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Transplant

Transplant-related patent applications - as published by the U.S. Patent and Trademark Office (USPTO).


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Methods and kits for screening transplant recipients and candidates
National Institute Of Transplantation Foundation
August 17, 2017 - N°20170234875

Methods and kits are provided for determining of immunoglobulin isotypes and subclasses in a subject. In general the subject is a human who is a transplant candidate recipient or recipient, has allergies, or has an autoimmune disease. The method involves analyzing a sample of a body fluid of a transplant candidate or recipient, allergy patient or autoimmune disease sufferer and ...
Anti-cd25 antibodies and their uses
Abbvie Biotherapeutics Inc.
August 17, 2017 - N°20170233481

The present disclosure relates to antibodies directed to cd25 and uses of such antibodies, for example to suppress organ transplant rejection or to treat multiple sclerosis.
Composite bone implants
University Of Leeds
August 17, 2017 - N°20170232145

The invention provides natural multi-composite bone implants such as bone-connective tissue-bone and osteochondral implants for the replacement and/or repair of, for example and in particular a damaged or defective bone-meniscus-bone joint or a bone-patella tendon-bone joint or osteochondral lesions, methods of preparing the composites and uses thereof. The invention also provides natural or native composite bone-connective tissue-bone and osteochondral ...
Transplant Patent Pack
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Transplant Patent Applications
Download 296+ Transplant-related PDFs
For professional research & prior art discovery
inventor
  • 296+ full patent PDF documents of Transplant-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
Electronic phenotyping technique for diagnosing chronic kidney disease
Icahn School Of Medicine At Mount Sinai
August 10, 2017 - N°20170228506

An example method of diagnosing chronic kidney disease (ckd) includes obtaining an electronic medical record for a patient having medical data. The medical data includes an indication if the patient had been previously diagnosed with ckd, an indication if the patient had previously undergone a kidney transplant, an indication if the patient had previously undergone a renal dialysis procedure, an ...
Protein and gene biomarkers for rejection of organ transplants
The Board Of Trustees Of The Leland Stanford Junior University
August 10, 2017 - N°20170227549

Aspects of the present invention include methods for determining a transplant category of a subject having a transplant. Common mechanisms of rejection injury are uncovered across different tissue transplants, and provide a means to understand rational drug design. Various sources of tissues are examined form the patient for understanding ar mechanism (graft biopsy), as well as monitoring by minimal invasive ...
Methods for using exosomes to monitor transplanted organ status
The Trustees Of The University Of Pennsylvania
August 10, 2017 - N°20170227541

This present disclosure relates to the use of donor organ-derived microvesicles to monitor the status of a transplanted organ in a subject. Accordingly, this disclosure provides for methods and kits for isolating, purifying and/or identifying donor organ-derived microvesicles from a biological sample of a subject. In certain embodiments, a method for isolating, purifying and/or identifying donor organ-derived microvesicles ...
Transplant Patent Pack
Download 296+ patent application PDFs
Transplant Patent Applications
Download 296+ Transplant-related PDFs
For professional research & prior art discovery
inventor
  • 296+ full patent PDF documents of Transplant-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
Compositions and methods for epithelial stem cell expansion and culture
Massachusetts Institute Of Technology
August 10, 2017 - N°20170226477

Described are cell culture solutions and systems for epithelial stem cell and organoid cultures, formation of epithelial constructs and uses of the same in transplantation.
Methods for modulating osteochondral development using bioelectrical stimulation
Medrelief Inc.
August 10, 2017 - N°20170226463

Compositions and methods are provided for modulating the growth, development and repair of bone, cartilage or other connective tissue. Devices and stimulus waveforms are provided to differentially modulate the behavior of osteoblasts, chondrocytes and other connective tissue cells to promote proliferation, differentiation, matrix formation or mineralization for in vitro or in vivo applications. Continuous-mode and pulse-burst-mode stimulation of cells with ...
Photoreceptor scaffold for in vitro modeling and transplantation therapy
Wisconsin Alumni Research Foundation
August 10, 2017 - N°20170226459

Photoreceptor scaffolds and scaffold systems including the photoreceptor scaffolds are described herein. The scaffolds and scaffold systems can be used for transplantation of organized photoreceptor tissue, with or without rpe, which may improve grafted cell survival, integration, and functional visual rescue. Particularly, the photoreceptor scaffold is structured from a biocompatible film, patterned with an array of unique through-holes having a ...
Modified alginates for anti-fibrotic materials and applications
The Children's Medical Center Corporation
August 10, 2017 - N°20170226232

Covalently modified alginate polymers, possessing enhanced biocompatibility and tailored physiochemical properties, as well as methods of making and use thereof, are disclosed herein. The covalently modified alginates are useful as a matrix for coating of any material where reduced fibrosis is desired, such as encapsulated cells for transplantation and medical devices implanted or used in the body.
An anti-cd45rc antibody for use as drug
UniversitÉ De Nantes
August 10, 2017 - N°20170226209

The invention relates to an isolated anti-cd45rc antibody for use in preventing or treating transplant rejection, autoimmune diseases, unwanted immune responses against proteins expressed in the course of gene therapy and/or therapeutic proteins, allergy as well as lymphoma or cancer which are associated with cd45rc+ cells. The invention relates to an isolated anti-cd45rc antibody for use ...
Anti-orai1 antibody
Daiichi Sankyo Company, Limited
August 10, 2017 - N°20170226203

It is intended to provide a therapeutic and/or prophylactic agent for transplant rejections, immunological diseases, allergic diseases, inflammatory diseases, thrombosis, cancers, etc., targeting human orai1. The present invention provides, for example, a pharmaceutical composition comprising an antibody that specifically recognizes human orai1 and has the activity of inhibiting human t cell activation.
Methods for preventing transplantation-induced follicle activation
Tel Hashomer Medical Research Infrastructure And Services Ltd.
August 10, 2017 - N°20170224780

Provided are compositions and methods for preventing premature follicle activation and loss induced by transplantation of ovaries or tissues derived from ovaries, thereby preserving fertility in a subject.
Transplant Patent Pack
Download 296+ patent application PDFs
Transplant Patent Applications
Download 296+ Transplant-related PDFs
For professional research & prior art discovery
inventor
  • 296+ full patent PDF documents of Transplant-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
Placental stem cells derived from post-partum mammalian placenta, and uses and methods of treatment using ...
Anthrogenesis Corporation
August 10, 2017 - N°20170224739

The present invention provides compositions and methods of using placental stem cells that originate from a post-partum placenta with conventional cord blood compositions or other stem or progenitor cells. The placental stem cells can be used alone or in a mixture with other stem cell populations. In accordance with the present invention, the placental stem cells may be mixed with ...
Engraftment of stem cells with a combination of an agent that targets stem cells and ...
The Board Of Trustees Of The Leland Stanford Junior Univesity
August 10, 2017 - N°20170224737

The present invention provides a clinically applicable method of stem cell transplantation that facilitates engraftment and reconstitutes immunocompetence of the recipient without requiring radiotherapy or chemotherapy, and without development of gvhd or graft rejection. Aspects of the present invention are based on the discovery that the depletion of the endogenous stem cell niche facilitates efficient engraftment of stem cells into ...
Dual syringe with percutaneous cannula
Adimend Biosciences, Llc
August 10, 2017 - N°20170224318

The dual syringe with percutaneous cannula is a medical device for harvesting and transferring cells for autologous transplantation without the requirement of a surgical setting or ambulatory care. The dual syringe is a closed sterile system that allows for the harvesting syringe to harvest the cells/tissue from a first location of a patient which is then centrifuged to aggregate ...
Apparatus for maintenance of harvested hearts for transplanting
Adimend Biosciences, Llc
August 10, 2017 - N°20170223950

An apparatus, a system, and methods for maintaining and monitoring an excised donor heart. The apparatus comprises a first component for receiving and submerging therein an excised heart in a constantly circulating perfusate solution and a second component comprising equipment for adjusting the temperature and oxygen content of the perfusate solution. The first component comprises an integral pair of defibrillating ...
Stabilization of whole blood samples
The General Hospital Corporation
August 10, 2017 - N°20170223949

Methods for stabilizing blood samples, e. G., clinical blood samples, for storage or transportation before use. Exemplary applications include but are not limited to enrichment of leukocyte subtypes such as t-cells or neutrophils for cytokine and immuno-assays; isolation of progenitor cells from cord blood or peripheral blood for transplantation; isolation of fetal cells from the maternal blood for diagnosis; and ...
Methods and compositions for preparing biological specimens for microscopic analysis
The Board Of Trustees Of The Leland Stanford Junior University
August 03, 2017 - N°20170219465

Methods and compositions are provided for preparing a biological specimen for microscopic analysis. These methods find many uses, for example in medicine and research, e. G., to diagnose or monitor disease or graft transplantation, to study healthy or diseased tissue, to screen candidate agents for toxicity and efficacy in disease modification. Also provided are reagents, devices, kits and systems thereof ...
Platform independent haplotype identification and use in ultrasensitive dna detection
Kennedy Krieger Institute, Inc.
August 03, 2017 - N°20170218447

The present invention provides methods for analyzing blocks of closely spaced snps, or haplotypes for use in identification of the origin of dna in a sample. The methods comprise aligning common alleles of a gene of interest and identifying a region containing a plurality of snps which is flanked by non-polymorphic dna which can be used for primer placement. Any ...
Conditional cytotoxic gene therapy vector for selectable stem cell modification for anti hiv gene therapy
Texas Tech University System
August 03, 2017 - N°20170218397

A method, system, and apparatus for treating a patient with hiv. A vector can be modified from a thymidine kinase gene. The modified vector is expressed in the presence of tat rna. The modified vector is then package and delivered to hiv-infected cells. The replication of hiv is inhibited by eliminating infected cells in the presence of ganciclovir. Modified cells ...
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