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Wound Healing patents



      
           
This page is updated frequently with new Wound Healing-related patents. Subscribe to the Wound Healing RSS feed to automatically get the update: related Wound RSS feeds.

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Date/App# patent app List of recent Wound Healing-related patents
04/17/14
20140107682
 Dissection handpiece and method for reducing the appearance of cellulite patent thumbnailDissection handpiece and method for reducing the appearance of cellulite
A dermatological skin treatment device is provided. The device comprises a handpiece and a cutting tool, wherein the tool is inserted through the conduit and percutaneously inserted into a tissue disposed within a recessed area of the handpiece.
04/17/14
20140107600
 Reduced-pressure wound dressings and systems for re-epithelialization and granulation patent thumbnailReduced-pressure wound dressings and systems for re-epithelialization and granulation
Methods for promoting re-epithelialization and granulation as an aspect of wound healing are presented. A method for promoting granulation and re-epithelialization of a wound at the same time involves using a reduced-pressure treatment dressing and applying a moist, water-sensitive barrier to promote re-epithelialization and to inhibit granulation.
04/17/14
20140107025
 Ocular drug delivery system patent thumbnailOcular drug delivery system
An ocular drug delivery system including a composition in which a formulation having an active agent such as rhgh and or an rhgh mimic, e.g., that increases insulin growth factor (igf) or that alters insulin growth factor binding protein (igfbp) in a subject is dispersed in a pharmaceutical carrier. The composition is configured for placement in, around or on an eye of the subject, and the composition provides controlled release of an amount of the active agent to the eye effective to promote ocular surface and corneal neural regeneration and wound healing..
04/03/14
20140094502
 Rnai inhibition of ctgf for treatment of ocular disorders patent thumbnailRnai inhibition of ctgf for treatment of ocular disorders
Rna interference is provided for inhibition of connective tissue growth factor mrna expression in ocular disorders involving ctgf expression. Ocular disorders involving aberrant ctgf expression include glaucoma, macular degeneration, diabetic retinopathy, choroidal neovascularization, proliferative vitreoretinopathy and wound healing.
04/03/14
20140094467
 Method and composition for modulating canonical wnt pathway using folate and inositol patent thumbnailMethod and composition for modulating canonical wnt pathway using folate and inositol
The canonical wnt signaling pathway is implicated in many disorders including neural tube defects, limb malformations, and heart defects, developmental disorders associated with alcohol exposure (fetal alcohol syndrome) or exposure to bipolar medications (i.e. Lithium), wound healing, and alzheimer's disease.
04/03/14
20140094413
 Hepatocyte growth factor (hgf) mimics as therapeutic agents patent thumbnailHepatocyte growth factor (hgf) mimics as therapeutic agents
Small molecule, peptidic hepatocyte growth factors mimics, which act as both mimetics and antagonists, have been generated. These molecules have been shown or predicted to have therapeutic potential for numerous pathologies including dementia, alzheimer's disease, parkinson's disease, amyotrphic lateral sclerosis, and other neurodegenerative diseases, spinal cord injury, traumatic brain injury, diabetes and metabolic syndrome, cancer, and defective wound healing..
04/03/14
20140093593
 Decubitus treatment system patent thumbnailDecubitus treatment system
The present invention includes compositions and methods for cleaning, treating, protection and resolution of decubitus ulcers comprising: a first composition comprising a wound cleaning solution comprising aloe vera gel comprising at least 5,000 mps, a balanced salt solution; and a second composition comprising a wound healing gel comprising aloe vera gel comprising at least 10,000 mps, a thickening agent, and one or more preservatives and, optionally, a third composition comprising a moisture barrier cream comprising a vegetable-based emulsifier, a cosmetic ester for dry skin that has low occlusivity, an ester-based emollient that is oxidation stable and has low occlusivity; a beeswax; a hydrogenated oil, glycerin, a buffering agent, aloe vera gel comprising at least 2,000 mps and water.. .
03/27/14
20140088563
 Method of deriving stem cells, stem cells, and use of stem cells for wound healing patent thumbnailMethod of deriving stem cells, stem cells, and use of stem cells for wound healing
A method of deriving isolated stem cells including: implanting a matrix in a wound site of a living organism; allowing cells to infiltrate the matrix; removing the matrix containing the infiltrated cells from the wound site; and removing the infiltrated cells from the matrix to provide isolated stem cells. Stem cells produced by this process, stem cells with certain characteristics, and methods for treating wounds using these stem cells are provided..
03/27/14
20140088489
 Wound care apparatus patent thumbnailWound care apparatus
The invention is applicable to the field of medical care products, and provides a wound care apparatus. The wound care apparatus comprises a pump and a sealed dressing connected to the pump via a first pipeline, a laser being disposed at the upper end of the sealed dressing.
03/27/14
20140088481
 Controlled strain skin treatment devices and methods patent thumbnailControlled strain skin treatment devices and methods
Devices, kits and methods described herein may be for wound healing, including but not limited to the treatment, amelioration, or prevention of scars and/or keloids. The packaging, manipulation elements, applicator and/or tensioning device maybe used to apply and/or maintain a strain in an elastic dressing..
03/27/14
20140088004
Hepatocyte growth factor mimics as therapeutic agents
Small molecule, peptidic hepatocyte growth factors mimics, which act as both mimetics and antagonists, have been generated. These molecules have been shown or predicted to have therapeutic potential for numerous pathologies including dementia, neurodegenerative disease, diabetes and metabolic syndrome, cancer, and defective wound healing..
03/27/14
20140086963
Methods of wound care and treatment
Particular embodiments disclosed herein relate to gas-enriched fluids, methods of making the same, systems for making the same and/or methods of treatment utilizing the gas-enriched fluids for wound care related conditions and/or diseases. In certain embodiments, the gas-enriched fluid is oxygen-enriched water.
03/27/14
20140086886
Stem cell, precursor cell, or target cell-based treatment of multi-organ failure and renal dysfunction
Methods for the treatment of acute renal failure, multi-organ failure, early dysfunction of kidney transplant, chronic renal failure, organ dysfunction, and wound healing are provided. The methods include delivering a therapeutic amount of hematopoietic stem cells, non-hematopoietic, mesenchymal stem cells, hemangioblasts, and pre-differentiated cells to a patient in need thereof..
03/20/14
20140081192
Primary dressing for moist wound healing, and method for producing said primary dressing
The invention relates to a primary dressing for moist wound healing with a reduced risk of inflammation. The elastic primary dressing according to the invention for moist wound healing is in the form of a lattice or a netting made of elongated elastic bodies, said lattice or netting containing non-resorbable elongated bodies that consist of silicone and optionally at least one additive selected from active pharmacological ingredients, collagens, hydrocolloids, and/or dyes.
03/20/14
20140080902
B- and y -diketones and y -hydroxyketones as wnt/ b -catenin signaling pathway activators
The present invention discloses β-diketones, γ-diketones or γ-hydroxyketones or analogs thereof, that activate wnt/β-catenin signaling and thus treat or prevent diseases related to signal transduction, such as osteoporosis and osteoarthropathy; osteogenesis imperfecta, bone defects, bone fractures, periodontal disease, otosclerosis, wound healing, craniofacial defects, oncolytic bone disease, traumatic brain injuries related to the differentiation and development of the central nervous system, comprising parkinson's disease, strokes, ischemic cerebral disease, epilepsy, alzheimer's disease, depression, bipolar disorder, schizophrenia; eye diseases such as age related macular degeneration, diabetic macular edema or retinitis pigmentosa and diseases related to differentiation and growth of stem cell, comprising hair loss, hematopoiesis related diseases and tissue regeneration related diseases.. .
03/20/14
20140080759
Compositions comprising multivalent synthetic ligands of surface nucleolin and glycosaminoglycans
The present invention relates to a composition comprising a nucant multivalent synthetic compound and a glycosaminoglycan, the admixture of both compounds forming microspheres comprising both compounds, as well as their use for the treatment or prevention of diseases associated with deregulation of proliferation and/or angiogenesis, such as cancer, inflammatory disease, or for promoting wound healing.. .
03/20/14
20140079737
Use of immunomodulatory protein in promotion of wound healing or treatment of tissue injury
The invention provides a method for promoting wound healing or tissue injury treatment in a subject in need thereof, the method comprising administering to the subject an effective amount of one or more fungal immunomodulatory protein (preferably, ganoderma immunomodulatory protein).. .
03/06/14
20140067058
Reinforced placental tissue grafts and methods of making and using the same
Described herein are tissue grafts derived from the placental tissue that are reinforced with at least one biocompatible mesh. The tissue grafts possess good adhesion to biological tissues and are useful in wound healing applications.
03/06/14
20140066786
Method and apparatus for improved wound healing and enhancement of rehabilitation
Methods and a device for improving wound healing and for improving the effects of rehabilitative therapies in patients with cognitive and motor deficits are provided. Repeated regimens of remote ischemic conditioning are performed.
03/06/14
20140065121
Blood plasma based hydrogels for tissue regeneration and wound healing applications
The present disclosure generally relates to tissue engineering and wound healing. More particularly, the present disclosure relates to the modification of plasma with a stability conferring agent to create a hydrogel for use in regenerative medicine and other tissue engineering applications..
03/06/14
20140065109
Use of substance p for mobilization of mesenchymal stem cells or proliferation of mesenchymal stem cells and for wound healing or facilitating wound healing
The present invention relates to a use of substance-p for the manufacture of a medicament for mobilization or proliferation of mesenchymal stem cells (mscs) from the bone marrow, or facilitating said mobilization or proliferation, and use of substance-p for the manufacture of a medicament for wound-healing or facilitating wound-healing.. .
03/06/14
20140065106
Blood plasma based hydrogels for tissue regeneration and wound healing applications
The present disclosure generally relates to tissue engineering and wound healing. More particularly, the present disclosure relates to the modification of plasma with a stability conferring agent to create a hydrogel for use in regenerative medicine and other tissue engineering applications..
02/27/14
20140058117
Process for the synthesis of substituted gamma lactams
The present invention provides synthetic processes for the preparation of a variety of well-defined substituted gamma lactams. The compounds that can be prepared by the process of the invention are useful for treating a variety of conditions.
02/27/14
20140057955
Novel, protective, anti-inflammatory receptor and its use in preservation of mitochondrial function, wound healing and repair
Provided herein is a novel mitochondrial angiotensin ii type 1 and type 2 at1r and at2r receptor which plays a role in protection of mitochondria against oxidative damage. Evidence from animal studies indicates a role for this receptor in preservation of mitochondria and up-regulation of survival genes, anti-inflammatory action, and improvement of wound healing in the skin and soft tissues.
02/27/14
20140057311
Device for high throughput investigations of multi-cellular interactions
Provided herein are microfluidic devices that can be used as a 3d bioassay, e.g., for drug screening, personalized medicine, tissue engineering, wound healing, and other applications. The device has a series of channels {e.g., small fluid channels) in a small polymer block wherein one or more of the channels can be filled with a biologically relevant gel, such as collagen, which is held in place by posts.
02/27/14
20140056964
Granzyme b inhibitor compositions, methods and uses for promoting wound healing
Methods of promoting wound healing in a subject is disclosed. The method include applying a granzyme b (granzyme b) inhibitor to the wound.
02/20/14
20140052216
Methods for promoting wound healing
A method for promoting wound healing at a wound site includes subjecting the wound site to electrical pulses to promote wound healing during at least one of the stages of wound healing. The method may further include closing the wound site by sutures or staples prior to and or after applying the electrical pulses that promote wound healing..
02/13/14
20140046348
Wound healing system
A novel system for securing a material to tissue is disclosed. The system may include a body and a plurality of engagement members extending from the body.
02/06/14
20140038938
Substituted dihydropyrazolones and their use
The present application relates to novel substituted dihydropyrazolone derivatives, processes for their preparation, their use for treatment and/or prophylaxis of diseases and their use for the preparation of medicaments for treatment and/or prophylaxis of diseases, in particular cardiovascular and haematological diseases and kidney diseases, and for promoting wound healing.. .
02/06/14
20140038880
Compositions and methods for promoting wound healing and tissue regeneration
Provided herein are compositions and methods for use in promoting wound healing and tissue regeneration following tissue injury in a subject.. .
02/06/14
20140037711
Pendant hydrophile bearing biodegraadable compositions and related devices
The present invention provides a method of wound healing, comprising administering the composition or patch.. .
02/06/14
20140037601
Nutritional compositions including branched chain fatty acids for wound healing
Nutritional compositions for improving, treating and/or preventing various medical conditions and methods of using same are provided. The medical conditions may include wounds, mucositis among others.
01/30/14
20140031774
Assemblies, systems, and methods for vacuum assisted internal drainage during wound healing
Assemblies, systems, and methods convey fluid from an internal wound site or body cavity by applying negative pressure from a source outside the internal wound site or body cavity through a wound drain assembly that is placed directly inside the internal wound site or body cavity.. .
01/30/14
20140031329
Substituted dihydropyrazolones for treating cardiovascular and hematological diseases
The present application relates to novel substituted dihydropyrazolone derivatives, processes for their preparation, their use for treatment and/or prophylaxis of diseases and their use for the preparation of medicaments for treatment and/or prophylaxis of diseases, in particular cardiovascular and hematological diseases and kidney diseases, and for promoting wound healing.. .
01/30/14
20140030233
Therapeutic compositions and methods
This invention relates the use of cortisol blockers (glucocorticoid receptor [gr] antagonists) for the prevention or addiction induced anxiety and withdrawal side effects as a therapeutic and in concert with a diagnostic. Such addictions could be, but are not limited to, alcohol, drugs, caffeine, sugar, food, nicotine, etc.
01/23/14
20140023610
Silicone gel-based compositions for wound healing and scar reduction
This invention is a composition comprising a cyclic siloxane, a silicone occlusive fluid, a silicone occlusive gel, and a silicone resin powder. The composition is useful for wound healing..
01/16/14
20140018434
Cleaning, insecticide, insect repellant, glue solvent and anti-irritation composition
Exemplary embodiments of the present invention relate to pesticides, insecticides, insect repellant, insect anti-feeding, cleaning, glue dissolving and anti-irritation and wound healing compositions for humans and animals and, more particularly, to such compositions which are effective in killing, removing and/or repelling a wide range of endoparasites, ectoparasites and insects while also being non-toxic to humans, animals, and the environment. An exemplary embodiment of the present invention is directed to an aqueous composition including a mixture of at least one ethanolamide and at least one esterified fatty acid.
01/02/14
20140005228
B- and y -diketones and y -hydroxyketones as wnt/ b -catenin signaling pathway activators
The present invention discloses β-diketones, γ-diketones or γ-hydroxyketones or analogs thereof, that activate wnt/β-catenin signaling and thus treat or prevent diseases related to signal transduction, such as osteoporosis and osteoarthropathy; osteogenesis imperfecta, bone defects, bone fractures, periodontal disease, otosclerosis, wound healing, craniofacial defects, oncolytic bone disease, traumatic brain injuries related to the differentiation and development of the central nervous system, comprising parkinson's disease, strokes, ischemic cerebral disease, epilepsy, alzheimer's disease, depression, bipolar disorder, schizophrenia; eye diseases such as age related macular degeneration, diabetic macular edema or retinitis pigmentosa and diseases related to differentiation and growth of stem cell, comprising hair loss, hematopoiesis related diseases and tissue regeneration related diseases.. .
01/02/14
20140004546
Colorimetric gelatinase assay
The present invention is drawn toward a lateral-flow, colorimetric, gelatinase assay including a sample pad, a reagent pad, a membrane, and an absorbent pad, in that order, wherein the reagent pad has therein a dried form of gelatin-coated nanoparticles in a salt and sugar matrix, and wherein the membrane portion has a test stripe and a control stripe, such that the test stripe is a solution of electrolyte evaporated into a layer, and the control stripe is a solution of anti-gelatin antibody evaporated into a layer. The present invention is also drawn toward a method of detecting one or more gelatinases in a sample fluid using the assay, and methods of determining treatment for wound healing, cancer, ocular rosacea, periodontal disease and equine arthritis using the assay..
01/02/14
20140004091
Activated leukocyte composition and uses for wound healing
Disclosed are therapeutic, blood-derived activated leukocyte compositions, methods of making them, and methods of using the compositions to repair or promote the prevention and healing of wounds.. .
12/19/13
20130338160
Compounds with (1e, 6e)-1,7-bis-(3,4-dimethoxyphenyl)-4,4-disubstituted-hepta-1,6-diene-3,5-dione structural scaffold, their biological activity, and uses thereof
The present invention includes compounds, pharmaceuticals and cosmetics having at least one (substituted phenyl)-propenal moiety. The compounds and compositions of the present invention are useful in the treatment or prevention of medical conditions including androgen associated conditions, androgen associated inflammation, a wound (the compounds assist with wound healing), acne, rheumatoid arthritis, psoriasis, rosacea, and alopecia; kennedy's disease (spinal and bulbar muscular atrophy, or sbma), polyglutamine-mediated motor neuron degeneration; cancers such as prostate cancer, bladder cancer, breast cancer, ovarian cancer, hepatocellular (liver) cancer, and pancreatic cancer; and other medical conditions described herein.
12/19/13
20130338158
6-substituted indole-3-carboxylic acid amide compounds having sphingosine-1-phosphate (s1p) receptor antagonist biological activity
And wherein the variables y, r4, n, o, a, a1, a2, x, z, r1, r3, r2, p, q and r are as defined in the specification. These compounds are useful for treating a disease or condition selected from the group consisting of glaucoma, dry eye, angiogenesis, cardiovascular conditions and diseases, and wound healing.
12/19/13
20130338073
Durable haemostatic scaffold
A haemostatic and adhesive durable scaffold useful for promoting wound healing is provided. A scaffold made of fibrinogen and chitosan is produced by electrospinning techniques, resulting in a material with enhanced endurance, applicable in various medical purposes including surgery, tissue regeneration, burns, injuries, etc.
12/19/13
20130337038
Chimeric fibronectin matrix mimetics and uses thereof
The present invention is directed to recombinant fibronectin peptide mimetics and wound healing compositions containing the same. Other aspects of the present invention include wound healing dressings that comprise the wound healing composition of the present invention and a wound dressing material and methods of treating wounds using these compositions..
12/19/13
20130336899
Antimicrobial formulations that aid in wound healing
The invention discloses compositions and formulations for the treatment of clean or infected wounds, some of the inventive formulations can be used to reduce or eliminate microbial contamination from surfaces such as skin, and inanimate objects such as countertops, cooking utensils, medical devices, cookware, food, grooming aids and agricultural biocides, and the like. Some of these compositions and formulations are well suited for use in wound dressings.
12/12/13
20130330397
Wound care products with peracid compositions
Methods have been developed for incorporation of a peracid compound into or on wound application matrices, such as bandages or dressings, and other matrices which will favorably impact wound healing and help eliminate microbial infection. The peracid compound comprises a base compound that is metabolically pertinent to wound healing, the oxidized form of the base compound (a peracid), and an appropriate oxidizer, such as hydrogen peroxide.
12/05/13
20130323337
Novel herbal composition for the treatment of wound healing, a regenerative medicine
The present invention discloses a novel, synergistic, effective herbal composition as a regenerative medicine comprising combination therapeutically effective amounts of extracts obtained from curcuma longa, glycyrrhiza glabara, hamiltonia suaveolens, typha angustifolia and azadirachta indica, along with optionally comprising pig fat in sesamum indicum (til) oil as a base, useful for the treatment of wound healing. The present invention also discloses a process for preparation of said herbal composition..
12/05/13
20130323201
Combination treatments and compositions for wound healing
Viral vegf and viral anti-inflammatory cytokine compositions, methods of treatment using them, and kits containing them for use in the promotion and/or improvement of wound healing and/or tissue repair, and for anti-scarring, anti-inflammatory, anti-fibrosis and anti-adhesion indications.. .
12/05/13
20130323183
Absorbent dressings with painkilling activity
The invention discloses pharmaceutical compositions in the form of a dusting powder or dry spray, possessing a high absorbent capacity, painkilling activity and wound-healing action, which compositions consist of croscarmellose sodium, a non-steroidal anti-inflammatory drug (nsaid) and hyaluronic acid, and optionally also contain other pharmacologically active substances and/or excipients. The compositions disclosed herein are suitable for use in the treatment of skin lesions wherein the presence of exudate limits wound healing and causes pain; they are therefore particularly suitable for chronic ulcerous skin lesions of various origins and burns..
11/21/13
20130310776
Application of polymeric materials to screens to facilitate hemostasis and wound healing
This invention relates in general to a method and device for facilitating hemostasis and wound healing. In particular, the invention relates to the device comprising a polymeric material disposed on a scaffold that facilitates hemostasis and wound healing.
11/21/13
20130310381
Substituted sodium-1h-pyrazole-5-olate
The present application relates to sodium 1-[6-(morpholin-4-yl)pyrimidin-4-yl]-4-(1h-1,2,3-triazol-1-yl)-1h-pyrazol-5-olate, to processes for its preparation, to its use for the treatment and/or prophylaxis of diseases and to its use for the preparation of medicaments for the treatment and/or prophylaxis of diseases, in particular cardiovascular and haematological diseases and kidney diseases, and for promoting wound healing.. .
11/21/13
20130310327
Histatin for corneal wound healing and ocular surface disease
Histatins may be used for corneal wound healing and as a treatment for ocular surface disease in humans and other animals. For example, histatins could be included in eye drops, eye gels, ointment, glue, or embedded in (polymer) contact lenses..
11/21/13
20130310326
Histatin for corneal wound healing and ocular surface disease
Histatins may be used for corneal wound healing and as a treatment for ocular surface disease in humans and other animals. For example, histatins could be included in eye drops, eye gels, ointment, glue, or embedded in (polymer) contact lenses..
11/21/13
20130309286
Glucan compositions
The present invention relates to a gel composition comprising a glucan and a gelling agent, said composition having a melting point (gel to sol) above 37° c., as well as to the uses of this composition in therapy, in particular in wound healing.. .
11/14/13
20130303975
Wound treatment device
The current invention discloses a wound treatment device having a wound covering member, an applicator unit, and two lumens. The wound covering member may cover a wound.
11/14/13
20130302378
Matrix metalloproteinase inhibitors
The present invention relates to β-hydroxy and amino-substituted carboxylic acids, which act as matrix metalloproteinase inhibitors, particularly diastereomerically pure β-hydroxy carboxylic acids, corresponding processes for their synthesis, and pharmaceutical compositions containing the compounds of the present invention. Compounds of the present invention are useful in the treatment of various inflammatory, autoimmune, and allergic diseases, such as methods of treating asthma, rheumatoid arthritis, copd, rhinitis, osteoarthritis, psoriatic arthritis, psoriasis, pulmonary fibrosis, wound healing disorders, pulmonary inflammation, acute respiratory distress syndrome, perodontitis, multiple sclerosis, gingivitis, atherosclerosis, neointimal proliferation, which leads to restenosis and ischemic heart failure, stroke, renal diseases, tumor metastasis, and other inflammatory disorders characterized by the over-expression and over-activation of a matrix metalloproteinase..
11/14/13
20130302335
Ligands that bind tgf-beta receptor ii
The disclosure provides an anti-tgfbetarii immunoglobulin single variable domain. Suitably, an anti-tgfbetarii immunoglobulin single variable domain in accordance with the disclosure is one having an amino acid sequence as set forth in any one of seq id no:1-28 having up to 5 amino acid substitutions, deletions or additions.
11/14/13
20130300018
Polyhydroxyalkanoate medical textiles and fibers
Absorbable polyester fibers, braids, and surgical meshes with prolonged strength retention have been developed. These devices are preferably derived from biocompatible copolymers or homopolymers of 4-hydroxybutyrate.
11/07/13
20130296530
Use of peptides for promoting wound healing
The current invention relates to the use of a peptide comprising an amino acid sequence in the preparation of a medicament for the regeneration of tissue, preferably for the treatment of a wound. Further the invention relates to compositions comprising such peptides, and use of said peptides in both medical and nonmedical (cosmetic) applications..
11/07/13
20130296266
Pharmaceutical composition of complex carbohydrates and essential oils and methods of using the same
The invention discloses the discovery that a pharmaceutical composition containing complex carbohydrates with or without natural or synthetic essential oils can work effectively as a topical, oral or mucosal pharmaceutical composition. Such pharmaceutical compositions reduce inflammation, assist in wound healing, protect against bruising, relieve itching, relieve pain and swelling and treat topical bacterial infections such as acne and decubitus ulcers and prevent and treat numerous other conditions and diseases.
11/07/13
20130296239
Material for wound healing and skin reconstruction
The invention relates to a material for wound healing and skin reconstruction containing a peptide, wherein the peptide is a self-assembling peptide which is an amphiphilic peptide having 8 to 200 amino acid residues with periodic repeats of alternating hydrophilic amino acids and hydrophobic amino acids, and forms a stable β-sheet structure in an aqueous solution in the presence of a monovalent ion. The material for wound healing and skin reconstruction of the present invention is capable of healing a wound area of mammals quicker than spontaneous recovery without leaving any scars, wherein the material has no potential risk of infectious disease such as virus transmission..
11/07/13
20130295161
Compositions and methods for wound healing
The present invention is related to the field of wound healing or tissue regeneration due to disease (i.e., for example, cardiovascular diseases, osteoarthritic diseases, or diabetes). In particular, the present invention provides compositions and methods comprising molecules with linked α-gal epitopes for induction of an inflammatory response localized within or surrounding damaged tissue.
11/07/13
20130295141
Matrix metalloproteinase inhibitors
The present invention relates to β-hydroxy and amino-substituted carboxylic acids, which act as matrix metalloproteinase inhibitors, particularly diastereomerically pure β-hydroxy carboxylic acids, corresponding processes for their synthesis, and pharmaceutical compositions containing the compounds of the present invention. Compounds of the present invention are useful in the treatment of various inflammatory, autoimmune, and allergic diseases, such as methods of treating asthma, rheumatoid arthritis, copd, rhinitis, osteoarthritis, psoriatic arthritis, psoriasis, pulmonary fibrosis, wound healing disorders, pulmonary inflammation, acute respiratory distress syndrome, perodontitis, multiple sclerosis, gingivitis, atherosclerosis, neointimal proliferation, which leads to restenosis and ischemic heart failure, stroke, renal diseases, tumor metastasis, and other inflammatory disorders characterized by the over-expression and over-activation of a matrix metalloproteinase..
11/07/13
20130295081
Polyurethane composite for wound healing and methods thereof
The presently-disclosed subject matter includes polyurethane composites that include tissue component(s), as well as methods of making such composites and uses thereof. The polyurethane component can comprise a polyisocyanate prepolymer and a polyol.
11/07/13
20130295058
Pharmaceutical compositions comprising gingiva a-derived mesenchymal stem cells and methods of treating inflammation, wound healing and contact hypersensitivity
Disclosed are methods of polarizing macrophages to exhibit m2 phenotype, including introducing an effective amount of gingiva-derived mesenchymal stem cells to an environment comprising a population of macrophages such that the macrophages are in fluid communication with the gingiva-derived mesenchymal stem cells. Also disclosed are methods of promoting cutaneous wound healing including administering to a patient an effective amount of human gingiva-derived mesenchymal stem cells, thereby resulting in at least one of accelerated wound closure, rapid re-epithelialization, improved angiogenesis and improved tissue remodeling relative to untreated controls.
10/31/13
20130289724
Amnion and chorion wound dressing and uses thereof
An improved wound dressing is described. The wound dressing contains an allograft having at least one layer of human amnion and chorion tissues that has a size and shape appropriate for covering a wound, a base sheet for securing the allograft over the wound, and optionally a support layer to protect the allograft.
10/31/13
20130289059
Beneficial effects of increasing local blood flow
The present invention generally relates to the improvement of tissue health by increasing local blood flow. In some aspects of the invention, increased local blood flow is effected by the transdermal delivery of the nitric oxide precursor l-arginine and/or its derivatives alone, or optionally in conjunction with an adjunct such as theophylline.
10/31/13
20130288965
Use of peptides for promoting wound healing
The current invention relates to the use of a peptide comprising an amino acid sequence in the preparation of a medicament for the regeneration of tissue, preferably for the treatment of a wound. Further the invention relates to compositions comprising such peptides, and use of said peptides in both medical and nonmedical (cosmetic) applications..
10/31/13
20130288964
Use of peptides for promoting wound healing
The current invention relates to the use of a peptide comprising an amino acid sequence in the preparation of a medicament for the regeneration of tissue, preferably for the treatment of a wound. Further the invention relates to compositions comprising such peptides, and use of said peptides in both medical and nonmedical (cosmetic) applications..
10/31/13
20130287873
Pharmaceutical composition and method for preparing a medication for promoting wound healing
The disclosure provides a pharmaceutical composition for promoting wound healing, including an effective amount of a sambucus plant or an isatis plant as an active ingredient for promoting wound healing; and a pharmaceutically acceptable carrier or medium, wherein the sambucus plant is sambucus formosana nakai, and the isatis plant is isatis indigotica fort.. .
10/31/13
20130287839
Use of the cathelicidin ll-37 and derivatives thereof for wound healing
Use of the antimicrobial cathelicidin peptide ii-37, n-terminal fragments of ll-37 or extended sequences of ll-37 having 1-3 amino acids in the c-terminal end, for stimulating proliferation of epithelial and stromal cells and thereby healing of wounds, such as chronic ulcers. The cytotoxic effect of ll-37 may be reduced by including a bilayer-forming polar lipid, especially a digalactosyldiacylglycerol, in pharmaceutical compositions and growth media comprising ll-37..


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Wound Healing topics: Wound Healing, Amino Acid, Amino Acid Sequence, Proliferation, Theophylline, Inflammation, Antimicrobial, Epithelial, Amino Acids, Skin Graft, Bone Healing, Vascular Disease, Skin Ulcer, Bacterial Infection, Dysfunction

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