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Treprostinil topics
Treprostinil
Prostacyclin
Atherogenesis
Platelet Aggregation
Lung Disease
Vasodilation
Cell Proliferation
Proliferation
Angiogenesis
Benzaldehyde
Pharmaceutically Acceptable Salt
Pulmonary Fibrosis
Interstitial
Metered Dose Inhaler

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Treprostinil patents



      
           
This page is updated frequently with new Treprostinil-related patent applications. Subscribe to the Treprostinil RSS feed to automatically get the update: related Treprostinil RSS feeds. RSS updates for this page: Treprostinil RSS RSS


Date/App# patent app List of recent Treprostinil-related patents
10/02/14
20140296150
 Carrier-linked treprostinil prodrugs patent thumbnailCarrier-linked treprostinil prodrugs
The present invention relates to prodrugs or a pharmaceutically acceptable salt thereof comprising a covalent treprostinil carrier conjugate as well as pharmaceutical composition comprising said compounds. The compounds may be used as medicaments, especially for diseases or disorders which can be treated by treprostinil, such as pulmonary arterial hypertension (pah)..
09/25/14
20140288179
 Stable solutions of treprostinil patent thumbnailStable solutions of treprostinil
An improved method for administering treprostinil or a salt is described that allows for use of the diluted solution prior to administration for a longer period of time to avoid wasted medication.. .
09/18/14
20140275616
 Salts of treprostinil patent thumbnailSalts of treprostinil
Provided are novel treprostinil salts as well as methods for making treprostinil salts.. .
09/18/14
20140275262
 Solid forms of treprostinil patent thumbnailSolid forms of treprostinil
There is provided individual polymorphic forms of treprostinil and pharmaceutical formulations comprising the same, methods of making and using the same. .
09/11/14
20140256730
 Treprostinil derivative compounds and methods of using same patent thumbnailTreprostinil derivative compounds and methods of using same
Compounds represented by formulae i, ii, iii, and iv including pro-drugs for treprostinil and prostacyclin analogs. Uses include treatment of pulmonary hypertension (ph) or pulmonary arterial hypertension (pah).
01/23/14
20140024856
 Process for treprostinil salt preparation patent thumbnailProcess for treprostinil salt preparation
Disclosed is a process for preparing a treprostinil salt. The process involves the step of dissolving treprostinil in a water-miscible organic solvent to form a treprostinil solution.
01/16/14
20140018431
 Treprostinil treatment for interstitial lung disease and asthma patent thumbnailTreprostinil treatment for interstitial lung disease and asthma
The present invention describes methods for using treprostinil or its derivative, or a pharmaceutically acceptable salt thereof, for the treatment and/or prevention of interstitial lung disease or asthma, or a condition, such as pulmonary fibrosis, associated with interstitial lung disease or a condition associated with asthma. The invention also relates to kits for treatment and/or prevention of such condition that include an effective amount of treprostinil or its derivative, or a pharmaceutically acceptable salt thereof..
12/26/13
20130345471
 Synthesis of intermediate for treprostinil production patent thumbnailSynthesis of intermediate for treprostinil production
The compound according to formula i is an intermediate in the synthesis of prostacylin analogs. The present invention provides an efficient method for synthesizing a formula i compound..
12/12/13
20130331593
 Synthesis of treprostinil and intermediates useful therein patent thumbnailSynthesis of treprostinil and intermediates useful therein
Treprostinil is prepared by a process which involves pauson-khan cyclization of an an alkene-substituted, alkyne-substituted benzene corresponding to formula: (i) where pmb represents para-methoxy benzyl protecting group and r1 and r2 are alcohol protecting groups. Following cyclization, the resulting compound can be subjected to several chemical trans-formations followed by alkylation, hydrolysis and salt formation to yield treprostinil sodium.
10/31/13
20130289304
 Process to prepare treprostinil, the active ingredient in remodulin® patent thumbnailProcess to prepare treprostinil, the active ingredient in remodulin®
This present invention relates to an improved process to prepare prostacyclin derivatives. One embodiment provides for an improved process to convert benzindene triol to treprostinil via salts of treprostinil and to purify treprostinil..
10/10/13
20130267734
Process to prepare treprostinil, the active ingredient in remodulin®
This present invention relates to an improved process to prepare prostacyclin derivatives. One embodiment provides for an improved process to convert benzindene triol to treprostinil via salts of treprostinil and to purify treprostinil..
10/03/13
20130261187
Compounds and methods for delivery of prostacyclin analogs
This invention pertains generally to prostacyclin analogs and methods for their use in promoting vasodilation, inhibiting platelet aggregation and thrombus formation, stimulating thrombolysis, inhibiting cell proliferation (including vascular remodeling), providing cytoprotection, preventing atherogenesis and inducing angiogenesis. Generally, the compounds and methods of the present invention increase the oral bioavailability and circulating concentrations of treprostinil when administered orally.
08/15/13
20130211145
Protected aldehydes for use as intermediates in chemical syntheses, and processes for their preparation
A para-methoxy protected benzaldehyde useful in preparation of treprostinil, and of formula: (formula (1)) is prepared by subjecting to claisen re-arrangement a substituted benzaldehyde of formula (1a): (formula (ia)) to form the m-hydroxy-substituted benzaldehyde of formula (1b): (formula (ib)) and then reacting compound (1b) with a p-methoxybenzyl (pmb) compound to form a pmb-substituted benzaldehyde of formula (1).. .
04/18/13
20130096200
Treprostinil treatment for interstitial lung disease and asthma
The present invention describes methods for using treprostinil or its derivative, or a pharmaceutically acceptable salt thereof, for the treatment and/or prevention of interstitial lung disease or asthma, or a condition, such as pulmonary fibrosis, associated with interstitial lung disease or a condition associated with asthma. The invention also relates to kits for treatment and/or prevention of such condition that include an effective amount of treprostinil or its derivative, or a pharmaceutically acceptable salt thereof..


Popular terms: [SEARCH]

Treprostinil topics: Treprostinil, Prostacyclin, Atherogenesis, Platelet Aggregation, Lung Disease, Vasodilation, Cell Proliferation, Proliferation, Angiogenesis, Benzaldehyde, Pharmaceutically Acceptable Salt, Pulmonary Fibrosis, Interstitial, Metered Dose Inhaler

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This listing is a sample listing of patent applications related to Treprostinil for is only meant as a recent sample of applications filed, not a comprehensive history. There may be associated servicemarks and trademarks related to these patents. Please check with patent attorney if you need further assistance or plan to use for business purposes. This patent data is also published to the public by the USPTO and available for free on their website. Note that there may be alternative spellings for Treprostinil with additional patents listed. Browse our RSS directory or Search for other possible listings.
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