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Date/App# patent app List of recent Topical-related patents
04/10/14
20140101267
 Selecting user accounts in social network to answer question patent thumbnailSelecting user accounts in social network to answer question
Messages generated by user accounts in a social networking application over a period of time are processed to determine the subjects and topic associated with the messages, as well as the geographical locations of the users associated with the user accounts, and the times when the users associated with the accounts are most active. The determined, subject, time, and location information is used to create a model that may be used to predict whether a user in the social networking application is willing, available, and has the knowledge or topical affinity to answer a question proposed by another user in the social networking application based on a subject, time, and/or location associated with the question.
04/10/14
20140100589
 Personal care cleaning article patent thumbnailPersonal care cleaning article
The present invention provides personal cleaning articles useful for cleaning and/or exfoliating the skin. These articles provide multiple distinct patterns of relatively smooth and coarse elements to provide a user the ability to readily achieve the desired degree of cleansing and/or exfoliation.
04/10/14
20140100436
 Electrode sensor kit, electrode assembly, and topical preparation for establishing electrical contact with skin, use thereof, and method of electro-impedance tomography (eit) imaging using these patent thumbnailElectrode sensor kit, electrode assembly, and topical preparation for establishing electrical contact with skin, use thereof, and method of electro-impedance tomography (eit) imaging using these
An electrode sensor kit for establishing electrical contact with skin comprises at least one contact element and a preparation comprising a mixture of water and at least one lipid for enhancing electrical contact properties between said contact element and the skin, wherein said mixture forms an emulsion, in particular a water-in-oil or an oil-in-water emulsion, having a conductivity of less than 3 ms/cm. An electrode assembly for electrical impedance tomography which comprises said kit is characterized in that (a) said at least one contact element forms an electrode or sensor plate, and (b) said at least one contact element comprises a layer of said preparation..
04/10/14
20140100288
 Foaming topical antimicrobial cleaning compositions patent thumbnailFoaming topical antimicrobial cleaning compositions
Provided are largely aqueous topical antimicrobial cleaning composition which provides an antimicrobial benefit, as well as methods for their production and methods for their use. The compositions comprise at least two different cationic surfactants which provide a primary antimicrobial benefit, and as a predominant further surfactant an amine oxide surfactant.
04/10/14
20140100232
 Combination treatment for rosacea patent thumbnailCombination treatment for rosacea
The invention relates to a method of treating erythema and/or telangiectasia associated with rosacea in a patient in need thereof by topically administering an effective amount of a combination of brimonidine or a pharmaceutically acceptable salt thereof and oxymetazoline or a pharmaceutically acceptable salt thereof to the site of erythema and/or telangiectasia on the skin of the patient. The invention further relates to topical compositions including the combination of compounds and a pharmaceutically acceptable carrier..
04/10/14
20140100181
 Topical pharmaceutical composition containing a water-sensitive active principle patent thumbnailTopical pharmaceutical composition containing a water-sensitive active principle
A topical pharmaceutical composition including, as a pharmaceutical active agent, a water-sensitive compound in a solubilised form in a physiologically acceptable medium is described. A method for preparing such a composition, and uses thereof in dermatology are also described..
04/10/14
20140100180
 Topical pharmaceutical composition based on semifluorinated alkanes patent thumbnailTopical pharmaceutical composition based on semifluorinated alkanes
The invention provides liquid or semi-solid pharmaceutical compositions for topical administration comprising a semifluorinated alkane. The compositions are useful for the delivery of active ingredients into the deep layers of the skin or skin appendages.
04/10/14
20140099389
 Topical anti-inflammatory combination patent thumbnailTopical anti-inflammatory combination
Provided, among other things, is a method of treating or ameliorating an indication of non-mucosal topical tissue comprising periodically applying to such disease affected tissue a composition comprising: an effective amount of an appropriate composition of herbal bioactive comprising active(s) of one or more of sambucus nigra, centella asiatica or echinacea purpurea, and an effective amount of a quaternary ammonium surfactant.. .
04/10/14
20140099383
 Topical dermal formulations patent thumbnailTopical dermal formulations
An autologous topical formulation containing conditioned medium obtained from culture of autologous fibroblasts has been developed. Unlike other topical formulations, it is autologous since it is derived solely from cells obtained by the person who is to use the formulation.
04/10/14
20140099355
 Method and composition for the treatment of moderate to severe keratoconjunctivitis sicca patent thumbnailMethod and composition for the treatment of moderate to severe keratoconjunctivitis sicca
The present invention relates to topical ophthalmic compositions for treating or preventing epithelial lesions or ophthalmic disorders, including dry eye or keratoconjunctivitis sicca.. .
04/10/14
20140099296
Topically or orally applied aloe, distilled water, sodium chloride, and lysozyme mixture and method of producing the mixture
A skin and/or oral treatment mixture for treating tattooed or pierced skin such as that resulting from a body piercing, oral piercing, or tattoo procedure includes non-iodized sodium chloride, distilled water, aloe, and lysozyme. The distilled water is preferably a product of vapor or steam distillation.
04/10/14
20140099273
Topical skin care formulations comprising plant extracts
Disclosed is a topical skin composition and corresponding methods for its use that includes an extract from bauhinia glauca, an extract from rhodendron siderophyllum, and an extract from circidiphyllum japonicum.. .
04/10/14
20140099268
Cosmetic and pharmaceutical compositions and methods using 2-decarboxy-2-phosphinico derivatives
A method for treating hair loss in mammals uses compositions containing 2-decarboxy-2-phosphinico prostaglandin derivatives. The compositions can be applied topically to the skin.
04/10/14
20140099262
Isotopically labeled cdp-choline and uses thereof
The present invention provides cdp-choline (citicoline) and any salt thereof comprising at least one isotopically labeled carbon atom directly bonded to at least one deuterium atom, a composition comprising said cdp-choline, uses thereof, methods for diagnosing and evaluating a state, condition, or disease in a subject utilizing cdp-choline of the invention and kits comprising cdp-choline of the invention.. .
04/03/14
20140094847
Fluid applicator
Fluid applicators utilizing a cutter and an ampule containing fluids, such as topical adhesives, and methods for safe, sterile, one-time use of fluid applicators for expressing fluids, such as wound sealing adhesives, are provided.. .
04/03/14
20140094515
Cosmetic particles that transform from hard to soft particles comprising hydrogenated long-chain triglyceride oils
Cosmetic particle compositions are provided which are adapted to form hard cosmetic particles that transform to soft cosmetic particles after their incorporation into topical formulations, particularly surfactant-based topical formulations. The composition includes one or more partially or fully hydrogenated triglyceride oils, at least 50% of which have at least 15% by weight fatty acid moieties with carbon chain lengths of c18 or higher.
04/03/14
20140094470
Combination treatment for dermatological conditions
The invention relates to a method of treating dermatological conditions or symptoms associated therewith in a patient in need thereof by topically administering an effective amount of a combination of brimonidine or a pharmaceutically acceptable salt thereof and oxymetazoline or a pharmaceutically acceptable salt thereof to the affected area of skin on the patient. The invention further relates to topical compositions including the combination of compounds and a pharmaceutically acceptable carrier..
04/03/14
20140094469
Methods and compositions for safe and effective treatment of erythema
Improved methods and compositions for safe and effective treatment of erythema or a symptom associated with erythema in a subject are described. The methods involve topically applying to an affected skin area a topical composition comprising about 0.3% to about 10% by weight of brimonidine and a pharmaceutically acceptable carrier..
04/03/14
20140093583
Povidone-iodine topical composition
The present invention relates to a topical pharmaceutical composition comprising povidone-iodine, a tertiary amide, surfactant and coconut oil, useful for killing microbes and treating wounds or sores on the surface of the skin.. .
04/03/14
20140091006
Single finger and dual finger medication delivery devices, systems and kits; and methods of using the same
Embodiments described herein generally relate to improved devices, systems, kits, products and methods related to topical medicament application of measured dosages. The kits and devices can single use and/or disposable for example..
04/03/14
20140090598
Isotopically-enriched boron-containing compounds, and methods of making and using same
An isotopically-enriched, boron-containing compound comprising two or more boron atoms and at least one fluorine atom, wherein at least one of the boron atoms contains a desired isotope of boron in a concentration or ratio greater than a natural abundance concentration or ratio thereof. The compound may have a chemical formula of b2f4.
03/27/14
20140090098
Methods and compositions for extending shelf life of plant products
The invention provides compositions and methods related to selective inhibition of ppo11 and use for improving shelf life of a plant or parts thereof. In accordance with the invention, for example, compositions for topical application to a plant or part thereof, are provided that can reduce browning of the plant or part thereof to extend shelf life..
03/27/14
20140089439
Context sensitive user group communications
A system and method for resolving topically relevant contacts for a user is provided. One example embodiment provides for a method including acts of presenting, within a web page, a communication list with content that is presented to various user based at least in part on the users being associated with another user and the topical content of the web page.
03/27/14
20140089090
Searching data storage systems and devices by theme
The invention teaches systems, methods and devices for searching data storage systems and devices by a topical category known as a theme. It is emphasized that this abstract is provided to comply with the rules requiring an abstract that will allow a searcher or other reader to quickly ascertain the subject matter of the technical disclosure.
03/27/14
20140088528
Apparatus for topical negative pressure therapy
Apparatus and a method for the provision of topical negative pressure therapy to a wound site are described, the apparatus comprising: vacuum generating means for generating a negative pressure at said wound site said vacuum generating means being operably connected to a dressing at said wound site by aspiration conduit means; pressure sensing conduit means in fluid communication with said aspiration conduit means at a junction adjacent said dressing; first pressure sensing means between said junction and said vacuum generating means; second pressure sensing means operably associated with said pressure sensing conduit means; diagnostic means in communication with said first and second pressure sensing means; and control means in communication with said diagnostic means for controlling pressure in said aspiration and said pressure sensing conduit means.. .
03/27/14
20140088478
Topical proprioceptive acl tube and methods of use
A topical proprioceptive tube and method of use for enhancing performance, reducing the risk of knee injury, or both. The tube includes a flexible sleeve having at least: a hamstring buttress, a knee buttress, or both, wherein the hamstring buttress and the knee buttress are configured to be coupled to the interior of the flexible sleeve such that the hamstring buttress applies pressure to at least a portion of one of the subject's hamstring muscles and the knee buttress applies pressure to at least a portion of the subject's vastus medialis obliquus (vmo) when worn by the subject to provide the desired effect..
03/27/14
20140088475
Proprioceptive topical leg gear and methods of use
A topical leg gear for enhancing performance and reducing the risk of injury. The topical leg gear and kits preferably comprise a flexible sleeve and a lateral foot-ankle buttress, malleolus bone buttresses, and a peroneal longus buttress.
03/27/14
20140088384
Intra-operative molecular imaging
A system for detecting tumor margins includes a topical protease-specific, fluorescence imaging probe that is activatable by enzymatic activation to produce a visually differentiated signal upon topical application to a targeted cancer cell that secretes an enzyme that activates the protease-specific, fluorescence imaging probe, means for topically administering the imaging probe to the cancer cell; and an imaging device to detect activation of the imaging probe administered to the cancer cell.. .
03/27/14
20140088199
Ophthalmic treatments
Aqueous compositions suitable for topical administration to the human or animal eye contain at least one water-soluble polymeric ophthalmic lubricant, such as hyaluronate, carbomer gel or hypromellose, together with a water-soluble analgesic. The analgesic may be an opiod, particularly an opioid having an affinity for 5-ht receptors, such as tramadol.
03/27/14
20140088195
Topical ketoprofen composition
A topical composition, specifically an oil-in-water emulsion, comprised of ketoprofen and oxybenzone in a physiologically acceptable topical carrier. The composition is applied topically to alleviate pain, especially pain associated with migraine headache.
03/27/14
20140088134
Pharmaceutical composition for topical application
A pharmaceutical composition comprises a solution having a ph of from 5 to 7.5, including loratadine and/or desloratadine. The composition is suitable for treatment of e.g.
03/27/14
20140088049
Method and apparatus for vitamin d enhancement in mushrooms
An apparatus and method for increasing vitamin d content in mushrooms is disclosed. A mushroom slurry of comminuted or pulverized mushrooms or mushroom parts and liquid, such as water, is passed under a uv light source and subjected to one or more pulses of uv light.
03/27/14
20140087001
Pharmaceutical compositions and topical use thereof
The present invention relates to methods for the preparation of compositions comprising adipose tissue-derived secretions, for example those derived from bovine adipose tissue, and the use of such compositions in the preparation of a pharmaceutical composition for topical use. The invention also relates to the use of adipose tissue-derived secretions and pharmaceutical compositions thereof for the topical treatment of a non-inflammatory condition, for example the treatment of a skin condition, and for the stimulation of hair growth in a subject by topical application.
03/27/14
20140086980
Treatment of erectile dysfunction and other indications
The present invention generally relates to the transdermal delivery of various compounds. In some aspects, transdermal delivery may be facilitated by the use of a hostile biophysical environment.
03/27/14
20140086863
Cosmetic composition
Provided is a method of treating aged skin, comprising topically applying to the aged skin a composition comprising a compound of formula (i) in an amount effective to provide an anti-ageing effect. The compound of formula (i) is used to prevent skin and/or to help to maintain or improve moisture retention and/or to fight against the signs of skin ageing.
03/27/14
20140086834
New i-arylpiperazinic ligands of 5-ht7 receptor and use thereof
The invention relates to a new class of compounds able to inhibit with high affinity and selectivity the 5-ht7 receptor. The invention also relates to the utilization of such compounds as medicaments useful in the treatment and prevention of 5-ht7 receptor relating disorders of the central nervous system.
03/20/14
20140081941
Semantic ranking using a forward index
Methods, computer systems, and computer-readable media for generating semantic ranking features using a forward index are provided. A search query is received and is analyzed for one or more semantic units including semantic patterns, topical categories, and entities.
03/20/14
20140080911
Polymeric adhesive matrix with salified carboxylic groups for transdermal use
Polymeric matrices for the controlled release of medicaments for the topical transdermal use comprising copolymers of acrylic and/or methacrylic acid or esters thereof having a tg lower than 0.degree. C., whose free carboxy groups are salified with compatible organic or inorganic bases.
03/20/14
20140080845
Use of allopurinol for the treatment of hand foot skin reaction
Use of allopurinol or a pharmaceutically acceptable salt thereof for the treatment or prevention of hand foot skin reaction (hfsr) induced by multitargeted kinase inhibitor (mki) therapy. The allopurinol or its salt is administered topically to the affected areas, palms and soles, preferably in the form of a cream..
03/20/14
20140080836
Methods and compositions for treating or preventing erythema
Methods and products for treating or preventing erythema or a symptom associated with erythema in a subject are described. The methods involve topically applying to an affected skin area a topical aqueous gel composition comprising about 0.01% to about 10% by weight of at least one α-adrenergic receptor agonist and a pharmaceutically acceptable carrier..
03/20/14
20140079815
Compositions for stimulating hair growth and preventing hair loss
A composition for promoting hair growth, slowing hair loss, and for preventing or minimizing hair loss that do not suffer from the deficiencies of the prior art. One exemplary embodiment is directed to a topical formulation for hair, the formulation combining arnica and aqua ammonia to promote hair growth and hair loss diminution..
03/20/14
20140079804
Compositions and methods for treatment of infections
This invention relates to the field of topical treatments for infections such as nail infections, particularly fungal infections of the nail commonly referred to as onychomycosis. Particularly, the invention relates to novel compositions containing peroxide for the treatment of such nail infections and other infections..
03/20/14
20140079761
Systems and methods for treatment of acne vulgaris and other conditions with a topical nitric oxide delivery system
The present invention generally relates to compositions and methods for treatment of subjects having or at risk of acne or other conditions. In some cases, the composition may include nitric oxide.
03/20/14
20140079744
Even deposition and low rub-off compositions
Improved deposition and low rub-off compositions are described. The compositions are emulsions with aqueous-based film-forming resins in the water phase and particle with hydrophobic material in the oil phase of the emulsion.
03/20/14
20140079657
Topical compositions and methods of use
Compositions and methods of treatment are disclosed using compositions of extracts from the fruit of the synsepalum dulcificum tree, which when applied topically in mammals, can provide benefit for dermatological and joint conditions. The extracts also contain anti-inflammatory, antimicrobial and spermicidal activity in vitro..
03/20/14
20140079655
Compositions for enhancing nail health
The present invention is directed to compositions and methods for enhancing the health of nails and cuticles in a mammal, including humans. The compositions may be administered topically to the nail bed, nail matrix and cuticle in an amount effective to enhance nail health.
03/13/14
20140074728
System for social care routing, prioritization and agent assistance
A system for social care routing, prioritization and agent assistance for interfacing with a carrier network, a social listening device, a social network or proprietary social feedback apparatus, and a contact center and contact center database. Author postings, demographic information, sentiment, topical relevancy, and customer service requests and other data are used for prioritization, agent assistance and routing.
03/13/14
20140074005
Dressings with a foamed adhesive layer
A dressing suitable for topical application to the body, including a carrier substrate having a first side and opposing second side; and a layer of a foamed adhesive composition applied to the second side of the carrier substrate, where the layer of foamed adhesive composition includes a substantially homogeneous distribution of closed cells having an inert gas contained therein.. .
03/13/14
20140073697
Delivery of ibuprofen and other compounds
The present invention generally relates to the transdermal delivery of various compositions. In some aspects, the transdermal delivery may be facilitated by the use of a hostile biophysical environment.
03/13/14
20140073659
Treatment for vitiligo
Compounds i and ii, as well as prodrugs, hydrates, solvates, n-oxides, salts and pharmaceutical compositions containing them, are useful for treating vitiligo. In certain embodiments, the compounds are provided in topical compositions..
03/13/14
20140073649
Isotopically enriched arylsulfonamide ccr3 antagonists
Provided herein are isotopically enriched arylsulfonamides, for example, of formula i, that are useful for modulating ccr3 activity, and pharmaceutical compositions thereof. Also provided herein are methods of their use for treating, preventing, or ameliorating one or more symptoms of a ccr3-mediated disease, disorder, or condition..
03/13/14
20140073615
Treatment of psoriasis
A lipid layer forming composition for topical treatment of psoriasis comprises volatile silicone oil, polar lipid, c2-c4 aliphatic alcohol, and a pharmacologically effective amount of an agent for the treatment of psoriasis, wherein the silicone oil has a boiling point above 180° c., in particular above 200° c. The composition does not comprise polymer silicone.
03/13/14
20140073613
Topical formulation for treatment of hyperkeratotic skin
The present invention relates in general to topical compositions having improved antimicrobial effect useful for the treatment of hyperkeratotic skin conditions. More specifically, the present invention relates to topical compositions comprising a combination of one or more alfa-hydroxy acids, urea, glycerol, and panthenol, as well as the use of such compositions for the treatment of hyperkeratotic skin conditions, in particular on the feet, and also on other body areas where thick skin is noted and where infections should be avoided..
03/13/14
20140073612
Transdermal delivery system kit
A transdermal delivery kit that enhances the efficacy of a topical drug includes at least one drug dispensing device, a lipophilic base, a hydrophilic base, a lipid-soluble active ingredient, a water-soluble active ingredient, a first container for mixing the lipophilic base with the lipid-soluble active ingredient to form a first compound, a second container for mixing the hydrophilic base with the water-soluble active ingredient to form a second compound, a mixing member, and instructions for compounding the lipophilic base with the lipid-soluble active ingredient to form the first compound, compounding the hydrophilic base with the water-soluble active ingredient to form the second compound, and mixing the first compound and the second compound to form a transdermal pharmaceutical delivery system capable of delivering a drug to the dermal layer of the skin.. .
03/13/14
20140072648
Camel milk-based topical pharmaceutical composition
The present invention relates to a novel pharmaceutical composition with milk of immunized camelid, particularly camelus dromedarius as the main component (i.e. Active ingredient) and a method for the treatment or prevention of skin or mucus membrane infections, particularly acne vulgaris.
03/13/14
20140072618
Topical delivery of l-arginine to cause beneficial effects
A preparation is disclosed for producing enhanced blood flow in tissue thus causing beneficial effects such as promoting hair growth on scalp tissuelacking sufficient hair, restoring normal sexual function in males with erectile dysfunction. Specifically, this is a preparation which provides local delivery of the amino acid l-arginine, an important biological precursor to the main substance which is responsible for relaxation of blood vessels permitting enhancement of blood flow.
03/06/14
20140068521
Information display
A system and method for a computer implemented display of information organizes a visual screen display to a user in such a way that the user is able to efficiently select information content, and then be presented with topical associations relating to that content. The display enables selection of a particular information segment having an association with particular information content.
03/06/14
20140068011
Predicting content performance with interest data
Systems and methods for predicting content performance with interest data include receiving a content selection request that includes a client identifier. One or more topical interest categories associated with the client identifier may be used as inputs to a prediction model to predict the likelihood of an online action occurring as a result of third-party content being selected.
03/06/14
20140067844
System and method for context enhanced mapping
A system and method for context enhanced mapping. A request is received from a user over a network for a map comprising an identification of a physical location, and at least one criteria.
03/06/14
20140066843
Microneedle devices and methods
A medical device, comprising: an array of microneedles, and a coating disposed on the microneedles, wherein the coating comprises: a local anesthetic selected from the group consisting of lidocaine, prilocaine, and a combination thereof; and a local anesthetic dose-extending component selected from the group consisting of tetracaine, ropivacaine, bupivacaine, procaine and a combination thereof; wherein the local anesthetic is present in an amount of at least 1 wt-% based upon total weight of solids in the coating, and wherein the local anesthetic and dose-extending component are in a non-eutectic weight ratio; a medical device, comprising an array of dissolvable microneedles, the microneedles comprising: a dissolvable matrix material; at least 1 wt-% of a local anesthetic selected from the group consisting of lidocaine, prilocaine, and a combination thereof; and a local anesthetic dose-extending component selected from the group consisting of tetracaine, ropivacaine, bupivacaine, procaine and a combination thereof; wherein the local anesthetic and dose-extending component are in a non-eutectic weight ratio, and wherein wt-% is based upon total weight of solids in all portions of the dissolvable microneedles which contain the local anesthetic; a method of extending a topically delivered local anesthetic dose in mammalian tissue using the devices; and methods of making the devices are provided.. .
03/06/14
20140066842
Microneedle devices and methods
A medical device, comprising: an array of microneedles, and a coating disposed on the microneedles, wherein the coating comprises: a local anesthetic selected from the group consisting of lidocaine, prilocalne, and a combination thereof; and a local anesthetic dose-extending component selected from the group consisting of alpha 1 adrenergic agonists, alpha 2 adrenergic agonists, and a combination thereof; wherein the local anesthetic is present in an amount of at least 1 wt-% based upon total weight of solids in the coating, and wherein the dose-extending component/local anesthetic weight ratio is at least 0.0001; a medical device, comprising an array of dissolvable microneedles, the microneedles comprising: a dissolvable matrix material; at least 1 wt-% of a local anesthetic selected from the group consisting of lidocaine, prilocalne, and a combination thereof; and a local anesthetic dose-extending component selected from the group consisting of alpha 1 adrenergic agonists, alpha 2 adrenergic agonists, and a combination thereof; wherein the dose-extending component/local anesthetic weight ratio is at least 0.0001, and wherein wt-% is based upon total weight of solids in all portions of the dissolvable microneedles which contain the local anesthetic; a method of extending a topically delivered local anesthetic dose in mammalian tissue using the devices; and methods of making the devices are provided.. .
03/06/14
20140066837
Skin care compositions and methods
A skin care composition can include a growth factor, such as an epidermal and/or keratinocyte growth factor (egf, kgf), a dna repair enzyme encapsulated by a liposome, and a carrier suitable for topical administration of the egf and/or kgf and dna repair enzyme to a subject's skin. One, two, or more modalities, such as sonophoresis, can be used to synergistically increase transdermal penetration of compositions.
03/06/14
20140066511
Topical delivery of l-arginine to cause beneficial effects
A preparation is disclosed for producing enhanced blood flow in tissue thus causing beneficial effects such as promoting hair growth on scalp tissue lacking sufficient hair, restoring normal sexual function in males with erectile dysfunction. Specifically, this is a preparation which provides local delivery of the amino acid l-arginine, an important biological precursor to the main substance which is responsible for relaxation of blood vessels permitting enhancement of blood flow.
03/06/14
20140066493
Compositions and methods for treatment of ear disorders
The present invention relates to pharmaceutical compositions useful for topical, non-invasive delivery of an oligonucleotide to the ear and to methods for the treatment of an ear disorder, including hearing loss arising from chemical-induced ototoxicity, acoustic trauma and presbycusis; and microbial infections. The method comprises topically administering to the ear of a subject in need thereof a pharmaceutical composition comprising an inhibitory oligonucleotide, a permeability enhancer and a pharmaceutically acceptable carrier, wherein the oligonucleotide reduces or inhibits expression of a gene associated with the ear disorder in the subject..
03/06/14
20140066481
Water-free pharmaceutical compositions suitable for local anaesthetics
The present invention relates to a water-free pharmaceutical composition comprising one or more local anaesthetics in base form and which is suitable for topical administration. The composition further comprises a lipid vehicle comprising long-chain triglycerides (lct) and at least 10% by weight of medium-chain monoglycerides (mcm) selected so the composition has an at least semi-solid appearance at the body temperature at the site of administration.
03/06/14
20140066399
Pharmacological preparation for topical use containing npalmitoyl-vanillamide
The present invention relates to topical preparations containing n-palmitoyl-vanillamide having hyperalgesic activity. In particular, the invention relates to n-palmitoyl-vanillamide for use in the treatment of pathologies selected from: post-herpetic neuralgia, neuralgia of trigeminus, occipital neuralgia, dental neuralgia, glottopharyngeal neuralgia, uremic neuralgia, diabetic neuralgia, headache of different origin, neuropathic itch, neurogenic itch, uremic itch, vulvodinia, vulvar vestibulitis, ano-rectal pain and itch, balano-preputial pain and itch, painful urogenital disorders of dogs and cats, psoriasis-associated pruritus and pain, itching skin diseases (e.g.
03/06/14
20140065625
Isotopically-labeled proteome standards
The invention provides methods for quantifying biomolecules, such as polypeptides in mass spectrometric analysis. The methods include use of a biomolecule standard having at least one atomic isotope different than that of the naturally occurring isotopes in the biomolecule of interest.
03/06/14
20140065209
Probiotic bacteria for the topical treatment of skin disorders
The present invention relates to a probiotic bacteria, and/or soluble metabolite of a probiotic bacteria and/or a cell lysate of a probiotic bacteria for use in the treatment of a disorder associated with tight junction function, characterised in that the probiotic bacteria, soluble metabolite of a probiotic bacteria and/or a cell lysate of a probiotic bacteria is formulated for topical administration.. .
03/06/14
20140065196
Cosmetic skin care compositions
The invention relates to a composition formulated for topical application for the prevention, mitigation or abrogation of skin aging or skin imperfections in a subject. The composition comprises an insoluble copper oxide as a primary active ingredient therein, wherein said insoluble copper oxide is present at a concentration of between about 0.15%-about 0.75% w/w, the insoluble copper oxide is present as particles ranging in a size of from between about 0.5 to about 10 microns or a combination thereof..
03/06/14
20140065191
Topical pharmaceutical composition comprising nanonized silver sulfadiazine
The invention relates to a topical pharmaceutical composition for burn treatment and microbial infections on human beings or animals. The pharmaceutical composition comprises 0.1% w/w to 1.0% w/w of an antimicrobial drug, i.e., silver sulfadiazine and 0.2% w/w antiseptic, i.e., chlorhexidine gluconate, wherein silver sulfadiazine is in nanonized form..
03/06/14
20140065086
Dickkopf-1 expression modulating compositions and uses thereof
The present invention relates generally to compositions for topical application to the skin which comprise at least one dickkopf-1 expression modulator and the use of such compositions to provide benefits to the skin, including but not limited to lightening or darkening skin; treating hyper or hypopigmented skin; increasing or decreasing skin thickness; reducing or increasing skin hirsuteness; and/or changing skin phenotype from non-palmoplantar to palmoplantar.. .
03/06/14
20140065085
Topical skin care formulations
A white, color-stable, stain-free emulsion formulation containing vanillin for sunless tanning. The amount of vanillin can be adjusted, from about 1% up to about 45%, to provide light or dark tanning of the skin.
03/06/14
20140065083
Topical skin care formulations comprising plant extracts
Disclosed are topical skin compositions and corresponding methods of their use that include an extract from artabotrys hexapetalus, an extract from sassafras tzumu, and an extract from prunus salicina.. .
03/06/14
20140065082
Topical skin care formulations
A white, color-stable anti-aging emulsion formula containing coq10 and/or vanillin. The amount of vanillin can be adjusted to provide light or dark tanning of the skin.


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Topical topics: Amino Acid, Emulsifiers, Homogeneous, Crystallin, Prophylaxis, Peripheral Vascular Disease, Vascular Disease, Circulation, Antimicrobial, Nitric Oxide, Spectrometry, Mass Spectrometry, Drug Resistance, Mitochondria, Ophthalmic

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