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Transcription-related patent applications - as published by the U.S. Patent and Trademark Office (USPTO).


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System for real time dialing analysis
Tcn Incorporated
June 14, 2018 - N°20180167505

A system and method for providing quality calls and predictive and real-time dialing analysis. The system may provide easy calling for an agent and simple feedback for a client.
Providing targeted content
Meadcon Llc
June 14, 2018 - N°20180165770

An apparatus for providing targeted content to a reference subscribing account includes a processor, having a transcription module to transcribe subscriber content uploaded from the subscribing account, a scoring module to assign an accuracy score to the transcribed subscriber content for accuracy based on predetermined accuracy metrics, and store, to a learning database, the transcribed subscriber content when the assigned ...
Modified cyanobacteria
Saitama University
June 14, 2018 - N°20180163237

Provided is a cyanobacterium improved in fatty acid productivity. A method for producing a modified cyanobacterium, comprising causing loss of function of a lexa transcriptional regulator and acyl-acp synthetase in a cyanobacterium..
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Engineering of a minimal sacas9 crispr/cas system for gene editing and transcriptional regulation optimized ...
Tsinghua University
June 14, 2018 - N°20180163188

The presently claimed invention offers programmable and precise regulation of cas9 functions by utilizing a set of compact cas9 derivatives created by deleting conserved hnh and/or rec-c domains based on the structural information across variant class 2 crispr effectors. In addition, a novel strategy for engineering the dimeric grna-guided nuclease by splitting the mini-dsacas9 and fusing the foki domain right ...
System and methods for detecting ribosome inhibition
Stc.unm
June 07, 2018 - N°20180156783

This disclosure describes a cell genetically modified to detect ribosome inhibition in the cell and methods involving such a cell. Generally, the genetically-modified cell includes an aminoglycoside-sensitive orthogonal 16s rrna (o-16s) coding region bearing a mutated anti-shine-dalgarno (o-asd) sequence, a repressor/operator system, and a polynucleotide encoding a detectable reporter under transcriptional control of the repressor/operator system.
Identification of transcription factors that improve nitrogen and sulphur use efficiency in plants
Instituto Nacional De Investigacion Y Tecnologia Agraria Y Alimentaria
June 07, 2018 - N°20180155735

The present invention provides an expression cassette comprising at least one polynucleotide comprising a nucleotide sequence selected from the group consisting of: a) a nucleotide sequence that encodes a polypeptide having the amino acid sequence set forth in seq id nos. 13-24; and b) a nucleic acid sequence that encodes a polypeptide having the amino acid sequence sharing at least 50%, ...
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Compositions and methods for identifying polynucleotides of interest
The Regents Of The University Of California
June 07, 2018 - N°20180155712

Provided are constructs and methods useful for the screening and identification of polynucleotide sequences of interest, in particular promoters, rna stability modifying sequences and transcriptional modifying sequences.. .
Substituted heterocyclyl derivatives as cdk inhibitors
Aurigene Discovery Technologies Limited
June 07, 2018 - N°20180155293

The present invention provides substituted heterocyclyl derivatives of formula (i), which are therapeutically useful, particularly as selective transcriptional cdk inhibitors including cdk7, cdk9, cdk12, cdk13 and cdk18, more particularly transcriptional cdk7 inhibitors. These compounds are useful in the treatment and prevention of diseases and/or disorders associated with selective transcriptional cdks in a mammal.
Generating structured text content using speech recognition models
Google Inc.
May 31, 2018 - N°20180150605

Methods, systems, and apparatus, including computer programs encoded on computer storage media for speech recognition. One method includes obtaining an input acoustic sequence, the input acoustic sequence representing one or more utterances; processing the input acoustic sequence using a speech recognition model to generate a transcription of the input acoustic sequence, wherein the speech recognition model comprises a domain-specific language ...
Diagnosis and treatment of mers-related renal disease
Emv Mers Limited
May 31, 2018 - N°20180149659

Methods for treating, diagnosing, and providing prognostic information for kidney disease related to mers-cov infection are described. Transcription and translation products (for example, mrna or peptides) of fgf2, smad7, and/or sequences upstream of fgf2 are useful as markers that indicate kidney disease and/or provide prognostic information related to the course of kidney disease related to mers-cov infection.
Compositions and methods for modifying genomes
Benson Hill Biosystems, Inc.
May 31, 2018 - N°20180148735

Compositions and methods for modifying genomic dna sequences are provided. The methods produce double-stranded breaks (dsbs) at pre-determined target sites in a genomic dna sequence, resulting in mutation, insertion, and/or deletion of dna sequences at the target site(s) in a genome.
Use of andrographolide derivatives in preparation of medicaments for preventing and treating inflammatory bowel diseases
Guangzhou Magpie Pharmaceuticals Co., Ltd.
May 31, 2018 - N°20180147181

The present invention provides uses of an andrographolide derivative in preparation of a medicament for preventing and treating inflammatory bowel disease. The andrographolide derivative al-1 has the mechanisms, for the treatment of ulcerative colitis, of scavenging of free radicals, inhibition of nf-κb signaling pathway activation and cox-2 expression, activation of ppar-γ expression, and thus can ...
Multi-use scope
The Regents Of The University Of Colorado, A Body Corporate
May 31, 2018 - N°20180146839

An endoscope/triplescope (combined gastroscope, bronchoscope, laryngoscope) device and/or system includes an endoscope having an outer diameter of less than about 4.0 millimeters, in particular less than about 3.5 millimeters, that allows high resolution viewing having a distal element including an optical element that allows four way tip deflection. Further, the device may include a scope stiffening apparatus to minimize the ...
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  • 362+ full patent PDF documents of Transcription-related inventions.
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Contextual dictionary for transcription
Microsoft Technology Licensing, Llc
May 24, 2018 - N°20180143970

The functionality of devices used to transcribe events is augmented with a contextual dictionary for the event to be transcribed. Contextual information for the event are discovered, which are used to customize the dictionary to the event and to locate supplemental contextual information in a graph database to further customize the event.
Methods and compositions for detecting zika virus in semen
Genetics & Ivf Institute
May 24, 2018 - N°20180142310

Provided herein is a highly sensitive and robust method for zika detection in semen, as well as related compositions. The method can include: (a) extracting nucleic acids from a human semen sample; (b) detecting zika virus nonstructural protein 5 (ns5) mrna using real-time reverse-transcription polymerase chain reaction (rrt-pcr); and (c) simultaneously, in the rrt-pcr, detecting human beta-actin mrna as positive control..
Blocking oligonucleotides
May 24, 2018 - N°20180142290

A blocking oligonucleotide (10, 10a, 10a′, 10a″, 10b, 10c, 10d, 10e) comprises a 3′-end complementary sequence (13) complementary to a 3′-end sequence (23) of a globin mrna molecule (20; 20a, 20b) and a poly-a complementary sequence (12) of at least one nucleotide complementary to at least a portion of a poly-a sequence (22) of the globin mrna molecule (20, 20a, 20b). The blocking ...
Replication-deficient rna viruses as vaccines
Max-plank Gesellschaft Zur Forderung Der Wissenschaften E.v.
May 24, 2018 - N°20180142256

The present invention relates to a genome-replication-deficient and transcription-competent negative-strand rna virus, which can be used for the expression of transgenes and in particular for the area of vaccine development.. .
Cis/trans riboregulators
Trustees Of Boston University
May 24, 2018 - N°20180142247

The present invention provides nucleic acid molecules, dna constructs, plasmids, and methods for post-transcriptional regulation of gene expression using rna molecules to both repress and activate translation of an open reading frame. Repression of gene expression is achieved through the presence of a regulatory nucleic acid element (the cis-repressive rna or crrna) within the 5′ untranslated region (5′ utr) of ...
Artificial transcription factors and uses thereof
Wisconsin Alumni Research Foundation
May 24, 2018 - N°20180142215

The present invention relates to artificial transcription factors (atfs) that alter gene expression, including inducing pluripotency in cells or promoting the conversion of cells to specific cell fates. In particular, provided herein is a zinc-finger based atf library that can be screened in cells by looking for expression of a specific gene (e.g., reporter expression), monitoring for cell surface ...
Targeted nanocarriers for targeted drug delivery of gene therapeutics
Rodos Biotarget Gmbh
May 24, 2018 - N°20180140717

A targeted nanocarriers also termed nanomedicines and methods of preferentially, or actively, targeting and delivering a tool for gene transfer or genome editing (i.e., a plasmid or a restriction enzyme such as a zinc finger nuclease, a crispr/cas system, or a talen) or a tool for gene silencing or post-transcriptional regulation of gene expression (i.e., a microrna, ...
Multi-microphone speech recognition systems and related techniques
Apple Inc.
May 17, 2018 - N°20180137864

A speech recognition system for resolving impaired utterances can have a speech recognition engine configured to receive a plurality of representations of an utterance and concurrently to determine a plurality of highest-likelihood transcription candidates corresponding to each respective representation of the utterance. The recognition system can also have a selector configured to determine a most-likely accurate transcription from among the ...
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