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Vascular Disease

Vascular Disease-related patent applications - as published by the U.S. Patent and Trademark Office (USPTO).


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Hgh determination for use to guide prevention of a major adverse cardiac event or a ...
Sphingotec Gmbh
August 17, 2017 - N°20170234889

A method of determining whether a subject has a vascular risk that can be reduced by blood pressure lowering therapy with antihypertensive drugs (e. G. Angiotensin converting enzyme inhibitor (ace inhibitor), angiotensin receptor blocker (arb), beta-adrenoreceptor blocker (beta-blocker) and/or statins) by determining the level of hgh, and/or its isoforms in a blood sample of said subject and comparing ...
Genetic markers for predicting responsiveness to therapy with hdl-raising or hdl mimicking agent
Hoffmann-la Roche Inc.
August 17, 2017 - N°20170233812

Genotyping methods and compositions for selecting patients with cardiovascular disease who will benefit from treatment with hdl-raising or hdl mimicking agent, in particular with a cetp inhibitor/modulator
Modulation of apolipoprotein c-iii (apociii) expression in lipoprotein lipase deficient (lpld) populations
Ionis Pharmaceuticals, Inc.
August 17, 2017 - N°20170233732

Provided herein are methods, compounds, and compositions for reducing expression of apociii mrna and protein in a patient with fredrickson type i dyslipidemia, fcs, lpld. Also provided herein are methods, compounds, and compositions for treating, preventing, delaying, or ameliorating fredrickson type i dyslipidemia, fcs, lpld, in a patient. Further provided herein are methods, compounds, and compositions for increasing hdl levels ...
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Vascular Disease Patent Applications
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19-nor neuroactive steroids and methods of use thereof
Ionis Pharmaceuticals, Inc.
August 17, 2017 - N°20170233432

And pharmaceutical compositions thereof. Such compounds are contemplated useful for the prevention and treatment of a variety of cns-related conditions, for example, treatment of sleep disorders, mood disorders, schizophrenia spectrum disorders, disorders of memory and/or cognition, movement disorders, personality disorders, autism spectrum disorders, pain, traumatic brain injury, vascular diseases, substance abuse disorders and/or withdrawal syndromes, tinnitus, status epilepticus.
Organic compounds
Intra-cellular Therapies, Inc.
August 17, 2017 - N°20170233399

The invention relates to novel inhibitors of phosphodiesterase 1 (pde1), useful for the treatment of diseases or disorders characterized by disruption of or damage to certain cgmp/pkg mediated pathways (e. G., in cardiac tissue). The invention further relates to pharmaceutical composition comprising the same and methods of treatment of cardiovascular disease and related disorders, e. G., congestive heart disease, atherosclerosis, ...
Aza-heteroaryl compounds as pi3k-gamma inhibitors
Intra-cellular Therapies, Inc.
August 17, 2017 - N°20170232016

And pharmaceutically acceptable salts thereof, wherein x, y, z, a, w, r4, r5, and r6 are defined herein, that inhibit the activity of phosphoinositide 3-kinases-gamma (pi3kγ) and are useful in the treatment of diseases related to the activity of pi3kγ including, for example, autoimmune diseases, cancer, cardiovascular diseases, and neurodegenerative diseases.
Vascular Disease Patent Pack
Download 215+ patent application PDFs
Vascular Disease Patent Applications
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For professional research & prior art discovery
inventor
  • 215+ full patent PDF documents of Vascular Disease-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
Preparation and uses of obeticholic acid
The Salk Institute For Biological Studies
August 10, 2017 - N°20170226149

Or a pharmaceutically acceptable salt, solvate or amino acid conjugate thereof. Obeticholic acid is useful for the treatment or prevention of a fxr mediated disease or condition, cardiovascular disease or cholestatic liver disease, and for reducing hdl cholesterol, for lowering triglycerides in a mammal, or for inhibition of fibrosis. The present invention also relates to processes for the synthesis of ...
Organic compounds
Intra-cellular Therapies, Inc.
August 10, 2017 - N°20170226117

The invention relates to novel inhibitors of phosphodiesterase 1 (pde1), useful for the treatment of diseases or disorders characterized by disruption of or damage to certain cgmp/pkg mediated pathways (e. G., in cardiac tissue). The invention further relates to pharmaceutical composition comprising the same and methods of treatment of cardiovascular disease and related disorders, e. G., congestive heart disease, atherosclerosis, ...
Fluorinated benzofuranyl-pyrimidine derivatives containing a suflone group
Bayer Pharma Aktiengesellschaft
August 10, 2017 - N°20170226092

The present invention relates to fluorinated benzofuranyl-pyrimidine derivatives containing a sulfone group of general formula (i) as described and defined herein, and methods for their preparation, their use for the treatment and/or prophylaxis of disorders, in particular of hyperproliferative disorders and/or virally induced infectious diseases and/or of cardiovascular diseases. The invention further relates to intermediate compounds useful ...
Piperazine derivatives as liver x receptor modulators
Vitae Pharmaceuticals, Inc.
August 10, 2017 - N°20170226067

Provided are novel compounds of formula (i): pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof, which are liver x receptor modulators, and which are useful in the treatment of diseases and disorders associated with the liver x receptor. Also provided are the compounds of formula (i) and pharmaceutical compositions thereof for treating atherosclerosis, cardiovascular disease, alzheimer's disease, dermatitis, dyslipidemia, cancer ...
Methods for reducing ldl-cholesterol
Rinat Neuroscience Corp.
August 10, 2017 - N°20170224816

The present invention relates to methods for the treatment of reducing ldl-cholesterol levels in a subject infected with hepatitis c virus (hcv) or at high risk of contracting hcv comprising administration to the subject in need thereof a therapeutically effective amount of an antagonist antibody which specifically binds to a human pcsk9 protein. The subject treatment can be used in ...
Nutritional support method for health issues
Cortcontrol
August 10, 2017 - N°20170224746

A method of improving the outcome or recovery for depression, diabetes, cardiovascular disease, alzheimers progression, or breast cancer. This method consists of administering a food which includes transfer factor, lactic acid generating bacteria, and/or glucans in appropriate combinations and dosage levels. The food reduces cortisol levels, enhances the immune system, and balances hormones and cytokines. Dosage amounts are dependent ...
Phospholipid-containing marine extracts for treatment of cardiovascular diseases
Neptune Technologies & Bioressources, Inc.
August 10, 2017 - N°20170224742

The present invention relates to a method of treatment and/or prevention of cardiovascular disease, rheumatoid arthritis, skin cancer, premenstrual syndrome, diabetes and transdermal transport enhancement. The method comprises the administration of a therapeutically effective amount of krill and/or marine oil to a patient. The present invention also relates to a composition for the treatment and/or prevention of ...
Vascular Disease Patent Pack
Download 215+ patent application PDFs
Vascular Disease Patent Applications
Download 215+ Vascular Disease-related PDFs
For professional research & prior art discovery
inventor
  • 215+ full patent PDF documents of Vascular Disease-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
Novel 3-amino-pyrrolo[3,4-c]pyrazole-5(1h, 4h,6h) carbaldehyde derivatives
Immunomedics, Inc.
August 03, 2017 - N°20170217991

Wherein a, b, r1, r2, r3, r4, r5, r6, r7, r8, r9 and r10 are as defined above. The invention further relates to pharmaceutical compositions comprising the compounds and pharmaceutically acceptable salts and to methods of treating diabetes mellitus and its complications, cancer, ischemia, inflammation, central nervous system disorders, cardiovascular disease, alzheimer's disease and dermatological disase pression, virus diseases, inflammatory ...
Organic compounds
Intra-cellular Therapies, Inc.
August 03, 2017 - N°20170217975

The invention relates to novel inhibitors of phosphodiesterase 1 (pde1), useful for the treatment of diseases or disorders characterized by disruption of or damage to certain cgmp/pkg mediated pathways (e. G., in cardiac tissue). The invention further relates to pharmaceutical composition comprising the same and methods of treatment of cardiovascular disease and related disorders, e. G., congestive heart disease, atherosclerosis, ...
4-aryl-n-phenyl-1,3,5-triazin-2-amines containing a sulfoximine group
Bayer Intellectual Property Gmbh
August 03, 2017 - N°20170217949

The present invention relates to 4-aryl-n-phenyl-1,3,5-triazin-2-amines containing a sulfoximine group of general formula (i) or (ia) as described and defined herein, and methods for their preparation, their use for the treatment and/or prophylaxis of disorders, in particular of hyper-proliferative disorders and/or virally induced infectious diseases and/or of cardiovascular diseases. The invention further relates to intermediate ...
Fluorinated benzofuranyl-pyrimidine derivatives containing a sulfoximine group
Bayer Pharma Aktiengesellschaft
August 03, 2017 - N°20170217938

The present invention relates to fluorinated benzofuranyl-pyrimidine derivatives containing a sulfoximine group of general formula (i) as described and defined herein, and methods for their preparation, their use for the treatment and/or prophylaxis of disorders, in particular of hyper-proliferative disorders and/or virally induced infectious diseases and/or of cardiovascular diseases. The invention further relates to intermediate compounds useful ...
Dry powder inhaler
Mannkind Corporation
August 03, 2017 - N°20170216538

A dry powder inhaler including replaceable cartridges containing a dry powder for local or systemic delivery through the pulmonary tract and lungs is disclosed. The inhalers are used with inhalable dry powders, including medicament formulations comprising active agents for local or systemic delivery and for the treatment of diseases such as, pulmonary hypertension, cardiovascular disease, anaphylaxis, diabetes, obesity, cancer, and ...
Aspirin formulation for increased efficacy
Vitalis Llc
August 03, 2017 - N°20170216320

Provided are methods for enhancing the efficacy of aspirin. Also provided are methods for reducing pain or preventing or treating heart attack, stroke or blood clot in a subject in need thereof. The methods entail orally administering to the subject a first composition comprising a first amount of aspirin, and a second composition comprising a second amount of aspirin, wherein ...
Aldose reductase inhibitors and uses thereof
The Trustees Of Columbia University In The City Of New York
August 03, 2017 - N°20170216292

The present invention relates to novel compounds and pharmaceutical compositions thereof, and methods for promoting healthy aging of skin, the treatment of skin disorders, the treatment of cardiovascular disorders, the treatment of renal disorders, the treatment of angiogenesis disorders, such as cancer, treatment of tissue damage, such as non-cardiac tissue damage, the treatment of evolving myocardial infarction, and the treatment ...
Aldose reductase inhibitors and uses thereof
The Trustees Of Columbia University In The City Of New York
August 03, 2017 - N°20170216291

The present invention relates to novel compounds and pharmaceutical compositions thereof, and methods for promoting healthy aging of skin, the treatment of skin disorders, the treatment of cardiovascular disorders, the treatment of renal disorders, the treatment of angiogenesis disorders, such as cancer, treatment of tissue damage, such as non-cardiac tissue damage, the treatment of evolving myocardial infarction, and the treatment ...
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