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Wound Healing patents



      
           
This page is updated frequently with new Wound Healing-related patent applications. Subscribe to the Wound Healing RSS feed to automatically get the update: related Wound RSS feeds. RSS updates for this page: Wound Healing RSS RSS


Cosmetic and pharmaceutical composition with modified olygopeptides in form of supramolecular assembly

Date/App# patent app List of recent Wound Healing-related patents
06/25/15
20150174306
 Wound cleansing apparatus patent thumbnailnew patent Wound cleansing apparatus
An apparatus for cleansing and promoting tissue growth in wounds, in which irrigant fluid optionally containing cell nutrients and/or other physiologically active material from a reservoir connected to a conformable wound dressing and wound exudate from the dressing are recirculated by a device for moving fluid through a flow path which passes through the dressing, a biodegradable scaffold in contact with the wound bed and a means for fluid cleansing and back to the dressing. The apparatus has means for supplying thermal energy to the fluid in the wound.
Smith & Nephew Plc
06/25/15
20150174208
 Cosmetic and pharmaceutical composition with modified olygopeptides in form of supramolecular assembly patent thumbnailnew patent Cosmetic and pharmaceutical composition with modified olygopeptides in form of supramolecular assembly
The invention is a cosmetic and pharmaceutical liposomal composition which comprises a mixture of carboxylated oligopeptides derived from natural polypeptides; insulin; hyaluronidase and collagenase by their enzymatic hydrolysis; followed by a carboxylation of the free amino groups of lysine, histidine, and additional hydrolysis of terminal amino groups in the oligopeptides. Natural polypeptides may be hydrolyzed with a proteolytic enzyme to form a mixture of oligopeptides and succinylated them.
06/25/15
20150174196
 Compositions and methods for wound healing and tissue repair patent thumbnailnew patent Compositions and methods for wound healing and tissue repair
Provided are peptides that can inhibit collagen synthesis, processing and/or secretion from scar forming cells or fibroblasts. Also provided are methods for using the peptides to produce an anti-fibrotic, anti-scarring, anti-inflammatory, and/or pro-regenerative effect, e.g., on an injured or diseased tissue..
Musc Foundation For Research Development
06/25/15
20150173954
 Apparatus for aspirating, irrigating and cleansing wounds patent thumbnailnew patent Apparatus for aspirating, irrigating and cleansing wounds
An apparatus for cleansing wounds in which irrigant fluid from a reservoir connected to a conformable wound dressing and wound exudate from the dressing are recirculated by a device for moving fluid through a flow path which passes through the dressing and a means for fluid cleansing and back to the dressing. The cleansing means (which may be a single-phase, e.g.
Smith & Nephew Plc
06/18/15
20150165462
 Systems and methods for fabricating spiral coils with atomized bioactive coatings patent thumbnailSystems and methods for fabricating spiral coils with atomized bioactive coatings
Systems and methods for coating of spiral intracranial aneurysm coils, e.g., a guglielmi detachable coil (gdc), such that only selected surfaces along the spiral coil are coated with a polymer via an atomized polymer deposition process. The resulting device is a detachable aneurysm coil system which preserves the mechanical geometry and flexibility of the coil, and delivers specific agents to promote wound healing..
The Regents Of The University Of California
06/18/15
20150165101
 Wound cleansing apparatus in-situ patent thumbnailWound cleansing apparatus in-situ
An apparatus for cleansing wounds, in which wound exudate is removed from a wound bed and selectively cleansed and returned to the wound. The cleansing means removes materials deleterious to wound healing, and the cleansed fluid, still containing materials that are beneficial in promoting wound healing, is returned to the wound bed.
Smith & Nephew Plc
06/18/15
20150164994
 Systems and methods for angiogenic treatment in wound healing patent thumbnailSystems and methods for angiogenic treatment in wound healing
The invention relates to systems and methods for the diagnosis, amelioration, and treatment of ischemic tissues in patients caused by and/or resulting from diminished microvascular blood flow. Patients suffering from ischemic tissue conditions can be categorized into specific subsets that are deemed to have a potential to respond to therapy.
Cardiovascular Biotherapeutics, Inc.
06/18/15
20150164961
 Methods and compositions for treatment of penile defects patent thumbnailMethods and compositions for treatment of penile defects
A composition for use in treating penile defects, including erectile dysfunction and peyronie's disease, is provided. The composition includes adipose tissue and stem cells.
06/18/15
20150164064
 Methods, compositions and devices for inducing stasis in cells, tissues, organs, and organisms patent thumbnailMethods, compositions and devices for inducing stasis in cells, tissues, organs, and organisms
The present invention concerns the use of oxygen antagonists for inducing stasis in cells, tissues, and/or organs in vivo or in an organism overall. It includes methods and apparatuses for achieving stasis in any of these biological materials, so as to preserve and/or protect them.
Fred Hutchinson Cancer Research Center
06/11/15
20150158921
 Alphao-superfamily conotoxin peptide, pharmaceutical composition and use thereof patent thumbnailAlphao-superfamily conotoxin peptide, pharmaceutical composition and use thereof
The present invention pertains to fields of biochemistry and molecular biology, relates to an αo-superfamily conotoxin peptide, pharmaceutical composition thereof, preparation method and use thereof. The present invention further relates to a propeptide of the conotoxin peptide, nucleic acid construct thereof, expression vector and transformed cell thereof, and fusion protein thereof.
Hainan University
06/11/15
20150157583

Pharmaceutical composition


Pharmaceutical compositions comprising a plurality of ingredients that synergistically provide an antimicrobial, analgesic, or wound healing characteristic.. .
06/11/15
20150157508

Wound cleansing apparatus with scaffold


An apparatus for cleansing and applying therapy or prophylaxis to wounds, in which irrigant fluid containing a physiologically active material from a reservoir connected to a conformable wound dressing and wound exudate from the dressing are recirculated by a device for moving fluid through a flow path which passes through the dressing and a means for fluid cleansing and back to the dressing. A biodegradable scaffold underlies the dressing on the wound bed to promote tissue growth.
Smith & Nephew Plc
06/04/15
20150152138

Uses of kappa opioid synthetic peptide amides


The invention relates to methods of use of synthetic peptide amides that are ligands of the kappa opioid receptor in the treatment and prevention of kappa opioid receptor-associated diseases and conditions; and particularly to uses of these agonists in the prophylaxis, inhibition and treatment of pain, inflammation and pruritis associated with a variety of diseases, disorders and conditions. Inflammatory conditions preventable or treatable by the methods of the invention include diseases and conditions associated with elevated levels of a proinflammatory cytokines, such as tnf-α, il-1β, il-6, mmp-1 and mmp-3.
Cara Therapeutics, Inc.
06/04/15
20150150931

Method to facilitate healing of wounds


A method for treating wounds utilizing a dry powder mixture created using dry flour. The wound healing dry powder is created through the method of first heating dry flour over heat for a sufficient amount of time to undergo a chemical change wherein the flour changes color.
06/04/15
20150150925

Wound healing composite with a function of promoting the growth of granulation tissues


A composite with antibacterial and antipruritic functions includes a first substrate extracted from a plant, a second substrate and a base, and the first substrate includes a loniceraiaponica extract and an acanthopanax extract, and both loniceraiaponica extract and acanthopanax extract have a weight percentage ranging from 0.75 to 1.33, and the composite can effectively restrain the itch caused by skin pustules, folliculitis, and mosquito bites, and achieve the moisturization and antipruritic and anti-dander effects for mitigating the symptoms caused by candida albicans and staphylococcus aureus. In addition, this composite has good effects on general skin diseases such as hand eczema (ktpp), eczema, and lip herpes.
Li Tzu Pao Mei Regiman Beauty Public Ltd. Company
06/04/15
20150150924

Wound healing composite with a function of promoting the growth of granulation tissues


A wound healing composite with a function of promoting the growth of granulation tissues includes a substrate extracted from a plant and a base, and the substrate includes a loniceraiaponica extract, a mugwort extract, and ginkgo, and both loniceraiaponica extract and ginkgo have a weight percentage ranging from 0.28% to 3.5%. The wound healing composite can effectively promote the growth of granulation tissues, and loniceraiaponica, mugwort, ginkgo and other ingredients are extracts of natural plants, and thus the wound healing composite has a low drug resistance and does not have the side effect of drug allergy or the doubt leading to skin cancer..
Li Tzu Pao Mei Regiman Beauty Public Ltd. Company
05/28/15
20150148381

Substituted dihydropyrazolones for treating cardiovascular and hematological diseases


The present application relates to novel substituted dihydropyrazolone derivatives, processes for their preparation, their use for treatment and/or prophylaxis of diseases and their use for the preparation of medicaments for treatment and/or prophylaxis of diseases, in particular cardiovascular and hematological diseases and kidney diseases, and for promoting wound healing.. .
Bayer Intellectual Property Gmbh
05/28/15
20150148304

Novel peptides and analogs for use in the treatment of macrophage activation syndrome


Innate defense regulators (idrs) interact with intracellular signaling events and modulate the innate defense response. Whereas much of the initial work with the idrs focused on their role in fighting infection, recent results in animal models of chemotherapy- or radiation-induced mucositis and wound healing suggest that idrs can be beneficial during the responses to a broader range of damage-inducing agents beyond pathogens.
Soligenix, Inc.
05/21/15
20150141501

Ultrapure tetrahydrocannabinol-11-oic acids


This application is in the field of medicinal chemistry and relates to ultrapure ajulemic acid, its synthesis, pharmaceutical compositions and methods of use thereof for the treatment and/or prevention of inflammation, pain, and fibrotic diseases including scleroderma, systemic sclerosis, scleroderma-like disorders, sine scleroderma, liver cirrhosis, interstitial pulmonary fibrosis, idiopathic pulmonary fibrosis, dupuytren's contracture, keloids, chronic kidney disease, chronic graft rejection, and other scarring-wound healing abnormalities, post-operative adhesions, and reactive fibrosis.. .
Corbus Pharmaceutics Inc.
05/21/15
20150141430

Method for modulating canonical wnt pathway using folate and inositol


The canonical wnt signaling pathway is implicated in wound healing. Administration of a composition having myo-inositol and folic acid upregulates fibronectin and provides the greatest protection in an additive/synergistic manner against adverse wnt/β-catenin-mediated effects on cell processes relating to cell differentiation, proliferation, and migration that relate to wound healing..
University Of South Florida
05/21/15
20150140138

Decubitus treatment system


The present invention includes compositions and methods for cleaning, treating, protection and resolution of decubitus ulcers comprising: a first composition comprising a wound cleaning solution comprising aloe vera gel comprising at least 5,000 mps, a balanced salt solution; and a second composition comprising a wound healing gel comprising aloe vera gel comprising at least 10,000 mps, a thickening agent, and one or more preservatives and, optionally, a third composition comprising a moisture barrier cream comprising a vegetable-based emulsifier, a cosmetic ester for dry skin that has low occlusivity, an ester-based emollient that is oxidation stable and has low occlusivity; a beeswax; a hydrogenated oil, glycerin, a buffering agent, aloe vera gel comprising at least 2,000 mps and water.. .
Aloe Bioscience, Llc
05/21/15
20150140116

Bone implant materials comprising cross-linked bioactive hydrogel matrices


The present invention is directed to a stabilized cross-linked hydrogel matrix comprising a first high molecular weight component and a second high molecular weight component that are covalently linked, and at least one stabilizing or enhancing agent, wherein the first high molecular weight component and the second high molecular weight component are each selected from the group consisting of polyglycans and polypeptides. This stabilized hydrogel matrix may be prepared as bioactive gels, pastes, slurries, cell attachment scaffolds for implantable medical devices, and casting or binding materials suitable for the construction of medical devices.
Pioneer Surgical Technology, Inc.
05/21/15
20150140064

Nanoscale collagen particles and membranes


Nano scale collagen particles can be obtained from an embrittling and attrition process that reduces the size of collagen particles to the nano scale. These nano scale collagen particles have many favorable properties such as providing beneficial and enhanced properties for cell seeding and wound healing.
Empire Technology Development Llc
05/21/15
20150140060

Compositions and methods for promoting wound healing and tissue regeneration


Provided herein are compositions and methods for use in promoting wound healing and tissue regeneration following tissue injury in a subject.. .
Musc Foundation For Research Development
05/21/15
20150139962

Composition and stem cells for preservation of cardiac tissue


The method and composition may be used in medicine or cosmetic application, in particular, in treatment of cardiac tissue and/or cardiac diseases, and/or in the treatment of wound healing namely diabetic wound healing.. .
05/14/15
20150132805

Composition for producing microrna precursors as drugs for enhancing wound healing and production the microrna precursors


This invention generally relates to a composition and its production method useful for developing drugs and/or therapies for enhancing wound healing, in particular scarless wound healing. Particularly, the present invention teaches the essential processes necessary for producing and purifying embryonic stem cell (esc)-specific rna compositions, such as messenger rnas (mrna), microrna precursors (pre-mirna), and small hairpin rnas (shrna), which are useful for treating human diseases and lesions..
05/14/15
20150132362

Hemostatic sponge


The present invention provides a hemostatic porous sponge comprising a matrix of a fibrous biomaterial and particles of a fluid absorbing, particulate material adhered to said matrix material, a method of producing these sponges and their use for wound healing.. .
05/14/15
20150132240

Topical composition and skin treatment


A topical composition and method for skin treatment including a wound healing agent in combination with a wound concealing agent, is disclosed herein.. .
05/07/15
20150127041

Handpiece for use in tissue dissection


A dermatological skin treatment device is provided. The device comprises a handpiece and a cutting tool, wherein the tool is inserted through the conduit and percutaneously inserted into a tissue disposed within a recessed area of the handpiece.
Ulthera, Inc.
05/07/15
20150126447

Method and kit for the classification and prognosis of wounds


The present invention relates to a method and kit for the classification and prognosis of wounds of mammalian, in particular in human. The method defines a molecular signature that enables one to characterize a pathological wound healing such as chronic or non-healing wound..
Ecole Normale Superieure
04/30/15
20150119788

Biophotonic compositions, kits and methods


The present disclosure provides biophotonic topical compositions, kits and their uses. In particular, the biophotonic compositions of the present disclosure are substantially resistant to leaching such that very low amounts of chromophore(s) present in the biophotonic composition leach out of the composition.
Klox Technologies Inc.
04/30/15
20150118734

Inducible gene expression composition for using eukaryotic pol-2 promoter-driven transcription in prokaryotes and the applications thereof


Eukaryotic protein-coding messenger rnas and non-coding micrornas are naturally transcribed by type ii rna polymerases (pol-2) but not prokaryotic rna polymerases. As a result, current eukaryotic rna and protein production is performed either using eukaryotic pol-2 promoters in hybridomas or mammalian cells or using prokaryotic promoters in bacterial cells.
Mello Biotechnology, Inc.
04/23/15
20150110748

Bone grafts including osteogenic stem cells, and methods relating to the same


Bone grafts and constructs including stem cells are provided. Example bone grafts include osteogenic stem cells seeded on a scaffold of osteoconductive cortico-cancellous chips and/or osteoinductive demineralized bone.
Globus Medical, Inc.
04/23/15
20150110747

Bone grafts including osteogenic stem cells, and methods relating to the same


Bone grafts and constructs including stem cells are provided. Example bone grafts include osteogenic stem cells seeded on a scaffold of osteoconductive cortico-cancellous chips and/or osteoinductive demineralized bone.
04/16/15
20150105811

Methods for dissection of subcutaneous tissue


A dermatological skin treatment device is provided. The device comprises a handpiece and a cutting tool, wherein the tool is inserted through the conduit and percutaneously inserted into a tissue disposed within a recessed area of the handpiece.
Ulthera, Inc.
04/16/15
20150105447

Fidgetin-like 2 as a target to enhance wound healing


Methods of treating a wound in a subject are provided comprising administering to the subject an amount of an inhibitor of fidgetin-like 2. Compositions and pharmaceutical compositions comprising an amount of an inhibitor of fidgetin-like 2 are also provided.
Albert Einstein College Of Medicine Of Yeshiva University
04/16/15
20150105360

Therapeutic compositions and method


This invention relates the use of cortisol blockers (glucocorticoid receptor [gr] antagonists) for the prevention or addiction induced anxiety and withdrawal side effects as a therapeutic and in concert with a diagnostic. Such addictions could be, but are not limited to, alcohol, drugs, caffeine, sugar, food, nicotine, etc.
Pop Test Cortisol Llc
04/16/15
20150105319

Durable haemostatic scaffold


A method for preparing a haemostatic and adhesive durable scaffold useful for promoting wound healing, and the scaffold so prepared, are provided. The scaffold made of fibrinogen and chitosan is produced by electrospinning techniques, resulting in a material with enhanced endurance, applicable in various medical purposes including surgery, tissue regeneration, burns, injuries, and the like.
04/16/15
20150104492

Esculentin 1a derivatives and uses thereof


The present invention provides synthetic antibacterial peptides comprising a sequence at least 80% identical to a sequence shown in seq id no: 2 or the diastereomer thereof with a sequence shown in seq id no: 3 or pharmaceutical compositions thereof. Also provided are methods for reducing the severity of microbe-induced inflammation and for stimulating wound healing via the synthetic antibacterial peptides.
04/16/15
20150104482

Use of cpg oligonucleotides co-formulated with an antibiotic to accelerate wound healing


Pharmaceutical compositions are provided that include an antibiotics, but that include ingredients that counteract the effect of that antibiotic on wound healing, without altering the bactericidal properties of the antibiotic. These pharmaceutical compositions include an effective amount of 1) an imidazoquinoline having toll-like receptor 7 (tlr7) ligand activity, 2) an immunostimulatory k-type cpg oligodeoxynucleotide (odn) comprising an unmethylated cpg motif, 3) an antibiotic, and 4) a surfactant, wherein the composition is formulated for topical administration.
The United States Of America, As Represented By The Secretary, Department Of Health And Human Serv
04/09/15
20150098985

Wound dressings for the controlled release of therapeutic


A wound dressing material for controlled activation of a wound healing therapeutic compound in the presence of a protease enzyme in a wound fluid, the material comprising: a medically acceptable polymer; a wound healing therapeutic agent; an inhibitor of the protease enzyme; and a linker group which is cleavable by the protease enzyme, wherein the activities of both the wound healing therapeutic agent and the inhibitor are increased by contacting the wound dressing material with a would fluid containing the protease enzyme. For example, the enzyme may be a matrix metalloproteinase, the therapeutic agent may be a reactive oxygen scavenger, and the inhibitor may be a tissue inhibitor of metalloproteinase (timp)..
Systagenix Wound Management (us), Inc.
04/02/15
20150094330

Compounds and methods for skin repair


The invention provides compositions and methods for wound healing and scar reduction. The compositions and methods of the invention include at least one ep4 agonist set forth herein.
Allergan, Inc.
04/02/15
20150094260

Buffered ophthalmic compositions and methods of use thereof


The present disclosure provides a buffered ophthalmic composition for formulation of topically administrable suspensions useful for treating eye disorders by promoting wound healing, delivery of pharmaceutically active agents, and lubricating the eye. In particular the ophthalmic composition includes a buffer solution compatible with application to a mammalian eye, wherein the buffer provides increased mechanism of action of pharmaceutically active agents as well as therapeutic qualities.
Arava Bio-tech Ltd.
04/02/15
20150094256

Use of the cathelicidin ll-37 and derivatives thereof for wound healing


Use of the antimicrobial cathelicidin peptide ii-37, n-terminal fragments of ll-37 or extended sequences of ll-37 having 1-3 amino acids in the c-terminal end, for stimulating proliferation of epithelial and stromal cells and thereby healing of wounds, such as chronic ulcers. The cytotoxic effect of ll-37 may be reduced by including a bilayer-forming polar lipid, especially a digalactosyldiacylglycerol, in pharmaceutical compositions and growth media comprising ll-37..
Lipopeptide Ab
03/26/15
20150088231

Ocular treatment system and method using red and gold phototherapy


Systems and methods of ophthalmologic or ocular phototherapy treatment are provided herein. In some embodiments, the systems and methods of ophthalmic or ocular phototherapy treatment comprise applying a treatment light beam in a predetermined wavelength or wavelength range corresponding to gold (yellow to orange), red, or at least part of both the gold and red visible light wavelength ranges to at least a portion of an eye.
Cxl Ophthalmics, Llc
03/26/15
20150086605

Multi-layer biomaterial for tissue regeneration and wound healing


The technology described herein is directed to compositions comprising at least a first porous biomaterial layer and a second impermeable biomaterial layer and methods relating thereto. In some embodiments, the compositions and methods described herein relate to wound healing, e.g.
Tufts University
03/19/15
20150080787

Apparatus for aspirating, irrigating and cleansing wounds


An apparatus for cleansing wounds in which irrigant fluid from a reservoir connected to a conformable wound dressing and wound exudate from the dressing are recirculated by a device for moving fluid through a flow path which passes through the dressing and a means for fluid cleansing and back to the dressing. The cleansing means (which may be a single-phase, e.g.
Smith & Nephew Plc
03/19/15
20150080784

Method and device for treating a tissue with a high frequency electromagnetic field


Methods and systems for treating a tissue with a high frequency electric field to activate mapk/erk pathways, induce angiogenesis, induce angionenic factos such as no and vegf, or promote wound healing. Aspects of the invention are directed to methods of treating chronic wounds such as diabetic ulcers and hypoxia induced wounds.
University Of Cincinnati
03/19/15
20150080659

Systems and methods for introducing and applying a bandage structure within a body lumen or hollow body organ


Systems and methods provide intraluminal delivery of a bandage structure within a body lumen or hollow body organ, e.g., for treating an injured gastrointestinal tract or an esophageal hemorrhage in a non-invasive way using endoscopic visualization. The systems and methods can be sized and configured to apply a chitosan bandage structure within a body lumen or hollow body organ, to take advantage of the mucoadhesive, antimicrobial, hemostatic, and potential accelerated wound healing properties of the chitosan material..
Providence Health System - Oregon D/b/a Providence St. Vincent Medical Center
03/19/15
20150080314

Topical corneal analgesia using neurotensin receptor agonists and synergistic neurotensin combinations without delaying wound healing


Ocular analgesics for topical administration are described. The topical ocular analgesic includes a neo-tryptophan-containing neurotensin analog.
Sloan-kettering Institute For Cancer Research
03/19/15
20150080301

Absorbable polyurethanes and methods of use thereof


Disclosed are novel bioabsorbable and biodegradable monomer compounds, bioabsorbable and biodegradable polymers therefrom, and methods of making such monomers and polymers, which are useful in pharmaceutical delivery systems, tissue engineering applications, tissue adhesives products, implantable medical devices, foams and reticulated foams for wound healing and drug delivery, bone hemostats and bone void fillers, adhesion prevention barriers, meshes, filters, stents, medical device coatings, pharmaceutical drug formulations, consumer product and cosmetic and pharmaceutical packaging, apparel, infusion devices, blood collection tubes and devices, other medical tubes, skin care products, and transdermal drug delivery materials.. .
Bezwada Biomedical, Llc
03/19/15
20150079196

Wound dressing containing polysaccharides


A wound dressing makes use of polysaccharides, including the formation of a range of variable viscosity mixtures that use a solid polysaccharide such as medical grade cane sugar and a liquid polysaccharide such as honey, both of which have inherent beneficial properties for wound healing. The mixture is applied to an absorbent surface that is designed to absorb the mixed polysaccharide only partially..
Medline Industries, Inc.
03/19/15
20150079152

Composition and dressing for wound treatment


The invention provides methods and compositions for wound treatment and/or blood clot formation, e.g., arresting the flow of blood from an open wound. The methods and compositions provide for promoting and accelerating wound healing and optionally provide for inhibition of microbial infection and/or a local analgesic effect..
03/19/15
20150079143

Three-dimensional scaffolds for tissue engineering made by processing complex extracts of natural extracellular matrices


Methods of making a biologically active three-dimensional scaffold capable of supporting growth and differentiation of a cell are described. Biologically active three-dimensional scaffold made by the methods of the invention and an engineered tissue made from the scaffolds are described.
Drexel University
03/19/15
20150079134

Treatment to promote wound healing


The invention relates to a field of tissue repair and regeneration. More particularly, the invention relates to a composition for promoting cutaneous wound healing.
Rutgers, The State University Of New Jersey
03/12/15
20150073444

Polyhydroxyalkanoate medical textiles and fibers


Absorbable polyester fibers, braids, and surgical meshes with prolonged strength retention have been developed. These devices are preferably derived from biocompatible copolymers or homopolymers of 4-hydroxybutyrate.
Tepha, Inc.
03/12/15
20150073326

Hemostasis wound healing device for dynamic elastic injury site


A topical cooling compressive hemostasis wound healing device and methods thereof for affecting a percutaneous access site wound or an acute surgical wound. The device delivers and transports cooling to affect and control vasculature and musculoskeletal motions surrounding the injury site during the blood coagulation, hemostasis, and wound healing phases.
03/12/15
20150072966

Method of promoting wound healing


A method of establishing a therapeutic window of wound fluid nitric oxide (wfno) in the wound of a mammal, the method including: obtaining a wound fluid sample from a mammal; analyzing the wfno level; determining whether the wfno is at or below a lower threshold level, or is at or above an upper threshold level; wherein the lower threshold level and upper threshold level define the therapeutic window of wfno; and treating the mammal with a substance that alters the wfno level such that the therapeutic window of wfno in the wound is established.. .
3m Innovative Properties Company
03/12/15
20150072936

Methods for promoting wound healing and/or reducing scar formation


The present invention provides methods for promoting wound healing and/or reducing scar formation, by administering to an individual in need thereof one or more of the heat shock protein 20-derived polypeptides disclosed herein.. .
03/12/15
20150071869

Wound healing compositions including cyanoacrylate monomers and phenytoin


A monomeric adhesive composition includes a stabilized polymerizable monomer, such as a 1,1-disubstituted monomer, including a cyanoacrylate, and a wound healing agent, wherein the wound healing agent is 5,5-disubstitutedhydantoin, including phenytoin; and a method for making said composition.. .
Adhezion Biomedical, Llc
03/12/15
20150071856

Antagonistic peptides for frizzled-1 and frizzled-2


The invention is in the field of molecular medicine. It provides antagonistic compounds for frizzled-1 and/or frizzled-2 receptors, which may be useful in molecular imaging of the wound healing process after myocardial infarction and in therapeutic intervention into wound healing after remodeling of the heart, thereby ameliorating the consequences of myocardial infarction.
Academisch Ziekenhuis Maastricht
03/12/15
20150068531

Methods and devices for conduit occlusion


The present invention comprises systems. Methods and devices for the delivery of compositions for occluding or of elements for opening conduits.
Femasys Inc.
03/05/15
20150066011

Devices and methods for performing subcutaneous surgery


Devices and methods for performing subcutaneous surgery in a minimally invasive manner are provided. The methods include application of reduced air pressure in a recessed area of a handpiece placed over a section of skin and drawing the section of skin and subcutaneous tissue into the recessed area.
Ulthera, Inc.
03/05/15
20150065453

Combination of an oxidant and a photoactivator for the healing of wounds


There is provided a wound healing composition which comprises at least one oxidant, at least one photoactivator capable of activating the oxidant and at least one healing factor chosen from hyaluronic acid, glucosamine and allantoin in association with a pharmaceutically acceptable carrier. In addition, a method of topically treating wounds using at least one oxidant and at least one photoactivator capable of activating the oxidant followed by illumination of said photosensitizer is disclosed..
Klox Technologies Inc.
03/05/15
20150065429

Crosslinked human or animal tissue products and their methods of manufacture and use


Degradable bioprostheses made of collagen-based material having amine-based and ester-based crosslinks are provided, as are methods for their formation and use. Some embodiments of the present invention are directed towards a method of controlling the ratio of amine-based crosslinks to ester-based crosslinks within a collagen-based material to provide a tailorably crosslinked collagen-based material.
Harbor Medtech, Inc.
03/05/15
20150065428

Method for articular cartilage and joint formation


The invention is a method of applying a joint inducing protein preferably bmp-9 or bmp-3 to an ossification center in order to create a joint, articular cartilage, or an endochondral cap. The ossification center may be one that occurs naturally such as in the case of amputation, wound healing or fracture, or, it may be artificially induced by the application of an ossification center inducing protein, which may include other bmp family proteins such as bmp-2, bmp-4 or bmp-7.
03/05/15
20150064771

Inducible gene expression composition for using eukaryotic pol-2 promoter-driven transcription in prokaryotes and the applications thereof


Eukaryotic protein-coding messenger rnas and non-coding micrornas are naturally transcribed by type ii rna polymerases (pol-2) but not prokaryotic rna polymerases. As a result, current eukaryotic rna and protein production is performed either using eukaryotic pol-2 promoters in hybridomas or mammalian cells or using prokaryotic promoters in bacterial cells.
Mello Biotechnology, Inc.
03/05/15
20150064129

Wound healing composition


The invention discloses a composition comprising hyaluronic acid with a high molecular weight and povidone-iodine in low amount that has advantageous efficacy in enhancing wound healing and maintains high stability. Also disclosed is a method of using the composition of the invention in healing wounds..
Taiwan Biotech Co., Ltd.
02/26/15
20150057216

Angiotensins for treatment of fibrosis


The present invention provides, among other things, methods and compositions for treating or preventing fibrotic diseases, disorders or conditions based on angiotensin (1-7) polypeptides, and analogs or derivatives thereof. In some embodiments, compositions and methods for treating or preventing pulmonary fibrosis, pulmonary hypertension, chronic obstructive pulmonary disease (copd), asthma, cystic fibrosis, kidney fibrosis, liver fibrosis, systemic sclerosis, post-surgical adhesions, accelerating wound healing, and reducing or preventing scar formation are provided..
Tarix Pharmaceuticals Ltd.
02/19/15
20150050717

Bacteriophages expressing antimicrobial peptides and uses thereof


The present invention is generally related to engineered bacteriophages expressing antimicrobial peptides or lytic enzymes or fragments thereof for targeting a broad spectrum of bacterial hosts, and for the long-term suppression of bacterial phage resistance for reducing bacterial infections. In some embodiments, bacteriophages express antimicrobial peptides or antimicrobial polypeptides (e.g.
Trustees Of Boston University
02/19/15
20150050359

Decellularisation of tissue matrices for bladder implantation


The invention provides an improved method of producing a natural, acellular matrix scaffold for subsequent use in tissue-engineered replacement of tissues such as the bladder. Decellularisation is carried out on an expanded or distended bladder and the product retains the strength and compliance of natural material.
Tissue Regenix Limited


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Wound Healing topics: Wound Healing, Amino Acid, Amino Acid Sequence, Proliferation, Theophylline, Inflammation, Antimicrobial, Epithelial, Amino Acids, Skin Graft, Bone Healing, Vascular Disease, Skin Ulcer, Bacterial Infection, Dysfunction

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