Vascular Diseases

Vascular Diseases-related patent applications - as published by the U.S. Patent and Trademark Office (USPTO).

Image View List View Download All PDFs Archive

loading
NEW Diazepane derivatives and uses thereof
May 25, 2017 - N°20170145023

The present disclosure provides compounds of formula (i), and pharmaceutically compositions thereof. Compounds of formula (i) have been found to bind bromodomains and/or bromodomain-containing proteins (e. G., bromo and extra terminal (bet) proteins). Also provided are methods, uses, and kits of the compounds and pharmaceutical compositions for inhibiting the activity (e. G., increased activity) of bromodomains and/or bromodomain-containing ...
NEW Dihydropteridinone derivatives and uses thereof
May 25, 2017 - N°20170145013

The present disclosure provides compounds of formula (i), and pharmaceutically compositions thereof. Compounds of formula (i) have been found to bind bromodomains and/or bromodomain-containing proteins (e. G., bromo and extra terminal (bet) proteins). Also provided are methods, uses, and kits of the compounds and pharmaceutical compositions for inhibiting the activity (e. G., increased activity) of bromodomains and/or bromodomain-containing ...
NEW Implantable neurostimulator with integral hermetic electronic enclosure, circuit substrate, monolythic feed-through, lead assembly and anchoring ...
May 25, 2017 - N°20170143959

An implantable medical device is provided for the suppression or prevention of pain, movement disorders, epilepsy, cerebrovascular diseases, autoimmune diseases, sleep disorders, autonomic disorders, abnormal metabolic states, disorders of the muscular system, and neuropsychiatric disorders in a patient. The implantable medical device can be a neurostimulator configured to be implanted on or near a cranial nerve to treat headache or ...
Vascular Diseases Patent Pack
Download 120+ patent application PDFs
Vascular Diseases Patent Applications
Download 120+ Vascular Diseases-related PDFs
For professional research & prior art discovery
inventor
  • 120+ full patent PDF documents of Vascular Diseases-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
Heterocyclic compounds as pi3k-y inhibitors
Unist(ulsan National Institute Of Science And Techology)
May 11, 2017 - N°20170129899

Or pharmaceutically acceptable salts or stereoisomers thereof, which are inhibitors of pi3k-γ which are useful for the treatment of disorders such as autoimmune diseases, cancer, cardiovascular diseases, and neurodegenerative diseases.
Pharmaceutical composition for treating cardio-cerebrovascular diseases and method for preparing the same
Unist(ulsan National Institute Of Science And Techology)
May 11, 2017 - N°20170128514

A pharmaceutical composition, including, parts by weight of: 100-170 of a ginkgo flavone, 40-100 of a jujube extract, 100-200 of an extract of a peel of trichosanthes kirilowii, 30-60 of a saponin of codonopsis, 50-100 of a saponin of american ginseng, 40-70 of a saponin of radix astragalu, 20-50 of hirudin, 3-10 of a coenzyme q10, 40-100 of a longan ...
Methods of treating cardiovascular diseases and predicting the efficacy of exercise therapy
Critical Care Diagnostics, Inc.
May 04, 2017 - N°20170122942

Methods of treating a subject having a cardiovascular disease, selecting a therapy for a subject having a cardiovascular disease, identifying a subject having a cardiovascular disease that will benefit or not benefit from exercise therapy, determining whether a subject having a cardiovascular disease should begin, continue, not begin, discontinue, or avoid exercise therapy, determining whether a subject having a cardiovascular ...
Vascular Diseases Patent Pack
Download 120+ patent application PDFs
Vascular Diseases Patent Applications
Download 120+ Vascular Diseases-related PDFs
For professional research & prior art discovery
inventor
  • 120+ full patent PDF documents of Vascular Diseases-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
Homogeneous formulation comprising omega-3 polyunsatured fatty acid and resveratrol for oral administration
Sigma-tau Industrie Farmaceutiche Riunite S.p.a.
May 04, 2017 - N°20170119720

The present invention relates to homogeneous formulations comprising omega-3 polyunsaturated fatty acids (n-3 pufa) and resveratrol for oral administration, in which the resveratrol is solubilized in a solvent system consisting of omega-3 polyunsaturated fatty acids (n-3 pufa), or their alkyl esters, and a ionic emulsifier. The composition according to the present invention can be formulated as food or nutritional supplement ...
Benzimidazole derivatives as pi3 kinase inhibitors
Glaxosmithkline Llc
April 27, 2017 - N°20170112844

This invention relates to the use of benzimidazole derivatives for the modulation, notably the inhibition of the activity or function of the phosphoinositide 3′ oh kinase family (hereinafter pi3 kinases), suitably, pi3kα, pi3kδ, pi3kβ, and/or pi3kγ. Suitably, the present invention relates to the use of benzimidazoles in ...
Solid formulations containing omega-3 and resveratrol
Sigma-tau Industrie Farmaceutiche Riunite S.p.a.
April 27, 2017 - N°20170112791

The present application relates to invention a solid composition comprising omega-3 polyunsaturated fatty acids (n-3 pufa), or their alkyl esters, and resveratrol, adsorbed on an inert substrate and wherein the recovery of omega-3 is at least 96% after 6 months at 25° c. The composition according to the present invention can be formulated as food supplement or medicament for preventing or treating ...
Venous insufficiency treatment method
Angiodynamics, Inc.
April 20, 2017 - N°20170106167

The method of treating varicose veins and other vascular diseases provides sclerosant fluid through a catheter into the body vessel to be treated. The catheter has a lumen and a plurality of sidewall exits. The sclerosant fluid is provided under sufficient pressure so that it comes out of each exit as a jet of fluid with sufficient velocity to impinge ...
Indolin-2-one or pyrrolo-pyridin-2-one derivatives
Angiodynamics, Inc.
April 13, 2017 - N°20170101409

The compounds may be used in the treatment of cns diseases related to positive (psychosis) and negative symptoms of schizophrenia, substance abuse, alcohol and drug addiction, obsessive-compulsive disorders, cognitive impairment, bipolar disorders, mood disorders, major depression, treatment resistant depression, anxiety disorders, alzheimer's disease, autism, parkinson's disease, chronic pain, borderline personality disorder, neurodegenerative disease, sleep disturbances, chronic fatigue syndrome, stiffness, inflammatory ...
Composition comprising bio compound for treating cardiovascular disease
Chonnam National University Hospital
April 13, 2017 - N°20170100372

A pharmaceutical composition and a method for preventing or treating a cardiovascular disease are provided. The pharmaceutical composition includes a bio compound ((2′z,3′e)-6-bromoindirubin-3′-oxime) or a pharmaceutically acceptable salt thereof as an active ingredient. The pharmaceutical composition can specifically act on different types of cells constituting heart tissues, that is, can induce the growth ...
Ultra-low fractional area coverage flow diverter for treating aneurysms and vascular diseases
The Regents Of The University Of California
April 06, 2017 - N°20170095357

The various embodiments described herein include methods for fabricating thin- film flow diversion apparatuses. In one aspect, a method includes: (1) creating a plurality of trenches using photolithography and deep reactive ion etching on a substrate; (2) depositing a metal sacrificial layer on the substrate; (3) forming a nitinol layer with a plurality of fenestrations by depositing nitinol on the metal sacrificial layer; (4) ...
Vascular Diseases Patent Pack
Download 120+ patent application PDFs
Vascular Diseases Patent Applications
Download 120+ Vascular Diseases-related PDFs
For professional research & prior art discovery
inventor
  • 120+ full patent PDF documents of Vascular Diseases-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
Compositions and methods for the treatment of atherosclerotic cardiovascular diseases with pde4 modulators
Celgene Corporation
March 30, 2017 - N°20170087129

Provided herein are methods of treating, preventing or managing atherosclerosis by administering a pde4 modulator. Pharmaceutical compositions, dosage forms, and kits suitable for use in methods are also provided.
Heterocyclyl-butanamide derivatives
Celgene Corporation
March 16, 2017 - N°20170073347

In which w, x and y have the meanings indicated in claim 1, are inhibitors of tankyrase, and can be employed, inter alia, for the treatment of diseases such as cancer, cardiovascular diseases, central nervous system injury and different forms of inflammation.
Beta- and gamma-amino-isoquinoline amide compounds and substituted benzamide compounds
Aerie Pharmaceuticals, Inc.
March 16, 2017 - N°20170073325

Disclosed are beta and gamma-amino isoquinoline amide compounds and substituted benzamide compounds. In particular, the invention provides compounds that affect the function of kinases in a cell and that are useful as therapeutic agents or with therapeutic agents. The compounds of the invention are useful in the treatment of a variety of diseases and conditions including eye diseases such as ...
Bioengineered allogeneic valve
Novahep Ab
March 16, 2017 - N°20170071738

The present disclosure relates to methods for recellularization of valves in valve-bearing veins. This method is useful for producing an allogeneic venous valve, wherein a donor valve-bearing vein is decellularized and then recelluiarized using whole blood or bone marrow stem cells. The allogeneic valves produced by the methods disclosed herein are advantageous for implantation, transplantation, or grafting into patients with ...
Aplnr modulators and uses thereof
Regeneron Pharmaceuticals, Inc.
March 02, 2017 - N°20170058028

The present invention provides apelin receptor (aplnr) modulators that bind to aplnr and methods of using the same. The invention includes aplnr modulators such as antibodies, or antigen-binding fragments thereof, that inhibit or attenuate aplnr-mediated signaling. The invention includes aplnr modulators such as antibodies, or antibody fusion proteins thereof, that activate aplnr-mediated signaling. According to certain embodiments of the invention, ...
Enantiomers of the n-(2-amino-5-fluoro-2-methylpentyl)-8-[(2,6-difluorobenzyl)oxy]-2-methylimidazo[1,2-a]pyridine-3...
Bayer Pharma Aktiengesellschaft
March 02, 2017 - N°20170057958

The present application relates to novel 6-hydrogen-substituted imidazo[1,2-a]pyridine-3-carboxamides, to processes for preparation thereof, to the use thereof, alone or in combinations, for treatment and/or prophylaxis of diseases, and to the use thereof for production of medicaments for treatment and/or prophylaxis of diseases, especially for treatment and/or prophylaxis of cardiovascular disorders.
Imidazo[1,2-a]pyridines as stimulators of soluble guanylate cyclase for treating cardiovascular diseases
Bayer Pharma Aktiengesellschaft
February 23, 2017 - N°20170050962

The present application relates to novel heterocyclyl- and heteroaryl-substituted imidazo[1,2-a]pyridines, to processes for preparation thereof, to the use thereof, alone or in combinations, for the treatment and/or prophylaxis of diseases, and to the use thereof for production of medicaments for the treatment and/or prophylaxis of diseases, especially for the treatment and/or prophylaxis of cardiovascular disorders.
Imidazo[1,2-a]pyridines as soluble guanylate cyclase stimulators for the treatment of cardiovascular diseases
Bayer Pharma Aktiengesellschaft
February 23, 2017 - N°20170050961

The present application relates to novel substituted imidazo[1,2-a]pyridine-3-carboxamides, to processes for preparation thereof, to the use thereof, alone or in combinations, for treatment and/or prophylaxis of diseases, and to the use thereof for production of medicaments for treatment and/or prophylaxis of diseases, especially for treatment and/or prophylaxis of cardiovascular disorders.