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Vaccine patents



      
           
This page is updated frequently with new Vaccine-related patent applications. Subscribe to the Vaccine RSS feed to automatically get the update: related Vaccine RSS feeds. RSS updates for this page: Vaccine RSS RSS


Date/App# patent app List of recent Vaccine-related patents
09/25/14
20140287476
 Vibrio cholerae 0139 conjugate vaccines patent thumbnailVibrio cholerae 0139 conjugate vaccines
The disclosure pertains to conjugates of the capsular polysaccharide of vibrio cholerae o139, or a structurally and/or immunologically related oligo- or poly-saccharide, and a carrier. These conjugates are useful as pharmaceutical compositions and/or vaccines to induce serum antibodies which have bactericidal (vibriocidal) activity against v.
09/25/14
20140286999
 Vaccine preparation containing trifunctional antibodies with antigen immunogenicity enhancer properties patent thumbnailVaccine preparation containing trifunctional antibodies with antigen immunogenicity enhancer properties
The present invention refers to a pharmaceutical composition containing trifunctional bispecific and/or trispecific antibodies being capable of binding to a specific target antigen(s) for use in a method of immunizing mammals against diseases in which said target antigen(s) is (are) involved, and further to a pharmaceutical composition containing trifunctional bispecific and/or trispecific antibodies being capable of binding to (a) specific target antigen (s) which is (are) involved in a disease of a mammal, specifically a human.. .
09/25/14
20140286996
 Modified gram-negative bacteria for use as vaccines patent thumbnailModified gram-negative bacteria for use as vaccines
The invention relates to gram-negative bacteria carrying an inactivated gene encoding a glycosyltransferase involved in the synthesis of the core of the lps of said gram-negative bacteria, wherein said inactivated gene results in the synthesis of a lps having a modified core. These strains have an attenuated virulence but induce a humoral immunity sufficient for ensuring vaccination of the host..
09/25/14
20140286994
 Norovirus vaccine formulations patent thumbnailNorovirus vaccine formulations
The present invention relates to antigenic and vaccine compositions comprising norovirus antigens and adjuvants, in particular, mixtures of monovalent vlps and mixtures of multivalent vlps, and to a process for the production of both monovalent and multivalent vlps, the vlps comprising capsid proteins from one or more norovirus genogroups.. .
09/25/14
20140286993
 Immune methods against influenza viruses and combinatorial vaccines thereof patent thumbnailImmune methods against influenza viruses and combinatorial vaccines thereof
The invention provides a method of preventing the spreading of influenza viruses, and the factors making up the said method, and especially provides one type of combinatorial vaccine and the immunization method thereof. Two of more influenza vaccines are inoculated by a certain sequence, and each influenza vaccine vaccines is inoculated at least once, and the inoculation take place two or more times; wherein each influenza vaccine includes one or more antigens, the immunogenic fragments thereof, or the coding genes thereof, and further includes a different antigen, the immunogenic fragments or the coding gene of the different antigen..
09/25/14
20140286985
 Simple vaccines from dna launched suicidal flaviviruses patent thumbnailSimple vaccines from dna launched suicidal flaviviruses
Immunogenic compositions relating to dna launched suicidal flaviviruses and methods of administering the same are described herein.. .
09/25/14
20140286983
 Dengue virus e-glycoprotein polypeptides containing mutations that eliminate immunodominant cross-reactive epitopes patent thumbnailDengue virus e-glycoprotein polypeptides containing mutations that eliminate immunodominant cross-reactive epitopes
Described herein are dengue virus e-glycoprotein polypeptides containing mutations that eliminate immunodominant cross-reactive epitopes associated with immune enhancement. The disclosed dengue virus e-glycoproteins optionally further include mutations that introduce a strong cd4 t cell epitope.
09/25/14
20140286982
 Multimeric multiepitope influenza vaccines patent thumbnailMultimeric multiepitope influenza vaccines
An isolated polynucleotide encoding an influenza multi-epitope polypeptide, wherein the multi-epitope polypeptide comprises multiple copies of a plurality of influenza virus peptide epitopes wherein the polypeptide is b(x1zx2z . .
09/25/14
20140286981
 Broadly reactive mosaic peptide for influenza vaccine patent thumbnailBroadly reactive mosaic peptide for influenza vaccine
The invention provides for mosaic influenza virus ha and na sequences and uses thereof.. .
09/25/14
20140286980
 Infectious clones of torque teno virus patent thumbnailInfectious clones of torque teno virus
The present invention is directed to novel nucleotide and amino acid sequences of torque teno virus (“ttv”), including novel genotypes thereof, all of which are useful in the preparation of vaccines for treating and preventing diseases in swine and other animals. Vaccines provided according to the practice of the invention are effective against multiple swine ttv genotypes and isolates.
09/18/14
20140275478
Vaccines against chlamydia sp.
The present invention describes an efficient vaccine against a chlamydia trachomatis (ct). The vaccine is based on recombinant fusion molecules that are capable of generating a high titered neutralizing antibody response that is protective against various ct serovars.
09/18/14
20140273209
Artificial immune system: methods of use
The present invention relates to methods of constructing an integrated artificial immune system that comprises appropriate in vitro cellular and tissue constructs or their equivalents to mimic the normal tissues that interact with vaccines in mammals. The artificial immune system can be used to test the efficacy of vaccine candidates in vitro and thus, is useful to accelerate vaccine development and testing drug and chemical interaction with the immune system..
09/18/14
20140271815
Heat-and freeze-stable vaccines and methods of making and using same
A vaccine adjuvant composition comprising: a lipid selected from the group consisting of: dipalmitoyl phosphatidlcholine (dppc), dipalmitoyl phosphatidylglycerol (dppg), dioleoyl phosphatidylcholine (dopc), and cholesterol and containing a positively or negatively charged lipid with associated/entrapped protein antigen.. .
09/18/14
20140271725
Small molecule enhancer for dendritic cell cancer vaccines
Disclosed is a method of treating cancer, comprising administering to a mammal in need thereof a therapeutically effective amount of a compound that inhibits a plurality of mammalian dipeptidyl peptidase (dpp) iv activity and/or structural homologues thereof (dash) serine proteases. Also disclosed is a method of (a) increasing antitumor immunity, (b) stimulating or enhancing an immune response, (c) treating a condition characterized by abnormal cell proliferation, (d) increasing cytokine and/or chemokine production, or (e) stimulating or enhancing production of t-cells, in a mammal, comprising administering to a mammal in need thereof an effective amount of a compound that inhibits a plurality of mammalian dash serine proteases.
09/18/14
20140271718
Novel type 1 diabetes vaccines, and methods of use
The subject invention provides compositions for alleviating type 1 diabetes (t1d). In preferred embodiments, the compositions comprise an effective amount of one or more antigen presenting cells (apcs) that have been pulsed with one or more bacterial isolates and/or compounds from the isolates.
09/18/14
20140271716
Intra-testicular injection of immunogens
A method for inducing an immune response by injecting an immunogen into a subject's testis. A composition for intra-testicular injection including an immunogen such as a rabies vaccine and a chemical sterilant formed of zinc gluconate and an amino acid capable of forming an aqueous solution neutralized to a ph from 6.0 to 7.5.
09/18/14
20140271710
Liquid stable bovine virus vaccines
The present invention discloses liquid stable bovine vaccines that comprise a live attenuated virus, in sucrose, arginine, and methionine. The present invention also discloses the manufacture of such vaccines and methods of protecting an animal by administration of such vaccines..
09/18/14
20140271709
Bovine virus vaccines that are liquid stable
The present invention discloses liquid stable bovine vaccines that comprise a live attenuated virus, and a sugar alcohol. The present invention also discloses the manufacture of such vaccines and methods of protecting an animal by administration of such vaccines..
09/18/14
20140271708
Novel methods for providing long-term protective immunity against rabies in animals, based upon administration of replication-deficient flavivirus expressing rabies g
The present invention relates to compositions comprising replication defective chimeric flavivirus anti-rabies vaccines, methods of producing the vaccines, and the administration of such vaccines to companion animals, including dogs. The invention further relates to methods for providing long-term protective immunity against rabies in companion animals, including dogs and cats..
09/18/14
20140271702
Vaccination of companion animals to elicit a protective immune response against tick infestations and tick-borne pathogen transmission
Compositions of either the aquaporin protein from the cattle tick, rhipicephalus microplus, or a nucleic acid construct incorporating a nucleic acid sequence encoding this aquaporin protein, are effective for eliciting a protective immune response against other tick species in non-bovine animals. The r.
09/18/14
20140271698
Porcine reproductive and respiratory syndrome virus, compositions, vaccine and methods of use
The present invention relates to porcine reproductive and respiratory syndrome virus (prrsv) mutant strains having increased stability; compositions containing the strains or antigens derived therefrom; vaccines containing the strains, including killed, attenuated or subunit vaccines; nucleic acids encoding prrsv polypeptides, polypeptides encoded by the nucleic acids, including antigenic fragments thereof; antibodies which specifically bind to said polypeptides, and methods making and using thereof.. .
09/18/14
20140271691
Therapeutic cancer vaccine targeted to haah (aspartyl-[asparaginyl]-beta-hydroxylase)
The present invention encompasses a cancer vaccine therapy targeting aspartyl-[asparaginyl]-β-hydroxylase (haah). The present invention contemplate bacteriophage expressing haah peptide fragments and methods for using said bacteriophage in methods of treating cancer..
09/18/14
20140271690
Peptide vaccine for prevention and immunotherapy of dementia of the alzheimer's type
The present disclosure is directed to individual aβ peptide immunogen constructs, peptide compositions comprising these aβ peptide immunogen constructs and mixtures thereof, pharmaceutical compositions including vaccine formulations comprising these aβ peptide immunogen constructs, with the individual aβ peptide immunogen constructs having the n-terminus of the aβ peptide as the b cell (b) epitopes linked through spacer residue(s) to heterologous t helper cell (th) epitopes derived from pathogen proteins that act together to stimulate the generation of highly specific antibodies directed against the n-terminus of the aβ peptide offering protective immune responses to patients at risk for, or with, alzheimer's disease.. .
09/18/14
20140271689
Therapeutic cancer vaccine targeted to haah (aspartyl-[asparaginyl]-beta-hydroxylase)
The present invention encompasses a cancer vaccine therapy targeting aspartyl-[asparaginyl]-β-hydroxylase (haah). The present invention contemplate bacteriophage expressing haah peptide fragments and methods for using said bacteriophage in methods of treating cancer..
09/18/14
20140271563
Effect of an attenuated bordetella strain against allergic disease
Described herein are compositions, vaccines, and methods that include use of a mutated bordetella strain against allergic diseases such as asthma and skin inflammation. Also described are kits.
09/11/14
20140256922
Toll-like receptor-7 and -8 modulatory 1h imidazoquinoline derived compounds
The present disclosure provides novel imidazoquinoline derived compounds, derivatives thereof, analogues thereof, and pharmaceutically acceptable salts thereof, and methods of making and using such compounds. The present disclosure also provides tlr7 agonists and tlr7/tlr8 dual agonists, probes, tissue-specific molecules, adjuvants, immunogenic compositions, therapeutic compositions, and self-adjuvanting vaccines including the imidazoquinoline derived compounds, derivatives thereof, analogues thereof, and pharmaceutically acceptable salts thereof.
09/11/14
20140256648
Hjurp peptides and vaccines including the same
Isolated peptides derived from seq id no: 50 and fragments thereof that bind to an hla antigen and induce cytotoxic t lymphocytes (ctl) and thus are suitable for use in cancer immunotherapy are described herein. The inventive peptides encompass both the above mentioned amino acid sequences and modified versions thereof, provided they retain the requisite cytotoxic t cell inducibility of the original sequence.
09/11/14
20140255447
Production of avian embryo cells
The present invention relates to compositions and methods for preparing cells from avian embryos. The invention also relates to cultures of such cells and the uses thereof, particularly for producing viruses such as mdv.
09/11/14
20140255445
Synthetic viruses and uses thereof
The present invention relates to compositions and methods for producing an immune response or reaction, as well as to vaccines, kits, processes, cells and uses thereof. This invention more particularly relates to compositions and methods of using a synthetic viral particle to produce, modify or regulate an immune response in a subject.
09/11/14
20140255442
Novel european prrsv strain
The present invention is related to improved modified live prrs vaccines containing new prrsv european strains of prrsv and methods of use and manufacture of such vaccines.. .
09/11/14
20140255439
Virus-like particles and process for preparing same
An in vitro process of preparing virus-like particles (vlps) from recombinant papaya mosaic virus coat protein and ssrna, which allows for large scale production of vlps in high yields, is provided. Also provided are vlps comprising ssrna prepared by the in vitro process.
09/11/14
20140255437
Topk peptides and vaccines including the same
The present invention provides isolated epitope peptides derived from topk and immunogenic fragments thereof have an ability to induce cytotoxic t lymphocytes (ctls) and thus are suitable for use in cancer immunotherapy, more particularly as cancer vaccines. The peptides of the present invention encompass both of peptides including a topk-derived amino acid sequence and modified versions thereof, in which one, two, or several amino acids are substituted, deleted, inserted and/or added, provided such modified versions have ctl inducibility.
09/11/14
20140255343
Dna vaccine, method of inducing the immune response, method of immunisation, antibodies specifically recognising the h5 haemagglutinin of an influenza virus and use of the dna vaccine
The object of the invention is a dna vaccine, method of inducing the immune response, antibodies specifically recognising the haemagglutinin h5 of an influenza virus and application of the dna vaccine. According to the invention, one or two-fold immunisation of hens with dna vaccine containing a cdna encoding the modified h5 haemagglutinin ha protein, i.e.
09/04/14
20140249467
Cross-protective arenavirus vaccines and their method of use
The invention relates to dna vaccines that target multiple arenavirus agents singly or simultaneously.. .
09/04/14
20140248640
Methods for testing an immune response using cultures of t cells, b cells, dendritic cells and follicular dendritic cells
The present invention relates to methods for preparing an artificial immune system. The artificial immune system comprises a cell culture comprising t cells, b cells and antigen-primed dendritic cells.
09/04/14
20140248360
Nanoparticle tumour vaccines
The present invention provides a vaccine for the prophylactic or therapeutic treatment of a tumour in a mammalian subject, as well as methods of using the vaccine, including in treatment of tumours and in generating a ctl response. The vaccine comprises a plurality of nanoparticles and a pharmaceutically acceptable carrier, salt or diluents.
09/04/14
20140248354
Controlled release vaccines and methods for treating brucella diseases and disorders
Methods and compositions for the treatment of brucella induced diseases and disorders are disclosed herein. In preferred embodiments, the invention relates to vaccines.
09/04/14
20140248337
Liposomal vaccine compositions comprising a polysaccharide antigen and a protein adjuvant
A liposomal composition, preferably a vaccine, comprising liposomes formed of liposome forming compounds, containing coentrapped polysaccharide antigen and t-cell dependent protein carrier, such as tetanus toxoid or diphtheria toxin modified to render it non-toxic. The invention is of use in the production of vaccines against haemophilus influenzae, streptococcus pneumoniae or neisseria meningitidis..
09/04/14
20140248320
Adjuvanted influenza b virus vaccines for pediatric priming
The influenza b strain is epidemiologically relevant in the pediatric population. Immunogenic priming of children with influenza b vaccine adjuvanted with an oil-in-water emulsion primes an immune response to a booster vaccine comprising influenza b virus antigen from a different strain or lineage, irrespective of whether the booster comprises an adjuvant..
09/04/14
20140248312
Influenza vaccines including combinations of particulate adjuvants and immunopotentiators
Influenza vaccines containing insoluble particulate adjuvants have been found to elicit an igg response that is primarily a th2 response (igg1). This response can be shifted towards a th1 response (igg2a) by including immunopotentiators in the compositions.
09/04/14
20140248310
Cationic metal oxides for use as vaccine adjuvants
Adjuvant and immunological vaccine compositions comprising modified, cationic metal oxides are disclosed, including methods of making modified, cationic metal oxides and methods of using the modified metal oxides in vaccine formulations and regimens.. .
09/04/14
20140248309
Dna promoters and anthrax vaccines
The invention is related to intracellularly induced bacterial dna promoters and vaccines against bacillus anthracis.. .
09/04/14
20140248305
Adenoviral vectors comprising partial deletions of e3
This disclosure provides replication-incompetent adenoviral vectors useful in vaccine development and gene therapy. The disclosed vectors comprise a selective deletion of e3 and are particularly useful for preparation of vaccines development and for gene therapy using toxic transgene products that result in vector instability that occurs when the entire e3 domain is deleted..
09/04/14
20140248303
Synthetic streptococcus pneumoniae vaccine
Compositions and methods for preventing and treating pneumococcal infections are provided. Compositions include novel polypeptides comprising an amino acid sequence corresponding to the r21 or r22 domain of cbpa or a consensus sequence of one of these domains, and variants and fragments thereof, wherein the polypeptide is stabilized in a desired conformation, particularly a loop conformation.
09/04/14
20140248300
Peptide vaccines for cancers expressing tumor-associated antigens
The present invention provides peptides having an amino acid sequence as set forth in seq id no: 19, 22, 30, 34, 344, 358, 41, 44, 46, 48, 78, 376, 379, 80, 100, 101, 110, 111, 387, 112, 394, 114, 116, 117, 121, 395, 133, 135, 137, 426, 143, 147, 148, 149, 150, 152, 153, 154, 156, 160, 161, 162, 163, 166, 174, 178, 186, 194, 196, 202, 210, 213, 214, 217, 223, 227, 228, 233, 254, 271, 272 or 288, as well as peptides having the above-mentioned amino acid sequences in which 1, 2, or several (e.g., up to 5) amino acids are substituted, deleted, or added, provided the peptides possess cytotoxic t cell inducibility. The present invention also provides drugs for treating or preventing a disease associated with over-expression of the cdh3, epha4, ect2, hig2, inhbb, kif20a, kntc2, ttk and/or urlc10, e.g.
09/04/14
20140248273
Vaccine based on staphylococcal superantigen-like 3 protein (ssl3)
The present invention relates to the field of vaccinology, especially of vaccines against staphylococcus aureus, for both human and veterinary application. In particular the invention relates to a staphylococcal superantigen-like 3 (ssl3) protein or its homolog, an immunogenic fragment of either protein, for use in a vaccine against s.
09/04/14
20140248272
Recombinant proteins for use in vaccine, antibodies against said proteins, and diagnostic and therapeutic methods including the same
The present invention relates to proteins and/or fragments and derivatives thereof and their use as vaccines and in biotechnological methods. The vaccines particularly include immunogenic proteins in treponema spp.
09/04/14
20140248211
Method of treating cancer
The invention provides a method for treating cancer using a coadministration strategy that combines local codelivery of a therapeutic agent and an intracellular penetration enhancing agent, and optionally in further combination with local administration of an immunotherapeutic agent, such as a cancer vaccine or nkt agonist. The invention also provides a method for treating cancer using an intracellular penetration enhancing agent.


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This listing is a sample listing of patent applications related to Vaccine for is only meant as a recent sample of applications filed, not a comprehensive history. There may be associated servicemarks and trademarks related to these patents. Please check with patent attorney if you need further assistance or plan to use for business purposes. This patent data is also published to the public by the USPTO and available for free on their website. Note that there may be alternative spellings for Vaccine with additional patents listed. Browse our RSS directory or Search for other possible listings.
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