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Therapeutical

Therapeutical-related patent applications - as published by the U.S. Patent and Trademark Office (USPTO).


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Presentation of bioactive proteins
Indiana University Research And Technology Corporation
November 09, 2017 - N°20170321220

The invention provides a fusion protein comprising an antigen binding domain linked to a bacteriophage decoration (dec) protein along with a polynucleotide comprising the nucleic acid sequence of the fusion protein and a vector comprising the polynucleotide. Additionally, the invention provides a composition comprising the fusion protein and a virus-like particle (vlp), and a method of treating a disease in ...
Methods for diagnosing and treating cd1d restricted gamma/delta t cell lymphomas
Centre National De La Recherche Scientifique (cnrs)
November 09, 2017 - N°20170320951

Methods for diagnosing and treating cd1d-restricted gamma/delta t cell lymphomas are disclosed. In particular, the present disclosure relates to a method for diagnosing a t cell lymphoma as a cd1d-restricted gamma/delta t cell lymphoma in a patient in need thereof including i) detecting the presence of cd1d restricted gamma/delta t lymphoma cells in a ...
Anti-cd3 antibodies, bispecific antigen-binding molecules that bind cd3 and cd20, and uses thereof
Regeneron Pharmaceuticals, Inc.
November 09, 2017 - N°20170320948

The present invention provides antibodies that bind to cd3 and methods of using the same. According to certain embodiments, the antibodies of the invention bind human cd3 with high affinity and induce human t cell proliferation. The invention includes antibodies that bind cd3 and induce t cell-mediated killing of tumor cells. According to certain embodiments, the present invention provides bispecific ...
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Therapeutical Patent Applications
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Use of agonists of formyl peptide receptor 2 for treating ocular inflammatory diseases
Allergan, Inc.
November 09, 2017 - N°20170320897

The present invention relates to a method for treating ocular inflammatory diseases in a subject in need of such treatment, which comprises administering a pharmaceutical composition comprising a therapeutically effective amount of at least one agonist of formyl peptide receptor 2.
Production of encapsulated nanoparticles at high volume fractions
Iceutica Pty Ltd.
November 09, 2017 - N°20170320030

The present invention relates to methods for producing particles of a biologically active material using dry milling processes as well as compositions comprising such materials, medicaments produced using said biologically active materials in particulate form and/or compositions, and to methods of treatment of an animal, including man, using a therapeutically effective amount of said biologically active materials administered by ...
Valerian composition and related methods
Physician's Seal, Llc
November 09, 2017 - N°20170319697

A valerian composition includes a therapeutically effective pharmaceutical dosage form having a solid core including a polymer in which valerian and a valerian stability improving amount of an acidifying agent are contained. The valerian stability improving amount of acidifying agent being sufficient to impart a ph of 2 to 5 to the polymer.
Therapeutical Patent Pack
Download 734+ patent application PDFs
Therapeutical Patent Applications
Download 734+ Therapeutical-related PDFs
For professional research & prior art discovery
inventor
  • 734+ full patent PDF documents of Therapeutical-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
Methylphenidate extended release chewable tablet
Tris Pharma, Inc.
November 09, 2017 - N°20170319566

An oral methylphenidate extended release tablet is described, which can be scored and still retain its extended release profile. The tablet contains a combination of an uncoated methylphenidate—ion exchange resin complex, a barrier coated methylphenidate—ion exchange resin complex—matrix, and an uncomplexed methylphenidate active component. Following administration of a single dose of the extended release ...
Compositions and methods for extended therapy with aminopyridines
Acorda Therapeutics, Inc.
November 09, 2017 - N°20170319562

Disclosed herein are methods and compositions related to use of aminopyridines, such as 4-aminopyridine, for use in a therapeutically effective manner for patients with a demyelinating condition, such as multiple sclerosis.
Methods of treating hepatorenal syndrome and hepatic encephalopathy with thromboxane-a2 receptor antagonists
Cumberland Emerging Technologies, Inc.
November 09, 2017 - N°20170319554

The present invention is directed to methods of treating hepatorenal syndrome by administration of a therapeutically effective amount of a thromboxane a2 receptor antagonist to a patient in need thereof. The present invention is also directed to methods of treating hepatic encephalopathy and cerebral edema by administration of a therapeutically effective amount of a thromboxane a2 receptor antagonist to a ...
Composition and method for treating neuronal ceroid lipofuscinosis
Rush University Medical Center
November 09, 2017 - N°20170319531

Provided herein are methods for treatment of a neurodegenerative disease, such as neuronal ceroid lipofuscinosis including administering to a subject in need of such treatment a composition comprising a therapeutically effective amount of an agent that mediates upregulation of tpp1.
Compounds and methods for modulating vascular injury
The Regents Of The University Of California
November 09, 2017 - N°20170319529

Methods of modulating healing response to vascular injury and/or vascular scarring in a subject are provided. As such, aspects of the disclosure relate to the use of pro-resolving lipid mediators to modulate inflammation and/or restenosis of a vascular wall. Another aspect of the disclosure relates to the use of pro-resolving lipid mediators to modulate a biological activity of ...
Floating zinc gastric delivery compositions
Physician's Seal, Llc
November 09, 2017 - N°20170319476

A composition includes a therapeutically effective oral pharmaceutical dosage form that becomes buoyant upon contact with gastric fluid. The dosage form includes an active ingredient combination including an amino acid source and a zinc source, an anionic polymer, an effervescent agent, and a ph buffer. The dosage form is effective for releasing the active ingredient combination while buoyant on gastric ...
Implantable cellular and biotherapeutic agent delivery canister
Nanovault Medical, Llc
November 09, 2017 - N°20170319472

The invention relates to a metallic, nanoporous canister used to encapsulate cellular and/or biotherapeutic agents. The device is biocompatible and functions to wholly isolate a therapeutically active agent and/or cells therein. Their implantation, and survival in vivo, permits the local or systemic diffusion of their encapsulated cellular and/or biomolecular and therapeutics factors with the potential to promote ...
Therapeutical Patent Pack
Download 734+ patent application PDFs
Therapeutical Patent Applications
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For professional research & prior art discovery
inventor
  • 734+ full patent PDF documents of Therapeutical-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
Methods and compositions pertaining to human cerebral cavernous malformations
University Of Tennessee Research Foundation
November 02, 2017 - N°20170313779

The disclosure is based on the discovery that aberrant immune responses are contributing to the pathogenicity of ccms in patients, and that blocking those responses treats the ccm. Described herein is a method for treating ccms in a patient in need thereof comprising administering a therapeutically effective amount of a b-cell immunomodulation therapy to the patient.
6-aminopyridin-3-yl thiazoles as modulators of roryt
University Of Tennessee Research Foundation
November 02, 2017 - N°20170313691

The invention also comprises a method of treating or ameliorating a syndrome, disorder or disease, wherein the syndrome, disorder or disease is rheumatoid arthritis or psoriasis. The invention also comprises a method of modulating rorγt activity in a mammal by administration of a therapeutically effective amount of at least one compound of formula i.
Histone deacetylase inhibitors and uses thereof
University Of Tennessee Research Foundation
November 02, 2017 - N°20170313688

Provided herein are compounds of the formula (i) as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of cancer. Additionally, provided is a method for treating cancer, comprising the step of administering a therapeutically effective amount of a compound ...
Compounds and methods for the treatment of cystic fibrosis
University Of Tennessee Research Foundation
November 02, 2017 - N°20170313659

The invention relates to a compound of formula i and methods of treating cystic fibrosis comprising the step of administering a therapeutically effective amount of a compound of formula i or ia to a patient in need thereof:
3,4-diaminobenzenesulfonamide derivatives for inhibiting cell death
University Of Tennessee Research Foundation
November 02, 2017 - N°20170313653

This disclosure relates to a novel class of compounds having the structure of formula i as defined herein and pharmaceutical compositions comprising a compound of formula i or a pharmaceutically acceptable salt thereof. This disclosure also comprises methods of treating a subject by administering a therapeutically effective amount of a compound of formula i or a pharmaceutically acceptable salt thereof ...
Method for the synthesis of hydroxy-triglycerides and uses thereof for the prevention and treament of ...
University Of Tennessee Research Foundation
November 02, 2017 - N°20170313646

The present invention relates to hydroxy-triglycerides, their synthesis, a pharmaceutical and/or nutraceutical composition which comprises at least one of said hydroxy-triglycerides, and a method which comprises the administration to a patient of a therapeutically effective quantity of at least one of said hydroxy-triglycerides or at least one of said pharmaceutical and/or nutraceutical compositions, for the prevention and/or ...
Systems and methods for the treatment of pain through neural fiber stimulation
University Of Tennessee Research Foundation
November 02, 2017 - N°20170312523

Embodiments of the present invention provide systems and methods for the treatment of pain through activation of select neural fibers. The neural fibers may comprise one or more afferent neural fibers and/or one or more efferent neural fibers. If afferent fibers are stimulated, alone or in combination with efferent fibers, a therapeutically effective amount of electrical stimulation is applied ...
Methods for treating patients with familial hypercholesterolemia
University Of Tennessee Research Foundation
November 02, 2017 - N°20170312359

The present invention provides methods for treating patients suffering from familial hypercholesterolemia, including both hefh and hofh. The methods of the invention provide for lowering at least one lipid parameter in the patient by administering a therapeutically effective amount of an antibody or antigen-binding fragment thereof that specifically binds to angptl3 in combination with a therapeutically effective amount of a ...
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