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Therapeutics

Therapeutics-related patent applications - as published by the U.S. Patent and Trademark Office (USPTO).


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Compositions and methods for therapeutics prescreening
Technion Research & Development Foundation Ltd.
August 17, 2017 - N°20170233823

A theranostic composition and method for determining the cell-specific potency of drugs is provided. Further, compositions and methods useful for studying the therapeutic profile of one or more drugs within a cell microenvironment, including but not limited to a tumor, are provided.
Multiple target nucleic acid detection method using clamping probe and detection probe
Panagene Inc.
August 17, 2017 - N°20170233818

The present invention relates to an application of a target nucleic acid detection method using a clamping probe and a detection probe. The method of the present invention can effectively detect a small amount of variation or a specific gene sequence contained in a sample by selective amplification and detection of a trace amount of a target gene to be ...
Antibody therapeutics that bind ctla4
Sorrento Therapeutics, Inc.
August 17, 2017 - N°20170233476

There is disclosed compositions and methods relating to or derived from anti-ctla4 antibodies. More specifically, there is disclosed fully human antibodies that bind ctla4, ctla4-antibody binding fragments and derivatives of such antibodies, and ctla4-binding polypeptides comprising such fragments. Further still, there is disclosed nucleic acids encoding such antibodies, antibody fragments and derivatives and polypeptides, cells comprising such polynucleotides, ...
Therapeutics Patent Pack
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Therapeutics Patent Applications
Download 307+ Therapeutics-related PDFs
For professional research & prior art discovery
inventor
  • 307+ full patent PDF documents of Therapeutics-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
Protein/oligonucleotide core-shell nanoparticle therapeutics
Northwestern University
August 17, 2017 - N°20170232109

The present disclosure is directed to core-shell nanoparticles, compositions comprising core-shell nanoparticles, and methods of their use.
Formulations for histatin therapeutics
Rapid Pathogen Screening, Inc.
August 17, 2017 - N°20170232064

Histatins may be used for skin wound healing in humans and other animals. For example, histatins could be included in gels, ointments, creams, tissue glues, patches, aerosol sprays, subcutaneous injections, subcutaneous infusions, intradermal injections, intradermal infusions, or any combination of these formulations. In some embodiments, peptide fragments from at least two different histatins are used.
Compounds for use in treating acute coronary syndrome and related conditions
Vitae Pharmaceuticals, Inc.
August 17, 2017 - N°20170231992

Provided herein are compounds and pharmaceutically acceptable salts thereof that are useful therapeutics for acute coronary syndrome and related disorders.
Therapeutics Patent Pack
Download 307+ patent application PDFs
Therapeutics Patent Applications
Download 307+ Therapeutics-related PDFs
For professional research & prior art discovery
inventor
  • 307+ full patent PDF documents of Therapeutics-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
Aptamers for binding flavivirus proteins
National University Of Singapore
August 10, 2017 - N°20170226511

The present invention relates to nucleic acids. In particular, it relates to aptamers capable of binding to a flavivirus structural protein or a flavivirus non-structural protein, useful as therapeutics for preventing, treating and/or diagnosing a flavivirus infection in a patient.
Compositions and methods to regulate renalase in the treatment of diseases and disorders
Yale University
August 10, 2017 - N°20170226228

The invention provides compositions and methods for binding and inhibiting renalase. In one embodiment, the renalase binding molecule inhibits renalase activity. Thus, in diseases and conditions where a reduction of renalase activity is beneficial, such inhibitory renalase binding molecules act as therapeutics.
Antibody therapeutics that bind cd137
Sorrento Therapeutics, Inc.
August 10, 2017 - N°20170226215

There is disclosed compositions and methods relating to or derived from anti-cd137 antibodies. More specifically, there is disclosed fully human antibodies that bind cd137, cd137-antibody binding fragments and derivatives of such antibodies, and cd137-binding polypeptides comprising such fragments. Further still, there is disclosed nucleic acids encoding such antibodies, antibody fragments and derivatives and polypeptides, cells comprising such polynucleotides, ...
Potent dual brd4-kinase inhibitors as cancer therapeutics
H. Lee Moffitt Cancer Center And Research Institute, Inc.
August 10, 2017 - N°20170226065

Disclosed herein are compounds that are inhibitors of brd4 and their use in the treatment of cancer. Methods of screening for selective inhibitors of brd4 are also disclosed. In certain aspects, disclosed are compounds of formula i-iv.
Antrodia camphorata and ganoderma lucidum composition having functionality to inhibit renal cancer cell growth and ...
Taipei Medical University
August 10, 2017 - N°20170224752

The present invention provides an antrodia camphorata and ganoderma lucidum composition having functionality to inhibit renal cancer cell growth and enhance kidney function. This navel composition is constituted of water-soluble base material, plasticity-increasing base material, antrodia camphorata extract, ganoderma lucidum extract, and auxiliary enzyme. Differing from the conventional therapeutics treating the glomerulonephritis by administering high-dosage steroid for 1-4 months, the ...
Mucoadhesive carriers of particles, method of preparation and uses thereof
Globalacorn Ltd.
August 10, 2017 - N°20170224612

The present invention relates to a mucoadhesive carrier system, for particles, which comprises nanoscaffold having a nanofibrous layer with a thickness of from 0. 1 to 1000 μm, carrying a substance in the form of particles. The mucoadhesive layer, in at least a part of its surface, overlaps the nanoscaffold. A process for its preparation and its use for delivery of ...
Substrate clearance assays for lysosomal enzymes
Shire Human Genetic Therapies, Inc.
August 03, 2017 - N°20170219566

The present invention provides, among other things, improved substrate clearance assays for lysosomal enzyme that are particularly useful for measuring potency of lysosomal enzymes or other therapeutics for treatment of lysosomal storage diseases. In particular, the present invention combines a physiologically relevant substrate cell assay and an efficient scintillation based detection method.
Therapeutics Patent Pack
Download 307+ patent application PDFs
Therapeutics Patent Applications
Download 307+ Therapeutics-related PDFs
For professional research & prior art discovery
inventor
  • 307+ full patent PDF documents of Therapeutics-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
Methods to produce a human plasma-derived igg preparation enriched in brain disease-related natural iggs
Baxalta Gmbh
August 03, 2017 - N°20170218051

The present invention provides, among other aspects, methods for the manufacture of plasma-derived immunoglobulin g compositions highly enriched for anti-brain disease related protein antibodies (e. G., anti-aβ, anti-rage, and anti-α-synuclein antibodies). Advantageously, the methods provided do not affect the manufacturing processes or capabilities for producing plasma-derived igg therapeutics. Plasma-derived igg compositions that are highly enriched ...
Cyclin based inhibitors of cdk2 and cdk4
University Of South Carolina
August 03, 2017 - N°20170218018

Structural and functional analysis of peptide inhibitor binding to the cyclin d and cyclin a groove has been investigated and used to design peptides that provide the basis for structure-activity relationships, have improved binding and have potential for development as chemical biology probes, as potential diagnostics and as therapeutics in the treatment of proliferative diseases including cancer and inflammation.
Delivery molecules for therapeutics
Marina Biotech, Inc.
August 03, 2017 - N°20170216227

Activity-generating delivery molecules comprising the structure r3—(c═o)-xaa-nh—r4 wherein xaa is any d- or l-amino acid residue with a non-hydrogen, substituted or unsubstituted side chain, r3—(c═o)— and —nh—r4 are independently a long chain group, each long chain group containing one or more carbon-carbon double bonds, and ...
Zwitterionic hydrogels for delivery of biomolecules
University Of Massachusetts
July 27, 2017 - N°20170209625

The invention provides a novel approach in which zwitterionic networks are used to sequester and deliver ionic biomolecules, such as proteins, without compromising their native conformation and bioactivity. Zwitterionic networks are designed to effectively retain and deliver ionic or polar biomolecules for guided tissue regeneration. The invention represents a conceptual advance and enables a novel strategy for the utilization of ...
Selective serotonin 2a/2c receptor inverse agonists as therapeutics for neurodegenerative diseases
Acadia Pharmaceuticals Inc.
July 27, 2017 - N°20170209424

Behavioral pharmacological data with the compound of formula (i), a novel and selective 5ht2a/2c receptor inverse agonist, demonstrate in vivo efficacy in models of psychosis and dyskinesias. This includes activity in reversing mk-801 induced locomotor behaviors, suggesting that this compound may be an efficacious anti-psychotic, and activity in an mptp primate model of dyskinesias, suggesting efficacy as an ...
A combination of kynurenine and antigen presenting cells (apc) as therapeutics and methods for their ...
The University Of British Columbia
July 27, 2017 - N°20170209401

This invention provides combinations of kynurenine and antigen presenting cells (apc) for modulating immune tolerance, wherein the combinations may be used to modulate an autoimmune response, which may be of use in the treatment of type 1 diabetes (t1d) or alopecia areata (aa). Uses of kynurenine and antigen presenting cells (apc) as an immune modulator for the treatment of t1...
Process for encapsulating soluble biologics, therapeutics, and imaging agents
The Trustees Of Princeton University
July 27, 2017 - N°20170209386

An “inverse” precipitation route to precipitate aqueous soluble species with copolymers as nanoparticles having a hydrophilic, polar core and a less polar shell is described. A method of the invention for encapsulating water soluble molecules using rapid, controlled precipitation is presented. Water soluble molecules—including peptides, proteins, dna, rna, non-biologic therapeutics, polysaccharide-based therapeutics (e. G., ...
Materials with water-triggered drug-release properties for localized therapeutics
The Trustees Of Princeton University
July 27, 2017 - N°20170209382

Methods, devices, and/or systems for providing a three-dimensional printing of a structure encapsulating a drug comprising at least one zn(ii) complexed with acrylate groups capable of forming a 3d structure and capable of encapsulating a drug.
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