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Therapeutics

Therapeutics-related patent applications - as published by the U.S. Patent and Trademark Office (USPTO).


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Antibody therapeutics that bind cd38
Sorrento Therapeutics, Inc.
October 12, 2017 - N°20170291959

There is disclosed compositions and methods relating to or derived from anti-cd38 antibodies. More specifically, there is disclosed fully human antibodies that bind cd38, cd38-antibody binding fragments and derivatives of such antibodies, and cd38-binding polypeptides comprising such fragments. Further still, there is disclosed nucleic acids encoding such antibodies, antibody fragments and derivatives and polypeptides, cells comprising such polynucleotides, ...
Antibody therapeutics that bind cd123
Sorrento Therapeutics, Inc.
October 12, 2017 - N°20170291949

There is disclosed compositions and methods relating to or derived from anti-cd123 antibodies. More specifically, there is disclosed fully human antibodies that bind cd123, cd123-antibody binding fragments and derivatives of such antibodies, and cd123-binding polypeptides comprising such fragments. Further still, there is disclosed nucleic acids encoding such antibodies, antibody fragments and derivatives and polypeptides, cells comprising such polynucleotides, ...
Chimeric antigen receptor-expressing t cells as anti-cancer therapeutics
Purdue Research Foundation
October 12, 2017 - N°20170290900

Cytotoxic lymphocytes expressing chimeric antigen receptors (car) that target and bind small conjugate molecules (scm) are disclosed, as well as methods of using the cells and the scms in the treatment of cancer.
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Therapeutics Patent Applications
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  • 307+ full patent PDF documents of Therapeutics-related inventions.
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Drug repositioning methods for targeting breast tumor initiating cells
The Methodist Hospital Research Institute
October 05, 2017 - N°20170286630

Disclosed are systems biology-based methods for repositioning known pharmaceutical compounds to new indications, through the identification of network-based signatures. In particular, the invention provides new and useful methods for selecting drugs or combinations of drugs (and preferably previously-approved drugs) for use in new therapeutic indications. Also disclosed are methods for identifying anti-breast tumor initiating cell (tic)-based therapeutics from within ...
Method and system for microbiome-derived diagnostics and therapeutics
Ubiome, Inc.
October 05, 2017 - N°20170286620

A method for diagnosing and treating an immune microbial dysfunction in a subject, the method comprising: receiving an aggregate set of biological samples from a population of subjects; generating at least one of a microbiome composition dataset and a microbiome functional diversity dataset for the population of subjects; generating a characterization of the immune microbial dysfunction based upon features extracted ...
Method and system for microbiome-derived diagnostics and therapeutics
Ubiome, Inc.
October 05, 2017 - N°20170286619

A method for diagnosing and treating an immune microbial dysfunction in a subject, the method comprising: receiving an aggregate set of biological samples from a population of subjects; generating at least one of a microbiome composition dataset and a microbiome functional diversity dataset for the population of subjects; generating a characterization of the immune microbial dysfunction based upon features extracted ...
Therapeutics Patent Pack
Download 307+ patent application PDFs
Therapeutics Patent Applications
Download 307+ Therapeutics-related PDFs
For professional research & prior art discovery
inventor
  • 307+ full patent PDF documents of Therapeutics-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
Predicting allergic reactions
Alcyomics Ltd
October 05, 2017 - N°20170285001

This present invention provides a method of predicting immunogenicity and hypersensitivity or allergic reactions to chemical compounds, therapeutics, cosmetics and other chemical compositions. The method uses an in vitro assay employing autologous blood derived cells and an autologous cultured skin biopsy and is of particular utility in the identification and prediction of skin sensitizers that cause allergic contact dermatitis.
Methods and therapeutics relating to mrna biomarkers for clinical prognosis of cancer
Duke University
October 05, 2017 - N°20170283882

This disclosure provides methods and compositions of matter relating to the monitoring of relative concentrations of pairs of isoforms of mrna or downstream expression products thereof. The methods can include measuring a relative expression level of a pair of mrna isoforms or downstream expression products thereof and comparing the relative expression level to relative historical or cohort expression levels of ...
Compositions and methods to selectively block pain induced by cold
University Of Southern California
October 05, 2017 - N°20170281756

Tissue injury prompts the release of a number of proalgesic molecules that induce acute and chronic pain by sensitizing pain-sensing neurons (nociceptors) to heat and mechanical stimuli. In contrast, many proalgesics have no effect on cold sensitivity, or can inhibit cold-sensitive neurons and diminish cooling-mediated pain-relief (analgesia). Nonetheless, cold pain (allodynia) is prevalent in many inflammatory and neuropathic pain settings, ...
Cholix toxin-derived fusion moelcules for oral delivery of biologically active cargo
Applied Molecular Transport, Llc
October 05, 2017 - N°20170281736

The present disclosure relates to pharmaceutical compositions comprising a non-naturally occurring fusion molecule and one or more pharmaceutically acceptable carriers, formulated for oral delivery to a subject, and designed to provide for improved, effective therapies for treatment of, e. G., inflammatory diseases, autoimmune diseases, cancer, metabolic disorders, and growth deficiency disorders. The present disclosure relates to a non-toxic mutant form ...
Blt2 agonists for the treatment of pain
Fraunhofer-gesellschaft Zur FÖerderung Der Angewandten Forschung E.v.
October 05, 2017 - N°20170281575

The present invention pertains to novel analgesics useful for treating pain. Blt2 agonists were found to desensitize trpv1 mediated signaling in sensory neurons. Thus the invention provides blt2 agonists as novel pain therapeutics. Additional aspects of the invention pertain to combinations of blt2 agonists with blt1 antagonists for treating pain in subjects. Pharmaceutical compositions and kits comprising the new analgesics ...
Method and system for microbiome-derived diagnostics and therapeutics for neurological health issues
Ubiome, Inc.
September 28, 2017 - N°20170277848

A method for at least one of characterizing, diagnosing and treating a neurological health issue in at least a subject, the method comprising: receiving an aggregate set of biological samples from a population of subjects; generating at least one of a microbiome composition dataset and a microbiome functional diversity dataset for the population of subjects; generating a characterization of the ...
Method and system for microbiome-derived diagnostics and therapeutics for neurological health issues
Ubiome, Inc.
September 28, 2017 - N°20170277847

A method for at least one of characterizing, diagnosing and treating a neurological health issue in at least a subject, the method comprising: receiving an aggregate set of biological samples from a population of subjects; generating at least one of a microbiome composition dataset and a microbiome functional diversity dataset for the population of subjects; generating a characterization of the ...
Therapeutics Patent Pack
Download 307+ patent application PDFs
Therapeutics Patent Applications
Download 307+ Therapeutics-related PDFs
For professional research & prior art discovery
inventor
  • 307+ full patent PDF documents of Therapeutics-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
Method and system for microbiome-derived diagnostics and therapeutics for neurological health issues
Ubiome, Inc.
September 28, 2017 - N°20170277845

A method for at least one of characterizing, diagnosing and treating a neurological health issue in at least a subject, the method comprising: receiving an aggregate set of biological samples from a population of subjects; generating at least one of a microbiome composition dataset and a microbiome functional diversity dataset for the population of subjects; generating a characterization of the ...
Method and system for microbiome-derived diagnostics and therapeutics for neurological health issues
Ubiome, Inc.
September 28, 2017 - N°20170277844

A method for at least one of characterizing, diagnosing and treating a neurological health issue in at least a subject, the method comprising: receiving an aggregate set of biological samples from a population of subjects; generating at least one of a microbiome composition dataset and a microbiome functional diversity dataset for the population of subjects; generating a characterization of the ...
Method and system for microbiome-derived diagnostics and therapeutics for neurological health issues
Ubiome, Inc.
September 28, 2017 - N°20170277843

A method for at least one of characterizing, diagnosing and treating a neurological health issue in at least a subject, the method comprising: receiving an aggregate set of biological samples from a population of subjects; generating at least one of a microbiome composition dataset and a microbiome functional diversity dataset for the population of subjects; generating a characterization of the ...
Methods of producing patient-specific anti-cancer therapeutics and methods of treatment therefor
Berkeley Lights, Inc.
September 28, 2017 - N°20170276679

A method of preparing an antibody therapeutic is provided comprising: (a) providing a dissociated cell sample from at least one solid tumor sample obtained from a patient; (b) loading the dissociated cell sample into a microfluidic device having a flow region and at least one isolation region fluidically connected to the flow region; (c) moving at least one b cell ...
Methods and compositions related to prostate cancer therapeutics
The Johns Hopkins University
September 28, 2017 - N°20170275673

Disclosed herein are compositions and methods for detecting biological molecules and biomarkers associated with prostate cancer. Disclosed herein are compositions and methods for detecting biological molecules and biomarkers associated with castration-resistant prostate cancer wherein such biological molecules and biomarkers comprise androgen-receptor splice variants that can be used to develop effective therapeutic regimens for prostate cancer patients. Disclosed herein are methods ...
Endosomal escape domains for delivery of macromolecules into cells
The Regents Of The University Of California
September 28, 2017 - N°20170275650

The disclosure provides fusion polypeptides and constructs useful for delivering diagnostics and therapeutics to cells. The fusion constructs include a protein transduction domain, a endosomal escape domain and a cargo domain. Also provided are methods of treating disease and disorders such as cell proliferative disorders.
Multivalent cd20-binding molecule comprising shiga toxin a subunit effector polypeptides and enriched compositions therefof
Molecular Templates, Inc.
September 28, 2017 - N°20170275382

The present invention provides multivalent cd20-binding molecules, and compositions thereof, such as enriched compositions comprising large proportions of multivalent cd20-binding molecule relative to monovalent cd20-binding molecule. Certain multivalent cd20-binding molecules of the present invention comprise 1) two or more cd20 binding regions and 2) one or more shiga toxin effector polypeptide regions derived from an a subunit of ...
Method and system for microbiome-derived diagnostics and therapeutics
Ubiome, Inc.
September 21, 2017 - N°20170270272

A method for diagnosing and treating an immune microbial dysfunction in a subject, the method comprising: receiving an aggregate set of biological samples from a population of subjects; generating at least one of a microbiome composition dataset and a microbiome functional diversity dataset for the population of subjects; generating a characterization of the immune microbial dysfunction based upon features extracted ...
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