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Thiazine patents



      
           
This page is updated frequently with new Thiazine-related patents. Subscribe to the Thiazine RSS feed to automatically get the update: related Thiazine RSS feeds.

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Date/App# patent app List of recent Thiazine-related patents
04/17/14
20140107109
 Amino-dihydrothiazine and amino-dioxido dihydrothiazine compounds as beta-secretase antagonists and methods of use patent thumbnailnew patent Amino-dihydrothiazine and amino-dioxido dihydrothiazine compounds as beta-secretase antagonists and methods of use
Wherein variables a4, a5, a6, a8, r1, r2, r3, r7 and n of formula i, independently, are defined herein. The invention also provides pharmaceutical compositions comprising the compounds, and corresponding uses of the compounds and compositions for treatment of disorders and/or conditions related to a-beta plaque formation and deposition, resulting from the biological activity of bace.
04/03/14
20140094454
 Tetrahydropyrrolothiazine compounds patent thumbnailTetrahydropyrrolothiazine compounds
Or a pharmaceutically acceptable salt thereof.. .
03/13/14
20140073815
 Aminodihydrothiazine derivatives substituted with a cyclic group patent thumbnailAminodihydrothiazine derivatives substituted with a cyclic group
Which is useful for treating diseases induced by production, secretion and/or deposition of amyloid β protein.. .
03/06/14
20140066451
 Thioxanthene derivatives for the treatment of infectious diseases patent thumbnailThioxanthene derivatives for the treatment of infectious diseases
The claimed subject matter is directed to certain thioxanthene derivatives and phenothiazine derivatives suitable for use as anti-infective agents, in particular, for the treatment of infectious diseases. The claimed subject matter furthermore relates to compositions including said anti-infective agents..
03/06/14
20140066437
 Oxathiazine derivatives which are substituted with benzyl or heteromethylene groups, method for producing them, their use as medicine and drug containing said derivatives and the use thereof patent thumbnailOxathiazine derivatives which are substituted with benzyl or heteromethylene groups, method for producing them, their use as medicine and drug containing said derivatives and the use thereof
The invention relates to the compounds of formula (i) and to the physiologically acceptable salts thereof. Said compounds are suitable e.g.
02/13/14
20140045828
 Amino-oxazines and amino-dihydrothiazine compounds as beta-secretase modulators and methods of use patent thumbnailAmino-oxazines and amino-dihydrothiazine compounds as beta-secretase modulators and methods of use
Wherein a1, a2, a3, a4, a5, a6, r2, r7, x, y and z of formula i are defined herein. The invention also includes use of these compounds in pharmaceutical compositions for treatment, prophylactic or therapeutic, of disorders and conditions related to the activity of beta-secretase protein.
01/23/14
20140024584
 Tetrasubstituted oxathiazine derivatives, method for producing them, their use as medicine and drug containing said derivatives and the use thereof patent thumbnailTetrasubstituted oxathiazine derivatives, method for producing them, their use as medicine and drug containing said derivatives and the use thereof
The invention relates to the compounds of formula (i) and to the physiologically acceptable salts thereof. Said compounds are suitable e.g.
01/09/14
20140011802
 Fused aminodihydrothiazine derivatives patent thumbnailFused aminodihydrothiazine derivatives
The present invention relates to a fused aminodihydrothiazine derivative of formula (i): wherein r is hydrogen or c1-6 alkyl, optionally substituted by one to five halogen atoms; n is 0, 1, 2 or 3; ar is phenyl or a 5- or 6-membered heteroaromatic group containing 1, 2 or 3 n atoms, which ar is optionally substituted by one to three substituents selected from hal, hydroxyl, —cn, c1-6alkyl, c2-3alkenyl, c2-3alkynyl,c-6alkoxy, c3-6cycloalkoxy and pyrazine, where c1-6alkyl and c1-6alkoxy are optionally substituted by one to three halogen atoms; and pharmaceutically acceptable salts thereof; which compound has an aβ production inhibitory effect or a bace1 inhibitory effect and is useful as a prophylactic or therapeutic agent for a neurodegenerative disease 1 caused by aβ and typified by alzheimer-type dementia.. .
12/26/13
20130345207
 Benzyl-oxathiazine derivatives substituted with adamantane and  noradamantane, medicaments containing said compounds and use thereof patent thumbnailBenzyl-oxathiazine derivatives substituted with adamantane and noradamantane, medicaments containing said compounds and use thereof
The invention relates to compounds of formula (i) and to the physiologically compatible salts thereof. Said compounds are suitable, for example, for treating hyperglycemia..
12/26/13
20130345128
 Oxathiazine derivatives substituted with carbocycles or heterocycles, method for producing same, drugs containing said compounds, and use thereof patent thumbnailOxathiazine derivatives substituted with carbocycles or heterocycles, method for producing same, drugs containing said compounds, and use thereof
The invention relates to the compounds of formula (i) and physiologically acceptable salts thereof. The compounds are suitable, e.g., for treating hyperglycemia..
12/26/13
20130345127
Novel substituted phenyl-oxathiazine derivatives, method for producing them, drugs containing said compounds and the use thereof
The invention relates to the compounds of formula (i) and to the physiologically acceptable salts thereof. Said compounds are suitable e.g.
12/26/13
20130345126
Branched oxathiazine derivatives, method for the production thereof, use thereof as medicine and drug containing said derivatives and use thereof
The invention relates to compounds of formula (i) and to the physiologically compatible salts thereof. Said compounds are suitable, for example, for treating hyperglycemia..
12/26/13
20130345125
Di- and tri-substituted oxathiazine derivatives, method for the production thereof, use thereof as medicine and drug containing said derivatives and use thereof
The invention relates to compounds of formula (i) and to the physiologically compatible salts thereof. Said compounds are suitable, for example, for treating hyperglycemia..
12/19/13
20130338150
Di and tri - substituted oxathiazine derivatives, method for the production, method for the production thereof, use thereof as medicine and drug containing said derivatives and use thereof
The invention relates to compounds of formula (i) and to the physiologically compatible salts thereof. Said compounds are suitable, for example, for treating hyperglycemia..
12/19/13
20130338066
Novel substituted phenyl-oxathiazine derivatives, method for producing them, drugs containing said compounds and the use thereof
The invention relates to the compounds of formula (i) and to the physiologically acceptable salts thereof. Said compounds are suitable e.g.
12/12/13
20130331381
Treatment of cancer with dopamine receptor antagonists
Described are methods of treating a cancer comprising administering to a subject in need thereof an effective amount of a dopamine receptor (dr) antagonist. The dr antagonist may be a phenothiazine derivative, such as thioridazine or chlorpromazine.
11/28/13
20130315992
Phenothiazine diaminium salts and their use
The invention relates to compounds of general formula (i): wherein: each of r1 and r9 is independently selected from: —h, c1-4alkyl, c2-4alkenyl, and halogenated c1-4alkyl; each of r3na and r3nb is independently selected from: —h, c1-4alkyl, c2-4alkenyl, and halogenated c1-4alkyl; each of r7na and r7nb is independently selected from: —h, c1-4alkyl, c2-4alkenyl, and halogenated c1-4alkyl; and wherein: each of ra and rb is independently selected from: c1-4alkyl, halogenated c1-4alkyl, and c6-10aryl; or ra and rb are linked to form a group selected from: c1-6 alkylene and c6-10 arylene; and pharmaceutically acceptable salts thereof, which are useful in the treatment of, for example, alzheimer's disease. In other aspects the invention also relates to novel formulations of 3,7-diamino-10h-phenothiazinium salts..
11/28/13
20130315825
Tricyclic heteroaromatic compounds as alpha-synuclein ligands
Derivatives of phenothiazine, phenoxazine, and phenazine compounds and their use as α-synuclein ligands are described. Also described are methods of using these compounds and their radiolabeled analogs for the detection, monitoring, and treatment of synucleinopathies, including parkinson's disease..
11/14/13
20130303755
Aminodihydrothiazine derivatives
Its pharmaceutically acceptable salt, or a solvate thereof.. .
11/14/13
20130300281
Copolymers for luminescence enhancement in reflective display applications
Copolymers for luminescent enhancement in reflective display applications comprise a functionalized fluorene moiety, including a functional group selected from water-soluble functional groups and/or alcohol-soluble functional groups, and a heterocyclic ring moiety selected from the group consisting of substituted carbazole derivatives, substituted benzothiadiazole derivatives, and substituted phenothiazine derivatives, wherein the respective substituted derivatives include a functional group selected from water-soluble functional groups and/or alcohol-soluble functional groups. Composite materials comprising the copolymers and photoluminescent dyes are also provided, as is a luminescence-based sub-pixel (100)..
10/31/13
20130289023
Method for treating brain tumor
The preset invention relates to a new method for treating brain tumor with an antipsychotic phenothiazine derivative as a brain tumor cell inhibitor or a brain tumor stem cell inhibitor. In particular, an antipsychotic phenothiazine is accessible to brain via blood-brain barrier, which should be beneficially in treatment of brain tumor..
10/03/13
20130261111
Tetrahydropyrrolothiazine compounds
Or a pharmaceutically acceptable salt thereof.. .
10/03/13
20130261069
Pesticidal mixtures comprising isoxazoline derivatives
The present invention provides pesticidal mixtures comprising a component a, a component b and a component c, wherein component a is a compound of formula (i) wherein one of y1 and y2 is s, so or so2 and the other is ch2; l is a direct bond or methylene; a1 and a2 are c—h, or one of a1 and a2 is c—h and the other is n; r1 is hydrogen or methyl; r2 is chlorodifluoromethyl or trifluoromethyl; r3 is 3,5-dibromo-phenyl, 3,5-dichloro-phenyl, 3,4-dichloro-phenyl, or 3,4,5-trichloro-phenyl; r4 is methyl; r5 is hydrogen; or r4 and r5 together form a bridging 1,3-butadiene group; component b is a compound selected from sedaxane, fludioxonil, metalaxyl, mefenoxam, cyprodinil, azoxystrobin, tebuconazole, difenoconazole, thiabendazole, fluopyram, penflufen, n-[9-(dichloromethylene)-1,2,3,4-tetrahydro-1,4-methanonaphthalen-5-yl]-3-(difluoromethyl)-1-methyl-1h-pyrazole-4-carboxamide and fuxapyroxad; or component b is a compound selected from tefluthrin, lambda-cyhalothrin, abamectin, spinosad, spinetoram, chlorpyrifos, thiodicarb, chlorantraniliprole, cyantraniliprole, bacillus firmus, bacillus subtilis, pasteuria spp. Such as p.
08/08/13
20130203741
Fused aminodihydrothiazine derivatives
Or a pharmaceutically acceptable salt thereof or a solvate thereof, wherein ring a is a c6-14 aryl group or the like, l is —nreco— or the like (wherein re is a hydrogen atom or the like), ring b is a c6-14 aryl group or the like, x is a c1-3 alkylene group or the like, y is a single bond or the like, z is a c1-3 alkylene group or the like, r1 and r2 are each independently a hydrogen atom or the like, and r3, r4, r5 and r6 are independently a hydrogen atom, a halogen atom or the like, has an aβ production inhibitory effect or a bace1 inhibitory effect and is useful as a prophylactic or therapeutic agent for a neurodegenerative disease caused by aβ and typified by alzheimer-type dementia.. .
08/08/13
20130203740
Fused aminodihydrothiazine derivatives
Which compound has an aβ production inhibitory effect or a bace1 inhibitory effect and is useful as a prophylactic or therapeutic agent for a neurodegenerative disease caused by aβ and typified by alzheimer-type dementia.. .
08/01/13
20130197244
Methods and compounds useful in the synthesis of fused aminodihydrothiazine derivatives
Provided are compounds and methods useful for the preparation of compounds useful as inhibitors of beta-site amyloid precursor protein (app)-cleaving enzyme.. .
07/18/13
20130184268
2-(r2-thio)-10-[3-(4-r1-piperazin-1-yl) propyl]-10h-phenothiazine for treating a beta-amyloidopathy or an alpha-synucleopathy, and method for the diagnosis or prediagnosis thereof
The invention relates to 2-(r2-thio)-10-[3-(4-r1-piperazin-1-yl)propyl]-10h-phenothiazine according to general formula i, for treating a β-amyloidopathy or an α-synucleinopathy accompanied by a cerebral protein deposit and a reduced activity of the cerebral abcc1-transporter. The invention also relates to a method for the diagnosis or prediagnosis of a β-amyloidopathy or an α-synucleopathy accompanied by a cerebral protein deposit and a reduced activity of the cerebral abcc1-transporter, or for determining the risk of a proband suffering from such an illness, the proband already having accumulated substances transported by the cerebral abcc1 transporter..
06/27/13
20130164381
Nanoparticle-based targeted drug delivery for in vivo bone loss mitigation
The present invention is directed to nanoparticle-based targeted drug delivery system for treatment of bone-loss. An enantiomeric phenothiazine is formulated into an in-vivo nanoparticle delivery system which may contain bone-targeting functionality.
06/20/13
20130158260
Aminodihydrothiazine derivatives
Its pharmaceutically acceptable salt, or a solvate thereof.. .
06/06/13
20130143055
Radically polymerizable phenothiazine macromonomer for use in the coating of medical devices
The present invention is directed to phenothiazine-base macromonomer compounds and methods of making the same.. .
05/23/13
20130126350
Mediator for test sensor
A method of forming a 3-phenylimino-3h-phenothiazine or a 3-phenylimino-3h-phenoxazine mediator includes providing a first reactant including phenothiazine or phenoxazine, providing a first solvent, providing a second reactant and providing a second solvent. The first reactant, first solvent, second reactant and second solvent are combined to form a reactants solution.
04/18/13
20130096107
Use of aminodihydrothiazines for the treatment or prevention of diabetes
Wherein r1 to r3 are as defined herein, as well as pharmaceutically acceptable salts thereof, pharmaceutical compositions containing such compounds and methods for using such compounds for the treatment or prevention of diabetes, particularly type 2 diabetes.. .
03/21/13
20130072602
Process for the preparation of polyether carbonate polyols
The present invention relates to a process for the preparation of polyether carbonate polyols by catalytic copolymerization of carbon dioxide (co2) with alkylene oxides in the presence of one or more h-functional starter substances with the aid of double metal cyanide (dmc) catalysts and in the presence of additives a) chosen from the group consisting of sterically non-hindered phenols, catechols, pyrocatechols, thiazines, phenothiazines, thiazoles, benzothiazoles, oxazines, phenoxazines, 2,2,6,6-tetramethylpiperidine 1-oxyl and nitrostyrenes and optionally in the presence of metal salts b).. .
03/14/13
20130065887
Treatment of cancer with dopamine receptor antagonists
Described are methods of treating a cancer comprising administering to a subject in need thereof an effective amount of a dopamine receptor (dr) antagonist. The dr antagonist may be a phenothiazine derivative, such as thioridazine or chlorpromazine.
01/10/13
20130012388
Pyrazinothiazines having herbicidal action
In which the variables are defined according to the description, processes and intermediates for preparing the compounds of the formula i and their n oxides, their agriculturally useful salts, compositions comprising them and their use as herbicides, and also a method for controlling unwanted vegetation.. .
01/03/13
20130005575
Pyridothiazines having herbicidal action
In which the variables are defined according to the description, processes and intermediates for preparing the compounds of the formula i and their n-oxides, their agriculturally suitable salts, compositions comprising them and their use as herbicides, and also methods for controlling unwanted vegetation.. .
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20120203020

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20120122880

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20120070503

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20120042856

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Thiazine topics: Phenothiazine, Pharmaceutically Acceptable Salt, Prophylactic, Degenerative Disease, Neurodegenerative Disease, Antipsychotic, Brain Tumor, Penthiopyrad, Streptomyces, Isoxazoline, Cyantraniliprole, Insecticide, Imidacloprid, Chlorpyrifos, Cyprodinil

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This listing is a sample listing of patents related to Thiazine for is only meant as a recent sample of applications filed, not a comprehensive history. There may be associated servicemarks and trademarks related to these patents. Please check with patent attorney if you need further assistance or plan to use for business purposes. This patent data is also published to the public by the USPTO and available for free on their website. Note that there may be alternative spellings for Thiazine with additional patents listed. Browse our RSS directory or Search for other possible listings.
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