This page is updated frequently with new Sensitizer-related patent applications.
|Alkyne-, azide- and triazole-containing flavonoids as modulators for multidrug resistance in cancers|
A triazole bridged flavonoid dimer compound library was efficiently constructed via the cycloaddition reaction of a series of flavonoid-containing azides (az 1-15) and alkynes (ac 1-17). These triazole bridged flavonoid dimers and their precursor alkyne- and azide-containing flavonoids were screened for their ability to modulate multidrug resistance (mdr) in p-gp-overexpressed cell line (lcc6mdr), mrp1-overexpressed cell line (2008/mrp1) and bcrp-overexpressed cell line (hek293/r2 and mcf7-mx100).
|Fluorinated photoresist with integrated sensitizer|
A method of patterning a device comprises providing on a device substrate a layer of a fluorinated photopolymer comprising at least three distinct repeating units including a first repeating unit having a fluorine-containing group, a second repeating unit having an acid- or alcohol-forming precursor group, and a third repeating unit having a sensitizing dye. The photopolymer has a total fluorine content in a range of 15 to 60% by weight.
|Metal particle enhanced forster resonance energy transfer for organic optoelectronic device|
A photovoltaic device that includes an organic or quantum dot sensitizer layer for absorbing light spectra and providing excitons. The sensitizer layer may include metal particles embedded therein for increased exciton transfer efficiency.
International Business Machines Corporation
|Peptides whose uptake by cells is controllable|
A generic structure for the peptides of the present invention includes a-x-b-c, where c is a cargo moiety, the b portion includes basic amino acids, x is a cleavable linker sequence, and the a portion includes acidic amino acids. The intact structure is not significantly taken up by cells; however, upon extracellular cleavage of x, the b-c portion is taken up, delivering the cargo to targeted cells.
The Regents Of The University Of California
|Flow-through pathogen reduction|
Embodiments are described for reducing pathogens in a fluid. The embodiments may include systems, apparatuses, and methods.
Terumo Bct Biotechnologies, Llc
|Systems and methods for treatments of an eye with a photosensitizer|
A formulation for an eye treatment includes a photosensitizer and a permeability enhancing composition. The permeability enhancing composition includes one or more permeability enhancers.
|Dual-sensitizer-containing luminescent compounds, conjugates, and uses thereof|
The invention relates to novel luminescent compositions of matter containing two fluorophores (sensitizers), synthetic methods for making the compositions, macromolecular conjugates of the compositions, and the use of the compositions and their conjugates in various methods of detection. The invention also provides kits containing the compositions and their conjugates for use in the methods of detection..
Rutgers, The State University Of New Jersey
|Photopolymerizable liquid composition|
The subject matter of the present invention is a photopolymerizable liquid composition comprising at least one epoxidized polybutadiene prepolymer, at least one cationic photoinitiator, and at least one thioxanthone-derived photosensitizer, which can, for example, be in the form of a liquid dressing. The subject matter of the invention is also a process for obtaining a polymerized film from said photopolymerizable liquid composition, characterized in that said composition is applied to tissues such as the skin, the skin appendages or the mucous membranes so as to form a uniform liquid film, and the film thus obtained is subjected to ultraviolet radiation, preferably ultraviolet-visible radiation having a wavelength of between 380 and 405 nm, preferably between 385 and 395 nm..
Centre National De La Recherche Scientifique
|Sonosensitizer composition containing titanium oxide nanoparticle as active ingredient, composition for preventing or treating cancer comprising the same, and the preparation thereof|
The present invention relates to a sonosensitizer composition containing titanium dioxide nanoparticles as an active ingredient, a composition for preventing or treating cancer containing the same, and a method of preparing the same. The sonosensitizer of the present invention can solve the problem of the conventional photosensitizer, which can be used only when light can reach the target area, and increase the accumulation level of the sonosensitizer of the present invention to a maximum level within a short time, thereby enabling reduction of the time required for treatment and, due to its human-friendly stability, effective use in cancer treatment..
Research & Business Foundation Sungkyunkwan University
|Method of altering the refractive properties of an eye|
The present invention relates to a method of altering the refractive properties of the eye, the method including forming a pocket in a cornea of an eye of a patient so as to gain access to tissue bounding the pocket; after the pocket in the cornea has been formed, applying a photosensitizer inside the pocket so that the photo sensitizer permeates at least a portion of the tissue bounding the pocket, the photosensitizer facilitating cross-linking of the tissue bounding the pocket; inserting a lens implant into the pocket so as to change the refractive properties of the eye; and irradiating the cornea so as to activate cross-linkers in the portion of the tissue bounding the pocket and thereby stiffen the cornea and prevent corneal ectasia of the cornea.. .
Silicon phthalocyanine complex, preparation method and medicinal application thereof
The present invention relates to a silicon phthalocyanine complex, the preparation method and the medicinal application thereof. The present invention particularly relates to a silicon phthalocyanine complex of formula (i), the preparation method thereof and a pharmaceutical composition comprising the same, as well as the use thereof as a photosensitizer, in particular the use in the treatment of cancers, wherein each substituent in formula (i) is the same as defined in the description..
Shenzhen China Resources Gosun Pharmaceutical Co., Ltd.
Photosensitization chemical-amplification type resist material, forming pattern using same, semiconductor device, mask for lithography, and template for nanoimprinting
A photosensitization chemical-amplification type resist material according to the present invention is used for a two-stage exposure lithography process, and contains (1) a developable base component and (2) a component generating a photosensitizer and an acid through exposure. Among three components consisting of (a) an acid-photosensitizer generator, (b) a photosensitizer precursor, and (c) a photoacid generator, the above component contains only the component (a), any two components, or all of the components (a) to (c)..
(bacterio)chlorophyll photosensitizers for treatment of eye diseases and disorders
An ophthalmic composition is provided, comprising chlorophyll or bacteriochlorophyll compounds for photodynamic treatment (pdt) of diseases, disorders and conditions associated with corneal or scleral anomalies, such as corneal thinning and scleral stretching.. .
Yeda Research And Development Co. Ltd.
Phosphorescent organic light emitting diodes using singlet fission material
An organic light emitting device (oled) is provided. The oled includes, an anode; a cathode; and an emissive layer disposed between the anode and the cathode.
The Regents Of The University Of Michigan
Nanoscale carriers for the delivery or co-delivery of chemotherapeutics, nucleic acids and photosensitizers
Nanoscale coordination polymer nanoparticles for the co-delivery of multiple therapeutic agents are described. The multiple therapeutic agents can include a combination of different chemotherapeutic agents, a combination of one or more chemotherapeutic agents and one or more nucleic acids, such as small interfering rna (sirna) or microrna, a combination of one or more chemotherapeutic agents and a photosensitizer (i.e., for use in photodynamic therapy), or a plurality of different sirnas.
The University Of North Carolina At Chapel Hill
Oxadiazole based photosensitizers for use in dye-sensitive solar cells and photodynamic therapy
An oxadiazole dye for use as an organic photosensitizer. The oxadiazole dye comprising donor-π-spacer-acceptor type portions in which at least one of an oxadiazole isomer acts as a π-conjugated bridge (spacer), a biphenyl unit acts as an electron-donating unit, a carboxyl group act as an electron acceptor group, and a cyano group acts as an anchor group.
King Fahd University Of Petroleum And Minerals
Organic dyes incorporating the oxadiazole moiety for efficient dye-sensitized solar cells
An oxadiazole dye for use as an organic photosensitizer. The oxadiazole dye comprising donor-π-spacer-acceptor type molecules in which at least one of an oxadiazole group acts as a π-conjugated bridge (spacer), a naphthyl unit acts as an electron-donating unit, a carboxyl group act as an electron acceptor group, and a cyano group acts as an anchor group.
King Fahd University Of Petroleum And Minerals
Photovoltaic device comprising porous titanium oxide layer, first hole transport layer, and second hole transport layer
A photovoltaic device according to an aspect of the present disclosure includes a first electrode, a second electrode positioned to face the first electrode, a porous titanium oxide layer on a surface of the first electrode facing the second electrode, a first hole transport layer between the porous titanium oxide layer and the second electrode, and a second hole transport layer between the first hole transport layer and the second electrode. The porous titanium oxide layer contains a porous titanium oxide that supports a photosensitizer.
Direct oxidation of methane to formaldehyde and methanol
A process for the direct oxidation of methane to c1-oxygenates (formaldehyde and methanol) has been developed. The process involves a gas stream, comprising methane, an oxidizing agent (such as air, or oxygen blended with an inert diluent), and a nitrogen oxide as a gas phase sensitizer at oxidation conditions to produce c1-oxygenates, such as formaldehyde and methanol.
Continuous preparation high-purity quadricyclane
The invention discloses a continuous process for producing high-pure quadricyclane, in which “a reaction-rectification integral process” or “a reaction followed by rectification process” may be employed. The two processes both use a novel composite catalyst which is obtained by loading an organic photo-sensitizer on a solid photocatalyst, and the composite catalyst has a high activity and a good stability.
Composite catalyst for the photocatalytic isomerisation of norbornadiene to prepare quadricyclane and process for making the catalyst
The present invention discloses a composite catalyst for the photocatalytic isomerisation of norbornadiene to prepare quadricyclane, comprising: a solid photocatalyst, selected from the group consisting of tio2, ti-mcm-41, ti-sba-15, zno, wo3, ta2o5 or srtio3; and an organic photo-sensitizer loaded on the surface or in the channel of said solid photocatalyst, selected from benzophenone, acetophenone, michler's ketone, tetraethyl michler's ketone, and diethyl michler's ketone, where the organic photo-sensitizer is present in the solid photocatalyst in an amount of 0.5% to 20% by weight. The catalyst of the invention can catalyze a target reaction under the condition that no solvent is used, and the yield of the target product quadricyclane is higher.
Pre-concertation apparatus & method
The present invention relates to concentrating disease causing agents, such as foodborne pathogens, from complex media to expedite their detection. In particular, the present invention relates to a method to pre-concentrate pathogens rapidly, thereby enabling earlier detection times.
Photosensitive dry film compositions
A photosensitive dry film composition includes a hexaarylbiimidazole blend, a photosensitizer that absorbs in the 350 to 410 nm wavelength range and a hydrogen donor. The hexaarylbiimidazole blend includes a hexaarylbiimidazole having a molar extinction coefficient of at least 4,000 in the 350 to 410 nm wavelength range and a hexaarylbiimidazole having a molar extinction coefficient of less than 4,000 in the 350 to 410 nm wavelength range..
E I Du Pont De Nemours And Company
Use of photosensitive molecules and metal complexes as oxygen scavenger elements
An oxygen-scavenging composition for food packaging applications comprising (i) a polymeric resin, (ii) one or more oligomeric photosensitizers, (ill) a metal salt, (iv) a sacrificial oxidizable substrate and optionally (v) additional components is provided.. .
Systems and methods for photoactivating a photosensitizer applied to an eye
An antimicrobial treatment system comprises a wearable photoactivation device. The wearable photoactivation device includes a body configured to be positioned on a head of a subject over one or more eyes of the subject.
Combination of pharmaceutical preparations for tumor chemotherapy
The present invention provides a combination of pharmaceutical preparations for tumor chemotherapy, comprising a cell vesicles preparation with cell vesicles derived from apoptotic tumor cells for sensitizing tumor cells, and a chemotherapy drugs preparation for treating tumors. The combination of pharmaceutical preparations for tumor chemotherapy provided by the present invention uses cell vesicles derived from apoptotic tumor cells as sensitizers of tumor cells, in combination with the chemotherapy drugs preparation for treating tumors, may allow more chemotherapy drugs to enter tumor cells, so as to achieve reversal of drug resistance characteristic of tumor cells, and enhance killing effects of chemotherapy drugs against tumor cells..
Hubei Soundny Biotechnology Co., Ltd.
Method of imaging living tissue
A method of imaging living tissue is provided. The method includes introducing a photoacoustic contrast agent comprising or consisting of a photosensitizer into living tissue; and obtaining an image of the living tissue by photoacoustic imaging.
Agency For Science, Technology And Research
Porphyrin based sensitizer for dye-sensitized solar cell
The present invention relates to compounds of formula (i) based on a porphyrin core and a π-conjugated linker or acceptor introduced between the porphyrin core and an anchoring group having a high absorption coefficient covering the whole uv-visible and near-infrared spectral response, and their use as sensitizer or dye and an electrochemical or optoelectronic device including a compound of the invention.. .
Ecole Polytechnique Federale De Lausanne (epfl)
Soluble graphene nanostructures and assemblies therefrom
Disclosed herein is a method for preparing large soluble graphenes. The method comprises attaching one or more hindering groups to the graphene, which can prevent face-to-face graphene stacking by reducing the effects of inter-graphene attraction.
Indiana University Research And Technology Corporation
Liquid photoreactive composition and fabricating structures
A method of fabricating a structure includes disposing a liquid photoreactive composition on a substrate, exposing a portion of the liquid photoreactive composition to laser light of sufficient intensity and wavelength to cause polymerization via two-photon excitation of the two-photon sensitizer and polymerization of a portion of the liquid photoreactive composition thereby providing an exposed composition; and developing the exposed composition to provide the structure. The liquid composition includes: at least one cationically polymerizable polyepoxide; at least one compound comprising free-radically polymerizable groups; an effective amount of a two-photon photoinitiator system, wherein the weight ratio of component (a) to component (b) is from 25:75 to 75:25, inclusive.
3m Innovative Properties Company
Liquid crystal display device, radiation-sensitive resin composition, interlayer insulating film, producing interlayer insulating film, and manufacturing liquid crystal display device
A liquid crystal display device 1 includes an array substrate 15 and a color filter substrate 90 paired with and disposed facing each other, a liquid crystal layer 10 formed from a polymerizable liquid crystal composition and disposed between the array substrate 15 and the color filter substrate 90, and an interlayer insulating film 52 laminated on a side of the array substrate 15 closer to the liquid crystal layer 10. The interlayer insulating film 52 is produced from a radiation-sensitive resin composition that contains [a] a polymer and [b] a photosensitizer, and has a transmittance of 70% or higher for light having a wavelength of 310 nm at a film thickness of 2 μm..
Methods, apparatuses, and compositions to prevent infections
Embodiments of the present technology may include a composition for reducing microorganisms in the anterior nares or at other body sites. The composition may include a photosensitizer and a substance that enhances the eliminating, destroying, killing, or inhibiting of microorganisms in the anterior nares..
Lighting systems and methods of using lighting systems for in virto potency assay for photofrin
Presently disclosed is a lighting system and methods of using the lighting system for in vitro potency assay for photofrin. The lighting system includes a lamp housing, a first lens, an infrared absorbing filter, an optical filter, and a second lens.
Concordia Laboratories Inc.
Adhesive composition for polarizing plate
An adhesive composition for a polarizing plate of the present invention comprises, on the basis of 100 parts by weight of a polymerizable component: the polymerizable component comprising (a) approximately 50-90 parts by weight of an epoxy group-containing compound and (b) approximately 10-50 parts by weight of a (meth)acrylate monomer; (c) approximately 1-7 parts by weight of a photoacid generator; and (d) approximately 0.1-7 parts by weight of at least one between a photosensitizer and a photopolymerization initiator, wherein the epoxy group-containing compound (a) comprises: (a1) approximately 50-95 parts by weight of an alicyclic epoxy group-containing compound; and (a2) 1 to approximately 50 parts by weight of an aromatic group-containing epoxy group-containing compound, on the basis of 100 parts by weight of the epoxy group-containing compound (a), and the mass ratio of the alicyclic epoxy group-containing compound (a1) to the aromatic group-containing epoxy group-containing compound (a2) can be approximately 3:1 to approximately 95:1. Accordingly, embodiments of the present invention can provide: an adhesive composition for a polarizing plate, having all the properties of sufficient initial curing, adhesion and reliance; and a polarizing plate and an optical display device comprising the same..
Samsung Sdi Co., Ltd.
Radioluminescent compound for radiotherapy and deep photodynamic therapy and device for deep photodynamic therapy
A radioluminescent compound for radiotherapy and deep photodynamic therapy (deep pdt), the radioluminescent compound including a molecular conjugate made up of a radioluminescent molecule and one photosensitizer, the radioluminescent molecule being suitable for absorbing an x-ray with energy higher than an absorption threshold and for emitting luminescent radiation in the visible domain, and the photosensitizer being suitable for absorbing the luminescent radiation and producing singlet oxygen. The radioluminescent compound is made up of a molecule of lanthanide chloride (lncl3); the photosensitizer is selected among the following photosensitizers: al(iii)phthalocyanine, mthpc, chlorin e6 (ce6), hypericin, hypocrellin, nile blue, oxazine 170, oxazine 1, protoporphyrin ix, 7-methoxycoumarin-4-acetic acid, bacteriochlorophyll, and auramin; and the photosensitizer is selected such as to maximize the energy transfer between an x-ray absorbed by the radioluminescent lanthanide 2 and the photosensitizer in order to produce singlet oxygen..
Photochemical reaction device, manufacturing same, and photochemical reaction method
To provide a photochemical reactor that allows a photochemical reaction to proceed in the atmospheric air. Used is porous glass that is permeable to light in such a wavelength region as to be absorbable by photosensitizer.
National Institute Of Advanced Industrial Science And Technology
A crosslinking control system, the use of the crosslinking control system, a laser system comprising the crosslinking control system, a crosslinking control method and a method for laser treatment are provided. The crosslinking control system comprises a photosensitizer providing unit, a light source configured to provide light having a wavelength suitable to activate the photosensitizer introduced into or applied onto the tissue for crosslinking, and a control computer..
Prostate-specific membrane antigen-targeted photosensitizers for photodynamic therapy
Urea-based photosensitizers, which target prostate-specific membrane antigen (psma) for imaging and targeted therapy of psma-expressing tumors and cancers are disclosed.. .
The Johns Hopkins University
Immunoassays employing non-particulate chemiluminescent reagent
Methods and reagents are disclosed for conducting assays. Embodiments of the present methods and reagents are concerned with chemiluminescent reagents for determining the presence and/or amount of an analyte in a sample suspected of containing the analyte.
Siemens Healthcare Diagnostics Inc.
Methods of altering optical power of a lens
Methods and devices for altering the power of a lens, such as an intraocular lens, are disclosed. In one method, the lens comprises a polymer matrix containing photobleachable chromophores and a radical scavenger dispersed in the polymer matrix.
Battelle Memorial Institute
Photopolymerizable compositions featuring novel amine accelerator for improved color stability and reduced polymerization stress thereby
R2 and r3 are each independently alkyl having from 1 to 5 carbon atoms; r and r1 are each independently hydrogen or halogen; alkyl, alkoxy, or alkylthio having from 1 to 18 carbon atoms; or phenyl and/or substituted phenyl alkoxy, or alkylthio having from 1 to 18 carbon atoms. It can be used in part with conventional photosensitizers and radically polymerizable monomers..
Inverted solar cell and process for producing the same
The present invention relates to a method for producing a solid solar cells, including the steps of providing a hole collector layer, applying a conductive layer onto the hole collector layer, applying an electron blocking layer onto the conductive layer, applying a sensitizer layer onto the electron blocking layer, applying a hole blocking layer onto the sensitizer layer, and providing a current collector and/or a metal layer or a conductor. The sensitizer layer including an organic-inorganic perovskite is applied by co-deposition of one or more sublimated divalent or trivalent salts and of one or more sublimated organic ammonium salts to obtain the organic-inorganic perovskite.
Universitat De Valencia
Semiconductor device and manufacturing the same
According to one embodiment, a method of manufacturing a semiconductor device, includes forming an energy-ray-curable resin layer containing a sensitizer for increasing sensitivity to exposure light, on an underlayer region including a semiconductor substrate, irradiating the energy-ray-curable resin layer with energy rays to form a lower layer film containing the sensitizer, forming a resist film on the lower layer film, diffusing the sensitizer from the lower layer film into the resist film by thermal treatment, irradiating the resist film in which the sensitizer is diffused with exposure light, and developing the resist film irradiated with the exposure light.. .
Kabushiki Kaisha Toshiba
Antimicrobial compositions made of a thermoplastic polymer and a photosensitizer
Compositions comprising a polymeric matrix made of a thermoplastic polymer and a photosensitizer incorporated in the polymeric matrix are provided. Also provided are processes of preparing the compositions, without using an organic solvent or a surfactant.
Ariel-university Research And Development Company Ltd.
Polymeric forms of h-nox proteins
The invention provides polymeric h-nox proteins for the delivery of oxygen with longer circulation half-lives compared to monomeric h-nox proteins. Polymeric h-nox proteins extravasate into and preferentially accumulate in tumor tissue for sustained delivery of oxygen.
Arsenic-based treatment of cancers and inflammatory disorders
In one embodiment, the invention provides a method of treating a subject who suffers from a cancer (particularly a chemotherapeutic or radiotherapeutic-resistant cancer) or from an inflammatory disorder, the method comprising co-administering to the subject a pharmaceutically-effective amount of: (a) one or more elements or compounds selected from the group consisting of arsenic, an arsenite and arsenic trioxide (ato); and optionally (b) at least one anticancer agent (preferably a dna damaging agent); and/or (c) at least one or more poly(adp-ribose) polymerase (parp) inhibitors other than arsenic, an arsenite and arsenic trioxide (ato). In preferred embodiments, the arsenic for the treatment of cancer, arsenite and ato serve as radio sensitizers for concomitant radiotherapy as well as parp inhibitors.
Method of photopolymerizing of acrylates
Multiple photocured and copper electrolessly plated patterns are formed on a continuous flexible solid polymeric film in a roll-to-roll process. A photocurable composition is applied directly to the film in a patternwise fashion using flexographic printing members to form multiple patterns of the photocurable composition directly on the film.
Non-aqueous metal catalytic composition with oxyazinium photoreducing agent
A non-aqueous metal catalytic composition includes (a) a silver complex comprising reducible silver ions, (b) an oxyazinium salt silver ion photoreducing agent, (c) a hindered pyridine, (d) a photocurable component, a non-curable polymer, or combination of a photocurable component and a non-curable polymer, and (e) a photo sensitizer different from all components (a) through (d) in the non-aqueous metal catalytic composition, in an amount of at least 1 weight %. This non-aqueous metal catalytic composition can be used to form silver metal particles in situ during suitable reducing conditions.
Porphyrinoid components, water photodisinfection
The present invention relates to disinfection of water polluted by microbial pathogens through the use of photosensitizers. The photosensitizer is a porphyrinoid which is part of an adduct comprising a resin, a spacer and said porphyrinoid.
Forming catalytic sites from reducible silver complexes
A non-aqueous metal catalytic composition includes (a) a silver complex comprising reducible silver ions, (b) an organic phosphite, (c) an oxyazinium salt silver ion photoreducing agent, (d) a hindered pyridine, (e) a photocurable component, a non-curable polymer, or combination of a photocurable component and a non-curable polymer, and (f) a photosensitizer different from all components (a) through (e) in the non-aqueous metal catalytic composition, in an amount of at least 1 weight %. This non-aqueous metal catalytic composition can be used to form silver metal particles in situ during suitable reducing conditions.
Non-aqueous metal catalytic composition with oxyazinium photoreducing agent
A non-aqueous metal catalytic composition includes (a) a silver complex comprising reducible silver ions, (b) an organic phosphite, (c) an oxyazinium salt silver ion photoreducing agent, (d) a hindered pyridine, (e) a photocurable component, a non-curable polymer, or combination of a photocurable component and a non-curable polymer, and (f) a photo sensitizer different from all components (a) through (e) in the non-aqueous metal catalytic composition, in an amount of at least 1 weight %. This non-aqueous metal catalytic composition can be used to form silver metal particles in situ during suitable reducing conditions.