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Wound Healing patents

      

This page is updated frequently with new Wound Healing-related patent applications.




 Wound healing compositions and treatments patent thumbnailWound healing compositions and treatments
This invention concerns improved methods, uses, and kits for treating chronic wounds through the administration of anti-connexin agents, particularly anti-connexin 43 antisense polynucleotides. The methods, uses, and kits of the invention are based on the surprising and unexpected discovery that chronic wounds that do not increase or decrease in size by more than a pre-determined amount during a pre-treatment phase are more amenable to successful treatment than wounds whose size varies outside the target range during the pre-treatment phase..
Coda Therapeutics, Inc.


 Wound healing patent thumbnailWound healing
A method of treating a chronic wound in a subject in need of such treatment is provided. The method includes administering to the subject at least one antioxidant agent in an amount effective to treat the wound.
The Regents Of The University Of California


 Pro-angiogenic peptides and peptide conjugates patent thumbnailPro-angiogenic peptides and peptide conjugates
Short bioactive sequences derived from the 2nd loop of the 7-transmembranal receptor of endothelial differentiation gene 3 (edg3) useful in stimulation of angiogenesis, and peptide conjugates comprising a permeability enhancing moiety, are provided. Also provided are pharmaceutical compositions comprising the peptides and methods of use in conditions were insufficient blood-supply occurs, or which are associated with endothelia dysfunction such as peripheral vascular diseases, coronary artery diseases, cerebrovascular diseases, diabetes and delayed wound healing, pulmonary disease, eye diseases and pathological condition related to severe infection..
Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd.


 Wet wound dressing patent thumbnailWet wound dressing
A wet wound dressing is formed from hydrophilic polyurethane foam. The hydrophilic polyurethane foam is formed by the foaming process using a hydrophilic polyurethane material and a foaming agent.
Taicend Technology Co., Ltd


 Sterilized compositions of cyanoacrylate monomers and naphthoquinone 2,3-oxides patent thumbnailSterilized compositions of cyanoacrylate monomers and naphthoquinone 2,3-oxides
Sterilized wound healing compositions comprise stabilized cyanoacrylate monomers homogenously mixed together with a naphthoquinone 2,3-oxide, including vitamin k oxides. The compositions are sterilized by irradiation, and the sterilized compositions are shelf stable such that their viscosity does not substantially increase following at least two years of shelf storage.
Adhezion Biomedical, Llc


 Thienomethylpiperazine derivatives as inhibitors of soluble epoxide hydrolase patent thumbnailThienomethylpiperazine derivatives as inhibitors of soluble epoxide hydrolase
The present invention relates to compounds of the formula (i), wherein r1, r2, r3, r4 and x have the meanings indicated in the claims. The compounds of formula i are valuable pharmacologically active compounds.
Sanofi


 Composite synthetic nanofibrous scaffolds and articles thereof patent thumbnailComposite synthetic nanofibrous scaffolds and articles thereof
A synthetic scaffold that comprises a population of nanofibers that include collagen and an anti-thrombotic glycan is provided. In addition, a method of making the synthetic scaffold is provided.
3m Innovative Properties Company


 Biomedical device patent thumbnailBiomedical device
The present invention is related to a patterned membrane comprising nanofibrillar polysaccharides, device and compositions for improving wound healing, as well as to their manufacture and use for therapy.. .
Upm-kymmene Corporation


 Patterned membrane patent thumbnailPatterned membrane
The present invention is related to a patterned membrane comprising nanofibrillar polysaccharides, device and compositions for improving wound healing, as well as to their manufacture and use for therapy.. .
Upm-kymmene Corporation


 Polyhydroxyalkanoate medical textiles and fibers patent thumbnailPolyhydroxyalkanoate medical textiles and fibers
Absorbable polyester fibers, braids, and surgical meshes with prolonged strength retention have been developed. These devices are preferably derived from biocompatible copolymers or homopolymers of 4-hydroxybutyrate.
Tepha, Inc.


Method of treating wounds

The present disclosure provides a method of treating wound healing in a subject, the method comprising administering to the subject a compound that inhibits vegf-b signalling.. .
B-creative Sweden Ab

Substituted piperidinyl-tetrahydroquinolines

The present application relates to novel substituted piperidinyltetrahydroquinolines, to processes for their preparation, to their use for the treatment and/or prevention of diseases and to their use for preparing medicaments for the treatment and/or prevention of diseases, in particular for the treatment and/or prevention of diabetic microangiopathies, diabetic ulcers on the extremities, in particular for promoting wound healing of diabetic foot ulcers, diabetic heart failure, diabetic coronary microvascular heart disorders, peripheral and cardial vascular disorders, thromboembolic disorders and ischaemias, peripheral circulatory disturbances, raynaud's phenomenon, crest syndrome, microcirculatory disturbances, intermittent claudication, and peripheral and autonomous neuropathies.. .
Bayer Pharma Aktiengesellschaft

Substituted bipiperidinyl derivatives

The invention relates to novel substituted bipiperidinyl derivatives, to processes for their preparation, to their use for the treatment and/or prevention of diseases and to their use for preparing medicaments for the treatment and/or prevention of diseases, in particular for the treatment and/or prevention of diabetic microangiopathies, diabetic ulcers on the extremities, in particular for promoting wound healing of diabetic foot ulcers, diabetic heart failure, diabetic coronary microvascular heart disorders, peripheral and cardiac vascular disorders, thromboembolic disorders and ischaemias, peripheral circulatory disturbances, raynaud's phenomenon, crest syndrome, microcirculatory disturbances, intermittent claudication, and peripheral and autonomous neuropathies.. .
Bayer Pharma Aktiengesellschaft

Multi-component electrospun fiber scaffolds

A scaffold may comprise a first polymeric electrospun fiber comprising a first material having a first degradation rate, and a second polymeric electrospun fiber comprising a second material having a second degradation rate different from the first degradation rate. The first degradation rate may substantially correspond to a cell infiltration rate, and the second degradation rate may be slower than the first degradation rate.
Nanofiber Solutions, Inc.

Composition and dressing for wound treatment

The invention provides methods and compositions for wound treatment and/or blood clot formation, e.g., arresting the flow of blood from an open wound. The methods and compositions provide for promoting and accelerating wound healing and optionally provide for inhibition of microbial infection and/or a local analgesic effect..
Protege Biomedical, Llc

Drug delivery devices and growth factor formulations for accelerated wound healing

The present invention is directed to novel drug delivery devices and pharmaceutical compositions containing growth and differentiation factor proteins. Said devices and compositions are specifically designed to accelerate tissue regeneration and wound healing processes of mammalian tissues.
Biopharm Gesellschaft Zur Biotechnologischen Entwicklung Von Pharmaka Mbh

Method for wound healing

The present invention relates generally to methods and compositions for promoting wound healing in a subject. In particular, the invention relates to the use of ingenol compounds, particularly ingenol angelates, in wound healing and compositions thereof which contain such compounds..
Leo Laboratories Limited

Methods for the synthesis of ceragenins

Disclosed herein are methods of making ceragnenin compounds for treating, preventing, or diagnosing diseases, disorders, or conditions associated with bacterial or viral infections, cancer, inflammation, and osteogenesis. Ceragenin compounds display broad-spectrum antibacterial activity utilizing a mode of action similar to antimicrobial peptides, but without the high synthesis costs and susceptibility to proteolytic degradation.
Brigham Young University

Methods for the synthesis of ceragenins

Disclosed herein are methods of making ceragnenin compounds for treating, preventing, or diagnosing diseases, disorders, or conditions associated with bacterial or viral infections, cancer, inflammation, and osteogenesis. Ceragenin compounds display broad-spectrum antibacterial activity utilizing a mode of action similar to antimicrobial peptides, but without the high synthesis costs and susceptibility to proteolytic degradation.
Brigham Young University

Infusion set adhesive systems

Improvements in an adhesive patch for an infusion set include the addition of an antiperspirant, wound healing and/or antimicrobial agent to the adhesive surface, and the layering of different backing materials to improve performance characteristics of the patch. Patches may be offered as part of a product line, in which differently shaped patches are provided for attachment to different parts of the body, and different pressure sensitive adhesives provide different peel strength according to different use patterns of the end user..
Becton, Dickinson And Company

Compositions and methods to diagnose diabetes and/or to treat negative effects of diabetes

The present disclosure describes a genome-wide transcriptional analysis of differentially expressed genes in diabetic, non-diabetic, normal and wounded tissue. The analysis allowed development of compositions and methods to diagnose diabetes and/or to treat negative effects of diabetes, including delayed wound healing and reduced vision..
Wayne State University

Tilapia piscidins for use in enhancement of wound healing

The preset invention relates to a new method for enhancing wound healing comprising administering a subject in need thereof with a therapeutically effective amount of a tilapia piscidin (tp), which is selected from the group consisting of tp1, tp2, tp3, tp4, tp5 and combination thereof. A composition or pharmaceutical composition comprising the tp are also provided..
National Taiwan Ocean University

Uses of kappa opioid synthetic peptide amides

The invention relates to methods of use of synthetic peptide amides that are ligands of the kappa opioid receptor in the treatment and prevention of kappa opioid receptor-associated diseases and conditions; and particularly to uses of these agonists in the prophylaxis, inhibition and treatment of pain, inflammation and pruritis associated with a variety of diseases, disorders and conditions. Inflammatory conditions preventable or treatable by the methods of the invention include diseases and conditions associated with elevated levels of a proinflammatory cytokines, such as tnf-α, il-1β, il-6, mmp-1 and mmp-3.
Cara Therapeutics, Inc.

Methods and compositions for regenerating and repairing damaged or aged tissue or organs using nonviable irradiated or lyophilized pluripotent stem cells

Compositions and methods are provided herein for regenerating and repairing damaged or aged tissue or organs using nonviable lethally irradiated or lyophilized pluripotent stem cells. In one aspect, the compositions and methods described herein provide anti-aging benefits to the skin by increasing the hydration reducing fine lines, wrinkles, and pores of the skin.

Methods of using regenerative cells to promote wound healing

Cells present in adipose tissue are used to promote wound healing in a patient. Methods of treating patients include processing adipose tissue to deliver a concentrated amount of regenerative cells obtained from the adipose tissue to a patient.
Cytori Therapeutics, Inc.

Methods for treatment of wound healing utilizing chemically modified oligonucleotides

The present invention relates to rnai constructs with improved tissue and cellular uptake characteristics and methods of use of these compounds in dermal and fibrotic applications. Aspects of the invention provide nucleic acid molecules for the prophylactic treatment of wounding to reduce scarring.
Rxi Pharmaceuticals Corporation

Methods of promoting wound healing using crm1 inhibitors

The invention generally relates to the use of nuclear transport modulators, e.g., crm1 inhibitors, and more particularly to a compound represented by structural formula (i) or a pharmaceutically acceptable salt thereof, wherein ring a, x, r1, r2 and n are as defined and described herein, in a method for promoting wound healing in a subject.. .
Karyopharm Therapeutics Inc.

Substituted bipiperidinyl derivatives

The invention relates to novel substituted bipiperidinyl derivatives, to processes for their preparation, to their use for the treatment and/or prevention of diseases and to their use for preparing medicaments for the treatment and/or prevention of diseases, in particular for the treatment and/or prevention of diabetic microangiopathies, diabetic ulcers on the extremities, in particular for promoting wound healing of diabetic foot ulcers, diabetic heart failure, diabetic coronary microvascular heart disorders, peripheral and cardial vascular disorders, thromboembolic disorders and ischaemias, peripheral circulatory disturbances, raynaud's phenomenon, crest syndrome, microcirculatory disturbances, intermittent claudication, and peripheral and autonomous neuropathies.. .
Bayer Pharma Aktiengesellschaft

Substituted piperidinyltetrahydroquinolines

The present application relates to novel substituted piperidinyltetrahydroquinolines, to processes for their preparation, to their use for the treatment and/or prevention of diseases and to their use for preparing medicaments for the treatment and/or prevention of diseases, in particular for the treatment and/or prevention of diabetic microangiopathies, diabetic ulcers on the extremities, in particular for promoting wound healing of diabetic foot ulcers, diabetic heart failure, diabetic coronary microvascular heart disorders, peripheral and cardial vascular disorders, thromboembolic disorders and ischaemias, peripheral circulatory disturbances, raynaud's phenomenon, crest syndrome, microcirculatory disturbances, intermittent claudication, and peripheral and autonomous neuropathies.. .
Bayer Pharma Aktiengesellschaft

Wound care dressing

A wound care dressing is provided, including a hydrophobic base fabric, a plurality of electrode pairs, a plurality of hydrogel layers, and a waterproof thin film. The hydrophobic base fabric has a first surface and a second surface opposite to each other.
Taiwan Textile Research Institute

Crosslinked human or animal tissue products and their methods of manufacture and use

Degradable bioprostheses made of collagen-based material having amine-based and ester-based crosslinks are provided, as are methods for their formation and use. Some embodiments of the present invention are directed towards a method of controlling the ratio of amine-based crosslinks to ester-based crosslinks within a collagen-based material to provide a tailorably crosslinked collagen-based material.
Harbor Medtech, Inc.

Small molecules that promote skin regeneration

Provided herein are small molecules for the induction of fibroblast proliferation and increased secretion or production of proteins. The small molecules described herein can be used for the promotion of skin regeneration.
International Stem Cell Corporation

Pharmaceutical composition comprising a ryanodine receptor antagonist for facilitating wound healing

The invention relates to the use of pharmaceutical compositions containing as the active agent a compound of formula i in the treatment of dermal wounds. The compositions may be used for the promotion of healing of wounds affecting the deeper layers under the epithelium, including dermal- and sub dermal connective tissue, being cut, punctured, sliced wounds or originating in insufficient tissue perfusion, chronic diseases or other harms.
Szegedi TudomÁ Nyegyetem

Formulation and process for modulating wound healing

R1 to r4 are independent substituents at any available position of the phenyl rings, preferably at 3, 3′, 4, 4′, and/or 5, 5′; and m, n, p, and q are independently 0, 1, 2, or 3 representing the number of substituents of the rings, respectively, but at least one of m or n must be ≧1. Each r1 to r2 is independently selected from substituents described herein, including but not limited to hydroxyl, alkoxy, halo, halomethyl and glycosides.

Integrated surface stimulation device for wound therapy and infection control

The present invention provides a thin and flexible device and method of use thereof for wound treatment and infection control. The integrated surface stimulation device may comprise a complete wireless stimulation system in a disposable and/or reusable flexible device for widespread use in multiple therapeutic applications.
Case Western Reserve University

Tissue scaffold materials for tissue regeneration and methods of making

Disclosed herein are tissue scaffold materials with microspheres of one density embedded in hydrogel of a different density. The disclosed materials have improved ability to facilitate cellular invasion and vascularization for wound healing and tissue regeneration.
Cornell University

Wound healing using topical systems and methods

The present invention generally relates to compositions and methods for topical or transdermal delivery and treatment of wounds and/or promoting wound healing. In some cases, the composition may include nitric oxide and/or peptides such as thyrotropin-releasing hormone (trh) and/or gnrh (gonadotropin-releasing hormone).
Transdermal Biotechnology, Inc.

Compositions and methods for wound healing and tissue repair

Provided are peptides that can inhibit collagen synthesis, processing and/or secretion from scar forming cells or fibroblasts. Also provided are methods for using the peptides to produce an anti-fibrotic, anti-scarring, anti-inflammatory, and/or pro-regenerative effect, e.g., on an injured or diseased tissue..
University Of South Carolina

Compositions and methods for macrophage conversion

The present invention describes methods and compositions of hydrogel microspheres for inducing macrophage conversion by sequentially converting a first population of wound macrophages in a wound to m2a macrophages by exposing the first population of wound macrophages to il-4 and converting a second population of wound macrophages to m2c macrophages by exposing the second population of wound macrophages to il-10. One aspect describes a method of inducing macrophage conversion in a wound.
Drexel University

Histatin for corneal wound healing and ocular surface disease

Histatins may be used for corneal wound healing and as a treatment for ocular surface disease in humans and other animals. For example, histatins could be included in eye drops, eye gels, ointment, glue, or embedded in (polymer) contact lenses..
Rapid Pathogen Screening, Inc.

Tissue inhibitor of metalloproteinases (timp) linked to glycosylphosphatidylinositol (gpi) - anchors for treatment of cancer and skin lesions

The present invention relates to fusion constructs of glycosylphosphatidylinositol (gpi)-anchored tissue inhibitors of metalloproteinases (timps) and their use for the treatment of cancer and in regenerative medicine. By this approach, the gpi-anchored timp proteins are incorporated into the surface membrane of tumor cells and render tumor cells sensitive to fas-induced apoptosis.

Externally-applied patient interface system and method

A surface-wound healing dressing for a wound or incision includes a slip drain located within the closed wound or incision. A wick is placed over the closed wound or incision in contact with the slip drain.
Kci Licensing, Inc.

Improved wound healing compositions and treatments

This invention concerns improved methods, uses, and kits for treating chronic wounds through the administration of anti-connexin agents, particularly anti-connexin 43 antisense polynucleotides. The methods, uses, and kits of the invention are based on the surprising and unexpected discovery that chronic wounds that do not increase or decrease in size by more than a pre-determined amount during a pre-treatment phase are more amenable to successful treatment than wounds whose size varies outside the target range during the pre-treatment phase..
Coda Therapeutics, Inc.

Collagen and micronized placental tissue compositions and methods of making and using the same

Described herein are compositions of collagen and micronized placental tissue components, methods for producing the same and methods for using the same for wound healing, repairing damaged tendons, cosmetic applications and covering biocompatible materials and/or devices.. .
Mimedx Group, Inc.

Collagen compositions and uses for biomaterial implants

Compositions containing purified collagen biomaterial derived from tissues, for example, insoluble amnion, soluble amnion, soluble chorion of the human placenta, are provided. The collagen compositions can be used to promote wound healing, promote tissue regeneration, prevent or reduce scarring, reduce local inflammation, minimize tissue rejection, promote graft integration.
Mam Holdings Of West Florida, L.l.c.

Combination treatments and compositions for wound healing

Viral vegf and viral anti-inflammatory cytokine compositions, methods of treatment using them, and kits containing them for use in the promotion and/or improvement of wound healing and/or tissue repair, and for anti-scarring, anti-inflammatory, anti-fibrosis and anti-adhesion indications.. .
Otago Innovation Limited

Dissection handpiece and reducing the appearance of cellulite

A dermatological skin treatment device is provided. The device comprises a handpiece and a cutting tool, wherein the tool is inserted through the conduit and percutaneously inserted into a tissue disposed within a recessed area of the handpiece.
Ulthera, Inc.

Three-dimensional porous film contact layer with improved wound healing

A wound dressing has a micro-architecture to produce appropriate strains in cells to promote the healing a wound. The apparatus includes a wound cover for defining a reservoir over a wound in which a negative pressure may be maintained by forming a substantially fluid-tight seal around the wound, a vacuum source in fluid communication with the reservoir and suitable for providing an appropriate negative pressure to the reservoir to stimulate healing of the wound, and a porous structure positioned in contact with the wound for delivering micro-mechanical forces to localized areas of the wound.
Smith & Nephew, Inc.

Modified nucleic acids, and acute care uses thereof

The invention provides compositions and methods for effecting wound healing in a mammal, where the compositions include therapeutic mrna which incorporate modified nucleosides and nucleotides.. .
Moderna Therapeutics, Inc.

Composite bioabsorbable barrier membranes with sustained dual drug delivery for tissue engineering and guided tissue regeneration

In this invention, composite polymeric barrier membrane is developed for clinical applications related to guided tissue regeneration and guided bone regeneration. The compositions of this polymeric membrane have conventional mechanical functions of a barrier membrane and will enable space maintenance and stabilization of the healing surgical wound.

Method for enhancing wound healing

The invention relates to a method for enhancing wound healing in a subject in need thereof, comprising administering to the subject a composition comprising fibronectin type iii domain-containing protein 5 (fndc5) or its cleaved fragment irisin in an amount effective to enhance wound healing. .
National Sun Yat-sen University

Methods of treating chronic wounds with amniotic fluid having elevated levels of tissue inhibitors of matrix metalloproteinases

Methods for treating chronic wounds with an amniotic fluid having a therapeutically effective amount of tissue inhibitors of matrix metalloproteinases (timps) are described. The amniotic fluid can be obtained from a female donor during a period of gestation when the concentration of endogenous timps are at or near their maximum level.
Liventa Bioscience, Inc.

Methods and compositions for treatment of penile defects

A composition for use in treating penile defects, including erectile dysfunction and peyronie's disease, is provided. The composition includes adipose tissue and stem cells.

Pharmaceutical composition for improving wound healing or prophylactically preventing or inhibiting scar formation

A pharmaceutical composition for improving wound healing is provided. The pharmaceutical composition includes (a) hyaluronic acid or its derivation, (b) an effective amount of an active ingredient; and optionally (c) pharmaceutically acceptable carriers and/or excipients.
Yung Shin Pharm. Ind. Co., Ltd.

Therapeutic composition for wound healing

A therapeutic composition comprising a beta-glucan, at east one fatty acid, and at least one secondary polysaccharide, which may increase a rate of wound healing. A method for healing a wound in a subject, by administering to a subject in need thereof, the therapeutic composition as described..

Modulation of mrtf-a activity in pathologic fibrosis and wound healing

The present disclosure concerns uses for isoxazole compounds or salts or analogs thereof for the treatment of wounds. The present disclosure also concerns devices for delivering a isoxazole compound or salts or an analogs thereof to a wound site..
The Board Of Regents Of The University Of Texas Sy Stem

Variable intensity laser treatments of the skin

A method for providing localized heating of the dermal layers of skin of a patient, using energy in the form of a group of pulses having defined parameters in a controlled manner. This method preferably uses an optical delivery system to deliver pulsed energy to a specific spot of skin so that targeted layers of the affected skin are heated to a desired temperature range.
Seminex Corporation

Light activated composite tissue adhesives

A light activated collagen-flavin composite layer incorporating riboflavin is applied as treatment for infected lesions. These composites have also been found to be strong tissue adhesives that are effective in closing and sealing wounds, fixation of grafts/ implants and anastomoses.
Conversion Energy Enterprises, Inc.

Skin button used for wound healing

A skin button used for wound healing is provided, which includes a one-piece formed structure with upper layer and lower layer consisting of a 1st skin button and a 2nd skin button. A through hole is provided in a junction of the 1st skin button and the 2nd skin button, which runs through the 1st skin button and the 2nd skin button, so as to form a duct connected the 1st skin button and the 2nd skin button to an outside.
Shanghai Shili International Trading Co., Ltd.

Compositions and treatments based on cadherin modulation

Anti-cadherin and anti-zo-1 agents and compositions, and kits containing them for use in the promotion and/or improvement of wound healing and/or tissue repair, and for anti-scarring, anti-inflammatory, anti-fibrosis and anti-adhesion indications.. .
Coda Therapeutics, Inc.

Integrated zwitterionic conjugated polymers for bioelectronics, biosensing, regenerative medicine, and energy applications

The present invention is directed to a versatile and high performance zwitterionic cp platform, which integrates all desired functions into one material. This zwitterionic cp consists of the conducting backbone and multifunctional zwitterionic side chains.
The University Of Akron

Antimicrobial silver hydrogel composition for the treatment of burns and wounds

An antimicrobial therapeutic hydrogel composition comprises a pharmaceutical and/or medical grade silver salt, and an aloe vera gel or extract. The composition could also include stabilizing agents, a non-ionic surfactant, polyol, and hydrophilic hygroscopic polymers.
Celacare Technologies, Llc

Methods and compositions to inhibit metastasis and to treat fibrosis and to enhance wound healing

Methods and compositions are provided for inhibiting or treating metastasis based on discoveries regarding kif19 and cep192. Methods and compositions are provided for enhancing wound healing, treating fibrosis, reducing scarring and treating nerve pain..
Albert Einstein College Of Medicine, Inc.

Light-emitting devices for wound healing

Methods and devices related to wound healing using phototherapy are described. Some embodiments provide an organic light-emitting diode device, such as a light-emitting device for phototherapy, comprising ring system 1, ring system 2, ring system 3, ring system 4 or ring system 5..
Nitto Denko Corporation

Wound cleansing apparatus

An apparatus for cleansing and promoting tissue growth in wounds, in which irrigant fluid optionally containing cell nutrients and/or other physiologically active material from a reservoir connected to a conformable wound dressing and wound exudate from the dressing are recirculated by a device for moving fluid through a flow path which passes through the dressing, a biodegradable scaffold in contact with the wound bed and a means for fluid cleansing and back to the dressing. The apparatus has means for supplying thermal energy to the fluid in the wound.
Smith & Nephew Plc

Silk/platelet composition and use thereof

The present disclosure relates generally to silk fibroin and unlysed platelet compositions. The compositions are useful for a variety of medical uses such as wound healing or repair and soft tissue repair or augmentation..
Tufts University

Cosmetic and topical compositions comprising cannabigerol

This invention discloses various cosmetics and topical formulations comprising cannabigerol, a non-psychoactive cannabinoid. The formulation may be an anti-aging cream for day or night application, a hand and nail cream, an eye cream, an acne treatment cream or tonic, an anti-diaper rash cream, a shampoo, a conditioner, a body wash, a face wash, deodorant spray, or a lip balm formulation.
Axim Biotechnologies, Inc.

Substituted dihydropyrazolones for treating cardiovascular and hematological diseases

The present application relates to novel substituted dihydropyrazolone derivatives, processes for their preparation, their use for treatment and/or prophylaxis of diseases and their use for the preparation of medicaments for treatment and/or prophylaxis of diseases, in particular cardiovascular and hematological diseases and kidney diseases, and for promoting wound healing.. .
Bayer Intellectual Property Gmbh

Wound healing promoting granulation and epithelialisation at a tissue site

An apparatus for promoting granulation and epithelialisation at a tissue site having a substantially gas impermeable, flexible mat. A plurality of projections extend from a surface of the substantially gas impermeable, flexible mat, and each projection has a first end connected to the surface and a second end opposing the first end.
Kci Licensing, Inc.

Wound healing compositions involving medicinal honey, mineral ions, and methylglyoxal, and methods of use

The invention provides compositions based on either medicinal honey containing broad spectrum antibacterial activities of peroxide, polyphenols and methylglyoxal, or an effective amount of an active anti-inflammatory ingredient of mineral solids fortified with methylglyoxal antibacterial activity, or a mixture of both for the treatment of wounds; and methods of treating a wound, comprising contacting a wound with any one of the above compositions or a wound dressing containing any one of the above compositions.. .

Silver-copper-zinc oxide wound care system

A wound care system for promoting wound healing and for preventing infections thereof and a method for producing the same includes an anti-microbial solution and a multi-layer wound dressing. The anti-microbial solution contains a mixture of colloidal silver, colloidal copper and colloidal zinc oxide mixed in sterile purified water.

Compositions comprising sulfated polysaccharides and uses thereof

The present invention relates to a composition for intravaginal and/or for internal mucosal application, comprising an effective amount of a sulfated polysaccharide, one or more of a natural quaternary polymer, a quaternary molecular compound, a metalloproteinase inhibitor, one or more anti-inflammatory agent, an acid ph control buffering system or any combination thereof, and a pharmaceutically acceptable carrier. The invention is further related to a method of treating or alleviating vaginal infection, vaginal dryness, vaginal or vulvo vaginal atrophy, vaginal itching, dyspareunia, vaginal or vulvar pain, vaginal or perivaginal inflammation or for promoting vaginal or wound healing, vaginal atrophy/dryness caused by radiotherapy, chemotherapy and/or hormonal treatment and decreased vaginal boundary lubrication or a disease or condition associated therewith or of improving vaginal boundary lubrication.
Algamed Therapeutics (a.m.t) Ltd

Induction of cellular senescence for tissue therapies

Provided are compositions and methods for aiding in healing of a tissue wound in an individual. The method generally entail delivering to an individual in need thereof senescent cells such that healing of the wound is accelerated.
Health Research, Inc.

Wound care bandage and wound healing

A wound healing system and a wound care bandage are provided. The wound care bandage has an electronics housing that houses a battery and wound care microcontroller.
Enermed, Llc

Mir-92 inhibitors and uses thereof

The present invention provides oligonucleotide inhibitors of mir-92 and methods of using said inhibitors for inhibiting the function and/or activity of mir-92 in a subject in need thereof. The present invention also provides methods for evaluating or monitoring the efficacy of a therapeutic for promoting wound healing and selecting a subject for treatment with a therapeutic that modulates mir-92 function and/or activity..
Miragen Therapeutics, Inc.

Self adhering suction port pad securement device for use with a negative pressure wound healing drape or dressing

A securement device may have a release strip, a release layer, a film having an adhesive and/or a back layer. The release strip and/or the release layer may be removable from the adhesive.
George Medical, Llc

Cross-linked platelet material

This document provides methods and materials involved in making and using cross-linked platelet material (e.g., cross-linked lysate material from human platelets such as human platelets obtained from platelet blood collection preparations or platelet apheresis preparations). For example, methods and materials for cross-linking platelet material (e.g., lysate material obtained from human platelets) to form a matrix (e.g.
Mayo Foundation For Medical Education And Research

Use of nucleic acids with reduced pressure therapy

Provided is a method of treating a wound site. Also provided is a system for treating a wound site.
Kci Licensing, Inc.

Purin derivatives for use in the treatment of fab-related diseases

The present invention relates to the finding that certain dpp-4 inhibitors are particularly suitable for wound healing preferably in diabetic patients.. .
Boehringer Ingelheim International Gmbh

Bioresorbable wound dressing

The present invention is directed to novel non-woven fabrics containing growth and differentiation factor proteins. Said fabrics are specifically designed to accelerate tissue regeneration and wound healing processes of mammalian tissues.
Carl Freudenberg Kg

Lipid nanoparticles for wound healing

The present invention refers to lipid nanoparticles comprising a growth factor and/or an antimicrobial peptide and to the method for their preparation. Moreover, it refers to pharmaceutical compositions comprising such lipid nanoparticles, and a pharmaceutical acceptable carrier.
Praxis Biopharma Research Institute

Compounds and formulations for the treatment of wounds

The present invention relates to the treatment of wounds. More particularly, it relates to compounds according to formula (1) for use in methods of promoting wound healing, to formulations which incorporate these compounds and to a method of treating wounds using such compounds and formulations: wherein r1 and r2 may be the same or different and are selected from the group consisting of hydrogen (h) and a physiologically hydrolysable chemical group consisting of alkyl, alkyl carbonyl, alkenylcarbonyl arylcarbonyl, heteroarylcarbonyl, alkoxycarbonyl, aryloxycarbonyl, heteroaryloxycarbonyl, alkylether, alkenylether, arylether, and heteroarylether groups wherein the alkyl group or moiety consists of unsubstituted or substituted, straight-chain or branched-chain and cyclic alkyl groups having 2-22 carbon atoms, wherein the alkenyl moiety consists of unsubstituted and substituted, straight-chain or branched-chain and cyclic alkenyl groups having 2-22 carbon atoms, wherein the aryl moiety consists of unsubstituted and substituted phenyl, and phenalkyl groups wherein the alkyl moiety contains 1-3 carbon atoms and the phenyl moiety is unsubstituted or substituted, and the heteroaryl moiety is an aromatic 5- or 6-membered heterocyclic ring containing one or two heteroatoms selected from the group consisting of nitrogen, oxygen, and sulphur..
Nitto Denko Corporation

Ointment containing a hydrolyzed fibroin and manufacturing same

Embodiments of the present invention provide a topical agent that is a preparation containing hydrolyzed silk. The topical agent is applied to a wound site for use in wound healing, an thus, an object thereof being to have an effect of promoting wound healing and to satisfy practical application conditions with regard to an irritative property, stability, handling ease, and the like.
Kagoshima University

Composition having a. paniculata for wound healing and skin whitening, and method by using the same

The present invention provides a pharmaceutical composition for wound healing and/or skin whitening. The pharmaceutical composition comprises active ingredient of andrographis paniculata extract and/or andrographolide and a pharmaceutical acceptable carrier.
National Dong Hua University

Wound healing electrode set

The set for the electrical stimulation of a patient, comprises a backing, at least one electrically active zone and a wire connected to said electrically active zone for connection to a stimulator. Said backing has the shape of a bandage or of a plaster..

Novel peptide having ability to synthesize collagen and use thereof

Provided are a cosmetic composition and pharmaceutical composition for wound healing capable of efficiently performing collagen synthesis in skin, wherein the compositions contain, as an active ingredient, yigsr peptide having the amino acid sequence of seq id no: 1 or a peptide derivative having a palmitoyl group added to an n-terminal of the peptide.. .

Method for isolation and purification of microvesicles from cell culture supernatants and biological fluids

The present invention relates to the fields of medicine, cell biology, molecular biology and genetics. In particular, the present invention provides methods to isolate and purify microvesicles from cell culture supernatants and biological fluids.

Methods and compositions for promoting wound healing

The present invention provides methods and compositions that use the combination of tris and edta to inhibit the growth of microorganisms at the site of a wound or burn, and/or to promote the healing of a wound or burn, and/or to reduce the sensation of pain at the site of a wound or burn. The amount of tris and edta applied to a wound or burn can be selected to achieve one or more of the foregoing effects..

Bioactive alkaloid compositions and their medical uses

The present invention relates to a novel alkaloid and novel bioactive alkaloid fractions derivable from ribes preferably selected among ribes rubrum and ribes nigrum; methods of manufacturing such bioactive ribes alkaloid fractions and their use for the inhibition of ikk-β, pde4 and/or pde5 and in addition their promoting effect on mitochondrial biogenesis and function; their therapeutic or non-therapeutic applications as nutritive or medicinal products in the management of conditions associated with impaired mitochondrial function or ikk-β, pde4 and/or pde5 activity, such as inflammation, neurodegeneration, dyslipidemia, type 2 diabetes mellitus, impaired wound healing, sarcopenia and other conditions associated with muscle dysfunction or tiredness and fatigue, or where optimization of muscular or cognitive function is desired; extracts, juices or concentrates of ribes comprising such alkaloids; compositions comprising such alkaloids, including pharmaceutical compositions, nutritive product such as functional foods and nutraceutical compositions, and cosmetic compositions and medical devices.. .

Method for wound infection prevention

A wound healing device and method that greatly reduces the risk of infection of an incision or wound by removing fluid from the subcutaneous layers of the skin. The wound healing device includes a first portion that is positioned external of, and on top of, the wound.

Apparatus for wound infection prevention

A wound healing device and method that greatly reduces the risk of infection of an incision or wound by removing fluid from the subcutaneous layers of the skin. The wound healing device includes a first portion that is positioned external of, and on top of, the wound.

Method and improved wound healing

A pad for electrically stimulated wound healing, including a pad configured to be placed on a wound, at least one anode disposed on the pad to contact the wound, and at least one cathode disposed on the pad to contact the wound, the at least one cathode being disposed separately from the at least on anode. The pad wherein the at least one anode and the at least one cathode in contact with the wound provide a flow of electrical current in an intended direction through the wound based on the separate locations of the at least one anode and the at least one cathode..

Combination therapy to promote wound healing

Methods for increasing and/or promoting wound healing, wound re-epithelialization and dermal regeneration of epithelial tissues and cutaneous wounds by administration to a subject of an extracellular matrix scaffold or scaffold for dermal regeneration (sdr) populated with beta adrenergic receptor antagonist pre-conditioned mesenchymal stem cells (mscs) are provided. Compositions and kits comprising an extracellular matrix scaffold (ecms) populated with beta adrenergic receptor antagonist pre-conditioned mesenchymal stem cells (mscs) are also provided..

Polymers and methods thereof for wound healing

Wherein y is 1 or more. Other embodiments of the invention provide a therapeutic method for treating a wound in an animal comprising administering to an animal in need of such therapy, an effective amount of a copolymer as described herein..

Method for wound infection prevention

A wound healing device and method that greatly reduces the risk of infection of an incision or wound by removing fluid from the subcutaneous layers of the skin. The wound healing device includes a first portion that is positioned external of, and on top of, the wound.

Pendant hydrophile bearing biodegradable compositions and related devices

A composition comprising at least one polymer having the structure a-b-a′, wherein a and a′ may be the same or different and each is a degradable polyester component and wherein b is the reaction product resulting from the reaction between a diol, having one or more pendant oligomeric or polymeric groups, and a and a′. Additionally, a bioresorbable patch comprising: (a) an adhesion barrier component comprising the composition in the form of a film; and (b) an adhesive component comprising (i) at least one synthetic adhesive polymer and/or (ii) at least one polysaccharide.
Dsm Ip Assets B.v.

Synthetic microfluidic systems for wound healing

A method of assaying wound healing can include: growing cells on the matrix in the first flow channel; introducing an agent that removes the matrix from the junction; introducing a matrix material into the second flow channel so as to form the second matrix in the second flow channel and junction; and detecting cellular migration into the junction onto the second matrix. The agent that removes the matrix can include a biomolecule or chemical agent.
Cfd Research Corporation

Formulations comprising antisense nucleotides to connexins

A therapeutic and/or cosmetic formulation comprising at least one anti-sense polynucleotide to a connexin protein together with a pharmaceutically acceptable carrier or vehicle is useful in site specific down regulation of connexin protein expression, particularly in reduction of neuronal cells death, wound healing, reduction of inflammation, decrease of scar formation and skin rejuvenation and thickening.. .
Coda Therapeutics, Inc.

Protein biomaterials and biocoacervates and methods of making and using thereof

The present invention relates to protein biocoacervates and biomaterials and the methods of making and using protein biocoacervates and biomaterials. More specifically the present invention relates to protein biocoacervates and biomaterials that may be utilized for various medical applications including, but not limited to, drug delivery devices for the controlled release of pharmacologically active agents, coated medical devices (e.g.
Gel-del Technologies, Inc.

A wound dressing

The present invention relates to an impregnated wound dressing having an outer membrane overlay layer and to a method of production thereof. In particular the dressing comprises a core layer that has been impregnated with a wound healing agent, such as honey, and an outer membrane overlay layer..
Manukamed Limited

Wound healing using topical systems and methods

The present invention generally relates to compositions and methods for topical or transdermal delivery and treatment of wounds and/or promoting wound healing. In some cases, the composition may include nitric oxide and/or peptides.
Transdermal Biotechnology, Inc.

Laser assisted wound healing protocol and system

A method of treating gum disease while healing the wound in the periodontium using a soft tissue diode laser which generates a beam of light having a wavelength in the visible portion of the electromagnetic spectrum (400 nm-700 nm) at a laser power of 0.001 to 1.2 watts, used with intermittent stops to control tissue temperature and biostimulate the periodontium to regenerate and heal its wound when used with substrates, the method comprising: placing the tip of the laser inside the sulcus; penetrating the entire sulcus by moving the laser light circumferentially around the tooth vertically and horizontally throughout the sulcus with intermittent stops to control tissue temperature and placing substrates in the sulcus prior to blood clot formation; followed by rf treatment of the sulcus by placing the rf headpiece tips perpendicular to the sulcus to receive rf current which further penetrates the wound site.. .
Bioregentech

Negative pressure wound dressing

A negative pressure wound dressing is provided. The negative pressure wound dressing sequentially includes a backing layer, a water blocking layer, an absorbent layer and a wound contacting layer.
Benq Materials Corporation



Wound Healing topics:
  • Wound Healing
  • Amino Acid
  • Amino Acid Sequence
  • Proliferation
  • Theophylline
  • Inflammation
  • Antimicrobial
  • Epithelial
  • Amino Acids
  • Skin Graft
  • Bone Healing
  • Vascular Disease
  • Skin Ulcer
  • Bacterial Infection
  • Dysfunction


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