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Vascular Disease

Vascular Disease-related patent applications - as published by the U.S. Patent and Trademark Office (USPTO).


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NEW Methods and apparatus for creating particle derivatives of hdl with reduced lipid content
Hdl Therapeutics
June 22, 2017 - N°20170174747

The present invention is directed to systems, apparatus and methods for creating derivatives of at least one form of hdl without substantially affecting ldl. These derivatives of hdl are particles with reduced lipid content, particularly reduced cholesterol content. These particles have the capacity to bind cholesterol and are administered to a patient to enhance cellular cholesterol efflux and reduce cholesterol ...
NEW Fumarate-co-releasing molecule hybrids, their use in the treatment of inflammatory or cardiovascular diseases and their ...
Institut National De La Sante Et De La Recherche Medicale (inserm)
June 22, 2017 - N°20170174716

The present invention relates to hybrid fumarate-co-releasing molecules capable of increasing heme oxygenase-1 (ho-1) activity and ho-1 protein expression and simultaneously releasing co, their synthesis and their use in therapeutic applications, in particular their use in the treatment of inflammatory or cardiovascular diseases.
NEW Apoptosis signal-regulating kinase inhibitors
Institut National De La Sante Et De La Recherche Medicale (inserm)
June 22, 2017 - N°20170173031

Wherein variables are as defined above. The compounds have apoptosis signal-regulating kinase (“ask1”) inhibitory activity, and are thus useful in the treatment of ask1-mediated conditions, including autoimmune disorders, inflammatory diseases, cardiovascular diseases, diabetes, diabetic nephropathy, cardio-renal diseases, including kidney disease, fibrotic diseases, respiratory diseases, copd, idiopathic pulmonary fibrosis, acute lung injury, acute and chronic liver ...
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Vascular Disease Patent Applications
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  • 215+ full patent PDF documents of Vascular Disease-related inventions.
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Use of beta-nicotinamide mononucleotide in preparation of drugs for preventing and treating arteriosclerosis and cardio-cerebrovascular ...
Bontac Bio-engineering (shenzhen) Co., Ltd.
June 15, 2017 - N°20170165282

A medication having nicotinamide mononucleotide as the active ingredient, and the use of nicotinamide mononucleotide in preparing medications for the prevention and treatment of arteriosclerosis and cardiovascular and cerebrovascular diseases caused by arteriosclerosis.
Compositions comprising statins, biguanides and further agents for reducing cardiometabolic risk
Elcelyx Therapeutics, Inc.
June 15, 2017 - N°20170165209

Compositions and methods comprising at least one biguanide compound and at least one statin combined with at least one additional active agent in fixed dose combinations are provided for reducing cardiometabolic risk, and for the treatment of cardiovascular disease, wherein the biguanide compound is formulated for delayed release.
Automatic three-dimensional segmentation method for oct and doppler oct angiography
The Regents Of The University Of California
June 15, 2017 - N°20170164825

A three-dimensional (three dimensional) segmentation method with intensity-based doppler variance (ibdv) based on swept-source oct. The automatic three dimensional segmentation method is used to obtain seven surfaces of intra-retinal layers. The microvascular network of the retina, which is acquired by the ibdv method, can be divided into six layers. The microvascular network of the six individual layers are visualized, and ...
Vascular Disease Patent Pack
Download 215+ patent application PDFs
Vascular Disease Patent Applications
Download 215+ Vascular Disease-related PDFs
For professional research & prior art discovery
inventor
  • 215+ full patent PDF documents of Vascular Disease-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
Novel indene derivative, preparation method for same, and pharmaceutical composition, for preventing or treating retinal ...
The Industry & Academic Cooperation In Chungnam National University (iac)
June 01, 2017 - N°20170152268

The present invention relates to a novel indene derivative, a preparation method for the same, and a pharmaceutical composition for preventing or treating retinal disease comprising the same as an active ingredient. The novel indene derivative of the present invention, the optical isomer of the same, or the pharmaceutically acceptable salts of the same have excellent inhibitory efficiency of receptor-interacting ...
Benzimidazole compounds and their application in cardiovascular diseases
National Taiwan University
June 01, 2017 - N°20170152245

The present invention provides substituted benzimidazoles, pharmaceutical composition comprising the substituted benzimidazoles, and their use for preventing or treating a subject suffering from diseases or conditions associated with platelet activation aggregation and/or platelet activation.
Diazepane derivatives and uses thereof
National Taiwan University
May 25, 2017 - N°20170145023

The present disclosure provides compounds of formula (i), and pharmaceutically compositions thereof. Compounds of formula (i) have been found to bind bromodomains and/or bromodomain-containing proteins (e. G., bromo and extra terminal (bet) proteins). Also provided are methods, uses, and kits of the compounds and pharmaceutical compositions for inhibiting the activity (e. G., increased activity) of bromodomains and/or bromodomain-containing ...
Dihydropteridinone derivatives and uses thereof
National Taiwan University
May 25, 2017 - N°20170145013

The present disclosure provides compounds of formula (i), and pharmaceutically compositions thereof. Compounds of formula (i) have been found to bind bromodomains and/or bromodomain-containing proteins (e. G., bromo and extra terminal (bet) proteins). Also provided are methods, uses, and kits of the compounds and pharmaceutical compositions for inhibiting the activity (e. G., increased activity) of bromodomains and/or bromodomain-containing ...
Modulators of the relaxin receptor 1
National Taiwan University
May 25, 2017 - N°20170144984

Disclosed are modulators of the human relaxin receptor 1, for example, of formula (i), wherein a, r1, and r2 are as defined herein, that are useful in treating mammalian relaxin receptor 1 mediated facets of human health, e. G., cardiovascular disease. Also disclosed is a composition comprising a pharmaceutically suitable carrier and at least one compound of the disclosure, and a method ...
Implantable neurostimulator with integral hermetic electronic enclosure, circuit substrate, monolythic feed-through, lead assembly and anchoring ...
National Taiwan University
May 25, 2017 - N°20170143959

An implantable medical device is provided for the suppression or prevention of pain, movement disorders, epilepsy, cerebrovascular diseases, autoimmune diseases, sleep disorders, autonomic disorders, abnormal metabolic states, disorders of the muscular system, and neuropsychiatric disorders in a patient. The implantable medical device can be a neurostimulator configured to be implanted on or near a cranial nerve to treat headache or ...
Multi-tyrosine kinase inhibitors derivatives and methods of use
National Taiwan University
May 25, 2017 - N°20170143688

The present invention is directed to multi-tyrosine kinase inhibitor compounds. The present invention is further directed to compositions comprising those compounds. Finally, the present invention is directed to methods of treating eye conditions including, but not limited to, diabetic background retinopathy, diabetic macular edema, diabetic proliferative retinopathy, diabetic macular edema with proliferative retinopathy, proliferative fibrovascular disease, diabetic macular edema with ...
Vascular Disease Patent Pack
Download 215+ patent application PDFs
Vascular Disease Patent Applications
Download 215+ Vascular Disease-related PDFs
For professional research & prior art discovery
inventor
  • 215+ full patent PDF documents of Vascular Disease-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
Compositions and methods for treating cardiovascular disease and myocardial infarction with dipeptidyl peptidase inhibitors or ...
Alere San Diego, Inc.
May 18, 2017 - N°20170138932

The present invention describes compositions and methods for treating cardiovascular disease and myocardial infarction using dipeptidyl peptidase inhibitors. Also provided are methods for increasing natriuretic peptide function by administering one or more analogues of b type natriuretic peptide that provide increased stability in the presence of prolyl-specific dipeptidyl peptidases.
Organic compositions to treat apoc3-related diseases
Arrowhead Pharmaceuticals, Inc.
May 18, 2017 - N°20170137814

The present disclosure relates to compositions and methods for treating apoc3-related diseases such as: hypertriglyceridemia (e. G., type v hypertriglyceridemia), abnormal lipid metabolism, abnormal cholesterol metabolism, atherosclerosis, hyperlipidemia, diabetes, including type 2 diabetes, obesity, cardiovascular disease, and coronary artery disease, among other disorders relating to abnormal metabolism or otherwise, using a therapeutically effective amount of a rnai agent to apoc3.
Vaccines and monoclonal antibodies targeting truncated variants of osteopontin and uses thereof
Affiris Ag
May 18, 2017 - N°20170137509

The present invention provides monoclonal antibodies specific for one or more truncated variants of human osteopontin and vaccines comprising at least one isolated osteopontin peptide, as well methods for manufacturing said antibodies and vaccines. Furthermore, a diagnostic method making use of said antibodies is provided. Said antibodies and vaccines are used in therapy, especially in treatment and/or prevention of ...
Composition for inducing direct transdifferentiation of somatic cell into vascular progenitor cell, and use thereof
Unist(ulsan National Institute Of Science And Techology)
May 11, 2017 - N°20170130204

The present invention relates to a composition for inducing direct transdifferentiation of a somatic cell into a vascular progenitor cell and a use thereof and, more specifically, to a composition for inducing direct transdifferentiation of a somatic cell into a vascular progenitor cell, a pharmaceutical composition for the prevention or treatment of ischemic vascular diseases, a cell therapeutic agent for ...
Heterocyclic compounds as pi3k-y inhibitors
Unist(ulsan National Institute Of Science And Techology)
May 11, 2017 - N°20170129899

Or pharmaceutically acceptable salts or stereoisomers thereof, which are inhibitors of pi3k-γ which are useful for the treatment of disorders such as autoimmune diseases, cancer, cardiovascular diseases, and neurodegenerative diseases.
Pharmaceutical composition for treating cardio-cerebrovascular diseases and method for preparing the same
Unist(ulsan National Institute Of Science And Techology)
May 11, 2017 - N°20170128514

A pharmaceutical composition, including, parts by weight of: 100-170 of a ginkgo flavone, 40-100 of a jujube extract, 100-200 of an extract of a peel of trichosanthes kirilowii, 30-60 of a saponin of codonopsis, 50-100 of a saponin of american ginseng, 40-70 of a saponin of radix astragalu, 20-50 of hirudin, 3-10 of a coenzyme q10, 40-100 of a longan ...
Compositions and methods for treating and/or preventing cardiovascular disease
Amarin Pharmaceuticals Ireland Limited
May 11, 2017 - N°20170128406

In various embodiments, the present invention provides pharmaceutical compositions comprising fatty acids and methods for treating subjects using same.
Methods of treating cardiovascular diseases and predicting the efficacy of exercise therapy
Critical Care Diagnostics, Inc.
May 04, 2017 - N°20170122942

Methods of treating a subject having a cardiovascular disease, selecting a therapy for a subject having a cardiovascular disease, identifying a subject having a cardiovascular disease that will benefit or not benefit from exercise therapy, determining whether a subject having a cardiovascular disease should begin, continue, not begin, discontinue, or avoid exercise therapy, determining whether a subject having a cardiovascular ...
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