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Uterine Fibroids

Uterine Fibroids-related patent applications - as published by the U.S. Patent and Trademark Office (USPTO).


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Selective androgen receptor degrader (sard) ligands and methods of use thereof
University Of Tennessee Research Foundation
June 15, 2017 - N°20170166526

This invention provides novel indole, indazole, benzimidazole, indoline, quinolone, isoquinoline, and carbazole selective androgen receptor degrader (sard) compounds, pharmaceutical compositions and uses thereof in treating prostate cancer, advanced prostate cancer, castration resistant prostate cancer, other ar-expressing cancers, androgenic alopecia or other hyper androgenic dermal diseases, kennedy's disease, amyotrophic lateral sclerosis (als), abdominal aortic aneurysm (aaa), and uterine fibroids, and to ...
Selective androgen receptor degrader (sard) ligands and methods of use thereof
University Of Tennessee Research Foundation
May 18, 2017 - N°20170137374

This invention provides novel 3-amino propanamide selective androgen receptor degrader (sard) compounds, pharmaceutical compositions and uses thereof in treating prostate cancer, advanced prostate cancer, castration resistant prostate cancer, androgenic alopecia or other hyperandrogenic dermal diseases, kennedy's disease, amyotrophic lateral sclerosis (als), and uterine fibroids, and to methods for reducing the levels of androgen receptor-full length (ar-fl) including pathogenic or resistance ...
Selective androgen receptor degrader (sard) ligands and methods of use thereof
University Of Tennessee Research Foundation
April 06, 2017 - N°20170095446

This invention provides novel indole, indazole, benzimidazole, indoline, quinolone, isoquinoline, and carbazole selective androgen receptor degrader (sard) compounds, pharmaceutical compositions and uses thereof in treating prostate cancer, advanced prostate cancer, castration resistant prostate cancer, androgenic alopecia or other hyper androgenic dermal diseases, kennedy's disease, amyotrophic lateral sclerosis (als), and uterine fibroids, and to methods for reducing the levels of androgen ...
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Selective androgen receptor degrader (sard) ligands and methods of use thereof
University Of Tennessee Research Foundation
February 23, 2017 - N°20170050921

This invention provides novel 3-amino propanamide selective androgen receptor degrader (sard) compounds, pharmaceutical compositions and uses thereof in treating prostate cancer, advanced prostate cancer, castration resistant prostate cancer, androgenic alopecia or other hyperandrogenic dermal diseases, kennedy's disease, amyotrophic lateral sclerosis (als), and uterine fibroids, and to methods for reducing the levels of androgen receptor-full length (ar-fl) including pathogenic or resistance ...
Selective androgen receptor degrader (sard) ligands and methods of use thereof
University Of Tennessee Research Foundation
February 02, 2017 - N°20170029370

This invention provides novel indole, indazole, benzimidazole, indoline, quinolone, isoquinoline, and carbazole selective androgen receptor degrader (sard) compounds, pharmaceutical compositions and uses thereof in treating prostate cancer, advanced prostate cancer, castration resistant prostate cancer, other ar-expressing cancers, androgenic alopecia or other hyper androgenic dermal diseases, kennedy's disease, amyotrophic lateral sclerosis (als), abdominal aortic aneurysm (aaa), and uterine fibroids, and to ...
System and method for three-dimensional quantitative evaluaiton of uterine fibroids
Koninklijke Philips N.v.
November 17, 2016 - N°20160335770

A system (100) and method which assess the results of uterine fibroid embolization. A fibroid lesion is three-dimensionally segmented by a segmentation module (110) on contrast-enhanced arterial phase mri or cbct images and a differentiation process performed by a subtraction module (114) identifies actual contrast enhancement from background enhancement. The three-dimensional segmentation mask is then applied to the differentiated image and a region ...
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Progesteron receptor modulators for use in the therapy of uterine fibroids
Preglem Sa
February 11, 2016 - N°20160038510

The present invention relates to a long-term therapy including repeated treatment courses of ulipristal acetate or any metabolite thereof for treating uterine fibroids. The present invention also relates to a combined therapy applying ulipristal acetate with a progestin in order to improve the currently used treatment for uterine fibroids.
Method for treating uterine fibroids
The Usa, As Represented By The Secretary, Dept. Of Health And Human Services
January 28, 2016 - N°20160022698

The invention relates to a method for treating uterine fibroids, which method comprises administering to a patient in need thereof, an effective amount of 17α-acetoxy-11β-[4-n,n-dimethylamino-phenyl)-19-norpregna-4,9-diene-3,20-dione (ulipristal) or any metabolite thereof. More particularly, the method is useful for reducing or stopping bleeding in a patient afflicted with uterine fibroids, and/...
Herbal composition and a method of treating uterine fibroids
Kang Li Biotech Co., Ltd.
January 07, 2016 - N°20160000846

The invention discloses an herbal composition of treating uterine fibroid. The herbal composition comprises antrodia cinnamomea, astragalus membranaceus, and leonurus japonicus; wherein the weight percentages of antrodia cinnamomea, astragalus membranaceus and leonurus japonicus are 25 to 75%, 20. 8 to 62. 5% and 4. 2 to 12. 5% by weight of the formula, respectively. The invention also discloses a method of treating uterine fibroid.
Fsh receptor antagonists
Kang Li Biotech Co., Ltd.
November 19, 2015 - N°20150329545

Or a pharmaceutically acceptable salt thereof and to a pharmaceutical composition containing the same. The compounds can be used for the treatment and prevention of endometriosis, for the treatment and prevention of pre-menopausal and peri-menopausal hormone-dependent breast cancer, for contraception, and for the treatment of uterine fibroids and other menstrual-related disorders.
Modified release osmotic pump for ph-responsive drug delivery
University Of Utah Research Foundation
November 12, 2015 - N°20150320675

In one aspect, the invention relates to controlled-release devices and methods of using same, alone or in combination with other agents, to deliver pharmaceutical agents, and more particularly to deliver birth control agent, fertility agents, hormone replacement agents, cervical ripening agents, agents to prevent a sexually transmitted disease, agents to treat a sexually transmitted disease, biologics, agents to treat a ...
Methods and compositions for treating progesterone-dependent conditions
Repros Therapeutics Inc.
October 22, 2015 - N°20150297612

The subject matter of the instant invention is pertinent to the field of treatment of hormone-dependent conditions. Methods for treating these conditions are provided comprising systemically administering an antiprogestin and contemporaneously locally administering an antiprogestin. Embodiments of the instant invention disclose methods for treating endometriosis, dysmenorrhea, breast cancer, uterine fibroids and endometrial hyperproliferation.
Novel 19-nor-steroids and their use for treating progesterone- dependent conditions
Repros Therapeutics Inc.
July 23, 2015 - N°20150203526

The subject matter of the instant invention is pertinent to the field of treatment of hormone-dependent conditions. New compounds and methods for treating these conditions are disclosed. Embodiments of the instant invention disclose methods for treating endometriosis, dysmenorrhea, breast cancer, uterine fibroids and endometrial hyperproliferation.
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Bipolar coagulation probe and snare
Gyrus Acmi, Inc.
April 02, 2015 - N°20150094719

An electrosurgical device that can be used to remove pedunculated tissue structures such as polyps and certain uterine fibroids includes bipolar surface electrodes and a bipolar snare. The device includes a probe having a proximal end and a distal end, bipolar surface electrodes adjacent to the distal end of the probe, and a bipolar snare extending distally from the distal ...
Method of thermal treatment for myolysis and destruction of benign uterine tumors
The Regents Of The University Of California
January 15, 2015 - N°20150018727

A high-power ultrasound heating applicator for minimally-invasive thermal treatment of uterine fibroids or myomas. High-intensity interstitial ultrasound, applied with minimally-invasive laparoscopic or hysteroscopic procedures, is used to effectively treat fibroids within the myometrium in lieu of major surgery. The applicators are configured with high-power capabilities and thermal penetration to treat large volumes of fibroid tissue (>70 cm3) in short ...
Treatment of uterine fibroids by arterial ablation
Gyrus Acmi, Inc., D.b.a. Olympus Surgical Technologies America
December 25, 2014 - N°20140378963

Methods and apparatus for ablating blood vessels in treatment of uterine fibroids. A monopolar electrode provided on a needle probe is positioned in an artery supplying blood to a uterine fibroid. Energy is supplied to the electrode to ablate the artery. In this way, the uterine fibroid and the surrounding tissues remain relatively undamaged, and the uterine fibroid, deprived of ...
Spiroindoline derivatives as gonadotropin- releasing hormone receptor antagonists
Gyrus Acmi, Inc., D.b.a. Olympus Surgical Technologies America
December 04, 2014 - N°20140357655

Spiroindoline derivatives, process for their preparation and pharmaceutical compositions thereof, their use for the treatment and/or prophylaxis of diseases, and their use for the manufacture of medicaments for the treatment and/or prophylaxis of diseases, especially sex-hormone-related diseases in both men and women, in particularly those selected from the group of endometriosis, uterine fibroids, polycystic ovarian disease, hirsutism, precocious ...
Organic compounds
Gyrus Acmi, Inc., D.b.a. Olympus Surgical Technologies America
December 04, 2014 - N°20140357621

Said compound is inhibitor of aldosterone synthase and aromatase, and thus can be employed for the treatment of a disorder or disease mediated by aldosterone synthase or aromatase. Accordingly, the compound of formula i can be used in treatment of hypokalemia, hypertension, congestive heart failure, atrial fibrillation, renal failure, in particular, chronic renal failure, restenosis, atherosclerosis, syndrome x, obesity, nephropathy, ...
Fsh receptor antagonists
Gyrus Acmi, Inc., D.b.a. Olympus Surgical Technologies America
November 27, 2014 - N°20140350043

The invention relates to fsh receptor antagonist according to general formula (i) or a pharmaceutically acceptable salt thereof and to a pharmaceutical composition containing the same. The compounds can be used for the treatment and prevention of endometriosis, for the treatment and prevention of pre-menopausal and peri-menopausal hormone-dependent breast cancer, for contraception, and for the treatment of uterine fibroids and ...
N-piperidin-4-yl derivatives
Gyrus Acmi, Inc., D.b.a. Olympus Surgical Technologies America
November 06, 2014 - N°20140329822

The invention relates to a n-piperidin-4-yl derivative having the general formula i or a pharmaceutically acceptable salt thereof, to pharmaceutical compositions comprising the same and to the use of said n-piperidin-4-yl derivatives for the treatment and prevention of endometriosis, for the treatment and prevention of pre-menopausal and peri-menopausal hormone-dependent breast cancer, for contraception, or for the treatment of ...
Intrauterine system for use in medical treatment
Gyrus Acmi, Inc., D.b.a. Olympus Surgical Technologies America
October 02, 2014 - N°20140296833

An intrauterine system is disclosed for use in the treatment of dysfunctional uterine bleeding; menorraghia; dysmenorrhoea; endometriosis; uterine fibroids; climacteric complaints; osteoporosis; and urogenital atrophy. The system is formed by a frame defining an interior space for receipt of a deposit of a therapeutically effective dose of a biologically active compound. The frame has an open structure allowing access to ...
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