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Sclera patents

      

This page is updated frequently with new Sclera-related patent applications.




new patent (bacterio)chlorophyll photosensitizers for treatment of eye diseases and disorders
An ophthalmic composition is provided, comprising chlorophyll or bacteriochlorophyll compounds for photodynamic treatment (pdt) of diseases, disorders and conditions associated with corneal or scleral anomalies, such as corneal thinning and scleral stretching.. .
Yeda Research And Development Co. Ltd.


new patent Ocular iontophoresis device
The invention concerns an ocular iontophoresis device for delivering at least one active substance to an eyeball, comprising: a wall defining a tubular-shaped body delimitating laterally a reservoir configured for receiving the active substance(s), the wall comprising a circular distal end configured for being positioned on an ocular surface of the eyeball and surrounding the cornea and a part of the sclera of the eyeball, a first electrode configured to be positioned in front of the sclera, said first electrode being configured for delivering a first current density to the active substance(s) of the reservoir, the first electrode defining an annular-shaped first surface that is arranged in a peripheral part of the reservoir, a second electrode configured to be positioned in front of the cornea, said second electrode being configured for delivering a second current density to the active substance(s) of the reservoir, the second electrode defining a disk-shaped second surface that is arranged in a central part of the reservoir, first and second electrodes being arranged concentrically to each other, and at least one controller for independently controlling said first and second electrodes.. .
Opia Technologies


Method for obtaining contact lenses with dynamically controlled sagitta and clearance
The disclosure generally describes methods, systems and products relating to the development and manufacture of scleral contact lenses. A number of dimensions for the scleral lens is generated based on control points and attendant curvature parameters.
Bausch & Lomb Incorporated


Light adjustable intraocular lenses using upconverting nanoparticles and near infrared (nir) light
This disclosure relates compositions comprising upconverting nanocrystals and photoactive compositions and methods using these compositions to modify treat myopia and other ocular conditions. In some cases, the methods use near infrared irradiation to adjust the refractive power of light adjustable ocular lenses.
California Institute Of Technology


Schlemm's canal stent-sieve
An ocular stent device (100) can include an elongate arcuate body portion (102) configured in size and shape to be inserted into the schlemm's canal. The body portion (102) can be inserted along an arc of at least 100 degrees of the schlemm's canal.
University Of Utah Research Foundation


System and designing scleral lenses
A system and method for designing scleral lenses includes a computer, a camera and a lathe connected by a network. The camera captures a set of sagittal images at each of a set of sagittal planes of an eye.

Method and determining eye topology
A method and apparatus for measuring the topography of the corneal and scleral regions of the eye. The measurements provide surface contours that are useful in the manufacture of scleral contact lenses..
Eyedeal Scanning, Llc


Contact lens with multi-layered pattern
Contact lenses that comprise a multi-layer design may be utilized to enhance and/or highlight the appearance of the eyes upon which the contact lenses are positioned while maintaining a natural look. These exemplary designs each comprise three layers; namely, a unique limbal design graphic, a unique inner effect graphic and a unique outer effect graphic.
Johnson & Johnson Vision Care, Inc.


Inhibition of collagen synthesis
Therapies and compositions for reducing collagen synthesis in mammalian cells and tissues wherein the targets are scleraxis, scleraxis-binding sites, receptor-regulated smads, and/or binding sites for receptor-regulated smads whereby synergistic interactions between scleraxis proteins and receptor-regulated smads are reduced, inhibited, interfered with, stopped, and/or prevented thereby reducing, inhibiting and/or interfering with the activation of collagen 1α2 promoter thereby inhibiting collagen production in mammalian cells and tissues. Alternatively, the therapies and compositions may reduce, inhibit, interfere with, stop, and/or prevent binding of the collagen 1α2 promoter to dna thereby inhibiting expression of the collagen 1α2 gene in mammalian cells and tissues..
University Of Manitoba


Non-invasive optical measurement of blood analyte
Methods and devices for accurate noninvasive measurement of blood analyte concentrations are disclosed. In an example process, optical properties of a blood vessel proximate to the surface of an exposed body part, for example, the sclera or the backside of the eyelid, is measured.
Santec Corporation


Shunt placement through the sclera

An intraocular shunt can be placed into a human eye using a hollow shaft having a distal tip with a bevel. The hollow shaft can be advanced through the anterior chamber while the hollow shaft holds the intraocular shunt.
Aquesys, Inc.

Method and preparation and insertion of an intraocular lens into the eye of a patient

A method for insertion of an intraocular lens into the eye of a patient, the method including removably attaching loop extensions to loops of an intraocular lens prior to insertion of the intraocular lens into the eye of a patient, initially inserting into the eye of the patient the loop extensions, pulling on the loop extensions through sclerectomies formed in the sclera of the eye of the patient, inserting the intraocular lens into the eye of the patient, positioning the intraocular lens in a desired position in the eye of the patient by pulling on the loop extensions through the sclerectomies, and fixing the loops to the sclera of the eye of the patient at the sclerectomies and detaching the loop extensions from the loops.. .
Visioncare Ophthalmic Technologies Inc.

Device, functional imaging of episcleral vessels

A method for imaging episcleral vessels in an eye includes injecting the eye with a contrast agent, positioning an imaging probe proximate to a limbus of the eye, acquiring a plurality of images along a circumference of the limbus and applying a vessel segmentation algorithm to the plurality of images to quantify episcleral diameter and density in real-time. A system for imaging episcleral vessels in an eye includes a processing unit operably connected to an imaging probe and a visual feedback device.
The Regents Of The University Of California

Shape memory polymer intraocular lenses

A shape memory polymer (smp) intraocular lens may have a refractive index above 1.45, a tg between 10° c. And 60° c., inclusive, de minimis or an absence of glistening, and substantially 100% transmissivity of light in the visible spectrum.
Abbott Medical Optics Inc.

Intraocular lenses

A shape memory polymer (smp) intraocular lens may have a refractive index above 1.45, a tg between 10° c. And 60° c., inclusive, de minimis or an absence of glistening, and substantially 100% transmissivity of light in the visible spectrum.
The Regents Of The University Of Colorado

Shape memory polymer intraocular lenses

A shape memory polymer (smp) intraocular lens may have a refractive index above 1.45, a tg between 10° c. And 60° c., inclusive, de minimis or an absence of glistening, and substantially 100% transmissivity of light in the visible spectrum.
The Regents Of The University Of Colorado

Intrascleral shunt placement

Glaucoma can be treated by implanting an intraocular shunt into an eye. The eye has an anterior chamber and sclera.
Aquesys, Inc.

Shape memory polymer intraocular lenses

A shape memory polymer (smp) intraocular lens may have a refractive index above 1.45, a tg between 10° c. And 60° c., inclusive, de minimis or an absence of glistening, and substantially 100% transmissivity of light in the visible spectrum.
The Regents Of The University Of Colorado

Methods for intraocular shunt placement

Intraocular pressure can be reduced by insertion of an intraocular shunt in the eye such that it forms a drainage pathway between the anterior chamber and a region of lower pressure. A hollow shaft that holds an intraocular shunt can be advanced through the anterior chamber.
Aquesys, Inc.

System for sutureless closure of scleral perforations and other ocular tissue discontinuities

The present disclosure describes, among other things, a thermo-responsive hydrogel comprising a pnipam copolymer having adhesive properties that are temperature dependent, as well as a device for administering the hydrogel, and methods for making and using the foregoing.. .
University Of Southern California

Extraocular epiretinal implant

A visual prosthesis in the form of a retinal implant, which is distinguished by the least possible space requirement inside the eye, is achieved by a visual prosthesis having an intraocular implant and an extraocular implant, which supplies the intraocular implant with energy and controls it. Virtually all the electronic components, which do not necessarily need to be accommodated with the intraocular implant inside the eye, can be arranged outside the eyeball, for example on the sclera.
Pixium Vision Sa

Device for ocular access

The present invention provides devices to access the suprachoroidal space or sub-retinal space in an eye via a minimally invasive transconjunctival approach. The devices may also be used after a partial dissection, for example after dissection of the outer scleral layer of the eye, and using the device within the dissection to access the suprachoroidal space or the sub-retinal space..
Clearside Biomedical, Inc.

Scleral prosthesis for treating presbyopia and other eye disorders and related devices and methods

A scleral prosthesis includes an elongated body configured to be implanted into scleral tissue of an eye. The elongated body includes (i) opposing first and second ends and (ii) multiple first portions that form the first end of the body and part of a remainder of the body between the ends.
Refocus Group, Inc.

Scleral prosthesis for treating presbyopia and other eye disorders and related devices and methods

A scleral prosthesis includes an elongated body configured to be implanted into scleral tissue of an eye. The elongated body includes opposing first and second ends.
Refocus Group, Inc.

Scleral prosthesis for treating presbyopia and other eye disorders and related devices and methods

A scleral prosthesis includes an elongated body configured to be implanted into scleral tissue of an eye. The elongated body includes (i) opposing first and second ends and (ii) multiple first portions that form the first end of the body and part of a remainder of the body between the first and second ends.
Refocus Group, Inc.

Ophthalmic shunt and method

An ophthalmic shunt includes a seal or septum through which multiple injections of the therapeutic agent can be made as needed, thereby avoiding repeated injury to the sclera. The therapeutic agent is temporarily carried in a tube connected to the septum.
Abbott Cardiovascular Systems Inc.

Valve device for use in glaucoma surgery

A valve device for use in glaucoma surgery comprises at least one aqueous humor feeding duct (2) having a first end (2a) designed to fit into the anterior chamber of the eyeball, a balancing chamber (3) communicating with a second end (2b) of the feeding duct (2) and having an inner volume ranging from 2 mm3 to 6 mm3, and designed to be introduced into a surgical groove in the sclera, a retainer member (6) placed within the feeding duct (2) to allow fluid transfer from the first end (2a) toward the second end (2b) of the feeding duct (2) and to inhibit fluid transfer in the opposite direction. A plurality of aqueous humor outflow ducts (5) extend from the balancing chamber (3) to allow outflow of aqueous humor from the balancing chamber (3) to an outside space..

A device for delivery of compositions to the eye

The present invention discloses a device suitable for delivery of a fluid composition to an eye, especially therapeutic compositions, comprising: a hollow needle with a bore having a proximal end and a distal end, said distal end configured to pass into a passage in a sclera of an eye, said bore configured to function as a conduit for a fluid from said proximal end to said distal end, and a solid separator having a distal tip, configured to move inside said bore of said hollow needle allowing said distal tip of said separator to protrude from said distal end of said needle.. .
Tel Hashomer Medical Research Infrastructure And Services Ltd.

Visual display with illuminators for gaze tracking

A visual display includes hidden reference illuminators adapted to emit invisible light for generating corneo-scleral reflections on an eye watching a screen surface of the display. The tracking of such reflections and the pupil center provides input to gaze tracking.
Tobll Ab

Intrascleral shunt placement

Glaucoma can be treated by implanting an intraocular shunt into an eye. The eye has an anterior chamber and sclera.
Aquesys, Inc.

Optical coherence elastography to assess biomechanics and detect progression of ocular and other tissues degenerative diseases

An excitation force (internal or external) and phase-sensitive optical coherence elastography (oce) system, used in conjunction with a data analyzing algorithm, is capable of measuring and quantifying biomechanical parameters of tissues in situ and in vivo. The method was approbated and demonstrated on an example of the system that combines a pulsed ultrasound system capable of producing an acoustic radiation force on the crystalline lens surface and a phase-sensitive optical coherence tomography (oct) system for measuring the lens displacement caused by the acoustic radiation force.
University Of Houston System

Scleral translocation elasto-modulation methods and apparatus

A laser delivery system is configured to delivery light energy to soften and realign the tissue of the eye in order to increase accommodation and treat glaucoma. The laser system can be configured to increase a circumlental space of the eye and increase movement of a posterior vitreous zonule in order to increase accommodation.
Aleyegn, Inc.

Biocompatible ribbon cable with narrow folded section

A biocompatible, micro-fabricated ribbon cable is described in which at least one set of conductors diverges laterally into a bypass wing that forms an aperture through the ribbon cable. The bypass wing is folded in a line through the aperture and over a central portion of the ribbon cable, resulting in a ribbon cable with a narrow, stacked region.

Annular device

The above object is attained by preparing an annular device to be worn over the surface of the sclera, the annular device including an opening exposing the cornea and one or a plurality of approximately encircling grooves on an intermediate part between an inner rim part and an outer rim part. The annular device has a maximum thickness preferably in the intermediate part..

Transscleral drug delivery

Magnetic drug-loaded polymeric particles are used in a transscleral drug delivery method. In the synthesis process of the aforementioned magnetic drug-loaded polymeric particles, therapeutic agents, along with a magnetic agent are encapsulated in a polymer.

Use of cell-permeable peptide inhibitors of the jnk signal transduction pathway for the treatment of chronic or non-chronic inflammatory eye diseases

The present invention refers to the use of protein kinase inhibitors and more specifically to the use of inhibitors of the protein kinase c-jun amino terminal kinase, jnk inhibitor (poly-)peptides, chimeric peptides, or of nucleic acids encoding same as well as pharmaceutical compositions containing same, for the treatment of non-chronic or chronic inflammatory eye diseases, such as inflammatory diseases of the blephara, conjunctiva, cornea, sclera, the vitreous body, uvea, ciliary body, choroid, orbital bone, lacrimal gland, or iris, in particular wherein the inflammatory disease is selected from hordeolum, chalazion, conjunktivitis, keratitis, scieritis, episcleritis, endophthalmitis, panophtalmitis, irititis, uveitis, cyclitis, chorioiditis, orbital phlegmon, and myositis of the eye muscle etc.. .
Xigen Inflammation Ltd.

Motorized suprachoroidal injection of therapeutic agent

An apparatus for delivering therapeutic agent to an eye comprises a body, a cannula, a hollow needle, and an automated actuation assembly. The cannula extends distally from the body and is sized and configured to be insertable between a choroid and a sclera of a patient's eye.
Janssen Research & Development, Llc

Method and sensing position between layers of an eye

An apparatus for delivering therapeutic agent to an eye comprises a body, a cannula, a hollow needle, an actuation assembly, and a detection/visualization system. The cannula extends distally from the body and is sized and configured to be insertable between a choroid and a sclera of a patient's eye.
Janssen Research & Development, Llc

Therapeutic agent delivery device with advanceable cannula and needle

An apparatus for delivering therapeutic agent to an eye comprises a body, a cannula, a hollow needle, a cannula actuation assembly, and a needle actuation assembly. The cannula extends distally from the body and is sized and configured to be insertable between a choroid and a sclera of a patient's eye.
Janssen Research & Development, Llc

Pharmaceutical composition and uses thereof

Pharmaceutical compositions containing a combination of anti-chondrogenesis agents are disclosed. Methods of reducing scleral chondrogensis, reducing one or more ocular chondrogenic proteins, reducing inflammation induced chondrogensis and treating myopia by administering an effective amount of one or more anti-chondrogensis agents are also provided.
Kaohsiung Chang Gung Memorial Hospital

Cannula insertion sustaining systems and devices

A cannula device for an ophthalmic surgical procedure includes a cannula configured to be inserted through a sclera of an eye and a disk structure configured to apply a force on the sclera to sustain a position of the cannula. A cannula insertion sustaining system for an ophthalmic procedure includes a cannula tube configured to be inserted through a sclera of an eye, an upper tube portion, and a connector tube coupled to the upper tube portion and to the cannula tube.
Doheny Eye Institute

Systems and methods for delivering an ocular implant to the suprachoroidal space within an eye

Delivery devices, systems and methods are provided for inserting an implant into an eye. The delivery or inserter devices or systems can be used to dispose or implant an ocular stent or implant, such as a shunt, in communication with a suprachoroidal space of the eye.
Glaukos Corporation

Medical device intended for the long-term storage of a cornea, or for ex vivo experimentation on a human or animal cornea

A device for the storage of a corneal specimen has means for the reception and entrapment of a corneal specimen, connected to the means for the creation of a pressure gradient with overpressure on the endothelial side and to the preservation medium circulation means in the layouts that present the means for the reception and entrapment of the cornea specimen. The means for the reception and entrapment of the corneal specimen entrap the sclera ciliary zone surrounding the cornea in an airtight manner to delimit a separate endothelial chamber and epithelial chamber in which the preservation medium can circulate with an overpressure in the endothelial chamber; the intermediate component and the endothelial lid comprise inlet and outlet orifices for the preservation medium which are connected to the means for the circulation of the preservation medium and the creation of a pressure gradient between the endothelial chamber and the epithelial chamber with overpressure in the endothelial chamber..
Etablissement Francais Du Sang

Multispectral eye analysis for identity authentication

Certain aspects relate to systems and techniques for generating high resolution iris templates and for detecting spoofs, enabling more reliable and secure iris authentication. Pairs of rgb and nir images can be captured by the iris authentication system for use in iris authentication, for example using an nir led flash and a four-channel image sensor.
Qualcomm Incorporated

Multispectral eye analysis for identity authentication

Certain aspects relate to systems and techniques for generating high resolution iris templates and for detecting spoofs, enabling more reliable and secure iris authentication. Pairs of rgb and nir images can be captured by the iris authentication system for use in iris authentication, for example using an nir led flash and a four-channel image sensor.
Qualcomm Incorporated

Ocular drug delivery system

An ocular drug delivery system can include a composition in which a formulation including recombinant human growth hormone (rhgh) is contained in a polymer matrix. The composition is configured for placement in or on the eye of a subject, and provides controlled release of an amount of the rhgh to the eye effective to promote healing of a conjunctival, sclera and or corneal wound..
Jade Therapeutics, Inc.

Presbyopic vision correction with controlled 3-d patterned mechanical weakening of scleral tissue

Treatments to improve ocular conditions such as presbyopia are provided. Structural (mechanical) weakening of the sclera is accomplished through the formation of a 3-d pattern of laser foci in the sclera resulting in an increase in the range of ocular accommodation..
Eos Holdings, Llc

Methods and devices for implantation of intraocular pressure sensors

Methods and devices for implanting an intra-ocular pressure sensor within an eye of a patient are provided herein. Methods include penetrating a conjunctiva and sclera with a distal tip of a fluid-filled syringe and positioning the pressure sensor within a vitreous body of the eye by injecting the sensor device through the distal tip.

Devices and methods to provide hands free scleral depression during ophthalmic procedures

The devices and methods of the present invention provide a means to depress the sclera in such a fashion as to provide single point, multiple point, semicircular or 360° circumferential scleral tissue depression without the need for manual manipulation of the scleral depressor. The device comprises a shaped depressor for insertion between the sclera and the orbit of the eye and a holding means for positioning the depressor.



Sclera topics:
  • Anterior Chamber
  • Conjunctiva
  • Aqueous Humor
  • Epithelium
  • Accommodation
  • Ocular Hypertension
  • Brachytherapy
  • Radionuclide
  • Hypertension
  • Laser Treatment
  • Retraction
  • Vision Loss
  • Presbyopia
  • Treatments
  • Cataract Surgery


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    This listing is a sample listing of patent applications related to Sclera for is only meant as a recent sample of applications filed, not a comprehensive history. There may be associated servicemarks and trademarks related to these patents. Please check with patent attorney if you need further assistance or plan to use for business purposes. This patent data is also published to the public by the USPTO and available for free on their website. Note that there may be alternative spellings for Sclera with additional patents listed. Browse our RSS directory or Search for other possible listings.


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