimulating tracheobronchial air
July 19, 2018 - N°20180200462

Disclosed is a device for stimulating the tracheobronchial air of a patient suffering from an obstructive ventilatory disorder and able to modify the rheology of his tracheobronchial mucus, which includes a negative pressure generator, a physiological interface able to interface the device with the patient's respiratory apparatus, a connection pipe connecting the physiological interface to the negative pressure generator, and ...
In vitro epithelial models comprising lamina propria-derived cells
Emulate, Inc.
July 05, 2018 - N°20180185844

An in vitro microfluidic “organ-on-chip” is described herein that mimics the structure and at least one function of specific areas of the epithelial system in vivo. In particular, a multicellular, layered, microfluidic culture is described, allowing for interactions between lamina propria-derived cells and the associated tissue specific epithelial cells and endothelial cells.
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Bicyclic heteroaryl derivatives as cftr potentiators
Cystic Fibrosis Foundation Therapeutics, Inc.
June 21, 2018 - N°20180170938

The present invention relates to 1,3-disubstituted-1h-pyrazolo[3,4-d]pyrimidin-4-amine derivatives, 5,7-disubstituted-pyrrolo[2,1-f][1,2,4]triazin-4-amine derivatives or 5,7-disubstituted-imidazo[5,1-f][1,2,4]triazine-4-amine derivatives, and pharmaceutically acceptable salts thereof. The compounds are potentiators of cystic fibrosis transmembrane conductance regulator (cftr).
Methods and products for treating and/or delaying onset of dysplastic lesions
Aktiv-dry Llc
June 14, 2018 - N°20180161283

Methods for treating and/or delaying onset of dysplastic lesions in the bronchial airway of an individual comprise delivering to the respiratory track of the individual an inhalable dry powder composition including an effective amount of myo-inositol.. .
Systems and methods for sympathetic cardiopulmonary neuromodulation
Reflex Medical, Inc.
May 31, 2018 - N°20180147260

Methods, devices and systems are described for decreasing the activity of the sympathetic nervous innervation to and from the lungs and the vessels supplying the lungs to treat pulmonary medical conditions such as asthma. In one embodiment, the method may involve advancing an intravascular instrument to a target location in a blood vessel within the intercostal vasculature to ablate either ...
3-(phenyl)-n-(4-phenoxybenzyl)-1,2,4-oxadiazole-5-carboxamide compounds for the management of cftr protein mediated ...
Emory University
May 31, 2018 - N°20180147190

This disclosure relates to methods of treating or preventing cystic fibrosis transmembrane conductance regulator (cftr) mediated diseases such as cystic fibrosis, chronic obstructive pulmonary disease, chronic pancreatitis, chronic bronchitis, asthma, mucus formation, comprising administering an effective amount of a 3-(phenyl)-n-(4-phenoxybenzyl)-1,2,4-oxa-diazole-5-carboxamide compound, salt, or derivative thereof to a subject in need thereof. In certain embodiments, ...
Compounds, compositions, and methods for increasing cftr activity
Proteostasis Therapeutics, Inc.
May 31, 2018 - N°20180147187

The present disclosure features compounds such as those having the formulae (iia), (iib), (iic), (iid), (iiia), and (iiib), which can increase cystic fibrosis transmembrane conductance regulator (cftr) activity as measured in human bronchial epithelial (hbe) cells. The present disclosure also features methods of treating a condition associated with decreased cftr activity or a condition associated with a dysfunction of proteostasis ...
2-amino-n'-benzylideneacetohydrazides and derivatives for the management of cftr protein mediated diseases
Bar-ilan University
May 31, 2018 - N°20180147164

This disclosure relates to methods of treating or preventing cystic fibrosis transmembrane conductance regulator (cftr) mediated diseases such as cystic fibrosis, chronic obstructive pulmonary disease, chronic pancreatitis, chronic bronchitis, asthma, mucus formation, comprising administering an effective amount of a 2-amino-n′-benzylidene-acetohydrazide compound or derivative thereof to a subject in need thereof. In certain embodiments, the 2-amino-n-benzylidene-acetohydrazide compound is ((e)...
Pyrrolopyrimidines as cftr potentiators
May 24, 2018 - N°20180141954

Wherein r1a, r1b, r2, r3, r4, w, y, and z are as described herein, and pharmaceutically acceptable salts thereof. The compounds are potentiators of cystic fibrosis transmembrane conductance regulator (cftr).
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System and method for bronchial dilation
Nuvaira, Inc.
May 17, 2018 - N°20180133475

A method of reducing bronchial constriction in a subject includes delivering energy to create one or more lesions on a main bronchus so as to transect pulmonary nerves sufficiently to reduce bronchial constriction in a lung of the patient distal to the main bronchus.. .
Immunogenic and vaccine compositions for use against bordetella bronchiseptica infection
Cyanimal Ip
May 17, 2018 - N°20180133301

The present invention in certain embodiments generally relates to an immunogenic composition comprising bordetella sp. Adenylate cyclase toxin (cyaa) for use in treating bordetella bronchiseptica infections in non-human animals.
Solanum dubium seeds and honey (extracted from bee hives in acacia tree populated area) combination ...
May 17, 2018 - N°20180133264

As a clinical trial for the combined ingredients, twenty five patients medically diagnosed as asthmatic were randomly selected and enrolled in the study; none of them is currently using anti-asthmatic drugs. Signs of asthma disappeared in the treated patients..
Lung volume-reducing elastic implant and instrument
Lifetech Scientific (shenzhen) Co., Ltd.
May 17, 2018 - N°20180132860

A lung volume-reducing elastic implant (2) and a lung volume-reducing instrument; the lung volume-reducing elastic implant (2) is tubular and comprises a proximal implant end (201), an elastic deformation part (205) and a distal implant end (202); the elastic deformation part (205) is located between the proximal implant end (201) and the distal implant end (202), and the elastic deformation part (205) has a shape memory characteristic; the lung ...
Pharmaceutical composition comprising glutarimide derivatives and use thereof in the treatment of eosinophilic diseases
Obschestvo S Ogranichennoi Otvetstvennostiyu "pharmenterprises"
April 19, 2018 - N°20180104230

The present invention relates to novel biologically active glutarimide derivatives of general formula (i) or a pharmaceutically acceptable salt thereof, their use as a therapeutic agent for the treatment of eosinophilic diseases, preferably of allergic nature, in particular bronchial asthma, allergic rhinitis, polypous rhinosinusopathies, eosinophilic colitis, eosinophilic syndrome, allergic conjunctivitis, atopic dermatitis, churg-strauss syndrome, anaphylactic shock, quincke's edema, eosinophilic vasculitis, ...
Compound for treating respiratory syncytial virus infection and preparation method and use thereof
Shandong University
April 05, 2018 - N°20180094021

The present invention declares a kind of compound to treat respiratory syncytial virus infection and its preparation method and application. The compound stated is cyclopamine's chemical analogs, has the property of inhibiting respiratory syncytial virus replication, and does not have the property of inhibiting hedgehog signaling pathways.
Medical tubes for selective mechanical ventilation of the lungs
April 05, 2018 - N°20180093058

A single lumen endobronchial tube for selective mechanical ventilation of the lungs can include a medical tube having a single lumen with an opening at each of opposed distal and proximal ends of the tube, the opening at the proximal end of the tube being adapted for connection to an external mechanical ventilation device, and the opening at the distal ...
Pyrazolothiazole compound and medicine comprising same
April 05, 2018 - N°20180092919

The compound of the invention has jak1 inhibitory activity, and thus, immunosuppressive effect, anti-inflammatory effect and anti-proliferative effect, and is useful in the treatment of the diseases, for example, rheumatoid arthritis, inflammatory bowel disease, psoriasis and vasculitis, bronchial asthma, chronic obstructive pulmonary disease and eosinophilic sinusitis, nasal polyp.. .
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