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Steoporosis

Steoporosis-related patent applications - as published by the U.S. Patent and Trademark Office (USPTO).


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Analogs of proxisome proliferator activated receptor (ppar) agonists and methods of using the same
The University Of Toledo
January 11, 2018 - N°20180012002

Peroxisome proliferator activated receptor (ppar) compounds, and methods of using the same for treating bone fractures, treating osteoporosis and/or metabolic bone diseases, and inducing osteogenesis and/or chondrogenesis, are disclosed.
Novel forms of [r-(r*,r*)]-2-(4-fluorophenyl)-beta, gamma-dihydroxy-5-(1-methylethyl)-3-phenyl-4...
Warner-lambert Company Llc
January 11, 2018 - N°20180009748

Novel forms of [r-(r*,r*)]-2-(4-fluorophenyl)-β,δ-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1h-pyrrole-1-heptatonic acid hemi calcium salt designated form xx, form xxi, form xxii, form xxiii, form xxiv, form xxv, form xxvi, form xxvii, form xxviii, form xxix, and form xxx, characterized by their x-ray powder diffraction, solid-state ...
Formulation for the prevention and treatment of bone related disorders
Council Of Scientific & Industrial Research
January 04, 2018 - N°20180000776

The present invention relates to a formulation of spinacea oleracea useful for the prevention or treatment of osteo-health related disorders. The present invention relates to the field of pharmaceutical formulation that provides extract, fractions, pure compound isolated from natural sources and formulation thereof useful for the prevention and treatment of various medical indications. Further, this invention relates to conditions associated ...
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Method for preventing and/or treating osteoporosis by using streptococcus thermophilus tci633 strain and its ...
Tci Co., Ltd
December 21, 2017 - N°20170360851

A method for at least one of preventing osteoporosis, treating osteoporosis, delaying bone loss, increasing bone density, and strengthening bones is provided, wherein the method comprises administering to a subject in need an effective amount of streptococcus thermophilus tci633 strain and/or its metabolites. The streptococcus thermophilus tci633 strain was deposited at german collection of microorganisms and cell cultures (deutsche ...
Fibronectin based scaffold domain proteins that bind to myostatin
Bristol-myers Squibb Company
December 14, 2017 - N°20170354718

The present invention relates to fibronectin-based scaffold domain proteins that bind to myostatin. The invention also relates to the use of these proteins in therapeutic applications to treat muscular dystrophy, cachexia, sarcopenia, osteoarthritis, osteoporosis, diabetes, obesity, copd, chronic kidney disease, heart failure, myocardial infarction, and fibrosis. The invention further relates to cells comprising such proteins, polynucleotides encoding such proteins or ...
Method of treating or preventing osteoporosis
Research Foundation Of The City University Of New York
December 14, 2017 - N°20170354617

A method for treating or preventing osteoporosis is provided that treats a patient with methylene blue.
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Biaryl derivative as gpr120 agonist
Lg Chem, Ltd.
December 07, 2017 - N°20170349594

The present invention relates to a biaryl derivative expressed by the chemical formula 1, a method for producing the biaryl derivative, a pharmaceutical composition comprising same, and use of same, the biaryl derivative expressed by the chemical formula 1, as a gpr120 agonist, promoting glp-1 generation in the gastro-intestinal tract, reducing insulin resistance in the liver, muscles and the like from anti-inflammatory ...
N-(4-hydroxy-4-methyl-cyclohexyl)-4-phenyl-benzenesulfonamide and n-(4-hydroxy-4-methyl-cyclohexyl)-4-(2-pyridyl)-benzenesulfonamide compounds and ...
Pimco 2664 Limited
December 07, 2017 - N°20170349551

The present invention pertains generally to the field of therapeutic compounds. More specifically the present invention pertains to certain substituted n-(4-hydroxy-4-methyl-cyclohexyl)-4-phenyl-benzenesulfonamide and n-(4-hydroxy-4-methyl-cyclohexyl)-4-(2-pyridyl)benzenesulfonamide compounds (collectively referred to herein as hmc compounds) that are useful, for example, in the treatment of disorders (e. G., diseases) including, inflammation and/or joint destruction ...
Si-o-n-p related fabrication methods, surface treatments and uses thereof
The Texas A&m University System
December 07, 2017 - N°20170348459

Disclosed are compositions, methods and processes for fabricating and using a device or other implement including a surface or surfaces having a nanoscale or microscale layer or coating of si—o—n—p. These coatings and/or layers may be continuous, on the surface or discontinuous (e. G., patterned, grooved), and may be provided on silica surfaces, ...
Calcifediol soft capsules
Faes Farma, S.a.
December 07, 2017 - N°20170348249

The present invention relates to calcifediol soft capsules, to their use in the treatment or prevention of diseases related to vitamin d deficiency, such as vitamin d deficiency, demineralization such as hypocalcemia and hypophosphatemia, renal osteodystrophy, rickets, osteoporosis, osteopenia, osteoarthritis, osteoarthrosis, osteomalacia, hypoparathyroidism, and inflammatory bowel disease, and to their process of manufacture.
Use of microrna precursors as drugs for inducing cd34-positive adult stem cell expansion
November 30, 2017 - N°20170342418

This invention generally relates to a composition and its production method useful for developing drugs/vaccines and/or therapies against a variety of degenerative diseases in humans. Particularly, the present invention teaches the essential steps of production and purification processes necessary for producing small hairpin-like rna (shrna) compositions, such as microrna precursors (pre-mirna) and short interfering rnas (sirna), which are ...
Protease inhibitors
November 23, 2017 - N°20170334867

Or a pharmaceutically acceptable salt, n-oxide or hydrate thereof, have utility in the treatment of disorders characterized by inappropriate expression or activation of cathepsin k, such as osteoporosis, osteoarthritis, rheumatoid arthritis or bone metastases.
Expression and function of gpr64/adgrg2 in endocrine systems and methods to target it therapeutically
November 23, 2017 - N°20170333522

Provided herein are methods of treating hypercalcemia in a subject, comprising administering to the subject a therapeutically effective amount of a composition that decreases the expression level and/or activity of gpr64. Compositions comprising the therapeutic agents and methods of screening for agonists and inhibitors of gpr64 are also provided. Compositions and methods for treating primary hyperparathyroidism, secondary hyperparathyroidism, hypoparathyroidism, ...
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Metal bisphosphonate nanoparticles for anti-cancer therapy and imaging and for treating bone disorders
The University Of North Carolina At Chapel Hill
November 23, 2017 - N°20170333347

Metal-bisphosphonate nanoparticles are disclosed. Also disclosed are pharmaceutical compositions including the metal-bisphosphonate nanoparticles, methods of preparing the metal-bisphosphonate nanoparticles and materials comprising the nanoparticles, and methods of using the compositions to treat cancer or bone-related disorders (e. G., bone-resorption-related diseases, osteoporosis, paget's disease, and bone metastases) and as imaging agents.
Method to prevent cancer metastasis to bone
Lexi Pharma Inc.
November 16, 2017 - N°20170326130

A method for treating osteoporosis and related methods are disclosed. The methods generally comprise administering to a patient in need of treatment an effective amount of tris(8-quinolinolato)gallium(iii) or an analog thereof.
New molecules for bone tissue regeneration
Universita' Di Pisa
November 09, 2017 - N°20170319605

The invention relates to compounds of general formula (i) and pharmaceutically acceptable salts thereof: (i) wherein ri is selected from an scn— group or is an rconh— group; in particular, where ri=rconh, r is selected from an aromatic benzene ring substituted with an scn— group in the ortho, meta or para position, according to the following ...
Combination of lupeol acetate and curcumin used for the treatment or prevention of osteoporosis
November 02, 2017 - N°20170312294

The present invention relates to synergistic combinations of lupeol acetate and curcumin at low dosage, and their use for the treatment or prevention of osteoporosis.
Methods for treatment of disease using galvanic vestibular stimulation
The Regents Of The University Of California
October 26, 2017 - N°20170304616

Methods are provided for treating diseases by altering body mass composition in a human subject through application of galvanic vestibular stimulation (gvs) using electrodes placed in electrical contact with the subject's scalp at a location corresponding to each of the subject's left and right vestibular systems. The methods may be used to treat obesity-related diseases such as diabetes, hypertension, type 2 ...
Treatment of male androgen deficiency symptoms or diseases with sex steroid precursor combined with serm
Endorecherche, Inc.
October 12, 2017 - N°20170290847

Novel methods for prevention, reduction or elimination of the incidence of male androgen deficiency symptoms or diseases including male hypogonadism-associated symptoms and diseases associated with low serum testosterone and/or low dhea or low total androgens in susceptible warm-blooded animals including humans involving administration of an amount of a sex steroid precursor, particularly dehydroepiandrosterone (dhea) and a selective estrogen receptor ...
Compounds and methods for kinase modulation, and indications therefor
October 05, 2017 - N°20170283423

In certain aspects and embodiments, the described compounds or salts thereof, formulations thereof, conjugates thereof, derivatives thereof, forms thereof are active on one or more of fms, kit, flt3, trka, trkb and trkc kinase protein. Also described are methods of use thereof to treat diseases and conditions, including diseases and conditions associated with activity of one or more of fms, ...
Proxisome proliferator activated receptor (ppar) compounds and methods of using the same
The University Of Toledo
October 05, 2017 - N°20170283385

Peroxisome proliferator activated receptor (ppar) compounds, and methods of using the same for treating bone fractures, treating osteoporosis and/or metabolic bone diseases, and inducing osteogenesis and/or chondrogenesis, are disclosed.
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