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Stem Cells

Stem Cells-related patent applications - as published by the U.S. Patent and Trademark Office (USPTO).


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NEW Methods for assessing the purity of a mesenchymal stem cells preparation
Novadip Biosciences Sa
May 17, 2018 - N°20180135124

The present invention relates to a method for assessing, evaluating and/monitoring the purity of a mesenchymal stem cells preparation, in particular of an adipose stem cells preparation, comprising measuring the expression level of at least one growth factor.
NEW Duck embryonic derived stem cell lines for the production of viral vaccines
Valneva
May 17, 2018 - N°20180135026

The present invention relates to the development and manufacturing of viral vaccines. In particular, the invention relates to the field of industrial production of viral vectors and vaccines, more in particular to the use of avian embryonic stem cells, preferably the ebx® cell line derived from duck embryonic stem cells, for the production of viral vectors and viruses. The ...
NEW Induction of hepatocytes by stem cell differentiation with rna
Allele Biotechnology And Pharmaceuticals, Inc.
May 17, 2018 - N°20180135023

A novel method of inducing or producing hepatocytes from human induced pluripotent stem cells at an unprecedented efficiency and functionality. The core of the invention is the use of experimentally discovered mrnas at multiple critical differentiation decision points along a pluripotent to mesendoderm to endoderm to hepatocytes pathway in a previously unknown manner.
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NEW Induction of pancreatic beta cells by stem cell differentiation with rna
Allele Biotechnology And Pharmaceuticals, Inc.
May 17, 2018 - N°20180135021

A novel method of inducing or producing pancreatic beta cells from human induced pluripotent stem cells at an unprecedented efficiency and functionality. The core of the invention is the use of experimentally discovered mrnas at multiple critical differentiation decision points along a pluripotent to mesendoderm to endoderm to pancreatic endocrine cells to pancreatic beta cells pathway in a previously unknown ...
NEW Methods and products for enriching and isolating stem cells
Adelaide Research & Innovation Pty Ltd
May 17, 2018 - N°20180135019

The present disclosure relates to methods and products for enriching and isolating stromal stem cells. Certain embodiments of the present disclosure provide a method of enriching for immature, uncommitted stromal stem cells from a population of cells comprising stromal stem cells, the method comprising enriching stromal stem cells from the population of cells using a hsc70 binding agent.
NEW Composition and method of stem cells for preservation of cardiac tissue
May 17, 2018 - N°20180135017

The method and composition may be used in medicine or cosmetic application, in particular, in treatment of cardiac tissue and/or cardiac diseases, and/or in the treatment of wound healing namely diabetic wound healing
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NEW Analogues of vdac1-derlved peptides
The National Institute For Biotechnology In The Negev Ltd.
May 17, 2018 - N°20180134760

The present invention relates to peptides comprising analogues of vdac1-derived peptides having improved pharmacokinetic characteristics compared to the native parent peptides, which are effective in impairing cell energy production, in inducing apoptosis and cell death, particularly of cancerous cells, in eliminating cancer stem cells and in reducing symptoms associated with fat accumulation in liver cells particularly with nonalcoholic fatty ...
NEW Peptide and its derivatives capable of inhibiting replication of hepatitis c virus in human adipose-derived ...
Inno Bio-drug Development Limited
May 17, 2018 - N°20180134751

The present invention provides a peptide with sequence of deaqetavssheqd, a fragment of rabbit-α1 antiproteinase f, and its derivatives deaqetavssheq and qetacssheqd, which significantly inhibit serum-borne hcv replication in hadsc and human hepatocytes.
NEW Materials and methods for tissue regeneration
Georgia Tech Research Corporation
May 17, 2018 - N°20180133364

The invention provides materials presenting a biologically active matrix comprising a physiological fibrillar fibronectin network, such as implantable constructs, and their use for modulating cell behaviour and fate, including cell growth, proliferation and/or differentiation, such as for promoting tissue regeneration, for example, bone regeneration or vascularization. Also provided are constructs presenting a biologically active matrix comprising a physiological fibrillar ...
NEW Treatment of pain using placental stem cells
Anthrogenesis Corporation
May 17, 2018 - N°20180133261

Provided herein are methods of treatment of an individual having pain, e. G., neuropathic pain, comprising administering to the individual a therapeutically effective amount of tissue culture plastic adherent placental stem cells (pdac™).
NEW Method for enhancing insulin like growth factor 1 receptor expression of mesenchymal stem cell, method for ...
China Medical University
May 17, 2018 - N°20180133259

A method for enhancing an insulin like growth factor 1 receptor expression of a mesenchymal stem cell is provided. The method includes culturing a plurality of mesenchymal stem cells expressing insulin-like growth factor 1 receptors in media containing human cord blood serum to enhance the insulin like growth factor 1 receptor expression of the mesenchymal stem cells.
NEW Treatment of cachexia using stem cells and products thereof
Creative Medical Health, Llc
May 17, 2018 - N°20180133258

The current invention teaches the use of cells possessing regenerative properties, tissues associated with said cells possessing regenerative properties, and products derived from cells possessing regenerative properties for the treatment of cachexia. In one embodiment, cancer or hiv associated cachexia is treated by administration of tissues possessing regenerative cells that have been modified to allow for administration in a manner ...
Method of screening an agent for inhibiting recurrence or metastasis of breast cancer
Gil Medical Center
May 10, 2018 - N°20180128815

The present invention relates to a method of screening preparations for inhibiting metastasis or recurrence of breast cancer using the change in the expression level of marker genes for breast cancer stem cells, wherein their expression levels are changed by the treatment with a wnt signaling inhibitor. The method of the present invention enables to screen preparations for preventing or ...
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  • 656+ full patent PDF documents of Stem Cells-related inventions.
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Production and therapeutic uses of epinul pluripotent cells and differentiated cells derived therefrom
Biomedistem, Llc
May 10, 2018 - N°20180127738

Compositions and methods are provided for the generation of highly potent conditioned stem (epinul) cells from adult somatic cells or tissues. Such conditioned stem cells are capable of generating all the cell lineages of any tissue or organ. Uses and compositions of the conditioned stem cells are also disclosed.
Method for producing myocardial cells using synthetic peptide
Kyoto University
May 10, 2018 - N°20180127727

Provided is a method for producing myocardial cells from pluripotent stem cells. The myocardial cell production method provided by the present invention includes supplying an artificially produced synthetic peptide to a cell culture that contains pluripotent stem cells. The synthetic peptide is a peptide that contains a myocardial cell differentiation-inducing peptide sequence that induces pluripotent stem cells into myocardial cells. ...
Protein-induced pluripotent cell technology and uses thereof
Wayne State University
May 10, 2018 - N°20180127725

A method of generating protein-induced pluripotent stem cells by delivering bacterial! Y expressed reprogramming proteins into nuclei of starting somatic cells using the qq-protein transduction technique, repeating several cell reprogramming cycles for creating reprogrammed protein-induced pluripotent stem cells, moving the reprogrammed cells into a feeder-free medium for expansion, and expanding and passaging the reprogrammed cells in a whole dish for ...
Method of isolating mesenchymal stem cells from the amniotic membrane of the umbilical cord, a ...
Cellresearch Corporation Pte. Ltd.
May 10, 2018 - N°20180127721

The present invention relates to a method of isolating a mesenchymal stem cell population from the amniotic membrane of the umbilical cord, the method comprising cultivating umbilical cord tissue in a culture medium comprising dmem (dulbecco's modified eagle medium), f12 (ham's f12 medium), m171 (medium 171) and fbs (fetal bovine serum). The invention also relates to a mesenchymal stem population isolated ...
Maintenance and propagation of mesenchymal stem cells
The United States Of America As Represented By The Department Of Veterans Affairs
May 10, 2018 - N°20180127720

Various embodiments of the present invention include compositions, materials and methods for maintaining and propagating mammalian mesenchymal stem cells in an undifferentiated state in the absence of feeder cells and applications of the same.
Method for differentiating pluripotent stem cells into desired cell type
Keio University
May 10, 2018 - N°20180127714

Provided is a method of differentiating a pluripotent stem cell of mammalian origin into a desired cell type by predicting the direction of cell differentiation to be caused by induction of expression of a transcription factor. A human gene expression correlation matrix using human cells has been newly created, and further, it has been confirmed that human pluripotent stem cells ...
Method of producing stem cell-derived endothelial cells and uses thereof
Industry-academic Cooperation Foundation, Yonsei University
May 10, 2018 - N°20180127713

This disclosure relates to methods of generating endothelial cells derived from stem cells. In certain embodiments, the cells are useful for inducing vasculature in muscles and cardiac tissue. In certain embodiments, the disclosure relates to methods of transforming pluripotent or multipotent stem cells, such as embryonic or induced pluripotent stem cells, into endothelial cells derived therefrom using a gsk3 inhibitor ...
Methods of enhancing cell survival of stem cells
The Scripps Research Institute
May 10, 2018 - N°20180127712

The present invention relates compounds for stabilizing cells and methods of their use.
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