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Spore patents

      

This page is updated frequently with new Spore-related patent applications.




 Methods and  assays of bacterial spores patent thumbnailMethods and assays of bacterial spores
Described herein are methods and apparatus for assays of bacterial spores. In particular, methods and apparatus for lateral flow immunoassay for bacterial spore detection and quantification, live/dead assay for bacterial spores, lifetime-gated measurements of bacterial spores and imaging bacterial spores using an active pixel sensor, and unattended monitoring of bacterial spores in the air are described..
California Institute Of Technology


 Bacillus megaterium recombinant protein expression system patent thumbnailBacillus megaterium recombinant protein expression system
The present invention relates to isolated or purified asporogenous bacillus megaterium (b. Megaterium) strains comprising a b.
Merck Sharp & Dohme Corp.


 Isolated strain of clonostachys rosea for use as a biological control agent patent thumbnailIsolated strain of clonostachys rosea for use as a biological control agent
Described is an isolated strain of the fungus colonostachys rosea termed bvt cr-7 useful as a biological control agent for the treatment of plants. The isolated strain, formulations comprising said strain and/or spores derived from said strain may be applied to plants or plant materials in order to improve plant yield, to improve plant growth, or for the treatment or prevention of diseases or pathogens in the plant..
Bee Vectoring Technology Inc.


 Method and  sterilizing and disinfecting air and surfaces and protecting a zone from external microbial contamination patent thumbnailMethod and sterilizing and disinfecting air and surfaces and protecting a zone from external microbial contamination
This invention relates to a method, process and apparatus for disinfecting and sterilizing all types of surfaces contaminated with microorganisms and toxic substances to render both inactive. Furthermore, this invention relates to both a method and apparatus for disinfecting and/or sterilizing breathable air and then using this air to protect a confined space from external contamination.

 Engineered water nanostructures (ewns) and uses thereof patent thumbnailEngineered water nanostructures (ewns) and uses thereof
Various embodiments of the present invention relate to, among other things, systems for generating engineered water nanostructures (ewns) comprising reactive oxygen species (ros) and methods for inactivating at least one of viruses, bacteria, bacterial spores, and fungi in or on a wound of a subject in need thereof or on produce by applying ewns to the wound or to the produce.. .

 Composition essentially free of water and comprising at least one spore forming fungal biological control agent, a polyether-modified trisiloxane and fumed or precipitated silica patent thumbnailComposition essentially free of water and comprising at least one spore forming fungal biological control agent, a polyether-modified trisiloxane and fumed or precipitated silica
The present invention relates to a liquid composition comprising at least one biological control agent wherein said biological control agent is spores of a spore forming fungus, a polyether-modified trisiloxane and fumed silica or precipitated silica, wherein said composition is essentially free of water, said composition being useful in plant protection.. .

 Phenotypic engineering of spores patent thumbnailPhenotypic engineering of spores
The biological functionality of living microbial spores is modified using phenotypic engineering to endow the resulting modified spores with novel functionality that extends the usefulness of the spores for a variety of practical applications including, for example, sterility testing, the release of active compounds, and cell-based biosensing systems. An embodiment entails engineering bacillus spores to acquire synthetic new functions that enable the modified spores to sense and rapidly transduce specific germination signals in their surroundings.
Bcr Diagnostics, Inc.


 Nutrient rich germinant composition and spore incubation method patent thumbnailNutrient rich germinant composition and spore incubation method
A nutrient-germinant composition to aid in spore germination and a method for increased spore germination efficiency. The composition comprises l-amino acids, d-glucose and/or d-fructose, a phosphate buffer, an industrial preservative, and may include bacteria spores or they may be separately combined for germination.
Nch Corporation


 Immunomodulation using spores and pollen grains patent thumbnailImmunomodulation using spores and pollen grains
The present invention includes compositions, methods of making and using the compositions for modulating the immune response in a subject by providing a vaccine composition having a pollen or spore disposed in a pharmaceutical carrier for delivery to a subject, wherein the pollen or spore comprises multiple pores that connect an outer surface of the pollen/spore to an inner cavity and one or more antigens disposed on the outer surface, in the inner cavity, in the multiple pores, or a combination thereof, wherein the one or more antigens modulate an immune responses in the subject.. .
Texas Tech University System


 Compositions for photodynamic control of infection patent thumbnailCompositions for photodynamic control of infection
The present invention relates to compositions for the photodynamic control of micro-organisms wherein the compositions comprise a photosensitiser which comprises a dyestuff and produces singlet oxygen when irradiated by means of light for the disinfection and sterilization of materials, commodities and surfaces contaminated with one or more species of micro-organisms including bacteria, fungi, algae, yeasts, bacterial spores and fungal spores.. .
Purepurge, Inc.


Method and system of cultivating cordyceps

The present invention relates to a system and method of cultivating cordyceps, specifically, provided herein is a system of cultivating cordyceps comprising: a hepialus moth trapping device; a hepialus moth eggs screening device, wherein the device is connected with the hepialus moth trapping device; an ascospores-collecting device; a mycelia-preparing device; a conidia-preparing device; an infection device, wherein the device is connected with the ascospores-collecting device, the mycelia-preparing device and the conidia-preparing device; and a feeding device, wherein the device is connected with the hepialus moth eggs screening device and the infection device. And also provided is a method of using the system to cultivate cordyceps..
Yichang Shanchengshuidu Cordyceps Co., Ltd.

Method for preparing solid trichoderma seed from direct fermentation of crop straws with trichoderma, and product prepared by using the same

A method for preparing a solid trichoderma seed from direct fermentation of crop straws with trichoderma, and a product prepared by using the same. The method includes adding a liquid amino acid to the crop straws, adjusting the initial ph to 3.0-4.0, and inoculating a liquid trichoderma seed for solid fermentation.
Nanjing Agricultural University

Compositions for the restoration of a fecal microbiota and methods for making and using them

In alternative embodiments, the invention provides compositions and methods for treating various disorders and conditions in mammals, including chronic disorders in which there is a presence of an abnormal microbiota or an abnormal distribution of microflora in the gastrointestinal tract. In alternative embodiments, the invention provides liquid preparations or formulations derived from a human fecal material (e.g., a stool) processed, e.g., filtered and/or centrifuged, such that all bacteria, fungal spores and viruses are removed, but retaining the native biologically active molecules from the fecal material and bacteriophages.
Crestovo Llc

Sporicidal composition

A sporicidal composition includes an acidified short or medium chain, linear or branched alcohol having a ph effective to promote killing of spore forming bacteria and bacterial spores.. .
Case Western Reserve University

System and methods for detecting and remediating mold

The present disclosure relates to systems for detecting, treating, comparing and testing for mold, mold spores and mold fragments physically present or in the air of an environment. Methods for remediating the effects of mold are also described herein..

Method for prolonging the viability of fungal spores in liquid formulations

The present invention relates to a method for prolonging spore viability of fungal spores present in a liquid formulation, comprising (a) packaging said formulation in a suitable container; (b) reducing oxygen exposure of the spores in said formulation as compared to oxygen exposure of said spores when said formulation is in contact with air; and (c) closing or sealing said container. The invention further relates to a closed container comprising a liquid formulation within said container, said formulation comprising fungal spores, wherein the spores in said formulation have reduced oxygen exposure as compared to oxygen exposure of said spores when said formulation is in contact with air..
Bayer Cropscience Biologics Gmbh

Apparatus to control reaction of peroxide and alkaline

The present invention relates to an apparatus designed to control the application of the previously uncontrollable reaction of a peroxide composition and an alkaline composition, and accurately maintain the desired composition ratios for removal of and destruction of microbiological and organic contamination on a surface safely and without waste of the materials. The apparatus may also be used to maintain the highest demulsifying and antimicrobial activity of an organic acid composition blended with a peroxide composition by limiting contact time and the level of degradation of the components of the organic acid composition.

Ether amines for enhanced sporicidal performance

A composition and method are used to treat articles suspected of contamination with bacterial spores. The composition and method are effective against bacterial spores selected from c.
Ecolab Usa Inc.

System and process for destroying c. botulinum spores in pressed beverage using thermal pascalization

A system and process for destroying c. Botulinum spores in ready to drink beverages is presented.
Pressed Juicery, Llc

Conteneur oxo-biodegradable antimicrobien

An oxo-biodegradable antimicrobial receptacle for organic waste or waste from care activities which comprises a layer comprising low density polyethylene, an oxo-biodegradation additive at between 0.2 and 2.2% by weight and an antimicrobial additive at between 0.2 and 2.2% by weight, distributed in the polyethylene. It affords a period of preservation, in the dark, of at least 3 years, preferably 5 years, at a temperature not exceeding 30° c.
Cleanis

Nanostructured spore carrier

spore carriers suitable for use in biological indicators are described. The spore carriers include a substrate such as polymeric film or non-woven web with a hydrophilic nanostructured layer bonded to it.
3m Innovative Properties Company

Stable compositions of uncomplexed iodine and methods of use

The present invention is directed to a composition in solution (often, an aqueous solution) which comprises a combination of molecular iodine (i2) and an acceptable source of iodate (io3), and an acid (inorganic or organic), wherein iodide and iodate are present in the composition at a molar ratio of about 0.1 to about 25, the concentration of uncomplexed molecular iodine is a disinfectant, biocidal and/or antimicrobial (depending upon the end use of the composition) effective amount the concentration of acid in the composition is effective to provide a buffering ph in the composition ranging from about 1.5 to about 6.5. Compositions according to the present invention are storage stable for unexpectedly long periods of time (up to about 5 years), and find use as disinfecting solutions, as germicides and/or biocides (e.g.
Iotech International, Inc.

Hypochlorite based hard surface disinfectants

A disinfectant includes a source of chlorine, a buffer system, a ph adjuster, and a polar carrier. The disinfectant has a ph of 9.9-11 and activity against clostridium difficile spores and mycobacterium within a 3 minute kill time.
Metrex Research, Llc

Use of iron oxide nanoparticle in inhibiting spore germination of clostridium difficile

Disclosed herein is a use of fe3-δo4 nanoparticle in inhibiting the spore germination of clostridium difficile. The fe3-δo4 nanoparticle specifically targets the spores of clostridium difficile spores by damaging and breaking the intact structure of the clostridium difficile spores.

Compositions and methods

Disclosed herein are therapeutic compositions containing non-pathogenic, germination-competent bacterial spores, for the prevention, control, and treatment of gastrointestinal diseases, disorders and conditions and for general nutritional health.. .
Seres Therapeutics, Inc.

Distributed biological monitoring system

A system for the detection of biological markers over a distributed area is disclosed. The system utilizes a fleet of mobile platforms, which are pseudo randomly distributed over a geographic region.

Self-contained biological indicator

A scbi useful in ambient air pressure systems is disclosed. The scbi includes a body which serves as the culture tube, a glass media ampoule, an inoculated stainless steel disc positioned on the top of the glass media ampoule so that the spores are close to the top/opening of the scbi, filter paper on the top of the body and overlying the disc, and a cap..
Mesa Laboratories, Inc.

In situ biomass generator with automated disinfection

A self-contained biomass generator configured for use in growing and discharging bacteria at or near an intended use site and having a housing containing a bacteria growth chamber; water and air inlets; receptacles and solenoid pumps for liquids containing bacteria spores, nutrient, defoamer and disinfectant; a recirculation pump; air pump; water heater; manifold; a dosing pump configured to dispense controlled amounts of bacteria; and a programmable electronic controller configured to operate the device through a plurality of bacteria growth cycles and to disinfect the wetted internal surfaces between growth cycles without requiring service or operator intervention. A process for using the biomass generator is also disclosed..
Nch Corporation

Graft copolymer functionalized article

Guanidinyl ligand-functionalized polymers, methods of making the same, and substrates bearing a grafted coating of the ligand-functional polymers are described. The grafted polymer has the requisite affinity for binding neutral or negatively charged biomaterials, such as cells, cell debris, bacteria, spores, viruses, nucleic acids, endotoxins and proteins, at ph's near or below the pi's of the biomaterials..
3m Innovative Properties Company

Control of arthropod infestation

A dry powder formulation comprising spores of an entomopathogenic fungus that has activity against arthropods that infest dry commodity storage areas, wherein the spores are present in an amount of 2 to 5% w/w of the formulation; particles of an industrial mineral in an amount of 80 to 88% w/w of the formulation and having a volume mean diameter of ≧5 μm; and electret particles in an amount of 10 to 15% w/w of the formulation, and uses thereof.. .
Exosect Limited

Methods of eliminating spores

An acidic aqueous composition having a ph of from 1 to 4, for elimination of spores of spore forming bacteria, comprises from 100 to 2000 ppm dissolved chlorine dioxide, and a surfactant system having a wetting effect and a spore solubilising effect. The surfactant system comprises at least two hydrocarbon ionic surfactants stable for oxidation at the acidic ph, of which at least two surfactants have a difference in hydrocarbon chain length of at least four carbon atoms and are anionic surfactants at a ph of from 1 to 4, selected from the group consisting of soluble salts of alkyl sulphates, alkyl sulphonates, alkyl aryl sulphonates, and aryl sulphonates, having between 6 and 25 carbon atoms in the alkyl chains.
Lifeclean International Ab

Methods and solutions including additives and stabilizers for killing or deactivating spores

Exemplary methods and systems for killing or deactivating spores include applying a fluid containing an additive to a surface containing a spore; and applying direct or indirect plasma to the surface for a period of time.. .

Respirator without breathing resistance

The present invention relates to a respirator without breathing resistance, which has an air inlet duct that passes through an inside and an outside of the respirator and that has asymmetrical electrodes and particle capturing plates formed on an inner surface of the air inlet duct; ozone removing element that removes ozone generated by micro-plasma; and high voltage dc-dc converter that provides high voltage to the asymmetrical electrodes. It employs asymmetrical electrodes and particle capturing plates to filter air without generating breathing resistance.
Korea University Research And Business Foundation

Fusion proteins and methods for stimulating plant growth, protecting plants from pathogens, and immobilizing bacillus spores on plant roots

The present invention is generally directed to fusion proteins containing a targeting sequence that targets the fusion protein to the exosporium of a bacillus cereus family member. The invention also relates to recombinant bacillus cereus family members expressing such fusion proteins, formulations containing the recombinant bacillus cereus family members expressing the fusion proteins.
Spogen Biotech Inc.

Enhancer compositions for agricultural chemicals and agricultural chemical compositions

The present invention provides an agricultural chemical enhancer composition comprising a mixture of (a) a fermentation product of one or more of red beans, peas, yellow corn, white corn, white rice, yucca, potatoes, manioc root, starch from vegetables sources, inorganic minerals, non-iodized sea salt, urea or another equivalent nitrogen source, biodynamic water and an inoculum selected from the group consisting of bacillus microorgasnisms or spores and yeast; and (b) an essential oil such as banana oil, cinnamon oil, coconut oil, vanilla oil and mixtures thereof; and urea or another equivalent nitrogen source and an extract of a plant material selected from the group consisting of marranero fern foliage (pteridium aquilinum), cola de caballo (horsetail fern) leaves (esquisetum arvense), powdered cinnamon (cinnamomum zeylanicum), garlic cloves (allium sativum), tabasco pepper fruits (capsicum frutescens), pasto kikuyo seeds (pennisetum clandestinum) and mixtures thereof. The enhancer of the invention is combined with agrochemicals to augment their activity..

Bacteria and enzymes produced therefrom and methods of using same

A bacteria referred to here as bacillus subtilis 6a-1 is provided, compositions thereof and processes for use of the bacteria, spores, cells, extracts and enzymes. The compositions which comprise the bacteria, spores, cells, extracts and/or enzymes are capable of degrading polysaccharides.
Agri-king, Inc.

Bacterial spore based energy system

A method and system for providing an engine for producing mechanical energy through the absorption and evaporation of moisture uses a hygroscopic material in one or more configurations to do mechanical work. The hygroscopic material can include microbial spores, plant cells and cell materials, silk and hydrogel materials that absorb moisture and expand or swell when exposed to high relative humidity environments and shrink or return to nearly their original size or shape when exposed to low relative humidity environments wherein the moisture evaporates and is released.
President And Fellows Of Harvard College

Compositions and methods for multipurpose disinfection and sterilization solutions

The present disclosure discloses compositions and methods for multipurpose disinfection and sterilization solutions broadly effective against multiple microbial pathogens. The present disclosure demonstrates broad spectrum antimicrobial activity against environmental and pathogenic amoeba, bacterial spores, vegetative bacteria, fungi, rickettsia, viruses, parasites and toxic microbial products.
The Administrators Of The Tulane Educational Fund

Chemical inactivation of bacillus anthracis spores in soil

A method of inactivating b antracis spores in a contaminated target environment by: exposing the environment containing said spores to an effective amount of persulfate in solution and an oxidation agent, and allowing the persulfate solution and oxidation agent to remain in contact with the environment containing said spores for sufficient time to inactivate the spores.. .
Battelle Memorial Institute

Method and detecting and discriminating biological from non-biological species

This invention concerns the field of sample identification, in particular a method and apparatuses for identifying or discriminating biological species from non biological species, both as individual particles and as components of a composition, by pump-probe fluorescence spectroscopy for time-resolved detection or imaging. The method uses the finding that the uv-induced fluorescence of biological molecules is varied, in particular is depleted, by the addition of visible radiation, whereas this does not occur with non-biological organic molecules.
University Of Geneva

Methods and compositions for inhibiting clostridium difficile spore germination and outgrowth

Certain bile acids, including novel bile acids, and derivatives thereof can be used to inhibit the germination of c. Difficile spores and/or the growth of c.
Tufts University

Microbiological growth media and methods of using the same

The present invention features general-purpose microbiological growth media capable of supporting growth of microorganisms on membranes. The media contain casein digest, soybean digest, animal tissue digest, yeast extract, dextrose, a phosphate buffer, hemin, and l-cystine.
Rapid Micro Biosystems, Inc.

System and production of shelf stable probiotics for animal nutrition enhancement

Provided are shelf-stable probiotic compositions comprising endospores of bacillus with desirable characteristics such as acid resistance, high temperature tolerance, and high levels of phytase, α-amylase, cellulolytic and/or protease enzyme activities. Methods for their use, e.g.
The Board Of Regents For Oklahoma State University

Biological compositions, articles and methods for monitoring sterilization processes

A sterility indicating composition comprising a plurality of sterilization process resistant spores; a germination medium comprising a sub-lethal amount of at least one cell-permeant nucleic acid-interacting fluorescent dye and at least one nutrient for germination of the spores; wherein the at least one cell-permeant fluorescent dye can interact with nucleic acids present in and produced by the plurality of spores during germination or during germination and outgrowth of the spores to produce an increase in fluorescence intensity, indicating that viable spores are present, and wherein the cell-permeant fluorescent dye is sufficiently stable at least at a temperature for incubating the spores to produce the increase in fluorescence intensity, a sterilization process indicator comprising the composition, and a method of determining the effectiveness of a sterilization process using the composition and indicator are disclosed.. .
3m Innovative Properties Company

New anti-clostridium compounds

The present invention relates to compounds having a backbone structure for use as antibiotic, more specifically use against infections with gram positive bacteria, preferably clostridium, more preferably c. Difficile or c.
Nederlandse Organisatie Voor Toegepast-natuurweten Schappelijk Onderzoek Tno

Control of arthropod infestation using particles comprising an entomopathogen and wax

Composite particles containing hydrophobic particles and spores of an entomopathogenic fungus that are capable of germinating on the cuticle of a grain storage arthropod, dry powder compositions comprising such composite particles, methods of producing such compositions and methods and uses thereof.. .
Exosect Limited

Methods of treatment of c. difficile spores with ramoplanin

The present disclosure relates generally to methods of treatment of clostridium difficile-associated disorders and/or c. Difficile spores in the gastrointestinal tract by administering ramoplanin or a pharmaceutical formulation thereof, pharmaceutical compositions comprising ramoplanin, and therapeutic uses thereof in treating clostridium difficile-associated disorders and/or c.
Nanotherapeutics, Inc.

Methods for sterilization and/or disinfection

Methods for killing spores include contacting the spores with an aqueous solution containing performic acid. The contacting occurs at a temperature of less than or equal to about 35° c.
Performance Packaging Of Nevada, Llc

P-phenylene ethynylene compounds as bioactive and detection agents

Various embodiments relate to p-phenylene ethynylene compounds as bioactive and detection agents. In various embodiments, the present invention provides a method of inducing germination of microbial spores including contacting the microbial spores with a p-phenylene ethynylene compound.

Method and detecting and quantifying bacterial spores on a surface

A method and an apparatus for detecting and quantifying bacterial spores on a surface. In accordance with the method: bacterial spores are transferred from a place of origin to a test surface, the test surface comprises lanthanide ions.
California Institute Of Technology

Multivalent stable vaccine composition and methods of making same

Stable immunogenic composition capable of eliciting a robust and durable immune response yielding a measurable increase in neutralizing antibodies at least 200 days post-administration, comprising at least one antigen consisting of a ribosome inactivating protein and at least one antigen comprising a toxin derived from bacterial spores. Method making and using a stable immunogenic composition capable of eliciting a stable immune response yielding a measurable increase in neutralizing antibodies at least 200 days post-administration, comprising providing an immunogenic composition comprising at least one antigen comprising a ribosome inactivating protein and at least one antigen comprising a toxin derived from bacterial spores and administering the immunogenic composition to an individual..
Soligenix, Inc.

Nylon-3 polymers active against clostridium difficile

A method and corresponding composition to inhibit outgrowth of c. Difficile spores and/or to inhibit growth of c.
Emory University

Wipe for killing spores

This invention relates to a wipe for killing spores comprising an absorbent sheet holding an aqueous composition and a sealed package containing the absorbent sheet, wherein the aqueous composition comprises water, an antimicrobial agent and a peroxide. The invention also relates to a process for killing spores using the above-indicated wipe..
American Sterilizer Company

Solid-state biological reaction device and preparing filamentous organism spores by using the same

A solid-state biological reaction device, comprising a main tank body and a collector is provided. A top air outlet, a bottom air inlet and a material entrance and exit are provided on the main tank body.
Tianjin Institute Of Industrial Biotechnology, Chinese Acadamy Of Sciences

Proportioner-ready bioenzymatic concentrated cleaning product

A concentrated bioenzymatic cleaning product is provided which maintains a homogenous composition under static conditions and does not require shaking or mixing prior to dilution. The concentrated bioenzymatic cleaning product includes bacillus spores, a suspending and/or rheology modifying agent, an odor control agent, a ph adjuster, and water.
Illinois Tool Works Inc.

Nanocarrier based plant transfection and transduction

The present invention provides a novel method for the transduction and/or transfection of plant cells. Cell-penetrating peptides (cpps) have been successfully employed as nanocarriers to deliver proteins and oligonucleotides to single plant cell microspores as well as multi-cellular zygotic embryos.
Her Majesty The Queen In Right Of Canada As Represented By The Minister Of Agriculture And Agr

Process for preparing polyphenylene ether microspore dispersion

A process for preparing ppe microspore dispersion includes steps of: dissolving a high-molecular polyphenylene ether in a first solvent at 45-110° c. To form a dissolution liquid; adding processing aids and well mixing the dissolution liquid into a dispersed phase; cooling the dissolution liquid to 42-80° c., and adding a second solvent to generate ppe microspores via ppe to wrap around the processing aids; cooling the dissolution liquid to 0-40° c.
Nan Ya Plastics Corporation

Method of treating fruit pressing residue

A method of treating fruit pressing residue to avoid formation of germ-buds and mold, more particularly aflatoxins, is disclosed. The treatment includes storing fruit pressing residue (pomace) at a controlled temperature, and calibrating the residue to a homogeneous size.

Post-harvest coating for fresh produce

An antimicrobial coating material for post-harvest coating of produce includes a mixture of an acid component and a film-forming carbohydrate. A method for post-harvest treatment of produce includes applying a coating material onto produce after harvest and cleaning, thereby producing an antimicrobial coating in the form of an encapsulating film on the surface of the produce.
Jones-hamilton Co.

Composition and methods to control the outgrowth of pathogens and spoilage microorganisms in high moisture and low sodium systems

The invention describes a method of inhibiting the outgrowth of pathogens and spoilage microorganisms in high moisture (65-80% by weight) and low salt (<2.0% by weight) nutrient dense environments with a ph range of 5.5 to 8.5. The application of an organic acid or its salt with a fermentation derived antimicrobial peptide offers a robust solution to curtail growth of spores and vegetative cells without the need for chemicals such as sodium nitrite or nitrate..
Kerry Luxembourg S.a.r.l.

Lactobacillus plantarum inducia dsm 21379 as enhancer of cellular immunity, hypocholesterolemic and anti-oxidative agent and antimicrobial agent against clostridium difficile

A microorganism strain lactobacillus plantarum inducia dsm 21379 for use as hypocholesterolemic, antimicrobial and anti-oxidative agent and as enhancer of the natural defense potential of a subject. L.
Tervisliku Pllma Biotehnoloogiate Arenduskeskus OÜ (bio-competence Centre Of

System and methods for continuous propagation and mass production of arbuscular mycorrhizal fungi in liquid culture

The present invention relates to a method and a system for the production of arbuscular mycorrhizal fungi (amf). More specifically, the invention described herein relates to a method and a system for the continuous in vitro culture of arbuscular mycorrhizal fungi, preferably including steps of harvesting and/or passaging.
Symplanta Gmbh & Co Kg

Apparatus to control reaction of peroxide and alkaline

The present invention relates to an apparatus designed to control the application of the previously uncontrollable reaction of a peroxide composition and an alkaline composition, and accurately maintain the desired composition ratios for removal of and destruction of microbiological and organic contamination on a surface safely and without waste of the materials. The apparatus may also be used to maintain the highest demulsifying and antimicrobial activity of an organic acid composition blended with a peroxide composition by limiting contact time and the level of degradation of the components of the organic acid composition.

Compositions and methods for prophylaxis and therapy of clostridium difficile infection

Provided are compositions and methods for prophylaxis and/or therapy of c. Difficile infection, and for inhibiting dissemination of c.
The Rockefeller University

Methods for dispensing salt-free hypochlorous acid for hand-sanitizing

Taught herein is a method and means of sanitizing a person's hands using an anti-microbial, salt-free, non-allergenic, non-toxic hypochlorous acid (hoci) hand-sanitizing compound applied to a user's hand by a hand-sanitizer dispenser. The dispenser is either automatic or manual and is operated from a wall-mounted dispenser, a table-top-mounted or a free standing unit.

Culture medium containing a spore germination inhibiting or delaying compound

A medium for the culture and detection of target microorganisms, having at least one natural or synthetic specific substrate configured to detect at least one enzyme activity or metabolic activity of the target microorganisms and at least one compound that inhibits or delays the germination of spores of microorganisms, other than the target microorganisms, that are capable of interfering with the culture and detection of the target microorganisms.. .
Biomerieux

Mineral complex, compositions, methods of making, and uses therein

The present invention relates to agriculture and fertilization. In particular, compositions and methods relating to soil amendments, crop fertilization, plant fertilizers, organic waste management, and biocidal mixtures used to kill or inhibit fungi or fungal spores, molds, and mildews, and/or insect infestations applicable for treating crops are provided.
Heart Of Nature Llc

Agricultural composition containing chitin and chitinase-producing bacteria for treating soil and plants

A composition for protecting plants against chitinous pathogens and/or treating infestations of chitinous pathogens comprises pellets which include a source of chitin and a bacteria capable of producing chitinase. In certain embodiments, the bacteria are in the form of spores.

Isolated strain of clonostachys rosea for use as a biological control agent

Described is an isolated strain of the fungus colonostachys rosea termed bvt cr-7 useful as a biological control agent for the treatment of plants. The isolated strain, formulations comprising said strain and/or spores derived from said strain may be applied to plants or plant materials in order to improve plant yield, to improve plant growth, or for the treatment or prevention of diseases or pathogens in the plant..
Bee Vectoring Technology Inc.

Haploid embryogenesis

A switch to haploid embryogenesis is controlled by the activity of histone deacetylases (hdacs). Blocking hdac activity with hdac inhibitors (hdaci), e.g.
Stichting Dienst Landbouwkunding Onderzoek

Two-stage sterilization process for treating heat-resistant spores in great burdock extract drink

The present invention is to provide a two-stage sterilization process for treating heat-resistant spores in a great burdock extract drink, which comprises the steps of sealing dried great burdock and water in a double-kettle pressure cooker; heating liquid mixture of great burdock and water to a first temperature range lower than or equal to 100° c. For at least a first duration during a first-stage sterilization; opening lid of the cooker and filtering out great burdock residue so that all that remains in the cooker is great burdock extract; resealing the cooker and heating the great burdock extract to a second temperature range higher than or equal to 120° c.
Burdock Biotech Taiwan Co., Ltd.

Compositions and methods

Disclosed herein are therapeutic compositions containing non-pathogenic, germination-competent bacterial spores, for the prevention, control, and treatment of gastrointestinal diseases, disorders and conditions and for general nutritional health.. .
Seres Therapeutics, Inc.

Compositions comprising bacillus strains and methods of use to suppress the activities and growth of fungal plant pathogens

This invention provides compositions of bacillus strains and methods for using such compositions to inhibit the activity and/or growth of fungal pathogens of plants. In one embodiment, this invention provides a composition comprising bacillus bacteria selected from the group consisting of brevibacillus laterosporus strain cm-3, brevibacillus laterosporus strain cm-33, bacillus amyloliquefaciens bcm-cm5, bacillus licheniformis atcc-11946, bacillus mojavensis bcm-01, bacillus pumilus nrrl-1875, bacillus subtilis 10 dsm-10, bacillus subtilis nrrl-1650, bacillus megaterium bcm-07, paenibacillus polymyxa dsm-36, paenibacillus chitinolyticus dsm-11030, and combinations thereof.
Bio-cat Microbials Llc

Compositions and methods

Disclosed herein are therapeutic compositions containing non-pathogenic, germination-competent bacterial spores, for the prevention, control, and treatment of gastrointestinal diseases, disorders and conditions and for general nutritional health.. .

Planting matrices comprising bacillus spp. microorganisms for benefiting plant growth

Compositions are provided that are planting matrices containing spores of bacillus spp. Microorganisms for benefiting plant growth.

Method for producing vegetable products using ultra high pressure

The present invention relates to a method for producing vegetable products, which effectively sterilizes fungi, yeast, pathogenic bacteria, spores of a sporogenic microorganism, etc. Growing in raw vegetables and cooked vegetables, using a non-heat-treated ultra-high pressure sterilization process..

Methods, formulations, and kits for bacterial degradation

Methodologies, formulations, and kits suitable for decontaminating environments containing bacterial spores by degrading the spores. Formulations contain papain, at least one germinant, and optionally one or more additional enzymes.

Methods of eliminating spores

Methods of eliminating spores of spore forming bacteria from the genus clostridium on a surface comprise contacting the surface with an effective amount of an acidic aqueous composition having an acidic ph of from about 1 to about 4 and comprising from about 100 to about 2000 ppm dissolved chlorine dioxide, and a surfactant system having wetting effect and a spore solubilising effect. The surfactant system comprises at least two hydrocarbon ionic surfactants stable for oxidation at the acidic ph, of which at least two surfactants have a difference in hydrocarbon chain length of at least four carbon atoms..
Lifeclean International Ab

Ligand functional substrates

A substrate comprising a crosslinked polymer primer layer, and grafted thereto a ligand-functionalized polymer is provided. The grafted polymer has the requisite affinity for binding neutral or negatively charged biomaterials, such as cells, cell debris, bacteria, spores, viruses, nucleic acids, and proteins, at ph's near or below the pi's of the biomaterials..
3m Innovative Properties Company

Nanoparticulate titanium dioxide nanomaterial modified with functional groups and with citric extracts adsorbed on the surface, for the removal of a wide range of microorganisms

A conjugate of a titanium dioxide nanomaterial and nanoparticulate herbal and/or fruit extracts is synthesized by impregnation, using titanium dioxide as support, to which are adsorbed organic functional groups, inorganic radicals and plant extracts that confer thereon anti-microbial properties with high disinfectant and antiseptic power, removing bacteria, fungi, mycobacteria, spores, mycobacteria, protozoa and viruses. The conjugate is a solid nanomaterial in liquid suspension and is prepared by impregnation to disperse the functional groups and the extract particles, with temperature control to stabilize the interactions within the network of the support.
Inmolecule International Limited

Compositions and methods with efficacy against spores and other organisms

Compositions and methods for the disinfection of surfaces are provided. The compositions include at least about 40 weight percent of a c1-6 alcohol, and a primary enhancer selected from protein denaturants.
Gojo Industries, Inc.

Shelf stable, reduced corrosion, ready to use peroxycarboxylic acid antimicrobial compositions

The present invention relates to shelf stable and/or less corrosive peroxycarboxylic acid antimicrobial compositions, including ready-to-use compositions. Shelf stable compositions can include defined ratios of hydrogen peroxide to peroxycarboxylic acid and/or hydrogen peroxide to protonated carboxylic acid, but need not include strong acid.
Ecolab Usa Inc.

Process for the therapeutic management of diarrhea predominant irritable bowel syndrome using bacillus coagulans sbc-37-01, mtcc 5856

The present invention discloses a process for the therapeutic management of diarrhea predominant irritable bowel syndrome in humans comprising the oral administration of bacillus coagulans sbc37-01, mtcc 5856 (containing not less than 2 billion spores) along with standard treatment of care in a specific manner.. .

Targets and compositions for use in decontamination, immunoprophylaxis, and post-exposure therapy against anthrax

The present invention relates to the decontamination of anthrax spores, prophylaxis and treatment of anthrax infections and, more particularly, to compounds that act as specific inhibitors of b. Anthracis germination/outgrowth-associated proteins, methods and means for making such inhibitors and their use as pharmaceuticals and/or vaccines.
Altimmune Inc.

Spray formulation and its use in plant protection

The present invention relates in a first aspect to a spray formulation. In particular, said spray formulation is a spray formulation adapted for colonisation of plants with spores of endophytes, in particular, entomopathogenic endophytes.
Fachhochschule Bielefeld

Nanostructured spore carrier

spore carriers suitable for use in biological indicators are described. The spore carriers include a substrate such as polymeric film or non-woven web with a hydrophilic nanostructured layer bonded to it.
3m Innovative Properties Company

Methods for detecting and quantifying viable bacterial endo-spores

Methods and systems for detecting viable bacterial endospores in a sample and related methods to quantify viable bacterial endospores in a sample.. .
California Institute Of Technology

Stable fungal blastospores and methods for their production, stabilization and use

Described herein is a method for blastospore-based insect control products of entomopathogenic fungi including either b. Bassiana or i.
Embrapa

Systems and methods for genotyping seed components

The invention provides methods for obtaining genetic material from plant embryos while preserving their viability as well as methods for performing a molecular analysis of plant embryos, particularly with small quantities of genetic material. The methods may include the steps of collecting shed cellular material from one or more plant embryos; obtaining dna from the shed cellular material; performing a molecular analysis of the dna; and germinating at least one of said one or more plant embryos.
Pioneer Hi Bred International Inc

Systems and methods for genotyping seed components

The invention provides methods for obtaining genetic material from plant embryos while preserving their viability as well as methods for performing a molecular analysis of plant embryos, particularly with small quantities of genetic material. The methods may include the steps of collecting shed cellular material from one or more plant embryos; obtaining dna from the shed cellular material; performing a molecular analysis of the dna; and germinating at least one of said one or more plant embryos.
Pioneer Hi Bred International Inc

Clostridium difficile sporicidal compositions

Disclosed are sporicidal compositions, and methods of use thereof. The sporicidal compositions contain water, an organic solvent, and a spore-germinating agent containing an iodide source, a citrate source or both.
Microdermis Corporation

Process for increasing biomass and spores production of plant growth promoting bacteria of the bacillus genus

The present invention refers to a process designed to increase the production of plant growth-promoting microorganisms of the bacillus genus, using a culture medium poor in nutrients and with specific environmental conditions, allowing to obtain a greater amount of biomass and/or spores, which can be used to prepare solid or liquid compositions to be applied to plants, aiming to promote their growth and/or counteract the effect of phytopathogenic agents.. .
AsociaciÓn De Bananeros De Colombia (augura)

Composition, device, and biological air sampling

The present invention generally relates to air sampling of biological compounds. Specifically, the present invention relates to a device and method for sampling the ambient air for detecting microbial propagules, microbial propagules being any spore, vegetative cell, or virion of microbiological origin including all bacteria, fungi, viruses, protozoans, molds, slime molds, chlamydospores, hyphae, and cysts..

Fusion proteins and methods for stimulating plant growth, protecting plants, and immobilizing bacillus spores on plants

The present invention is generally directed to fusion proteins containing a targeting sequence that targets the fusion protein to the exosporium of a bacillus cereus family member. The invention also relates to recombinant bacillus cereus family members expressing such fusion proteins and formulations containing the recombinant bacillus cereus family members expressing the fusion proteins.
Spogen Biotech Inc.

Apparatus for performing sonication

An apparatus for performing sonication on liquid samples comprises a rack for holding an array of sample vials, an ultrasonic probe with an arrangement of recesses corresponding to the array of sample vials and adapted to respectively receive and contact an outer surface of a bottom portion of a respective one of the sample vials, and a counter-holder with an arrangement of pushing members corresponding to the array of sample vials and adapted to respectively apply a force to a respective one of the sample vials so as to push the bottom portion of each vial into contact with the associated recess of the probe. The apparatus can be used in a method of preparing a sample for detection of cell components (e.g.
Merck Patent Gmbh

Methods and solutions for rapidly killing or deactivating spores

Exemplary methods and systems for killing or deactivating spores include applying a fluid to a surface containing a spore; and applying direct or indirect plasma to the surface for a period of time. In some embodiments, the fluid includes water.
Ep Technologies Llc

Methods and groups

A method, for the identification of bacterial isolates suitable for use in bacteriotherapy, the method comprising: (i) preparing a suspension of material collected from a host harbouring microbiota; (ii) addition of an activator of bacterial spores sufficient to allow growth of bacteria from spores present in the suspension; (iii) culturing the suspension; and (iv) identification of at least one bacterial species within the culture.. .
Genome Research Limited

Wipe for killing spores

This invention relates to a wipe for killing spores comprising an absorbent sheet holding an aqueous composition and a sealed package containing the absorbent sheet, wherein the aqueous composition comprises water, an antimicrobial agent and a peroxide. The invention also relates to a process for killing spores using the above-indicated wipe..
American Sterilizer Company

Microcapsules and concrete containing the same

Microcapsules, for inclusion in concrete, adapted to reduce the area of a defect by at least 45% in said concrete once a quantity of said microcapsules has ruptured, said micro-capsules each comprising: a polymeric shell encapsulating a liquid core, wherein the polymeric shell comprises a substantially impermeable polymer layer and the liquid core comprises carbonatogenic bacterial spores, and optionally bacterial nutrients, dispersed in a liquid medium. Also disclosed is a concrete composition comprising a quantity of such microcapsules, and a method of reducing the area of a defect in concrete..
Universiteit Gent

Monolayer food product and methods

Embodiments of the invention include food products and related methods. In an embodiment, the invention includes a method for producing a food product.
Wm. Bolthouse Farms, Inc.

Endospore detection using hydrophobic collection material

In situ optical analysis of bacterial endospores can be inhibited when the endospores are present within an optically active carrier medium. To help isolate the endospores from the carrier medium, in some examples, the carrier medium is passed through a hydrophobic material that captures the endospores via hydrophobic attraction.
Ecolab Usa Inc.

Process and composition for killing spores

This invention relates to an aqueous composition and a process for killing spores. The process may comprise contacting the spores with the aqueous composition for a sufficient period of time to effect a desired reduction (e.g., at least a 4 log reduction) in the number of spores capable of returning to vegetative growth.
American Sterilizer Company

High pressure processing of juice containing probiotics

The objective of the invention is to provide an improved method of making healthier juice products inoculated with probiotics, wherein the juice includes but is not limited to apple juice, coconut water, coconut milk, orange juice and/or carrot juice. The present invention relates to a method of pressure treating a juice containing probiotics.
Chic Group Co., Ltd.

Chemical inactivation of bacillus anthracis spores in soil

A method for the inactivation of b. Anthracis spores in soil comprising contacting the soil with an effective amount of a persulfate and an activator for a time sufficient to inactivate substantially all of the b.
Battelle Memorial Institute

Sprayable dispersed starch-based bioplastic formulation to control pests

A sprayable liquid biodegradable formulation comprising biocontrol microorganisms imbedded in a dispersed starch-based bioplastic is effective for delivering biocontrol microorganisms and bioactive compounds to soil, crops and seeds and facilitating positioning of biocontrol agents in close proximity to target pests. After application with conventional spray equipment, water evaporates rapidly and the dispersed bioplastic formula remains, serving as a prolonged growth substrate for the biocontrol microorganisms.
Alma Mater Studiorum- Università Di Bologna

Method for drying biomaterials

The present invention provides a means to concentrate, dry and formulate biomaterials such as polysaccharides, gums and related biopolymers, and microorganisms such as cells, spores, and the like from dilute solutions using spent germ and other oil bearing residues. In addition, the spent germ can serve as a carrier for such biomaterials.
Grain Processing Corporation

Spore detector

A system and method of detecting spores includes a light source configured to emit a light pulse within a first wavelength range, and a light sensor configured to detect a resulting phosphorescence emitted from one or more desiccated spores phosphorescing within a second wavelength range in a vicinity of the light pulse. The spore detector also includes circuitry configured to trigger emission of the light pulse and record the emitted phosphorescence at a pre-determined time after the light pulse..
Lockheed Martin Corporation

Process for decontaminating or sterilizing an article

This invention relates to a a process for decontaminating or sterilizing an article contaminated with spores. The process comprises contacting the spores with a liquid sterilant for a sufficient period of time to effect a desired reduction (e.g., at least a 4 log reduction) in the number of spores capable of returning to vegetative growth.
American Sterilizer Company

Decontamination or sterilization process

This invention relates to a decontamination or sterilization process wherein spores are killed, comprising: forming droplets of an aqueous composition comprising water and a peroxide, the aqueous composition having a concentration of peroxide in the range from about 0.01 to about 14% by weight; vaporizing the droplets to form a sporicidal vaporous mixture; and contacting the spores with the sporicidal vaporous mixture for a sufficient period of time to effect at least a 4 log reduction in the number of spores capable of returning to vegetative growth.. .
American Sterilizer Company

Process and composition for killing spores

This invention relates to an aqueous composition and a process for killing spores. The process may comprise contacting the spores with the aqueous composition for a sufficient period of time to effect a desired reduction (e.g., at least a 4 log reduction) in the number of spores capable of returning to vegetative growth.
American Sterilizer Company

Process and composition for killing spores

This invention relates to a process and an aqueous composition for killing spores. The process comprises contacting the spores with the aqueous composition for a sufficient period of time to effect a desired reduction (e.g., at least a 4 log reduction) in the number of spores capable of reproduction, metabolism and/or growth.
American Sterilizer Company

Compositions for the restoration of a fecal microbiota and methods for making and using them

In alternative embodiments, the invention provides compositions and methods for treating various disorders and conditions in mammals, including chronic disorders in which there is a presence of an abnormal microbiota or an abnormal distribution of microflora in the gastrointestinal tract. In alternative embodiments, the invention provides liquid preparations or formulations derived from a human fecal material (e.g., a stool) processed, e.g., filtered and/or centrifuged, such that all bacteria, fungal spores and viruses are removed, but retaining the native biologically active molecules from the fecal material and bacteriophages.

Process to make pelletized granules based on endomycorrhizal fungi covered with minerals clays and their composition

The present invention relates to a composition of granulated or pelletized endomycorrhizal fungi spores coated with a covering of mineral clays and binders with calcium sulphate monohydrate and the production and use thereof in agriculture.. .

Photocatalytic air treatment system and method

A photocatalytic air treatment system, including apparatuses and methods, for killing and/or mineralizing bacteria, viruses, mold, fungi, spores, mycotoxins, allergens, and other similar microorganisms or agents, and for oxidizing volatile organic compounds (vocs). The system comprises one or more reactor beds configured in one or more stages with each reactor bed including a plurality of photocatalyst coated media substantially surrounding a plurality of sheathed ultraviolet light sources that may be arranged in a plurality of configurations.

Materials and methods for controlling nematodes with pasteuria spores in seed coatings

The subject invention provides novel and advantageous materials and methods for controlling phytopathogenic and/or soil-dwelling nematodes by attaching an effective amount of pasteuria spores to a seed and delivering the seeds to the situs of nematodes.. .
Syngenta Crop Protection Ag

Methods and solutions for killing or deactivating spores

Exemplary methods and systems for killing or deactivating spores include applying a fluid to a surface containing a spore; and applying direct or indirect plasma to the surface for a period of time. In some embodiments, the fluid includes water.
Ep Technologies Llc

Anthrose-based compositions and related methods

This invention provides a vaccine comprising (i) an anthrose-containing saccharide in an amount effective to enhance immunity against bacillus anthracis in a subject and (ii) a pharmaceutically acceptable carrier. This invention provides a vaccine comprising (i) a conjugate of an anthrose-containing saccharide in an amount effective to enhance immunity against bacillus anthracis in a subject, wherein the anthrose-containing saccharide is conjugated to a biomolecule via a linker, and (ii) a pharmaceutically acceptable carrier.

Method for removing particulate matter in indoor environments

Method for removing all types of particulate matter with exclusion of biological multiplying microorganisms in indoor environments characterized by comprising the following two steps:—the atomization of compounds that oxidize particulate matter to form complexes and to precipitate them;—the atomization of a liquid containing a mixture of spores of gram-positive aerobic and/or of facultative anaerobic spore formers to act as nuclei for extra precipitation, to cover the precipitated particulate matter; and to metabolize precipitated particles and to take up precipitated particles by the gram-positive bacteria/thereby preventing the precipitated particles to become airborne again;—whereby the drop size in both atomization steps is held between 5 and 50 μm to yield a dry nebula.. .
Living Technologies, Cooperatieve Vennootschap Met Beperkteaansprakelijkheid

Reverse synthesis of breeding lines

The invention relates to a method for producing parental lines for a hybrid organism. This method is based on the segregation of individual alleles in the spores produced by a desired plant and/or in the progeny derived from the self-pollination of that desired plant, and on the subsequent identification of suitable progeny plants in one generation, or in a limited number of inbred cycles.
Rijk Zwaan Zaadteelt En Zaadhandel B.v.

Compositions and methods with efficacy against spores and other organisms

Compositions and methods for the disinfection of surfaces are provided. The compositions include at least about 40 weight percent of a c1-6 alcohol, and a primary enhancer selected from protein denaturants.
Gojo Industries, Inc.

Assays

A device comprising a rigid substrate, a flexible cover element at least partially covering the substrate, a first structure formed in the substrate, adapted for accommodating liquids and adapted for releasing contents of one or more cells, spores, or viruses, the contents including the target molecules, a second structure formed in the substrate, adapted for accommodating liquids and comprising at least one binding member adapted for capturing the target molecules and for determining a value indicative of the presence and/or amount of the target molecules, a micro fluidic network interconnecting at least the first structure and the second structure, and an actuator member adapted for effecting a fluid flow between the first structure and the second structure by pressing the flexible cover element against the substrate to selectively close a portion of the micro fluidic network.. .
Clondiag Gmbh

Control of arthropod infestation using particles comprising an entomopathogen and wax

Composite particles containing hydrophobic particles and spores of an entomopathogenic fungus that are capable of germinating on the cuticle of a grain storage arthropod, dry powder compositions comprising such composite particles, methods of producing such compositions and methods and uses thereof.. .
Exosect Limited

Washing machine deodoizer

A method to control odors in an interior of a laundry washing machine by applying to surfaces of the interior of the washing machine a bacterial composition comprising bacterial spores capable of germinating into active bacteria which inhibit or prevent the production of at least one microorganism capable of causing odor.. .
Weiman Products, Llc

Modulating germination of paenibacillus larvae

Materials and methods for stimulating or inhibiting germination of paenibacillus larvae spores, including methods for inhibiting p. Larvae germination to reduce foulbrood in honey bees..
The Board Of Regents Of The Nevada System Of Higher Education On Behalf Of The University

Biological sterilization indicator, system, and methods of using same

A biological sterilization indicator, system, and methods of determining the effectiveness of a sterilization process. The biological sterilization indicator can include a locus of spores, a reservoir containing a liquid, and a sterilant path positioned to provide fluid communication between ambience and the locus of spores.
3m Innovative Properties Company

Non-caloric probiotic composition and preparation

A probiotic composition comprising at least one viable probiotic microorganism having a biological or therapeutic activity in the gastrointestinal tract and a carrier suitable for human consumption is disclosed. The probiotic composition may contain drinking water and electrolytes and the probiotic microorganism may be spores of a probiotic microorganism.
K&k Ventures, Llc

Method and device for the concentration of multiple microorganisms and toxins from large liquid toxins

A method for the simultaneous concentration of multiple toxins from large volumes of water. The method includes the steps of providing a disposable separation centrifuge bowl, the centrifuge bowl including a positively charged material at it's inner core.
Trustees Of Tufts College

Method for drying biomaterials

The present invention provides a means to concentrate, dry and formulate biomaterials such as polysaccharides, gums and related biopolymers, and microorganisms such as cells, spores, and the like from dilute solutions using spent germ and other oil bearing residues. In addition, the spent germ can serve as a carrier for such biomaterials.
Grain Processing Corporation

Graft copolymer functionalized article

Guanidinyl ligand-functionalized polymers, methods of making the same, and substrates bearing a grafted coating of the ligand-functional polymers are described. The grafted polymer has the requisite affinity for binding neutral or negatively charged biomaterials, such as cells, cell debris, bacteria, spores, viruses, nucleic acids, endotoxins and proteins, at ph's near or below the pi's of the biomaterials..
3m Innovative Properties Company

Steam treating of fodder

An apparatus for and method of steam treatment of fodder, for example animal fodder which is typically in baled form. The purpose of steam treating is to kill mesophilic and thermophilic mould spores that are either attached to the fodder or detach when disturbed and become airborne.
Propress Equine Limited

Use of saccharides cross-reactive with bacillus anthracis spore glycoprotein as a vaccine against anthrax

Provided are immunogenic compositions and methods for eliciting an immune response against b. Anthracis and other bacteria that contain 3-methyl-3-hydroxybutyrate- or 3-hydroxybutyrate-substituted saccharides.
National Research Council Of Canada

Compositions and methods

Disclosed herein are therapeutic compositions containing non-pathogenic, germination-competent bacterial spores, for the prevention, control, and treatment of gastrointestinal diseases, disorders and conditions and for general nutritional health.. .
Seres Health, Inc.

Compositions and methods comprising carboxylic acid-containing small molecules

Disclosed are compositions and methods for treating anthrax, inhibiting anthrax toxins and inhibiting anthrax toxin-induced cytotoxicity. Carboxylic acid-containing small molecules can be used in the methods and compositions disclosed herein, for example, sulindac and derivatives thereof may be used.
University Of Central Florida Research Foundation, Inc.

Use of botrytis cinerea for obtaining gold nanoparticles

The present invention is related to the use of botrytis cinerea strains, its spores, hyphae mycelium, sclerotia, intra and/or extracellular organic molecules, such as proteins, nucleic acids, polysaccharides, lipids and secondary metabolites for the biosynthesis of gold nanoparticles (aunps). In general terms, the present invention is focused to use b.
Universidad De Santiago De Chile

Control of ground surface radiative effects

Here invented is method and apparatus for control of ground surface radiative effects. A material is laid out in a field in anticipation of frost or in expectation of crop damage from powdery mildew.

Mycological biopolymers grown in void space tooling

A mycological biopolymer product consisting entirely of fungal mycelium is made by inoculating a nutritive substrate with a selected fungus in a sealed environment except for a void space, which space is subsequently filled with a network of undifferentiated fungal mycelium. The environmental conditions for producing the mycological biopolymer product, i.e.

Sterilization method

It is intended to provide a sterilization method for heat-resistant bacterial spores, with which an effective sterilization effect is attained under heating conditions milder than conventional conditions, and which hardly affects the quality of an object to be sterilized. The sterilization method includes performing a first heat treatment step having the main object of damaging spores and then performing a second heat treatment step having the main object of inactivating the damaged spores and being performed at a temperature lower than that of the first heat treatment step..
Meiji Co., Ltd.

Compositions and methods for inhibiting endospores using green tea polyphenols

Compositions and methods of killing, inactivating, or otherwise reducing the spores such as bacterial spores are disclosed. The methods typically include reducing or preventing spore reactivation comprising contacting spores with an effective amount of one or more green tea polyphenols (gtp), one or more modified green tea polyphenols (ltp), or a combination thereof.
Seton Hall University

Method of identification of spore-forming bacillus spp. by direct in-situ analysis of maldi-tof mass spectrometry, and analysis system

A method of the identification of bacillus species by direct in-situ analysis of maldi-tof ms (matrix-assisted laser desorption/ionization time-of-flight mass spectometry) in which spore-forming bacteria are applied intact without any pretreatment, and an analysis system of distinctive biomarkers which allow bacillus spores to be distinguished. Rapid and accurate detection and identification of bacillus species can be achieved by the method and analysis system..
Agency For Defense Development

Open top liquid/gas cyclone separator tube and process for same

Open top liquid/gas cyclone separator tube with a dual purpose single separator tube with both liquid and gas separation zones, an open top discharge vent to provide a for humid air to be discharged into the atmosphere, a means to prevent splashing out the open top of the separator tube, a means of the separation section to prevent turbulence while allowing the accumulation of used water in the bottom of the tube, a to provide gravity feeding of the water back to the scrubbing mechanism to be recycled for water preservation, a means of regulating the rate of water feed to the scrubbing mechanism, an open port means of the scrubbing mechanism to be used to add chemicals, gases or other elements to the gas stream that is discharged to the environment, and a for vertical discharge on the scrubbing mechanism to enhance entrainment of water droplets containing particles, bacteria and mold spores.. .

Biocontrol microorganisms

Methods, devices, and compositions described herein are directed to artificially evolving an organism for use as a biocontrol agent. Methods, devices, and compositions described herein are useful for evolving a microorganism to acquire traits not naturally associated with the microorganism.

Method of killing insects and their larvae and spores using a combination of high temperature steam and liquid nitrogen

A method and system of killing objects wherein said objects are selected from the group consisting of pests, insects, fungus and spores wherein said objects have a starting temperature, to, and said method and system comprising a first step being application of a means of raising the temperature of said objects by the exposure to heat and water vapor until said objects have reached a temperature th above said starting temperature, and said method and system comprising a second step being application of a means of lowering the temperature of said objects until said objects have reached a temperature tc below the starting temperature, and said objects being rendered lifeless after experiencing the change in temperatures with respect to time.. .

Methods and assays of bacterial spores

Described herein are methods and apparatus for assays of bacterial spores. In particular, methods and apparatus for lateral flow immunoassay for bacterial spore detection and quantification, live/dead assay for bacterial spores, lifetime-gated measurements of bacterial spores and imaging bacterial spores using an active pixel sensor, and unattended monitoring of bacterial spores in the air are described..
California Institute Of Technology

Method for producing alcohol using tree as starting material and alcohol solution obtained by same

A method is provided for the production of alcohol from trees, the method comprising a step of treating a subject tree with mother cell lyases formed through cytolysis associated with sporulation of spore-forming aerobic bacteria, thereby degrading said tree into a powdery state and obtaining a tree degradation product; a step of sterilizing said tree degradation product; a step of treating said sterilized tree degradation product with a koji fungus (aspergillus oryzae) thereby carrying out a primary fermentation; a step of adding a yeast to the fermentation broth obtained by said primary fermentation thereby carrying out a secondary fermentation; and a step of filtering the fermentation broth obtained by said secondary fermentation, wherein said mother cell lyases are obtained by culturing said spore-forming aerobic bacteria, subjecting the resultant culture medium to a starvation state, thereby converting said bacteria into endospores, and removing impurities including said endosporic bacteria from said culture medium and wherein said spore-forming aerobic bacteria are mre symbiotic bacteria.. .
Meisho Co., Ltd

Sterility indicating biological compositions, articles and methods

A sterility indicating composition comprising a plurality of sterilization process resistant spores which contain an active protease during germination and initial outgrowth of the spores; and a germination medium comprising at least one labeled protease substrate and at least one nutrient for germination of the spores; wherein the medium is essentially free of a) any active protease other than the active protease contained by the plurality of spores and b) any protease substrate other than the at least one labeled protease substrate, other than any protease substrate originating from the plurality of spores, and other than any protease substrate which does not compete with the labeled protease substrate for the active protease; and wherein the at least one labeled protease substrate comprises a peptide which can be cleaved by the active protease and which is labeled with one or more dye groups, at least one of which undergoes a detectable change when the peptide is cleaved by the active protease, and wherein the labeled protease substrate is stable at least at a temperature for incubating the spores, a sterilization process indicator comprising the composition, and a method of determining the effectiveness of a sterilization process using the composition and indicator are disclosed.. .
3m Innovative Properties Company

Products and methods

The invention relates to fungal cells and spores, as well as extracts of either, for use, in particular, in prevention or treatment of chlamydia, or helicobacter pylori or other infections, inflammation, inflammatory, lysosomal, acidic, sod- or igg or other immunoglobulin—peroxidases or hydrogen peroxide induced or other forms of oxidative damage, atherosclerosis, heart disease, stomach, intestinal and liver inflammatory conditions and their complications, promoting or stimulating regeneration or healing of wounds, burns, ulcers, or other forms of damaged or aged tissues, or in reducing elevated cholesterol and/or triglycerides levels in a preferred instance, the fungal cells or spores are those used in the manufacture of fungal fermented cheeses or other food stuff or beverages, particular fungal blue or white cheeses.. .
Ip Science Limited

Biological contamination modeling of surfaces in hot humid air

The proportion response p(x) of inactivated spores quantifies long odds spore inactivation, xj represents a set of independent variables, βj denotes a correlation coefficient from j=0, 1, . .

Antibodies to clostridium difficile spores and uses thereof

The present invention provides antibodies that bind to the endospore of the bacterium clostridium difficile, methods of making such antibodies, and methods of using such antibodies, including methods of detecting c. Difficile endospores..

Lactobacillus plantarum inducia dsm 21379 as enhancer of cellular immunity, hypocholesterolemic and anti-oxidative agent and antimicrobial agent against clostridium difficile

A microorganism strain lactobacillus plantarum inducia dsm 21379 for use as hypocholesterolemic, antimicrobial and anti-oxidative agent and as enhancer of the natural defense potential of a subject. L.

Combination bacteriolytic therapy for the treatment of tumors

Current approaches for treating cancer are limited, in part, by the inability of drugs to affect the poorly vascularized regions of tumors. We have found that spores of anaerobic bacteria in combination with agents which interact with microtubules can cause the destruction of both the vascular and avascular compartments of tumors.

Compositions and methods

Disclosed herein are therapeutic compositions containing non-pathogenic, germination-competent bacterial spores, for the prevention, control, and treatment of gastrointestinal diseases, disorders and conditions and for general nutritional health.. .

Microprojectile bombardment transformation of brassica

The invention relates to the genetic manipulation of plants, particularly plants of the genus brassica. Methods are provided for producing transgenic brassica plants involving the introduction of a dna construct by microprojectile bombardment into pre-incubated microspores, microspore-derived embryos and microspore-derived hypocotyls.

Spore surface displays of bioactive molecules

This invention discloses novel bacterial spore systems. Genetically modified or genetically engineered viable spore systems expressing bioactive polypeptides, for example bacteriocins and/or enzymatically active feed enzymes, at the spore surface, have a great potential use in animal feeding.

High resolution characterization of biological matrices

The invention provides for a method for distinguishing spore preparation procedures using spore molecular signatures, the method comprising harvesting spores from a sample; extracting molecules from the spores, fractionating the extracted molecules for analysis; generating molecular signatures from the fractionated molecules, and comparing the molecular signatures to a library of molecular signatures.. .

Media compositions for promoting bacterial and fungal growth

Methods and compositions for enhancing or promoting germination of bacterial spores, and yeasts are disclosed herein. The composition of the present invention comprises an extract obtained from banana or any member belonging to the genus musa that may be used alone or in a growth medium to promote and enhance germination of bacterial spores, growth of bacterial, yeast, and fungal cell cultures..

Materials and methods for controlling nematodes with pasteuria spores in seed coatings

The subject invention provides novel and advantageous materials and methods for controlling phytopathogenic and/or soil-dwelling nematodes by attaching an effective amount of pasteuria spores to a seed and delivering the seeds to the situs of nematodes.. .

Fusion proteins and methods for stimulating plant growth, protecting plants from pathogens, and immobilizing bacillus spores on plant roots

The present invention is generally directed to fusion proteins containing a targeting sequence that targets the fusion protein to the exosporium of a bacillus cereus family member. The invention also relates to recombinant bacillus cereus family members expressing such fusion proteins, formulations containing the recombinant bacillus cereus family members expressing the fusion proteins.

Sterilization indicator of oxidative sterilants

A sterilization indicator for oxidative sterilants, comprising a first compartment comprising spores of one or more microorganism species, wherein the spores have been pretreated with and comprises a compound comprising a transition metal ion that is reactive with an oxidative sterilant; a second compartment comprising a growth medium and adapted to combine contents of the first compartment with contents of the second compartment for incubation after the sterilization indicator has been exposed to an oxidative sterilant; and an agent disposed in the growth medium and selected to indicate viability of the spores after the sterilization indicator has been exposed to the oxidative sterilant.. .

Coupled enzyme-based electronic monitoring of biological indicator

A sterilization indicator system and method of using the system to determine efficacy of a sterilization process. The system includes a vial having a first compartment containing spores of one or more species of microorganism; a second compartment containing a growth medium with a disaccharide, an oligosaccharide or a polysaccharide in which the vial is free of monosaccharide; an enzyme, capable of acting upon the monosaccharide to yield reaction products and electron transfer, disposed on two or more electrodes adapted to carry an electrical signal resulting from the electron transfer, the pair of electrodes positioned to contact the combined contents of the first compartment and the second compartment during incubation; and an apparatus linked or linkable to the electrodes and adapted to detect and measure the electrical signal resulting from electron transfer when the enzyme acts upon the monosaccharide..

Wastewater treatment system and related method

A system for treating a fluid in a container. The system includes an included airlift tube and active air input into the tube.

Non-enzyme based detection electronic monitoring of biological indicator

A sterilization indicator system and method of using the system to determine efficacy of a sterilization process. The system may include a vial having an optional first compartment and a second compartment comprising a growth medium comprising one or more of a disaccharide, an oligosaccharide or a polysaccharide capable of conversion to a monosaccharide by germinating spores of the one or more species of microorganism, the vial being free of the monosaccharide prior to use; a strip including two or more electrodes to oxidize the monosaccharide and to carry a resulting electrical signal, and an apparatus to detect and measure the electrical signal resulting from the oxidation.

Microcapsules and concrete containing the same

Microcapsules, for inclusion in concrete, adapted to reduce the area of a defect by at least 45% in said concrete once a quantity of said microcapsules has ruptured, said microcapsules each comprising: a polymeric shell encapsulating a liquid core, wherein the polymeric shell comprises a substantially impermeable polymer layer and the liquid core comprises carbonatogenic bacterial spores, and optionally bacterial nutrients, dispersed in a liquid medium. Also disclosed is a concrete composition comprising a quantity of such microcapsules, and a method of reducing the area of a defect in concrete..

New compositions

Acidic aqueous compositions for elimination of spores of spore forming bacteria comprise from about 100 to about 2000 ppm dissolved chlorine dioxide and a surfactant system having both a wetting effect and a spore solubilising effect.. .

Pelletized fertilizer and manufacturing the same

A method for manufacturing pelletized fertilizer includes the following steps of: mixing a biodegradable material and a water-soluble polymer material to form a first mixture; mixing a polyol, water and a nutrient salt to form a second mixture; mixing the first mixture and the second mixture to form a conglomerating gathered third mixture, and stirring the conglomerating gathered third mixture to form small lumps of the third mixture; spraying probiotic endo spores on the small lumps of the third mixture to form a plurality of fertilizer blocks; heating the fertilizer blocks, and extruding the fertilizer blocks to form a fertilizer strip; and cutting the fertilizer strip to form a plurality of pelletized fertilizer.. .

Biological indicator with integral package

A biological indicator for determining the effectiveness of a sterilization process is disclosed having a package and carrier integral therewith. The package includes a first sheet and a second sheet having a bottom portion, side portions and a top portion.

Method and sterilizing and disinfecting air and surfaces and protecting a zone from external microbial contamination

This invention relates to a method, process and apparatus for disinfecting and sterilizing all types of surfaces contaminated with microorganisms and toxic substances to render both inactive. Furthermore, this invention relates to both a method and apparatus for disinfecting and/or sterilizing breathable air and then using this air to protect a confined space from external contamination.

Particle of microbial fertilizer

A particle of a microbial fertilizer is provided, and includes the following components that are well-mixed: a culture solution containing probiotic endospores, an aqueous solution of polyol, a bio-degradable filler material, a bio-degradable polymer, and a nutritive substance. The particle of the microbial fertilizer extends storage time of the microbial fertilizer and maintains viability of probiotics, and thus effects of a microbial agent are successfully achieved..

Method for producing hen egg, hen egg, and feed for poultry

The object of the invention is to enable production of high quality eggs in poultry and to provide a method for improving productivity thereof. The invention provides a method for producing a hen egg having improved quality and productivity, the method characterized in comprising a step for feeding a hen on supplemented feed obtained by adding to poultry feed an immunostimulating substance produced by cytolysis that accompanies sporulation of mre symbiotic bacteria and/or on supplemented drinking water obtained by adding the immunostimulating substance to drinking water, wherein the immunostimulating substance is obtained by culturing the mre symbiotic bacteria, leaving the resulting culture fluid in a depleted state to thereby cause the symbiotic bacteria to convert to endospores, and removing impurities including the endosporic symbiotic bacteria from the culture fluid..

Method of producing natural b carotene by fermentation and use thereof

The present invention provides a method for producing and purifying β-carotene by blakeslea trispora fermentation and use thereof. The method comprises the following steps: a) separately inoculating the blakeslea trispora strains onto a pda culture medium so as to obtain a spore suspension; b) propagating spores in a seeding tank so as to obtain seeds for fermentation; c) inoculating the seeds for fermentation onto a fermenter and fermenting said seeds; d) adjusting the fermentation liquid to be basic by using an organic or inorganic base, and filtering so as to obtain wet mycelia; e) treating the wet mycelia with a hydrophobic non-polar organic solvent; f) mixing the wet mycelia with an organic solvent of ester and obtaining a concentrated solution by extracting; g) adding a saturated monohydric alcohol into the concentrated solution, and filtering and crystallizing so as to obtain pure ss-carotene.

Process for the production and utilization of chlamydospore rich slurry inoculum

The process for the production of a chlamydospore rich slurry inoculum begins with a substrate colonized with a desired basidiomycete fungus capable of producing chlamydospores during vegetative growth. The colonized substrate is treated to increase the chlamydospore production and content in said spawn and thereafter combined with water at rate of at least 1:6 spawn:water to obtain a slurry inoculum.

Nanocarrier based plant transfection and transduction

The present invention provides a novel method for the transduction and/or transfection of plant cells. Cell-penetrating peptides (cpps) have been successfully employed as nanocarriers to deliver proteins and oligonucleotides to single plant cell microspores as well as multi-cellular zygotic embryos.

Production of a catalytically active, metallized reactive foam material and use thereof

The invention relates to a catalytic material which is used as an optofluidic reactor, and also a method for production thereof. In this case, first a reticulated plastic foam can be fabricated which then is coated with at least one first metal or metal alloy layer.

Method for detecting the genus of bacillus in samples from oil reservoirs

The invention provides a quick method for detecting the genus of bacillus in samples from oil reservoirs, which comprise: collecting samples from oil reservoirs; inactivating microbes except for spore-forming bacillus in the samples through high temperature; collecting spores from the samples; incubating the collected spores in a medium, and stimulating to resurrect bacillus under in situ temperatures of the oil reservoirs; etecting the resurrected bacillus in the cultures using molecular biological techniques. The present invention provides an effective method to detect the genus of bacillus in samples from oil reservoirs, which is conducive to the discovery of the functional bacillus for microbial enhanced oil recovery (meor) and to revealing the ecosystem of bacillus in oil reservoirs..

Pathogenic bacteria

The invention provides novel surface coat proteins of clostridium spp. Spores, and nucleic acids encoding such proteins.

Method and producing a high level of disinfection in air and surfaces

This specification relates to an improved method, process and apparatus for disinfecting and sterilizing all types of surfaces and indoor air and room air contaminated with microorganisms. The improved apparatus consists of a multi-wavelength narrow spectral width uv source that is more effective than mercury based 254 nm germicidal lamps for destroying the dna and outer shell or membrane of virus, bacteria, spores and cists..

Container with a collapsible receptacle and a disinfectant composition

A container has: a) a collapsible receptacle, the wall of which is designed flexibly such that the internal volume of the receptacle is adapted to the volume of a liquid contained therein, and which has an outlet with an outlet valve; and b) in the receptacle a disinfectant composition in the form of a solution with a content of aliphatic alcohol of at most 20% by weight. It is possible that the disinfectant composition is not contaminated with spores or other germs also after the container has been opened, even upon repeated discharge from the container..

Apparatus and sewage sludge treatment and advanced sewage treatment

A sludge treatment apparatus includes an aeration tank serving to degrade microorganisms other than bacillus sp. In sludge to produce organic matter to thereby activate bacillus sp.; a poor aeration tank serving to reduce the activity of microorganisms in the sludge; a spore-forming tank operated under oxygen-free conditions and serving to induce the degradation and death of microorganisms remaining in the sludge while inducing the formation of spores of bacillus sp.; a bacillus sp.-activating reactor provided in an internal return line extending from the spore-forming tank to the aeration tank and serving to supply minerals to the sludge returned from the spore-forming tank to activate spore-type bacillus sp.; and a sedimentation tank serving to induce the gravity sedimentation of the sludge discharged from the spore-forming tank to separate the discharged sludge into a supernatant and a concentrated sludge..

Immunomodulation using spores and pollen grains

The present invention includes compositions, methods of making and using the compositions for modulating the immune response in a subject by providing a vaccine composition having a pollen/spore disposed in a pharmaceutical carrier for delivery to a subject, wherein the pollen/spore comprises multiple pores that connect an outer surface of the pollen/spore to an inner cavity and one or more antigens disposed on the outer surface, in the inner cavity, in the multiple pores, or a combination thereof, wherein the one or more antigens modulate an immune responses in the subject.. .

Solutions and methods of making solutions to kill or deactivate spores, microorganisms, bacteria and fungus

Exemplary embodiments of solutions of plasma activated water and peroxyacetic acid are disclosed herein. In addition, exemplary embodiments of methods for making solutions are disclosed herein.

Method of inhibiting clostridium difficile by administration of oritavancin

Glycopeptide antibiotics, such as oritavancin, demonstrate significant activity against both a vegetative form of c. Difficile and c.

Methods for bacillus spore preparation

A preparation method for strains of bacillus including bacillus anthracis, bacillus anthracis v770-npi-r, and bacillus thuringiensis using an aerated media of a protein-rich sporulation broth inoculated with a live bacillus strain. The inoculated protein-based sporulation broth is incubated, centrifuged and washed to isolate high-purity spores..

Method for detection or identification of bacteria or bacterial spores

A method and apparatus for detecting bacteria and bacterial spores are disclosed in which a sample is assessed for the presence of bacteria and/or bacterial spores by reference to horizontally polarized fluorescent light.. .

Terahertz spectroscopy characterization with high spectral and spatial resolution for biological and chemical sensing and use

Biological cells or spores are analyzed by using enhanced thz coupling to molecules by depositing a test material in a channel of a microfluidic chip using near field sensing of sub-thz radiation from the molecules. The thz radiation is enhanced by transmitting thz radiation through slots in the chip, illuminating molecules of the test material with the enhanced thz radiation transmitted through the slots.

Method for raising plants and composition used therefor

To provide a method for raising plants that have great vitality and that are strongly resistant to pests and can successfully compete against weeds. The invention provides a method for raising plants with enhanced immunity and biological activity to external and internal stresses.

Materials and methods for controlling nematodes with pasteuria spores in seed coatings

The subject invention provides novel and advantageous materials and methods for controlling phytopathogenic and/or soil-dwelling nematodes by attaching an effective amount of pasteuria spores to a seed and delivering the seeds to the situs of nematodes.. .

Biocontrol formulation containing streptomyces spp., preparing the formulation and relevant use

The present invention is a method for preparing a biocontrol formulation by the following steps. A streptomyces bacterium is selected simultaneously with superior sporulation ability, chitinase activity and antagonistic effectiveness against plant fungal pathogens by culturing with fungal pathogens, wherein the selected streptomyces bacterium is cultured on a chitin-limited plate to assess the ability of sporulation and chitinase activity, and the streptomyces bacterium with superior sporulation ability is the strain with producing powder-like and maturity form spore chains.

Bacillus isolates and methods of their use to protect against plant pathogens and virus transmission

Methods of inducing systemic acquired resistance to infection in a plant are provided. The methods comprise applying a composition comprising a bacillus control agent to said plant wherein said plant is capable of producing defense proteins.

Dictyostelid amoeba and biocontrol uses thereof

The present invention relates to dictyostelids myxamoebae of phylum mycetozoa and uses thereof. In particular, the present invention relates to the use of amoebae, slugs, or their environmentally stable spores to treat microbial infections and other uses..

Photocatalytic air treatment system and method

A photocatalytic air treatment system, including apparatuses and methods, for killing and/or mineralizing bacteria, viruses, mold, fungi, spores, mycotoxins, allergens, and other similar microorganisms or agents, and for oxidizing volatile organic compounds (vocs). The system comprises one or more reactor beds configured in one or more stages with each reactor bed including a plurality of photocatalyst coated media substantially surrounding a plurality of sheathed ultraviolet light sources that may be arranged in a plurality of configurations.

Disinfecting and antimicrobial compositions

Broad spectrum disinfecting and microbicidal compositions of biodegradable and environmentally friendly compositions containing esters formed from fatty organic alcohols and fatty carboxylic acids. These compositions display activities against the most resistant microbial forms including bacterial spores.

Therapeutic amoeba and uses thereof

The present invention relates to amoebae (slime molds) and uses thereof. In particular, the present invention relates to the use of amoebae or their environmentally stable spores to treat microbial infections and other uses..





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