|| List of recent Spectrometer-related patents
|Mass spectrometer and method of driving ion guide|
A method of operating an electrode changeover switch which switches the connection state of electrodes, the electrode changeover switch is provided in the wiring path between eight electrodes through, arranged rotation-symmetrically about ion optical axis, and voltage generation switch which generates square wave high voltage ±v. When switch is switched as shown in the drawing, two circumferentially adjacent rod electrodes are connected to form one set, a square wave voltage of opposite phase is applied to circumferentially adjacent sets, and an effectively quadrupole electric field is formed.
|Imaging mass spectrometer and a method of mass spectrometry|
An imaging mass spectrometer comprising an energy source adapted to substantially simultaneously provide energy to multiple spots on a sample to produce ions from the sample by a desorption process; and an analyser adapted to detect the arrival time and spot origin of ions resulting from said desorption process.. .
|Analyser arrangement for particle spectrometer|
The present invention relates to a method for determining at least one parameter related to charged particles emitted from a particle emitting sample. The method comprises guiding a beam of charged particles into an entrance of a measurement region by means of a lens system, and detecting positions of the particles indicative of said at least one parameter within the measurement region.
|Methods for predictive automatic gain control for hybrid mass spectrometers|
A method for mass analyzing ions comprising a restricted range mass-to-charge (m/z) ratios comprising (i) performing a survey mass analysis, using a first mass analyzer employing indirect detection of ions by image current detection, to measure a flux of ions having m/z ratios within said range and (ii) performing a dependent mass analysis, using a second mass analyzer, of an optimal quantity of ions having m/z ratios within said range, said optimal quantity collected for a time period determined by the measured ion flux, the method characterized in that: the time period is determined using a corrected ion flux that includes a correction that comprises an estimate of the quantity of ions that are undetected by the first mass analyzer.. .
|System and method for quantifying uncertainty of predicted petroleum fluid properties|
A system includes a downhole formation fluid sampling tool. The system also includes an optical spectrometer of the downhole formation fluid sampling tool and a processor.
|System and method for estimating oil formation volume factor downhole|
A system includes a downhole formation fluid sampling tool and a processor. An optical spectrometer of the downhole formation fluid sampling tool is able to measure an optical characteristic of a formation fluid flowing through the downhole formation fluid sampling tool over a plurality of wavelengths.
|Windowing combined with ion-ion reactions for chemical noise elimination|
In a first location of a mass spectrometer, a plurality of ionized molecules of an ion source are selected that have mass-to-charge ratios within a mass-to-charge ratio window width. The plurality of selected ionized molecules are transmitted from a first to a second location.
|Portable hyperspectral imager|
A portable hyperspectral imager. The imager is modular and may include a hyperspectral camera and a removably-coupled mobile display module.
|Gas diffuser ion inlet|
In some embodiments, a gas diffuser for use in a mass spectrometer is disclosed that can provide a controlled expansion of an ion-containing gas so as to reduce gas velocity for entry into subsequent stages of the mass spectrometer, e.g., a mass analyzer. In some embodiments, the controlled expansion of the gas is provided by flowing the gas through a channel whose cross-sectional area change, e.g.
|Creating an ion-ion reaction region within a low-pressure linear ion trap|
Methods and systems for creating a region for ion-ion reactions within a mass spectrometer are described. In various aspects, the methods and systems can confine a first group of ions in a sub-volume of a multipole ion trap, and introduce a second group of oppositely-charged ions into the multipole ion trap while maintaining the first group of ions within the sub-volume.
|Strategic dynamic range control for time-of-flight mass spectrometry|
A mass spectrometer of the type useful in mass cytometry includes an ion detector. A digitizing system for converting analog signals from the ion detector includes two analog-to-digital converters.
|Laser spectrometer and a method for operating a laser spectrometer|
A method for operating a laser spectrometer includes passing light of a semiconductor laser through a gas mixture containing a gas component and through an etalon structure onto a detector. The method also includes varying an injection current of the laser based on a predefined current-time function in order to tune the wavelength of the laser in a tuning range using a specific absorption line of the gas component.
|Coupled cavity spectrometer with enhanced sensitivity and dynamic range|
An optical resonator by which reflectivity of ring-down cavity mirrors can be altered and enhanced by adding external optical cavities that recycle light to the main cavity. A coupled-cavity ring-down spectroscopy (cc-rds) is used for controlling the finesse of an optical resonator.
|Ac gate ion filter method and apparatus|
The present invention uses an ac voltage instead of dc voltage on an ion gate to filter/selectively pass ions. The ions that pass through the ac ion gate can be further separated in a spectrometric instrument.
A method of operating a gas-filled collision cell in a mass spectrometer is provided. The collision cell has a longitudinal axis.
|Mass spectrometer with beam expander|
A mass spectrometer is disclosed comprising a rf confinement device, a beam expander and a time of flight mass analyser. The beam expander is arranged to expand an ion beam emerging from the rf confinement device so that the ion beam is expanded to a diameter of at least 3 mm in the orthogonal acceleration extraction region of the time of flight mass analyser..
|Method and a mass spectrometer and uses thereof for detecting ions or subsequently-ionised neutral particles from samples|
A method is used in a time-of-flight mass spectrometer for analysis of a first pulsed ion beam, the ions of which are disposed along the pulse direction, separated with respect to their ion masses. The ions of at least one individual predetermined ion mass or of at least one predetermined range of ion masses can be decoupled from the first pulsed ion beam, as at least one decoupled ion beam, and the first ion beam and the at least one decoupled ion beam are analyzed..
|High-energy ion implanter|
A high-energy ion implanter includes: a beam generation unit that includes an ion source and a mass spectrometer; a radio frequency multi-stage linear acceleration unit; a deflection unit that includes a magnetic field type energy analysis device for filtering ions by a momentum; a beam transportation line unit; and a substrate processing/supplying unit. In this apparatus, an electric field type final energy filter that deflects a high-energy scan beam in the vertical direction by an electric field is inserted between the electric field type beam collimator and the wafer in addition to the magnetic field type mass spectrometer and the magnetic field type energy analysis device as momentum filters and the radio frequency multi-stage linear acceleration unit as a velocity filter..
|Method for the laser spectroscopy of gases|
A method of determining a concentration of a gas in a sample and/or the composition of a gas using a spectrometer comprises the transmitting of radiation whose wavelength substantially continuously runs through a wavelength range, wherein the continuous running through of the wavelength range is overlaid by a wavelength modulation; the measuring of an absorption signal from the absorption of the radiation by the gas as a function of the wavelength of the radiation; the converting of the absorption signal into a first and a second derivative signal; the deriving of a first measured gas concentration value from the first derivative signal and of a second measured gas concentration value from the second derivative signal; and the determining of the concentration and/or the composition of the gas from at least the first measured gas concentration value, wherein the wavelength modulation is adapted in response to a change of a state variable of the gas such that a ratio between the first measured gas concentration value and the second measured gas concentration value is kept substantially constant.. .
|Apparatus and method for mobile device camera testing|
A mobile device testing system with a sphere assembly is disclosed. The sphere assembly is a source integrating sphere and a test integrating sphere connected by an optical channel.
|Medication assurance system and method|
A medication assurance system for verification of both the medication and the patient is disclosed. A portable spectrometer is used to obtain a light spectrum of the medication.
A mass spectrometer including chromatogram creation means for creating a chromatogram showing changes over time in an ion intensity within a predetermined mass range based on the ms analysis results, and timing determination means for determining a timing to perform ms/ms analysis based on the chromatogram. The timing determination means determines, as a timing to perform ms/ms analysis, a point in time at which a signal intensity in the chromatogram reaches a predetermined upper limit after exceeding a predetermined lower limit or a point in time at which a signal intensity in the chromatogram reaches a top of a peak without reaching the upper limit after exceeding the lower limit.
|High resolution time-of-flight mass spectrometer|
Mass spectrometers and related methods of making and using the same are disclosed herein that generally involve positioning a blocking or masking element in the path of an ion beam passing through the mass spectrometer so as to selectively block at least a portion of the ions in the ion beam from entering an accelerator. Mass spectrometers and related methods are also disclosed in which an ion beam passing through the mass spectrometer is deflected or otherwise aimed so as to approach a tof axis of an accelerator at a non-zero angle..
|Mass spectrometer vacuum interface method and apparatus|
A method of operating a mass spectrometer vacuum interface comprising a skimmer apparatus having a skimmer aperture and downstream ion extraction optics. An expanding plasma is skimmed through the skimmer aperture.
|Systems, devices, and methods for sample analysis using mass spectrometry|
A mass spectrometry system for screening a sample for one or more analytes includes a pre-mass spectrometry screening apparatus configured to pre-screen an ionized sample to generate output correlated to the composition of the sample, and a mass spectrometer. A sample gate is opened to allow flow of at least a portion of the ionized sample to the mass spectrometer and closed to prevent flow of the ionized sample to the mass spectrometer.
|Method of compensating frequency drift in an interferometer|
A method of compensating for frequency drift of a reference energy source in an ft interferometer based spectrometer instrument, the method further comprising comparing in an arithmetic unit data representing a reference interferogram and data representing a target interferogram to determining a phase shift between the interferograms in a window w in at least one region away from center-burst and generating in the arithmetic unit a mathematical transform dependent on the determined shift or shifts to be subsequently applied to control the operation of the spectrometer instrument in order to generate data representing a frequency stabilized interferogram of an unknown sample recorded by the ft interferometer.. .
|Identification of related peptides for mass spectrometry processing|
A method of identifying a related peak set from ms1 spectra data is provided. An intensity peak is selected from ms1 spectra data generated for a sample by a tandem mass spectrometer.
|Method of determining catalytic fines in an oil|
The system comprises a nmr spectrometer, a digital memory storing a calibration map comprising calibrating data for calibrating nmr spectra obtained by the nmr spectrometer and a computer programmed to analyze the nmr spectra obtained by the nmr spectrometer using calibration map and performing at least one quantitative and/or qualitative catalytic fines determination.. .
|Ionization at intermediate pressure for atmospheric pressure ionization mass spectrometers|
An ion source able to ionize liquid and gaseous effluents from interfaced liquid or gaseous separation techniques and from direct introduction of the analyte to the entrance of the ionization region. The liquid effluents from sources such as a liquid chromatograph are ionized by inlet ionization methods and the gaseous effluents from sources such as a gas chromatograph are ionized by a corona or townsend electrical discharge, or an alpha or beta emitter, or by inlet ionization, or by photoionization.
|Mass spectrometer arranged to perform ms/ms/ms|
A mass spectrometer is disclosed comprising an on trap and a fragmentation device. Ions are fragmented in the on trap to form first generation fragment ions.
|Use of windowed mass spectrometry data for retention time determination or confirmation|
A scan of a separating sample is received by a mass spectrometer at each interval of a plurality of intervals. The spectrometer performs at each interval one or more mass spectrometry scans.
|Apparatus and method relating to an improved mass spectrometer|
The present disclosure provides a mass spectrometer including means for producing a primary beam of ions for bombarding a sample under vacuum and a detector for detecting a secondary beam of ions released from the sample. The primary beam of ions includes a gaseous mixture of a cluster forming gas and one or more hydrogen-rich hydrocarbons..
|Mass spectrometer vacuum interface method and apparatus|
A method of preparing or operating a mass spectrometer vacuum interface comprising a skimmer apparatus having a skimmer aperture and an internal surface of the skimmer apparatus, comprising disposing an adsorbent or getter material on the internal surface. The internal surface has a deposition region where matter from plasma flows may be deposited and the material is disposed on part or all of the deposition region.
|Mechanism for movement of a mirror in an interferometer, an interferometer incorporating the same and a fourier transform spectrometer incorporating the same|
A mechanism that allows for precise motion of the optics of an interferometer is comprised by two or more diaphragm flexures having high lateral stiffness, creating a superior performing michelson interferometer. When coupled with precise precision control of a mirror surface and a reference laser, the above creates a superior performing fourier transform spectrometer..
After a first injection of a sample, amount of change between a highest intensity and each of two ion intensities before and after a voltage showing the highest intensity is calculated for each ce voltage. If the change is equal to or less than a threshold the ce voltage showing the highest intensity in the coarse control mode is selected as the optimal value, without performing a measurement in a fine control mode.
|Atmospheric pressure ion source for mass spectrometry|
A multiple function atmospheric pressure ion source interfaced to a mass spectrometer comprises multiple liquid inlet probes configured such that the sprays from two or more probes intersect in a mixing region gas phase sample ions or neutral species generated in the spray of one probe can react with reagent gas ions generated from one or more other probes by such ionization methods as electrospray, photoionization, corona discharge and glow discharge ionization. Reagent ions may be optimally selected to promote such processes as atmospheric pressure chemical ionization of neutral sample molecules, or charge reduction or electron transfer dissociation of multiply charged sample ions.
|High duty cycle ion spectrometer|
An ion spectrometer is provided, comprising: an ion source, arranged to generate ions continuously with a first range of mass to charge ratios; and an ion trap, arranged to receive ions from the ion source along an axis, and to eject ions with a second range of mass to charge ratios orthogonally to that axis, the second range of mass to charge ratios being narrower than the first range of mass to charge ratios. In some embodiments, ions generated by the ion source continuously flow into the ion trap.
A mass spectrometer is disclosed wherein an ion signal is split into a first and second signal. The first and second signals are multiplied by different gains and are digitised.
|Methods, apparatus, and system for mass spectrometry|
A miniature, low cost mass spectrometer capable of unit resolution over a mass range of 10 to 50 amu. The mass spectrometer incorporates several features that enhance the performance of the design over comparable instruments.
|Diathermy knife ionisation source|
A method of detecting one or more compounds, chemicals or contaminants in a substrate by mass spectrometry is disclosed. A non-living substrate is analysed by contacting the substrate with a diathermy knife.
A mass spectrometer is disclosed comprising an electron transfer dissociation cell. Positive analyte ions are fragmented into fragment ions upon colliding with singly charged negative reagent ions with the cell.
|Low-cost spectrometry system for end-user food analysis|
A compact spectrometer is disclosed that is suitable for use in mobile devices such as cellular telephones. In preferred embodiments, the spectrometer comprises a filter, at least one fourier transform focusing element, a micro-lens array, and a detector, but does not use any dispersive elements.
|Cavity enhanced absorption spectroscopy with a laser modulation side-band frequency locked to the cavity|
A cavity enhanced absorption spectrometer (ceas) and method for controlling the same. The ceas includes a coherent electro-magnetic radiation source, an electro-magnetic modulator that creates a sideband with an adjustable frequency that is offset from the radiation source frequency by imparting an adjustable frequency modulation to the radiation.
|Snapshot spectral domain optical coherence tomographer|
Provided is a snapshot spectral domain optical coherence tomographer comprising: a light source providing a plurality of beamlets; a beam splitter, splitting the plurality of beamlets into a reference arm and a sample arm; a first optical system that projects the sample arm onto multiple locations of a sample; a second optical system for collection of a plurality of reflected sample beamlets; a third optical system projecting the reference arm to a reflecting surface and receiving a plurality of reflected reference beamlets; a parallel interferometer that provides a plurality of interferograms from each of the plurality of sample beamlets with each of the plurality of reference beamlets; an optical image mapper configured to spatially separate the plurality of interferograms; a spectrometer configured to disperse each of the interferograms into its respective spectral components and project each interferogram in parallel; and a photodetector providing photon quantification.. .