Images List Premium Download Classic

Treprostinil

Treprostinil-related patent applications - as published by the U.S. Patent and Trademark Office (USPTO).


loading
Salts of treprostinil
United Therapeutics Corporation
September 21, 2017 - N°20170267619

Provided are novel treprostinil salts as well as methods for making treprostinil salts.
Synthesis of intermediate for treprostinil production
United Therapeutics Corporation
July 13, 2017 - N°20170197898

The compound according to formula i is an intermediate in the synthesis of prostacylin analogs. The present invention provides an efficient method for synthesizing a formula i compound.
Process to prepare treprostinil, the active ingredient in remodulin®
United Therapeutics Corporation
June 29, 2017 - N°20170181990

This present invention relates to an improved process to prepare prostacyclin derivatives. One embodiment provides for an improved process to convert benzindene triol to treprostinil via salts of treprostinil and to purify treprostinil.
Treprostinil Patent Pack
Download + patent application PDFs
Treprostinil Patent Applications
Download + Treprostinil-related PDFs
For professional research & prior art discovery
inventor
  • + full patent PDF documents of Treprostinil-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
Process to prepare treprostinil, the active ingredient in remodulin®
United Therapeutics Corporation
May 25, 2017 - N°20170144958

This present invention relates to an improved process to prepare prostacyclin derivatives. One embodiment provides for an improved process to convert benzindene triol to treprostinil via salts of treprostinil and to purify treprostinil.
Process to prepare treprostinil, the active ingredient in remodulin®
United Therapeutics Corporation
May 25, 2017 - N°20170144957

This present invention relates to an improved process to prepare prostacyclin derivatives. One embodiment provides for an improved process to convert benzindene triol to treprostinil via salts of treprostinil and to purify treprostinil.
Treprostinil formulations
United Therapeutics Corporation
April 06, 2017 - N°20170095432

Provided are ion complexes comprising treprostinil and an ion-exchange resin, pharmaceutical formulations based on such complexes, and methods of treating diseases and conditions using the ion complexes and pharmaceutical formulations.
Treprostinil Patent Pack
Download + patent application PDFs
Treprostinil Patent Applications
Download + Treprostinil-related PDFs
For professional research & prior art discovery
inventor
  • + full patent PDF documents of Treprostinil-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
Salts of treprostinil
United Therapeutics Corporation
March 16, 2017 - N°20170073295

Provided are novel treprostinil salts as well as methods for making treprostinil salts.
Rapid-acting insulin compositions
Eli Lilly And Company
March 02, 2017 - N°20170056478

The invention is a pharmaceutical composition of human insulin or insulin analog that includes citrate, treprostinil and stabilizing agents, that has faster pharmacokinetic and/or pharmacodynamic action than commercial formulations of existing insulin analog products and that is stable for commercial use.
Prostacyclin compounds, compositions and methods of use thereof
Insmed Incorporated
February 23, 2017 - N°20170049739

Prostacyclin compounds and compositions comprising the same are provided herein. Specifically, prostacyclin compounds comprising treprostinil covalently linked to a linear c5-c18 alkyl, branched c5-c18 alkyl, linear c2-c18 alkenyl, branched c3-c18 alkenyl, aryl, aryl-c1-c18 alkyl or an amino acid or a peptide (e. G., dipeptide, tripeptide, tetrapeptide) are described. The linkage, in one embodiment, is via ...
Treprostinil derivative compounds and methods of using same
Corsair Pharma, Inc.
December 22, 2016 - N°20160368889

Compounds represented by formulae i, ii, iii, and iv including pro-drugs for treprostinil and prostacyclin analogs. Uses include treatment of pulmonary hypertension (ph) or pulmonary arterial hypertension (pah). The structures of the compounds can be adapted to the particular application for a suitable treatment dosage. Transdermal applications can be used.
Treprostinil derivatives and compositions and uses thereof
Corsair Pharma, Inc.
December 22, 2016 - N°20160368855

The present disclosure provides treprostinil derivatives that can act as prodrugs of treprostinil. The treprostinil derivatives can be used to treat any conditions responsive to treatment with treprostinil, including pulmonary hypertension, such as pulmonary arterial hypertension.
Treprostinil derivatives and compositions and uses thereof
Corsair Pharma, Inc.
December 22, 2016 - N°20160368854

The present disclosure provides treprostinil derivatives that can act as prodrugs of treprostinil. The treprostinil derivatives can be used to treat any conditions responsive to treatment with treprostinil, including pulmonary hypertension, such as pulmonary arterial hypertension.
Rapid-acting insulin compositions
Eli Lilly And Company
December 22, 2016 - N°20160367640

The invention is a composition of human insulin or insulin analog that includes treprostinil and that has faster pharmacokinetic action than commercial formulations of existing insulin analog products.
Treprostinil Patent Pack
Download + patent application PDFs
Treprostinil Patent Applications
Download + Treprostinil-related PDFs
For professional research & prior art discovery
inventor
  • + full patent PDF documents of Treprostinil-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
Prostacyclin compounds, compositions and methods of use thereof
Insmed Incorporated
September 08, 2016 - N°20160256425

Prostacyclin compounds and compositions comprising the same are provided herein. Specifically, prostacyclin compounds comprising treprostinil covalently linked to a linear c5-c18 alkyl, branched c5-c18 alkyl, linear c2-c18 alkenyl, branched c3-c18 alkenyl, aryl, aryl-c1-c18 alkyl or an amino acid or a peptide (e. G., dipeptide, tripeptide, tetrapeptide) are described. The linkage, in one embodiment, is via ...
Novel oral pharmaceutical compositions of treprostinil
Gavis Pharmaceuticals
August 25, 2016 - N°20160243064

Oral pharmaceutical compositions of treprostinil, a prodrug, or a pharmaceutically acceptable salt thereof are provided. The compositions possess absolute oral bioavailability of greater than 10% and achieve circulating concentrations when administered orally. Methods of treating prostacyclin responsive conditions including pulmonary arterial hypertension (pah) by administering such compositions also are provided.
Device for treating a cutaneous ulcer
Gavis Pharmaceuticals
June 09, 2016 - N°20160158543

A dc generator, the terminals of which are connected to the electrodes, the cathode and the anode respectively forming the active electrode and the passive electrode for iontophoresis, so as to cause treprostinil to migrate by cathodal iontophoresis into the region to be treated.
Treprostinil administration by inhalation
United Therapeutics Corporation
May 26, 2016 - N°20160143868

Treprostinil can be administered using a metered dose inhaler. Such administration provides a greater degree of autonomy to patients. Also disclosed are kits that include a metered dose inhaler containing a pharmaceutical formulation containing treprostinil.
Rapid-acting insulin compositions
Eli Lilly And Company
May 12, 2016 - N°20160129087

The invention is a composition of human insulin or insulin analog that includes treprostinil and that has faster pharmacokinetic action than commercial formulations of existing insulin analog products.
Synthesis of intermediates for producing prostacyclin derivatives
Eli Lilly And Company
April 21, 2016 - N°20160107973

The present disclosure provides regioselective methods for synthesizing intermediates useful in making prostacyclin derivatives, such as treprostinil.
Synthesis of intermediate for treprostinil production
United Therapeutics Corporation
March 10, 2016 - N°20160068461

The compound according to formula i is an intermediate in the synthesis of prostacylin analogs. The present invention provides an efficient method for synthesizing a formula i compound.
Loading