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Transplant

Transplant-related patent applications - as published by the U.S. Patent and Trademark Office (USPTO).


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NEW Method for treating antibody-mediated rejection post-transplantation
Cedars-sinai Medical Center
June 22, 2017 - N°20170174760

Described herein are methods for treating antibody mediated rejection of transplanted organs using inhibitors of il-6. In one embodiment, the il-6 inhibitor is tocilizumab and is administered simultaneously or sequentially with intravenous immunoglobulin (ivig).
NEW Isolated donor mhc-derived peptide and uses thereof
UniversitÉ De Nantes
June 22, 2017 - N°20170173125

The invention relates to an peptide derived from a polymorphic region of donor mhc class ii molecules which induces tolerance and thus prevents transplant rejection in a patient in need thereof. The invention relates to isolated peptide of length ranging between 11 and 16 amino acids comprising the amino acid sequence: sdvgeyr (seq id no: 1) or a function-conservative variant thereof for use ...
NEW Compositions and methods for ex vivo expansion of human hematopoietic stem/progenitor cells
National University Of Singapore
June 22, 2017 - N°20170173083

Described herein are methods and compositions which lead to the efficient ex vivo expansion of hematopoietic cells, such as hematopoietic stem cells (hscs) and hematopoietic stem and progenitor cells hspcs. Using combinations of small molecule drugs and cytokines/growth factors/grown factors targeting epigenetic status in cells, significant improvements in the expansion of cells was observed, including cells isolated from ...
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Transplant Patent Applications
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  • 296+ full patent PDF documents of Transplant-related inventions.
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Multimarker risk stratification
Critical Care Diagnostics, Inc.
June 15, 2017 - N°20170169179

Measurement of circulating st2 and natriuretic peptide (e. G., nt-probnp) concentrations is useful for the prognostic evaluation of subjects, in particular for the prediction of adverse clinical outcomes, e. G., mortality, transplantation, and heart failure.
Peptides for promoting angiogenesis and use thereof
Samsung Life Public Welfare Foundation
June 15, 2017 - N°20170166609

The present invention relates to a peptide promoting angiogenesis and novel use thereof. More particularly, the invention relates to peptides promoting angiogenesis, and the use of the peptide for promoting angiogenesis and preventing or treating angiogenesis-related disease. The peptide of the present invention have an excellent effect on promoting angiogenesis. Accordingly, it is useful for preventing or treating angiogenesis-related disease ...
Gene edited antigen presenting cells
Batu Biologics, Inc.
June 15, 2017 - N°20170165332

Disclosed are cells, compositions of matter, and protocols, useful for stimulation of antigen-specific immunity or tolerogenesis by gene editing of immune suppressive costimulatory molecules for induction of immune stimulation, and gene editing of immune stimulatory molecules for immune suppression. Provided are means of stimulating immunity to cancer, viral antigens, or bacterial antigens through pulsing, fusing, or administering antigenic compositions to ...
Transplant Patent Pack
Download 296+ patent application PDFs
Transplant Patent Applications
Download 296+ Transplant-related PDFs
For professional research & prior art discovery
inventor
  • 296+ full patent PDF documents of Transplant-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
Complexes of sirolimus and its derivatives, process for the preparation thereof and pharmaceutical compositions containing ...
Druggability Technologies Ip Holdco Limited
June 15, 2017 - N°20170165237

The invention is directed to a stable complex with controlled particle size, increased apparent solubility and increased dissolution rate comprising as active compound sirolimus or derivatives thereof, which is useful in the prophylaxis of organ rejection in patients receiving renal transplants, in the treatment of psoriasis, facial angiofibromas associated with tuberous sclerosis, fibrofolliculomas found in birt-hogg-dubé syndrome, chronic erosive ...
A new biomarker of chronic allograft nephropathy and of renal transplant rejection
Fondazione Irccs Ca' Granda Ospedale Maggiore Policlinico
June 08, 2017 - N°20170160290

The invention relates to a method for determining whether a renal transplanted patient is at risk of transplant rejection or can, comprising a step of determining the expression level of the periostin (postn) gene on a renal transplant biopsy obtained from said transplanted patient. The invention also relates to a compound selected from the group consisting of monoclonal anti-cd20 antibodies, ...
Igg subtyping assay for identifying transplantable tissue samples
Nj Sharing Network
June 08, 2017 - N°20170160278

The disclosure relates to methods for assessing the suitability of a tissue obtained from a vertebrate (e. G., human) donor for grafting to a recipient, such as another vertebrate of the same species. The method involves contacting leukocytes obtained from the donor with serum from the recipient. Binding between recipient antibodies and the leukocytes is assessed, specifically focusing on the ...
Tissue modeling in embryonic stem (es) cell system
Axiogenesis Ag
June 08, 2017 - N°20170160259

Provided are embryonic stem (es) cell-derived tissue modeling systems. In particular, systems for the de novo generation of tissue by parallel drug selection of cell types constituting the tissue of interest in one culture of differentiating es cells is described as well as the use of such systems in transplantation and drug development.
Processes for the preparation of (r)-2-(7-(4-cyclopentyl-3-(trifluoromethyl)benzyloxy)-1,2,3,4-tetrahydrocyclopenta[...
Arena Pharmaceuticals, Inc.
June 08, 2017 - N°20170159088

The present invention relates to processes and intermediates useful in the preparation of (r)-2-(7-(4-cyclopentyl-3-(trifluoromethyl)benzyloxy)-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl)acetic acid of formula (ia) and salts thereof, an s1p1 receptor modulator that is useful in the treatment of s1p1 receptor-associated disorders, for example, diseases and disorders mediated by lymphocytes, transplant rejection, ...
Method for producing tissue and organ
Arena Pharmaceuticals, Inc.
June 08, 2017 - N°20170159024

A method of preparing a tissue or an organ, comprising coculturing an organ cell with a vascular endothelial cell and a mesenchymal cell, generating an organ bud, transplanting the organ bud into a non-human animal, and then isolating from the non-human animal the transplanted organ bud-derived tissue or organ.
Method of culturing antrodia cinnamomea with high triterpenoids
Ultra-microrigin Biomedical Technology Co., Ltd.
June 08, 2017 - N°20170159008

A method of culturing antrodia cinnamomea with high triterpenoids includes mixing a malt extract, glucose, peptone, agar, and a mushroom extract with distilled water to obtain a culture medium; providing the culture medium to a high-pressure sterilization machine for sterilization to obtain a sterilized culture medium; providing the sterilized culture medium to an incubator in a disinfection environment to obtain ...
Transplant Patent Pack
Download 296+ patent application PDFs
Transplant Patent Applications
Download 296+ Transplant-related PDFs
For professional research & prior art discovery
inventor
  • 296+ full patent PDF documents of Transplant-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
Tissue transplant compositions and methods for use
Parcell Laboratories Llc
June 08, 2017 - N°20170157291

Provided are transplants and methods for augmenting formation and restoration of organ and tissue, for example, bone formation, by administering autologous or allogeneic human embryonic-like adult stem cells (ela cells). Also provided is a method for augmenting formation of tissues and organs by administering a transplant having ela stem cells or combination of ela stem cells.
Engineering of humanized car t-cell and platelets by genetic complementation
Recombinetics, Inc.
June 01, 2017 - N°20170152526

Human or humanized tissues and organs suitable for transplant are disclosed herein. Gene editing of a host animal provides a niche for complementation of the missing genetic information by donor stem cells. Editing of a host genome to knock out or disrupt genes responsible for the growth and/or differentiation of a target organ and injecting that animal at an ...
Induction of immunotolerance
The Chinese University Of Hong Kong
June 01, 2017 - N°20170151327

The present invention provides for a novel method for inhibiting an undesirable immune response, especially in transplant recipients such as those having received an allogeneic stem cell transplant. Also disclosed are related compositions and kits for inducing immunotolerance.
A novel pharmaceutical composition of sofosbuvir and ribavirin
Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi
June 01, 2017 - N°20170151272

This invention is a novel pharmaceutical composition comprising sofosbuvir and ribavirin as active agents with at least one pharmaceutically acceptable excipient, wherein at least one of the active agents is in the form of controlled release, for use in the treatment of hepatitis c virus infections, chronic hepatitis c, hepatocellular carcinoma or patients with end-stage liver disease awaiting liver transplantation.
Oxygen enhancing membrane systems for implantable devices
Dexcom, Inc.
June 01, 2017 - N°20170150910

The present invention relates generally to systems and methods for increasing oxygen availability to implantable devices. The preferred embodiments provide a membrane system configured to provide protection of the device from the biological environment and/or a catalyst for enabling an enzymatic reaction, wherein the membrane system includes a polymer formed from a high oxygen soluble material. The high oxygen ...
Methods for the treatment of infections and tumors
Dexcom, Inc.
May 25, 2017 - N°20170146520

Pd-1 antagonists are disclosed that can be used to reduce the expression or activity of pd-1 in a subject. An immune response specific to an infectious agent or to tumor cells can be enhanced using these pd-1 antagonists in conjunction with an antigen from the infectious agent or tumor. Thus, subjects with infections, such as persistent infections can be treated ...
Compositions and methods for affecting movement of contaminants, bodily fluids or other entities, and/or ...
Dexcom, Inc.
May 25, 2017 - N°20170143788

Compositions which self-assemble under physiological conditions are formulated for application to wounds. The formulations include a pharmaceutically acceptable carrier or are provided as part of a medical device or coating. The formulations may also include other therapeutic, prophylactic or diagnostic agents. The formulation can be administered as appropriate for treatment of one or more disorders or conditions. For example, the ...
Composition comprising cell and biocompatible polymer
Dexcom, Inc.
May 25, 2017 - N°20170143767

It is an object of the present invention to provide a cell-containing composition capable of suppressing the outflow of the cells after transplantation and improving the survival rate of the cells. The present invention provides a composition which comprises any of bone marrow stromal cell-derived neural precursor cells, bone marrow stromal cell-derived schwann cells, or bone marrow stromal cell-derived skeletal ...
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