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Stem Cells

Stem Cells-related patent applications - as published by the U.S. Patent and Trademark Office (USPTO).


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Projected capacitive multi electrode eukaryotic cell array
Stemonix Inc.
November 09, 2017 - N°20170322194

The present subject matter discloses various exemplary projective capacitive micro structured electrode arrays for measuring the impedance and action potential of living cells in particular induced pluripotent stem cells that are subsequently differentiated into cardiomyocytes and neurons. In one exemplary system a projective capacitive electrode array with cardiomyocytes attached onto the electrodes is formed and electrical measurements of live cell ...
Methods of generating retinal progenitor cell preparations and uses thereof
The Research Foundation For The State University Of New York
November 09, 2017 - N°20170321188

The present invention relates to methods of generating preparations of neural progenitor cells and retinal progenitor cells from populations of stem cells. These methods involve the administration of tbx3 alone or in combination with pax6. The preparations of neural and retinal progenitor cells prepared in accordance with the methods disclosed herein are suitable for use in methods of treating individuals ...
Methods for manipulating phagocytosis mediated by cd47
The Board Of Trustees Of The Leland Stanford Junior University
November 09, 2017 - N°20170320945

Methods are provided to manipulate phagocytosis of cells, including hematopoietic cells, e. G. Circulating hematopoietic cells, bone marrow cells, acute leukemia cells, etc.; and solid tumor cells. In some embodiments of the invention the circulating cells are hematopoietic stem cells, or hematopoietic progenitor cells, particularly in a transplantation context, where protection from phagocytosis is desirable. In other embodiments the circulating ...
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Method for manufacturing ciliary margin stem cells
Riken
November 09, 2017 - N°20170319748

The invention provides a method for producing a ciliary marginal zone stem cell induced to differentiate from a pluripotent stem cell, including either the following step (1) or step (2), or both of these steps: (1) a step of floating culturing cells obtained from a cell aggregate containing a ciliary marginal zone-like structure induced to differentiate from pluripotent stem cells, thereby obtaining a ...
Porous polysaccharide scaffold comprising nano-hydroxyapatite and use for bone formation
Universite Paris Diderot - Paris 7
November 09, 2017 - N°20170319741

The present invention relate to three dimensional porous polysaccharide matrices able to induce mineralisation of a tissue in osseous site, as well as in non-osseous site, in the absence of stem cells or growth factors.
Stable neural stem cells comprising an exogenous polynucleotide coding for a growth factor and methods ...
Neuralstem, Inc.
November 09, 2017 - N°20170319625

The present disclosure provides a human neural stem cell comprising an exogenous polynucleotide coding for a growth factor such as igf-1. Also disclosed are methods of using the human neural stem cells for the treatment of neurodegenerative diseases or disorders including, for example, als.
Stem Cells Patent Pack
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Stem Cells Patent Applications
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inventor
  • 656+ full patent PDF documents of Stem Cells-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
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Novel methods for targeting cancer stem cells
Boston Biomedical, Inc.
November 09, 2017 - N°20170319537

The invention provides naphthofuran compounds, polymorphs of naphthofuran compounds, naphthofuran compounds in particle form, purified compositions that contain one or more naphthofuran compounds, purified compositions that contain one or more naphthofuran compounds in particle form, methods of producing these naphthofuran compounds, polymorphs, purified compositions and/or particle forms, and methods of using these naphthofuran compounds, polymorphs, purified compositions and/or ...
Hair growth-promoting composition
Boston Biomedical, Inc.
November 09, 2017 - N°20170319468

Provided is a hair growth-promoting composition comprising: 100 parts by weight of a stem cell culture solution obtained from a culture medium of mesenchymal stem cells which have been subcultured two or more times; 0. 001 to 0. 1 parts by weight of zinc; 5 to 50 parts by weight of a panthenol based compound; and 0. 0001 to 0. 1 parts by weight of a water-soluble vitamin, wherein it is ...
Inhibition and enhancement of reprogramming by chromatin modifying enzymes
Boston Biomedical, Inc.
November 02, 2017 - N°20170313989

In one aspect, the disclosure provides methods and compositions for the production of stem cells. In one aspect, the disclosure provides methods and uses of stem cells. In some embodiments, the stem cells are induced pluripotent stem cells.
Methods and agents for cellualr reprogramming
Boston Biomedical, Inc.
November 02, 2017 - N°20170313988

The present invention relates to a new transcript referred to here as int6-5a, which is an isoform of the human transcript, known in the literature, int6 full length (int6-fl) encoded by the gene eif3e (gene id 3646, mrna nm_001568. 2), the use thereof in cellular reprogramming methods for the production of induced pluripotent stem cells or somatic stem ...
Method of manufacturing pancreas islet of langerhans mimics using induced pluripotent human stem cells
Boston Biomedical, Inc.
November 02, 2017 - N°20170313987

The present disclosure provides a method of manufacturing pancreas islet of langerhans (iol) mimetics using induced human pluripotent stem cells (ipsc) and porous micro carrier scaffolds that allow for subsequent vascularization and/or innervation.
Medium composition for culturing stem cells
Boston Biomedical, Inc.
November 02, 2017 - N°20170313986

According to the present disclosure, it is capable of improving proliferation ability and differentiation ability of the mesenchymal stem cells, and is capable of producing cell therapy products more economically using the mesenchymal stem cells by enabling the mesenchymal stem cells to be cultured at a low price compared to the existing culturing methods.
Culture media for multipotent stem cells
Boston Biomedical, Inc.
November 02, 2017 - N°20170313985

A culture medium for human adipose tissue derived mesenchymal stem cells includes a keratinocyte-sfm basal medium, l-cysteine, fgf and sdf-1 is disclosed. The culture medium is effective for growing mesenchymal stem cells at a high proliferation rate while maintaining the purity, characterization and undifferentiated state of the cells.
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Stem Cells Patent Applications
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inventor
  • 656+ full patent PDF documents of Stem Cells-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
Endogenous retrovirus transcription as a marker for primate naive pluripotent stem cells
Boston Biomedical, Inc.
November 02, 2017 - N°20170313978

One or more type 7 long terminal repeat (ltr7) nucleic acid sequences of type h human endogenous retroviruses (hervh) (“ltr7/hervh nucleic acid sequences”) can be used for identifying primate naïve pluripotent stem cells. Ltr7/hervh-associated transcription can be used as a marker for primate naive pluripotent stem cells. A reporter construct that includes ltr7/...
Antibodies that specifically bind to tim3
Boston Biomedical, Inc.
November 02, 2017 - N°20170313783

Provided herein are antibodies specific for tim3 that can be used to detect cancer cells, in particular, cancer stem cells. The antibodies can also be used in therapeutic compositions for treating cancer and reducing inflammation.
Multi-dimensional biomaterial and method for producing the same
Boston Biomedical, Inc.
November 02, 2017 - N°20170312390

Biomaterial having a multi-dimensional structure and comprising demineralized bone matrix dispersed within differentiated mesenchymal stem cells (mscs) tissue, wherein mscs are adipose tissue-derived stem cells. Method for producing this biomaterial comprising incubating mscs in osteoblastic and/or chondrongenic medium in presence of demineralized bone matrix. Use of this biomaterial for alleviating or treating a bone or cartilage defect, supporting or ...
Composition for treating cancer stem cells
Boston Biomedical, Inc.
November 02, 2017 - N°20170312333

The present invention relates to a composition for effectively treating cancer stem cells, and more specifically to a composition for treating cancer stem cells, which contains a glucose uptake inhibitor, a biguanide-based compound, and a calcium pump inhibitor. The composition of the present invention can be used as an agent of treating cancer stem cells by effectively inducing apoptosis of ...
Platform and methods for analyzing effects of genetics, age and environment in stimulus-response studies using ...
Coyne Ip Holdings, Llc
October 26, 2017 - N°20170307597

Platforms and methods for conducting stimulus-response studies on induced pluripotent stem cells, or cells differentiated therefrom, that have been derived from cells collected from donors. Samples are taken at various ages and/or before and after exposure to environmental conditions. Methods for preparing the platforms are also provided. In one embodiment, multiple donors are involved. In another embodiment, induced pluripotent ...
Methods for conducting stimulus-response studies with induced pluripotent stem cells derived from perinatal cells or ...
Coyne Ip Holdings, Llc
October 26, 2017 - N°20170307596

Methods are provided herein for conducting stimulus-response studies on ipscs, or cells derived from ipscs, that have been derived from perinatal cells collected from donors under null-exposome conditions. In some embodiments, multiple donors are involved. In other embodiments, the ipscs are differentiated. The use of induced pluripotent stem cells (ipscs) derived from cells that originate from neonates enable a scientist ...
Engineering a heterogeneous tissue from pluripotent stem cells
Massachusetts Institute Of Technology
October 26, 2017 - N°20170306351

Aspects of the present disclosure are directed to methods and compositions for the production of heterogeneous tissue from human induced pluripotent stem (hips) cells.
Artificial three-dimensional microenvironment niche culture and methods of using the same
Dnamicroarray, Inc.
October 26, 2017 - N°20170306297

Described here are three-dimensional microenvironment niches prepared from biomaterial compositions that support growth and self renewal of stem cells. The invention also provides methods for inducing pluripotency in a somatic cell using chemical compounds, as well as methods for screening for compounds that can induce pluripotency in a somatic cell.
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