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Vaccine patents



      
           
This page is updated frequently with new Vaccine-related patent applications. Subscribe to the Vaccine RSS feed to automatically get the update: related Vaccine RSS feeds. RSS updates for this page: Vaccine RSS RSS


Anti-idiotype antibody against anti-c-met antibody

Anti-idiotype antibody against anti-c-met antibody

Date/App# patent app List of recent Vaccine-related patents
10/09/14
20140303171
 Hiv protease inhibitors patent thumbnailHiv protease inhibitors
Compounds of formula i are disclosed: wherein a, r1, r2, r3, r4a, r4b, r5, r6 and r7 are defined herein. The compounds encompassed by formula i include compounds which are hiv protease inhibitors.
10/09/14
20140302517
 Anti-idiotype antibody against anti-c-met antibody patent thumbnailAnti-idiotype antibody against anti-c-met antibody
Disclosed are an anti-idiotype antibody that specifically binds to an idiotope site of an anti-c-met antibody, the use of the anti-idiotype antibody for detecting the anti-c-met antibody, and methods, polypeptides, polynucleotides, compositions, and vaccines related thereto.. .
10/09/14
20140302489
 Identification of protective antigenic determinants of porcine reproductive and respiratory syndrome virus and uses thereof patent thumbnailIdentification of protective antigenic determinants of porcine reproductive and respiratory syndrome virus and uses thereof
The invention relates to a polypeptide of a protective antigenic determinant (pad polypeptide) of porcine reproductive and respiratory syndrome virus (prrsv) and nucleic acids encoding a pad polypeptide. The pad polypeptide and nucleic acids encoding a pad polypeptide are useful in the development of antibodies directed to pad, vaccines effective in providing protection against prrsv infection, and diagnostic assays detecting the presence of pad antibodies generated by a pad-specific vaccine.
10/09/14
20140302124
 Cytotoxic t lymphocyte inducing immunogens for prevention treatment and diagnosis of influenza virus infection patent thumbnailCytotoxic t lymphocyte inducing immunogens for prevention treatment and diagnosis of influenza virus infection
Influenza virus infection and the resulting complications are a significant global public health problem and understanding the overall immune response to infection will contribute to appropriate management of the disease and its potentially severe complications. Improving humoral immunity to influenza is the target of current conventional influenza vaccines, however, these are generally not cross-protective.
10/09/14
20140302120
 Conjugates of synthetic tlr agonists and uses therefor patent thumbnailConjugates of synthetic tlr agonists and uses therefor
The invention provides tlr agonists and conjugates thereof useful in vaccines and to prevent, inhibit or treat a variety of disorders including pathogen infection and asthma.. .
10/09/14
20140302098
 Yeast-based vaccines as immunotherapy patent thumbnailYeast-based vaccines as immunotherapy
Compositions and methods for treating and/or preventing a variety of diseases and conditions that are amenable to immunotherapy and, in one particular embodiment, compositions and methods for treating and/or preventing cancer in an animal are described. Specifically improvements related to the use of a yeast-based vaccine comprising a yeast vehicle and an antigen that is selected to elicit an antigen-specific cellular and humoral immune response in an animal, for use in prophylactic and/or therapeutic vaccination and the prevention and/or treatment of a variety of diseases and conditions are disclosed..
10/09/14
20140302088
 Compositions and methods for dengue virus chimeric constructs in vaccines patent thumbnailCompositions and methods for dengue virus chimeric constructs in vaccines
Embodiments herein report compositions, uses and manufacturing of dengue virus constructs and live attenuated dengue viruses. Some embodiments concern a composition that includes, but is not limited to, a tetravalent dengue virus composition.
10/09/14
20140302087
 Manufacture of vaccines that contain both hepatitis b virus surface antigen and surfactant patent thumbnailManufacture of vaccines that contain both hepatitis b virus surface antigen and surfactant
When preparing hbsag for use in a combination vaccine, it is known to add a non-ionic detergent after the hbsag has been purified. Adding detergents after purification of hbsag is not optimal, however, as it requires a separate processing step during manufacture.
10/09/14
20140302084
 Immunogenic protein conjugates and method for making and using the same patent thumbnailImmunogenic protein conjugates and method for making and using the same
Production of protein conjugate vaccines by use of transpeptidase enzymes, such as sortase enzymes. For example, homogenous immunoconjugates (e.g., a population of molecules having the same structure) formed by conjugating an antigenic polypeptide and a bacterial capsule component are provided.
10/09/14
20140302080
 Stabilized human immunodeficiency virus (hiv) envelope (env) trimer vaccines and methods of using same patent thumbnailStabilized human immunodeficiency virus (hiv) envelope (env) trimer vaccines and methods of using same
The invention features stabilized human immunodeficiency virus (hiv) envelope (env) trimers. The invention also features vaccines, nucleic acids, and vectors to deliver and/or facilitate production of the stabilized hiv env trimers.
10/09/14
20140302079
Novel influenza hemagglutinin protein-based vaccines
Novel vaccines are provided that elicit broadly neutralizing anti-influenza antibodies. Some vaccines comprise nanoparticles that display hemagglutinin trimers from influenza virus on their surface.
10/09/14
20140302078
Haemophilus influenzae type b
Polypeptides comprising various amino acid sequences derived from haemophilus influenzae type b, including a number of lipoproteins. These can be used in the development of vaccines for preventing and/or treating bacterial meningitis.
10/09/14
20140302063
Influenza virus antibody compositions
The present invention relates to unique cdr3 amino acid sequences, and to antibodies comprising said sequences. Also provided are therapeutic applications of said antibodies for use in treating or preventing influenza infection, diagnostic applications of said antibodies for use in detecting influenza virus, potency testing of influenza virus vaccines, and screening applications of said antibodies for use in designing a universal influenza vaccine..
10/02/14
20140296824
Apparatus and methods for self-administration of vaccines and other medicaments
A medicament delivery device includes a housing, a medicament container disposed within the housing, an activation mechanism, a cover and an electronic circuit system. The activation mechanism includes an energy storage member configured to produce a force to deliver the dose of a medicament and/or vaccine.
10/02/14
20140296504
Hepatitis b viral variants with reduced susceptibility to nucleoside analogs and uses thereof
The present invention relates generally to viral variants exhibiting reduced sensitivity to particular agents and/or reduced interactivity with immunological reagents. More particularly, the present invention is directed to hepatitis b virus (hbv) variants exhibiting complete or partial resistance to nucleoside or nucleotide analogs and/or reduced interactivity with antibodies to viral surface components including reduced sensitivity to these antibodies.
10/02/14
20140296464
Chromatography medium
The present invention provides a chromatography medium comprising one or more electrospun polymer nanofibres which form a stationary phase comprising a plurality of pores through which a mobile phase can permeate and use of the same in chromatography, such as the isolation of recombinant proteins, monoclonal antibodies, viral vaccines and plasmid dna. The invention further provides for the use of the chromatographic medium in a simulated moving bed system..
10/02/14
20140295409
Metapneumovirus strains and their use in vaccine formulations and as vectors for expression of antigenic sequences
The present invention provides an isolated mammalian negative strand rna virus, metapneumovirus (mpv), within the sub-family pneumoviridae, of the family paramyxoviridae. The invention also provides isolated mammalian negative strand rna viruses identifiable as phylogenetically corresponding or relating to the genus metapneumovirus and components thereof.
10/02/14
20140294930
Streptococcal glcnac-lacking glycopolypeptides, cell wall carbohydrates, streptococcus vaccines, and methods for making and using them
In alternative embodiments, the invention provides vaccines, pharmaceutical compounds and formulations for diagnosing, preventing, treating or ameliorating group a streptococcus (gas), group c streptococcus (gcs), or group a streptococcus (ggs), infections, or other pathogenic streptococcus infections. In alternative embodiments, the invention provides compositions such as diagnostic tests, assays, immunoassays and test strips, and methods, for detecting or diagnosing the presence of a streptococcal infection, e.g., group a streptococcus (gas), group c streptococcus (gcs), or group a streptococcus (ggs), infections, or other pathogenic streptococcus infections..
10/02/14
20140294919
Vaccines
The present invention relates to efficient devices for administration of pharmaceutical agents into the skin of the human body. In particular the present invention provides devices for vaccination into the skin.
10/02/14
20140294895
Expression of protective antigens in transgenic chloroplasts and the production of improved vaccines
Vaccines for conferring immunity in mammals to infective pathogens are provided, as well as vectors and methods for plastid transformation of plants to produce protective antigens and vaccines for oral delivery. The invention further provides transformed plastids having the ability to survive selection in both the light and the dark, at different developmental stages by using genes coding for two different enzymes capable of detoxifying the same selectable marker, driven by regulatory signals that are functional in proplastids as well as in mature chloroplasts.
10/02/14
20140294893
Recombinant nonpathogenic mdv vector providing multivalent immunity
The present invention relates to the field of veterinary vaccines, in particular to that of vector vaccines for poultry based on recombinant nonpathogenic marek's disease virus (npmdv). The recombinant npmdv of the invention expresses stably and effectively two heterologous genes each originating from a different micro-organism: the fusion protein gene from newcastle disease virus, and the viral protein 2 gene from infectious bursal disease virus.
10/02/14
20140294892
Construction of west nile virus and dengue virus chimeras for use in a live virus vaccine to prevent disease caused by west nile virus
The present invention relates to attenuated, immunogenic west nile virus chimeras built on a dengue virus backbone for the production of immunogenic, live, attenuated west nile virus vaccines.. .
10/02/14
20140294890
Recombinant adenovirus vaccines
Recombinant adenovirus vaccines comprising recombinant adenoviruses whose hexon, fiber or protein ix capsid proteins are engineered to include exogenous peptide segments, e.g. Vaccines for human papillomavirus (hpv) and malaria..
10/02/14
20140294889
Use of the pacap as a molecular adjuvant for vaccines
The present invention relates to the use of the pituitary adenylate cyclase activating peptide (pacap) as a molecular adjuvant for vaccines. Among other applications, these vaccines may be used in the protection against infectious agents such as viruses, bacteria and ectoparasites affecting mammals, birds and aquatic organisms.
10/02/14
20140294883
Vaccine
The present invention is concerned with the development of a vaccine against aeromonas hydrophila for use especially in fish. The invention provides an immunogenic s-layer protein of approximately 50 kda of a.
10/02/14
20140294882
Compositions and methods for detecting, treating, and protecting against fusobacterium infection
The present invention relates to protecting against, treating, and detecting fusobacteria infections. Compositions and methods derived from nucleic acid and protein sequences of a 40 kda adhesin protein are provided to protect against, treat, and detect fusobacteria infections in a subject.
10/02/14
20140294879
Modified rsv f proteins and methods of their use
The present invention is generally related to modified or mutated respiratory syncytial virus fusion (f) proteins and methods for making and using them, including immunogenic compositions such as vaccines for the treatment and/or prevention of rsv infection.. .
10/02/14
20140294876
Amyloid beta 1-6 antigen arrays
The present invention is related to the fields of molecular biology, virology, immunology and medicine. The invention provides a composition comprising an ordered and repetitive antigen or antigenic determinant array, and in particular an aβ1-6 peptide-vlp-composition.
10/02/14
20140294871
Amino acid sequences for controlling pathogens
The present invention relates to antimicrobial peptides, isolated and purified from extracts of tilapia (oreochromis niloticus) gills. Such peptides may be produced by chemical synthesis or by expression in heterologous systems, such as bacteria and yeasts, by conventional molecular biology techniques.
09/25/14
20140287476
Vibrio cholerae 0139 conjugate vaccines
The disclosure pertains to conjugates of the capsular polysaccharide of vibrio cholerae o139, or a structurally and/or immunologically related oligo- or poly-saccharide, and a carrier. These conjugates are useful as pharmaceutical compositions and/or vaccines to induce serum antibodies which have bactericidal (vibriocidal) activity against v.
09/25/14
20140286999
Vaccine preparation containing trifunctional antibodies with antigen immunogenicity enhancer properties
The present invention refers to a pharmaceutical composition containing trifunctional bispecific and/or trispecific antibodies being capable of binding to a specific target antigen(s) for use in a method of immunizing mammals against diseases in which said target antigen(s) is (are) involved, and further to a pharmaceutical composition containing trifunctional bispecific and/or trispecific antibodies being capable of binding to (a) specific target antigen (s) which is (are) involved in a disease of a mammal, specifically a human.. .
09/25/14
20140286996
Modified gram-negative bacteria for use as vaccines
The invention relates to gram-negative bacteria carrying an inactivated gene encoding a glycosyltransferase involved in the synthesis of the core of the lps of said gram-negative bacteria, wherein said inactivated gene results in the synthesis of a lps having a modified core. These strains have an attenuated virulence but induce a humoral immunity sufficient for ensuring vaccination of the host..
09/25/14
20140286994
Norovirus vaccine formulations
The present invention relates to antigenic and vaccine compositions comprising norovirus antigens and adjuvants, in particular, mixtures of monovalent vlps and mixtures of multivalent vlps, and to a process for the production of both monovalent and multivalent vlps, the vlps comprising capsid proteins from one or more norovirus genogroups.. .
09/25/14
20140286993
Immune methods against influenza viruses and combinatorial vaccines thereof
The invention provides a method of preventing the spreading of influenza viruses, and the factors making up the said method, and especially provides one type of combinatorial vaccine and the immunization method thereof. Two of more influenza vaccines are inoculated by a certain sequence, and each influenza vaccine vaccines is inoculated at least once, and the inoculation take place two or more times; wherein each influenza vaccine includes one or more antigens, the immunogenic fragments thereof, or the coding genes thereof, and further includes a different antigen, the immunogenic fragments or the coding gene of the different antigen..
09/25/14
20140286985
Simple vaccines from dna launched suicidal flaviviruses
Immunogenic compositions relating to dna launched suicidal flaviviruses and methods of administering the same are described herein.. .
09/25/14
20140286983
Dengue virus e-glycoprotein polypeptides containing mutations that eliminate immunodominant cross-reactive epitopes
Described herein are dengue virus e-glycoprotein polypeptides containing mutations that eliminate immunodominant cross-reactive epitopes associated with immune enhancement. The disclosed dengue virus e-glycoproteins optionally further include mutations that introduce a strong cd4 t cell epitope.
09/25/14
20140286982
Multimeric multiepitope influenza vaccines
An isolated polynucleotide encoding an influenza multi-epitope polypeptide, wherein the multi-epitope polypeptide comprises multiple copies of a plurality of influenza virus peptide epitopes wherein the polypeptide is b(x1zx2z . .
09/25/14
20140286981
Broadly reactive mosaic peptide for influenza vaccine
The invention provides for mosaic influenza virus ha and na sequences and uses thereof.. .
09/25/14
20140286980
Infectious clones of torque teno virus
The present invention is directed to novel nucleotide and amino acid sequences of torque teno virus (“ttv”), including novel genotypes thereof, all of which are useful in the preparation of vaccines for treating and preventing diseases in swine and other animals. Vaccines provided according to the practice of the invention are effective against multiple swine ttv genotypes and isolates.
09/18/14
20140275478
Vaccines against chlamydia sp.
The present invention describes an efficient vaccine against a chlamydia trachomatis (ct). The vaccine is based on recombinant fusion molecules that are capable of generating a high titered neutralizing antibody response that is protective against various ct serovars.
09/18/14
20140273209
Artificial immune system: methods of use
The present invention relates to methods of constructing an integrated artificial immune system that comprises appropriate in vitro cellular and tissue constructs or their equivalents to mimic the normal tissues that interact with vaccines in mammals. The artificial immune system can be used to test the efficacy of vaccine candidates in vitro and thus, is useful to accelerate vaccine development and testing drug and chemical interaction with the immune system..
09/18/14
20140271815
Heat-and freeze-stable vaccines and methods of making and using same
A vaccine adjuvant composition comprising: a lipid selected from the group consisting of: dipalmitoyl phosphatidlcholine (dppc), dipalmitoyl phosphatidylglycerol (dppg), dioleoyl phosphatidylcholine (dopc), and cholesterol and containing a positively or negatively charged lipid with associated/entrapped protein antigen.. .
09/18/14
20140271725
Small molecule enhancer for dendritic cell cancer vaccines
Disclosed is a method of treating cancer, comprising administering to a mammal in need thereof a therapeutically effective amount of a compound that inhibits a plurality of mammalian dipeptidyl peptidase (dpp) iv activity and/or structural homologues thereof (dash) serine proteases. Also disclosed is a method of (a) increasing antitumor immunity, (b) stimulating or enhancing an immune response, (c) treating a condition characterized by abnormal cell proliferation, (d) increasing cytokine and/or chemokine production, or (e) stimulating or enhancing production of t-cells, in a mammal, comprising administering to a mammal in need thereof an effective amount of a compound that inhibits a plurality of mammalian dash serine proteases.
09/18/14
20140271718
Novel type 1 diabetes vaccines, and methods of use
The subject invention provides compositions for alleviating type 1 diabetes (t1d). In preferred embodiments, the compositions comprise an effective amount of one or more antigen presenting cells (apcs) that have been pulsed with one or more bacterial isolates and/or compounds from the isolates.
09/18/14
20140271716
Intra-testicular injection of immunogens
A method for inducing an immune response by injecting an immunogen into a subject's testis. A composition for intra-testicular injection including an immunogen such as a rabies vaccine and a chemical sterilant formed of zinc gluconate and an amino acid capable of forming an aqueous solution neutralized to a ph from 6.0 to 7.5.
09/18/14
20140271710
Liquid stable bovine virus vaccines
The present invention discloses liquid stable bovine vaccines that comprise a live attenuated virus, in sucrose, arginine, and methionine. The present invention also discloses the manufacture of such vaccines and methods of protecting an animal by administration of such vaccines..
09/18/14
20140271709
Bovine virus vaccines that are liquid stable
The present invention discloses liquid stable bovine vaccines that comprise a live attenuated virus, and a sugar alcohol. The present invention also discloses the manufacture of such vaccines and methods of protecting an animal by administration of such vaccines..
09/18/14
20140271708
Novel methods for providing long-term protective immunity against rabies in animals, based upon administration of replication-deficient flavivirus expressing rabies g
The present invention relates to compositions comprising replication defective chimeric flavivirus anti-rabies vaccines, methods of producing the vaccines, and the administration of such vaccines to companion animals, including dogs. The invention further relates to methods for providing long-term protective immunity against rabies in companion animals, including dogs and cats..
09/18/14
20140271702
Vaccination of companion animals to elicit a protective immune response against tick infestations and tick-borne pathogen transmission
Compositions of either the aquaporin protein from the cattle tick, rhipicephalus microplus, or a nucleic acid construct incorporating a nucleic acid sequence encoding this aquaporin protein, are effective for eliciting a protective immune response against other tick species in non-bovine animals. The r.
09/18/14
20140271698
Porcine reproductive and respiratory syndrome virus, compositions, vaccine and methods of use
The present invention relates to porcine reproductive and respiratory syndrome virus (prrsv) mutant strains having increased stability; compositions containing the strains or antigens derived therefrom; vaccines containing the strains, including killed, attenuated or subunit vaccines; nucleic acids encoding prrsv polypeptides, polypeptides encoded by the nucleic acids, including antigenic fragments thereof; antibodies which specifically bind to said polypeptides, and methods making and using thereof.. .
09/18/14
20140271691
Therapeutic cancer vaccine targeted to haah (aspartyl-[asparaginyl]-beta-hydroxylase)
The present invention encompasses a cancer vaccine therapy targeting aspartyl-[asparaginyl]-β-hydroxylase (haah). The present invention contemplate bacteriophage expressing haah peptide fragments and methods for using said bacteriophage in methods of treating cancer..
09/18/14
20140271690
Peptide vaccine for prevention and immunotherapy of dementia of the alzheimer's type
The present disclosure is directed to individual aβ peptide immunogen constructs, peptide compositions comprising these aβ peptide immunogen constructs and mixtures thereof, pharmaceutical compositions including vaccine formulations comprising these aβ peptide immunogen constructs, with the individual aβ peptide immunogen constructs having the n-terminus of the aβ peptide as the b cell (b) epitopes linked through spacer residue(s) to heterologous t helper cell (th) epitopes derived from pathogen proteins that act together to stimulate the generation of highly specific antibodies directed against the n-terminus of the aβ peptide offering protective immune responses to patients at risk for, or with, alzheimer's disease.. .
09/18/14
20140271689
Therapeutic cancer vaccine targeted to haah (aspartyl-[asparaginyl]-beta-hydroxylase)
The present invention encompasses a cancer vaccine therapy targeting aspartyl-[asparaginyl]-β-hydroxylase (haah). The present invention contemplate bacteriophage expressing haah peptide fragments and methods for using said bacteriophage in methods of treating cancer..
09/18/14
20140271563
Effect of an attenuated bordetella strain against allergic disease
Described herein are compositions, vaccines, and methods that include use of a mutated bordetella strain against allergic diseases such as asthma and skin inflammation. Also described are kits.


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This listing is a sample listing of patent applications related to Vaccine for is only meant as a recent sample of applications filed, not a comprehensive history. There may be associated servicemarks and trademarks related to these patents. Please check with patent attorney if you need further assistance or plan to use for business purposes. This patent data is also published to the public by the USPTO and available for free on their website. Note that there may be alternative spellings for Vaccine with additional patents listed. Browse our RSS directory or Search for other possible listings.
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