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Therapeutical

Therapeutical-related patent applications - as published by the U.S. Patent and Trademark Office (USPTO).


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NEW Aptamers against glioma cells
University Of Central Lancashire
May 17, 2018 - N°20180135052

Provided are aptamers able to bind to ligands associated with cancer cells. The ligands may particularly be associated with brain cancers, such as gliomas. The aptamers may be used therapeutically for the prevention and/or treatment of such cancers. Aptamers may be associated with anti-cancer agents, or with detection moieties. Also provided as pharmaceutical compositions and methods of treatment employing ...
NEW Rnai inhibitors of glucose-6-phosphate dehydrogenase for treating cardiovascular and pulmonary conditions
May 17, 2018 - N°20180135049

The present disclosure provides for methods of treating or preventing a cardiovascular disorder and/or a related pulmonary disorder in a subject. In certain embodiments, a therapeutically effective amount of a polynucleotide inhibitor of glucose-6-phosphate dehydrogenase (g6pd) or a nucleic acid encoding g6pd is administered.
NEW Methods and pharmaceutical compositions (ntsr1 inhibitors) for the treatment of hepatocellular carcinomas
Universite Paris Descartes
May 17, 2018 - N°20180134788

The present disclosure relates to methods and pharmaceutical compositions for the treatment of hepatocellular carcinomas (hcc in abbreviation, the term “hepatocellular carcinoma” has its general meaning in the art and refers to the cancer developed in hepatocytes see page 2 lines 24-30 of the present application) comprising administering to the subject a therapeutically effective amount of an ...
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NEW Synergistic nanotherapy systems and methods of use thereof
Duke University
May 17, 2018 - N°20180133319

The presently disclosed subject matter is directed to a method of treating cancer, such as (but not limited to) metastatic bladder and breast cancer. The disclosed method comprises using two treatment modalities to synergistically treat primary and secondary tumor cells in a subject. The first element of the method comprises administering a therapeutically effective amount of a plasmonics-active metal nanoparticle ...
NEW Methods and compositions for treating herpes
Genocea Biosciences, Inc.
May 17, 2018 - N°20180133310

The present disclosure provides, inter alia, certain combinations of immunogenic compositions (e. G., vaccines) against hsv-2 and antiviral therapy. The vaccines can be used therapeutically and/or prophylactically.
NEW Vaccine against porcine parvovirus
Boehringer Ingelheim Vetmedica Gmbh
May 17, 2018 - N°20180133309

The present invention relates to a porcine parvovirus (ppv) viral protein 2 (vp2) having at amino acid position 228 a glutamic acid residue or a glutamate residue, and/or at amino acid position 414 a serine residue, and/or at amino acid position 419 a glutamine residue, and/or at amino acid position 436 a threonine residue. Further, the present invention relates to immunogenic compositions ...
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Therapeutical Patent Applications
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  • 734+ full patent PDF documents of Therapeutical-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
NEW Compositions, methods and therapies for administering antigen peptide
May 17, 2018 - N°20180133299

The invention relates to compositions, methods and therapies for the treatment of inflammation caused by infection with propionibacterium acnes. The compositions include a combination of peptide and anti-tnf. The peptide consists of a specific amino acid sequence or a peptide consisting of an amino acid sequence derived the specific amino acid sequence by deletion, substitution, insertion or addition of one ...
NEW Method of treating low blood pressure
The George Washington University A Congressionally Chartered Not-for-profit Corporation
May 17, 2018 - N°20180133282

A method for treating a patient suffering from one of septic shock, acute kidney injury, severe hypotension, cardiac arrest, and refractory hypotension, but not from myocardial infarction, is provided. The method includes administering a therapeutically effective dose of angiotensin ii, or ang ii, to the patient.
NEW Compositions and methods for treating diabetes, hypertension and hypercholesterolemia
Imagine Pharma
May 17, 2018 - N°20180133280

The present invention provides a composition comprising a therapeutically effective amount of a polypeptide, peptide, or analog corresponding to one or more of seq id no(s) 1, 2, 3 or 4, and or more of a pharmaceutically acceptable carrier, pharmaceutically acceptable diluent, and/or pharmaceutically acceptable excipient. The polypeptide therapeutic of the present invention may be formulated for administration to a subject in ...
NEW Treatment of pain using placental stem cells
Anthrogenesis Corporation
May 17, 2018 - N°20180133261

Provided herein are methods of treatment of an individual having pain, e. G., neuropathic pain, comprising administering to the individual a therapeutically effective amount of tissue culture plastic adherent placental stem cells (pdac™).
NEW Therapeutic ozone agent and treatment
May 17, 2018 - N°20180133248

The use of a medical therapeutic ozone agent in vivo to treat a variety of disorders including, but not limited to hypoxic conditions, autoimmune disease, fibrotic disease, inflammatory disease, neurodegenerative disease, infectious disease, lung disease, heart and vascular disease, metabolic disease, and cancer, wherein the therapeutic ozone agent is administered in a therapeutically effective amount, which can convert carbon monoxide ...
NEW Method for treating cancer
Epizyme, Inc.
May 17, 2018 - N°20180133224

The present invention provides a method for treating or alleviating a symptom of a disorder, e. G., immune evasion, cancer-cell induced immune dysfunction, reduced immune response, lowered inflammation, decreased expression of a major histocompatibility complex (mhc), or cancer, characterized by aberrant, misregulated, or increased enhancer of zeste homolog 2 (ezh2) activity in a cell or subject in need thereof by contacting ...
NEW Combination therapy with a phosphoinositide 3-kinase inhibitor with a zinc binding moiety
May 17, 2018 - N°20180133223

Or a pharmaceutically acceptable salt thereof, wherein r is hydrogen or an acyl group; and (b) a bcl-2 inhibitor; wherein the compound of formula i or pharmaceutically acceptable salt thereof and a bcl-2 inhibitor are administered in amounts which in combination are therapeutically effective. The invention further provides a pharmaceutical composition comprising a compound of formula i or a pharmaceutically ...
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Therapeutical Patent Applications
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  • 734+ full patent PDF documents of Therapeutical-related inventions.
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NEW Methods and compositions for treating gastric ulcers
Luoda Pharma Pty Limited
May 17, 2018 - N°20180133201

A method of treating and/or preventing gastric ulcers, said method comprising administering by injection a therapeutically effective amount of a composition comprising: c) a first agent selected from the group consisting of: a medium chain triglyceride and a long chain triglyceride; and d) a second agent comprising a proton pump inhibitor or pharmaceutically or veterinary acceptable salt, wherein the ...
NEW Compositions and methods comprising celecoxib or related compounds and dextromethorphan
Antecip Bioventures Ii Llc
May 17, 2018 - N°20180133195

Neurological disorders may be treated by administering a therapeutically effective amount of dextromethorphan and a therapeutically effective amount of a compound such as celecoxib that inhibits the metabolism of dextromethorphan, to a person in need thereof. The two compounds may be administered separately, or in a single dosage form or composition as described herein.
Methods of treating with tumor membrane vesicle-based immunotherapy and predicting therapeutic response thereto
Emory University
May 10, 2018 - N°20180128833

Disclosed herein is a method for treating a subject having, or at risk of having, a triple negative breast cancer, comprising administering to the subject a therapeutically effective amount of an immunotherapeutic agent and a tumor membrane vesicle (tmv), wherein the tmv comprises a lipid membrane, and a b7-1 and/or il-12 molecule anchored to the lipid membrane. Also ...
Bortezomib-based delivery system
Nanosilical Devices S.r.i.
May 10, 2018 - N°20180127441

The invention relates to a class of molecules obtained for conjugating a species or substrate to bortezomib by means of bonds of the boronic diester type which are stable in a neutral environment but which are capable of being degraded in a slightly acid environment (ph=4. 5-5. 0) releasing the drug bortezomib and which can also be conjugated on the surface ...
Tetrasubstituted alkene compounds and their use
Eisai R&d Management Co., Ltd.
May 10, 2018 - N°20180127378

Disclosed herein are compounds, or pharmaceutically acceptable salts thereof, and methods of using the compounds for treating breast cancer by administration to a subject in need thereof a therapeutically effective amount of the compounds or pharmaceutically acceptable salts thereof. The breast cancer may be an er-positive breast cancer and/or the subject in need of treatment may express a mutant ...
Tricyclic sulfones as ror gamma modulators
May 10, 2018 - N°20180127368

Or stereoisomers, tautomers, pharmaceutically acceptable salts, solvates, or prodrugs thereof, wherein all substituents are defined herein. Also provided are pharmaceutical compositions comprising the same. Such compounds and compositions are useful in methods for modulating rorγ activity in a cell and methods for treating a subject suffering from a disease or disorder in which the subject would therapeutically benefit ...
Pharmaceutical compositions and dosage forms for administration of hydrophobic drugs
Lipocine Inc.
May 10, 2018 - N°20180125979

Pharmaceutical compositions and dosage forms for administration of hydrophobic drugs, particularly steroids, are provided. The pharmaceutical compositions include a therapeutically effective amount of a hydrophobic drug, preferably a steroid; a solubilizer, preferably a vitamin e substance; and a surfactant. The synergistic effect between the hydrophobic drug and the vitamin e substance results in a pharmaceutical formulation with improved dispersion of ...
Compositions containing ambient-temperature stable, inactivated but therapeutically active biopharmaceuticals & methods for formulation thereof
Universal Stabilization Technologies, Inc.
May 10, 2018 - N°20180125966

The disclosure concerns compositions containing inactivated but therapeutically active biopharmaceuticals, and methods for formulation thereof. Biopharmaceuticals are encapsulated and immobilized in dry amorphous carbohydrate-glass and irradiated for inactivation while in the dry state. The resulting compositions provide ambient-temperature stable, therapeutically active but inactivated biopharmaceuticals for use in vaccines and other applications.
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