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Strep patents

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Date/App# patent app List of recent Strep-related patents
 Vaccine against streptococcus pneumoniae patent thumbnailVaccine against streptococcus pneumoniae
The present invention relates to a combination of 2 or more s pneumoniae proteins, their manufacture and use in medicine as a vaccine. Such combinations are particularly useful for the protection of infants and elderly against streptococcal infection..
 Oxidized cardiolipin and uses to detect cardiolipin antibodies patent thumbnailOxidized cardiolipin and uses to detect cardiolipin antibodies
Compositions, methods and devices for the detection of anti-lipoidal antibodies and the diagnosis of disease, for example, syphilis, are described. In particular, oxidized cardiolipins, which may be conjugated with a variety of attachment molecules, such as bsa, klh, biotin, synthetic protein maps, igy, streptavidin, or avidin, are described.
 Electrochemiluminescence immunoassay method patent thumbnailElectrochemiluminescence immunoassay method
Disclosed is an electrochemiluminescence immunoassay method, using a full reaction of a ru(bpy) marked protein-primary antibody, a biotinylated protein-secondary antibody to be tested, and a sample to be tested; addition of a streptavidin-coated magnetic particle to form a complex comprising an antigen, an antibody, and a magnetic particle; adsorption to an electrode surface by the magnetic particle; addition of a dibutyl ethanolamine solution; testing by means of an electrochemical method. Also disclosed is a corresponding electrochemiluminescence immunoassay detection kit..
 Vaccine against streptococcus pneumoniae patent thumbnailVaccine against streptococcus pneumoniae
The present invention relates to improved immunogenic compositions and vaccines, methods for making them and their use in medicine. In particular the invention relates to immunogenic compositions of unconjugated streptococcus pneumoniae proteins selected from: pneumolysin and member(s) of the polyhistidine triad family (e.g.
 Streptococcus bacteriophage lysins for detection and treatment of gram positive bacteria patent thumbnailStreptococcus bacteriophage lysins for detection and treatment of gram positive bacteria
The present invention provides methods, compositions and articles of manufacture useful for the prophylactic and therapeutic amelioration and treatment of gram-positive bacteria, including streptococcus and staphylococcus, and related conditions. The invention provides compositions and methods incorporating and utilizing streptococcus suis derived bacteriophage lysins, particularly plyss2 and/or plyss1 lytic enzymes and variants thereof, including truncations thereof.
 Novel lactic acid bacteria and compositions containing them against bacterial colds patent thumbnailNovel lactic acid bacteria and compositions containing them against bacterial colds
The invention describes a microorganism of the order of lactic acid bacteria or an analogue, fragment, derivative, mutant or combination thereof, wherein the microorganism, or analogue, fragment, derivative, mutant or combination thereof can coaggregate with streptococcus pyogenes.. .
 Therapeutic polyamine compositions and their synthesis patent thumbnailTherapeutic polyamine compositions and their synthesis
This invention relates to a process of synthesis and composition of open chain (ring), closed ring, linear branched and or substituted polyamines, polyamine derived tyrosine phosphatase inhibitors and ppar partial agonists/partial antagonists via a series of substitution reactions and optimizing the bioavailability and biological activities of the compounds. Polyamines prevent the toxicity of neurotoxins and diabetogenic toxins including paraquat, methyphenyl pyridine radical, rotenone, diazoxide, streptozotocin and alloxan.
 Biocontrol formulation containing streptomyces spp., method for preparing the formulation and relevant use patent thumbnailBiocontrol formulation containing streptomyces spp., method for preparing the formulation and relevant use
The present invention is a method for preparing a biocontrol formulation by the following steps. A streptomyces bacterium is selected simultaneously with superior sporulation ability, chitinase activity and antagonistic effectiveness against plant fungal pathogens by culturing with fungal pathogens, wherein the selected streptomyces bacterium is cultured on a chitin-limited plate to assess the ability of sporulation and chitinase activity, and the streptomyces bacterium with superior sporulation ability is the strain with producing powder-like and maturity form spore chains.
 Vaginal compositions based on alkyl polyglucosides patent thumbnailVaginal compositions based on alkyl polyglucosides
Compounds based on alkyl polyglycosides for use in the treatment of streptococcus agalactiae infections and other pathogens are provided. Such compounds may belong to the class of alkyl glucosides or alkyl polyglucosides.
 Streptavidin-coupled magnetic particles and manufacturing method for same patent thumbnailStreptavidin-coupled magnetic particles and manufacturing method for same
The streptavidin-coupled magnetic particle of the present invention, and the streptavidin-coupled magnetic particle manufactured by the manufacturing method of the present invention are useful in clinical diagnosis.. .
Tooth filling materials and dental varnish for inhibiting the formation of a biofilm of streptococcus mutans and the production thereof
There are described tooth filling materials and dental varnishes for inhibiting the biofilm formation of streptococcus mutans containing (a) a quantity of an active substance for inhibiting the biofilm formation, (b) a material for forming a structure for the uptake and delayed release of the active substance and (c) a filling material system. Another aspect of this invention relates to a method for producing tooth filling materials or dental varnishes according to the invention for inhibiting the biofilm formation of streptococcus mutans.
Combination for use in the treatment and/or prevention of mastitis
The present invention relates a combination for use in the treatment and/or prevention of mastitis containing i) an agonistic anti-cd40 monoclonal antibody or a cd40 ligand or a vector coding for the anti-cd40 antibody or a vector coding for the cd40l; and ii) inactivated or attenuated bacteria selected from the group consisting of staphylococcus, streptococcus, listeria or escherichia.. .
C-4" position substituted macrolide derivative
A macrolide compound represented by the formula (i) effective against erythromycin resistant bacteria (for example, resistant pneumococci, streptococci and mycoplasmas).. .
Immunogenic compositions for streptococcus pyogenes
The invention includes a gas antigen, gas 40, which is particularly suitable for use either alone or in combinations with additional gas antigens, such as gas 117, gas 130, gas 277, gas 236, gas 40, gas 389, gas 504, gas 509, gas 366, gas 159, gas 217, gas 309, gas 372, gas 039, gas 042, gas 058, gas 290, gas 511, gas 533, gas 527, gas 294, gas 253, gas 529, gas 045, gas 095, gas 193, gas 137, gas 084, gas 384, gas 202, and gas 057.. .
Multicomponent immunogenic composition for the prevention of beta-hemolytic streptococcal (bhs) disease
A number of β-hemolytic streptococci polynucleotides and polypeptides, particularly streptococcus pyogenes polypeptides and polynucleotides, are described. Two or more of the polypeptides of the invention can be formulated for use as immunogenic compositions.
Bacterium-based microrobot capable of targeting cancer tissue
To provide a bacterium-based microrobot which can be specifically targeted to cancer in vivo, the present invention provides a drug delivery system for cancer tissue, comprising a bacterium, and a microbead encapsulated with at least one drug, wherein biotin is bound to a surface of the bacterium and a surface of the microbead is coated with streptavidin.. .
Antifungal composition comprising polycyclic peptide compound and method for preparing the same
Disclosed are a novel strain with antibacterial activity, identified as streptomyces sp. An1542 strain (accession no.: kctc 12113bp), an antibacterial composition comprising a compound represented by chemical formula 1 or 2, or a strain producing the same as an active ingredient, and a method for producing the same.
Probiotic composition
Disclosed herein are probiotic compositions comprising a mixture of at least two probiotic bacteria, including streptococcus salivarius k12® (blis k12®) and at least a lactobacillus bacteria. The streptococcus salivarius k12® (blis k12®) may comprise streptococcus salivarius k12® (blis k12®) baa1024.
3-amino-2-hydroxy-4-phenylbutanoyl-valyl-isoleucine, preparation and use thereof
The compound is prepared from fermentation culture streptomyces parvus cgmcc no. 4027 and is active as inhibitor of aminopeptidase.
Small streptococcus pyogenes antigens and their use
The present invention relates to a peptide consisting of one antigen of streptococcus pyogenes (s. Pyogenes) of any of the seq id nos: 1 to 7 or a functional active variant thereof, optionally further consisting of additional amino acid residue(s); a nucleic acid coding for the same; a pharmaceutical composition, especially a vaccine, comprising said peptide or said nucleic acid; an antibody or functional active fragment thereof specifically binding to the antigen; a hybridoma cell line which produces said antibody; a method for producing said antibody; a pharmaceutical composition comprising said antibody; the use of said peptide or said nucleic acid for the manufacture of a medicament for the immunization or treatment of a subject; the use of said antibody or functional fragment thereof for the manufacture of a medicament for the treatment of an infection; a method of diagnosing a s.
Pesticidal mixtures
The present invention relates to a pesticidal mixture comprising, as active i) at least one active compound i selected from the group consisting of the streptomyces galbus strain having accession number nrrl 30232, the streptomyces galbus strain having accession number nrrl 50334, a mutant of said strains, a variant of said strains, a metabolite produced by said strains, a supernatant obtained from the whole broth culture of said strains and a solvent extract of said supernatants, wherein said mutant and variant have the identifying characteristics substantially identical to those of said strains, and 2) at least one active compound ii selected from the groups a.i to a.27 as defined in the description, in synergistically effective amounts. .
Uk-2 biosynthetic gene and method for improving uk-2 productivity using the same
The genomic dna of streptoverticillium sp. 3-7, which produces uk-2, was analyzed to identify a region expected to be a uk-2 biosynthetic gene cluster.
Fermentation processes for cultivating streptococci and purification processes for obtaining cps therefrom
This invention is in the field of bacterial cultures and specifically relates to the optimization of culture conditions to improve the production of bacterial capsular polysaccharides from streptococcus strains in fed batch culture and to novel purification methods suitable for production scale purification of bacterial capsular polysaccharides from streptococcus strains resulting in higher levels of purity than previously obtained for production scale.. .
Attenuated streptococcus suis vaccines and methods of making and use thereof
The present invention provides attenuated s. Suis strains that elicit an immune response in animal s.
Group b streptococcus vaccine
This application relates to improved group b streptococcus (“gbs”) saccharide-based vaccines comprising combinations of gbs polysaccharides with polypeptide antigens, and vice versa, such that the polypeptide and the saccharide each contribute to the immunological response in a recipient. The combination is particularly advantageous where the saccharide and polypeptide are from different gbs serotypes.
Modulators of gtpase and use in relevant treatment
The present invention relates to molecules which function as selective modulators of the ras-homologous (rho) family of small gtpases, in particular, cdc42 gtpase and their use to treat diseases, for example cancers, including metastatic cancer, genetic and acquired diseases where activation of cdc42 gtpase plays a pivotal role, such as neurodegenerative diseases, rheumatoid arthritis, atherosclerosis, diabetes type i, autosomal polycystic kidney disease, cystic kidney disease, precystic kidney disease, microbial infections, including chlamydia infections, e. Coli infections, h.
Methods of capturing bindable targets from liquids
A bindable target such as a bacterial cell, virus, or molecule is captured from a liquid by contacting the liquid with magnetically attractable particles have an affinity for the target, and causing said particles to move repeatedly through said liquid to at least one solid support zone by attractive magnetic forces to capture the target onto said particles. The particles may be ferromagnetic, paramagnetic or superparamagnetic particles and may bear antibody, antibody binding fragments, a substance having an epitope capable of reacting in a specific manner with an antibody, an aptamer, a nucleic acid sequence or a nucleic acid analogue sequence, biotin, avidin or streptavidin.
Oral health improving compositions
The present invention is concerned with microorganisms or fragments thereof as sensorically neutral oral care agents, particularly for prevention of dental calculus, as anti-caries agents and/or anti-oral malodor agents. The invention is furthermore concerned with compositions comprising microorganisms or fragments thereof for reducing mutans streptococci.
New animal model for diabetic complications
The invention relates to the surprising find that low density lipoprotein receptor-deficient mice (ldlr−/−) mice when fed with high energy diets produce controllable and consistent diabetic complications, especially renal damage, similar to the human pathophysiology and biological response. The invention thus comprises a method for discovering a preventive or therapeutic regimen for the prevention or treatment of diabetic micro- or macrovascular complications, comprising the steps of: a.
Marine streptomyces, pyranosesquiterpene compound, as well as preparation method and applications thereof
The invention discloses marine streptomyces sp., a pyranosesquiterpene compound, as well as a preparation method and uses thereof. Streptomyces sp.
Pneumococcal serotypes
Disclosed is a new and emerging serotype of streptococcus pneumoniae designated serotype 6c, and assays and monoclonal antibodies useful in identifying same. Also disclosed is a novel pneumococcal polysaccharide with the repeating unit {2) glucose 1 (1→3) glucose 2 (1→3) rhamnose (1→3) ribitol (5→phosphate}.
Vaccine composition against streptococcus pyogenes infection
The present invention relates to a vaccine composition against streptococcus pyogenes infection comprising an amino acid sequence having c-terminal fragment of streptococcal pyrogenic exotoxin b, and a pharmaceutical acceptable adjuvant.. .
Crystalline form of r)-3-(4-(2-(2-methyltetrazol-5-yl)pyridin- 5-yl)-3-fluorophenyl)-5-hydroxymethyl oxazolidin-2-one dihydrogen phosphate
A crystalline form of crystalline (r)-3-(4-(2-(2-methyltetrazol-5-yl)pyridin-5-yl)-3-fluorophenyl)-5-hydroxymethyl oxazolidin-2-one dihydrogen phosphate, methods of making the crystalline form and pharmaceutical compositions comprising the crystalline form are useful antibiotics. Further, the derivatives of the present invention may exert potent antibacterial activity versus various human and animal pathogens, including gram-positive bacteria such as staphylococi, enterococci and streptococi, anaerobic microorganisms such as bacteroides and clostridia, and acid-resistant microorganisms such as mycobacterium tuberculosis and mycobacterium avium.
Method for preparing fermentation broth of fruits and vegetables
A method for preparing fermentation broth of fruits and vegetables includes steps of mixing fruits, vegetables, bacteria liquid of lactobacillus acidophilus, bacteria liquid of bifidobactreium longum, bacteria liquid of lactobacillus delbrueckii subsp. Bulgaricus, and bacteria liquid of streptococcus thermophilus, and processing fermentation to obtain the fermentation broth of fruits and vegetables.
Agent for inducing interferon production containing lactic acid bacteria
This invention provides an ifn inducer comprising, as an active ingredient, lactic acid bacteria and capable of inducing ifn production, an immunopotentiating agent or prophylactic agent against virus infection comprising such inducer, and a food or drink product comprising such ifn inducer and having ifn-inducing activity, immunopotentiating activity, or prophylactic activity against virus infection. The agent for inducing ifn production comprises, as active ingredients, lactic acid bacteria that can activate plasmacytoid dendritic cells (pdcs) and promote ifn production, such as lactococcus garvieae nbrc100934, lactococcus lactis subsp.
Method for preparing pharmaceutical composition for enhancing immunity and pharmaceutical composition prepared according to the method
A method for preparing a pharmaceutical composition for enhancing immunity and a pharmaceutical composition prepared according to the method. The method includes steps of: mixing ginseng ethanol extract with fruit and vegetable fermentation conversion solution to obtain a mixture, namely, the pharmaceutical composition for enhancing immunity; wherein the ginseng ethanol extract is prepared by a following step of: reflux extracting ginseng by ethanol aqueous solution for obtaining the extract, namely, the ginseng ethanol extract; the fruit and vegetable fermentation conversion solution is prepared by following steps of: mixing fruit and vegetable, lactobacillus acidophilus bacteria solution, bifidobactreium longum bacteria solution, lactobacillus delbrueckiisubsp.
Bacteriophage lysin and antibiotic combinations against gram positive bacteria
The present invention provides compositions and methods for prevention, amelioration and treatment of gram positive bacteria, particularly staphylococcal bacteria, with combinations of lysin, particularly streptococcal lysin, particularly the lysin plyss2, and one or more antibiotic, including daptomycin, vancomycin, oxacillin, linezolid, or related antibiotic(s).. .
Treatment and prophylaxis for obsessive compulsive disorder
An embodiment is a method of preventing, mitigating or treating pediatric autoimmune neuropsychiatric disorders associated with streptococcal infections (pandas) that includes administering an effective amount of a medicament comprised of streptococcus oralis 89a to a human to prevent, mitigate or treat pandas.. .

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Strep topics: Streptococcus, Daptomycin, Antibiotic, Immunogenic, Nucleic Acid, Streptomyces, Pathogenic, Probiotics, Lactobacillus, Chromatograph, Antibiotics, Therapeutical, Chromatography, Solubility, Amino Acid

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This listing is a sample listing of patents related to Strep for is only meant as a recent sample of applications filed, not a comprehensive history. There may be associated servicemarks and trademarks related to these patents. Please check with patent attorney if you need further assistance or plan to use for business purposes. This patent data is also published to the public by the USPTO and available for free on their website. Note that there may be alternative spellings for Strep with additional patents listed. Browse our RSS directory or Search for other possible listings.

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