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Vaccine

Vaccine-related patent applications - as published by the U.S. Patent and Trademark Office (USPTO).


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Non-nucleoside reverse transcriptase inhibitors
December 07, 2017 - N°20170349585

Are hiv reverse transcriptase inhibitors, wherein r1, r2, re, l, m and z are defined herein. The compounds of formula i and their pharmaceutically acceptable salts are useful in the inhibition of hiv reverse transcriptase, the prophylaxis and treatment of infection by hiv and in the prophylaxis, delay in the onset or progression, and treatment of aids. The compounds and ...
Novel synthetic anticancer, antifungal, and antibacterial vaccines
Wayne State University
December 07, 2017 - N°20170348414

Described herein are compounds for use in vaccine compositions which contain natural or synthetic carbohydrate antigens. Such vaccines may be highly immunologically active due to the conjugation with an immune-stimulating protein or with a monophosphorylated lipid a derivative, and may be self-adjuvanting due to the presence of a monophosphorylated lipid a derivative. Treatments for cancer and fungal and bacterial infections ...
Influenza h5 vaccines
Wayne State University
December 07, 2017 - N°20170348413

In one aspect, the invention is thus directed to h5 protein of clade 1 h5n1 virus for use in a method of treating or preventing infections with h5n1 virus of a different clade, namely of a clade different from clade 1 or from any clade with the exception of clade 1, respectively.
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Compositions and methods related to viral vaccines
Ohio State Innovation Foundation
December 07, 2017 - N°20170348409

Provided herein are methods and compositions relating to infectious bursal disease virus (ibdv), and vaccines for treatment and prevention thereof.
Staphylococcus aureus proteins and nucleic acids
Glaxosmithkline Biologicals, Sa
December 07, 2017 - N°20170348407

The invention provides proteins from staphylococcus aureus including amino acid sequences and the corresponding nucleotide sequences. The proteins are useful for vaccines, immunogenic compositions, diagnostics, enzymatic studies and also as targets for antibiotics.
Subunit immersion vaccines for fish
Fvg Limited
December 07, 2017 - N°20170348406

The present disclosure provides an immersion vaccine for fish comprising at least one isolated antigen, specifically a recombinant antigen, such as is f. Psychrophilum and/or infectious pancreatic necrosis virus (ipnv).
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Use of microrna precursors as drugs for inducing cd34-positive adult stem cell expansion
The Regents Of The University Of California
November 30, 2017 - N°20170342418

This invention generally relates to a composition and its production method useful for developing drugs/vaccines and/or therapies against a variety of degenerative diseases in humans. Particularly, the present invention teaches the essential steps of production and purification processes necessary for producing small hairpin-like rna (shrna) compositions, such as microrna precursors (pre-mirna) and short interfering rnas (sirna), which are ...
Pestivirus
Intervet Inc.
November 30, 2017 - N°20170342387

The present invention relates to a novel porcine pestivirus, to proteins of the virus and to vaccines based upon the virus and proteins thereof. The invention also relates to dna fragments comprising a gene of the virus and to dna vaccines based upon genes of the virus. Furthermore the invention relates to antibodies that are reactive with the novel virus ...
Hla-dr binding peptides and their uses
University Of Washington
November 30, 2017 - N°20170342126

The present invention provides hla-dr (mhc class ii) binding peptides derived from the ovarian/breast cancer associated antigens, human epidermal growth factor receptor 2 (her-2/neu), carcinoembryonic antigen (cea), insulin growth factor binding protein 2 (igfbp-2), and cyclin d1. The immunogenic peptides can be used in cancer vaccines.
Immunotherapy against erbb-3 receptor
Takis S.r.l.
November 30, 2017 - N°20170342123

The present invention describes methods and pharmaceutical compositions for the treatment of cancer in mammals, more particularly in human subjects. More specifically, the invention concerns anti-tumor vaccines based upon plasmid dna and/or genetic vectors carrying a codon-usage optimized sequence and coding for a mutant form of the erbb-3 receptor. Furthermore, the invention refers to monoclonal antibodies directed against the ...
Vaccines and vaccine components for inhibition of microbial cells
Pastoral Greenhouse Gas Research Limited
November 30, 2017 - N°20170342112

The invention encompasses components from microbial cells which are useful for antibody production, including peptides, polypeptides comprising these peptides, polynucleotides which encode these peptides or polypeptides, and antibodies directed to these peptides, polypeptides, or polynucleotides. The invention also encompasses to expression vectors and host cells for producing these peptides, polypeptides, polynucleotides, and antibodies. The invention further encompasses methods and compositions, ...
A rabies composition comprising pika adjuvant
Yisheng Biopharma (singapore) Pte Ltd
November 30, 2017 - N°20170340727

The present disclosure provides a rabies composition comprising iprv and pika adjuvant, and the pharmaceutical use thereof. The present disclosure also discloses a method for prophylaxis or therapeutic treatment of rabies virus infection, the method comprises a step of administering the rabies vaccine composition to a host. The rabies composition is more stable and safe, and is able to induce ...
Combination piv3/hmpv rna vaccines
Modernatx, Inc.
November 30, 2017 - N°20170340725

The disclosure relates to respiratory virus ribonucleic acid (rna) vaccines and combination vaccines, as well as methods of using the vaccines and compositions comprising the vaccines.
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Novel polysaccharide and uses thereof
Glycovaxyn Ag
November 30, 2017 - N°20170340718

Provided herein is a novel e. Coli o polysaccharide, o25b. Also provided herein are prokaryotic host cells containing enzymes (e. G., glycosyltransferases) used in o25b production. The host cells provided herein produce o25b bioconjugates, wherein said bioconjugates contain o25b linked to a carrier protein. Further provided herein are compositions, e. G., pharmaceutical compositions, including o25b ...
Recombinant swinepox virus and vaccines
Ceva Sante Animale
November 23, 2017 - N°20170335343

The present invention relates to novel recombinant swinepox viruses and their use in vaccine compositions. The re-combinant swinepox viruses of the invention are produced 5 by inserting one or more foreign genes into il-18 binding protein (il18bp) gene of swinepox virus. The invention is particularly suited to produce swine vaccines, particularly for vaccinating swine against pcv2 infection.
Identification and use of novopeptides for the treatment of cancer
Calviri, Inc.
November 23, 2017 - N°20170334963

Compositions, methods, systems, apparatus and/or articles of manufacture are disclosed for reducing the susceptibility of a population and/or members thereof to cancer, which may include anti-cancer vaccines, components thereof which may include novopeptides, and methods relating thereto.
Fcrn-targeted antigen fusion proteins
Texas A&m University System
November 23, 2017 - N°20170334962

The invention disclosed herein generally relates to fusion proteins for use alone or as adjuvants or antigen delivery vehicles for vaccines.
Immunogenic wt-1 peptides and methods of use thereof
Memorial Sloan Kettering Cancer Center
November 23, 2017 - N°20170334951

This invention provides peptides, immunogenic compositions and vaccines, and methods of treating, reducing the incidence of, and inducing immune responses to a wt-1-expressing cancer, comprising peptides derived from the wt-1 protein.
Lipidated immune response modifier compound compositions, formulations, and methods
3m Innovative Properties Company
November 23, 2017 - N°20170333553

The compound n-(4-{[4-amino-2-butyl-1h-imidazo[4,5-c]quinolin-1-yl]oxy}butyl)octadecanamide is a useful drug compound for enhancing immune response and can be used, for example, as a vaccine adjuvant and a cancer treatment.
Poxviral vaccines
Glaxosmithkline Biologicals, Sa
November 23, 2017 - N°20170333550

The present application relates to novel administration regimens for poxviral vectors comprising nucleic acid constructs encoding antigenic proteins and invariant chains. In particular the use of said poxviral vectors for priming or for boosting an immune response is disclosed.
Pertussis vaccines and methods of making and using
Regents Of The University Of Minnesota
November 23, 2017 - N°20170333547

Bordetella pertussis iron receptor proteins or portions thereof (e. G., one or more extracellular domains), alone or spliced into b. Pertussis scaffold proteins (e. G., fimbrial or flagellin), are provided and can be used in acellular vaccines to protect against pertussis or other bordetella diseases in humans and non-human mammals. In addition, bordetella species grown under iron-starved conditions are provided ...
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