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Transcription-related patent applications - as published by the U.S. Patent and Trademark Office (USPTO).


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Method of identifying cosmetic agents for moisturizing skin
The Procter & Gamble Company
November 09, 2017 - N°20170322200

Methods of identifying potential skin moisturizing actives for the treatment of dry skin and method of formulating a moisturizing skin care composition using actives identified by the method. Moisturizing agents can be identified by comparing the transcriptional profile of a skin tissue sample contacted by a test agent to a negative or positive control to determine if the regulation of ...
Methods and reagents for reverse-transcription polymerase chain reaction
Ge Healthcare Uk Limited
November 09, 2017 - N°20170321250

The present invention provides a method of amplifying an rna molecule in a biological sample by reverse transcription pcr (rt-pcr), wherein the rt-pcr is carried out in a solution comprising a polar aprotic solvent; a serum albumin, and a polyol.
Cell-free protein expression using rolling circle amplification product
General Electric Company
November 09, 2017 - N°20170321239

Methods for in vitro transcription and translation from an rca product are provided. The methods comprise providing a double-stranded rca product, wherein the double-stranded rca product consists essentially of tandem repeats of a minimalistic expression sequence. The methods further comprise expressing a protein from the double-stranded rca product in a cell-free expression system.
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Dead guides for crispr transcription factors
Massachusetts Institute Of Technology
November 09, 2017 - N°20170321214

The invention provides for systems, methods, and compositions for altering expression of target gene sequences and related gene products. Provided are structural information on the cas protein of the crispr-cas system, use of this information in generating modified components of the crispr complex, vectors and vector systems which encode one or more components or modified components of a crispr complex, ...
Polymerases
Illumina, Inc.
November 09, 2017 - N°20170321195

Presented herein are methods and compositions for thermostable dna polymerases that may be used to improve the pcr process and to improve the results obtained when using a thermostable dna polymerase in other recombinant techniques such as dna sequencing, nick-translation, and reverse transcription.
Offline voicemail
Illumina, Inc.
November 02, 2017 - N°20170318144

A method for accessing offline voicemail messages within a mobile messaging application may be provided. First, a voice mail message may be received and the voicemail message may be transcribed to text. Next, the voicemail message and the text transcription may be stored. The recipient may then be presented with a list of voicemail messages and the voicemail message may ...
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Oligonucleotide sequence for use in pathway engineering
Illumina, Inc.
November 02, 2017 - N°20170314029

The present invention comprises a novel artificial oligonucleotide sequence which can initiate the transcription of a gene under various conditions at a high level. Further the invention relates to a recombinant dna fragment comprising the artificial oligonucleotide sequence, an expression plasmid comprising the recombinant dna fragment and a host cell transformed with the recombinant dna fragment.
Endogenous retrovirus transcription as a marker for primate naive pluripotent stem cells
Illumina, Inc.
November 02, 2017 - N°20170313978

One or more type 7 long terminal repeat (ltr7) nucleic acid sequences of type h human endogenous retroviruses (hervh) (“ltr7/hervh nucleic acid sequences”) can be used for identifying primate naïve pluripotent stem cells. Ltr7/hervh-associated transcription can be used as a marker for primate naive pluripotent stem cells. A reporter construct that includes ltr7/...
Methods and compositions for in vivo induction of pancreatic beta cell formation
Illumina, Inc.
November 02, 2017 - N°20170312318

Embodiments of the invention stimulate three levels of beta cell physiology: (i) glucose metabolism, (ii) membrane receptor function, and (iii) transcriptional factors that result in the in vivo formation of beta cells in the pancreas for the purpose of treating diabetes. In certain aspects, the methods include the integration of three levels of cellular physiology: metabolism, membrane receptor function, and ...
Method to synthesize personalized phonetic transcription
Adobe Systems Incorporated
October 26, 2017 - N°20170309272

Technology related to improving synthesis of foreign regional nouns using personalized and culturally correct phonetic transcription is described. The technology includes systems and methods for generating personalized speech by receiving an input, the input including textual data, identifying a regional noun in the textual data, and determining a user accent classification based on a context of the input. The method ...
Markers of poor prognosis acute myeloid leukemias (amls) and uses thereof
Rsem, Limited Partnership
October 26, 2017 - N°20170307619

Genes exhibiting specific mutational and/or transcriptional patterns in poor prognosis amls, such as evi1-rearranged acute myeloid leukemias (evi1-r amls), relative to other types of amls and/or normal cd34+ cells, are disclosed. The use of these mutational and/or transcriptional patterns, for example the expression level of the prkc apoptosis wt1 regulator (pawr) gene, for the diagnosis ...
Compositions and related methods for modulating alkaloid production by controlling pmt promoter activation mediated by ...
University Of Virginia Patent Foundation
October 26, 2017 - N°20170306342

Compositions and methods for modifying the production levels of alkaloids in plants are provided. Alkaloid production can be genetically controlled by modulating the transcriptional activation of pmt genes mediated by members of the erf family and/or myc family of transcription factors. Novel nucleotide sequences encoding the myc family of transciption factors are also provided.
Compositions and related methods for modulating transcriptional activation by incorporating gag motifs upstream of core ...
University Of Virginia Patent Foundation
October 26, 2017 - N°20170306341

Compositions and methods for genetically modifying the production levels of nicotine and other alkaloids in plants are provided.
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  • 362+ full patent PDF documents of Transcription-related inventions.
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Ca125 gene and its use for diagnostic and therapeutic interventions
Zumator Biologics, Inc.
October 26, 2017 - N°20170305980

The ca125 gene has been cloned and multiple repeat sequences as well as the carboxy terminus have been identified. The ca125 molecule comprises three major domains: an extracellular amino terminal domain (domain 1); a large multiple repeat domain (domain 2); and a carboxy terminal domain (domain 3) which includes a transmembrane anchor with a short cytoplasmic domain. The amino terminal domain is dominated ...
Treatment of cardiovascular disease using actrii ligand traps
Washington University
October 26, 2017 - N°20170304397

Provided herein are methods of treating diseases associated with vascular calcification and/or cardiovascular disease in a subject by using the level of a biomarker, in particular, snail homolog 1 (snai1), phosphosmad2, phosphosmad3, urinary protein, dickkopf homolog 1 (dkk1), collagen type 1 alpha 1 (col1a1), activin (e. G., free activin), runt-related transcription factor 2 (runx2), alkaline phosphatase (alp), bone-specific alkaline phosphatase (bsap), c-terminal type 1 ...
Re-recognizing speech with external data sources
Washington University
October 19, 2017 - N°20170301352

Methods, including computer programs encoded on a computer storage medium, for improving speech recognition based on external data sources. In one aspect, a method includes obtaining an initial candidate transcription of an utterance using an automated speech recognizer and identifying, based on a language model that is not used by the automated speech recognizer in generating the initial candidate transcription, ...
Apparatus and method for printing steganography to assist visually impaired
Washington University
October 19, 2017 - N°20170300474

An apparatus and method for printing steganography is disclosed. The apparatus comprises a wearable unit and a controlling unit that are programmatically controlled by a processor. The controlling unit converts content to be published into a phoneme transcription for a target language, processes the content and further arranges the processed content as per a specified page layout. Further, the phoneme ...
Thermal bioswitches and related genetic circuits, vectors, cells, compositions, methods and systems
Washington University
October 19, 2017 - N°20170298425

Temperature sensitive transcriptional bioswitches and related genetic circuits and in particular bandpass and/or multiplex genetic circuits, vectors, cells, compositions methods and systems are described.
Conditional rescue system, cells, and methods
Washington University
October 19, 2017 - N°20170298391

A conditional rescue system generally includes a gene transfer system, a polynucleotide including a nuclease-resistant target coding region, and a coding region encoding a conditionally-lethal polypeptide. The gene transfer system is effective to integrate into host cell dna. The polynucleotide including the nuclease-resistant target coding region is under transcriptional control of an inducible promoter. The coding region encoding a conditionally-lethal ...
Control of cellulose biosynthesis by overexpression of a transcription factor
Washington University
October 19, 2017 - N°20170298375

The invention relates to nucleic acids, proteins and methods for modulating the cellulose content of plants.
Plant promoter and 3'utr for transgene expression
Washington University
October 19, 2017 - N°20170298373

This disclosure concerns compositions and methods for promoting transcription of a nucleotide sequence in a plant or plant cell, employing a zea mays grmzm2g138258 promoter. Some embodiments relate to a zea mays grmzm2g138258 promoter that functions in plants to promote transcription of operably linked nucleotide sequences. Other embodiments relate to a zea mays grmzm2g138258 3′utr that ...
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