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Skin patents

      

This page is updated frequently with new Skin-related patent applications.




new patent Image processing correcting dark circle under human eye
An image capture apparatus includes a pupil detection unit, a dark circle correction map generation unit, and an image composition unit. The image capture apparatus corrects a dark circle in an image.
Casio Computer Co., Ltd.


new patent Resolving application multitasking degradation
Systems and methods for resolving application multitasking degradation are disclosed. In aspects, a computer implemented method is used with a user device including a multitasking operating system, shared user device resources, a first application and a second application.
International Business Machines Corporation


new patent Composition for diagnosing skin damage caused by fine dust, and composition comprising galangin as active ingredient
The present specification discloses a biomarker for diagnosing skin cell damage caused by fine dust, a kit using the same, and a novel use of a composition comprising galangin as an active ingredient. Specifically, it is possible to conveniently check skin damage caused by fine dust by measuring and comparing the expression amounts of the biomarker in normal cells and cells damaged by fine dust.
Amorepacific Corporation


new patent Methods and compositions for treatment of skin disorders
The invention provides methods and compositions for the treatment of a skin disorder associated with detrimental tnfα activity, such as psoriasis. The invention includes methods for treating a skin disorder associated with detrimental tnfα activity, such as psoriasis, in a subject who has failed or lost response to prior biologic therapy, such as prior administration of etanercept.
Abbvie Biotechnology Ltd


new patent Biguanide compound and use thereof
The present invention relates to a guanidine compound and a use thereof, and more specifically, to a guanidine derivative showing excellent effects of inhibiting cancer cell proliferation, cancer metastasis, and cancer recurrence; a preparation method thereof; and a pharmaceutical composition containing the same as an active ingredient. Compared to existing drugs, the guanidine derivative according to the present invention shows excellent effects of inhibiting cancer cell proliferation, cancer metastasis, and cancer recurrence even with small doses, and may thus be effectively used in preventing or treating various cancers such as uterine cancer, breast cancer, stomach cancer, brain cancer, rectal cancer, colorectal cancer, lung cancer, skin cancer, blood cancer, liver cancer, etc., inhibiting cancer cell proliferation and cancer metastasis..
Immunomet Therapeutics Inc.


new patent Cannabis-based extracts and topical formulations for use in skin disorders
The present invention discloses a pharmaceutical topical composition comprising cannabidiol (cbd) or a derivative thereof and tetrahydrocannabinol (thc) or a derivative thereof in an about 1:1 ratio, useful for treatment or prevention of inflammatory skin disorders, and treatment methods thereof.. .
One World Cannabis Ltd


new patent Therapeutic agents for use in the propylaxis and/or treatment of hyperkinetic movement disorders
(rs)-[2-(3,4-dimethoxyphenyl)ethyl][2-hydroxy-3-(3-methylphenoxy)propyl]amine having the formula (ia), or a pharmaceutically acceptable salt thereof for the formulation of a pharmaceutical composition is useful for the prophylaxis and/or the treatment of hyperkinetic movement disorders associated with huntington's disease, wilson's disease, tourette syndrome, restless leg syndrome, and tardive dyskinesia.. .
Som Innovation Biotech, S.l.


new patent Portable device for the analysis of skin traumas and analyzing skin traumas using a portable device
A portable device for the analysis of skin traumas is disclosed, the device allowing the medical professional to evaluate and analyze the healing process of the skin traumas, providing the medical professional with the temperature parameters, distance parameters and diagnosis parameters related to the skin trauma. By using the proposed portable device, it is possible, for example, to evaluate if the dimensions of the skin trauma have changed throughout the time, and also to generate a temperature map of the skin trauma as well as a history of conducted analyses.
I-healthsys Produtos Médicos Ltda - Me


Method for providing a customized product recommendation
Included is a method for providing a customized product recommendation to a user. Information is collected from a user regarding issues experienced by the user after cutting and/or removing hair selected from the group consisting of discomfort, dry skin, missed hairs, hair not cut close enough, nicks, cuts, trapped hairs, ingrown hairs, razor bumps, blemishes, acne, razor burn, irritation, redness, pseudofolliculitis barbae, and itching.
The Gillette Company Llc


N-(4-hydroxy-4-methyl-cyclohexyl)-4-phenyl-benzenesulfonamides and n-(4- hydroxy-4-methyl-cyclohexyl)-4-(2-pyridyl)benzenesulfonamides and their therapeutic use
The present invention pertains generally to the field of therapeutic compounds. More specifically the present invention pertains to certain substituted n-(4-hydroxy-4-methyl-cyclohexyl)-4-phenyl-benzenesulfonamide and n-(4-hydroxy-4-methyl-cyclohexyl)-4-(2-pyridyl)benzenesulfonamide compounds (collectively referred to herein as hmc compounds) that are useful, for example, in the treatment of disorders (e.g., diseases) including, inflammation and/or joint destruction and/or bone loss; disorders mediated by excessive and/or inappropriate and/or prolonged activation of the immune system; inflammatory and autoimmune disorders, for example, rheumatoid arthritis; psoriasis; psoriatic arthritis; chronic obstructive pulmonary disease (copd); asthma; atherosclerosis; inflammatory bowel disease; ankylosing spondylitis; multiple sclerosis; systemic lupus erythematosus; sjogren's syndrome; a disorder associated with bone loss, such as bone loss associated with excessive osteoclast activity in rheumatoid arthritis, osteoporosis, cancer-associated bone disease, or paget's disease; cancer, such as a haematological malignancy, such as multiple myeloma, leukemia, or lymphoma, or a solid tumour cancer, such as bladder cancer, breast cancer (female and/or male), colon cancer, renal cell carcinoma, kidney cancer, lung cancer, pancreatic cancer, gastric cancer, prostate cancer, brain cancer, skin cancer, thyroid cancer, basal cell ameloblastoma, or melanoma; a disorder associated with fibrosis, such as systemic sclerosis or scleroderma; or a rare vasculitide, such as behçet's disease.
Pimco 2664 Limited


Apparatus, sensor relays facilitating the transfer of information via a movement device and output device

The present disclosure contains embodiments of an apparatus, system and method designed to facilitate learning or efficient multitasking involving movement while one or more user's or users' movement devices process or respond to different stimuli to facilitate users moving while learning, working, or participating in a simulation. In some embodiments this may be accomplished with the aid of a circular treadmill, spherical walkway, or combinable modular trackpads that may be linked to allow a user to lay the apparatus in a path suited for a plurality of environments.
Forward Entertainment & Technology, Llc

Apparatus, moving while receiving information on output devices using sensor relays

A method and apparatus to facilitate learning while moving, efficient multitasking involving movement while the user processes or responds to different stimuli. The stimuli may include but are not limited to information related to education or entertainment or feedback concerning the user's movement.
Forward Entertainment & Technology, Llc

Methods for treating aging and skin disorders using nucleic acids targeting tyr or mmp1

The present invention relates to rnai constructs with improved tissue and cellular uptake characteristics and methods of use of these compounds in dermal applications.. .
Rxi Pharmaceuticals Corporation

Allosteric modulators of nicotinic acetylcholine receptors

The present disclosure relates to compounds of formula i that are useful as modulators of α7 nachr, compositions comprising such compounds, and the use of such compounds for preventing, treating, or ameliorating disease, particularly disorders of the central nervous system such as cognitive impairments in alzheimer's disease, parkinson's disease, and schizophrenia, as well as for l-dopa induced-dyskinesia and inflammation. .
Merck Sharp & Dohme Corp.

Touch-free topical spray of halobetasol

The present invention relates to a touch-free topical spray of halobetasol comprising a composition which is delivered through a dispensing system, wherein the composition comprises from about 0.01% w/w to about 0.5% w/w of halobetasol based on the total weight of the composition for the treatment of skin disorders, wherein the dispensing system comprises a metered valve assembly comprising a metered valve having a stem connected to an actuator, wherein the actuator is provided with an insert having an orifice diameter in a range of about 0.2 mm to about 1.5 mm, and wherein no rubbing-in is required when said composition is applied to affected skin. Said topical spray compositions offer ease of application leading to enhanced patient compliance.
Sun Pharmaceutical Industries Limited

Early allergy detection, notification and management systems and methods

A watch-like early allergy detection, notification and management system is equipped with a motion detector as well as one or more physiological sensors to measure heart rate, skin color change, skin galvanic response, oxygen saturation and blood pressure to detect early symptoms of an allergic reaction. False alarms are reduced by simultaneously measuring ambient temperature and physical activity of the subject.

Immune regulatory oligonucleotide (iro) compounds to modulate toll-like receptor based immune response

The invention provides novel immune regulatory oligonucleotides (iro) as antagonist of tlrs and methods of use thereof. These iros have unique sequences that inhibit or suppress tlr-mediated signaling in response to a tlr ligand or tlr agonist.
Idera Pharmaceuticals, Inc.

Antibacterial clay compositions for use as a topical ointment

The present invention is directed to synthetic bactericidal compositions having clay like properties and a method of using these compositions to topically treat bacterially-caused skin infections and skin diseases. The compositions within the scope of the invention comprise a bactericidal effective amount of a reducing agent, such as pyrite, marcasite, pyrrhotite, fes2, fes, feso4—or other reducing agents having like properties, and a natural clay or clay mineral and/or synthetic clay or clay mineral, or other suitable materials having clay-like properties with a high (>10) or low (<5) ph.
Bishopsgate Exploration Ltd.

Cosmetic use of a peppermint extract

The invention also relates to a cosmetic care method, for maintaining or regulating renewal of the cells of the epidermis associated with a deficiency in the expression of notch proteins in keratinocyte progenitor cells, intended for mature and/or dry skin.. .

Topical compositions comprising hydroxy acids and cannabinoids for skin care

The present invention relates to compositions and methods for the prevention and treatment of skin disorders and for the rejuvenation of the skin. In particular, the application describes topical compositions and methods of treatments comprising the combined use of one or more cannabinoids and one or more hydroxy acids in a suitable carrier..
Kannalnnovations Llc

Ammonia oxidizing bacteria for treatment of eczema

A method for treating a skin disorder, e.g., acne, e.g. Acne vulgaris, in a subject is provided.
Aobiome Llc

Use of isothiocyanate functional surfactants as nrf2 inducers to treat epidermolysis bullosa simplex and related diseases

The present invention relates to methods and compositions for the prevention and treatment of keratin-based skin diseases. In particular, the application describes compositions and methods of treating a patient suffering from skin blistering comprising the use of phase ii enzyme inducers and/or activity modifiers..

Mammal and fish biopsy dart

A dart for use in gathering a tissue sample from an animal is disclosed. The dart has an adapter base for fastening to an elongated dart delivery shaft.
Tissuegrab Biopsy Systems Llc

Systems and methods for adaptive skin treatment

According to an aspect of some embodiments of the present invention there is provided a method of dynamically adapting a facial treatment based on a current facial skin profile, comprising: using at least one sensor for measuring at least one current value of at least one variable skin characteristic of facial skin of a patient; acquiring at least one personal skin characteristic of facial skin of the patient; calculating a current facial skin status of the patient according to the at least one personal skin characteristic and the at least one current value; determining instructions to operate a treatment applicator according to the current facial skin status; and instructing the treatment applicator according to the instructions.. .

Inhibitors of trka kinase

The present invention is directed to the compounds of formula i which are inhibitors of tropomyosin-related kinase a (trka): formula (i) or steroisomers, tautomers or a pharmaceutically acceptable salts, metabolites, isotopes, solvates or prodrugs thereof, wherein, ra, rb, rc, rd, r1, r2, l and het-ar are as defined herein. These compounds can be used for the preventive and/or therapeutic treatment of diseases or disorders associated with abnormal activities of nerve growth factor (ngf) receptor trka such as pain, inflammation or an inflammatory diseases, cancer, atherosclerosis, restenosis, thrombosis, neurodegenerative diseases, erectile dysfunction (ed), skin disorders, autoimmune disease like multiple sclerosis, sjögren's syndrome, endometriosis, diabetic peripheral neuropathy, prostatitis, infectious diseases, diseases related to an imbalance of the regulation of bone remodeling, endometriosis, pelvic pain syndrome and diseases resulting from abnormal tissue remodelling and fibrotic disorders; or a disease, disorder, injury, or malfunction relating to dysmyelination or demyelination..
Gvk Biosciences Private Limited

Multiaxial robot of multitasking

A multiaxial robot of multitasking includes a base, a plurality of arms, at least one wrist, a first engaging structure, and a second engaging structure. The arms are sequentially connected from the base, and any adjacent two of the base and the arms are configured to rotate relative to each other.
Inventec Appliances Corp.

Pterostilbene (pter) for use in the prevention and/or treatment of skin diseases, damages or injuries

The present invention refers to the use of pter, or any acceptable salt thereof, optionally in combination with quer, or any acceptable salt thereof, for the manufacture of pharmaceutical compositions for preventing and/or treating skin diseases, damages or injuries. Those methods of prevention and/or treatment comprise the administration of an effective amount of a composition comprising pter as active compound, or any acceptable salt thereof, optionally in combination with quer, or any acceptable salt thereof, to the subject.
Green Molecular, S.l.

Vivo treatment of skin lesions by electrical nanopulses

This disclosure relates to an in vivo treatment of a skin lesion of a mammal comprising application of electrical energy to the skin lesion in a form of electrical pulses. At least one electrical pulse is applied.
Pulse Biosciences, Inc.

A skin lightening composition comprising niacinamide and ilomastat

The present invention is in the field of personal care compositions; in particular skin lightening compositions. A composition that combines the cyclic adenylic acid reduction and the reduction of melanin content in melanocytes remains to be desired.
Conopco, Inc., D/b/a Unilever

Allergy skin test applicator

An allergy testing kit contains a plurality of allergy testing applicators, an allergy testing tray and a plurality of allergen bottles each containing an allergen. Each of the applicators contains an elongated handle, a plurality of arms extending from the elongated handle and disposed in an asymmetrical configuration, and a plurality of legs with tines extending from each of the arms.

Assessing cardiovascular function using an optical sensor

This document describes assessing cardiovascular function using an optical sensor, such as through sensing relevant hemodynamics understood by pulse transit times, blood pressures, pulse-wave velocities, and, in more breadth, ballistocardiograms and pressure-volume loops. The techniques disclosed in this document use various optical sensors to sense hemodynamics, such as skin color and skin and other organ displacement.
Google Inc.

Assessing cardiovascular function using an optical sensor

This document describes assessing cardiovascular function using an optical sensor, such as through sensing relevant hemodynamics understood by pulse transit times, blood pressures, pulse-wave velocities, and, in more breadth, ballistocardiograms and pressure-volume loops. The techniques disclosed in this document use various optical sensors to sense hemodynamics, such as skin color and skin and other organ displacement.
Google Inc.

Skin treatment device

The invention relates to a skin treatment device comprising a handle with an energy supply, an application head with at least one heat source comprising at least one semiconductor light source, and at least one heat sink comprising cooling fins. The heat sink is located remote from the heat source within the handle.
Braun Gmbh

Self-adaptive matrix completion for heart rate estimation from face videos under realistic conditions

Recent studies in computer vision have shown that, while practically invisible to a human observer, skin color changes due to blood flow can be captured on face videos and, surprisingly, be used to estimate the heart rate (hr). While considerable progress has been made in the last few years, still many issues remain open.
University Of Pittsburgh - Of The Commonwealth Of Higher Education

Systems and methods for skinning an application with interactive content

A method of skinning an application with content includes receiving, by a client device from a content provider over a data network, a replacement asset associated with a tag specifying an event type, and displaying, by a graphical user interface of the client device, an initial asset of an application executed by the client device. The method further includes determining, by a hooking component of the client device, that an event corresponding to the event type occurred during execution of the application, and selecting, by the hooking component, the replacement asset associated with the tag specifying the event type, responsive to the determination that the event corresponding to the event type occurred.
Google Inc.

Apparatus and treatment of foot and nail diseases

An apparatus for treatment of fungal infections and/or other foot skin disorders, comprises a shoe-type housing having a substantially hollow interior forming a treatment chamber, a supporting platform disposed within the hollow chamber; so that a foot of a patient positioned within the treatment chamber is supported by the platform, so that nails are disposed at the lower level of the front part of the chamber, whereas the heel of the foot is being elevated a rear part thereof. A delivery and control assembly for the aqueous solution is provided.

Skin compositions and methods of use thereof

Provided are body corrective cosmetic formulations and methods of use thereof.. .
Olivo Laboratories, Llc

Topical formulations comprising a steroid

The application provides formulations for the topical administration of an active agent comprising at least one steroid, in the form of topical sprays that are propellant-free, and/or substantially non-foaming, and/or alcohol-free. The present application also provides processes for preparing such compositions and methods of using them in management of skin diseases or disorders such as psoriasis, dermatoses, and other associated skin diseases or disorders..
Dr. Reddy's Laboratories Ltd.

Histone deacetylase inhibitors

In recognition of the need to develop novel therapeutic agents, the present invention provides novel histone deacetylase inhibitors. These compounds include an ester bond making them sensitive to deactivation by esterases.
Dana-farber Cancer Institute, Inc.

Devices, systems, and methods for moving tissue within a body

In general, devices, systems, and methods for relocating tissue during surgeries are provided. In one embodiment, a surgical apparatus is provided that includes a needle, a hook movably disposed in the needle, an actuator, and a slidable member.
Medos International Sari

Cosmetic composition for improving condition of skin, containing cell culture medium, epidermal growth factor and bovine serum albumin

The present invention relates to: a cosmetic composition for improving the condition of the skin, containing, as active ingredients, a cell culture medium, an epidermal growth factor and a bovine serum albumin; a method for improving the condition of the skin by using the same; and a method for preventing or treating skin diseases. According to the present invention, the cosmetic composition can exhibit excellent wrinkle-reducing and wound-healing effects even when only a small amount of egf is used, and thus can be useful in improving the condition of the skin or in preventing or treating skin diseases..
Biocoz Global Korea Corp.

A skin lightening composition comprising 4-hexylresorcinol and ilomastat

The present invention is in the field of personal care compositions; in particular skin lightening compositions. A more effective way to reduce melanin content in melanocytes remains to be desired.
Conopco, Inc., D/b/a Unilever

Therapeutic uses of berberine formulations

Uses of pharmaceutical compositions comprising berberine for treatment of dermatologic toxicities and other skin disorders.. .
Twi Biotechnology, Inc.

N-(4-hydroxy-4-methyl-cyclohexyl)-4-phenyl-benzenesulfonamide and n-(4-hydroxy-4-methyl-cyclohexyl)-4-(2-pyridyl)-benzenesulfonamide compounds and their therapeutic use

The present invention pertains generally to the field of therapeutic compounds. More specifically the present invention pertains to certain substituted n-(4-hydroxy-4-methyl-cyclohexyl)-4-phenyl-benzenesulfonamide and n-(4-hydroxy-4-methyl-cyclohexyl)-4-(2-pyridyl)benzenesulfonamide compounds (collectively referred to herein as hmc compounds) that are useful, for example, in the treatment of disorders (e.g., diseases) including, inflammation and/or joint destruction and/or bone loss; disorders mediated by excessive and/or inappropriate and/or prolonged activation of the immune system; inflammatory and autoimmune disorders, for example, rheumatoid arthritis; psoriasis; psoriatic arthritis; chronic obstructive pulmonary disease (copd); asthma; atherosclerosis; inflammatory bowel disease; ankylosing spondylitis; multiple sclerosis; systemic lupus erythematosus; sjogren's syndrome; a disorder associated with bone loss, such as bone loss associated with excessive osteoclast activity in rheumatoid arthritis, osteoporosis, cancer-associated bone disease, or paget's disease; cancer, such as a haematological malignancy, such as multiple myeloma, leukemia, or lymphoma, or a solid tumour cancer, such as bladder cancer, breast cancer (female and/or male), colon cancer, renal cell carcinoma, kidney cancer, lung cancer, pancreatic cancer, gastric cancer, prostate cancer, brain cancer, skin cancer, thyroid cancer, basal cell ameloblastoma, or melanoma; a disorder associated with fibrosis, such as systemic sclerosis or scleroderma; or a rare vasculitide, such as behçet's disease.
Pimco 2664 Limited

Skin treatment device

The present disclosure is concerned with a skin treatment device having at least a first led, at least a first controllable current source, in particular a first controllable constant current source, for driving the first led, a control unit for controlled switching of at least the first controllable current source between a first state in which current is provided to the first led and a second state in which no current is provided to the first led, and at least a first current sensor that is connected or connectable with the first led so that the first current sensor and the first led form a current path at least in the second state of the first controllable current source.. .
Braun Gmbh

Non-cleavable polymer conjugated with alpha v beta 3 integrin thyroid antagonists

Chemical compositions and methods of synthesis thereof. The compositions disclosed and described herein are directed toward and classified as anti-angiogenic thyrointegrin antagonists, which may be capable of reacting with one or more cell surface receptors of the integrin αvβ3 receptor family.
Nanopharmaceuticals, Llc

Medical methods and systems for skin treatment

The present invention generally relates to improved medical devices, systems, and methods, with exemplary embodiments providing improved cooling treatment probes and cooling treatment methods and systems. In some embodiments, freezing of the skin may be desirable to effect the hypopigmentation of the skin of the patient.
R2 Dermatology, Inc.

A device for enhancing and/or maintaining a penile erection

The present invention relates to a device for treatment of erectile dysfunction comprising a ring. The device further provides for retraction of the foreskin of the user and maintains the retraction of the foreskin throughout sexual activity.
Exia Biomedical Inc.

Systems, models and methods for identifying and evaluating skin-active agents effective for treating an array of skin disorders

Methods and systems for constructing a gene expression signature representative of a number of biological conditions, systems and methods for determining functional relationships between a skin-active agent and skin conditions of interest, and methods and systems for identifying skin-active agents with broad spectrum activity are provided.. .
The Procter & Gamble Company

Skin therapy apparatus with needle

A skin treatment device is provided, which includes a needle frame in which a front end outlet of a needle that penetrates an inside thereof projects toward a front thereof, a rear end inlet of the needle is open to an outside of a rear surface thereof, and a stepped partition wall is provided in a closed shape on the outside of the rear surface thereof; a needle cover having a space portion formed on a rear thereof toward an inside thereof, a needle guide portion formed on a front surface thereof; a contact pcb configured to receive a power that is supplied from a power supply device; and a needle hub having an insertion portion formed in a front thereof toward an inside thereof.. .
Eunsung Global Corp.

Nanoparticles and their use in cancer therapy

The present invention provides a nanoparticle comprising a core comprising a metal; and a corona comprising a plurality of ligands covalently linked to the core, the plurality of ligands including at least a first species of ligand comprising an ethylene glycol portion and an amine group and at least a second species of ligand comprising a carbohydrate group, for use in a method of treating a cancer, particularly skin cancer, in a mammalian subject. Also disclosed are methods of treatment by administering the nanoparticles alone or in combination with radiotherapy..
Midatech Ltd

Composition for prevention or treatment of cutaneous disorder

Wherein r1 and r2 are independently selected from the group consisting of —oh, —ch3, —cf3ch2o—, and ch3o—. Such pharmaceutical composition or medical device is notably useful for the treatment and/or prevention of a skin disorder involving excessive angiogenesis and/or fibrogenesis, such as in skin fibrosis, angiofibromas, hamartomas and periungual fibromas, skin manifestation occurring with rosacea, acne, atopic dermatitis, scleroderma, psoriasis and lupus erythematosus, and especially of tuberous sclerosis complex and skin manifestation occurring with tuberous sclerosis complex..

Cosmetic formulation to reduce facial flushing

The present invention features novel cosmetic skin care compositions for improving the appearance of flushed or rosacea-affected skin.. .
Jan Marini Skin Research

Preventing and treating inflammatory skin diseases

The present invention relates to methods of treating, preventing, reducing the severity of, reducing the incidence of, delaying the onset of, or reducing pathogenesis of an inflammatory skin disease, condition or lesion in a human subject, which include the step of administering to the subject a therapeutically effective amount of mi rna compositions. In addition, methods of this invention may be used to treat symptoms of inflammatory skin diseases and reduce and/or inhibit keratinocyte proliferation..
Tel Hashomer Medical Research Infrastructure And Services Ltd.

Systems and methods for drying skinned ceramic wares using recycled microwave radiation

Systems and methods for drying skinned ceramic wares (10) using recycled microwave radiation are disclosed. The method includes irradiating wet skinned ceramic wares (10w) in a first applicator section (124w) with microwave radiation (212), wherein said irradiating (212) gives rise to reflected microwave radiation (212r).
Corning Incorporated

Neuregulin in the treatment of fibrotic disorders

The present invention relates to the treatment of fibrotic disorders. More particularly, the present invention relates to the use of a neuregulin protein in a method treating, preventing and/or delaying fibrotic skin disorders, fibrotic lung disorders or liver cirrhosis..
Universiteit Antwerpen

Decubitus treatment system

The present invention includes compositions and methods for cleaning, treating, protection and resolution of decubitus ulcers comprising: a first composition comprising a wound cleaning solution comprising aloe vera gel comprising at least 5,000 mps, a balanced salt solution; and a second composition comprising a wound healing gel comprising aloe vera gel comprising at least 10,000 mps, a thickening agent, and one or more preservatives and, optionally, a third composition comprising a moisture barrier cream comprising a vegetable-based emulsifier, a cosmetic ester for dry skin that has low occlusivity, an ester-based emollient that is oxidation stable and has low occlusivity; a beeswax; a hydrogenated oil, glycerin, a buffering agent, aloe vera gel comprising at least 2,000 mps and water.. .
Aloe Bioscience, Llc

Formulations containing pomegranate seed oil, rosa canina fruit oil and inula viscosa oleoresin or extract

The invention relates, in general, to healing formulations containing pomegranate seed oil, rosa canina fruit oil, and inula viscosa oleoresin or extract. In some instances the formulations may also contain citrus medica vulgaris etrog oil or extract and other ingredients.
Pomega, Inc.

Apparatus and skin treatment

A dermatological skin treatment device is provided. The device comprises a handpiece and a cutting tool, wherein the tool is inserted through the conduit and percutaneously inserted into a tissue disposed within a recessed area of the handpiece.
Ulthera, Inc.

Methods of treating skin cancer by administering a pd-1 inhibitor

The present invention provides methods for treating, reducing the severity, or inhibiting the growth of cancer (e.g., skin cancer). The methods of the present invention comprise administering to a subject in need thereof a therapeutically effective amount of a programmed death 1 (pd-1) antagonist (e.g., an anti-pd-1 antibody).
Regeneron Pharmaceuticals, Inc.

Methods and systems for trans-tissue substance delivery using plasmaporation

Exemplary systems and methods associated with trans-tissue substance delivery using non-thermal plasma to porate skin or tissues using contoured dielectrics/electrodes and grounding techniques. In some embodiments, a substance delivery system may be incorporated into the plasma generating device for automatically controlled skin treatments.
Ep Technologies Llc

Pharmaceutical formulations for treating skin disorders and methods for fabricating and using thereof

Pharmaceutical compositions for treating, mitigating or preventing inflammatory skin diseases, disorders and/or pathologies are described, the compositions comprising a tetracycline-class antibiotic(s), omega fatty acid(s), and/or nicotinic acid or derivatives thereof. Methods for fabricating the compositions and using them are also described..
Imprimis Pharmaceuticals, Inc.

Methods of use to orally and topically treat acne and other skin conditions by administering a 19-nor containing vitamin d analog with or without a retinoid

Oral and topical pharmaceutical compositions, kits and methods of treatment thereof for treating various skin disorder including acne, psoriasis, ichthyosis, photoaging, photodamaged skin, and, skin cancer. Exemplary vitamin d analogs as active pharmaceutical ingredients include 2-methylene-19-nor-20(s)-1α-hydroxy-bishomopregnacalciferol, 19-nor-26,27-dimethylene-20(s)-2-methylene-1α,25-dihydroxyvitamin d3, 2-methylene-1α,25-dihydroxy-(17e)-17(20)-dehydro-19-nor-vitamin d3, 2-methylene-19-nor-(24r)-1α,25-dihydroxyvitamin d2, 2-methylene-(20r,25s)-19,26-dinor-1α,25-dihydroxyvitamin d3, 2-methylene-19-nor-1α-hydroxy-pregnacalciferol, 1α-hydroxy-2-methylene-19-nor-homopregnacalciferol, (20r)-1α-hydroxy-2-methylene-19-nor-bishomopregnacalciferol, 2-methylene-19-nor-(20s)-1α-hydroxy-trishomopregnacalciferol, 2-methylene-23,23-difluoro-1α-hydroxy-19-nor-bishomopregnacalciferol, 2-methylene-(20s)-23,23-difluoro-1α-hydroxy-19-nor-bishomopregnancalciferol, (2-(3′hydroxypropyl-1′,2′-idene)-19,23,24-trinor-(20s)-1α-hydroxyvitamin d3, 2-methylene-18,19-dinor-(20s)-1α,25-dihydroxyvitamin d3, a stereoisomer thereof, a prodrug thereof in oral compositions, a salt thereof, and/or a solute thereof.
Wisconsin Alumni Research Foundation

Metabolites of the janus kinase inhibitor (r)-3-(4-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)-1h-pyrazol-1-yl)-3-cyclopentylpropanenitrile

The present invention provides active metablites of 3-(4-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)-1h-pyrazol-1-yl)-3-cyclopentylpropanenitrile that modulate the activity of janus kinases and are useful in the treatment of diseases related to activity of janus kinases including, for example, immune-related diseases, skin disorders, myeloid proliferative disorders, cancer, and other diseases.. .
Incyte Holdings Corporation

Composition and treatment of neuropsychiatric disorders

The present invention relates to a composition and method for combinative therapy, capable of temporarily regulating inherent dysfunctional neural processes and reducing symptoms and/or signs of neuropsychiatric disorders including, but not limited to, psychostimulant use disorder (pud) and other substance-related additive disorders, post-traumatic stress disorder (ptsd) and other trauma- and stress-related disorders, and levodopa-induced dyskinesia (lid) and other types of dyskinesias. The present specification shows specific examples of a dosage form..
Duke University

Skin treatment system

A method of operating a flashlamp in a skin treatment system comprises the steps of charging capacitor, discharging the capacitor through a flashlamp, and interrupting the discharge of the capacitor through the flashlamp at a predetermined time based on at least one condition caused by the discharge of the capacitor through the flashlamp.. .
Koninklijke Philips N.v.

Skin treatment device

A device (100a) for treating skin (s) comprises a skin treatment member, a skin contacting surface (10), a mounting member (104) for mounting the skin treatment member (110) and the skin contacting surface (107), and friction controlling means (124, 126, 134) configured and arranged to control friction between the skin contacting surface (107) and the skin (s) to be treated, in at least one controlled friction area (122) of the skin contacting surface (107), during use when the skin contacting surface (107) is moved over the skin (s). In particular, the friction controlling means (124, 126, 134) are adapted to introduce a slip motion of the controlled friction area (122) relative to the mounting member (104) in a direction corresponding to a local direction of extension of the skin contacting surface (107).
Konnklijke Philips N.v.

Systems and methods for dynamic masking of data

Embodiments disclosed herein may be useful for controlling access to data, and particularly to data intended for restricted access. In at least one embodiment, a system and method for dynamic data masking intercepts input/output (i/o) read requests for data in external memory, determines if the data to be read should be masked, and appropriately, dynamically masks data before the requested data is written into system memory.
Idera, Inc.

Method of identifying cosmetic agents for moisturizing skin

Methods of identifying potential skin moisturizing actives for the treatment of dry skin and method of formulating a moisturizing skin care composition using actives identified by the method. Moisturizing agents can be identified by comparing the transcriptional profile of a skin tissue sample contacted by a test agent to a negative or positive control to determine if the regulation of certain genes corresponds to the appropriate direction of regulation indicated by the control.
The Procter & Gamble Company

Agricultural skin grafting

A method of forming a material structure from structural units contained within a liquid solution in a spray head is described. The liquid solution includes a solvent and a solute, the solute comprising a plurality of the structural units, the structural units including monomer units, oligomer units, or combinations thereof.
Apeel Technology, Inc.

Removable tips for use with skin treatment systems

An apparatus for treating skin has a console with a user input device and a handpiece assembly. The handpiece assembly is configured to treat skin.
Edge Systems Llc

Tips for skin treatment device

An apparatus for treating skin has a console with a user input device and a handpiece assembly. The handpiece assembly is configured to treat skin.
Edge Systems Llc

Skin treatment using variable rf

A skin treatment device used for cellulite treatment, skin tightening or body contouring which combines negative pressure treatment and rf treatment, where the rf treatment uses variable frequencies during a treatment cycle.. .
Viora Ltd

Soluble, stable, anti-inflammatory, proliferative, protective and mucoadhesive pharmaceutical compositions; use thereof for treating mucositis conditions and producing same; base pharmaceutical composition for preparing the pharmaceutical compositions and producing same

The present invention relates to pharmaceutical compositions with mucoadhesive and sustained release characteristics containing the association of the extract or fractions of curcuma longa l. With curcuminoid content greater than 5% and bidens pilosa (bd) extract, which has an important proliferative and anti-inflammatory effect, for the treatment of inflammatory diseases of the oral cavity (stomatitis) and of the gastrointestinal tract, as, for example, mucositis induced by radiotherapy and/or chemotherapy and aphthous lesions.
Universidade Federal De Goias

Aldose reductase inhibitors and uses thereof

The present invention relates to novel compounds and pharmaceutical compositions thereof, and methods for promoting healthy aging of skin, the treatment of skin disorders, the treatment of cardiovascular disorders, the treatment of renal disorders, the treatment of angiogenesis disorders, such as cancer, treatment of tissue damage, such as non-cardiac tissue damage, the treatment of evolving myocardial infarction, and the treatment of various other disorders, such as complications arising from diabetes with the compounds and compositions of the invention. Other disorders can include, but are not limited to, atherosclerosis, coronary artery disease, diabetic nephropathy, diabetic neuropathy, diabetic retinopathy, infections of the skin, peripheral vascular disease, stroke, and the like..
The Trustees Of Columbia University In The City Of New York

Radio frequency skin treatment

A device for radio frequency (rf) skin treatment of skin of a user is provided. The device comprises an active electrode and a return electrode.
Koninklijke Philips N.v.

Method for providing rigging tool and providing rigging tool

Disclosed is a method for providing a rigging tool. The method for providing a rigging tool includes receiving an input character, generating a basic rigging at the input character by using a skeleton extraction technique and a skinning weight technique, and providing a skeleton correction function and a skinning weight correction function on the basis of the generated basic rigging..

Methods for treating cancers using ace inhibitors, arb, or celecoxib and olmesartan

Methods for treating cancers, such as breast cancer or skin cancer, using an ace or arb, or a combination of celecoxib and olmesartan.. .

New indication of azelnidipine pharmaceutical composition for treating cancer

A method for treating a cancer includes administering to a subject in need thereof a pharmaceutical composition containing a therapeutically effective amount of azelnidipine or a pharmaceutical acceptable salt thereof. The cancer is selected from the group consisting of a pleural-related cancer, an abdominal-related cancer, an endocrine-related cancer, a gastrointestinal tract-related cancer, osteosarcoma, and skin cancer..

Control method, apparatus and system

The present application provides a control method, apparatus and system. A method comprises: detecting a signal in a circuit; in response to detection of a loopback signal in the circuit, determining that a loop is formed by at least one part of a capacitive touch screen, a device and a user; and in response to formation of the loop, disabling or enabling a function corresponding to the at least one part of the capacitive touch screen.
Beijing Zhigu Rui Tuo Tech Co., Ltd

High throughput sequencing

The invention relates to a high throughput method for determining telomere length of mammalian chromosomal dna; primers for use in said method; a kit comprising said primers; use of said method to diagnose or prognose or to determine the risk of developing a telomere shortening disease such as cancer, ageing, neurological disorders including alzheimer's disease, parkinson's disease and other dementias, brain infarction, heart disease, chronic hiv infection, chronic hepatitis, skin diseases, chronic inflammatory bowel disease including ulcerative colitis, anaemia, atherosclerosis, barrett's oesophagus and cancers including pre-cancerous conditions, infertility, telomere syndromes including dyskeratosis congenita, aplastic anaemia, idiopathic pulmonary fibrosis, familial myelodysplastic syndrome-acute myeloid leukaemia, hoyeraal-hreiderasson syndrome, revesz syndrome, coats plus syndrome, bone marrow failure, and cryptogenic liver cirrhosis. Additionally, the invention also has application in assessing an individual's suitability to be a transplantation donor, for example a bone marrow donor..

Heteroaryl compounds comprising nitrogen and use thereof

The compounds according to the present invention exhibit a remarkable effect on inhibiting proliferation of cancer cells and metastasis and recurrence of cancer with a reduced dose compared to that of existing drugs. Accordingly, the compounds can be effectively used for treating various types of cancer, such as uterine cancer, breast cancer, gastric cancer, brain cancer, rectal cancer, colorectal cancer, lung cancer, skin cancer, blood cancer, pancreatic cancer, renal cancer, prostate cancer, bladder cancer, and liver cancer, and for inhibiting proliferation of cancer cells and metastasis of cancer..

Applicator

Disclosed is an applicator or handpiece configured to apply treatment energy to a segment of skin located in a tissue or skin treatment plane. The treatment energy could be rf energy, applied by a pair of bipolar rf electrodes or optical energy.
Candela Corporation

Skin treatment apparatus and method

Disclosed is a system and a method for aesthetic skin treatment. The system includes an array of rf electrodes assembled on a flexible or rigid substrate.
Syneron Medical Ltd.

Methods and devices for applying closed incision negative pressure wound therapy

A surgical tissue therapy device includes a sealant layer and a collection chamber. The sealant layer functions so as to create a sealed enclosure, or space between it and the surface of a patient, by forming an airtight seal around a surgical area of skin trauma.
Kci Licensing, Inc.

Compositions and methods for treatment of skin disorders

Described herein are compositions and methods of treatment for acne and other skin disorders involving the use of probiotics. In certain aspects, microbes included in the probiotics have been engineered or selected for the treatment of specific skin disorders..
Naked Biome, Inc.

Therapeutic material for skin ulcer

It is an object to provide a therapeutic material for a skin ulcer which has excellent therapeutic effects on intractable skin ulcers such as decubitus ulcers with pockets and huge decubitus ulcers. By applying the therapeutic material for decubitus ulcers consisting of a fibrous material holding an antibiotic and a cell proliferation accelerator therein which is formed into an approximately spherical shape to a site of decubitus in a state in which a defect extending to the dermis, subcutaneous tissue, muscle or bone occurs, it is possible to treat critical skin ulcers such as intractable decubitus ulcers with pockets and huge intractable decubitus ulcers, as well as to treat not only relatively mild decubitus classified as stage ii according to the us national pressure ulcer advisory panel (npuap) staging system, i.e., decubitus having ulcers in a state in which a part of the dermis is deficient, but also severe decubitus that has progressed to stage iii to iv according to the npuap staging system, particularly decubitus with intractable ulcers with pockets or decubitus with huge intractable ulcers..
Omoidesouzou Co., Ltd.

New indication of paroxetine pharmaceutical composition for treating cancer

A method for treating a cancer includes administering to a subject in need thereof a pharmaceutical composition containing a therapeutically effective amount of paroxetine or a pharmaceutical acceptable salt thereof. The cancer is selected from the group consisting of pleural-related cancer, abdominal-related cancer, endocrine-related cancer, gastrointestinal tract-related cancer, osteosarcoma, skin cancer, and blood cancer.
Launx Biomedical Co., Ltd.

New indication of cinacalcet hcl pharmaceutical composition for treating cancer

A method for treating a cancer includes administering to a subject in need thereof a pharmaceutical composition containing a therapeutically effective amount of cinacalcet hcl or a pharmaceutical acceptable salt thereof. The cancer is selected from the group consisting of a pleural-related cancer, an abdominal-related cancer, an endocrine-related cancer, a gastrointestinal tract-related cancer, osteosarcoma, skin cancer, and blood cancer..
Launx Biomedical Co., Ltd.

New indication of monobenzone pharmaceutical composition for treating cancer

A method for treating a cancer includes administering to a subject in need thereof a therapeutically effective amount of a pharmaceutical composition comprising monobenzone or a pharmaceutical acceptable salt thereof. The cancer is selected from pleural-related cancer, abdominal-related cancer, endocrine-related cancer, gastrointestinal tract-related cancer, osteosarcoma, and skin cancer.
Launx Biomedical Co., Ltd.

Determining tissue oxygen saturation with melanin correction

An oximeter probe that takes into account tissue color (e.g., skin color or melanin content) to improve accuracy when determining oxygen saturation of tissue. Light is transmitted from a light source into tissue having melanin (e.g., eumelanin or pheomelanin).
Vioptix, Inc.

Dry skin conductance electrode

The present invention relates to a dry skin conductance electrode for contacting the skin of a user. In order to provide a dry skin conductance electrode for long-term measurements which does not cause problems to the user while still providing a good signal level, the electrode comprises a material made of a noble metal doped with at least one dopant selected from the group consisting of hydrogen, lithium, sodium, potassium, rubidium, caesium and beryllium.
Koninklijke Philips N.v.

N-pyridinyl acetamide derivatives as wnt signalling pathway inhibitors

Disclosed are compounds useful as inhibitors of the wnt signalling pathway. Specifically, inhibitors of porcupine (porcn) are contemplated by the invention.

Fused bicyclic (hetero)aromatic compounds useful for the treatment of cancers

This invention relates to novel compounds. The compounds of the invention are kinase inhibitors.

Apparatus for atmospheric pressure pin-to-hole spark discharge and uses thereof

Disclosed herein are atmospheric pressure pin-to-hole pulsed spark discharge devices and methods for creating plasma. The devices include a conduit for fluidically communicating a gas, a plasma, or both, therethrough, portion of the conduit capable of being connected to a gas supply, and a second portion of the conduit capable of emitting a plasma; a positive electrode comprising a sharp tip; and a ground plate electrode.

Method and machine error detection by combining multiple sensor inputs

A system associated with a medical treatment device for detecting a condition of a patient includes an input device including at least a camera or a microphone. The system also includes a medical treatment device with a controller/classifier and at least one of flow controller, a pump, and/or an alarm output.

Use of regenerative cells in mitigating burn progression and improving skin graft incorporation and healing

Described herein are compositions and methods for the mitigation of burn progression. In particular, the described herein are compositions including regenerative cells for use in preventing and reducing burn progression.

Methods and compositions for treating psoriasis

Method and composition for treating psoriasis and other skin disorders.. .

Compositions for improving the appearance of aging skin

A cosmetic skin care composition for improving the appearance of aging skin. The composition is topically applied to a target area of skin where treatment is desired.

Cosmetic and/or pharmaceutical composition in the form of a dispersion, preparing same and use thereof for skin treatment

A cosmetic, dermatological and/or pharmaceutical composition, in particular for topical use, in the form of a dispersion of a discontinuous internal phase in a continuous external phase. One of the phases is an aqueous phase and the other is an oily phase.

Large area body shaping applicator

A method and apparatus that affect vacuum to massage a volume of the skin and one or more types of skin treatment energies coupled to the massaged volume to treat the skin and subcutaneous adipose tissue and produce a desired treatment effect. The method and apparatus are based on coupling an array or a number of arrays being an assembly of skin treatment units with each skin treatment unit including a hollow cavity and a number of different energy to skin applying elements operative to receive skin treatment energy from a source of such energy and couple or apply the received energy to a treated segment of skin..
Syneron Medical Ltd.

Predicting allergic reactions

This present invention provides a method of predicting immunogenicity and hypersensitivity or allergic reactions to chemical compounds, therapeutics, cosmetics and other chemical compositions. The method uses an in vitro assay employing autologous blood derived cells and an autologous cultured skin biopsy and is of particular utility in the identification and prediction of skin sensitizers that cause allergic contact dermatitis..
Alcyomics Ltd

Antibodies, pharmaceutical compositions and methods

Pharmaceutical composition comprising antibodies or antigen binding fragments thereof that bind to stage-specific embryonic antigen 4 (ssea-4) are disclosed herein, as well as methods of use thereof. Methods of use include, without limitation, cancer therapies and diagnostics.
Obi Pharma, Inc.

Auto-injector systems and delivering cyst medication on demand

An auto-injector device including a syringe, a needle arranged in the vicinity of a first end of the syringe, and a plunger arranged within the syringe. A volume within the syringe between the plunger the needle accommodates medicine, such that movement of the plunger toward the needle dispenses medicine through the needle.

Compositions and methods for the treatment of photoaging and other conditions

Compositions and methods for the treatment of skin disorders or disease are provided.. .
Pro Transit Nanotherapy Llc

Therapeutic or prophylactic agent for itching skin diseases

An antimicrobial peptide ll-37 has an action to promote expression of a nerve repulsion factor sema3a. Ll-37 is a peptide composed of the c-terminal 37 residues of human cathelicidin hcap18.
Toray Industries, Inc.

Topical retinoid compositions

The present application relates to topical compositions. In particular, the present application relates to a topical composition comprising retinoid as active agent, and pharmaceutically acceptable excipient(s), and a process of preparing such compositions.
Dr. Reddy's Laboratories, Ltd.

Device and treating a skin lesion

An electronic device for treating a skin lesion by destroying an affected skin cell using an electric current includes a hollow cylindrical housing with a female casing configured to mate with a male casing via a threading. Further, a printed circuit board is housed within the hollow cylindrical housing and is configured to generate electric current by using a battery.

System and continuing playback in widget after app is backgrounded

This disclosure generally relates to systems and methods that facilitate transitioning a current playback of a video in a video application to a video widget when the video application is moved to a background of a multitasking operating system in which the video application is executing. The transition occurs seamlessly at a point of the current playback in the video application when the video application is moved to the background.
Google Inc.

Method and electronic device for positioning the center of palm

The present invention provides a method and electronic device for palm center positioning, wherein the method for palm center positioning includes the following steps: firstly, acquires an image including a palm and an arm; then acquiring a connection area of the palm and the arm in the image based on skin color feature in the image; subsequently acquiring an exterior contour of the connection area, and clearly defining boundary of the connection area to eliminate errors; and finally acquiring palm center position information according to a maximum value of the shortest distance from each pixel point in the connection area within the exterior contour to the exterior contour. This disclosure is characterized by simple steps and high positioning accuracy..
Le Shi Zhi Xin Electronic Technology (tianjin) Limited

Methods and materials for identifying metastatic malignant skin lesions and treating skin cancer

This document provides methods and materials for identifying metastatic malignant skin lesions (e.g., malignant pigmented skin lesions). For example, methods and materials for using quantitative pcr results and correction protocols to reduce the impact of basal keratinocyte contamination on the analysis of test sample results to identify metastatic malignant skin lesions are provided.
Mayo Foundation For Medical Education And Research

Methods of treating skin disorders using anti-il-31ra antibodies

The present invention relates to methods of treating patients suffering from contact dermatitis, drug induced delayed type cutaneous allergic reactions, toxic epidermal necrolysis, cutaneous t cell lymphoma, bullous pemphigoid, alopecia aereata, vitiligo, acne rosacea, prurigo nodularis, scleroderma, herpes simplex virus, or combination by administering an il-31ra antagonist.. .
Zymogenetics, Inc.

Therapeutic agent for motor disorders

Provided are an agent for the treatment and/or prophylaxis of a movement disorder, the agent for the treatment and/or prophylaxis wherein the movement disorder is extrapyramidal syndrome, the agent for the treatment and/or prophylaxis wherein the movement disorder is bradykinesia, gait disturbance, dystonia, dyskinesia or tardive dyskinesia, the agent for the treatment and/or prophylaxis wherein the movement disorder is a side effect of l-dopa and/or dopamine agonist therapy, and the like, each containing a thiazole derivative represented by the formula (i) wherein r1 represents aryl and the like, and r2 represents pyridyl or the like, or a pharmaceutically acceptable salt thereof as an active ingredient.. .
Kyowa Hakko Kirin Co., Ltd.

N-pyridinyl acetamide derivatives as inhibitors of the wnt signaling pathway

Disclosed are compounds useful as inhibitors of the wnt signalling pathway. Specifically, inhibitors of porcupine (porcn) are contemplated by the invention.
Redx Pharma Plc

Allosteric modulators of nicotinic acetylcholine receptors

The present disclosure relates to compounds of formula i that are useful as modulators of α7 nachr, compositions comprising such compounds, and the use of such compounds for preventing, treating, or ameliorating disease, particularly disorders of the central nervous system such as cognitive impairments in alzheimer's disease, parkinson's disease, and schizophrenia, as well as for l-dopa induced-dyskinesia and inflammation. .
Merck Sharp & Dohme Corp.

Uses of mesembryanthemum crystallinum l. callus extract in delaying skin cell aging, nursing skin, treating and preventing skin cancer

Use of mesembryanthemum crystallinum l. Callus extract in the manufacture of a medicament or a skin care product, wherein the medicament or skin care product is for at least one of delaying skin cell aging, nursing skin, repairing skin, treating skin cancer, and preventing skin cancer..
Tci Co., Ltd.

Wound fluid elevated protease enzyme inhibition through camelid blood products

Camelid blood products their peptide isolates and synthetic sequences for wound fluid elevated protease enzyme inhibition. The present invention provides evidence that metalloprotease and other protease enzyme (e.g.

Skin tag remover

The present invention is a skin tag remover which includes a cord formed into a loop at a tag end for placing around a skin tag, a cord housing for receiving a portion of the cord there through and a finger ring attached to a ring end of the cord. Pulling on the finger ring tightens the loop around the skin tag and places the cord into a constricted position so that blood flow is restricted to the skin tag.

Conjugates of ph low insertion peptide and monomethyl auristatins in the treatment of solid tumors

Constructs comprising ph low insertion peptide and variants thereof conjugated to monomethyl auristatins and analogs thereof are described. These constructs are useful, for example, in the treatment of solid tumors, including the treatment of breast cancer and prostate cancer, as well as other cancers such as pancreatic cancer, ovarian cancer, cervical cancer, uterine cancer, lung cancer, skin cancer, kidney cancer, and colon cancer.
Lehigh University

Benzoxazinone derivatives for treatment of skin diseases

The present invention relates to methods and compositions for inhibiting the activity of skin proteases, especially human kallikrein 7 (klk7), human kallikrein 5 (klk5), and human kallikrein 14 (klk14). More specifically, the invention relates to the use of substituted 3,1-benzoxazin-4-ones being selective inhibitors of human skin kallikreins for the treatment of skin diseases, more specifically for the treatment of inflammatory skins diseases, especially netherton syndrome..
Sixera Pharma Ab

Skin treatment method and apparatus

The application discloses a number of methods and apparatuses suitable for selective skin treatment have been described. In one example, a pair of rf electrodes is applied to skin.
Candela Corporation

Apparatus for forming delivery path for composition for treatment and auxiliary assembly for skin treatment including same

The present invention relates to an apparatus for forming a delivery path for a composition for treatment and an auxiliary assembly for skin treatment including the same, and provides an apparatus for forming a delivery path for a composition for treatment and an auxiliary assembly for skin treatment including the same, the apparatus comprising: a light source; a light irradiating unit for receiving a light from the light source to irradiate the light on a surface of skin; and a control unit for controlling a pulse waveform of a light irradiated through the light irradiating unit so as to form a plurality of pores, which form a path through which a composition applied on the surface of the skin is transferred inside, on the surface of the skin after irradiating the light.. .
Lutronic Corporation

Devices and methods for skin treatment

According to some embodiments, a system for treating skin includes a handpiece assembly comprising a tip and a main body portion, the main body portion comprising an interior cavity and at least one canister configured to store at least one of a treatment material and a waste material. The treatment material and/or the waste material is in fluid communication with the tip..
Edge Systems Llc

Topical formulation for skin care

Disclosed herein is a method of preparing a subject's cells for topical treatment of a subject in need. Also provided is a topical formulation and methods of treating a subject suffering a skin disorder and pain using the topical formulation.
Aesthetics Biomedical, Inc.

Acetic acid and hypochlorous acid compositions for treatment of biofilms and wound care

Disinfecting compositions containing hypochlorous acid and acetic acid are useful for treating biofilms in or on tissue, including biofilms related to wounds or other skin trauma. The compositions are useful for treating a variety of types of tissue, both on the surface on beneath the surface of tissue.
Softox Solutions As

Pharmaceutical compositions for combination therapy

This invention relates to novel pharmaceutical compositions comprising a therapeutically effective combination of a dopaminergic stabilizer known as pridopidine, and an inhibitor of the vesicular monoamine transporter type 2 (vmat) known as tetrabenazine. The pharmaceutical compositions for use according to the invention are contemplated particularly useful for improving the symptomatic therapeutic effects, and for reducing the adverse effects, of tetrabenazine in the treatment of movement disorders, and in particular movement disorders associated with huntington's disease, gilles de la tourette's syndrome, or tardive dyskinesia..
Teva Pharmaceuticals International Gmbh

Pluripotent stem cell for treating diabetic skin ulcer

The purpose of the present invention is to provide a novel medicinal use in regeneration medicine, said medicinal use comprising using pluripotent stem cells (muse cells). Provided is a cell preparation for treating skin ulcer, said cell preparation comprising ssea-3 positive pluripotent stem cells isolated from a mesenchymal tissue of a living organism or cultured mesenchymal cells.
Tohoku University

Topical formulations comprising a steroid

The application provides formulations for the topical administration of an active agent comprising at least one steroid, in the form of topical sprays that are propellant-free, and/or substantially non-foaming, and/or alcohol-free. The present application also provides processes for preparing such compositions and methods of using them in management of skin diseases or disorders such as psoriasis, dermatoses, and other associated skin diseases or disorders..
Dr. Reddy's Laboratories Ltd.

Topical skin care formulations comprising botanical extracts

Disclosed is a topical skin composition comprising an aqueous extract from a part of nymphaea gigantea, wherein said part consists of the flower of nymphaea gigantea, an aqueous extract from a part of plumeria alba, wherein said part consists of the flower of plumeria alba, and a dermatologically acceptable vehicle.. .
Mary Kay Inc.

Luminate face lotion

The present invention features novel cosmetic skin care compositions for improving the appearance of skin, particularly the reducing the appearance of age spots and discoloration.. .
Jan Marini Skin Research

Modular device and data management system and gateway for a communications network

A gateway provides duplex-directional, multimedia ad hoc mesh networking, peer-to-peer direct communications, power optimization, dynamic configuration, and data management, while operating within various devices and network topologies. A multitasking virtual machine monitor for mobile networked devices, that is capable of functional expandability and portability to various operating environments, interoperability with a variety of operating systems, the gateway control system (gcs) performs functional capabilities in both a local and a networked topology using local and remote hardware and software.
Eyecam, Llc

Coating composition comprising anti-skinning agent

The invention relates to a coating composition comprising an oxidatively drying binder and an anti-skinning agent, the anti-skinning agent comprising: a) a diketone of formula (i) (b) an aldoxime or ketoxime of formula (ii) wherein r1, r2, r3, r4 and n have the same meaning as that defined by the present application.. .
Ppg Europe B.v.

Low intensity magnetic field device for cosmetic skin treatment

Devices and methods for cosmetic skin treatment using a magnetic field are provided. A device can include a case, a stimulation head coupled with the case and including at least one coil of conductive wire for generating a magnetic field, and an electronic circuit housed in the case for driving the coils to generate the magnetic field..
The Florida International University Board Of Trustees

Topical skin compositions for treating wrinkles

Disclosed is a method for reducing the appearance of a wrinkle on skin comprising topically applying to said wrinkle a composition that includes an effective amount of ornithine, retinol, commiphora mukul resin or an extract thereof, and hyaluronic acid, wherein topical application of the composition reduces the appearance of said wrinkle within 120 seconds after application of the composition, and wherein topical application of said composition stimulates adipogenesis in said skin.. .
Mary Kay Inc.

A light-based collagen measurement system and a skin treatment system

A measurement system for light-based measurement of collagen, using a first light intensity and a second light intensity according to the invention, compromises a light source (120) for emitting a light beam having a source wavelength range and an optical system (130) to polarize light within the source wavelength range, thereby generating a polarized light beam (140), and to direct and focus the polarized light beam (140) to a target position inside the skin (160) at a predetermined focus depth below an outer surface of the skin. The measurement system further comprises a first detector (150) and a second detector.
Koninklijke Philips N.v.

Methods and systems for controlling or tuning the electric field generated in skin or tissue during cold plasma skin treatments

Exemplary systems and methods associated with skin treatments using non-thermal plasma to porate skin or tissues using conductive elements to direct an electric field through targeted regions of the skin or tissue. Various configurations of conductive elements and associated circuitry may be used to tune and control the electric field..
Ep Technologies Llc

Compositions and methods for treatment of pre-cancerous skin lesions

The present disclosure encompasses compositions and methods for the treatment of precancerous skin lesions. Compositions of the invention comprise a cytotoxic agent and a thymic stromal lymphopoietin (tslp) inducer..
Washington University

Topical healing and scar treatment composition

Topical aqueous compositions are effective in minimizing scar formation and improving the visual appearance of scars. The compositions are also effective in treating numerous skin disorders, including acne, psoriasis, and eczema..

Compositions of bioactive fulvate fractions and uses thereof

Compositions with fulvate fractions alone or in combination with growth factors, bioactive fragmented peptides, or combinations thereof are disclosed herein. Also disclosed are methods of using said compositions for the catalyzing cellular regeneration, including the healing, treatment, or prevention of skin disorders.
Omni Bioceutical Innovations, Inc.

Novel d3 dopamine receptor agonists to treat dyskinesia in parkinson's disease

The present invention provides a method of inhibiting, suppressing or preventing levodopa-induced dyskinesia in a patient suffering from parkinson's disease, comprising the step of administering to the patient a pharmaceutical composition comprising at least one compound of the invention. The present invention further provides a method of inhibiting, suppressing or preventing parkinson's disease in a patient, comprising the step of administering to the patient a pharmaceutical composition comprising at least one compound of the invention..
Rutgers, The State University Of New Jersey

Appliance for treatment of facial skin conditions

A mask member which fits over a portion of the face of a user. A retaining member holds the mask in place on the user's head.
L'oreal

Squeezable nail treatment container

An apparatus is provided for providing nail or skin treatment. The apparatus includes a container, formed of a compressible material; an insert, disposed within the container formed of a compressible material, and configured to receive and surround at least one body part of the user; and an opening at a first end of the container which provides access to an interior surface of the insert, wherein the insert is configured to hold at least one substance configured to treat at least one of a nail and skin of the user..
L'oreal

Systems and methods for presenting and interacting with a picture-in-picture representation of video content on an electronic device with a touch-sensitive display

Systems and methods for multitasking using touch-sensitive devices are disclosed herein. In one aspect, a method includes: playing video content in a full-screen mode on a touch-sensitive display of an electronic device.
Apple Inc.

Structure-preserving composite model for skin lesion segmentation

A structure-preserving composite model for skin lesion segmentation includes partitioning a dermoscopic image into superpixels at a first scale. Each superpixel is a vertex on a graph defined by color coordinates and spatial coordinates, and represents a number of pixels of the dermoscopic image according to the first scale.
International Business Machines Corporation

Systems and methods for activating a multi-tasking mode using an application selector that is displayed in response to a swipe gesture on an electronic device with a touch-sensitive display

Systems and methods for multitasking using touch-sensitive displays are disclosed. An example method includes: displaying a first application on a touch-sensitive display (tsd) of an electronic device; detecting, via the tsd, a swipe gesture that moves over part of the first application; in response to detecting the swipe gesture, displaying an application selector with a set of affordances, and the application selector is (i) displayed in a predefined portion of the tsd and (ii) overlays at least a portion of the displayed first application; detecting an input at an affordance of the set of affordances; in response to detecting the input: (i) ceasing to display the application selector; (ii) displaying a second application corresponding to the selected affordance in the predefined portion that was previously used to display the application selector; and (iii) resizing the first application to occupy a remaining portion of the tsd adjacent to the predefined portion..
Apple Inc.

Presence of phosphorylated tau protein in the skin of neurodegenerative disease and scis, scc, and bcc

The presence of misfolded proteins in the brain is the hallmark of neurodegenerative diseases. Protein aggregates could have systemic expression and might be found in several tissues including the skin.

Modulating gamma-c-cytokine activity

Peptide antagonists of γc-family cytokines, which is associated with important human diseases, such as leukemia, autoimmune diseases, collagen diseases, diabetes mellitus, skin diseases, degenerative neuronal diseases and graft-versus-host disease (gvhd). Thus, inhibitors of γc-cytokine activity are valuable therapeutic and cosmetic agents as well as research tools.
Bioniz, Llc

Chemical inhibitors of sebocyte function

The present discovery pertains to the discovery of certain amphiphilic compounds that may be useful for the management of sebum secretion in subjects with acne, oily skin, or seborrheic dermatitis. These compounds are 1-dialkylphosphorylalkanes with the longest alkyl group being seven or more carbons.

Systems and methods for skinning articles

A system for delivering and applying a flowable mixture to an article (311-313) is disclosed. The system includes a mixture delivery system (200) and a skinning system (300).
Corning Incorporated

Compositions and methods comprising extracts of zingiberaceae

The present technology relates to compositions, in particular, cosmetic, topical and pharmaceutical compositions, comprising extracts of plants in the family zingiberaceae, as well as methods in connection with such compositions, including methods of reducing sebum production, reducing the appearance of oily skin, reducing the appearance of acne, reducing the appearance of pores, reducing the appearance of wrinkles, reducing free radicals, reducing baldness, reducing or increasing hair growth and reducing or increasing androgenic stimulation, or reducing the rate of oxidation.. .
Biocogent, Llc

Method for treating skin cancer

A method for treating skin cancer including the steps of applying an isothiocyanate functional surfactant to an area affected by skin cancer, wherein the isothiocyanate functional surfactant comprises at least one isothiocyanate functional group associated with an aliphatic and/or aromatic carbon atom of the isothiocyanate functional surfactant.. .

Toxic aldehyde related diseases and treatment

The present invention provides for the treatment, prevention, and/or reduction of a risk of a disease, disorder, or condition in which aldehyde toxicity is implicated in the pathogenesis, including ocular disorders, skin disorders, conditions associated with injurious effects from blister agents, and autoimmune, inflammatory, neurological and cardiovascular diseases by the use of a primary amine to scavenge toxic aldehydes, such as mda and hne.. .
Aldeyra Therapeutics, Inc.

Immune regulatory oligonucleotide (iro) compounds to modulate toll-like receptor based immune response

The invention provides novel immune regulatory oligonucleotides (iro) as antagonist of tlrs and methods of use thereof. These iros have unique sequences that inhibit or suppress tlr-mediated signaling in response to a tlr ligand or tlr agonist.
Idera Pharmaceuticals, Inc.

Cancer therapeutics

This invention relates to compounds that bind to wild-type cbfβ and inhibit cbfβ binding to runx proteins. The potent compounds of the invention inhibit this protein-protein interaction at low micromolar concentrations, using allosteric mechanism to achieve inhibition, displace wild-type cbfβ from runx1 in cells, change occupancy of runx1 on target genes, and alter gene expression of runx1 target genes.
University Of Virginia Patent Foundation

Apparatus and skinning articles

A skinning apparatus and a method of skinning a porous ceramic. The apparatus includes an axial skinning manifold.
Corning Incorporated

Methods of use for 2,5-dihydroxybenzene sulfonic acid compounds for the treatment of cancer, rosacea and psoriasis

The invention describes compositions and methods of use for 2,5-dihydroxybenzene sulfonic acid compounds and pharmaceutically acceptable salts thereof. The invention provides methods for (a) treating skin cancer; (b) treating cancer of the organs; (c) treating leukemia; (d) improving the efficacy of chemotherapy, radiation therapy and/or cancer immunotherapy; (e) treating rosacea; and (f) treating psoriasis by administration of a composition comprising at least one 2,5-dihydroxybenzene sulfonic acid compound or a pharmaceutically acceptable salt thereof, and, optionally at least one therapeutic agent.
Amderma Pharmaceuticals, Llc

Hybrid mobile interactions for native apps and web apps

There is disclosed a system, including apparatus, methods and computer programs, for running native software applications (apps) and html5 web-based apps on a computing device, particularly a mobile computing device, in a multitasking mode of operation. In one embodiment, touch screen displays having one or more browsers are adapted to run one or more html5 apps, and receive input from hand gestures.
Intel Corporation

General-purpose reconfigurable conduit and reaction chamber microfluidic arrangements for lab-on-chip and miniature chemical processing

A general-purpose software-reconfigurable chemical process system useful in a wide range of applications is disclosed. Embodiments may include software control of internal processes, automated provisions for cleaning internal elements with solvents, provisions for clearing and drying gasses, and multitasking operation.

Methods, compositions and apparatuses for treating psoriasis by phototherapy

Compositions, methods and apparatuses for phototherapy to treat skin disorders. In particular, described herein are methods, compositions, phototherapy dressings for use with phototherapy uv light applicators (sources) and phototherapy uv light applicators to treat skin disorders such as psoriasis..

Devices and methods for treating the skin using a porous member

According to some embodiments, a skin treatment assembly comprises a tip comprising a proximal end and a distal end, a container configured to secure to the tip along the proximal end of the tip, wherein the container is configured to contain a liquid, and a porous member configured to extend at least partially within an interior of the container such that it contact a liquid contained within the container, wherein the porous member is configured to extend at least partially within an interior of the tip and is configured to facilitate the transfer of liquid from the container to the distal end of the tip.. .
Edge Systems Llc

Hydrogels for treating and ameliorating wounds and methods for making and using them

In alternative embodiments, provided are compositions, e.g., pharmaceutical compositions, formulations, kits and other products of manufacture, comprising a hydrogel and active ingredients, including mixed thickness skin micrografts, or full or split-thickness skin grafts, contained or mixed in or within the hydrogel; and methods for making and using them. In alternative embodiments, compositions and methods as provided herein are used for the treatment or amelioration of wounds and surgical sites, and include compositions and methods for micrografting, or for micrografting a wound, or for micrografting a wound for rapid re-epithelialization, or for micrografting a wound for rapid re-epithelialization of large non-healing wounds..
Vicus Therapeutics, Llc

Phospholipid-containing marine extracts for treatment of cardiovascular diseases

The present invention relates to a method of treatment and/or prevention of cardiovascular disease, rheumatoid arthritis, skin cancer, premenstrual syndrome, diabetes and transdermal transport enhancement. The method comprises the administration of a therapeutically effective amount of krill and/or marine oil to a patient.
Neptune Technologies & Bioressources, Inc.

Method for avoiding or inhibition of dyskinesia

Certain neurological disorders are treated with dopamine agonists (e.g. L-dopa) but these treatments unintentionally cause levodopa-induced dyskinesias (lids) or tardive dyskinesia.
Research Foundation Of The City University Of New York

Compositions for nail and skin treatment

Novel topical compositions for the treatment of nail and skin afflictions comprising at least one active agent, at least one volatile solvent, at least one film-forming ingredient and at least one phospholipid, processes for their preparation and methods of treatment of nail and skin afflictions. Following application of the compositions and evaporation of volatile solvents, the composition produces a film, which has web-like structures containing the active agent(s)..
Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd

Protective skin compositions

The subject of the present invention is cosmetic or pharmaceutical compositions which are protective against common skin irritants or allergens. The invention is also directed to the use of these compositions to protect skin from the effects of metal.
Amantin Experts

Methods for preparing a skin graft

The present invention generally relates to methods for applying a skin graft. Methods of the invention involve harvesting an epidermal skin graft, and applying the epidermal skin graft to a recipient site such that the basal layer of the skin graft makes direct contact with the recipient site..
Kci Licensing, Inc.

Optical transfer diagnosis for detection and monitoring of tissue disorders

Systems and methods for discriminating between malignant and benign pigmented skin lesions based on optical analysis using spatial distribution maps, morphological parameters, and additional diagnostic parameters derived from images of tissue lesions. A handheld optical transfer diagnosis device is disclosed capable of capturing a series of reflectance images of a skin lesion at a variety of angles of illumination and observation..
Balter, Inc.

Method and electronic displaying reference locations for locating ecg pads and recording medium using the method

A method and an electronic apparatus for displaying reference locations for locating ecg pads and a recording medium using the method are provided. In the method, a body image is retrieved and a skin area in accordance with a skin color in the body image is detected.
Htc Corporation

N-(4-hydroxy-4-methyl-cyclohexyl)-4-phenyl-benzenesulfonamides and n-(4- hydroxy-4-methyl-cyclohexyl)-4-(2-pyridyl)benzenesulfonamides and their therapeutic use

The present invention pertains generally to the field of therapeutic compounds. More specifically the present invention pertains to certain substituted n-(4-hydroxy-4-methyl-cyclohexyl)-4-phenyl-benzenesulfonamide and n-(4-hydroxy-4-methyl-cyclohexyl)-4-(2-pyridyl)benzenesulfonamide compounds (collectively referred to herein as hmc compounds) that are useful, for example, in the treatment of disorders (e.g., diseases) including, inflammation and/or joint destruction and/or bone loss; disorders mediated by excessive and/or inappropriate and/or prolonged activation of the immune system; inflammatory and autoimmune disorders, for example, rheumatoid arthritis; psoriasis; psoriatic arthritis; chronic obstructive pulmonary disease (copd); asthma; atherosclerosis; inflammatory bowel disease; ankylosing spondylitis; multiple sclerosis; systemic lupus erythematosus; sjogren's syndrome; a disorder associated with bone loss, such as bone loss associated with excessive osteoclast activity in rheumatoid arthritis, osteoporosis, cancer-associated bone disease, or paget's disease; cancer, such as a haematological malignancy, such as multiple myeloma, leukemia, or lymphoma, or a solid tumour cancer, such as bladder cancer, breast cancer (female and/or male), colon cancer, renal cell carcinoma, kidney cancer, lung cancer, pancreatic cancer, gastric cancer, prostate cancer, brain cancer, skin cancer, thyroid cancer, basal cell ameloblastoma, or melanoma; a disorder associated with fibrosis, such as systemic sclerosis or scleroderma; or a rare vasculitide, such as behçet's disease.
Pimco 2664 Limited

Skin treatment device

The present invention is concerned with a skin treatment device, in particular a temporal hair removal device, having a light emission unit having a substrate, a plurality of first led dies mounted on the substrate on an area of at least 0.2 cm2, in particular of at least 1.0 cm2, where the first led dies are each arranged for emitting light at a first peak emission wavelength in the far red or infrared wavelength range of between 700 nm and 980 nm, and at least one second led die arranged for emitting light at a second peak emission wavelength in the visible wavelength range of between 400 nm and below 700 nm, wherein the skin treatment device is arranged to activate the first led dies to emit a treatment light pulse, the treatment light pulse in particular having a pulse length of between 10 ms and 300 ms, and the first led dies have a radiant flux such that a radiant fluence on the skin of a user of at least 1 j/cm2 is achieved by application of the treatment light pulse, and the skin treatment device is arranged to activate the at least one second led die to emit a visible light pulse simultaneously with the emission of the treatment light pulse.. .
Braun Gmbh

Fenestrated bone wrap graft

The present invention relates to a fenestrated bone wrap graft and a method of preparing cortical bone in thin sheets then fully demineralizing it to give it formed flexibility and then creating fenestrations in the cortical bone in a fashion similar to, but not identical to, skin grafts.. .
Vivex Biomedical, Inc.

Aldose reductase inhibitors and uses thereof

The present invention relates to novel compounds and pharmaceutical compositions thereof, and methods for promoting healthy aging of skin, the treatment of skin disorders, the treatment of cardiovascular disorders, the treatment of renal disorders, the treatment of angiogenesis disorders, such as cancer, treatment of tissue damage, such as non-cardiac tissue damage, the treatment of evolving myocardial infarction, and the treatment of various other disorders, such as complications arising from diabetes with the compounds and compositions of the invention. Other disorders can include, but are not limited to, atherosclerosis, coronary artery disease, diabetic nephropathy, diabetic neuropathy, diabetic retinopathy, infections of the skin, peripheral vascular disease, stroke, and the like..
The Trustees Of Columbia University In The City Of New York

Aldose reductase inhibitors and uses thereof

The present invention relates to novel compounds and pharmaceutical compositions thereof, and methods for promoting healthy aging of skin, the treatment of skin disorders, the treatment of cardiovascular disorders, the treatment of renal disorders, the treatment of angiogenesis disorders, such as cancer, treatment of tissue damage, such as non-cardiac tissue damage, the treatment of evolving myocardial infarction, and the treatment of various other disorders, such as complications arising from diabetes with the compounds and compositions of the invention. Other disorders can include, but are not limited to, atherosclerosis, coronary artery disease, diabetic nephropathy, diabetic neuropathy, diabetic retinopathy, infections of the skin, peripheral vascular disease, stroke, and the like..
The Trustees Of Columbia University In The City Of New York

Compounds, formulations, and methods for treating or preventing inflammatory skin disorders

Wherein each of b1, b2, and b3 is independently hydrogen, hydroxy, or alkoxy; and each of b4 and b5 is independently hydrogen or alkyl, applying such compounds topically as sprays, mists, aerosols, solutions, lotions, gels, creams, ointments, pastes, unguents, emulsions, and suspensions to treat inflammatory skin disorders and the symptoms associated therewith.. .

Skin compositions and uses

The present invention provides a skin care composition for maintaining or improving the healthy appearance of the skin of an individual and/or rejuvenate the skin of an individual. A skin care composition comprises active ingredients, including, without limitation, growth factors, anti-oxidants, curcuminoids, oils and/or red rice extracts.
Stemetrix, Inc.

Skin treatment device

The present invention is concerned with a skin treatment device, in particular a hair removal device, having a light emission unit comprising a substrate and a plurality of first led dies mounted on the substrate on an area of at least 0.2 cm2, in particular of at least 1 cm2, wherein the skin treatment device is arranged to activate the first led dies to emit a treatment light pulse having a pulse length in particular in the range of between 10 ms and 300 ms and the first led dies have a radiant flux such that a radiant fluence on the skin of a user of at least 1 j/cm2 is achieved by application of the treatment light pulse, wherein the light emission unit has at least two selectable active areas of first led dies, where the selectable active areas have different sizes, and at least three second led dies are mounted on the substrate at locations suitable for visibly indicating each of the selectable active areas.. .
Braun Gmbh

Propolis and extracts thereof for the treatment of skin cancers and improvement of skin health

This invention provides pharmaceutical and cosmeceutical compositions, including anti-skin cancer compositions, n containing propolis and cyclodextrin, and compositions comprising one or more compounds present in propolis, including compositions comprising one or more compounds present as an inclusion complex with cyclodextrin. Methods of using such compounds and compositions, in particular in the treatment or prevention of skin cancers and skin disorders, and in enhancing skin health, are also provided..
Manuka Health New Zealand Limited

Nitric oxide topical application apparatus and methods

A topical application of nitric oxide may be provided by two separate containers, each containing an active component media to produce nitric oxide when combined. For example, a nitrite component media may be contained in one dispenser and an acidified component media may be contained in another dispenser.
Syk Technologies, Llc

Silicone-based biophotonic compositions and uses thereof

The present disclosure provides silicone-based biophotonic compositions and methods useful in phototherapy. In particular, the silicone-based biophotonic compositions of the present disclosure include a silicone phase and a surfactant phase, wherein the surfactant phase comprises at least one chromophore solubilized in a surfactant.
Klox Technologies Inc.

Methods of chemical synthesis and purification of diaminophenothiazinium compounds including methylthioninium chloride (mtc)

This disclosure pertains generally to the field of chemical synthesis and purification, and more specifically to methods of synthesizing and purifying certain 3,7 diamino-phenothiazin-5-ium compounds (referred to herein as “diaminophenothiaziniumcompounds”) including methythioninium chloride (mtc) (also known as methylene blue). In one embodiment, the method comprises the steps of, in order: nitrosylation (nos); nitrosyl reduction (nr); thiosulfonic acid formation (tsaf); oxidative coupling (oc); cr(vi) reduction (cr); isolation and purification of zwitterionic intermediate (iapozi); ring closure (rc); chloride salt-formation (csf); one of: sulphide treatment (st); dimethyldithiocarbamate treatment (dt); carbonate treatment (ct); ethylenediaminetetraacetic acid treatment (edtat); organic extraction (oe); and recrystallisation (rx).
Wista Laboratories Ltd.

Selective serotonin 2a/2c receptor inverse agonists as therapeutics for neurodegenerative diseases

Behavioral pharmacological data with the compound of formula (i), a novel and selective 5ht2a/2c receptor inverse agonist, demonstrate in vivo efficacy in models of psychosis and dyskinesias. This includes activity in reversing mk-801 induced locomotor behaviors, suggesting that this compound may be an efficacious anti-psychotic, and activity in an mptp primate model of dyskinesias, suggesting efficacy as an anti-dyskinesia agent.
Acadia Pharmaceuticals Inc.

Biophotonic compositions comprising halogen and uses thereof

The present disclosure provides biophotonic compositions containing halogen ions and/or halogen salts and methods useful in phototherapy. In particular, the biophotonic compositions comprising halogen of the present disclosure include at least one chromophore; and halogens and/or halogen salts such ki, or kcl, or kbr, or csbr, or mgbr2, or znbr2, or naf, or nacl, or nabr, or i2, or i3−, or br2, or cl2.
Klox Technologies Inc.

Abrasive skin treatment device

An abrasive skin treatment device including a handle portion, a head portion including an exfoliating element, and a unitary pivoting mechanism providing relative movement between the handle portion and the head portion along at least two planes.. .
Telebrands Corp.

Abrasive skin treatment device

An abrasive skin treatment device including a handle portion, a head portion including an exfoliating element, and a unitary pivoting mechanism providing relative movement between the handle portion and the head portion along at least two planes.. .
Telebrands Corp.

Method and an providing a multitasking view

According to an aspect, there is provided a method and an apparatus for providing a multitasking view. Task information of a task executed on a first device and a preview image of the executed task is received.
Microsoft Technology Licensing, Llc

Method of designing a peptide and/or peptide derivative for modulating gamma-c-cytokine activity

The γc-family cytokines, interleukin-2 (il-2), interleukin-4 (il-4), interleukin-7 (il-7), interleukin-9 (il-9), interleukin-15 (il-15), and interleukin-21 (il-21), are associated with important human diseases, such as leukemia, autoimmune diseases, collagen diseases, diabetes mellitus, skin diseases, degenerative neuronal diseases and graft-versus-host disease (gvhd). Thus, inhibitors of γc-cytokine activity are valuable therapeutic and cosmetic agents as well as research tools.
Bioniz, Llc

Pharmaceutical composition for preventing or treating skin rash

Provided is a method for preventing or treating skin rash comprising administering to a subject in need thereof epidermal growth factor as an active ingredient. The skin rash includes a skin disorder caused by administering an epidermal growth factor receptor inhibitor, such as erlotinib, as an adverse event..
Dong-a University Research Foundation For Industry-academy Cooperation

Method for producing mycosporine-like amino acid using microbes

Provided are: a method for producing a mycrosporine-like amino acid (maa) that includes a step in which microbes are cultivated that produce maa on the outside of bacterial cells, a step in which the bacterial cells and extracellular culture fluid are separated, and a step in which the maa is recovered from the extracellular culture fluid; an maa indicated by formula (1), an maa produced using this method, or an ultraviolet-absorbing composition including the maa indicated by formula (1); and a composition including the maa produced using this method or the maa indicated by formula (1), for preventing at least one symptom or disease selected from a group comprising acute skin reactions, aging of the skin, and skin cancer.. .
Nagase & Co., Ltd.

Sensor inserter having introducer

Methods, device and system for providing a sensor insertion assembly including an inserter housing, an introducer including a body portion having a proximal end and a distal end and a shaft portion comprising a channel and a distal end, the shaft portion extending downwardly from an edge of the body portion, the shaft portion including a holding member disposed along a length of the channel, the holding member configured to substantially releasably retain a sensor, an on-body electronics unit, wherein the introducer is configured for insertion of the sensor through an aperture in the on-body electronics unit prior to insertion through skin and a drive mechanism included in the inserter housing and operatively coupled to the introducer, wherein the drive mechanism drives the introducer and retained sensor through the skin are provided.. .
Abbott Diabetes Care Inc.

Device, system, method and kit for preparing skin

A skin treatment device having a substrate having a first surface and a second surface, and an adhesive layer covering at least a portion of the first surface of the substrate. When the adhesive layer is applied to the skin surface of a mammal and removed, hair is removed at the follicle.
Full Power Aed, Llc

Nurr1 as a genetic target for treating levodopa-induced dyskinesias in parkinson's disease

Methods of treating movement disorders by reducing the activity of nurr1 are disclosed. These methods are particularly applicable to subjects suffering from parkinson's disease who have either developed levodopa-induced dyskinesia (lid) or are at risk of developing lid.
Board Of Trustees Of Michigan State University

Enantiomers of 8-hydroxyquinoline derivatives and the synthesis thereof

The subject matter of the invention furthermore relates to a novel, stereoselective synthesis for the preparation of the novel enantiomer derivatives according to the invention. The novel medicinal and/or pharmaceutical compositions comprising these enantiomers are suitable for the treatment of the named diseases, and the enanatiomers are used for manufacture of these compositions.

Skin lightening compounds

The present invention provides a compound of formula i, ii or iii or a salt or prodrug derivative thereof that is a skin-lightening agent useful for the inhibition of melanin synthesis and/or the removal of existing melanin to function as a skin-lightening agent.. .
Wisys Technology Foundation Inc.

Composition comprising gpcr19 agonist as an active ingredient for preventing or treating allergic dermatitis

The present invention is about a pharmaceutical composition, an oral preparation, and an injection preparation containing a g protein-coupled receptor19 (gpcr19) agonist, specifically sodium taurodeoxycholate(hy2191) and its derivative, as an active ingredient for preventing or treating allergic skin diseases. The present invention is also about an external preparation and a cosmetic composition containing said pharmaceutical composition for preventing and improving allergic skin diseases.
Shaperon Inc.

Method for evaluating condition of skin dryness

To provide a method for quickly and accurately evaluating a condition of skin dryness and a method for efficiently searching a substance to improve dry skin. A method for evaluating a condition of skin dryness, the method comprising measuring the expression levels of agr2 and/or agr3 in skin cells collected from subjects..
Kao Corporation

Methods of preparing materials with ammonia oxidizing bacteria and testing materials for ammonia oxidizing bacteria

This disclosure provides, inter alia, systems and methods for testing products for ammonia oxidizing bacteria, quality control, and providing products with ammonia oxidizing bacteria. The systems and methods herein may be used, inter alia, to treat diseases associated with low nitrite levels, skin diseases, and diseases caused by pathogenic bacteria..
Aobiome Llc

Urea and amide derivatives of aminoalkylpiperazines and use thereof

The compounds can be used for treating a patient suffering from a condition that is capable of treatment with a partial agonist or antagonist of the dopamine d2/d3 receptors. The compounds are especially useful for patients suffering from schizophrenia, depressions, neurodegenerative diseases such as parkinson's, dyskinesias, substance abuse and relapse to substance abuse and addiction to substances such as cocaine, methamphetamine, nicotine and alcohol, glaucoma, cognitive disorders, restless leg syndrome, attention deficit hyperactivity disorders, hyperprolactinemia, autism, motor disturbances such as akathisia, rigor, dystonias as well as various disorders of the urinary tract and other neurologic disorders.

Radio frequency skin treatment device

The invention relates to a device (1) for skin treatment comprising a non-circular symmetrical outer electrode and at least two inner electrodes (20; 22) surrounded by the outer electrodes. An rf generator (16) is arranged to supply an rf voltage between the inner electrodes and the outer electrode.
Koninklijke Philips N.v

Centrosymmetric radio frequency electrode configuration for skin treatment

The invention relates to a device (100) for rf skin treatment comprising an outer electrode (2) arranged on an operational side (15) of the device. The outer electrode has an annular or equilateral polygonal shape.
Koninklijke Philips N.v.

Hatching fluid enzymes and uses thereof

The present invention relates to various polypeptides from fish hatching fluid, their encoding nucleic acid sequences, pharmaceutical compositions comprising said polypeptides and nucleic acid molecules and their use in various medical and cosmetic applications to the skin, particularly for moisturizing skin and/or for exfoliation of the horny layer of the skin for treating or preventing skin disorders or conditions in an animal.. .
Aqua Bio Technology Asa

Systems and methods for storage and delivery of ammonia oxidizing bacteria

This disclosure provides, inter alia, systems and methods for storage and delivery of ammonia oxidizing bacteria, and preparations comprising ammonia oxidizing bacteria. The ammonia oxidizing bacteria may be provided in a container or a kit, with one or more other components that may enhance delivery.
Aobiome Llc

Methods and compositions for sleep disorders and other disorders

Use of particular substituted heterocycle fused gamma-carboline compounds as pharmaceuticals and pharmaceutical compositions comprising them for the treatment of one or more disorders involving the 5-ht2a, sert and/or dopamine d2 pathways are disclosed. In addition, the compounds may be combined with other therapeutic agents for the treatment of one or more sleep disorders, depression, psychosis, dyskinesias, and/or parkinson's disease or any combinations..
Intra-cellular Therapies, Inc.

Skin treatment devices with locking mechanisms

Devices, kits and methods described herein may be for wound healing, including the treatment, amelioration, or prevention of scars and/or keloids by applying and/or maintaining a pre-determined strain in an elastic skin treatment device that is then affixed to the skin surface using skin adhesives to transfer a generally planar force from the bandage to the skin surface. Applicators are used to apply and/or maintain the strains, and some of the applicators are further configured to provide at least some mechanical advantage to the user when exerting loads onto the skin treatment device..
Neodyne Biosciences, Inc.

Novel preparing ph dependent ultra small polymeric nanoparticles for topical and/or transdermal delivery

The invention provides a new method for preparing ultra-small polymeric-lipidic delivery nanoparticles (usdns) that were synthesized by a nanoprecipitation method followed by a layer-by-layer nanodeposition. The usdns particle size can be controlled between 5-25 mn and provides loading capacities of 22.12% to 72.08%.
Indagomed. Llc

Breathing assistance apparatus

A mask with cushion that has an outer film is disclosed. The film may be self-skinning or a film formed about or glued to the cushion body.
Fisher & Paykel Healthcare Limited

Portable medical treatment system and use

A medical treatment system including a treatment chamber, a source of an aqueous mist containing a medication, a source of an oxygen-enriched gas, and a control system adapted to alternately surround a human body part with a mist containing a medication and the oxygen enriched gas, which can be used to treat various skin disorders including infected lesions, bacterial infections such as acne (i.e. Propionibacterium acnes), fungal infections such as athlete's foot (i.e.
Wound Care, Inc.

Silicone-based composition for skin treatment

The present embodiments may relate to topically delivered compounded medications for the treatment of scar tissue, skin disorders, and/or other ailments. In one aspect, a transdermal cream or gel may provide for the effective administration of multiple medications simultaneously.
Cmpd Licensing, Llc

Pharmaceutical compositions comprising 7-(1h-imidazol-4-ylmethyl)-5,6,7,8-tetrahydro-quinoline for treating skin diseases and conditions

The present invention relates to a method for treating skin diseases and skin conditions in a patient in need thereof which comprises of administering a therapeutically effective amount of a pharmaceutical composition comprising a therapeutically effective amount of 7-(1h-imidazol-4-ylmethyl)-5,6,7,8-tetrahydro-quinoline, or its individual enantiomers or the tautomers thereof, or a pharmaceutically acceptable salt thereof.. .
Allergan, Inc.

System for continuous monitoring of body sounds

A wearable monitoring system includes a microelectromechanical (mems) microphone to receive acoustic signal data through skin of a user. An integrated circuit chip is bonded to and electrically connected to the mems microphone.
International Business Machines Corporation

Method for selecting and controlling second work process during first work process in multitasking mobile terminal

Provided is a method for controlling a plurality of work processes in a multitasking mobile terminal, and more particularly, a method for selecting a second work process during a first work process and controlling a predetermined function of the selected second work process. In the controlling method, icons corresponding to the respective work processes are displayed in response to a user command, and a desired work process is selected through the displayed icons.
Pantech Inc.

Mir-21-3p inhibitors in skin disorders

The present invention is related to mir-21-3p inhibitors, which are particularly useful in the prevention and/or treatment of skin disorders.. .
Universite De Lausanne

Compositions and methods for treating bone, joints and cartilage

Briefly stated, the present invention provides compositions and methods for treating or preventing joint injuries utilizing hair follicle derived non-bulbar dermal sheath (“ndbs”) cells. Within one aspect of the invention methods are provided for isolating nbds cells, comprising the steps of: (a) preparing vital hair; (b) cleaving the hair prepared in step (a) to remove the hair follicle bulb; (c) isolating non-bulbar dermal sheath tissue; and (d) cultivating the isolated non-bulbar dermal sheath tissue to produce nbds cells.
Replicel Life Sciences Inc.

Microblister skin grafting

The present invention generally relates to devices for harvesting a skin graft(s). The present invention provides a blister raising device integrated with a member for cutting the blister..
Kci Licensing, Inc.

Imaging skin cancer detection device

The diagnostic methods of the invention are based on external imaging of lesions combined with an image taken with sub skin illumination revealing under the skin structures. A combination of the two images increases the available data, offering a better diagnostic tool..

Skin treatment apparatus

A skin treatment apparatus, preferably an epilator, comprising at least one detector for detecting approximation and/or contact with the skin and a control unit to actuate the device depending on the signal received from the detector. The control unit has at least one regulator which increases the speed of the drive unit upon detection of an increased resistance and/or current consumption by a sensor and/or decreases the speed of the drive unit upon detection of an decreased resistance and/or current consumption by a sensor..
Braun Gmbh

Skinning knife with removable blade

A skinning knife includes a handle and a blade carrier coupled to the handle, the blade carrier including a mount having a mounting surface, a boss extending outward from the mounting surface, and a spring including a front portion, a middle portion, and a rear portion. The skinning knife also includes a blade including a sharpened edge, a body, and a slot formed through the body, where the slot extends in a longitudinal direction from a front end to a rear end and includes a narrow portion of a first width and a wide portion of a second width greater than the first width.
Fiskars Brands, Inc.

Synergistic antimicrobial preparations containing chlorite and hydrogen peroxide

An anti-microbial preservative for use in ophthalmic and dermatologic products. The preservative includes from about 0.005 wt.
S.k. Pharmaceuticals, Inc.

Hand recognizing method, system, and storage medium

Disclosure is a hand recognizing method including: acquiring a binary image into which an image is segmented based upon the skin color of a human body; extracting a connectivity domain in the binary image as a connectivity domain to be recognized; calculating a feature vector of a corresponding sample of the connectivity domain to be recognized; calculating the distances between the feature vector of the connectivity domain to be recognized, and feature vectors of hand sample connectivity domain, and the distances between the feature vector of the connectivity domain to be recognized, and feature vectors of non-hand sample connectivity domains; obtaining k samples with the shortest distances, determining whether the number of hand samples among the k samples is more than the number of non-hand samples, and if so, then determining that the connectivity domain to be recognized is a hand feature, wherein k represents a positive odd number.. .
Le Shi Zhi Xin Electronic Technology (tian Jin) Limited

Systems and methods for distinguishing facial features for cosmetic application

A media editing device obtains a digital image, and a facial region of an individual in the digital image is identified by a facial region analyzer. A plurality of facial features of the facial region is identified by a facial feature identifier.
Perfect Corp.

Dynamic data masking of post-output database data

Dynamic data masking by intercepting data derived from a database, creating a tabular representation of the data, and masking any of the data in accordance with a masking policy that specifies which of the data are to be masked if a masking condition is met, where the masking condition references the tabular representation of the data using a tabular positional reference.. .
International Business Machines Corporation

Method and composition for treating cancer or skin lesion using a vaccine

A method for treating or reducing the incidence of recurrence of cancer, benign tumors or hpv-associated lesions, including skin cancer, and particularly squamous cell carcinoma (scc and basal-cell carcinoma, by administering one or more doses of hpv recombinant vaccine to a patient.. .
Hpvvax, Llc

Topical formulation for skin care

Disclosed herein is a method of preparing a subject's cells for topical treatment of a subject in need. Also provided is a topical formulation and methods of treating a subject suffering a skin disorder and pain using the topical formulation.
Aesthetics Biomedical, Inc.

Pharmaceutical formulations for treating skin disorders and methods for fabricating and using thereof

Pharmaceutical compositions for treating, mitigating or preventing inflammatory skin diseases, disorders and/or pathologies are described, the compositions comprising a tetracycline-class antibiotic(s), omega fatty acid(s), and/or nicotinic acid or derivatives thereof. Methods for fabricating the compositions and using them are also described..
Imprimis Pharmaceuticals, Inc.

Corticosteriod containing foam compositions and manufacture thereof

The present invention provides a method of manufacturing foamable, corticosteroid containing compositions as well as methods for treating various skin diseases.. .
Therapeutics Inc.

Halobetasol foam composition and use thereof

The present invention provides a composition and method for treating various skin diseases. The composition is formulated as a foamable composition and includes the corticosteroid halobetasol..
Therapeutics Inc.

Heteroaromatic compounds and their use as dopamine d1 ligands

And pharmaceutically acceptable salts thereof and n-oxides thereof; processes for the preparation of; intermediates used in the preparation of; and compositions containing such compounds (n-oxides thereof or or pharmaceutically acceptable salts of the compound or the n-oxides) and the uses of such compounds (n-oxides thereof or or pharmaceutically acceptable salts of the compound or the n-oxides) for the treatment of d1-mediated (or d1-associated) disorders including cognitive and motivational impairments and negative symptoms associated with illnesses such as schizophrenia, depression, bipolar disorder, parkinson's disease, mild cognitive impairment (mci), alzheimer's disease, lupus, huntington's disease, parkinson's, dyskinesia, adhd, post-traumatic stress disorder, autism spectrum disorder, treatment-resistant depression, major depressive disorder (mdd), drug dependence, tourette's syndrome, tardive dyskinesias as well as impairments associated with age, chronic stress, sleep deprivation, combat, chronic fatigue; endocrine or metabolic diseases such as hyperglycemia, dislipidemia, diabetes, obesity, and sepsis; and cardiovascular disorder such as hypertension. The present invention further provides a d1 agonist with reduced d1r desensitization, a d1 agonist with a reduced β-arrestin recruitment activity relative to dopamine, a d1 agonist interacting significantly with the ser188 but not significantly with the ser202 of a d1r when binding to the d1r, a d1 agonist interacting less strongly the asp103 and interacting less strongly with the ser198 of a d1r when binding to the d1r, and their uses..

Complexes of sirolimus and its derivatives, process for the preparation thereof and pharmaceutical compositions containing them

The invention is directed to a stable complex with controlled particle size, increased apparent solubility and increased dissolution rate comprising as active compound sirolimus or derivatives thereof, which is useful in the prophylaxis of organ rejection in patients receiving renal transplants, in the treatment of psoriasis, facial angiofibromas associated with tuberous sclerosis, fibrofolliculomas found in birt-hogg-dubé syndrome, chronic erosive oral lichen planus, early stage cutaneous t-cell lymphoma, treatment of autoimmune active anterior uveitis, dry eye syndrome, age-related macular degeneration, diabetic macular edema, noninfectious uveitis, telangiectasia, inflammatory skin diseases (dermatitis, including psoriasis and lichen ruber planus), pachyonychia congenita and in the suppression of angiogenesis pathways. More specifically, the complex of the present invention possesses increased apparent solubility, permeability and enhanced biological performance including significantly improved exposure, earlier tmax, higher cmax and higher trough concentrations at 24 hours which will allow the reduction of the dose..
Druggability Technologies Ip Holdco Limited

Topical skin care formulations comprising plant extracts

Disclosed are methods of treating skin with topical skin compositions comprising at least one plant extract.. .
Mary Kay Inc.





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This listing is a sample listing of patent applications related to Skin for is only meant as a recent sample of applications filed, not a comprehensive history. There may be associated servicemarks and trademarks related to these patents. Please check with patent attorney if you need further assistance or plan to use for business purposes. This patent data is also published to the public by the USPTO and available for free on their website. Note that there may be alternative spellings for Skin with additional patents listed. Browse our RSS directory or Search for other possible listings.


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