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Skin patents

      

This page is updated frequently with new Skin-related patent applications.




 Large area body shaping applicator patent thumbnailLarge area body shaping applicator
A method and apparatus that affect vacuum to massage a volume of the skin and one or more types of skin treatment energies coupled to the massaged volume to treat the skin and subcutaneous adipose tissue and produce a desired treatment effect. The method and apparatus are based on coupling an array or a number of arrays being an assembly of skin treatment units with each skin treatment unit including a hollow cavity and a number of different energy to skin applying elements operative to receive skin treatment energy from a source of such energy and couple or apply the received energy to a treated segment of skin..
Syneron Medical Ltd.


 Predicting allergic reactions patent thumbnailPredicting allergic reactions
This present invention provides a method of predicting immunogenicity and hypersensitivity or allergic reactions to chemical compounds, therapeutics, cosmetics and other chemical compositions. The method uses an in vitro assay employing autologous blood derived cells and an autologous cultured skin biopsy and is of particular utility in the identification and prediction of skin sensitizers that cause allergic contact dermatitis..
Alcyomics Ltd


 Antibodies, pharmaceutical compositions and methods patent thumbnailAntibodies, pharmaceutical compositions and methods
Pharmaceutical composition comprising antibodies or antigen binding fragments thereof that bind to stage-specific embryonic antigen 4 (ssea-4) are disclosed herein, as well as methods of use thereof. Methods of use include, without limitation, cancer therapies and diagnostics.
Obi Pharma, Inc.


 Auto-injector systems and  delivering cyst medication on demand patent thumbnailAuto-injector systems and delivering cyst medication on demand
An auto-injector device including a syringe, a needle arranged in the vicinity of a first end of the syringe, and a plunger arranged within the syringe. A volume within the syringe between the plunger the needle accommodates medicine, such that movement of the plunger toward the needle dispenses medicine through the needle.

 Compositions and methods for the treatment of photoaging and other conditions patent thumbnailCompositions and methods for the treatment of photoaging and other conditions
Compositions and methods for the treatment of skin disorders or disease are provided.. .
Pro Transit Nanotherapy Llc


 Therapeutic or prophylactic agent for itching skin diseases patent thumbnailTherapeutic or prophylactic agent for itching skin diseases
An antimicrobial peptide ll-37 has an action to promote expression of a nerve repulsion factor sema3a. Ll-37 is a peptide composed of the c-terminal 37 residues of human cathelicidin hcap18.
Toray Industries, Inc.


 Topical retinoid compositions patent thumbnailTopical retinoid compositions
The present application relates to topical compositions. In particular, the present application relates to a topical composition comprising retinoid as active agent, and pharmaceutically acceptable excipient(s), and a process of preparing such compositions.
Dr. Reddy's Laboratories, Ltd.


 Device and  treating a skin lesion patent thumbnailDevice and treating a skin lesion
An electronic device for treating a skin lesion by destroying an affected skin cell using an electric current includes a hollow cylindrical housing with a female casing configured to mate with a male casing via a threading. Further, a printed circuit board is housed within the hollow cylindrical housing and is configured to generate electric current by using a battery.

 System and  continuing playback in widget after app is backgrounded patent thumbnailSystem and continuing playback in widget after app is backgrounded
This disclosure generally relates to systems and methods that facilitate transitioning a current playback of a video in a video application to a video widget when the video application is moved to a background of a multitasking operating system in which the video application is executing. The transition occurs seamlessly at a point of the current playback in the video application when the video application is moved to the background.
Google Inc.


 Method and electronic device for positioning the center of palm patent thumbnailMethod and electronic device for positioning the center of palm
The present invention provides a method and electronic device for palm center positioning, wherein the method for palm center positioning includes the following steps: firstly, acquires an image including a palm and an arm; then acquiring a connection area of the palm and the arm in the image based on skin color feature in the image; subsequently acquiring an exterior contour of the connection area, and clearly defining boundary of the connection area to eliminate errors; and finally acquiring palm center position information according to a maximum value of the shortest distance from each pixel point in the connection area within the exterior contour to the exterior contour. This disclosure is characterized by simple steps and high positioning accuracy..
Le Shi Zhi Xin Electronic Technology (tianjin) Limited


Methods and materials for identifying metastatic malignant skin lesions and treating skin cancer

This document provides methods and materials for identifying metastatic malignant skin lesions (e.g., malignant pigmented skin lesions). For example, methods and materials for using quantitative pcr results and correction protocols to reduce the impact of basal keratinocyte contamination on the analysis of test sample results to identify metastatic malignant skin lesions are provided.
Mayo Foundation For Medical Education And Research

Methods of treating skin disorders using anti-il-31ra antibodies

The present invention relates to methods of treating patients suffering from contact dermatitis, drug induced delayed type cutaneous allergic reactions, toxic epidermal necrolysis, cutaneous t cell lymphoma, bullous pemphigoid, alopecia aereata, vitiligo, acne rosacea, prurigo nodularis, scleroderma, herpes simplex virus, or combination by administering an il-31ra antagonist.. .
Zymogenetics, Inc.

Therapeutic agent for motor disorders

Provided are an agent for the treatment and/or prophylaxis of a movement disorder, the agent for the treatment and/or prophylaxis wherein the movement disorder is extrapyramidal syndrome, the agent for the treatment and/or prophylaxis wherein the movement disorder is bradykinesia, gait disturbance, dystonia, dyskinesia or tardive dyskinesia, the agent for the treatment and/or prophylaxis wherein the movement disorder is a side effect of l-dopa and/or dopamine agonist therapy, and the like, each containing a thiazole derivative represented by the formula (i) wherein r1 represents aryl and the like, and r2 represents pyridyl or the like, or a pharmaceutically acceptable salt thereof as an active ingredient.. .
Kyowa Hakko Kirin Co., Ltd.

N-pyridinyl acetamide derivatives as inhibitors of the wnt signaling pathway

Disclosed are compounds useful as inhibitors of the wnt signalling pathway. Specifically, inhibitors of porcupine (porcn) are contemplated by the invention.
Redx Pharma Plc

Allosteric modulators of nicotinic acetylcholine receptors

The present disclosure relates to compounds of formula i that are useful as modulators of α7 nachr, compositions comprising such compounds, and the use of such compounds for preventing, treating, or ameliorating disease, particularly disorders of the central nervous system such as cognitive impairments in alzheimer's disease, parkinson's disease, and schizophrenia, as well as for l-dopa induced-dyskinesia and inflammation. .
Merck Sharp & Dohme Corp.

Uses of mesembryanthemum crystallinum l. callus extract in delaying skin cell aging, nursing skin, treating and preventing skin cancer

Use of mesembryanthemum crystallinum l. Callus extract in the manufacture of a medicament or a skin care product, wherein the medicament or skin care product is for at least one of delaying skin cell aging, nursing skin, repairing skin, treating skin cancer, and preventing skin cancer..
Tci Co., Ltd.

Wound fluid elevated protease enzyme inhibition through camelid blood products

Camelid blood products their peptide isolates and synthetic sequences for wound fluid elevated protease enzyme inhibition. The present invention provides evidence that metalloprotease and other protease enzyme (e.g.

Skin tag remover

The present invention is a skin tag remover which includes a cord formed into a loop at a tag end for placing around a skin tag, a cord housing for receiving a portion of the cord there through and a finger ring attached to a ring end of the cord. Pulling on the finger ring tightens the loop around the skin tag and places the cord into a constricted position so that blood flow is restricted to the skin tag.

Conjugates of ph low insertion peptide and monomethyl auristatins in the treatment of solid tumors

Constructs comprising ph low insertion peptide and variants thereof conjugated to monomethyl auristatins and analogs thereof are described. These constructs are useful, for example, in the treatment of solid tumors, including the treatment of breast cancer and prostate cancer, as well as other cancers such as pancreatic cancer, ovarian cancer, cervical cancer, uterine cancer, lung cancer, skin cancer, kidney cancer, and colon cancer.
Lehigh University

Benzoxazinone derivatives for treatment of skin diseases

The present invention relates to methods and compositions for inhibiting the activity of skin proteases, especially human kallikrein 7 (klk7), human kallikrein 5 (klk5), and human kallikrein 14 (klk14). More specifically, the invention relates to the use of substituted 3,1-benzoxazin-4-ones being selective inhibitors of human skin kallikreins for the treatment of skin diseases, more specifically for the treatment of inflammatory skins diseases, especially netherton syndrome..
Sixera Pharma Ab

Skin treatment method and apparatus

The application discloses a number of methods and apparatuses suitable for selective skin treatment have been described. In one example, a pair of rf electrodes is applied to skin.
Candela Corporation

Apparatus for forming delivery path for composition for treatment and auxiliary assembly for skin treatment including same

The present invention relates to an apparatus for forming a delivery path for a composition for treatment and an auxiliary assembly for skin treatment including the same, and provides an apparatus for forming a delivery path for a composition for treatment and an auxiliary assembly for skin treatment including the same, the apparatus comprising: a light source; a light irradiating unit for receiving a light from the light source to irradiate the light on a surface of skin; and a control unit for controlling a pulse waveform of a light irradiated through the light irradiating unit so as to form a plurality of pores, which form a path through which a composition applied on the surface of the skin is transferred inside, on the surface of the skin after irradiating the light.. .
Lutronic Corporation

Devices and methods for skin treatment

According to some embodiments, a system for treating skin includes a handpiece assembly comprising a tip and a main body portion, the main body portion comprising an interior cavity and at least one canister configured to store at least one of a treatment material and a waste material. The treatment material and/or the waste material is in fluid communication with the tip..
Edge Systems Llc

Topical formulation for skin care

Disclosed herein is a method of preparing a subject's cells for topical treatment of a subject in need. Also provided is a topical formulation and methods of treating a subject suffering a skin disorder and pain using the topical formulation.
Aesthetics Biomedical, Inc.

Acetic acid and hypochlorous acid compositions for treatment of biofilms and wound care

Disinfecting compositions containing hypochlorous acid and acetic acid are useful for treating biofilms in or on tissue, including biofilms related to wounds or other skin trauma. The compositions are useful for treating a variety of types of tissue, both on the surface on beneath the surface of tissue.
Softox Solutions As

Pharmaceutical compositions for combination therapy

This invention relates to novel pharmaceutical compositions comprising a therapeutically effective combination of a dopaminergic stabilizer known as pridopidine, and an inhibitor of the vesicular monoamine transporter type 2 (vmat) known as tetrabenazine. The pharmaceutical compositions for use according to the invention are contemplated particularly useful for improving the symptomatic therapeutic effects, and for reducing the adverse effects, of tetrabenazine in the treatment of movement disorders, and in particular movement disorders associated with huntington's disease, gilles de la tourette's syndrome, or tardive dyskinesia..
Teva Pharmaceuticals International Gmbh

Pluripotent stem cell for treating diabetic skin ulcer

The purpose of the present invention is to provide a novel medicinal use in regeneration medicine, said medicinal use comprising using pluripotent stem cells (muse cells). Provided is a cell preparation for treating skin ulcer, said cell preparation comprising ssea-3 positive pluripotent stem cells isolated from a mesenchymal tissue of a living organism or cultured mesenchymal cells.
Tohoku University

Topical formulations comprising a steroid

The application provides formulations for the topical administration of an active agent comprising at least one steroid, in the form of topical sprays that are propellant-free, and/or substantially non-foaming, and/or alcohol-free. The present application also provides processes for preparing such compositions and methods of using them in management of skin diseases or disorders such as psoriasis, dermatoses, and other associated skin diseases or disorders..
Dr. Reddy's Laboratories Ltd.

Topical skin care formulations comprising botanical extracts

Disclosed is a topical skin composition comprising an aqueous extract from a part of nymphaea gigantea, wherein said part consists of the flower of nymphaea gigantea, an aqueous extract from a part of plumeria alba, wherein said part consists of the flower of plumeria alba, and a dermatologically acceptable vehicle.. .
Mary Kay Inc.

Luminate face lotion

The present invention features novel cosmetic skin care compositions for improving the appearance of skin, particularly the reducing the appearance of age spots and discoloration.. .
Jan Marini Skin Research

Modular device and data management system and gateway for a communications network

A gateway provides duplex-directional, multimedia ad hoc mesh networking, peer-to-peer direct communications, power optimization, dynamic configuration, and data management, while operating within various devices and network topologies. A multitasking virtual machine monitor for mobile networked devices, that is capable of functional expandability and portability to various operating environments, interoperability with a variety of operating systems, the gateway control system (gcs) performs functional capabilities in both a local and a networked topology using local and remote hardware and software.
Eyecam, Llc

Coating composition comprising anti-skinning agent

The invention relates to a coating composition comprising an oxidatively drying binder and an anti-skinning agent, the anti-skinning agent comprising: a) a diketone of formula (i) (b) an aldoxime or ketoxime of formula (ii) wherein r1, r2, r3, r4 and n have the same meaning as that defined by the present application.. .
Ppg Europe B.v.

Low intensity magnetic field device for cosmetic skin treatment

Devices and methods for cosmetic skin treatment using a magnetic field are provided. A device can include a case, a stimulation head coupled with the case and including at least one coil of conductive wire for generating a magnetic field, and an electronic circuit housed in the case for driving the coils to generate the magnetic field..
The Florida International University Board Of Trustees

Topical skin compositions for treating wrinkles

Disclosed is a method for reducing the appearance of a wrinkle on skin comprising topically applying to said wrinkle a composition that includes an effective amount of ornithine, retinol, commiphora mukul resin or an extract thereof, and hyaluronic acid, wherein topical application of the composition reduces the appearance of said wrinkle within 120 seconds after application of the composition, and wherein topical application of said composition stimulates adipogenesis in said skin.. .
Mary Kay Inc.

A light-based collagen measurement system and a skin treatment system

A measurement system for light-based measurement of collagen, using a first light intensity and a second light intensity according to the invention, compromises a light source (120) for emitting a light beam having a source wavelength range and an optical system (130) to polarize light within the source wavelength range, thereby generating a polarized light beam (140), and to direct and focus the polarized light beam (140) to a target position inside the skin (160) at a predetermined focus depth below an outer surface of the skin. The measurement system further comprises a first detector (150) and a second detector.
Koninklijke Philips N.v.

Methods and systems for controlling or tuning the electric field generated in skin or tissue during cold plasma skin treatments

Exemplary systems and methods associated with skin treatments using non-thermal plasma to porate skin or tissues using conductive elements to direct an electric field through targeted regions of the skin or tissue. Various configurations of conductive elements and associated circuitry may be used to tune and control the electric field..
Ep Technologies Llc

Compositions and methods for treatment of pre-cancerous skin lesions

The present disclosure encompasses compositions and methods for the treatment of precancerous skin lesions. Compositions of the invention comprise a cytotoxic agent and a thymic stromal lymphopoietin (tslp) inducer..
Washington University

Topical healing and scar treatment composition

Topical aqueous compositions are effective in minimizing scar formation and improving the visual appearance of scars. The compositions are also effective in treating numerous skin disorders, including acne, psoriasis, and eczema..

Compositions of bioactive fulvate fractions and uses thereof

Compositions with fulvate fractions alone or in combination with growth factors, bioactive fragmented peptides, or combinations thereof are disclosed herein. Also disclosed are methods of using said compositions for the catalyzing cellular regeneration, including the healing, treatment, or prevention of skin disorders.
Omni Bioceutical Innovations, Inc.

Novel d3 dopamine receptor agonists to treat dyskinesia in parkinson's disease

The present invention provides a method of inhibiting, suppressing or preventing levodopa-induced dyskinesia in a patient suffering from parkinson's disease, comprising the step of administering to the patient a pharmaceutical composition comprising at least one compound of the invention. The present invention further provides a method of inhibiting, suppressing or preventing parkinson's disease in a patient, comprising the step of administering to the patient a pharmaceutical composition comprising at least one compound of the invention..
Rutgers, The State University Of New Jersey

Appliance for treatment of facial skin conditions

A mask member which fits over a portion of the face of a user. A retaining member holds the mask in place on the user's head.
L'oreal

Squeezable nail treatment container

An apparatus is provided for providing nail or skin treatment. The apparatus includes a container, formed of a compressible material; an insert, disposed within the container formed of a compressible material, and configured to receive and surround at least one body part of the user; and an opening at a first end of the container which provides access to an interior surface of the insert, wherein the insert is configured to hold at least one substance configured to treat at least one of a nail and skin of the user..
L'oreal

Systems and methods for presenting and interacting with a picture-in-picture representation of video content on an electronic device with a touch-sensitive display

Systems and methods for multitasking using touch-sensitive devices are disclosed herein. In one aspect, a method includes: playing video content in a full-screen mode on a touch-sensitive display of an electronic device.
Apple Inc.

Structure-preserving composite model for skin lesion segmentation

A structure-preserving composite model for skin lesion segmentation includes partitioning a dermoscopic image into superpixels at a first scale. Each superpixel is a vertex on a graph defined by color coordinates and spatial coordinates, and represents a number of pixels of the dermoscopic image according to the first scale.
International Business Machines Corporation

Systems and methods for activating a multi-tasking mode using an application selector that is displayed in response to a swipe gesture on an electronic device with a touch-sensitive display

Systems and methods for multitasking using touch-sensitive displays are disclosed. An example method includes: displaying a first application on a touch-sensitive display (tsd) of an electronic device; detecting, via the tsd, a swipe gesture that moves over part of the first application; in response to detecting the swipe gesture, displaying an application selector with a set of affordances, and the application selector is (i) displayed in a predefined portion of the tsd and (ii) overlays at least a portion of the displayed first application; detecting an input at an affordance of the set of affordances; in response to detecting the input: (i) ceasing to display the application selector; (ii) displaying a second application corresponding to the selected affordance in the predefined portion that was previously used to display the application selector; and (iii) resizing the first application to occupy a remaining portion of the tsd adjacent to the predefined portion..
Apple Inc.

Presence of phosphorylated tau protein in the skin of neurodegenerative disease and scis, scc, and bcc

The presence of misfolded proteins in the brain is the hallmark of neurodegenerative diseases. Protein aggregates could have systemic expression and might be found in several tissues including the skin.

Modulating gamma-c-cytokine activity

Peptide antagonists of γc-family cytokines, which is associated with important human diseases, such as leukemia, autoimmune diseases, collagen diseases, diabetes mellitus, skin diseases, degenerative neuronal diseases and graft-versus-host disease (gvhd). Thus, inhibitors of γc-cytokine activity are valuable therapeutic and cosmetic agents as well as research tools.
Bioniz, Llc

Chemical inhibitors of sebocyte function

The present discovery pertains to the discovery of certain amphiphilic compounds that may be useful for the management of sebum secretion in subjects with acne, oily skin, or seborrheic dermatitis. These compounds are 1-dialkylphosphorylalkanes with the longest alkyl group being seven or more carbons.

Systems and methods for skinning articles

A system for delivering and applying a flowable mixture to an article (311-313) is disclosed. The system includes a mixture delivery system (200) and a skinning system (300).
Corning Incorporated

Compositions and methods comprising extracts of zingiberaceae

The present technology relates to compositions, in particular, cosmetic, topical and pharmaceutical compositions, comprising extracts of plants in the family zingiberaceae, as well as methods in connection with such compositions, including methods of reducing sebum production, reducing the appearance of oily skin, reducing the appearance of acne, reducing the appearance of pores, reducing the appearance of wrinkles, reducing free radicals, reducing baldness, reducing or increasing hair growth and reducing or increasing androgenic stimulation, or reducing the rate of oxidation.. .
Biocogent, Llc

Method for treating skin cancer

A method for treating skin cancer including the steps of applying an isothiocyanate functional surfactant to an area affected by skin cancer, wherein the isothiocyanate functional surfactant comprises at least one isothiocyanate functional group associated with an aliphatic and/or aromatic carbon atom of the isothiocyanate functional surfactant.. .

Toxic aldehyde related diseases and treatment

The present invention provides for the treatment, prevention, and/or reduction of a risk of a disease, disorder, or condition in which aldehyde toxicity is implicated in the pathogenesis, including ocular disorders, skin disorders, conditions associated with injurious effects from blister agents, and autoimmune, inflammatory, neurological and cardiovascular diseases by the use of a primary amine to scavenge toxic aldehydes, such as mda and hne.. .
Aldeyra Therapeutics, Inc.

Immune regulatory oligonucleotide (iro) compounds to modulate toll-like receptor based immune response

The invention provides novel immune regulatory oligonucleotides (iro) as antagonist of tlrs and methods of use thereof. These iros have unique sequences that inhibit or suppress tlr-mediated signaling in response to a tlr ligand or tlr agonist.
Idera Pharmaceuticals, Inc.

Cancer therapeutics

This invention relates to compounds that bind to wild-type cbfβ and inhibit cbfβ binding to runx proteins. The potent compounds of the invention inhibit this protein-protein interaction at low micromolar concentrations, using allosteric mechanism to achieve inhibition, displace wild-type cbfβ from runx1 in cells, change occupancy of runx1 on target genes, and alter gene expression of runx1 target genes.
University Of Virginia Patent Foundation

Apparatus and skinning articles

A skinning apparatus and a method of skinning a porous ceramic. The apparatus includes an axial skinning manifold.
Corning Incorporated

Methods of use for 2,5-dihydroxybenzene sulfonic acid compounds for the treatment of cancer, rosacea and psoriasis

The invention describes compositions and methods of use for 2,5-dihydroxybenzene sulfonic acid compounds and pharmaceutically acceptable salts thereof. The invention provides methods for (a) treating skin cancer; (b) treating cancer of the organs; (c) treating leukemia; (d) improving the efficacy of chemotherapy, radiation therapy and/or cancer immunotherapy; (e) treating rosacea; and (f) treating psoriasis by administration of a composition comprising at least one 2,5-dihydroxybenzene sulfonic acid compound or a pharmaceutically acceptable salt thereof, and, optionally at least one therapeutic agent.
Amderma Pharmaceuticals, Llc

Hybrid mobile interactions for native apps and web apps

There is disclosed a system, including apparatus, methods and computer programs, for running native software applications (apps) and html5 web-based apps on a computing device, particularly a mobile computing device, in a multitasking mode of operation. In one embodiment, touch screen displays having one or more browsers are adapted to run one or more html5 apps, and receive input from hand gestures.
Intel Corporation

General-purpose reconfigurable conduit and reaction chamber microfluidic arrangements for lab-on-chip and miniature chemical processing

A general-purpose software-reconfigurable chemical process system useful in a wide range of applications is disclosed. Embodiments may include software control of internal processes, automated provisions for cleaning internal elements with solvents, provisions for clearing and drying gasses, and multitasking operation.

Methods, compositions and apparatuses for treating psoriasis by phototherapy

Compositions, methods and apparatuses for phototherapy to treat skin disorders. In particular, described herein are methods, compositions, phototherapy dressings for use with phototherapy uv light applicators (sources) and phototherapy uv light applicators to treat skin disorders such as psoriasis..

Devices and methods for treating the skin using a porous member

According to some embodiments, a skin treatment assembly comprises a tip comprising a proximal end and a distal end, a container configured to secure to the tip along the proximal end of the tip, wherein the container is configured to contain a liquid, and a porous member configured to extend at least partially within an interior of the container such that it contact a liquid contained within the container, wherein the porous member is configured to extend at least partially within an interior of the tip and is configured to facilitate the transfer of liquid from the container to the distal end of the tip.. .
Edge Systems Llc

Hydrogels for treating and ameliorating wounds and methods for making and using them

In alternative embodiments, provided are compositions, e.g., pharmaceutical compositions, formulations, kits and other products of manufacture, comprising a hydrogel and active ingredients, including mixed thickness skin micrografts, or full or split-thickness skin grafts, contained or mixed in or within the hydrogel; and methods for making and using them. In alternative embodiments, compositions and methods as provided herein are used for the treatment or amelioration of wounds and surgical sites, and include compositions and methods for micrografting, or for micrografting a wound, or for micrografting a wound for rapid re-epithelialization, or for micrografting a wound for rapid re-epithelialization of large non-healing wounds..
Vicus Therapeutics, Llc

Phospholipid-containing marine extracts for treatment of cardiovascular diseases

The present invention relates to a method of treatment and/or prevention of cardiovascular disease, rheumatoid arthritis, skin cancer, premenstrual syndrome, diabetes and transdermal transport enhancement. The method comprises the administration of a therapeutically effective amount of krill and/or marine oil to a patient.
Neptune Technologies & Bioressources, Inc.

Method for avoiding or inhibition of dyskinesia

Certain neurological disorders are treated with dopamine agonists (e.g. L-dopa) but these treatments unintentionally cause levodopa-induced dyskinesias (lids) or tardive dyskinesia.
Research Foundation Of The City University Of New York

Compositions for nail and skin treatment

Novel topical compositions for the treatment of nail and skin afflictions comprising at least one active agent, at least one volatile solvent, at least one film-forming ingredient and at least one phospholipid, processes for their preparation and methods of treatment of nail and skin afflictions. Following application of the compositions and evaporation of volatile solvents, the composition produces a film, which has web-like structures containing the active agent(s)..
Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd

Protective skin compositions

The subject of the present invention is cosmetic or pharmaceutical compositions which are protective against common skin irritants or allergens. The invention is also directed to the use of these compositions to protect skin from the effects of metal.
Amantin Experts

Methods for preparing a skin graft

The present invention generally relates to methods for applying a skin graft. Methods of the invention involve harvesting an epidermal skin graft, and applying the epidermal skin graft to a recipient site such that the basal layer of the skin graft makes direct contact with the recipient site..
Kci Licensing, Inc.

Optical transfer diagnosis for detection and monitoring of tissue disorders

Systems and methods for discriminating between malignant and benign pigmented skin lesions based on optical analysis using spatial distribution maps, morphological parameters, and additional diagnostic parameters derived from images of tissue lesions. A handheld optical transfer diagnosis device is disclosed capable of capturing a series of reflectance images of a skin lesion at a variety of angles of illumination and observation..
Balter, Inc.

Method and electronic displaying reference locations for locating ecg pads and recording medium using the method

A method and an electronic apparatus for displaying reference locations for locating ecg pads and a recording medium using the method are provided. In the method, a body image is retrieved and a skin area in accordance with a skin color in the body image is detected.
Htc Corporation

N-(4-hydroxy-4-methyl-cyclohexyl)-4-phenyl-benzenesulfonamides and n-(4- hydroxy-4-methyl-cyclohexyl)-4-(2-pyridyl)benzenesulfonamides and their therapeutic use

The present invention pertains generally to the field of therapeutic compounds. More specifically the present invention pertains to certain substituted n-(4-hydroxy-4-methyl-cyclohexyl)-4-phenyl-benzenesulfonamide and n-(4-hydroxy-4-methyl-cyclohexyl)-4-(2-pyridyl)benzenesulfonamide compounds (collectively referred to herein as hmc compounds) that are useful, for example, in the treatment of disorders (e.g., diseases) including, inflammation and/or joint destruction and/or bone loss; disorders mediated by excessive and/or inappropriate and/or prolonged activation of the immune system; inflammatory and autoimmune disorders, for example, rheumatoid arthritis; psoriasis; psoriatic arthritis; chronic obstructive pulmonary disease (copd); asthma; atherosclerosis; inflammatory bowel disease; ankylosing spondylitis; multiple sclerosis; systemic lupus erythematosus; sjogren's syndrome; a disorder associated with bone loss, such as bone loss associated with excessive osteoclast activity in rheumatoid arthritis, osteoporosis, cancer-associated bone disease, or paget's disease; cancer, such as a haematological malignancy, such as multiple myeloma, leukemia, or lymphoma, or a solid tumour cancer, such as bladder cancer, breast cancer (female and/or male), colon cancer, renal cell carcinoma, kidney cancer, lung cancer, pancreatic cancer, gastric cancer, prostate cancer, brain cancer, skin cancer, thyroid cancer, basal cell ameloblastoma, or melanoma; a disorder associated with fibrosis, such as systemic sclerosis or scleroderma; or a rare vasculitide, such as behçet's disease.
Pimco 2664 Limited

Skin treatment device

The present invention is concerned with a skin treatment device, in particular a temporal hair removal device, having a light emission unit having a substrate, a plurality of first led dies mounted on the substrate on an area of at least 0.2 cm2, in particular of at least 1.0 cm2, where the first led dies are each arranged for emitting light at a first peak emission wavelength in the far red or infrared wavelength range of between 700 nm and 980 nm, and at least one second led die arranged for emitting light at a second peak emission wavelength in the visible wavelength range of between 400 nm and below 700 nm, wherein the skin treatment device is arranged to activate the first led dies to emit a treatment light pulse, the treatment light pulse in particular having a pulse length of between 10 ms and 300 ms, and the first led dies have a radiant flux such that a radiant fluence on the skin of a user of at least 1 j/cm2 is achieved by application of the treatment light pulse, and the skin treatment device is arranged to activate the at least one second led die to emit a visible light pulse simultaneously with the emission of the treatment light pulse.. .
Braun Gmbh

Fenestrated bone wrap graft

The present invention relates to a fenestrated bone wrap graft and a method of preparing cortical bone in thin sheets then fully demineralizing it to give it formed flexibility and then creating fenestrations in the cortical bone in a fashion similar to, but not identical to, skin grafts.. .
Vivex Biomedical, Inc.

Aldose reductase inhibitors and uses thereof

The present invention relates to novel compounds and pharmaceutical compositions thereof, and methods for promoting healthy aging of skin, the treatment of skin disorders, the treatment of cardiovascular disorders, the treatment of renal disorders, the treatment of angiogenesis disorders, such as cancer, treatment of tissue damage, such as non-cardiac tissue damage, the treatment of evolving myocardial infarction, and the treatment of various other disorders, such as complications arising from diabetes with the compounds and compositions of the invention. Other disorders can include, but are not limited to, atherosclerosis, coronary artery disease, diabetic nephropathy, diabetic neuropathy, diabetic retinopathy, infections of the skin, peripheral vascular disease, stroke, and the like..
The Trustees Of Columbia University In The City Of New York

Aldose reductase inhibitors and uses thereof

The present invention relates to novel compounds and pharmaceutical compositions thereof, and methods for promoting healthy aging of skin, the treatment of skin disorders, the treatment of cardiovascular disorders, the treatment of renal disorders, the treatment of angiogenesis disorders, such as cancer, treatment of tissue damage, such as non-cardiac tissue damage, the treatment of evolving myocardial infarction, and the treatment of various other disorders, such as complications arising from diabetes with the compounds and compositions of the invention. Other disorders can include, but are not limited to, atherosclerosis, coronary artery disease, diabetic nephropathy, diabetic neuropathy, diabetic retinopathy, infections of the skin, peripheral vascular disease, stroke, and the like..
The Trustees Of Columbia University In The City Of New York

Compounds, formulations, and methods for treating or preventing inflammatory skin disorders

Wherein each of b1, b2, and b3 is independently hydrogen, hydroxy, or alkoxy; and each of b4 and b5 is independently hydrogen or alkyl, applying such compounds topically as sprays, mists, aerosols, solutions, lotions, gels, creams, ointments, pastes, unguents, emulsions, and suspensions to treat inflammatory skin disorders and the symptoms associated therewith.. .

Skin compositions and uses

The present invention provides a skin care composition for maintaining or improving the healthy appearance of the skin of an individual and/or rejuvenate the skin of an individual. A skin care composition comprises active ingredients, including, without limitation, growth factors, anti-oxidants, curcuminoids, oils and/or red rice extracts.
Stemetrix, Inc.

Skin treatment device

The present invention is concerned with a skin treatment device, in particular a hair removal device, having a light emission unit comprising a substrate and a plurality of first led dies mounted on the substrate on an area of at least 0.2 cm2, in particular of at least 1 cm2, wherein the skin treatment device is arranged to activate the first led dies to emit a treatment light pulse having a pulse length in particular in the range of between 10 ms and 300 ms and the first led dies have a radiant flux such that a radiant fluence on the skin of a user of at least 1 j/cm2 is achieved by application of the treatment light pulse, wherein the light emission unit has at least two selectable active areas of first led dies, where the selectable active areas have different sizes, and at least three second led dies are mounted on the substrate at locations suitable for visibly indicating each of the selectable active areas.. .
Braun Gmbh

Propolis and extracts thereof for the treatment of skin cancers and improvement of skin health

This invention provides pharmaceutical and cosmeceutical compositions, including anti-skin cancer compositions, n containing propolis and cyclodextrin, and compositions comprising one or more compounds present in propolis, including compositions comprising one or more compounds present as an inclusion complex with cyclodextrin. Methods of using such compounds and compositions, in particular in the treatment or prevention of skin cancers and skin disorders, and in enhancing skin health, are also provided..
Manuka Health New Zealand Limited

Nitric oxide topical application apparatus and methods

A topical application of nitric oxide may be provided by two separate containers, each containing an active component media to produce nitric oxide when combined. For example, a nitrite component media may be contained in one dispenser and an acidified component media may be contained in another dispenser.
Syk Technologies, Llc

Silicone-based biophotonic compositions and uses thereof

The present disclosure provides silicone-based biophotonic compositions and methods useful in phototherapy. In particular, the silicone-based biophotonic compositions of the present disclosure include a silicone phase and a surfactant phase, wherein the surfactant phase comprises at least one chromophore solubilized in a surfactant.
Klox Technologies Inc.

Methods of chemical synthesis and purification of diaminophenothiazinium compounds including methylthioninium chloride (mtc)

This disclosure pertains generally to the field of chemical synthesis and purification, and more specifically to methods of synthesizing and purifying certain 3,7 diamino-phenothiazin-5-ium compounds (referred to herein as “diaminophenothiaziniumcompounds”) including methythioninium chloride (mtc) (also known as methylene blue). In one embodiment, the method comprises the steps of, in order: nitrosylation (nos); nitrosyl reduction (nr); thiosulfonic acid formation (tsaf); oxidative coupling (oc); cr(vi) reduction (cr); isolation and purification of zwitterionic intermediate (iapozi); ring closure (rc); chloride salt-formation (csf); one of: sulphide treatment (st); dimethyldithiocarbamate treatment (dt); carbonate treatment (ct); ethylenediaminetetraacetic acid treatment (edtat); organic extraction (oe); and recrystallisation (rx).
Wista Laboratories Ltd.

Selective serotonin 2a/2c receptor inverse agonists as therapeutics for neurodegenerative diseases

Behavioral pharmacological data with the compound of formula (i), a novel and selective 5ht2a/2c receptor inverse agonist, demonstrate in vivo efficacy in models of psychosis and dyskinesias. This includes activity in reversing mk-801 induced locomotor behaviors, suggesting that this compound may be an efficacious anti-psychotic, and activity in an mptp primate model of dyskinesias, suggesting efficacy as an anti-dyskinesia agent.
Acadia Pharmaceuticals Inc.

Biophotonic compositions comprising halogen and uses thereof

The present disclosure provides biophotonic compositions containing halogen ions and/or halogen salts and methods useful in phototherapy. In particular, the biophotonic compositions comprising halogen of the present disclosure include at least one chromophore; and halogens and/or halogen salts such ki, or kcl, or kbr, or csbr, or mgbr2, or znbr2, or naf, or nacl, or nabr, or i2, or i3−, or br2, or cl2.
Klox Technologies Inc.

Abrasive skin treatment device

An abrasive skin treatment device including a handle portion, a head portion including an exfoliating element, and a unitary pivoting mechanism providing relative movement between the handle portion and the head portion along at least two planes.. .
Telebrands Corp.

Abrasive skin treatment device

An abrasive skin treatment device including a handle portion, a head portion including an exfoliating element, and a unitary pivoting mechanism providing relative movement between the handle portion and the head portion along at least two planes.. .
Telebrands Corp.

Method and an providing a multitasking view

According to an aspect, there is provided a method and an apparatus for providing a multitasking view. Task information of a task executed on a first device and a preview image of the executed task is received.
Microsoft Technology Licensing, Llc

Method of designing a peptide and/or peptide derivative for modulating gamma-c-cytokine activity

The γc-family cytokines, interleukin-2 (il-2), interleukin-4 (il-4), interleukin-7 (il-7), interleukin-9 (il-9), interleukin-15 (il-15), and interleukin-21 (il-21), are associated with important human diseases, such as leukemia, autoimmune diseases, collagen diseases, diabetes mellitus, skin diseases, degenerative neuronal diseases and graft-versus-host disease (gvhd). Thus, inhibitors of γc-cytokine activity are valuable therapeutic and cosmetic agents as well as research tools.
Bioniz, Llc

Pharmaceutical composition for preventing or treating skin rash

Provided is a method for preventing or treating skin rash comprising administering to a subject in need thereof epidermal growth factor as an active ingredient. The skin rash includes a skin disorder caused by administering an epidermal growth factor receptor inhibitor, such as erlotinib, as an adverse event..
Dong-a University Research Foundation For Industry-academy Cooperation

Method for producing mycosporine-like amino acid using microbes

Provided are: a method for producing a mycrosporine-like amino acid (maa) that includes a step in which microbes are cultivated that produce maa on the outside of bacterial cells, a step in which the bacterial cells and extracellular culture fluid are separated, and a step in which the maa is recovered from the extracellular culture fluid; an maa indicated by formula (1), an maa produced using this method, or an ultraviolet-absorbing composition including the maa indicated by formula (1); and a composition including the maa produced using this method or the maa indicated by formula (1), for preventing at least one symptom or disease selected from a group comprising acute skin reactions, aging of the skin, and skin cancer.. .
Nagase & Co., Ltd.

Sensor inserter having introducer

Methods, device and system for providing a sensor insertion assembly including an inserter housing, an introducer including a body portion having a proximal end and a distal end and a shaft portion comprising a channel and a distal end, the shaft portion extending downwardly from an edge of the body portion, the shaft portion including a holding member disposed along a length of the channel, the holding member configured to substantially releasably retain a sensor, an on-body electronics unit, wherein the introducer is configured for insertion of the sensor through an aperture in the on-body electronics unit prior to insertion through skin and a drive mechanism included in the inserter housing and operatively coupled to the introducer, wherein the drive mechanism drives the introducer and retained sensor through the skin are provided.. .
Abbott Diabetes Care Inc.

Device, system, method and kit for preparing skin

A skin treatment device having a substrate having a first surface and a second surface, and an adhesive layer covering at least a portion of the first surface of the substrate. When the adhesive layer is applied to the skin surface of a mammal and removed, hair is removed at the follicle.
Full Power Aed, Llc

Nurr1 as a genetic target for treating levodopa-induced dyskinesias in parkinson's disease

Methods of treating movement disorders by reducing the activity of nurr1 are disclosed. These methods are particularly applicable to subjects suffering from parkinson's disease who have either developed levodopa-induced dyskinesia (lid) or are at risk of developing lid.
Board Of Trustees Of Michigan State University

Enantiomers of 8-hydroxyquinoline derivatives and the synthesis thereof

The subject matter of the invention furthermore relates to a novel, stereoselective synthesis for the preparation of the novel enantiomer derivatives according to the invention. The novel medicinal and/or pharmaceutical compositions comprising these enantiomers are suitable for the treatment of the named diseases, and the enanatiomers are used for manufacture of these compositions.

Skin lightening compounds

The present invention provides a compound of formula i, ii or iii or a salt or prodrug derivative thereof that is a skin-lightening agent useful for the inhibition of melanin synthesis and/or the removal of existing melanin to function as a skin-lightening agent.. .
Wisys Technology Foundation Inc.

Composition comprising gpcr19 agonist as an active ingredient for preventing or treating allergic dermatitis

The present invention is about a pharmaceutical composition, an oral preparation, and an injection preparation containing a g protein-coupled receptor19 (gpcr19) agonist, specifically sodium taurodeoxycholate(hy2191) and its derivative, as an active ingredient for preventing or treating allergic skin diseases. The present invention is also about an external preparation and a cosmetic composition containing said pharmaceutical composition for preventing and improving allergic skin diseases.
Shaperon Inc.

Method for evaluating condition of skin dryness

To provide a method for quickly and accurately evaluating a condition of skin dryness and a method for efficiently searching a substance to improve dry skin. A method for evaluating a condition of skin dryness, the method comprising measuring the expression levels of agr2 and/or agr3 in skin cells collected from subjects..
Kao Corporation

Methods of preparing materials with ammonia oxidizing bacteria and testing materials for ammonia oxidizing bacteria

This disclosure provides, inter alia, systems and methods for testing products for ammonia oxidizing bacteria, quality control, and providing products with ammonia oxidizing bacteria. The systems and methods herein may be used, inter alia, to treat diseases associated with low nitrite levels, skin diseases, and diseases caused by pathogenic bacteria..
Aobiome Llc

Urea and amide derivatives of aminoalkylpiperazines and use thereof

The compounds can be used for treating a patient suffering from a condition that is capable of treatment with a partial agonist or antagonist of the dopamine d2/d3 receptors. The compounds are especially useful for patients suffering from schizophrenia, depressions, neurodegenerative diseases such as parkinson's, dyskinesias, substance abuse and relapse to substance abuse and addiction to substances such as cocaine, methamphetamine, nicotine and alcohol, glaucoma, cognitive disorders, restless leg syndrome, attention deficit hyperactivity disorders, hyperprolactinemia, autism, motor disturbances such as akathisia, rigor, dystonias as well as various disorders of the urinary tract and other neurologic disorders.

Radio frequency skin treatment device

The invention relates to a device (1) for skin treatment comprising a non-circular symmetrical outer electrode and at least two inner electrodes (20; 22) surrounded by the outer electrodes. An rf generator (16) is arranged to supply an rf voltage between the inner electrodes and the outer electrode.
Koninklijke Philips N.v

Centrosymmetric radio frequency electrode configuration for skin treatment

The invention relates to a device (100) for rf skin treatment comprising an outer electrode (2) arranged on an operational side (15) of the device. The outer electrode has an annular or equilateral polygonal shape.
Koninklijke Philips N.v.

Hatching fluid enzymes and uses thereof

The present invention relates to various polypeptides from fish hatching fluid, their encoding nucleic acid sequences, pharmaceutical compositions comprising said polypeptides and nucleic acid molecules and their use in various medical and cosmetic applications to the skin, particularly for moisturizing skin and/or for exfoliation of the horny layer of the skin for treating or preventing skin disorders or conditions in an animal.. .
Aqua Bio Technology Asa

Systems and methods for storage and delivery of ammonia oxidizing bacteria

This disclosure provides, inter alia, systems and methods for storage and delivery of ammonia oxidizing bacteria, and preparations comprising ammonia oxidizing bacteria. The ammonia oxidizing bacteria may be provided in a container or a kit, with one or more other components that may enhance delivery.
Aobiome Llc

Methods and compositions for sleep disorders and other disorders

Use of particular substituted heterocycle fused gamma-carboline compounds as pharmaceuticals and pharmaceutical compositions comprising them for the treatment of one or more disorders involving the 5-ht2a, sert and/or dopamine d2 pathways are disclosed. In addition, the compounds may be combined with other therapeutic agents for the treatment of one or more sleep disorders, depression, psychosis, dyskinesias, and/or parkinson's disease or any combinations..
Intra-cellular Therapies, Inc.

Skin treatment devices with locking mechanisms

Devices, kits and methods described herein may be for wound healing, including the treatment, amelioration, or prevention of scars and/or keloids by applying and/or maintaining a pre-determined strain in an elastic skin treatment device that is then affixed to the skin surface using skin adhesives to transfer a generally planar force from the bandage to the skin surface. Applicators are used to apply and/or maintain the strains, and some of the applicators are further configured to provide at least some mechanical advantage to the user when exerting loads onto the skin treatment device..
Neodyne Biosciences, Inc.

Novel preparing ph dependent ultra small polymeric nanoparticles for topical and/or transdermal delivery

The invention provides a new method for preparing ultra-small polymeric-lipidic delivery nanoparticles (usdns) that were synthesized by a nanoprecipitation method followed by a layer-by-layer nanodeposition. The usdns particle size can be controlled between 5-25 mn and provides loading capacities of 22.12% to 72.08%.
Indagomed. Llc

Breathing assistance apparatus

A mask with cushion that has an outer film is disclosed. The film may be self-skinning or a film formed about or glued to the cushion body.
Fisher & Paykel Healthcare Limited

Portable medical treatment system and use

A medical treatment system including a treatment chamber, a source of an aqueous mist containing a medication, a source of an oxygen-enriched gas, and a control system adapted to alternately surround a human body part with a mist containing a medication and the oxygen enriched gas, which can be used to treat various skin disorders including infected lesions, bacterial infections such as acne (i.e. Propionibacterium acnes), fungal infections such as athlete's foot (i.e.
Wound Care, Inc.

Silicone-based composition for skin treatment

The present embodiments may relate to topically delivered compounded medications for the treatment of scar tissue, skin disorders, and/or other ailments. In one aspect, a transdermal cream or gel may provide for the effective administration of multiple medications simultaneously.
Cmpd Licensing, Llc

Pharmaceutical compositions comprising 7-(1h-imidazol-4-ylmethyl)-5,6,7,8-tetrahydro-quinoline for treating skin diseases and conditions

The present invention relates to a method for treating skin diseases and skin conditions in a patient in need thereof which comprises of administering a therapeutically effective amount of a pharmaceutical composition comprising a therapeutically effective amount of 7-(1h-imidazol-4-ylmethyl)-5,6,7,8-tetrahydro-quinoline, or its individual enantiomers or the tautomers thereof, or a pharmaceutically acceptable salt thereof.. .
Allergan, Inc.

System for continuous monitoring of body sounds

A wearable monitoring system includes a microelectromechanical (mems) microphone to receive acoustic signal data through skin of a user. An integrated circuit chip is bonded to and electrically connected to the mems microphone.
International Business Machines Corporation

Method for selecting and controlling second work process during first work process in multitasking mobile terminal

Provided is a method for controlling a plurality of work processes in a multitasking mobile terminal, and more particularly, a method for selecting a second work process during a first work process and controlling a predetermined function of the selected second work process. In the controlling method, icons corresponding to the respective work processes are displayed in response to a user command, and a desired work process is selected through the displayed icons.
Pantech Inc.

Mir-21-3p inhibitors in skin disorders

The present invention is related to mir-21-3p inhibitors, which are particularly useful in the prevention and/or treatment of skin disorders.. .
Universite De Lausanne

Compositions and methods for treating bone, joints and cartilage

Briefly stated, the present invention provides compositions and methods for treating or preventing joint injuries utilizing hair follicle derived non-bulbar dermal sheath (“ndbs”) cells. Within one aspect of the invention methods are provided for isolating nbds cells, comprising the steps of: (a) preparing vital hair; (b) cleaving the hair prepared in step (a) to remove the hair follicle bulb; (c) isolating non-bulbar dermal sheath tissue; and (d) cultivating the isolated non-bulbar dermal sheath tissue to produce nbds cells.
Replicel Life Sciences Inc.

Microblister skin grafting

The present invention generally relates to devices for harvesting a skin graft(s). The present invention provides a blister raising device integrated with a member for cutting the blister..
Kci Licensing, Inc.

Imaging skin cancer detection device

The diagnostic methods of the invention are based on external imaging of lesions combined with an image taken with sub skin illumination revealing under the skin structures. A combination of the two images increases the available data, offering a better diagnostic tool..

Skin treatment apparatus

A skin treatment apparatus, preferably an epilator, comprising at least one detector for detecting approximation and/or contact with the skin and a control unit to actuate the device depending on the signal received from the detector. The control unit has at least one regulator which increases the speed of the drive unit upon detection of an increased resistance and/or current consumption by a sensor and/or decreases the speed of the drive unit upon detection of an decreased resistance and/or current consumption by a sensor..
Braun Gmbh

Skinning knife with removable blade

A skinning knife includes a handle and a blade carrier coupled to the handle, the blade carrier including a mount having a mounting surface, a boss extending outward from the mounting surface, and a spring including a front portion, a middle portion, and a rear portion. The skinning knife also includes a blade including a sharpened edge, a body, and a slot formed through the body, where the slot extends in a longitudinal direction from a front end to a rear end and includes a narrow portion of a first width and a wide portion of a second width greater than the first width.
Fiskars Brands, Inc.

Synergistic antimicrobial preparations containing chlorite and hydrogen peroxide

An anti-microbial preservative for use in ophthalmic and dermatologic products. The preservative includes from about 0.005 wt.
S.k. Pharmaceuticals, Inc.

Hand recognizing method, system, and storage medium

Disclosure is a hand recognizing method including: acquiring a binary image into which an image is segmented based upon the skin color of a human body; extracting a connectivity domain in the binary image as a connectivity domain to be recognized; calculating a feature vector of a corresponding sample of the connectivity domain to be recognized; calculating the distances between the feature vector of the connectivity domain to be recognized, and feature vectors of hand sample connectivity domain, and the distances between the feature vector of the connectivity domain to be recognized, and feature vectors of non-hand sample connectivity domains; obtaining k samples with the shortest distances, determining whether the number of hand samples among the k samples is more than the number of non-hand samples, and if so, then determining that the connectivity domain to be recognized is a hand feature, wherein k represents a positive odd number.. .
Le Shi Zhi Xin Electronic Technology (tian Jin) Limited

Systems and methods for distinguishing facial features for cosmetic application

A media editing device obtains a digital image, and a facial region of an individual in the digital image is identified by a facial region analyzer. A plurality of facial features of the facial region is identified by a facial feature identifier.
Perfect Corp.

Dynamic data masking of post-output database data

Dynamic data masking by intercepting data derived from a database, creating a tabular representation of the data, and masking any of the data in accordance with a masking policy that specifies which of the data are to be masked if a masking condition is met, where the masking condition references the tabular representation of the data using a tabular positional reference.. .
International Business Machines Corporation

Method and composition for treating cancer or skin lesion using a vaccine

A method for treating or reducing the incidence of recurrence of cancer, benign tumors or hpv-associated lesions, including skin cancer, and particularly squamous cell carcinoma (scc and basal-cell carcinoma, by administering one or more doses of hpv recombinant vaccine to a patient.. .
Hpvvax, Llc

Topical formulation for skin care

Disclosed herein is a method of preparing a subject's cells for topical treatment of a subject in need. Also provided is a topical formulation and methods of treating a subject suffering a skin disorder and pain using the topical formulation.
Aesthetics Biomedical, Inc.

Pharmaceutical formulations for treating skin disorders and methods for fabricating and using thereof

Pharmaceutical compositions for treating, mitigating or preventing inflammatory skin diseases, disorders and/or pathologies are described, the compositions comprising a tetracycline-class antibiotic(s), omega fatty acid(s), and/or nicotinic acid or derivatives thereof. Methods for fabricating the compositions and using them are also described..
Imprimis Pharmaceuticals, Inc.

Corticosteriod containing foam compositions and manufacture thereof

The present invention provides a method of manufacturing foamable, corticosteroid containing compositions as well as methods for treating various skin diseases.. .
Therapeutics Inc.

Halobetasol foam composition and use thereof

The present invention provides a composition and method for treating various skin diseases. The composition is formulated as a foamable composition and includes the corticosteroid halobetasol..
Therapeutics Inc.

Heteroaromatic compounds and their use as dopamine d1 ligands

And pharmaceutically acceptable salts thereof and n-oxides thereof; processes for the preparation of; intermediates used in the preparation of; and compositions containing such compounds (n-oxides thereof or or pharmaceutically acceptable salts of the compound or the n-oxides) and the uses of such compounds (n-oxides thereof or or pharmaceutically acceptable salts of the compound or the n-oxides) for the treatment of d1-mediated (or d1-associated) disorders including cognitive and motivational impairments and negative symptoms associated with illnesses such as schizophrenia, depression, bipolar disorder, parkinson's disease, mild cognitive impairment (mci), alzheimer's disease, lupus, huntington's disease, parkinson's, dyskinesia, adhd, post-traumatic stress disorder, autism spectrum disorder, treatment-resistant depression, major depressive disorder (mdd), drug dependence, tourette's syndrome, tardive dyskinesias as well as impairments associated with age, chronic stress, sleep deprivation, combat, chronic fatigue; endocrine or metabolic diseases such as hyperglycemia, dislipidemia, diabetes, obesity, and sepsis; and cardiovascular disorder such as hypertension. The present invention further provides a d1 agonist with reduced d1r desensitization, a d1 agonist with a reduced β-arrestin recruitment activity relative to dopamine, a d1 agonist interacting significantly with the ser188 but not significantly with the ser202 of a d1r when binding to the d1r, a d1 agonist interacting less strongly the asp103 and interacting less strongly with the ser198 of a d1r when binding to the d1r, and their uses..

Complexes of sirolimus and its derivatives, process for the preparation thereof and pharmaceutical compositions containing them

The invention is directed to a stable complex with controlled particle size, increased apparent solubility and increased dissolution rate comprising as active compound sirolimus or derivatives thereof, which is useful in the prophylaxis of organ rejection in patients receiving renal transplants, in the treatment of psoriasis, facial angiofibromas associated with tuberous sclerosis, fibrofolliculomas found in birt-hogg-dubé syndrome, chronic erosive oral lichen planus, early stage cutaneous t-cell lymphoma, treatment of autoimmune active anterior uveitis, dry eye syndrome, age-related macular degeneration, diabetic macular edema, noninfectious uveitis, telangiectasia, inflammatory skin diseases (dermatitis, including psoriasis and lichen ruber planus), pachyonychia congenita and in the suppression of angiogenesis pathways. More specifically, the complex of the present invention possesses increased apparent solubility, permeability and enhanced biological performance including significantly improved exposure, earlier tmax, higher cmax and higher trough concentrations at 24 hours which will allow the reduction of the dose..
Druggability Technologies Ip Holdco Limited

Topical skin care formulations comprising plant extracts

Disclosed are methods of treating skin with topical skin compositions comprising at least one plant extract.. .
Mary Kay Inc.

Topical skin care formulations comprising plant extracts

Disclosed are methods of treating skin with topical skin compositions comprising at least one plant extract.. .
Mary Kay Inc.

Mass spectrometry imaging of benign melanocytic nevi and malignant melanomas

A method of differentiating benign melanocytic nevi from malignant melanomas is disclosed. The method generally includes subjecting a skin lesion sample from a patient to mass spectrometry to obtain a mass spectrometry protein profile.
Yale University

Information processing apparatus, information processing system, information processing method, and recording medium

There is provided at least one information processing apparatus capable of easily generating a skin color model in which peripheral darkening is considered that is possibly occurring due to an imaging apparatus. At least one embodiment of the information processing apparatus includes an acquisition unit configured to acquire a first image in which a predetermined object is captured with a predetermined exposure condition, and at least one second image in which the predetermined object is captured with an exposure condition or a plurality of exposure conditions different from the predetermined exposure condition; an extraction unit configured to extract color information relating to the predetermined object based on the first image and the at least one second image; and a generation unit configured to generate a color table based on the extracted color information..
Canon Kabushiki Kaisha

System for determining, dispensing, and mixing blended composition for skin treatment

A system and method is provided for providing a cosmetic composition to a user. The system includes an apparatus configured to dispense at least one cosmetic composition into a output container; a user interface configured to receive information about the user; and circuitry configured to receive the information about the user and determine one or more cosmetic compositions to be dispensed into the output container based on the information about the user received at the user interface..
L'oreal

Method and electronic device for skin color detection

The present disclosure discloses a method and a device for skin color detection. The method includes: reading an rgb image, and converting the rgb image from an rgb color space to an r-g color space, and obtaining an image to be detected; traversing and reading each pixel in the image to be detected, and calculating a first probability density of the pixel under a skin gaussian mixture model and a second probability density of the pixel under a non-skin gaussian mixture model according to a pre-established gaussian mixture model; calculating the posteriori probability of the pixel belonging to a skin region according to the first probability density and the second probability density of the pixel; and attributing the pixel to the skin region when determining that the posteriori probability is greater than a preset posteriori probability threshold.
Le Shi Zhi Xin Electronic Technology (tian Jin) Limited

Apparatus for dispensing and mixing blended composition for skin treatment

An apparatus is provided for dispensing a cosmetic composition, including: a cartridge holder configured to hold at least one cartridge that stores a cosmetic composition, the cartridge holder being configured to move the cartridge to a predetermined location; a container receiving area configured to hold a output container beneath the predetermined location; circuitry configured to determine the cosmetic composition in the cartridge holder, control the cartridge holder to move the cartridge holder to the predetermined location based on the determination, and control the cartridge to dispense the cosmetic composition into the output container; and a mixer configured to hold the output container and subject the output container to a predetermined movement to cause contents of the output container to mix together.. .
L'oreal

Biophotonic materials and uses thereof

The present disclosure provides biophotonic materials and methods useful in phototherapy. In particular, the biophotonic materials of the present disclosure include a cohesive matrix, and at least one chromophore, wherein the at least one chromophore can absorb and emit light from within the biophotonic material.
Klox Technologies Inc.

Combination of n-acetyl glucosamine with abscisic acid and uses thereof

Compositions comprising n-acetyl glucosamine and abscisic acid, a pharmaceutically acceptable salt, ester, or isomer thereof, are disclosed. The present invention also relates to the use of such a composition for skin modulation, immune modulation, and tissue growth, such as anti-aging, wound healing, skin graft healing, and stem cell maturation and signaling..

Topical skin compositions having proteins and methods of use

There is provided a topical skin composition directed to one or more desired benefits. The composition includes one or more proteins selected based on the desired skin benefit to be derived by application of the topical skin composition.
Dermaforce Holdings, Llc

Client-server system and terminal

A client-server system includes a server, at least one of a first client and a second client, and server-side computer resources which are attributed to the at least one of a first client and a second client so as to implement a server-side multitasking. The at least one of a first client and a second client distribute the server-side computer resources input-dependently so as to implement a client-side and input-dependent multitasking..

Bioluminescence tomography reconstruction based on multitasking bayesian compressed sensing

Implementations of the present disclosure relate to methods for reconstruction for bioluminescence tomography based on a method of multitask bayesian compressed sensing in the field of medical image processing. The method includes the following operations.

Medical skin examination device

A medical skin examination device configured to diagnose a skin lesion includes: a first storage unit configured to store an original first skin image related to a dermoscopy structure imaged via a dermoscope; an image conversion unit configured to apply high dynamic range (hdr) conversion processing to the first skin image and obtain a second skin image in which the dermoscopy structure is made clear and salient; a second storage unit configured to store the second skin image; and a display control unit configured execute control so as to display at least one of the first skin image and the second skin image.. .

Immune regulatory oligonucleotide (iro) compounds to modulate toll-like receptor based immune response

The invention provides novel immune regulatory oligonucleotides (iro) as antagonist of tlrs and methods of use thereof. These iros have unique sequences that inhibit or suppress tlr-mediated signaling in response to a tlr ligand or tlr agonist.

Cosmetic skin rejuvination

A device for cosmetic treatment of human skin, including: a needle for inserting into the skin; a dc power source electrically connected to the needle for providing negative current to the needle; an anode that is electrically connected to the dc power source to receive positive current, and that is adapted to be placed in contact with the skin of the person into which the needle is inserted to form a closed electrical circuit; at least one rf transmitter coupled to the needle for radiating the area around where the needle is inserted to provide heat while the needle is deployed.. .

Treatment of a skin lesion

The invention provides a spray applicator (1) for topical treatment, the spray applicator (1) comprising a container (2) comprising a treatment liquid (52) under pressure and a propellant (51), wherein the container (2) is in fluid connection with a spray valve system (4) for application of at least part of the treatment liquid (52) on a topical area, wherein the treatment liquid (52) comprises an acid, wherein the container (2) comprises a container wall (20) having a top layer (22) and a top layer coating (21) on said top layer (22), wherein the top layer (22) optionally comprises a metal and wherein the top layer coating (21) comprises a polymer and/or a resin.. .

Probiotic treatment of skin diseases, disorders, and infections: formulations, methods and systems

The present invention teaches compositions, methods and kits for treating skin conditions, including dandruff. In various embodiments, the compositions include an effective amount of one or more probiotic microorganism of vaginal origin and/or a fraction thereof and/or a component of the metabolome for preventing and/or treating skin disorders of the scalp..

Skin color-improving agent and composition for improving skin color

A tocopherol phosphoric acid ester represented by a following formula (1) (in the formula, r1, r2, and r3 each independently represents a hydrogen atom or a methyl group,), a pharmacologically-acceptable salt thereof, or a solvate thereof for use in the improvement of skin color.. .

Chart for evaluating skin color and its application to efficacy evaluation of anti-aging and skin lightening products

The present invention relates to charts, stacks and methods for evaluating skin color of a mammalian subject. The chart may include a substrate and an indicia visible from a first side of the substrate that includes a plurality of images of mammalian skin tones having varying degrees of yellowness, wherein each indicia is correlated with an index value.
Access Business Group International Llc

Methods of treating skin disorders using an anti-il-31ra antibody

The present invention relates to methods of treating patients suffering from contact dermatitis, drug induced delayed type cutaneous allergic reactions, toxic epidermal necrolysis, cutaneous t cell lymphoma, bullous pemphigoid, alopecia aereata, vitiligo, acne rosacea, prurigo nodularis, scleroderma, herpes simplex virus, or combination by administering an il-31ra antagonist.. .
Zymogenetics, Inc.

A skin treatment device for locally treating skin

A skin treatment device (100) for locally treating skin with light is provided that comprises a tip (128), a light emission element (106, 108), a safety mechanism comprising an optical element (124) and an optical element positioning structure (122). The optical element receives a converging light beam from the light emission element.
Koninklijke Philips N.v.

Electromagnetic energy applicator for personal aesthetic skin treatment

An apparatus for safe personal aesthetic skin treatment including a carrier with a plurality of voltage applying electrodes arranged so that at least one electrode operative to contact the skin at any one time, an electrode-to-skin contact detecting mechanism, and a controller communicating with and operative to receive information from the mechanism regarding the status of the electrode-to-skin contact and limit the number of simultaneously activated electrodes such as to enable safe skin treatment and avoid skin ablation.. .
Syneron Medical Ltd

Skin graft product

An apparatus and method for the production of substitute skin that advantageously reduces the amount of donor dermal cells needed from non-wound areas of a patient having a wound to be auto-grafted is reduced by using all of the harvested skin cells. A 3d printer is used to construct a wound graft product from the harvested skin cells without wasting any of the harvested skin cells.
Dermagenesis Llc

Botanical formulations

Disclosed is a topical skin composition, and methods for its use, that includes arctium lappa root extract, epilobium angustifolium extract, and cystoseira amentacea/caespitosa brachycarpa extract.. .
Mary Kay Inc.

Method of treating pre-cancerous lesions with glyphosate, and compositions thereof

A method for treating a pre-cancerous skin lesion on a human subject with glyphosate is described, along with compositions for said treatment.. .

Topical compositions and methods for skin lightening

Embodiments of the invention are generally directed to compositions useful for reducing pigmentation in the skin. The composition may further include other depigmenting agents such as nicotinamide and its melanasome transfer-inhibiting derivatives, 3,3′-thiodipropanoic acid and its tyrosinase-inhibiting derivatives, or resorcinol and its tyrosinase-inhibiting derivatives, in a topically acceptable vehicle..
Avon Products, Inc.

Light-based measurement system and a collagen denaturation measurement and a skin treatment system

The measurement system 110 comprises a light source 120 configured and arranged for emitting a light beam via a polarization modulator 130 to a target position inside the skin 160, wherein the polarization modulator 130 is configured and arranged to simultaneously provide, in use, a first and a second region in a cross-section of the light beam in the target position, the first and the second region being distinct and having a corresponding first and second direction of polarization, the first and the second polarization direction being different from each other, and the measurement system also comprises a detection unit 150 to simultaneously detect a first and a second intensity of reflected light 145, the first intensity corresponding to light reflected from the first region of the light beam in the target position 160, and the second intensity corresponding to light reflected from the second region of the light beam in the target position 160, and the measurement system further comprises a processor being coupled to the detection unit 150 for determining a difference between the first and the second intensity.. .
Koninklijke Philips N.v.

Mobile terminal and controlling method thereof

A mobile terminal and controlling method thereof are disclosed, by which a selection and/or execution of an application can be designated using a list of applications currently executed in a multitasking environment. The present invention includes a display unit, a user input unit configured to receive an input of a command from a user, and a controller, when a plurality of applications are being executed, if there is a first input via the user input unit, controlling a list of a plurality of the currently executed applications to be displayed on a first region, the controller, if one of at least one or more applications running in the background in the list is selected by a second input via the user input unit, controlling the selected application to be displayed on a second region of the display unit by having a prescribed visual effect applied thereto..
Lg Electronics Inc.

Antibodies against human sodium channel nav1.9 and uses thereof for the diagnosis of inflammatory skin diseases

Antibodies against the human sodium channel nav 1.9 are described. Also described, is the use of such antibodies in the diagnosis of inflammatory skin diseases.
Universite D'aix-marseille

Compounds comprising 1,1a,2,5a-tetrahydrospiro[indole-3,2a-pyrrole]-2,5a-dione system as inhibitors p53-mdm2 protein-protein interaction

A spirooxoindole compound represented by the formula selected from the group consisting of formula (ia) and (ib), wherein all symbols are as defined in the description. The compound can find use in a method of prevention and/or treatment of diseases selected from the group consisting of cancer, immune diseases, inflammatory conditions, allergic skin diseases associated with excessive proliferation, and viral infections..
Adamed Sp. Z O.o.

Skin treatment lotion

A system and method for a skin treatment lotion. The lotion has a protecting agent, a moisture absorber, a binding agent, water, and an antibiotic agent or hydrocortisone.

Topical composition for skin treatment to reduce lines and wrinkles of the face and body using a dual dna repair mechanism to address damage caused by aging and ultra-voilet induced damage to the skin with combination of skin turgor enhancement compounds

A topical composition for anti-aging and anti-uv damage treatment of the skin includes water soluble extract of uncaria species, arabidopsis thaliana extract, alpha lipoic acid, dimethylethanolamine, tetrahexyldecyl ascorbate, dimethyl sulfoxide, glycyrrhiza glabra (licorice) root extract, methylsulfonylmethane, phytosterols, d-ribose, tocotrienol, tocopherol, glucosamine hydrochloride, pisum sativum extract; silicates of sodium, magnesium and aluminum, and a dermatologically acceptable liposomal delivery medium. The composition is useful in a method using it for anti-aging skin treatment effecting dna repair in both the nucleus and the mitochondria.

Systems and methods for medical image segmentation and analysis

The present disclosure includes systems, methods, and computer-readable medium for monitoring and analyzing skin lesions. A sequence of images are be received, and color correction, contour detection, and feature detection are performed on the images.
Massachusetts Institute Of Technology

Gesture based human machine interface using marker

The present disclosure relates to system and method for gesture recognition for emulating a mouse for human machine interface wherein displacements, direction of displacements of cursor as also double click actions of mouse can be emulated by instinctive hand gestures. The method uses a marker as gesture interface and therefore does not depend on hand segmentation techniques, which suffer from deficiencies related to lighting conditions, variation of skin color from person to person and complexities of background..
Centre For Development Of Telematics

Increased effectiveness of allylamine drug compounds for topical treatment of fungal infections of the skin and skin appendages

The invention is an increased effectiveness of allylamine drug compounds for topical treatment of fungal infections of skin and skin appendages. The allylamine active ingredient is prepared in an acidic environment; the acidic environment altering the physiochemical properties of the active ingredient resulting in the active ingredient having a positive charge.
Biophile Corporation, Ltd.

Skin cancer treatment

For use in the treatment of skin cancer such as basal cell carcinoma.. .

Lower eyelid treatment

The invention relates to a lower eyelid treatment device (1), which comprises a skin treatment structure (3) having a protruding shape which is able to perform a periodical first movement through a stationary reference point (p) in a skin treatment zone (8) of the device. Said periodical first movement occurs in the reference point (p) at a frequency within a frequency range between 0.5 hz and 3.0 hz.
Koninklijke Philips N.v

Devices and methods for protecting the eye from adjacent skin treatments

A skin care apparatus suitable for use in proximity to a subject's eyes. The apparatus includes a treatment device and a stimulus device.
L'oreal

Ultrasonic scalpel

An ultrasound scalpel that may be used for surgical operations is disclosed in this invention. The ultrasound scalpel comprises an ultrasound generator, housing, transducer horn, retaining member and scalpel blade.

Method and system for implementing generation locks

A system and method for implementing a generation lock for protecting a data structure is provide. The systems and methods synchronizes read and write transactions for a protected data structure in a multitasking environment and provides low latency and improved scalability.
Wind River Systems, Inc.

Topical skin care formulations comprising plant extracts

Disclosed are topical skin compositions and corresponding methods for their use that include plant extracts. One such composition can include a tnf-α inhibitor, wherein said inhibitor is an aqueous extract from the whole plant of polygonum multiflorum, an antioxidant and a tyrosinase inhibitor, wherein said antioxidant and tyrosinase inhibitor is an aqueous extract from the whole plant of lonicera japonica, and a dermatologically acceptable carrier, wherein the composition can include at least 50% by weight of water..
Mary Kay Inc.

Thermosetting biophotonic compositions and uses thereof

The present disclosure provides thermosetting biophotonic compositions and methods useful in phototherapy. In particular, the thermosetting biophotonic compositions of the present disclosure include block copolymer and at least one chromophore solubilized in the block copolymer.
Klox Technologies Inc.

Controlled strain skin treatment devices and methods

Devices, kits and methods described herein may be for wound healing, including but not limited to the treatment, amelioration, or prevention of scars and/or keloids. The packaging, manipulation elements, applicator and/or tensioning device maybe used to apply and/or maintain a strain in an elastic dressing..
Neodyne Biosciences, Inc.

Hand suspension fixture

Described is a hand suspension fixture for recovering from skin grafts on human hands. The hand suspension fixture generally comprises five retention fixtures each adapted to connect to one of five flexible members at a first end.

Managing thread execution in a multitasking computing environment

A thread in a computing system is processed for execution of instructions to perform an action. The action is one of the following: accessing a shared resource or executing a critical section of code.
International Business Machines Corporation

Managing thread execution in a multitasking computing environment

A thread in a computing system is processed for execution of instructions to perform an action. The action is one of the following: accessing a shared resource or executing a critical section of code.
International Business Machines Corporation

Phenyl-substituted nicotinic ligands, and methods of use thereof

Disclosed are compounds and methods of using them to treat a disorder selected from the group consisting of addiction, pain, obesity, schizophrenia, epilepsy, mania and manic depression, anxiety, alzheimer's disease, learning deficit, cognition deficit, attention deficit, memory loss, lewy body dementia, attention deficit hyperactivity disorder (adhd), parkinson's disease, huntington's disease, tourette's syndrome, amyotrophic lateral sclerosis, inflammation, stroke, spinal cord injury, dyskinesias, obsessive compulsive disorder, chemical substance abuse, alcoholism, memory deficit, pseudodementia, ganser's syndrome, migraine pain, bulimia, premenstrual syndrome or late luteal phase syndrome, tobacco abuse, post-traumatic syndrome, social phobia, chronic fatigue syndrome, premature ejaculation, erectile difficulty, anorexia nervosa, autism, mutism, trichotillomania, hypothermia, and disorders of sleep.. .
Duke University

Cancer treatments

This document provides methods and materials related to treating cancer (e.g., skin cancer). For example, methods and materials relating to the use of a composition containing albumin-containing nanoparticle/antibody complexes (e.g., abraxane®/anti-vegf polypeptide antibody complexes) to treat cancer (e.g., skin cancer) are provided..
Mayo Foundation For Medical Education And Research

Biophotonic hydrogels

The present disclosure provides biophotonic hydrogels and methods useful in phototherapy. In particular, the biophotonic hydrogels of the present disclosure include n-hydroxyethyl acrylamide (heaa), and at least one chromophore, wherein the at least one chromophore is not fully photobleached after photopolymerization.
Klox Technologies Inc.

Compositions and methods for treatment of inflammatory skin conditions using allantoin

Embodiments herein provide formulations and methods for treatment of inflammatory skin diseases using allantoin in an amount from about 0.5% to about 15.0% by weight. Inflammatory skin diseases treated by embodiments herein include, without limitation, cutaneous porphyria, sclerodema, epidermolysis bulosa, psoriasis, decubitus ulcers, pressure ulcers, diabetic ulcers, venous stasis ulcers, sickle cell ulcers, ulcers caused by burns, eczema, urticaria, atopic dermatitis, dermatitis herpetiform, contact dermatitis, arthritis, gout, lupus erythematosus, acne, alopecia, carcinomas, psoriasis, rosacea, miliaria, skin infections, post-operative care of incisions, post-operative skin care following any variety of plastic surgery operations, skin care following radiation treatment, care of dry, cracked or aged skin and skin lines as well as other conditions affecting the skin and having an inflammatory component, symptoms thereof, or a combination thereof.
Scioderm, Inc.

Compositions and methods of treatment of inflammatory skin conditions using allantoin

Embodiments herein provide formulations and methods for treatment of inflammatory skin diseases using allantoin in an amount from about 0.5% to about 15.0% by weight. Inflammatory skin diseases treated by embodiments herein include, without limitation, cutaneous porphyria, sclerodema, epidermolysis bulosa, psoriasis, decubitus ulcers, pressure ulcers, diabetic ulcers, venous stasis ulcers, sickle cell ulcers, ulcers caused by burns, eczema, urticaria, atopic dermatitis, dermatitis herpetiform, contact dermatitis, arthritis, gout, lupus erythematosus, acne, alopecia, carcinomas, psoriasis, rosacea, miliaria, skin infections, post-operative care of incisions, post-operative skin care following any variety of plastic surgery operations, skin care following radiation treatment, care of dry, cracked or aged skin and skin lines as well as other conditions affecting the skin and having an inflammatory component, symptoms thereof, or a combination thereof.
Scioderm, Inc.

Topical skin care formulations comprising plant extracts

Disclosed is a topical skin composition and corresponding methods for its use that includes an extract from phaseolus vulgaris, citris sinensis, wedelia trilobata, burretiodendron hsienmu, bauhinia brachycarpa var. Cavaleriei, cystacanthus paniculatus, caesalpinia minax, pueraria wallichii, tetracentron sinense, bridelia insulana, hedyotis verticillata, syzygium fruticosum, cercidiphyllum japonicum, bauhinia glauca, rhododendron siderophyllum, cudrania pubescens, cajanus cajan, wendlandia uvariifolia, siegesbeckia glabrescens, azolla imbricate, juncus bufonius, poikilospermum suaveolens, clerodendrum trichotomum var.
Mary Kay Inc.

Modulating gamma-c-cytokine activity

Embodiments relate to peptide antagonists of γc-family cytokines, which is associated with important human diseases, such as leukemia, autoimmune diseases, collagen diseases, diabetes mellitus, skin diseases, degenerative neuronal diseases and graft-versus-host disease (gvhd). Thus, inhibitors of γc-cytokine activity are valuable therapeutic and cosmetic agents as well as research tools.
Bioniz, Llc

Urea compounds and their use as enzyme inhibitors

Or a pharmaceutically acceptable salt or derivative thereof. The compound may be used in the treatment or prevention of a disorder selected from appetite regulation, obesity, metabolic disorders, cachexia, anorexia, pain, inflammation, neurotoxicity, neurotrauma, stroke, multiple sclerosis, spinal cord injury, parkinson's disease, levodopa-induced dyskinesia, huntington's disease, gilles de la tourette's syndrome, tardive dyskinesia, dystonia, amyotrophic lateral sclerosis, alzheimer's disease, epilepsy, schizophrenia, anxiety, depression, insomnia, nausea, emesis, alcohol disorders, drug addictions such as opiates, nicotine, cocaine, alcohol and psychostimulants, hypertension, circulatory shock, myocardial reperfusion injury, atherosclerosis, asthma, glaucoma, retinopathy, cancer, inflammatory bowel disease, acute and chronic liver disease such as hepatitis and liver cirrhosis, arthritis and osteoporosis..

Use of free radical scavengers for protecting and treating skin and hair damages caused by chemotherapy

The invention also concerns a method for the protection or treatment of skin and hair damages of a mammal caused by chemotherapy. The invention further relates to a kit for the protection or treatment of hair damages caused by chemotherapeutic treatment consisting of a topical composition comprising microparticles together with free radical scavengers and a shampoo for an effective hair cleaning and supporting the hair treatment.

Composition for external use skin preparation, containing thioredoxin

Provided is a composition for an external use skin preparation, containing thioredoxin, and more specifically, to a composition which contains thioredoxin thereby providing an overall improvement in skin condition such as a remarkable improvement in skin moisturization, reduction in a transepidermal water loss, sebum control, pore contraction, an improvement in skin color through blood circulation improvement, and the like.. .
Amorepacific Corporation

Cosmetic skin-lightening composition

A method includes using such compositions.. .

Skin treatment composition

A composition for application to mammalian skin. The composition can include an emulsion comprising an oil phase.
3m Innovative Properties Company

Integrated tablet computer in hot and cold dispensing machine

Improvements a hot and cold dispensing machine is disclosed. The machine integrates a tablet computer with hot and cold dispensing machines, including coffee machines that transform the dispensing machine into a fully interactive machine that enables an unlimited number of features to be added as functionalities.

Novel tricyclic modulators of cannabinoid receptors

The compounds of the invention are modulators of cannabinoid receptors cb1 or cb2. The compounds can be used for the prevention or treatment of, e.g., pain, cancer, skin diseases, weight-associated disorders, chemical addictions, psychiatric disorders, neurodegenerative disorders, bone diseases, and inflammatory diseases.
The University Of Montana

Needle system

A needle system for penetrating to or passing thought an object or an organ comprising a semiconductor die, one or more needles, wherein the needles move relative to the die using one or more actuators. The actuators are controlled by a controller wherein the controller instruct the needle to penetrate into or to pass through and/or retract from the object or organ.

Integrated double cannula for ecmo

The present invention relates to an integrated double cannula for ecmo. The integrated double cannula is configured to be inserted into a blood vessel through skin for ecmo.
Samsung Life Public Welfare Foundation

Pharmaceutical compositions comprising 7-(1h-imidazol-4-ylmethyl)-5,6,7,8-tetrahydro-quinoline for treating skin diseases and conditions

The present invention relates to a method for treating skin diseases and skin conditions in a patient in need thereof which comprises of administering a therapeutically effective amount of a pharmaceutical composition comprising a therapeutically effective amount of 7-(1h-imidazol-4-ylmethyl)-5,6,7,8-tetrahydro-quinoline, or its individual enantiomers or the tautomers thereof, or a pharmaceutically acceptable salt thereof.. .
Allergan,inc.

Polyvinylacetal resin for heat-developable photosensitive material and heat-developable photosensitive material

An object of the present invention is to provide: a polyvinyl acetal resin for a heat-developable photosensitive material capable of preventing skinning in the coating process of the photosensitive layer of the heat-developable photosensitive material, preventing deterioration of image characteristics and coloration of the coating solution, and suppressing the occurrence of odor at the time of producing the heat-developable photosensitive material and heat development. The present invention provides a polyvinyl acetal resin for a heat-developable photosensitive material used for a photosensitive layer of the heat-developable photosensitive material, which has a residual acetyl group content of 25 mol % or less, residual hydroxyl group content of 17-35 mol %, polymerization degree of 200 to 3,000, which is obtained by an acetalization of a polyvinyl alcohol mixture containing polyvinyl alcohol resins having different polymerization degrees, the content of the polyvinyl alcohol having a polymerization degree of 600 or less being 50 wt % or higher in the polyvinyl alcohol mixture..
Sekisui Chemical Co., Ltd.

Skinning of ceramic honeycomb bodies

An in situ inspection system and method to inspect a honeycomb body (122) skin in a skinning system. The inspection system includes a line illuminator (148) to generate a line illumination on the skin (136) perpendicular to an axial direction (112) of the honeycomb body travel, and a detector (152) to detect the line illumination scattered from the skin (136) and generate a signal based on the detected line illumination.
Corning Incorporated

Light-activated acne treatment

A skin treatment device uses blue-light therapy to treat acne or other skin conditions. The device includes a positioning mechanism that allows a user to position the device on a target treatment area.

Skin resurfacing device, controlling apparatus and controlling skin resurfacing device

The present invention provides a controlling apparatus for a skin resurfacing device performing a surgical procedure on a human skin with a surgical needle, including: a controller 20; a voltage regulator 50 configured to regulate a voltage supplied to the skin resurfacing device from a power supply 10 according to a control of the controller; and a starting switch 80 configured to turn on/off a supply of power between the voltage regulator and the skin resurfacing device, in which the controller controls the voltage regulator so as to output a preset jump start voltage to the skin resurfacing device every time the starting switch is turned on, if a jump start function that is a function of starting the skin resurfacing device is set by a starting voltage when an operating voltage of the skin resurfacing device is lower than the starting voltage of the skin resurfacing device at the time of the surgical procedure.. .

Composition, treating skin

A composition for wound healing and/or skin treatment comprises honey and a carbonate and/or bicarbonate salt. The salt is preferably capable of releasing co2.
Biomedical Concepts Llc

Treatment of inflammatory and infectious skin disorders

Disclosed herein is a composition comprising of resveratrol and/or derivatives thereof and/or functionally related compounds and benzoyl peroxide and/or derivatives thereof and/or functionally related compounds for the treatment of acne and other inflammatory or infectious skin disorders. Also disclosed are methods of treating acne and other inflammatory and infectious skin disorders using the compositions described herein..
The Regents Of The University Of California

Cosmetic compositions for bleaching the skin

The invention relates to a cosmetic composition for bleaching the skin, which includes a) at least one oily plant extract from the glycyrrhiza genus and b) at least one ascorbic acid ester. The invention further relates to the cosmetic, nontherapeutic use of the cosmetic composition according to the invention to treat excessive pigmentation, pigmentation disorders, age spots, and/or post-inflammatory hyperpigmentation of the skin, and to a method for producing a cosmetic skin-bleaching composition in the form of an o/w or a w/o emulsion, wherein an oily extract from licorice roots is dissolved in the water phase by the addition of an ascorbic acid ester..
Henkel Ag & Co. Kgaa

Dynamic data masking system and method

A system and method for providing dynamic data masking for databases through a data masking apparatus.. .
Hexatier Ltd

Novel compounds as diacylglycerol acyltransferase inhibitors

This invention relates to novel compounds which are inhibitors of acyl coenzyme a: diacylglycerol acyltransferase 1 (dgat-1), to pharmaceutical compositions containing them, to processes for their preparation, and to their use in therapy, alone or in combination with weight management therapies or other triglyceride lowering therapy for the prevention or treatment of diseases related to dgat-1 dysfunction or where modulation of dgat-1 activity may have therapeutic benefit including but not limited to obesity, obesity related disorders, genetic (type 1, type 5 hyperlipidemia) and acquired forms of hypertriglyceridemia or hyperlipoproteinemia-related disorders, caused by but not limited to lipodystrophy, hypothyroidism, medications (beta blockers, thiazides, estrogen, glucocorticoids, transplant) and other factors (pregnancy, alcohol intake), hyperlipoproteinemia, chylomicronemia, dyslipidemia, non-alcoholic steatohepatitis, diabetes, insulin resistance, metabolic syndrome, cardiovascular outcomes, angina, excess hair growth (including syndromes associated with hirsutism), nephrotic syndrome, fibrosis such as myocardial, renal and liver fibrosis, hepatitis c virus infection and acne or other skin disorders.. .
Glaxosmithkline Llc

Treatment of inflammatory skin disorders

The invention relates to methods of using an effective amount of activated protein c (apc) to treat an individual for a skin disorder characterised by the presence of hyperproliferative keratinocytes.. .
Zz Biotech Llc

Method and system for assessing motion symptoms

A state of progression in an individual of a disease or treatment having motion symptoms is determined. A time series of accelerometer data is obtained from an accelerometer worn on an extremity of the person, over an extended period during everyday activities of the person.
Global Kinetics Corporation Pty Ltd

Electronic device using information on skin color type and control method thereof

An electronic device and method that detects an event related to the user's skin and performs a function corresponding to the event by using information on the skin color type of the user, and further provides a control method thereof. The occurrence of an event is detected that is related to at least a part of a user's body.
Samsung Electronics Co., Ltd.

Heteroaryl substituted pyrrolo[2,3-b] pyridines and pyrrolo[2,3-b] pyrimidines as janus kinase inhibitors

The present invention provides heteroaryl substituted pyrrolo[2,3-b]pyridines and heteroaryl substituted pyrrolo[2,3-b]pyrimidines that modulate the activity of janus kinases and are useful in the treatment of diseases related to activity of janus kinases including, for example, immune-related diseases, skin disorders, myeloid proliferative disorders, cancer, and other diseases.. .
Incyte Holdings Corporation

Treatment of hyperkinetic movement disorders

Methods for treating hyperkinetic diseases and disorders, such as tardive dyskinesia, are provided. In a certain embodiment, the potent vmat2 inhibitor (+)α-3-isobutyl-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2h-pyrido[2,1-a]isoquinolin-2-ol ((+)α-htbz) is used in the methods described herein for treating a subject in need thereof..
Neurocrine Biosciences, Inc.

Pyridine and pyrazine derivative for the treatment of cf

The present invention provides pyridine and pyrazine derivatives which restore or enhance the function of mutant and/or wild type cftr to treat cystic fibrosis, primary ciliary dyskinesia, chronic bronchitis, chronic obstructive pulmonary disease, asthma, respiratory tract infections, lung carcinoma, xerostomia and keratoconjunctivitis sire, or constipation (ibs, ibd, opioid induced). Pharmaceutical compositions comprising such derivatives are also encompassed..
Novartis Ag

Matrix-metalloproteinase (mmp) inhibitory extract and methods of use thereof

A cosmetic skin care product comprising a therapeutically effective amount of a honey extract is described, the honey extract having a phenolic compound to saccharides ratio of at least 5 times greater than the raw honey from which the extract is derived and including a mixture of at least ethanol, water and one or more mmp inhibitory phenolic compounds.. .
Comvita Limited

N-(pyrid-4-yl)amides and n-(pyrimidin-4-yl)amides and their pharmaceutical and cosmetic use

The present invention relates generally to the field of pharmaceuticals and cosmetics. More specifically, the present invention pertains to certain n-(pyrid-4-yl)amides and n-(pyrimidin-4-yl)amides of the following formula which are potent modulators (e.g., inhibitors) of an androgen receptor, and which are useful, for example, in therapy, for example, in the treatment of a dermatological disease or disorder; a disease or disorder of the sebaceous gland(s); acne; hyperseborrhoea; oily skin; seborrhoeic dermatitis; hyperpilosity or hirsutism; atopic dermatitis; or androgenic alopecia; especially acne.
Galderma Research & Development

Skin treatment device

A skin treatment device includes: a shell body; a pressing bar, formed with a first end mounted in the shell body and a second end protruded from one distal end of the shell body and formed with a squeezing part having a through hole; a bactericidal lamp, installed in the shell body and including a bactericidal light source capable of generating plural bactericidal light beams passing the through hole; and a cover member, disposed at one distal end of the shell body, served to cover the second end and including a light condensing lens disposed corresponding to the through hole and the bactericidal lamp. Accordingly, when the bacteria existed on the skin or in skin pores are exposed to the bactericidal light beams, the bacteria can be naturally deceased..
Kinpo Electronics, Inc.

Devices and methods for treating the skin

According to some embodiments, a skin treatment assembly comprises a handpiece comprising a distal end, the handpiece comprising a recess or cavity configured to receive a cartridge or other fluid container, a tip configured to be positioned along the distal end of the handpiece, the tip being configured to contact a skin surface of a subject during use, and at least one rollerball configured to extend to or near the tip, wherein the rollerball is configured to be in fluid communication with an interior of a cartridge or other fluid container secured to the handpiece, wherein the at least one rollerball is configured to contact the skin surface of the subject during use and to facilitate the delivery of fluids to said skin surface as the rollerball is moved relative to said skin surface.. .
Edge Systems Llc

Use of coumarin derivatives for the preparation of drugs for treating skin diseases

Wherein n equals 0 or 1, z represents o or s, r1 represents one group chosen among the group consisting of hydrogen, c1-c7 alkyl, substituted, or not, by a halogen, a hydroxyl or a —o—r12 group, wherein r12 is a c1-c7 alkyl, a group —ch2—o—co—r5 wherein r5 is chosen among a hydrogen atom and a c1-c7 alkyl, substituted or not by at least one halogen, a group —o—r13, wherein r13 is chosen among hydrogen and a c1-c7 alkyl, an amine or a —ch2-amine, r′1 represents a group chosen among hydrogen and —o—r14, wherein r14 is chosen among hydrogen and a c1-c7 alkyl, and r2 is chosen among the group consisting of a c1-c7 alkyl, a c3-c6 cycloalkyl, an aryl group, and an heteroaryl group for the treatment of pathologies involving excess activity of at least one member of the kallikrein family.. .

Use of 2,5-dihydroxybenzene compounds and derivatives for the treatment of skin cancer

The present invention relates to the use of a 2,5-dihydroxybenzene derivative of formula (i) or a pharmaceutically acceptable salt, solvate, isomer, or prodrug thereof for the treatment and/or prophylaxis of, inter alia, skin cancer.. .
Amderma Pharmaceuticals, Llc

Heteroaromatic compounds and their use as dopamine d1 ligands

And pharmaceutically acceptable salts thereof; processes for the preparation of; intermediates used in the preparation of; and compositions containing such compounds or salts, and their uses for treating d1-mediated (or d1-associated) disorders including, e.g., schizophrenia (e.g., its cognitive and negative symptoms), cognitive impairment (e.g., cognitive impairment associated with schizophrenia, ad, pd, or pharmacotherapy therapy), adhd, impulsivity, compulsive gambling, overeating, autism spectrum disorder, mcl, age-related cognitive decline, dementia, rls, parkinson's disease, huntington's chorea, anxiety, depression, mdd, trd, bipolar disorder, chronic apathy, anhedonia, chronic fatigue, post-traumatic stress disorder, seasonal affective disorder, social anxiety disorder, post-partum depression, serotonin syndrome, substance abuse and drug dependence, drug abuse relapse, tourette's syndrome, tardive dyskinesia, drowsiness, excessive daytime sleepiness, cachexia, inattention, sexual dysfunction, migraine, sle, hyperglycemia, atherosclerosis, dislipidemia, obesity, diabetes, sepsis, post-ischemic tubular necrosis, renal failure, hyponatremia, resistant edema, narcolepsy, hypertension, congestive heart failure, postoperative ocular hypotonia, sleep disorders, and pain.. .

Skin care system, device and method

The present invention relates to a skin care system (10), comprising: (i) a skin treatment device (12) for treating a skin of a user; (ii) a receiving unit (14) for receiving information on the skin of the user; and (iii) an evaluation unit (16) which is configured to evaluate the received information on the skin of the user and to determine based on said evaluation one or more personalized device settings for operating the skin treatment device (12). The skin treatment device (12) comprises a control unit (36) which is configured to operate the skin treatment device (12) upon initiation based on the determined one or more personalized device settings..
Koninklijke Philips N.v.

Fluid skin treatment systems and methods

The present invention relates to devices for dermatology and more particularly to fluid enhanced skin treatment system for skin rejuvenation that can optionally use an abrasive probe for removing epidermal layers while contemporaneously providing for the infusion of therapeutic fluids into the skin.. .

Use of a composition comprising arabic gum (ag) for improving gut impermeability

The use of a nutritional composition including arabic gum (ag) improves gut impermeability. The nutritional composition also improves conditions like abdominal pain, chronic or not, insomnia, bloating, flatulence, shortness of breath, gluten intolerance, malnutrition, muscle cramps, multiple chemical sensitivities, muscle pain, myofascial pain, mood swings, poor exercise tolerance, poor immunity, poor memory, recurrent skin rashes, brittle nails, hair loss, food allergies, constipation, diarrhea, liver dysfunction, brain fatigue, abdominal spasms, constant hunger pains, depleted appetite, irritable bowel syndrome, chemotherapy, food allergies, acne, liver dysfunction or inflammation of the bowel..
Nexira International

Luminate face mask

The present invention features novel cosmetic skin care compositions for improving the appearance of skin, particularly the reducing the appearance of age spots and discoloration.. .
Jan Marini Skin Research

Cartridges for the deposition of treatment compositions on keratinous surfaces

A micro electromechanical ink jet printing system that has a cartridge having a body that defines a core, and a die that contains one or more nozzles. There is a treatment composition contained within the cartridge core.
The Procter & Gamble Company

Methods for preparing a skin graft without culturing or use of biologics

The present invention generally relates to methods for preparing a skin graft without culturing or use of biologics. .
Kci Licensing, Inc.

Drive method and drive device of liquid crystal display

The present invention provides a drive method and a drive device of a liquid crystal display, and the drive method comprises: receiving an image to display; implementing skin color detection to the image pixels of the image to display to determine nude pixel and non skin color pixel; setting different skin color weights for the nude pixel and the non skin color pixel; implementing the color washout compensation to the image to display according to the skin color weight; driving the liquid crystal panel to show the image to display after the color washout compensation. With the aforesaid arrangement, the present invention preferably improves the resolution and viewing angle of the display at the same time..
Shenzhen China Star Optoelectronics Technology Co., Ltd.

Enforced unitasking in multitasking systems

A computer system includes one or more devices that are capable of multitasking (performing at least two tasks in parallel or substantially in parallel). In response to detecting that one of the devices is performing a first one of the tasks, the system prevents the devices from performing at least one of the tasks other than the first task (such as all of the tasks other than the first task).
Yagi Corp.

Polymeric substrates with immobilized antibodies and production thereof

The present invention relates to biofunctional polymeric substrates product comprising immobilized antibodies that selective bind to antigens namely autologous growth factors and an inflammatory molecule, uses and method of production. The bio-functional polymeric substrate can be used in a quantification method of antigens namely soluble growth factors, inflammatory molecules and hormones or the biofunctional polymeric substrate can be used to isolate extracellular vesicules.
Association For The Advancement Of Tissue Engineering And Cell Based Technology And Therapie





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