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Wound Healing patents



      
           
This page is updated frequently with new Wound Healing-related patent applications.



Date/App# patent app List of recent Wound Healing-related patents
02/04/16
20160030624 
 Methods and compositions for wound healing patent thumbnailnew patent Methods and compositions for wound healing
The present invention relates to methods and compositions for wound healing. In particular, the present invention relates to promoting and enhancing wound healing by utilizing cross-linker covalent modification molecules to attach and deliver wound active agents to a wound.
Imbed Biosciences, Inc.


02/04/16
20160030564 
 Biophotonic materials and uses thereof patent thumbnailnew patent Biophotonic materials and uses thereof
The present disclosure provides topical biophotonic materials and methods useful in phototherapy. In particular, the topical biophotonic materials of the present disclosure include a cohesive matrix, and at least chromophore which can absorb and emit light from within the topical biphotonic material, wherein the topical biophotonic material is elastic.
Klox Technologies Inc.


02/04/16
20160030525 
 Erythropoietin and fibronectin compositions for therapeutic and cosmetic applications patent thumbnailnew patent Erythropoietin and fibronectin compositions for therapeutic and cosmetic applications
A method of promoting wound healing or connective tissue reconstruction and a method of treating ischemia in a subject in need thereof are disclosed. The methods comprising topically administering to the subject about 10-30 mg per cm2 wound tissue of erythropoietin and about 100-300 mg per cm2 wound tissue of fibronectin, thereby promoting wound healing or connective tissue reconstruction or treating ischemia in the subject.
Remedor Biomed Ltd.


02/04/16
20160030496 
 Therapeutic viral microparticles for promoting stent biofunctionality and wound healing in vertebrate individuals patent thumbnailnew patent Therapeutic viral microparticles for promoting stent biofunctionality and wound healing in vertebrate individuals
The present disclosure provides viral microparticles comprising genetically-engineered baculoviruses (at least partially) embedded in a polymeric matrix for the local delivery of therapeutic nucleic acid molecules to the cells of a vertebrate individual (optionally in combination with a medical implant such as vascular stent platform). The viral microparticles are especially useful for promoting the healing of a wound as well as the repair of a blood vessel and prevent pathological scarring.
Mangogen Pharma Inc.


02/04/16
20160030476 
 Compositions, methods and devices for promoting wound healing and reducing infection patent thumbnailnew patent Compositions, methods and devices for promoting wound healing and reducing infection
Compositions, methods and devices are provided for promoting healing and preventing and treating infection in mammalian subjects. The compositions include pharmacologically active, protease inhibiting, cytokine protecting, aqueous media soluble sulfonated materials, optionally associated with one or more secondary therapeutic agents or carriers, to reduce one or more of inflammation, bacterial proliferation and proteolytic activity.
Iasis Molecular Sciences


01/28/16
20160023997 
 Absorbable polyurethanes and methods of use thereof patent thumbnailAbsorbable polyurethanes and methods of use thereof
Disclosed are novel bioabsorbable and biodegradable monomer compounds, bioabsorbable and biodegradable polymers therefrom, and methods of making such monomers and polymers, which are useful in pharmaceutical delivery systems, tissue engineering applications, tissue adhesives products, implantable medical devices, foams and reticulated foams for wound healing and drug delivery, bone hemostats and bone void fillers, adhesion prevention barriers, meshes, filters, stents, medical device coatings, pharmaceutical drug formulations, consumer product and cosmetic and pharmaceutical packaging, apparel, infusion devices, blood collection tubes and devices, other medical tubes, skin care products, and transdermal drug delivery materials.. .
Bezwada Biomedical, Llc


01/28/16
20160022773 
 Methods for promoting wound healing and hair growth patent thumbnailMethods for promoting wound healing and hair growth
The present invention generally relates to uses of glial cell line-derived growth factor (gdnf) in cutaneous wound healing and hair growth. Methods of effecting hair growth and/or wound healing which feature administration of gdnf, or a biologically active fragment thereof, to subjects, e.g., human subject, are disclosed herein.
The Jackson Laboratory


01/28/16
20160022759 
 Methods for increasing the selective efficacy of gene therapy using car peptide and heparan-sulfate mediated macropinocytosis patent thumbnailMethods for increasing the selective efficacy of gene therapy using car peptide and heparan-sulfate mediated macropinocytosis
Disclosed are compositions and methods for triggering disease selective macropinocytosis. The compositions can serve as a marker of disease activity and as a trigger of enhanced macropinocytosis in tissues undergoing disease remodeling such as wound healing, cancer, pah, inflammation, diabetes, crohn's disease, ulcerative colitis, ankylosing spondylitis, diseases of the endometrium, psoriasis, irritable bowel syndrome, arthritis, fibrotic disorders, interstitial cystitis, autoimmune diseases, asthma, acute lung injury, and adult respiratory distress syndrome.
Vascular Biosciences


01/28/16
20160022735 
 Methods and compositions for promoting wound healing patent thumbnailMethods and compositions for promoting wound healing
The present invention provides methods and compositions that use the combination of tris and edta to inhibit the growth of microorganisms at the site of a wound or burn, and/or to promote the healing of a wound or burn, and/or to reduce the sensation of pain at the site of a wound or burn. The amount of tris and edta applied to a wound or burn can be selected to achieve one or more of the foregoing effects..
The University Of Georgia Research Foundation, Inc.


01/28/16
20160022730 
 Compositions and methods of use for wound healing patent thumbnailCompositions and methods of use for wound healing
Described herein are a solution, composition, and kit of poly (acetyl, arginyl) glucosamine (paag), methods of making the solution, and method of treating wounds with the solution, the method comprising administering to a subject an effective amount of a solution comprising paag, wherein the paag when administered topically contacts the wound, thereby treating the wound.. .
Synedgen Inc.


01/21/16
20160015962 

Smart patch for wound management


A flexible patch is provided that is capable of emitting light in the uv, visible, and/or infrared electromagnetic spectrums. The patch contains a feedback process and system using one or more sensors and a controller on the patch to (1) accelerate the wound healing process by providing adaptable, controlled light exposure and electrical stimulation, (2) monitor the healing process for signs of infection (3) eliminate bacterial infections by sanitizing the infected site and (4) relaying the information wirelessly to a central location for storage and interpretation by a physician as well as by providing the ability to receive feedback and operating instructions from the physician from a remote location..

01/21/16
20160015791 

Use of angiogenin or angiogenin agonists for treating diseases and disorders


The invention provides a method of treating a disorder characterised by elevated or dysregulated myostatin, disorders where the interaction between follistatin and angiogenin can be used to improve function in tissues, neurological diseases or disorders, spinal injuries or diseases, bone diseases or disorders, diseases involving glucose homeostasis, wound healing, neuroprotection, nervous system functional support or managing metabolic diseases, the method comprising administering an effective amount of angiogenin or an angiogenin agonist. Compositions and neutraceuticals comprising angiogenin are also provided..
Murray Goulburn Co-operative Co., Limited


01/21/16
20160015592 

Micromechanical force devices for wound healing acceleration


An apparatus provides micromechanical forces on a wound bed to accelerate healing of a wound. The apparatus includes a pressure chamber having a substantially airtight plunger and an inlet fluidly connected to a first end of a conduit.
The Brigham And Women's Hospital


12/31/15
20150376623 

Antisense oligonucleotides directed against connective tissue growth factor and uses thereof


This invention provides compounds which comprise modified oligonucleotides capable of inhibitory expression of connective tissue factor and composition containing same as well as methods of treating hyperprolific disorders and fibrotic diseases, and of reducing scarring resulting from wound healing using such compounds.. .
Isis Pharmaceuticals, Inc.


12/31/15
20150376599 

Non-contact accelerating wound healing


An apparatus and method for accelerating the migration of cells by applying a time-varying magnetic field to induce eddy currents that promote electrotaxis (galvanotaxis) of cells. The apparatus and method of the present invention accelerates the healing of wounds by electrotaxis of cells.
Ohio State Innovation Foundation


12/31/15
20150374720 

Methods and products for increasing the rate of healing of tissue wounds


Disclosed are methods for increasing the rate of healing of a tissue wound by administering a composition including a therapeutically effective amount of at least one cationic steroid antimicrobial (csa). Also disclosed herein are methods of promoting wound healing in a subject in need of such promotion, comprising administering a composition comprising a therapeutically effective amount of at least one csa.
Brigham Young University


12/31/15
20150374641 

Film-forming pharmaceutical composition for wound healing and preparing the same


The present invention relates to a pharmaceutical composition for forming a film directly on a wound to accelerate wound healing, a use for the same, a treatment method using the same, and a method for preparing the same. The film-forming composition according to the present invention forms a film directly on the wound to increase the adhesion to the wound.
Dong-a Pharmaceutical Co., Ltd


12/24/15
20150367024 

Nanofibrillar polysaccharide for use in the control and prevention of contraction and scarring


The present invention relates to nanofibrillar polysaccharide hydrogels for use in the prevention and control of scarring and contraction in connection with wound healing or tissue repair.. .
Upm-kymmene Corporation


12/17/15
20150361176 

Ligands that bind tgf-beta receptor ii


The disclosure provides an anti-tgfbetarii immunoglobulin single variable domain. Suitably, an anti-tgfbetarii immunoglobulin single variable domain in accordance with the disclosure is one having an amino acid sequence as set forth in any one of seq id no:1-28 having up to 5 amino acid substitutions, deletions or additions.
Glaxo Group Limited


12/17/15
20150359842 

Pro-angiogenic fragments of prominin-1 and uses thereof


Described have herein are peptide analogs of a prominin-1 peptide, drvqrqtttvva (seq. Id.
Children's Medical Center Corporation


12/17/15
20150359764 

Methods of treatment using 3-bromopyruvate and other selective inhibitors of atp production


The present invention provides methods for preventing or treating infections, especially bacterial infections, by administering selective inhibitors of atp production to inhibit glycolytic enzymes, such as glyceraldehyde 3-phosphate dehydrogenase (gapdh). As such, the present invention further provides methods for preventing or treating inflammation and sepsis associated with infections, as well as increased wound healing and decreased wound scarring..
Prescience Labs, Llc


12/10/15
20150353605 

Short bio-active peptides for promoting wound healing


Peptides having four to six amino acid residues are disclosed that possess biological activity. These peptides constitute short fragments of the peptide hb-107 (mpkekvflkiekmgrnirn), which itself is a fragment of the antimicrobial protein cecropin b, and exhibit cell stimulatory and migratory properties.
Helix Biomedix, Inc.


12/10/15
20150352183 

Laminins, derivatives, and compositions including same and methods for their therapeutic use


In various embodiments, the present disclosure provides a method of treating a subject using laminin or a composition that includes laminin. In one embodiment, the method is used to enhance muscle regeneration, maintenance, or repair in a subject.
Board Of Regents Of The Nevada System Of Higher Education, On Behalf Of The University Of Nevada


12/10/15
20150352152 

Fluid associated with adult stem cells for medical, cosmetic, and veterinary use


Apparatus and process to create, expand, and localize the population of stem cells in adult tissues by placing a foreign body either in omentum or in the subcutaneous tissue. The apparatus 1) traps the granulation fluid, cells a fluid rich in a myriad of growth factors, 2) mobilizes and concentrates free-floating stem cells in the granulation fluid and 3) stimulates the growth of a new tissue around the apparatus, which provides another source of stem cells.

12/10/15
20150352151 

Activated leukocyte composition and uses for wound healing


Disclosed are therapeutic, blood-derived activated leukocyte compositions, methods of making them, and methods of using the compositions to repair or promote the prevention and healing of wounds.. .
Macrocure Ltd.


12/03/15
20150346216 

Devices and methods for the diagnosis and treatment of wounds using biomarkers


The present invention provides for devices and methods for determining the healing phase of a wound. In some aspects, the present invention provides a wound diagnosis device comprising a surface and at least one agent that is specific to a desired biomarker.
Kci Licensing, Inc.


12/03/15
20150342966 

Na/k-atpase ligand and uses thereof in wound healing


Methods and compositions for detecting, treating, characterizing, and diagnosing interstitial lung and/or fibrotic diseases are described.. .
The University Of Toledo


12/03/15
20150342179 

Compositions for internal and external use as an insecticide, ovicide, repellent and for wound healing


Exemplary embodiments of the present invention relate to pesticides, insecticides, insect repellant, insect anti-feeding, cleaning, glue dissolving and anti-irritation and wound healing compositions for humans and animals and, more particularly, to such compositions which are effective in killing, removing and/or repelling a wide range of endoparasites, ectoparasites and insects while also being non-toxic to humans, animals, and the environment. An exemplary embodiment of the present invention is directed to an aqueous composition including a mixture of at least one ethanolamide and at least one esterified fatty acid.
Natureza, Inc.


11/26/15
20150335917 

Wound treatment apparatus and method


An apparatus for cleansing wounds in which irrigant fluid from a reservoir connected to a conformable wound dressing and wound exudate from the dressing are moved by a device (which may be a single pump or two pumps) for moving fluid through a flow path which passes through the dressing and a means for providing simultaneous aspiration and irrigation of the wound. The apparatus also comprises means to apply high frequency vibrational energy, e.g.
Smith & Nephew Plc


11/26/15
20150335904 

Phototherapy devices and methods


The present disclosure relates to phototherapy device members which can be coupled to a light source to deliver light to hard to reach or internalized sites and which include a flexible fiber optic tip member having a core for transmitting light and an elastic tubular connector sleeve for mechanically coupling the flexible tip member to the light source. The present disclosure also relates to phototherapy devices which comprise the light source and the flexible fiber optic tip member.
Klox Technologies Inc.


11/26/15
20150335611 

Wound healing accelerator


The purpose of the present invention is to provide a specific wound healing accelerator effective for accelerating healing of wounds, particularly of wounds in the oral cavity, or a composition which includes the wound healing accelerator. This wound healing accelerator including a specific polyphenol is easy to handle and is capable of accelerating would healing even by contact for a short time..
A-z Ltd.


11/26/15
20150335492 

Chemically modified seacell fibres, wound dressing made therefrom and preparation method thereof


The present invention relates to a chemically modified cellulose/alginate co-spun (seacell) fibres, wound dressing made therefrom and preparation method thereof. The seacell fibres are subject to a chemical modification through which a hydrophilic carboxymethyl group is introduced into the cellulose structure making the chemically modified seacell fibres more absorbent.
Foshan Medical Technologies, Ltd.


11/19/15
20150329496 

Cdc42 inhibitor and uses thereof


Compounds which inhibit the small g protein rho gtpase cell division cycle protein cdc42 are provided. Morphological analyses of filopodia, western blots of ccd42 phosphorylation, and effects on cellular wound healing and on growth cone formation all demonstrate that the described compounds are able to inhibit all tested cdc42-mediated processes.

11/19/15
20150328288 

Methods of generating and using procollagen


A method of promoting wound healing, treating fibrosis and/or promoting angiogenesis is provided. The method comprises administering to a subject in need thereof a therapeutically effective amount of a procollagen, thereby promoting wound healing, treating fibrosis and/or promoting angiogenesis in the subject..
Collplant Ltd.


11/19/15
20150328268 

Marine plants extract for wound healing


This application is directed to a method of promoting wound healing comprising administering to a patient in need of such treatment an effective amount of fucus vesiculosus extract. The fucus visiculosus extract promotes wound angiogenesis, the process by which new blood vessels grow into tissues forming capillaries.
Basf Corporation


11/12/15
20150320905 

Wound healing compositions including cyanoacrylate monomers and phenytoin


A monomeric adhesive composition includes a stabilized polymerizable monomer, such as a 1,1-disubstituted monomer, including a cyanoacrylate, and a wound healing agent, wherein the wound healing agent is 5,5-disubstitutedhydantoin, including phenytoin; and a method for making said composition.. .
Adhezion Biomedical, Llc


11/12/15
20150320816 

Compositions for promotion of wound healing and/or scar reduction


The present invention relates to a wound healing and scar reduction composition that is a unique product with key ingredients carefully selected to optimize scar reduction. The composition when used can help reduce the appearance of old and new scars.
Trinity Pharma Group


11/05/15
20150315598 

Impaired wound healing compositions and treatments


Connexin modulation for the treatment of wounds that do not heal at expected rates, including delayed healing wounds, incompletely healing wounds, and chronic wounds, and associated methods, compositions and articles.. .
Coda Therapeutics, Inc.


11/05/15
20150314036 

Wound healing device


A plasma coating device for treating a wound comprises a plasma chamber having: one or more electrodes, a gas supply inlet, a plasma outlet exposed to ambient pressure, and an ignition system operatively connected to the electrodes for providing a non-thermal equilibrium plasma within the plasma chamber. An aerosol delivery system is operable to introduce a bioresorbable material as an aerosol into the plasma, to produce a coating on the wound surface..
Plasmedica Technologies Limited


11/05/15
20150313967 

Methods and agents for wound healing


This invention provides compositions and methods for topically treating skin wounds. The composition comprises c7, c7m, a variant thereof, or a combination thereof in a pharmaceutically acceptable carrier.
University Of Southern California


10/29/15
20150307840 

Endothelial and endothelial like cells produced from fibroblasts and uses related thereto


This disclosure relates to endothelial or endothelial like cells cultured from fibroblasts exposed to transcription factor etv2. In certain embodiments, the disclosure relates to methods of producing endothelial or endothelial like cells comprising exposing fibroblasts with etv2 under conditions such that the fibroblasts are modified to form a pool of cells expressing increased levels of endothelium surface markers compared to the fibroblasts.
The Board Of Trustees Of The University Of Illinois


10/29/15
20150306064 

Wound care products with peracid compositions


Methods have been developed for incorporation of a peracid compound into or on wound application matrices, such as bandages or dressings, and other matrices which will favorably impact wound healing and help eliminate microbial infection. The peracid compound comprises a base compound that is metabolically pertinent to wound healing, the oxidized form of the base compound (a peracid), and an appropriate oxidizer, such as hydrogen peroxide.
Chd Bioscience, Inc.


10/29/15
20150306055 

Antimicrobial composition


An antiseptic composition suitable for use on skin and wounds comprising a source of an antimicrobial agent and an agent which disrupts biofilms. More, particularly the invention relates to a composition capable of providing effective antimicrobial activity while at the same time avoiding wound and skin irritation and retardation of wound healing..
Convatec Technologies


10/29/15
20150305739 

Microstructure-based wound closure devices


The present invention relates generally to wound closure devices comprising one or more microstructures. The devices are designed such that the microstructures are able to grip the skin or tissue surrounding a wound, optionally closing the wound, or securing the tissue or skin in place.
University Of Washington Through Its Center For Commercialization


10/22/15
20150299174 

B- and y -diketones and y -hydroxyketones as wnt/ b -catenin signaling pathway activators


Which activates wnt/β-catenin signaling and thus treats or prevents diseases related to signal transduction, such as osteoporosis and osteoarthropathy; osteogenesis imperfecta, bone defects, bone fractures, periodontal disease, otosclerosis, wound healing, craniofacial defects, oncolytic bone disease, traumatic brain injuries related to the differentiation and development of the central nervous system, comprising parkinson's disease, strokes, ischemic cerebral disease, epilepsy, alzheimer's disease, depression, bipolar disorder, schizophrenia; eye diseases such as age related macular degeneration, diabetic macular edema or retinitis pigmentosa and diseases related to differentiation and growth of stem cell, comprising hair loss, hematopoiesis related diseases and tissue regeneration related diseases.. .

10/22/15
20150299157 

B- and y -diketones and y -hydroxyketones as wnt/ b -catenin signaling pathway activators


Which activates wnt/β-catenin signaling and thus treats or prevents diseases related to signal transduction, such as osteoporosis and osteoarthropathy; osteogenesis imperfecta, bone defects, bone fractures, periodontal disease, otosclerosis, wound healing, craniofacial defects, oncolytic bone disease, traumatic brain injuries related to the differentiation and development of the central nervous system, comprising parkinson's disease, strokes, ischemic cerebral disease, epilepsy, alzheimer's disease, depression, bipolar disorder, schizophrenia; eye diseases such as age related macular degeneration, diabetic macular edema or retinitis pigmentosa and diseases related to differentiation and growth of stem cell, comprising hair loss, hematopoiesis related diseases and tissue regeneration related diseases.. .

10/22/15
20150297808 

Negative pressure wound treatment device, and methods


A negative pressure (i.e., vacuum or suction) wound healing device and system incorporating the device. The device of the present disclosure is smaller, lighter, portable, and overall more managable by both the user and the medical personnel than the conventional systems.
Wound Care Technologies, Inc.


10/22/15
20150297785 

Wound healing material and application thereof


The present invention provides a wound healing material and its application thereof. The wound healing material comprises a hydrophobic fluoro-containing membrane having a first surface and a second surface opposing to each other; and at least one biocompatible polymer covalently bonded to at least one part of the first surface of the membrane wherein the membrane is air permeable but liquid impermeable and the water contact angle of the first surface formed with the biocompatible polymer is smaller than or equal to 40 degrees..
Chung Yuan Christian University


10/15/15
20150291954 

Organic compositions to treat beta-catenin-related diseases


The present disclosure relates to rnai agents useful in methods of treating beta-catenin-related diseases such as adenomatous polyposis of the colon, colorectal cancer, basal cell carcinoma, breast cancer, kidney cancer, wilms tumors, medulloblastoma, ovarian cancer, adrenocortical tumors, gastric cancer, liver cancer, melanoma, pancreatic cancers, prostate cancer, renal cancer, ectopic teeth and taste papillae, skin cancer, pilomatrixoma, anaplastic thyroid carcinoma, and uterine carcinosarcoma, oligodontia, osteoporosis, ageing, degenerative diseases, bedsores, chronic wounds and impaired wound healing, and similar and related diseases, using a therapeutically effective amount of a rnai agent to beta-catenin.. .

10/15/15
20150290354 

Nonwoven fiber materials


The present invention provides electrospun fibrous materials with various potential applications in the healthcare industry. Unique fiber morphologies are provided, which can allow the fibrous materials to exhibit a range of desirable properties.

10/15/15
20150290320 

Combination of an oxidant, a photosensitizer and a wound healing agent for oral disinfecton and treatment of oral disease


The present document describes methods of use of photo activated compositions for oral disinfection and/or treatments which comprise at least one oxidant, at least one photoactivator capable of activating the oxidant, and at least one healing factor chosen from hyaluronic acid, glucosamine and allantoin, in association with a pharmacologically acceptable carrier.. .

10/15/15
20150290289 

Method of promoting wound healing


Disclosed is a method of promoting wound healing or wound closure. The method comprises administration of a smir-198 inhibitor and/or a follistatin-like-1 (fstl1) polypeptide.

10/15/15
20150290041 

Wound dressing inhibiting lateral diffusion of absorbed exudate


A wound dressing including a hydrophilic layer and a hydrophobic layer is described. The hydrophilic layer absorbs exudate from a wound and the hydrophobic layer absorbs the exudate from the hydrophilic layer and traps the exudate.

10/15/15
20150289927 

Method and dermatological treatment and tissue reshaping


The present invention provides improved methods and apparatus for skin treatment and tissue remodeling. The apparatus includes an array of needles that penetrate the skin and serve as electrodes to deliver radio frequency current or other electrical or optical energy into the tissue being treated, causing thermal damage in controlled patterns.

10/08/15
20150284335 

Benzoimidazoles as prolyl hydroxylase inhibitors


Certain benzoimidazole compounds are described, which are useful as prolyl hydroxylase inhibitors. Such compounds may be used in pharmaceutical compositions and methods for the treatment of disease states, disorders, and conditions mediated by prolyl hydroxylase activity.

10/08/15
20150283290 

Sterilized compositions of cyanoacrylate monomers and naphthoquinone 2,3-oxides


Sterilized wound healing compositions comprise stabilized cyanoacrylate monomers homogenously mixed together with a naphthoquinone 2,3-oxide, including vitamin k oxides. The compositions are sterilized by irradiation, and the sterilized compositions are shelf stable such that their viscosity does not substantially increase following at least two years of shelf storage.

10/08/15
20150283287 

Methods and compositions for wound healing


The present invention relates to methods and compositions for wound healing. In particular, the present invention relates to promoting and enhancing wound healing by utilizing cross-linker covalent modification molecules to attach and deliver wound active agents to a wound.

10/08/15
20150283214 

Chimeric fibronectin matrix mimetics and uses thereof


The present invention is directed to recombinant fibronectin peptide mimetics and wound healing compositions containing the same. Other aspects of the present invention include wound healing dressings that comprise the wound healing composition of the present invention and a wound dressing material and methods of treating wounds using these compositions..

10/01/15
20150273014 

Use of peptides for promoting wound healing


The current invention relates to the use of a peptide comprising an amino acid sequence in the preparation of a medicament for the regeneration of tissue, preferably for the treatment of a wound. Further the invention relates to compositions comprising such peptides, and use of said peptides in both medical and nonmedical (cosmetic) applications..
Rapid Pathogen Screening, Inc.


10/01/15
20150273011 

Topical corneal analgesia using neurotensin receptor agonists and synergistic neurotensin combinations without delaying wound healing


A method for administering an ocular analgesic is described. The method includes the steps of providing a topical analgesic that includes a neo-tryptophan-containing neurotensin analog and applying the topical analgesic to the ocular tissue in a dose of about 0.0001 to about 5 mg, alternatively about 0.0001 to about 3 mg, alternatively about 0.0005 to about 1.2 mg, alternatively about 0.0005 to about 1.0 mg, alternatively about 0.00075 to about 1.0 mg, alternatively about 0.001 mg to about 1.0 mg, alternatively about 0.001 mg to about 0.8 mg, alternatively about 0.001 mg to about 0.7 mg, alternatively about 0.001 mg to about 0.6 mg.
Sloan-kettering Institute For Cancer Research


10/01/15
20150272997 

Mesenchymal stem cells and uses therefor


Methods of treating autoimmune diseases, allergic responses, cancer, or inflammatory diseases in an animal, promoting wound healing, repairing epithelial damage and promoting angiogenesis in an organ or tissue of an animal by administering to the animal mesenchymal stem cells in an effective amount.. .
Mesoblast International Sárl


10/01/15
20150272924 

Vitamin c, vitamin k, a polyphenol, and combinations thereof for wound healing


Provided herein is a method of promoting wound healing in a subject, comprising administering to the subject vitamin c, vitamin k, a polyphenol, or a combination thereof. Also provided herein is a method of treating a wound in a subject, comprising administering to the subject vitamin c, vitamin k, a polyphenol, or a combination thereof..
Summa Health System


09/24/15
20150265754 

Dressing and cleansing the wounds


A dressing (2) and an apparatus (1) comprising the dressing, for cleansing the wounds (5) in which an irrigant fluid from a reservoir (12) connected to a conformable would dressing and would exudate from the dressing are moved by a device (18) (which may be a single pump or two pumps) for moving fluid through a flow path (6, 7, 9, 10) which passes through the dressing with a means for providing simultaneous aspiration and irrigation of the wound, to provide a desired balance of fluid at a controlled nominal flow rate that removes materials deleterious to wound healing, while distributing materials that are beneficial in promoting would healing over the would bed.. .
Smith & Nephew Plc


09/24/15
20150265182 

Implantable biosensor and methods of use thereof


Disclosed herein is an analyte sensing device capable of continuously monitoring metabolic levels of a plurality of analytes. The device comprises an external unit, which, for example, could be worn around the wrist like a wristwatch or could be incorporated into a cell phone or pda device, and an implantable sensor platform that is suitable, for example, for implantation under the skin.
Optoelectronics Systems Consulting, Inc.


09/10/15
20150250922 

Polymeric hydrogel for accelerating wound healing


A method for creating a polymeric hydrogel for accelerating wound healing. The method includes applying at least one monomer solution to a tissue area of a patient.

09/10/15
20150250699 

Trpv3 agonists for the treatment of skin conditions


Described are methods and uses of trpv3 agonists for the treatment of conditions associated with trpv3 pathophysiology such as acne, psoriasis, dermatitis, would healing, the inhibition of hair growth, anxiety or depression. Peptides comprising all or part of the c-terminal portion of soricidin are shown to activate trpv3 cation channel activity and/or promote wound healing in keratinocytes..

09/10/15
20150250478 

Films, kits and methods for enhancing tissue treatment by plasma welding


Films made of biocompatible material selected to enhance tissue treatment by plasma welding are provided. The films may be reinforced in various ways, adhesively attached to various tissues and participate in treating processes such as wound closure and fixation, wound healing and organ welding, supported by plasma application which enhances treatment as well as attachment of the films to the tissues.
Ionmed Ltd.


09/10/15
20150250416 

Apparatus and method to assess wound healing


A device and method for measuring wounds is provided. The device includes a guide having cross-hairs that are positioned on a wound.
Vasamed, Inc.


09/03/15
20150246155 

Methods and compositions for promoting wound healing


The present invention provides methods and compositions that use the combination of tris and edta to inhibit the growth of microorganisms at the site of a wound or burn, and/or to promote the healing of a wound or burn, and/or to reduce the sensation of pain at the site of a wound or burn. The amount of tris and edta applied to a wound or burn can be selected to achieve one or more of the foregoing effects..
The University Of Georgia Research Foundation,inc.


09/03/15
20150246127 

Chromophore combinations for biophotonic uses


The present disclosure provides biophotonic compositions and methods useful in phototherapy. In particular, the biophotonic compositions of the present disclosure comprise at least two xanthene dyes.
Klox Technologies Inc.


08/27/15
20150238666 

System for tissue dissection and aspiration


A dermatological skin treatment device is provided. The device comprises a handpiece and a cutting tool, wherein the tool is inserted through the conduit and percutaneously inserted into a tissue disposed within a recessed area of the handpiece.
Ulthera, Inc.


08/27/15
20150238648 

Silver-copper-zinc oxide wound care system


A wound care system for promoting wound healing and for preventing infections thereof and a method for producing the same includes an anti-microbial solution and a multi-layer wound dressing. The anti-microbial solution contains a mixture of colloidal silver, colloidal copper and colloidal zinc mixed in sterile purified water.

08/27/15
20150238527 

Vitamin supplement compositions for injection


The embodiments relate to improved vitamin supplement compositions formulated for administration to patients, particularly improved vitamin compositions formulated for use in cosmetic or therapeutic applications. The compositions may be used to slow aging process and promote wellness including treating a vitamin deficiency, skin conditions, improving skin appearance, wound healing and scar prevention and hair loss..
Aquavit Pharmaceuticals, Inc.


08/27/15
20150238465 

Novel, protective, anti-inflammatory receptor and its use in preservation of mitochondrial function, wound healing and repair


Provided herein is a novel mitochondrial angiotensin ii type 1 and type 2 at1r and at2r receptor which plays a role in protection of mitochondria against oxidative damage. Evidence from animal studies indicates a role for this receptor in preservation of mitochondria and up-regulation of survival genes, anti-inflammatory action, and improvement of wound healing in the skin and soft tissues.
The Johns Hopkins University


08/27/15
20150237837 

Non-human model for wound healing


The present disclosure provides a rodent scar contracture model to study scar contractures and methods of using such a model. Such uses may include, but are not limited to, testing mechanisms or action or developing new anti-scar contracture compounds..
Duke University


08/20/15
20150231170 

Wound healing compositions comprising microspheres


Pharmaceutical or medical compositions for treating a wound are provided, the composition comprise microspheres as an active ingredient and water as a carrier for said microspheres. In some embodiments, compositions comprising a thickening agent dissolved within the water to form a solution having a specific gravity similar to that of the microspheres are provided..
Polyheal Ltd.


08/13/15
20150224167 

Composition for promoting wound healing


The present disclosure relates to a composition for promoting wound healing that may be used as a pharmaceutical composition, or a cosmetic composition for promoting wound healing, which contains a polypeptide including an amino acid sequence of seq id no 1. The composition may be usefully used for a wound care drug or a functional cosmetic product for wound care..
Industry-academic Cooperation Foundation, Yonsei University


08/06/15
20150218222 

Medicaments


The present invention relates to the use of a peptide, or derivative thereof of general formula x1—x2—x3-thr-x4-lys-x5-arg-x6 for promoting accelerated wound healing with reduced scarring. X1 is ala or gly; x2 is tyr or phe; x3, x4 and x5 are independently selected from the group comprising met, ile, leu and val; and x6 is selected from the group comprising asp, gln and glu..
Armo Biosciences, Inc.


08/06/15
20150217134 

Skin wound healing and hair growth


Disclosed are devices and methods that can help heal skin wounds and grow hair by irradiating light from light emitting diodes (led). One device is provided with: an ultra-narrowband light irradiation means which generates ultra-narrowband red light with peak wavelength range 620-660 nm and fwhm 10 nm or less; an ultra-narrowband light irradiation means which generates ultra-narrowband green light with peak wavelength range 500-540 nm and fwhm 10 nm or less; an ultra-narrowband light irradiation means which generates ultra-narrowband blue light with peak wavelength range 440-480 nm and fwhm 10 nm or less; and an ultra-narrowband light irradiation means which generates ultra-narrowband red to near infrared light with peak wavelength range 700-2500 nm and fwhm 10 nm or less.
Mignon Belle Co., Ltd.


08/06/15
20150216946 

Composition for reduced scar formation of wounds


A composition for reduced scar formation of wounds includes hydrolyzed collagen and one or more supplemental ingredients, including, lipoic acid, a zinc component, and a glucosamine component. The composition may facilitate inhibition of scar formation during wound healing.

08/06/15
20150216597 

Multiple beam laser treatment device


Embodiments of the invention include a treatment device and corresponding treatment method for laser wound healing, the device and method making use of the simultaneous action of multiple laser types and laser wavelengths which are applied at human tissue. The treatment device generally includes a laser system and a hand-piece which is coupled to the laser system.
Biolase, Inc.


08/06/15
20150216545 

Method and tissue harvesting


Exemplary methods and devices can be provided for harvesting a plurality of small tissue pieces, e.g., having widths less than about 1 mm or 0.5 mm, using one or more hollow needles. A fluid can be flowed through a conduit past the proximal ends of the needles to facilitate removal of the tissue pieces from the needle lumens, and can maintain the tissue pieces in a controlled and protective liquid environment.
The General Hospital Corporation


07/30/15
20150209564 

Ultrasound device and therapeutic methods


The present invention is directed to an ultrasound device for use in implementing therapeutic treatments and transdermal analyte delivery. The device includes a piezoelectric transducer that efficiently and safely converts electrical energy to ultrasonic waves, and has a unique structure including a piezoelectric element positioned between two opposing, flexible concave covers.
Drexel University


07/30/15
20150209492 

Apparatus for aspirating, irrigating and cleansing wounds


An apparatus for cleansing wounds in which irrigant fluid from a reservoir connected to a conformable wound dressing and wound exudate from the dressing are recirculated by a device for moving fluid through a flow path which passes through the dressing and a means for fluid cleansing and back to the dressing. The cleansing means (which may be a single-phase, e.g.
Smith & Nephew Plc


07/30/15
20150209478 

Articles for tissue regeneration with biodegradable polymer


The invention is to articles made from extracellular matrix sheets that encase biodegradable polymeric material. Methods of healing wounds or regenerating tissue at sites of defect by placing said articles in mammals are claimed.
Cormatrix Cardiovascular, Inc.


07/30/15
20150209069 

Scalpel


A scalpel for cutting soft tissues of the body with an abrasive trailing surface. The abrasive trailing surface reduces distinct scar formation by supporting wound healing.

07/23/15
20150202258 

Medicament for wound treatment


The invention relates to stathmin, stathmin, a nucleic acid encoding said stathmin or a cell expressing stathmin for use in the treatment of chronic wounds or disease- or medication-dependent impaired wound healing in a patient or for increasing or inducing the proliferation and/or migration of mesenchymal cells, of stem cells, for stimulating immune cells, preferably natural killer cells, for stimulating fibroblasts, for stimulating epithelial cells, preferably epithelial cells of the epidermis, or for stimulating angiogenesis.. .
Simu Trade Consulting Gmbh & Co. Leasing Kg


07/23/15
20150202251 

Multimeric tie 2 agonists and uses thereof in stimulating angiogenesis


The present invention provides a multimeric form of a tie 2 binding peptide monomer, wherein the multimeric form has tie 2 agonist activity. The multimeric form, preferably a tetramer, stimulates angiogenesis and promotes wound healing.
Sunnybrook Health Sciences Centre


07/16/15
20150197507 

4-aminoquinazolinyl compounds as prolyl hydroxylase inhibitors


Which are useful as prolyl hydroxylase inhibitors. Such compounds may be used in pharmaceutical compositions and methods for the treatment of disease states, disorders, and conditions mediated by prolyl hydroxylase activity.

07/16/15
20150196616 

Angiopoietin-like 4 and a its use in wound healing


A method and a pharmaceutical composition for increasing wound healing in an individual in need thereof, the method comprising administering an angiopoietin like 4 (angptl4) polypeptide or a therapeutically active fragment thereof.. .
Nanyang Technological University


07/09/15
20150190559 

Wound healing system using positive pressure to promote granulation at a tissue site


A wound healing system for promoting healing of a wound of a patient includes a positive pressure source, a reduced pressure source, and a porous foam positioned in contact with the wound. The porous foam includes a plurality of flow channels in fluid communication with the reduced pressure source.
Kci Licensing, Inc.


07/09/15
20150190504 

Wound healing


The present invention relates to the use of p38 map kinase inhibitors and p38 map kinase inhibition to promote wound healing.. .
Systagenix Wound Management (us), Inc.


07/09/15
20150190351 

Compounds with (1e, 6e)-1,7-bis-(3,4-dimethoxyphenyl)-4,4-disubstituted-hepta-1,6-diene-3,5-dione structural scaffold, their biological activity, and uses thereof


The present invention includes compounds, pharmaceuticals and cosmetics having at least one (substituted phenyl)-propenal moiety. The compounds and compositions of the present invention are useful in the treatment or prevention of medical conditions including androgen associated conditions, androgen associated inflammation, a wound (the compounds assist with wound healing), acne, rheumatoid arthritis, psoriasis, rosacea, and alopecia; kennedy's disease (spinal and bulbar muscular atrophy, or sbma), polyglutamine-mediated motor neuron degeneration; cancers such as prostate cancer, bladder cancer, breast cancer, ovarian cancer, hepatocellular (liver) cancer, and pancreatic cancer; and other medical conditions described herein.

07/02/15
20150183832 

Use of pedf-derived polypeptides for promoting stem cells proliferation and wound healing


Disclosed herein is a synthetic peptide, which has an amino acid sequence that has 20-39 amino acid residues. The synthetic peptide has at least 80% amino acid sequence identity to seq id no: 1, and includes at least 20 consecutive residues that has at least 90% amino acid sequence identity to residues 11-30 of seq id no: 1.
Mackay Memorial Hospital


07/02/15
20150182570 

Composition having a. paniculata for wound healing and skin whitening, and method by using the same


The present invention provides a pharmaceutical composition for wound healing and/or skin whitening. The pharmaceutical composition comprises active ingredient of andrographis paniculata extract and/or andrographolide and a pharmaceutical acceptable carrier.
National Dong Hua University


07/02/15
20150182554 

Surface active agent compositions and methods for enhancing oxygenation, reducing bacteria and improving wound healing at a site of treatment


This present invention relates generally to the use of novel formulations comprising a surface active polymer to enhance oxygenation in skin and other soft tissue. The present invention also discloses formulations that can be used to improve clinical outlook and reducing bacteria.
Plurogen Therapeutics, Inc.


06/25/15
20150174306 

Wound cleansing apparatus


An apparatus for cleansing and promoting tissue growth in wounds, in which irrigant fluid optionally containing cell nutrients and/or other physiologically active material from a reservoir connected to a conformable wound dressing and wound exudate from the dressing are recirculated by a device for moving fluid through a flow path which passes through the dressing, a biodegradable scaffold in contact with the wound bed and a means for fluid cleansing and back to the dressing. The apparatus has means for supplying thermal energy to the fluid in the wound.
Smith & Nephew Plc


06/25/15
20150174208 

Cosmetic and pharmaceutical composition with modified olygopeptides in form of supramolecular assembly


The invention is a cosmetic and pharmaceutical liposomal composition which comprises a mixture of carboxylated oligopeptides derived from natural polypeptides; insulin; hyaluronidase and collagenase by their enzymatic hydrolysis; followed by a carboxylation of the free amino groups of lysine, histidine, and additional hydrolysis of terminal amino groups in the oligopeptides. Natural polypeptides may be hydrolyzed with a proteolytic enzyme to form a mixture of oligopeptides and succinylated them.

06/25/15
20150174196 

Compositions and methods for wound healing and tissue repair


Provided are peptides that can inhibit collagen synthesis, processing and/or secretion from scar forming cells or fibroblasts. Also provided are methods for using the peptides to produce an anti-fibrotic, anti-scarring, anti-inflammatory, and/or pro-regenerative effect, e.g., on an injured or diseased tissue..
Musc Foundation For Research Development




Wound Healing topics: Wound Healing, Amino Acid, Amino Acid Sequence, Proliferation, Theophylline, Inflammation, Antimicrobial, Epithelial, Amino Acids, Skin Graft, Bone Healing, Vascular Disease, Skin Ulcer, Bacterial Infection, Dysfunction

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