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Therapeutics

Therapeutics-related patent applications - as published by the U.S. Patent and Trademark Office (USPTO).


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NEW Method for determining the level of hypoxia in a tumor
Academisch Ziekenhuis Maastricht
June 22, 2017 - N°20170176445

The invention is in the field of medicine and molecular therapeutics. The invention provides means and measures for diagnosis and treatment, in particular for diagnosis and treatment of tumors, more in particular for determining the level of hypoxia in a tumor and for reducing the risk of metastasis of a tumor in a subject. The invention comprises a method wherein ...
NEW Assays for detecting neutralizing autoantibodies to biologic therapy
Nestec S.a.
June 22, 2017 - N°20170176433

The present invention provides assays for detecting and measuring the presence or level of neutralizing and non-neutralizing autoantibodies to biologics such as anti-tnfα drug therapeutics in a sample. The present invention is useful for monitoring the formation of neutralizing and/or non-neutralizing anti-drug antibodies over time while a subject is on biologic therapy. The present invention is also ...
NEW Inhibition of bruton's tyrosine kinase (btk) in the lung to treat severe lung inflammation and ...
Board Of Regents, The University Of Texas System
June 22, 2017 - N°20170175125

Bruton's tyrosine kinase (btk) plays an important role in the pathophysiology of local inflammation in acute lung injury (ali)/acute respiratory distress syndrome (ards). A unique two hit model of ali induced by lipopolysaccharide (lps)/immune complex (ic)—was developed, along with viral-induced ali caused by influenza virus and copd caused by second hand smoke. Two types or therapeutics (...
NEW Therapeutics Patent Pack
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Therapeutics Patent Applications
Download 307+ Therapeutics-related PDFs
For professional research & prior art discovery
inventor
  • 307+ full patent PDF documents of Therapeutics-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
NEW Polypeptides, antibody variable domains and antagonists
Domantis Limited
June 22, 2017 - N°20170174775

The invention relates to anti-tnfr1 polypeptides and antibody single variable domains (dabs) that are resistant to degradation by a protease, as well as antagonists comprising these. The polypeptides, dabs and antagonists are useful for as therapeutics and/or prophylactics that are likely to encounter proteases when administered to a patient, for example for pulmonary administration, oral administration, delivery to the ...
NEW Use of fluorinated derivatives of 4-aminopyridine in therapeutics and medical imaging
The University Of Chicago
June 22, 2017 - N°20170174629

The present disclosure provides novel compounds, including compounds that bind to potassium channels, methods for their manufacture, and methods for their use, including their use to diagnose and/or assess traumatic brain injury and use to treat dymeylinating diseases, and/or in vivo imaging of the central neverous system, and to diagnose and/or assess the progression of ms or ...
NEW Novel non-invasive method for direct delivery of therapeutics to the spinal cord in the treatment ...
United States Department Of Veterans Affairs
June 22, 2017 - N°20170173307

Most spinal cord therapies are administered systemically, with only a small portion of the therapeutic reaching the spinal cord. A novel method for delivering therapeutics directly to the spinal cord is provided. The method uses a duel-balloon catheter to isolate the microvasculature around a region of the spinal cord. Once isolated, one or more therapeutics are delivered directly to the ...
NEW Therapeutics Patent Pack
Download 307+ patent application PDFs
Therapeutics Patent Applications
Download 307+ Therapeutics-related PDFs
For professional research & prior art discovery
inventor
  • 307+ full patent PDF documents of Therapeutics-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
Clathrin replacement therapeutics
Regents Of The University Of Minnesota
June 15, 2017 - N°20170165324

The invention in suitable embodiments is directed to replacement therapeutics. In one aspect, a medicament is comprised in whole or in part of one or more clathrin heavy chain protein that is formed from a plurality of isolated, synthetic or recombinant clathrin protein molecules. In one embodiment, a man-made clathrin heavy chain protein composition replaces and/or modifies cell elements ...
Oncolytic rhabdovirus
Turnstone Limited Patnership
June 15, 2017 - N°20170165305

Embodiments of the invention include compositions and methods related to non-vsv rhabdoviruses and their use as anti-cancer therapeutics. Such rhabdoviruses possess tumor cell killing properties in vitro and in vivo.
Compositions and methods for the delivery of therapeutics
The Board Of Regents Of The University Of Nebraska
June 15, 2017 - N°20170165271

The present invention provides compositions and methods for the delivery of antivirals to a cell or subject.
Antibody cytokine engrafted compositions and methods of use for immunoregulation
Novartis Ag
June 08, 2017 - N°20170158747

The present disclosure provides antibody cytokine engrafted proteins that bind to and stimulate intracellular signaling through interleukin 10 receptor. Provided antibody cytokine engrafted proteins find use in enhancing anti-inflammatory cell responses, and reducing pro-inflammatory effects in the treatment, amelioration and prophylaxis of immune related disorders. Additionally provided are polynucleotides and vectors that encode antibody cytokine engrafted proteins and host cells capable ...
Modulators of pharmacokinetic properties of therapeutics
Novartis Ag
June 08, 2017 - N°20170158647

Or a pharmaceutically acceptable salt, solvate, and/or ester thereof, compositions containing such compounds, therapeutic methods that include the administration of such compounds, and therapeutic methods and include the administration of such compounds with at least one additional therapeutic agent.
Capcna peptide therapeutics for cancer
Rll, Llc
June 08, 2017 - N°20170157210

Administration of compositions comprising cell-permeable cancer-specific proliferating cell nuclear antigen derived peptides and their variants reduces the proliferation of cancer cells and also augments cytotoxic effects of chemotherapeutics. The compositions are effective in cells harboring mutations in dna repair proteins.
Treatment of pervasive developmental disorders with redox-active therapeutics
Edison Pharmaceuticals, Inc.
June 08, 2017 - N°20170157065

Methods of treating or suppressing pervasive developmental disorders (pdds) including; autistic disorder, asperger's syndrome, childhood disintegrative disorder (cdd), rett's disorder, and pdd-not otherwise specified (pdd-nos) or attention deficit/hyperactivity disorder (adhd) comprising administering to a subject in need thereof a therapeutically effective amount of one or more compounds as disclosed herein.
Therapeutics Patent Pack
Download 307+ patent application PDFs
Therapeutics Patent Applications
Download 307+ Therapeutics-related PDFs
For professional research & prior art discovery
inventor
  • 307+ full patent PDF documents of Therapeutics-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
Pan-her antibody composition
Symphogen A/s
June 01, 2017 - N°20170152322

The present invention is directed to improved therapeutics against receptors within the egfr/erbb/her family that more broadly interfere with multiple members of the her family (pan-her inhibition). More particularly, the invention is directed to the use of antibody compositions for human cancer therapy. In vitro studies have shown that the antibody compositions of the invention targeting multiple her ...
Methods of curing hbv infection and providing complete protection against hbv infection
Symphogen A/s
June 01, 2017 - N°20170152303

Disclosed are the methods of curing hbv infection and providing complete protection against hbv infection in a simplified hbv immunization schedule. The mechanistic basis for curing hbv infection is founded on the understanding that hepatitis b virus infection is established and prolonged by new rounds of infection with continuously produced viruses, which are not fully neutralized because of insufficient endogenous ...
Compositions and methods for treating cancer
The General Hospital Corporation
June 01, 2017 - N°20170151345

The technology described herein is directed to methods and compositions directed to the treatment of cancer, e. G. Using multifunctional receptor targeted cancer therapeutics.
Methods and products for transfecting cells
Factor Bioscience Inc.
June 01, 2017 - N°20170151285

The present invention relates in part to nucleic acids encoding proteins, nucleic acids containing non-canonical nucleotides, therapeutics comprising nucleic acids, methods, kits, and devices for inducing cells to express proteins, methods, kits, and devices for transfecting, gene editing, and reprogramming cells, and cells, organisms, and therapeutics produced using these methods, kits, and devices. Methods for inducing cells to express proteins ...
Glycan therapeutics and related methods thereof
Kaleido Biosciences, Inc.
June 01, 2017 - N°20170151269

Preparations of glycan therapeutics, pharmaceutical compositions and medical foods thereof, optionally comprising micronutrients, polyphenols, prebiotics, probiotics, or other agents are provided and methods of making same. Also provided are methods of using said glycan therapeutics, e. G. For the modulation of human gastrointestinal microbiota and to treat dysbioses.
Glycan therapeutics and related methods thereof
Kaleido Biosciences, Inc.
June 01, 2017 - N°20170151268

Preparations of glycan therapeutics, pharmaceutical compositions and medical foods thereof, optionally comprising micronutrients, polyphenols, prebiotics, probiotics, or other agents are provided and methods of making same. Also provided are methods of using said glycan therapeutics, e. G. For the modulation of human gastrointestinal microbiota and to treat dysbioses.
Lin28/let-7 crystal structures, purification protocols, and molecular probes suitable for screening assays and therapeutics
Kaleido Biosciences, Inc.
May 25, 2017 - N°20170145420

The invention provides compositions and methods for regulating microrna (mirna) biogenesis. The invention also relates to compositions and methods for treating or preventing cancer in a subject in need thereof.
Composition and methods of use of nano anti-radical therapeutics to inhibit cancer
Kaleido Biosciences, Inc.
May 25, 2017 - N°20170143844

This invention relates to the compositions and methods of use of macromolecular nitroxide as a nano anti-radical therapy (nanoart) to compliment current chemotherapy, radiotherapy, immunotherapy, hormonal therapy, biological therapy and surgery in the treatment of cancer. Nanoart is unique in that it inhibits all three key steps in carcinogenesis. Nanoart inhibits proliferation, progression and metastasis of cancer processes through the ...
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