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Specificity

Specificity-related patent applications - as published by the U.S. Patent and Trademark Office (USPTO).


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Detection of bacterial (mollicutes) contamination
Roche Diagnostics Operations, Inc.
October 12, 2017 - N°20170292148

The present disclosure provides a method and system for the pcr amplification of a target sequence which suppresses non-specific amplification products. The disclosure concerns the use of a primer pair optimized to amplify a nucleic acid of a contaminant in the background of genomic dna of a first organism. When dna from a second organism suspected for comprising the contaminant ...
Methods and compositions related to thioesterase enzymes
Reg Life Sciences, Llc
October 12, 2017 - N°20170292121

The present invention relates to novel mutant thioesterase enzymes and naturally-occurring equivalents thereof, compositions made from such enzymes and uses of thioesterase enzymes. In particular, the present invention provides mutant thioesterase enzymes that have altered properties, for example, altered substrate specificity, altered activity, altered selectivity, and/or altered proportional yields in the product mixtures. The present invention also provides polynucleotides ...
Composition for the treatment of burns, diabetic wounds, other types of wounds and subsequently greatly ...
Issar Pharmaceutical
October 12, 2017 - N°20170290770

Antimicrobial peptides represent a relatively new discovery in the immune system pathway. Recent designs of synthetically engineered antimicrobial peptides have demonstrated increased potency and efficacy/tolerability, enhanced specificity, and reduced toxicity in comparison. One such peptide, xylentra, has shown/demonstrated significant promise from significant in vitro studies against a large number of pathogens. Additionally, extensive animal studies have shown that ...
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Specificity Patent Applications
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  • 262+ full patent PDF documents of Specificity-related inventions.
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Methods for the detection of cyanide based on displacement of the glutathione ligand of glutathionylcobalamin ...
Research Cooperation Foundation Of Yeungnam University
October 05, 2017 - N°20170285014

Provided is a method for the detection of cyanide based on displacement of the glutathione ligand of glutathionylcobalamin by cyanide. The composition for detecting cyanide (cn−) including glutathionylcobalamin (gscbl) and a buffer has specificity in which gscbl does not react with other anions by nucleophilic substitution, but selectively reacts with only cn− by displacement. Further, the gsh bound ...
Method and reagents for detecting water contamination
Dow Global Technologies Llc
October 05, 2017 - N°20170283861

A method of examining a water supply for microbial contamination involves contacting a water supply with a novel reagent having high specificity for a legionella microbial species, wherein said reagent does not cross-react, or minimally cross-reacts, with a microbial species other than legionella. The method further involves detecting, or measuring, a contaminating concentration of a legionella species in the water ...
Protected guide rnas (pgrnas)
President And Fellows Of Harvard College
October 05, 2017 - N°20170283831

The invention provides for systems, methods, and compositions for altering expression of target gene sequences and related gene products. Provided are structural information on the cas protein of the crispr-cas system, use of this information in generating modified components of the crispr complex, vectors and vector systems which encode one or more components or modified components of a crispr complex, ...
Specificity Patent Pack
Download 262+ patent application PDFs
Specificity Patent Applications
Download 262+ Specificity-related PDFs
For professional research & prior art discovery
inventor
  • 262+ full patent PDF documents of Specificity-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
Peptide inhibitors of calcium oxalate monohydrate crystallization and uses thereof
University Of Houston
October 05, 2017 - N°20170283459

In an embodiment, the present disclosure pertains to a composition for inhibiting calcium oxalate monohydrate crystal growth comprising at least one isolated polypeptide comprising a plurality of amino acids that bind the surface of the calcium oxalate monohydrate crystal; and a plurality of amino acids spacers, wherein the amino acid spacers are arranged in varying sequences between the plurality of ...
Multiplex immuno screening assay
Institut Pasteur
September 28, 2017 - N°20170276672

The present invention provides kits and assay methods for the early detection of pathogens, precise identification of the etiologic agent, and improved disease surveillance. More specifically, the present invention discloses an immunoassay leading to the rapid and simultaneous detection of antibodies to a wide range of infectious pathogens in biological fluids of infected patients. This immunoassay involves the covalent and ...
Metabolic biomarkers for differential diagnosis of stable angina pectoris and acute coronary syndrome
Institut Pasteur
September 28, 2017 - N°20170276653

A panel of metabolic biomarkers for differential diagnosis of stable angina pectoris and acute coronary syndrome is published herein. The panel comprises one or more of the metabolic biomarkers, including malic acid, taurine, arachidonic acid, citramalic acid, methionine, pentadecanoic acid. Single use of the 6 differential metabolites provided clinically diagnostic value of sa vs. Acs with auc>0. 7. When combined, ...
Enzyme scaffolds and methods of use
Alliance For Sustainable Energy, Llc
September 28, 2017 - N°20170275653

Polypeptide scaffolds comprising enzymatic proteins are provided. The enzymatic polypeptide scaffolds comprise heterologous enzymes to form a heterologous metabolic pathway, and can be targeted to a substrate through a surface anchoring domain. The enzymatic polypeptide scaffolds leverage the high specificity and affinity protein/protein interaction between the cohesins and dockerins of microorganismal cellulosomes to form custom enzymatic arrays.
Trophoblast glycoprotein (5t4, tpbg) specific chimeric antigen receptors for cancer immunotherapy
Cellectis
September 28, 2017 - N°20170275374

The present invention relates to chimeric antigen receptors (car) that are recombinant chimeric proteins able to redirect immune cell specificity and reactivity toward selected membrane antigens, and more particularly in which extracellular ligand binding is a scfv derived from a 5t4 monoclonal antibody, conferring specific immunity against 5t4 positive cells. The engineered immune cells endowed with such cars are particularly ...
Egfrviii specific chimeric antigen receptor for cancer immunotherapy
Pfizer Inc.
September 28, 2017 - N°20170275366

The present invention relates to chimeric antigen receptors (car) that are recombinant chimeric proteins able to redirect immune cell specificity and reactivity toward selected membrane antigens, and more particularly in which extracellular ligand binding is a scfv derived from an egfrviii monoclonal antibody, conferring specific immunity against egfrviii positive cells. The tcr ko engineered immune cells endowed with such cars ...
Neutralising antibody molecules having specificity for human il-17
Ucb Biopharma Sprl
September 28, 2017 - N°20170275355

The invention relates to an antibody molecule having specificity for antigenic determinants of il-17, therapeutic uses of the antibody molecule and methods for producing said antibody molecule.
Specificity Patent Pack
Download 262+ patent application PDFs
Specificity Patent Applications
Download 262+ Specificity-related PDFs
For professional research & prior art discovery
inventor
  • 262+ full patent PDF documents of Specificity-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
Imidazoyl anilide derivatives and methods of use
Codexis, Inc.
September 28, 2017 - N°20170273978

The present invention provides kinase inhibitor analogs with improved properties, such as improved efficacy, pharmacokinetics, safety, and specificity. In some embodiments, the present invention provides nilotinib analogs that provide therapeutic benefits.
Identifying trends associated with topics from natural language text
Accenture Global Solutions Limited
September 21, 2017 - N°20170270193

A device may obtain text to be processed to identify a trend associated with a topic included in the text. The text may include a plurality of text sections, associated with the topic, that may be associated with a plurality of temporal intervals. The device may determine a respective context for the topic in each of the plurality of text ...
Peptide microarrays and novel biomarkers for celiac disease
Vibrant Holdings, Llc
September 21, 2017 - N°20170269077

The present disclosure relates generally to biomarkers and peptide arrays, and, more particularly, to a method of using a peptide array to identify biomarkers for an autoimmune disease such as, e. G., celiac disease. Furthermore, a set of novel biomarkers for celiac disease, having high sensitivity and specificity, are disclosed in addition to method of treatment using the novel biomarkers.
Plant lectins as carriers of associated drug substances into animal and human cells
Biostrategies Lc
September 21, 2017 - N°20170267987

The current invention involves the use of protein lectins produced by plants including the non-toxic carbohydrate binding subunits (b subunits) of plant “ab toxins” (ptb lectins) as delivery vehicles for mobilizing associated drug substances for delivery to animal and human cells. The resulting protein fusions or conjugates retain lectin carbohydrate specificity for binding to cells and ...
Production method for pluripotent stem cells having antigen-specific t cell receptor gene
Biostrategies Lc
September 21, 2017 - N°20170267972

(2) inducing t cell progenitors or mature t cells from the pluripotent stem cells provided in step (1). Pluripotent stem cells may preferably be ips cells. The human pluripotent stem cells bearing a t cell receptor specific for an antigen may be prepared by inducing ips cells from a t cell having the desired antigen specificity or by introducing genes encoding the ...
Antibody response phenotyping
Bloodworks
September 14, 2017 - N°20170261489

Disclosed herein are methods, systems, mediums, and kits for use in phenotyping antibody responses via devices such as surface plasmon resonance devices. Such phenotypes can include total target-specific antibody titers, quantitative isotype distribution of the target-specific antibodies, and/or epitope specificity of the target-specific antibodies. Other methods, systems, mediums, and kits are also disclosed.
Td probe and its uses
Seegene, Inc.
September 14, 2017 - N°20170260576

The present invention relates to a target discriminative probe (td probe) and its uses or applications. The td probe is hybridized with a target nucleic acid sequence through both of the 5′-second hybridization portion and the 3′-first hybridization portion. When the td probe is hybridized with a non-target nucleic acid sequence, both the 5′-second hybridization portion and ...
Chemically-locked bispecific antibodies
Sorrento Therapeutics, Inc.
September 14, 2017 - N°20170260291

There is disclosed a process for forming chemically-locked bispecific or heterodimer antibodies, preferably in the igg class, in high specificity and with high homogeneity. More specifically, there is disclosed a chemically-locked bispecific igg class antibody having a linkage region joined together with bio-orthogonal click chemistry.
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