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Vasocon

Vasocon-related patent applications - as published by the U.S. Patent and Trademark Office (USPTO).


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Treatment systems processes and devices addressing cerebral vasospasm/vasoconstriction
March 30, 2017 - N°20170086992

Endovascular treatment of, for example, delayed cerebral vasospasm involves the placing of a microcatheter in the affected vessels followed by the teachings of the instant disclosure, which is clinically improved with comparison to slow infusion of a vasodilating compound. Systems, processes and self-expanding designed stents and stent-like members are featured and highlighted. The stents and stent-like members being retrieved, nothing ...
Control of blood vessel physiology to treat skin disorders
Biochemics, Inc.
August 18, 2016 - N°20160235846

In a method for treating an affected skin region of a patient having a skin disorder, a vasodilation composition is applied to an affected skin region of a patient, the affected skin region exhibiting a skin disorder characterized by at least one abnormal blood vessel, and the affected skin region is then treated so as to non-invasively disrupt tissue architecture, ...
Arthroscopic irrigation solution and method for peripheral vasoconstriction and inhibition of pain and inflammation
Biochemics, Inc.
June 30, 2016 - N°20160184272

A method and solution for perioperatively inhibiting a variety of pain and inflammation processes during arthroscopic procedures. The solution preferably includes a vasoconstrictor that demonstrates substantial agonist activity at alpha adrenergic receptors and that is selected for peripheral (local) vasoconstriction and one or more additional pain and inflammation inhibitory agents at dilute concentration in a physiologic carrier, such as saline ...
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Non-flushing niacin analogues, and methods of use thereof
Trustees Of Tufts College
June 02, 2016 - N°20160151343

One aspect of the present invention relates to substituted pyridines and pharmaceutically acceptable salts thereof that are active against a range of mammalian maladies. Another aspect of the invention relates to a pharmaceutical composition, comprising a compound of the present invention or a pharmaceutically acceptable salt thereof; and a pharmaceutically acceptable excipient. The present invention also relates to methods of ...
Methods for treating pulmonary hypertension
The Medicines Company
May 19, 2016 - N°20160136196

The present invention relates to methods for treating or preventing pulmonary hypertension, reducing mortality in a subject experiencing pulmonary hypertension, or inhibiting adp-mediated vasoconstriction of pulmonary arteries in a subject, comprising administering to the subject an effective amount of a pharmaceutical composition comprising a reversible p2y12 receptor antagonist. Also provided are related medicaments, pharmaceutical compositions, and methods for preparing ...
Composition and method for treating nosebleeds
Binyarco, Llc
May 12, 2016 - N°20160128970

A composition and method for treating nosebleed, that is, epistaxis. The composition comprises bismuth subgallate and a vasoconstriction agent, preferably oxymetazoline. The composition is preferably a paste administered intranasally.
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Therapeutic suit
Omeros Corporation
April 28, 2016 - N°20160113812

The therapeutic suit reliefs joint pain by applying heat or cold relief to one or all joints of the body and bringing healing to joints by vasoconstriction, centralizing oxygenated blood around the joints during cold therapy treatment.
Method and system for providing an early risk recognition monitoring
Medieta Oy
March 24, 2016 - N°20160081628

A system for providing an early risk recognition monitoring by measurement of a peripheral tissue perfusion of a patient instead of clinically significant changes in systemic blood pressure and/or blood flow comprises a wristband device for gathering measurement data of the patient. The device measures a first temperature (t1) of the patient at the first wrist (or distal antebrachium) ...
Arthroscopic irrigation solution and method for peripheral vasoconstriction and inhibition of pain and inflammation
Omeros Corporation
March 10, 2016 - N°20160067219

A method and solution for perioperatively inhibiting a variety of pain and inflammation processes during arthroscopic procedures. The solution preferably includes a vasoconstrictor that exhibits alpha-adrenergic activity and one or more additional pain and inflammation inhibitory agents at dilute concentration in a physiologic carrier, such as saline or lactated ringer's solution. The solution is applied by continuous irrigation of a ...
Salvinorin compositions and uses thereof
The Trustees Of The University Of Pennsylvania
December 24, 2015 - N°20150366840

The invention relates to salvinorin compositions and uses thereof. Specifically, the invention relates to administering salvinorin compositions to treat diseases and disorders associated with vasoconstriction, vaso-occlusion, or disruption of blood flow and autoregulation. For example, salvinorin compositions may be administered to subjects with cardiac arrest, subarachnoid hemorrhage, stroke, cerebral vascular spasm, cerebral hypoxia/ischemia, cerebral artery occlusion, or any condition ...
Composition for prevention of vasoactivity in the treatment of blood loss and anemia
The Trustees Of The University Of Pennsylvania
October 15, 2015 - N°20150290213

The present invention relates to the prevention of cardiovascular and central nervous system side effects in mammals who receive transfusions of hemoglobin based oxygen carriers (hboc) or stored blood products containing a concentration of hemoglobin sufficient to induce vasoconstriction, by adding a vasoactivity reducing effective amount of one or more phosphodiesterase inhibitors in combination with a calcium channel blocker and/...
Cyanocobalamin, methylcobalamin, and/or adenosylcobalamin to help maintain a pain-free head and pain-free body and ...
The Trustees Of The University Of Pennsylvania
July 02, 2015 - N°20150182548

The current invention discloses novel approaches to help individuals defend against headaches and body pains with orally-delivered cyanocobalamin, methylcobalamin, adenosylcobalamin, and combinations thereof. Original clinical research conducted by the inventor on almost 2,000 humans yielded surprising and unexpected results showing differences in the frequency and severity of pains in the head and the body favoring cyanocobalamin patients over placebo. In one ...
No/nitrogen gaseous mixture with a high no content for the treatment of severe hypoxemic ...
Air Liquidee Sante (international)
May 07, 2015 - N°20150125552

The invention concerns a gaseous medicine comprising a mixture of nitrogen monoxide (no) and nitrogen (n2) for use by inhalation for the treatment of hypoxemic respiratory failure linked to pulmonary vasoconstriction in humans, said gaseous mixture containing between 1200 and 4500 ppm by volume (ppmv) of nitrogen monoxide (no) and said hypoxemic respiratory failure being chosen from acute respiratory distress syndrome (ards) ...
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Monitoring cardiovascular conditions using signal transit times
Edwards Lifesciences Corporation
April 16, 2015 - N°20150105634

Methods for monitoring cardiovascular conditions, i. E., hyperdynamic circulation, vasodilation, vasoconstriction, or central-to-peripheral arterial pressure decoupling conditions are described. These methods involve measuring a central signal proportional to or a function of the subject's heart activity and a peripheral signal proportional to or a function of a signal related to the central signal. Then calculating a time difference between features ...
Non-flushing niacin analogues, and methods of use thereof
Trustees Of Tufts College
April 09, 2015 - N°20150099787

One aspect of the present invention relates to substituted pyridines and pharmaceutially acceptable salts thereof that are active against a range of mammalian maladies. Another aspect of the invention relates to a pharmaceutical composition, comprising a compound of the present invention or a pharmaceutically acceptable salt thereof; and a pharmaceutically acceptable excipient. The present invention also relates to methods of ...
Method for producing no/n2 gaseous mixtures intended for the medical field
Air Liquide Santé (international)
December 18, 2014 - N°20140370125

The invention relates to a method for producing an no/n2 gaseous mixture, comprising the steps of effecting a purification of impure gaseous nitrogen containing impurities at least of the o2 type by putting the impure nitrogen in contact with a catalyst and then with a molecular sieve; mixing the pure nitrogen obtained with nitric oxide (no), and obtaining a ...
Thermal grill for body cooling and driver alertness
Air Liquide Santé (international)
November 20, 2014 - N°20140343798

A system for keeping a driver alert by employing a thermal grill that includes warm and cool regions. The system includes an alert module that configures the thermal grill to a heat sink configuration and a heat source configuration. The thermal grill in the heat sink configuration extracts heat from the driver's body, lowers the driver's temperature, and keeps the ...
Novel hemostatic patch and uses thereof
Air Liquide Santé (international)
October 30, 2014 - N°20140322341

Disclosed herein is a novel hemostatic patch that may be used to control and/or arrest bleeding in patients. The patch offers an effective but also minimally invasive way to control and/or arrest bleeding in a patient. The patch comprises a mucoadhesive and a compound that causes vasoconstriction. In a preferred aspect, the patch comprises chitosan and neuropeptide y. ...
Implantable device with responsive vascular and cardiac controllers
Air Liquide Santé (international)
October 23, 2014 - N°20140316480

Exemplary methods are described for providing responsive vascular control with or without cardiac pacing. An implantable device with responsive vascular and cardiac controllers interprets physiological conditions and responds with an appropriate degree of vascular therapy applied as electrical pulses to a sympathetic nerve. In one implementation, an implantable device is programmed to deliver the vascular therapy in response to low ...
Modulators of the g protein-coupled mas receptor and the treatment of disorders related thereto
Air Liquide Santé (international)
October 16, 2014 - N°20140309192

That are useful in methods of treatment and alleviation of diseases and disorders of the heart, brain, kidney, immune, and reproductive system resulting from ischemia, or reperfusion subsequent to ischemia, and any downstream complication(s) related thereto. The present invention further relates to methods of treatment and alleviation of diseases and disorders of the vasculature resulting from vasoconstriction or hypertension ...
Closed loop chronic electroacupuncture system using changes in body temperature or impedance
Air Liquide Santé (international)
July 31, 2014 - N°20140214134

A closed loop electroacupuncture (ea) system monitors any change in sympathetic drive within the body of a patient undergoing ea stimulation. The sensed change in sympathetic drive is then used to adjust at least one parameter of the ea stimulation regimen in an appropriate manner that assists regulation of the patient's autonomic nervous system (ans). One manner of determining an ...
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