|| List of recent Surfactant-related patents
|Liquid formulation containing a protein drug|
Disclosed is a method of preparing a stabilized liquid formulation of a protein drug, comprising admixing a protein drug with a composition for stabilization, wherein the composition for stabilization comprises a surfactant, a buffer, and a liquid medium, and has a ph from about 5 to about 8.. .
|Continuous latex production processes|
Processes for continuously producing latex emulsions are disclosed. A multi-screw extruder is used for the production of the emulsion.
|Pharmaceutical composition comprising a poorly water-soluble active ingredient, a surfactant and a water-soluble polymer|
Solid composition comprising (a) an anionic surfactant in combination with a water-soluble and basic polymer, or (b) a cationic surfactant in combination with a water-soluble and acidic polymer, and (c) at least one poorly water-soluble pharmaceutically active ingredient, and solid or liquid dosage forms, especially tablets, coated tablets, capsules or suppositories or aqueous solutions comprising the solid composition. The surfactant/polymer system is soluble in water and solubilises the active ingredient so that good bioavailability with therapeutical quantities may be attained.
|Surfactant for stabilizing water/supercritical carbon dioxide microemulsion|
(where r1 is a c6-30 hydrocarbon group having a branched chain; and m is a hydrogen atom, an alkali metal, ammonium, a basic amino acid residue, an alkanolamine residue having a c2-3 hydroxyalkyl group, or an aliphatic alkanolammonium) for stabilizing a water/supercritical carbon dioxide microemulsion.. .
|Vehicle-glass cleaning fluid composition comprising anionic surfactant and tartaric acid|
The present invention relates to a vehicle-glass cleaning fluid composition comprising an alcohol, an anionic surfactant, and tartaric acid as a corrosion inhibitor. The present invention provides a cleaning fluid composition entailing improved metal corrosion prevention, durability for rubbers and plastics, and performance in preventing the noise and wear which occur when there is friction between a wiper blade and glass surface.
|Method for sterilizing microbial cells using polyethylene glycol-based nonionic surfactant|
A method for sterilizing microbial cells is provided. According to the method, microbial cells or a culture containing microbial cells are treated with a polyethylene glycol-based nonionic surfactant so that almost all of the microbial cells are sterilized while the enzyme activity expressed in the microbial cells is maintained at a high level.
|Non-ionic acid-labile surfactants and methods of use|
Wherein r1 is independently selected from c2-c10 alkyl or substituted alkyl, r2 is independently selected from the group consisting of —h and c1-c6 alkyl or substituted alkyl, x is selected from the group consisting of —nh— and —o—, y is a carbohydrate, and m is an integer from 1 to 8. The compound may comprise a non-ionic acid labile surfactant.
|Compositions, methods and systems for polymerase chain reaction assays|
The present disclosure provides methods, devices, systems and compositions for detecting nucleic acids in polymerase chain reaction assays, such as droplet digital polymerase chain reaction (ddpcr) assays. The present disclosure provides methods, devices, systems and compositions for detecting nucleic acids in ddpcr assays using intercalating dyes.
|Continuous wax dispersion production processes|
Processes for continuously producing a wax dispersion are disclosed. A multi-screw extruder is used for the processes.
|Pressure-sensitive adhesive composition, and pressure-sensitive adhesive sheet|
Provided is a water-dispersible acrylic pressure-sensitive adhesive composition which can form a pressure-sensitive adhesive layer excellent in antistatic property, repeeling property (light peeling property), and appearance property. The repeelable water-dispersible acrylic pressure-sensitive adhesive composition of the present invention contains an acrylic emulsion-based polymer composed of 70 to 99.5% by weight of a (meth)acrylic acid alkyl ester and 0.5 to 10% by weight of a carboxyl group-containing unsaturated monomer as monomer components, a crosslinking agent, an ionic compound, and a nonionic surfactant with an hlb value of 6 or more..
|Methods of coating a construct with methylated collagen|
A double-structured tissue implant and a method for preparation and use thereof for implantation into tissue defects. The double-structured tissue implant comprising a primary scaffold and a secondary scaffold consisting of a soluble collagen solution in combination with a non-ionic surfactant generated and positioned within the primary scaffold.
|Ophthalmic aqueous composition|
The present invention provides an ophthalmic aqueous composition having an oil-in-water emulsion including a vegetable oil, a non-ionic surfactant, and a terpenoid, wherein an average particle diameter of emulsion particles is within the range of 30 nm to 300 nm.. .
|Oxidizing bleach composition|
The invention provides an aqueous bleaching solution for substrate treatment. The aqueous bleaching solution features a source of oxidant and a plurality of optically functional nanoparticles.
|Cosmetic composition comprising silica aerogel particles, a gemini surfactant and a solid fatty substance|
In which r1 and r3 denote, independently of one another, an alkyl radical containing from 1 to 25 carbon atoms; r2 denotes a spacer consisting of a linear or branched alkylene chain containing from 1 to 12 carbon atoms; x and y denote, independently of one another, a —(c2h4o)a—(c3h6o)bz group; n ranges from 1 to 10 ; and (3) at least one fatty phase comprising at least one fatty substance chosen from solid fatty substances and pasty fatty substances. The composition in accordance with the invention makes it possible to make good the lack of cutaneous lipids in dehydrated skin, and to provide comfort and persistent nutrition, while at the same time having sensory properties, for example a non-greasy and non-tacky effect and a matt skin appearance, and also good skin penetration properties, even with a high level of solid fatty substance..
|Hair care composition comprising a pre-emulsified formulation|
A hair care composition comprising from about 0.25% to about 80% of a pre-emulsified emulsion comprising from about 0.005% to about 80% of one or more materials selected from the group comprising metathesized unsaturated polyol esters, sucrose polyesters, fatty esters with a molecular weight greater than or equal to 1500 and mixtures thereof and mixtures thereof or, by weight of said hair care composition; wherein an emulsifier is selected from the group consisting of anionic, non-ionic, cationic, amphoteric and mixtures thereof wherein the average particle size of the pre-emulsified oil in water emulsion is from about 20 nanometers to 20 microns; and a cationic surfactant system wherein the composition is stable with respect to one of the following measures selected from emulsion particle size, viscosity or visual phase separation and mixtures thereof.. .
|Ophthalmic composition containing cyclosporine and method for preparing same|
The present invention relates to an ophthalmic composition containing cyclosporine as an active ingredient and comprising propylene glycol, a surfactant, and purified water, and to a method for preparing same. The ophthalmic composition according to the present invention is in the form of a clear and transparent solution, and increases patient compliance due to the absence of side effects, such as cloudy vision or a scorching sensation, and has a high bioavailability due to improved cyclosporine absorbance in the ocular tissue, which is the target organ..
|Methods and compositions for live attenuated viruses|
Embodiments herein relate to compositions of and methods for live viruses. In certain embodiments, a live, attenuated virus composition includes, but is not limited to, one or more live, attenuated viruses and compositions to reduce inactivation and/or degradation of the live, attenuated virus.
|Manufacture of vaccines that contain both hepatitis b virus surface antigen and surfactant|
When preparing hbsag for use in a combination vaccine, it is known to add a non-ionic detergent after the hbsag has been purified. Adding detergents after purification of hbsag is not optimal, however, as it requires a separate processing step during manufacture.
|Pharmaceutical compositions of lipase-containing products, in particular of pancreatin|
Orally administrable pharmaceutical compositions of lipase-containing products, particularly pancreatin and pancreatin-containing products, or of enzyme products which contain at least one lipase of non-animal, especially microbial origin, which improve the lipolytic activity and particularly result in stabilization of the lipase in the acidic ph range. These oral pharmaceutical compositions contain a system which includes at least one surfactant and one co-surfactant and optionally a lipophilic phase, and are self-emulsifiable on contact with a hydrophilic and a lipophilic phase.
|Cleaning agent having high conditioning effectiveness|
The invention relates to a cosmetic cleaning agent including in a cosmetically acceptable carrier a) at least one anionic surfactant, b) at least one amphoteric and/or zwitterionic surfactant of the following formula (i), in which—r denotes a straight-chain or branched, saturated or mono- or polyunsaturated alkyl or alkenyl residue having 8 to 24 carbon atoms, and—r1 and r2 independently of one another denote the groups —(ch2)n—coox, —(ch2)n—o—(ch2)n—coox or —(ch2)n—oh, wherein n is an integer from 1 to 4 and x is an alkali, an alkaline-earth, an ammonium or an alkanolamine ion, c) at least one silicone of the following formula (ii), in which—the residue r denotes a hydrogen atom, an alkyl group having 1 to 12 c atoms, an alkoxy group having 1 to 12 c atoms or a hydroxyl group,—x denotes a number from 1 to 100,—y denotes a number from 1 to 20, and—a and b independently of one another denote numbers from 0 to 50, and d) at least one cationic polymer selected from quaternized cellulose derivatives.. .
|Enamel protectant and repair brushing gels|
Substantially aqueous-free, enamel protectant and repair brushing gels containing: stannous fluoride, calcium and a substantivity agent comprising: an emulsion of polydimethylsiloxane in a nonionic surfactant, wherein substantivity of said stannous fluoride and calcium into biofilm present on enamel is enhanced through calcium binding shifting from bidentate to monodentate in the presence of stannous fluoride; and said brushing gels have substantially improved, enamel protectant factor (epf) and enamel repair factor (erf) values compared to fluoride brushing treatments with comparable or higher fluoride levels.. .
|Methods for protecting and reparing enamel|
A method of treatment for enamel with substantially aqueous-free, enamel protectant and repair brushing gels containing: stannous fluoride, calcium and a substantivity agent comprising: an emulsion of polydimethylsiloxane in a nonionic surfactant, wherein substantivity of said stannous fluoride and calcium into biofilm present on enamel is enhanced through calcium binding shifting from bidentate to monodentate in the presence of stannous fluoride; and said brushing gels have substantially improved, enamel protectant factor (epf) and enamel repair factor (erf) values compared to fluoride brushing treatments with comparable or higher fluoride levels.. .
|Flame retardant and fire extinguishing product for fires in solid materials|
A novel flame retardant and fire extinguishing product for preventing and fighting fires in solid materials is disclosed herein. The product is thixotropic and comprises water, one or more flame retardants, one or more stabilizers, and one or more preservatives.
|Method to generate diversion and distribution for unconventional fracturing in shale|
Relatively high viscosity materials and methods for introducing them as discrete bodies or masses into relatively low viscosity fluids, such as brine, give fracturing fluids that help control the diversion and distribution of fluids as they are pumped downhole against a subterranean formation, particularly shale, to fracture it. A wide range of relatively viscous materials may be used, including polymers, crosslinked polymers and/or surfactant gels, for instance gels created with viscoelastic surfactants (vess).
|Compositions and methods for enhancement of production of liquid and gaseous hydrocarbons|
A well treatment composition is well-designed for the simultaneous enhancement of the production of both liquid and gaseous hydrocarbons from the same reservoir on a non-selective basis. The well treatment composition includes a first surfactant and a second surfactant, wherein the second surfactant is selected from the group consisting of ethoxylated alkylene amines, ethoxylated alkyl amines, propoxylated alkylene amines, propoxylated alkyl amines, ethoxylated-propoxylated alkylene amines and ethoxylated-propoxylated alkyl amines.
|Coloring agent having direct dyes and non-ionic surfactants|
The present specification provides an agent for coloring keratinic fibers, wherein it contains (a) at least one compound of formula (i) and (b) at least one non-ionic surfactant. The present disclosure also provides a method of using such an agent as a coloring composition for human hair, wherein the method comprises application of the agent to the hair, an application time of from 5 to 45 minutes, and rinsing the agent from the hair..
|Coloring composition with direct dyes and zwitterionic surfactants|
Agents for coloring keratinic fibers, containing (a) at least one compound of formula (i), and (b) at least one zwitterionic surfactant are disclosed and described.. .
|Coloring agent comprising direct dyes and phosphate surfactants|
Agents for coloring keratinic fibers, containing (a) at least one compound of formula (i) and (b) at least one phosphate surfactant are disclosed and described.. .
|Self-adhesive lavatory treatment compositions|
Within which, r is an c12-c24 aliphatic mono- or poly-alkene moiety, and n has a value of from 1 to 50, an organic solvent constituent, a surfactant, and water.. .
|Solvent-based inkjet ink formulations|
Solvent-based inkjet ink formulations including an organic solvent, a resin, a surfactant, and a colorant are provided. The inks have many desirable attributes such as extended decap time..
|Method for manufacturing emulsion|
The disclosed invention is a method for producing an emulsion, comprising the steps of: (1) causing water and a water-insoluble substance that is to be emulsified to become freely miscible under conditions of temperature and pressure in the vicinity of the vapor-liquid critical point of water; and (2) cooling the product comprised of the water-insoluble substance and water solved each other in the presence of a surfactant to obtain a liquid comprised of the water-insoluble substance dispersed in water or a liquid comprised of water dispersed in the water-insoluble substance. The present invention provides a new method for producing emulsions with high efficiency without requiring a long period of processing or a great amount of energy..
|Antimicrobial cleaning composition|
The present invention relates to an antimicrobial cleaning composition comprising at least one sugar surfactant and a compound of the formula (i) as biocide, and to the use of the sugar surfactants for improving the activity of the biocide.. .
|Cationic micelles with anionic polymeric counterions compositions thereof|
The invention relates to polymer-micelle complex. The polymer-micelle complexes include a positively charged micelle selected from the group consisting of a monomeric quaternary ammonium compound, a monomeric biguanide compound, and mixtures thereof.
|Mesoporous metal oxides and processes for preparation thereof|
A process for preparing a mesoporous metal oxide, i.e., transition metal oxide, lanthanide metal oxide, a post-transition metal oxide and metalloid oxide. The process comprises providing an acidic mixture comprising a metal precursor, an interface modifier, a hydrotropic ion precursor, and a surfactant; and heating the acidic mixture at a temperature and for a period of time sufficient to form the mesoporous metal oxide.
|Manipulation of fluids and reactions in microfluidic systems|
Microfluidic structures and methods for manipulating fluids and reactions are provided. Such structures and methods may involve positioning fluid samples, e.g., in the form of droplets, in a carrier fluid (e.g., an oil, which may be immiscible with the fluid sample) in predetermined regions in a microfluidic network.
|Method for manufacturing electrostatic latent image developing toner|
An electrostatic latent image developing toner is manufactured by mixing an aqueous medium dispersion liquid (x) containing negatively chargeable toner cores and an aqueous medium dispersion liquid (y) containing positively chargeable resin particulates, followed by stirring the mixture liquid to form shell layers each on a surface of the toner cores with the resin particulates. The shell layers are formed with the resin particulates subjected to a stirring treatment together with an anionic surfactant..
|High porosity mesoporous siliceous structures|
A process comprising: a) contacting one or more of sources of silicon oxide, selected from water sol-uble.silica sources arid alkali metal silicates, with an aqueous reaction medium, comprising one or more nonionic surfactants and thereby forming mesoporous structures comprising crosslinked silicon oxide units, wherein said cross-linked silicon oxide units have pores of about 1 to about 100 nanometers and wherein the aqueous reaction medium exhibits a ph of about 0 to about 4.0; b) exposing the aqueous reaction medium containing the mesoporous structures to elevated temperatures for a time sufficient to achieve the desired structure and pore size. Preferred water soluble silica sources comprise silicic acid, or po!ysilicic acids, the aqueous reaction, medium is prepared by combining one or more nonionic surfactants and water, theteby forming an aqueous, reaction medium.
The invention relates to a cosmetic composition comprising an emulsion comprising hydrophobically modified particles, amino functionalized silicone and water; the cosmetic composition further comprising a moisturizing agent and at least one component selected from the group consisting of vitamin, anti-dandruff agent and surfactant, wherein the composition comprises at least a vitamin or anti-dandruff agent. The invention further relates to a method of treating a skin condition comprising the step of topically applying to the skin the cosmetic composition of the invention..
|Novel gold-platinum based bi-metallic nanocrystal suspensions, electrochemical manufacturing processes therefor and uses for the same|
The present invention relates to novel gold-platinum based bi-metallic nanocrystal suspensions that have nanocrystal surfaces that are substantially free from organic or other impurities or films associated with typical chemical reductants/stabilizers and/or raw materials used in nanoparticle formation processes. Specifically, the surfaces are “clean” relative to the surfaces of metal-based nanoparticles made using chemical reduction (and other) processes that require organic (or other) reductants and/or surfactants to grow (and/or suspend) metal nanoparticles from metal ions in a solution.
The present invention relates to lubricious coatings comprising an ionomer and a hydrophilic polymer wherein the ionomer is cross-linked using a suitable cross-linking agent, and optionally also conventional excipients, such as a surfactant, a plasticizer and/or a filler. The invention also relates to pharmaceutical products covered by such lubricious coatings, compositions for preparing these lubricious coatings and a method for providing pharmaceutical products with these lubricious coatings..
|Method for conferring antimicrobial activity to a substrate|
In one embodiment, the invention relates to a method for rendering a non-metallic substrate stably antimicrobial. The method comprises: (a) contacting the substrate with an antimicrobial surfactant; (b) contacting the substrate with a polymeric binder; and (c) subjecting the substrate, surfactant, and binder to conditions at which the substrate becomes stably antimicrobial.
|Aminofunctional silicone emulsions|
Aqueous silicone emulsions are disclosed comprising: a) an aminofunctional organopolysiloxane, b) a quaternary ammonium surfactant having a formula r1 r2 r3 r4 n+ x−, where r1 is an organofunctional group containing at least 10 carbon atoms, r2 is r1 or a hydrocarbyl containing 1 to 12 carbon atoms, r3 is r1, r2, or an alcohol group containing 2 to 10 carbon atoms, r4 is r1, r2, or r3, x− is a halide, sulfate, sulfonate, methosulfate, or ethosulfate, c) a nonionic surfactant, where the aqueous silicone emulsion contains less than 0.2 weight % of d4 and d5 cyclic siloxanes.. .
|Enamel protectant and repair toothpaste treatments|
Substantially aqueous-free, enamel protectant and enamel repair toothpaste treatments containing: stannous fluoride, calcium and a substantivity agent comprising: an emulsion of polydimethylsiloxane in a nonionic surfactant, wherein: (a) substantivity of said stannous fluoride and calcium into biofilm present on enamel is enhanced through calcium binding shifting from bidentate to monodentate in the presence of stannous fluoride; and (b) said toothpaste treatments indicate substantially improved, enamel protectant factor (epf) and enamel repair factor (erf) values compared to fluoride brushing treatments with comparable or higher fluoride levels.. .
|Water-based ink for ink-jet recording, ink cartridge and ink-jet recording apparatus|
A water-based ink for ink-jet recording includes: a pigment; water; 1,2-alkanediol; and a surfactant represented by the following general formula (1): r1con(ch3)ch2ch2r2, wherein in the general formula (1), r1 is a saturated or unsaturated hydrocarbon group having 9 to 19 carbon atoms; the hydrocarbon group is straight chain or branched chain hydrocarbon group; r2 is so3m or coom; and m is li, na or k.. .
|Water-based ink for ink-jet recording, water-based ink set for ink-jet recording, ink cartridge, and ink-jet recording method|
A water-based ink for ink-jet recording includes a pigment; water; an acetylene glycol-based surfactant contained by 0.1% by weight to 0.3% by weight in the water-based ink; tripropylene glycol methyl ether contained by 2.5% by weight to 4.5% by weight in the water-based ink; and tripropylene glycol n-butyl ether contained by 0.5% by weight to 1.5% by weight in the water-based ink.. .
|Fire extinguishing agent and fire extinguishing method using same|
The objective of the present invention is to provide an extinguishing agent which has excellent fire-extinguishing property and which exhibits high safety to the environment and human body. The fire extinguishing agent of the present invention is characterized in comprising a biosurfactant..
|Articles for cleaning a hard surface|
Articles for cleaning debris from a hard surface are described herein, the articles include a hard surface cleaning composition which includes from about 0.1% to about 50% by weight of the composition of a detergent surfactant and a pad including a core and adapted to contact the hard surface. The core comprising up to about 50% cellulosic material.
|Cleaning compositions for cleaning a hard surface|
Cleaning compositions for cleaning debris from a hard surface are described herein, the cleaning compositions include from about 0.001% to about 1% by weight of the composition of a thickener and from about 0.1% to about 50% by weight of the composition of an alkyl sulfate detergent surfactant that contains about 8 carbon atoms on the average, with substantially all of the alkyl groups having within two carbon atoms of the 8 average carbon atoms. They are high sudsing, have excellent soap scum removal and hard water deposit removal properties and are easy to rinse.
|Hair treatment composition|
(d): cationic surfactant.. .
|Hair cleaning composition|
(d): anionic surfactant.. .
|Surfactantless bimetallic nanostructures and method for synthesizing same|
A bimetallic nanowire synthesis method is provided. The method includes adding first and second solutions into a vessel containing a porous template with the first solution containing first and second reagents added on one side of the porous template and the second solution added on an opposite side of the porous template.
|Coloring agent comprising direct dyes and amphoteric surfactants|
Agents for coloring keratinic fibers, containing (a) at least one compound of formula (i) and (b) at least one amphoteric surfactant are disclosed and described.. .
|Method for producing a collagen membrane and uses thereof|
The present invention relates to a method of producing a collagen membrane that has particular mechanical properties. In particular, the present invention relates to a method a of producing a collagen membrane comprising the steps of (i) isolating a collagen-containing tissue and incubating same in an ethanol solution; (ii) incubating the collagen-containing tissue from step (i) in a first solution comprising an inorganic salt and an anionic surfactant in order to denature non-collagenous proteins contained therein; (iii) incubating the collagen-containing tissue produced in step (ii) in a second solution comprising an inorganic acid until the collagen in said material is denatured; and (iv) incubating the collagen-containing tissue produced in step (iii) in a third solution comprising an inorganic acid with simultaneous mechanical stimulation for sufficient time to enable the collagen bundles in said collagen-containing tissue to align; wherein the mechanical stimulation comprises applying tension cyclically to the collagen-containing tissue..
|Structure directed vapour phase polymerisation of conductive polymers|
Disclosed herein is a process for producing a conductive polymer, the process comprising: providing a substrate having an oxidant layer on a surface thereof, the oxidant layer containing an oxidant, a solvent or blend of solvents, and a relatively high molecular weight non-ionic surfactant; exposing the surface containing the oxidant layer to a vapour containing an aryl or heteroaryl monomer that is polymerisable to form a conductive polymer without exposing the oxidant layer to an external source of water vapour; and polymerising the aryl or heteroaryl monomer to form a polyaryl or polyheteroaryl conductive polymer on the surface of the substrate.. .
|Polymerization method using surfactant-containing particle|
L1am2x1b . .
|Methylene beta-ketoester monomers, methods for making methylene beta-ketoester monomers, polymerizable compositions and products formed therefrom|
The present invention provides methylene beta-ketoester monomers, methods for producing the same, and compositions and products formed therefrom. In the method for producing the methylene beta-ketoesters of the invention, a beta-ketoester is reacted with a source of formaldehyde in a modified knoevenagel reaction optionally in the presence of an acidic or basic catalyst, and optionally in the presence of an acidic or non-acidic solvent, to form reaction complex.
|Foam stabilization with polyethyleneimine ethoxylates|
The invention involves foam stabilization compositions that rely upon an electrostatic charge interaction. According to the invention, the positively charged class of polymers such as polyethyleneimine (pei) polymers are used to provide a long range electrostatic interaction with detersive anionic or amphoteric surfactants present in the same.
|Foam stabilization and oily soil removal with associative thickeners|
The invention involves foam stabilization compositions that rely upon anonionic/hydrophobic interaction. According to the invention, an associative thickener is used to provide long range nonionic/hydrophobic interaction with the hydrophobic groups of the surfactants present in the same.
|Post-added builder composition|
A builder that is a post-manufacture addition to detergent compositions includes a total soluble salt content of about 70 wt. % to about 90 wt.
|Hollow spherical zeolite im-5 and preparation method therefor|
The present invention provides a hollow im-5 molecular sieve sphere and the preparation process thereof. The process according to the present invention adds a relatively great amount of the surfactant of a cationic quaternary ammonium salt in the im-5 molecular sieve system, to form a hollow im-5 molecular sieve sphere via the micelle action by the surfactant, which structure benefits the mass transfer of the reaction process..
|System and method for optical detection using capillary action|
A system and method for the detection of one or more analytes in a collected sample employs capillary action in a sample card containing a sample substrate, at least one test capsule and an absorbent pad. The absorbent pad absorbs the contents of the test capsule and delivers the same to the sample substrate, with the contents of the test capsule chemically reacting with at least one detection reagent to establish an optical indicator for the analyte(s).
|Pretreatment solution for immunohistochemical staining and condensed solution thereof|
Disclosed are a pretreatment solution for immunohistochemical staining, which elutes a paraffin-containing embedding medium from a glass slide with a tissue specimen embedded in the medium, and retrieves antigenicity of the tissue specimen, and which is usable three or more times, and a pretreatment solution concentrate for immunohistochemical staining which allows ready preparation of the pretreatment solution and a method of immunohistochemical staining using the same. The pretreatment solution contains an antigen retrieving agent, particular nonionic surfactants, and cyclodextrin or a derivative thereof, with the balance being not less than 80 mass % of water.
|Hydrophilic adhesives and tapes and devices containing the same|
Hydrophilic adhesive compositions are disclosed that contain a surfactant that is miscible, but not fully soluble in the polymer matrix of the adhesive. This permits the surfactant to continuously replenish at the surface of the adhesive as other surfactant is removed, such as when it is carried away by an aqueous sample flowing over that surface in an in-vitro diagnostic device, resulting in adhesive compositions that are inherently hydrophilic on their surfaces and do not rely on the bloom mechanism of known hydrophilic adhesives.
|Method of preparing microspheres by using polymer having sol-gel transition property and microspheres prepared thereby|
The present invention relates to a method of preparing microspheres by using a polymer having a sol-gel transition property and microspheres prepared thereby, and more particularly, to a method of preparing microspheres by using a polymer having a sol-gel transition property and microspheres prepared thereby capable of preventing a solvent in a polymer solution for a carrier from being rapidly diffused to the aqueous medium before formation of the microspheres to reduce porosity of the microspheres and reduce surface roughness of the microspheres in order to obtain microspheres having a sphere shape, and increasing an encapsulation ratio of a bioactive substance, by using a polymer having a sol-gel transition property as a surfactant included in an aqueous medium into which a primary emulsion is injected and gelating a secondary emulsion formed after injecting the primary emulsion using the sol-gel transition property of the polymer used as the surfactant.. .