Popular terms

Scaffold topics
Nucleotide
Recombinant
Polynucleotide
Amino Acid
Biodegradable
Encapsulation
Surfactant
Enhancement
Monoclonal Antibody
Polypeptide
Immunogenic
Amino Acid Sequence
Monoclonal
Interleukin 2
Immune Disease

Follow us on Twitter
twitter icon@FreshPatents

Web & Computing
Cloud Computing
Ecommerce
Search patents
Smartphone patents
Social Media patents
Video patents
Website patents
Web Server
Android patents
Copyright patents
Database patents
Programming patents
Wearable Computing
Webcam patents

Web Companies
Apple patents
Google patents
Adobe patents
Ebay patents
Oracle patents
Yahoo patents

[SEARCH]

Scaffold patents



      

This page is updated frequently with new Scaffold-related patent applications.




Date/App# patent app List of recent Scaffold-related patents
04/07/16
20160097027 
 Engineering of a novel breast tumor microenvironment on a microfluidic chip patent thumbnailEngineering of a novel breast tumor microenvironment on a microfluidic chip
A microfluidic device for more accurately modeling the in vitro environment in which cancer occurs is disclosed. The device comprises a surface defining one or more microfluidic channels that may further comprise one or more endothelial cells, a first three dimensional scaffold comprising one or more cancer cells that is spatially separated from the one or more microfluidic channels, and a second three dimensional scaffold comprising one or more stromal cells, at least a portion of which is interposed between the one or more microfluidic channels and the first three dimensional scaffold.

04/07/16
20160095958 
 Bone regeneration using stromal vascular fraction, platelet-derived growth factor-rich hydrogel, three-dimensional printed poly-epsilon-caprolactone scaffolds patent thumbnailBone regeneration using stromal vascular fraction, platelet-derived growth factor-rich hydrogel, three-dimensional printed poly-epsilon-caprolactone scaffolds
The presently disclosed subject matter focuses on recapitulating the heterotypic interactions needed to maximize the co-development of vasculature and bone. More particularly, the presently disclosed subject matter explores the potential of cellular aggregation and temporal presentation of factors to induce the cell-cell signaling events required to stimulate ascs to self-organize into vascularized bone.
The Johns Hopkins University


04/07/16
20160095730 
 Devices and systems for gastric volume control patent thumbnailDevices and systems for gastric volume control
A gastric balloon includes a scaffold structure, one or more internal inflatable compartments within the scaffold structure, and one or more inflatable bladders formed over the space-filling compartment. The gastric balloon may be deployed transesophageally using a gastroscope and is inflated in situ, preferably using a combination of liquid and gas inflation media..
Fulfillium, Inc.


04/07/16
20160095727 
 Stent with elongating struts patent thumbnailStent with elongating struts
A stent includes a plurality of rings which form a tubular scaffold. The rings include an elongation mechanism which allows for further expansion of the stent..
Abbott Cardiovascular Systems Inc.


04/07/16
20160095724 
 Controlled ingrowth feature for antimigration patent thumbnailControlled ingrowth feature for antimigration
A tubular prosthesis that includes a scaffolding formed by at least one scaffolding filament; a cover; and at least one controlled ingrowth feature constructed and arranged to abut an inner surface of a lumen wall when the prosthesis is implanted in the body lumen. The controlled ingrowth feature may extend inwards or outwards from the prosthesis outer surface.
Boston Scientific Scimed, Inc.


04/07/16
20160095695 
 Silk fibroin hydrogels and uses thereof patent thumbnailSilk fibroin hydrogels and uses thereof
The present specification provides for methods for purifying fibroins, purified fibroins, methods of conjugating biological and synthetic molecules to fibroins, fibroins conjugated to such molecules, methods of making fibroin hydrogels, fibroin hydrogels and fibroin hydrogel formulations useful for a variety of medical uses, including, without limitation uses as bulking agents, tissue space fillers, templates for tissue reconstruction or regeneration, cell culture scaffolds for tissue engineering and for disease models, surface coating to improve medical device function, or drug delivery devices.. .
Allergan, Inc.


04/07/16
20160095316 
 Compositions and methods for the removal of biofilms patent thumbnailCompositions and methods for the removal of biofilms
Methods of breaking down a biofilm or inhibiting, preventing or treating a microbial infection that produces a biofilm are disclosed, which involves administration of a polypeptide that has one or more hmg-box domains to a subject suffering from the infection or having the biofilm. By competing with microbial proteins that bind to dna scaffold in the biofilm, these polypeptides destabilize the biofilm leading to destruction and removal of the biofilm by the immune system..

03/31/16
20160091489 
 Devices and methods for isolating cells patent thumbnailDevices and methods for isolating cells
The subject invention pertains to devices and methods of isolating target cells from a population of cells. The devices comprise of one or more microfluidic channels and scaffolding particles conjugated with one or more ligands that bind to the target cells.
University Of Florida Research Foundation, Incorporated


03/31/16
20160090400 
 Antibody like protein patent thumbnailAntibody like protein
A general method and recombinant nucleic acid sequences, by means which the method selects a recombinant protein containing an fha domain for binding a target molecule from a library proteins with a high-throughput method of creating protein variations within the fha domain in non-conserved or non-structural sequences of the fha scaffold, and the library may also be in the form of a phagemid or phage library wherein the alp nucleic acid sequence is inserted into a vector capable of allowing the vector and expressed alp protein from being virally packaged, and the recombinant nucleic acid sequences which are randomly mutated at varying non-conserved or non-structural fha domain sequences.. .

03/31/16
20160089825 
 Cellular materials based molds with lower cycle time patent thumbnailCellular materials based molds with lower cycle time
A mold comprising a scaffolding support structure including a base member, a top member and side members defining an enclosure. The scaffolding structure further includes a plurality of interconnected and elongated support members interspersed within the enclosure between the base member and the top member so as to define open space within the enclosure for ease of heating and cooling fluid flow, and a plurality of flow partitions within the enclosure.
Gm Global Technology Operations Llc


03/31/16
20160089253 

Bioabsorbable polymeric medical device


In embodiments there is described a cardiovascular tube-shaped lockable and expandable bioabsorbable scaffold having a low immunogenicity manufactured from a crystallizable bioabsorbable polymer composition or blend.. .
Orbusneich Medical Inc.


03/24/16
20160084769 

Fluorescent caffeine sensor and portable kit and microfluidics device for caffeine detection


The present invention relates to caffeine orange, a novel aqueous-phase fluorescence turn-on sensor for caffeine that is structurally based on a bodipy-scaffold. The present invention further provides for methods of detecting and measuring caffeine in aqueous media.
Ulsan National Institute Of Science And Technology


03/24/16
20160083968 

Safety platform scaffold apparatus


A portable safety platform scaffold apparatus includes a plurality of wall-supportable units for being supported by the top portion of a wall. The wall support units each include a wall-top engagement portion, a common removable floor member, and a common removable fence.

03/24/16
20160083692 

Electroactive polymeric scaffolds and delivering nerve growth factor to nerve tissue


A polymerizable unit that yields an electrochemically responsive polymer (advantageously pyrrole) is anchored by polymerization within a polycaprolactone matrix to form an electroactive scaffold upon which cells can be cultured and in which the micro- and nano-topological features of the polycaprolactone matrix are preserved. A scaffold manufactured in accordance with the preferred embodiment can support schwann cells, which produce nerve growth factor when electrically stimulated.
University Of Florida Research Foundation, Incorporated


03/24/16
20160083682 

Unitary 3d culture device


A continuous device for culturing mammalian cells in a three-dimensional structure for the transplantation or implantation in vivo is described. The culturing device comprises (a) a scaffold formed by a matrix of interconnected growth surfaces spaced at regular intervals and (b) a fluid distribution means at the inlet and the exit of the growth areas.
Vivabiocell S.p.a.


03/24/16
20160083450 

Human protein scaffold with controlled serum pharmacokinetics


This invention provides constructs comprising a protein scaffold, wherein the scaffold comprises domain iii, domain iiia, or domain iiib of human serum albumin or a polypeptide having substantial sequence identity to the domain iii, the domain iiia, or the domain iiib; and a targeting moiety in covalent linkage to the protein scaffold; and a therapeutic moiety and/or an imaging moiety in covalent linkage to the protein scaffold. The scaffold can be modified to tune the serum pharmacokinetics of the construct.
The Regents Of The University Of California


03/24/16
20160083344 

Compound based on cyanine scaffold for diagnosis sepsis by selectively detect glutathione


The present invention relates to a compound based on cyanine scaffold for diagnosing sepsis by selectively detecting glutathione. The compound based on cyanine scaffold according to the present invention has the advantages of maintaining its structure in intracellular environment and of reacting selectively to glutathione only among many amino acids containing thiol group (r—sh) such as cysteine, homocysteine, and glutathione, to produce changes in absorption or fluorescence spectrum, making the compound useful for the detection of in vivo glutathione in biosamples and also for the diagnosis of sepsis characteristically displaying the changes of glutathione concentration..
Ewha University - Industry Collaboration Foundation


03/24/16
20160082136 

Metal complexes and fluorination thereof


A method of labelling biological molecules with 18f, via attachment of fluorine to a metal complex, where the metal complex is conjugated to the biological molecule. The invention highlights the incorporation of hydrogen bonding (h-bonding) into the metal complex scaffold, and how this can be utilised to improve the kinetics of fluoride incorporation.
University Of Southampton


03/24/16
20160081858 

Compositions and methods for the prevention of scarring and/or promotion of wound healing


The present disclosure provides methods of preventing and/or reducing scar contracture and methods of promoting wound healing by utilizing an electrospun biocompatible scaffold.. .
Duke University


03/24/16
20160081831 

Devices and systems for gastric volume control


A gastric balloon includes a scaffold structure, one or more internal inflatable compartments within the scaffold structure, and one or more inflatable bladders formed over the space-filling compartment. The gastric balloon may be deployed transesophageally using a gastroscope and is inflated in situ, preferably using a combination of liquid and gas inflation media..
Fulfillium, Inc.


03/24/16
20160081827 

Thermal processing of polymer scaffolds


Methods are disclosed including thermally processing a scaffold to increase the radial strength of the scaffold when the scaffold is deployed from a crimped state to a deployed state such as a nominal deployment diameter. The thermal processing may further maintain or increase the expansion capability of the scaffold when expanded beyond the nominal diameter..
Abbott Cardiovascular Systems Inc.


03/24/16
20160081824 

Crimping polymer scaffolds


A polymer scaffold is crimped to a balloon while the polymer material is in a thermodynamically unstable state, or a transient state including crimping shortly after a tube or scaffold processing step that imparts memory to the material, or shortly after rejuvenation of the scaffold.. .
Abbott Cardiovascular Systems Inc.


03/24/16
20160081807 

Articular cartilage repair


A scaffold is provided which facilitates integration of both bone and cartilage at an osteochondral lesion, thereby acting as a tissue engineered interface or tissue engineered junction between the two different tissues. The method and systems for engineering this interface may be acellular or may be loaded with cells prior to use..
Cytex Therapeutics, Inc.


03/17/16
20160080857 

Three-dimensional air-adsorbing structure


A three-dimensional air-adsorbing structure. The structure has a three-dimensional, unitary, skeletal, porous scaffold, air-adsorbing material particles, and one or more hydrophobic binders that couple air-adsorbing material particles to each other to form agglomerates and couples particles and agglomerates to the scaffold.
Bose Corporation


03/17/16
20160075987 

Novel 3d scaffold microstructure


A three-dimensional scaffold microstructure comprising a plurality of collapsed polymer columns for use in cell culture or nematode studies.. .
King Abdullah University Of Science And Technology


03/17/16
20160075746 

Tailoring multivalent interactions of biopolymers with a polyproline scaffold


A glycopeptide, comprising a polyproline backbone and one or more carbohydrate molecules.. .
Agency For Science, Technology And Research


03/17/16
20160075668 

Bicyclic methylene aziridines and reactions thereof


The oxidative functionalization of olefins is a common method for the formation of vicinal carbon-heteroatom bonds. However, oxidative methods to transform allenes into synthetic motifs containing three contiguous carbon-heteroatom bonds are much less developed.
Wisconsin Alumni Research Foundation


03/17/16
20160074540 

Metal complexes and their fluorination


A method of labelling biological molecules with 18f, via attachment of fluorine to a metal complex, where the metal complex is conjugated to the biological molecule. The invention highlights the incorporation of hydrogen bonding (h-bonding) into the metal complex scaffold, and how this can be utilised to improve the kinetics of fluoride incorporation.
University Of Southampton


03/17/16
20160073708 

Wearable inflating system and automatically arresting falls through gaps in structures, and use


An inflatable fall arrest and fall protection safety system generally having one or more inflatable apparatus attached to a belt or other suitable wearable support structure that can be worn by a user. When the user falls, one or more directional inertia activated inflation devices trigger one or more inflators to inflate the one or more inflatable apparatus such that they protect the falling user in the given situation.

03/10/16
20160069095 

Self-jacking scaffold for large cylindrical tanks


An apparatus and method for raising a self-jacking scaffold system including extending a jacking screw and jacking screw bracket axially upward, connecting a jacking screw bracket to an overhead tank bracket for a plurality of scaffold sections coupled to a jacking assembly, detaching a plurality of scaffold mounting brackets from a plurality of tank mounting brackets, raising the continuously coupled plurality of scaffold sections, and reattaching the plurality of scaffold mounting brackets to a plurality of tank mounting brackets. Noting the plurality of scaffold sections is continuously coupled proximate a circumference of a shell tank, the continuously coupled scaffold sections and tank mounting brackets provide stiffness to the tank shell to enable it to resist external loads and can be quickly moved and restored as required during tank construction..
Om Engineering


03/10/16
20160067375 

3d biomimetic, bi-phasic key featured scaffold for osteochondral repair


This invention describes methods for the creation of 3d biologically inspired tissue engineered scaffolds with both excellent interfacial mechanical properties, and biocompatibility and products created using such methods. In some cases, a combination of nanomaterials, nano/microfabrication methods and 3d printing can be employed to create structures that promote tissue reconstruction and/or production.
The George Washington University, A Congressionally Chartered Not-for-profit Corporati


03/10/16
20160067353 

Protein-polymer-drug conjugates


A drug conjugate is provided herein. The conjugate comprises a protein based recognition-molecule (pbrm) and a polymeric carrier substituted with one or more -ld-d, the protein based recognition-molecule being connected to the polymeric carrier by lp.
Mersana Therapeutics, Inc.


03/10/16
20160067190 

Injectable nano-network gels for diabetes treatment


A system for “smart” delivery of a therapeutic, prophylactic or diagnostic agent, such as glucose-mediated delivery of insulin through an injectable nano-network consisting of oppositely-charged dextran nanoparticles encapsulating insulin and glucose-specific enzymes forming a gel-like 3d scaffold. As demonstrated by the examples, the system effectively dissociates to release insulin in a hyperglycemic condition, where the catalytic conversion of glucose into gluconic acid and the subsequent degradation of polymeric matrix are facilitated.
The Children's Medical Center Corporation


03/10/16
20160067070 

Bioerodible polymeric stent scaffolding pattern


A stent includes a tubular network of struts cut from a bioerodible polymer tube. The tubular network includes a plurality of bands and a plurality of connectors.
Boston Scientific Scimed, Inc.


03/03/16
20160064789 

Battery resetting process for scaffold fuel electrode


An electrochemical cell includes a fuel electrode configured to operate as an anode to oxidize a fuel when connected to a load. The cell also includes an oxidant electrode configured to operate as a cathode to reduce oxygen when connected to the load.
Fluidlc, Inc.


03/03/16
20160060392 

Biodegradable network polymers for regenerative medicine and tissue engineering


The disclosure relates to biodegradable polyether network polymers crosslinked via ester linkages, to substrates, implants and scaffolds comprising the biodegradable polyether network polymers, to methods for preparing such network polymers, implants and scaffolds, and to methods of using substrates, implants and scaffolds comprising the network polymers, particularly for culturing cells and regenerating tissue.. .
The University Of Melbourne


03/03/16
20160058912 

Scaffolds for promoting calcified cartilage and/or bone formation


Biomimetic hydrogel and selected ceramic interface scaffolds useful in regenerating calcified cartilage and promoting stable and integrative cartilage repair are provided. An aspect of this application relates to scaffolds for promoting calcified cartilage and/or bone formation.
The Trustees Of Columbia University In The City Of New York


03/03/16
20160058911 

Multi-step fabricating tissue engineering bone


A multi-step method for fabricating a tissue engineering bone comprises the following steps: (1) scaffold repair and pre-vascularization: fabricating a tissue engineering bone scaffold at a bone defect site, and conducting pre-vascularization; and (2) post-implantation of a seed cell for bone tissue engineering: after an inflammatory reaction period, combined with time for micro-vessel in-growth, implanting an osteogenic-induced seed cell into a tissue engineering bone scaffold at the bone defect site. In certain embodiments, the step (2) of post-implantation of a seed cell for bone tissue engineering is performed 7 to 14 days after the step (1) of scaffold repair and pre-vascularization.
Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School Of Medicine


03/03/16
20160058871 

Novel peptide complexes


The invention relates to novel self-assembling peptide complexes comprising a charged peptide and a polysaccharide, methods of producing them and uses therefor. The novel self-assembling peptide complexes of the present invention have particular utility in the restoration of biomechanical or biochemical function of a variety of biological tissues, for example and without limitation, in degenerated spinal discs, osteoarthritic joints, damaged cartilage, meniscus, ligaments, tendons, dental, ophthalmic and cardiovascular and blood vessel tissues.
University Of Leeds


03/03/16
20160058861 

Photosynthetic cellular substances and methods of use thereof


Systems and methods for developing and applying photosynthetic cellular substances to a human or animal for medical, therapeutic or cosmetic uses are provided. Photosynthetic cells, such as algal cells, can be used in these substances to provide the ability to continuously generate oxygen when exposed to a light source or other oxygen-generating trigger.
Symbiox, Inc.


03/03/16
20160058796 

Retina extracellular matrix based biomaterial


The present technology relates to compositions and methods useful for preventing and treating degenerative eye diseases or disorders. The compositions and methods include ocular biomaterials.
Northeastern University


02/25/16
20160056474 

Design, use and fabrication of microscaffolds and nanoscaffolds


A scaffold includes struts that intersect at nodes. In some instances, a cross section of the cores has at least one dimension less than 100 microns.
California Institute Of Technology


02/25/16
20160053538 

Platform unit for use with scaffolding structure


A platform unit used with a scaffolding structure includes a worker's platform and a ladder for climbing onto the worker's platform. The platform unit includes a first tipping prevention member adapted to interact with a substantially horizontal longitudinally extending first support member, and a second tipping prevention member adapted to interact from below with a substantially horizontal longitudinally extending second support member.
Pluseight Technology Ab


02/25/16
20160053231 

Two and three dimensional decellularized ecm constructs and uses therefor


A microfabricated multi-tissue system for in vitro drug toxicity testing having a plurality of layers, each of which is formed of decellularized tissue extracellular matrix (ecm) including parenchymal cells and non-parenchymal cells attached thereto. Also disclosed is a method for producing a decellularized ecm paste, and methods for producing an ecm construct and a porous 3-d scaffold from the decellularized ecm paste..
Tufts University


02/25/16
20160051728 

Decellularized adipose tissue


This invention provides a method for decellularizing adipose tissue, comprising subjecting the adipose tissue to one or more incubations in an enzymatic digestion solution containing one or more enzymes, and one or more solvent extractions, wherein decellularized adipose tissue comprising an extracellular matrix with well-preserved three-dimensional structure is obtained. The invention also provides a decellularized adipose tissue comprising an extracellular matrix with well-preserved three-dimensional architecture, and bioscaffolds, microcarrier beads, and coatings comprising the decellularized adipose tissue..
Queen's University At Kingston


02/25/16
20160051726 

Collagenous foam materials


Provided is a foam material, comprising a plurality of substantially collagenous beads, wherein the foam material is a bead foam, and wherein adjacent collagenous beads are fused together by a network of collagen fibres. Also provided are methods for preparation of foam materials comprising a plurality of substantially collagenous beads.
Queen's University At Kingston


02/18/16
20160049678 

New the fabrication of homogenous blends of polystyrenesulfonic acid and polyvinylidene fluoride suitable for the application in direct oxidation methanol fuel cells (dmfcs)


A membrane electrode assembly includes an anode catalyst layer, a cathode catalyst layer, and a polymeric blend proton exchange membrane interposed between the anode catalyst layer and the cathode catalyst layer. The polymeric blend proton exchange membrane includes a scaffold polymer and a polyacid polymer.
University Of Southern California


02/18/16
20160047132 

Structural arrangement and securing scaffolding to a building wall


A structural arrangement for securing scaffolding to a building wall. The structural arrangement includes the building wall with a recess, a façade anchor secured to the building wall and having a receptacle for accommodating at least one securing element.
Wessendorf Systembeschichtungen Gmbh


02/18/16
20160046932 

Site-specific induction of bimolecular quadruplex-duplex hybrids and methods of using the same


A method for the generation of a g-quadruplex structure on a target nucleic acid sequence is presented. The approach combines the specificity of watson-crick base pair with the stability associated with a robust g-quadruplex scaffold.
Nanyang Technological University


02/18/16
20160046928 

Structured peptide processing


The invention relates to a method for modifying one or more peptide ligands, comprising polypeptides covalently linked to a molecular scaffold at two or more amino acid residues, comprising the steps of providing one or more peptide ligands, wherein the polypeptide comprises two or more reactive groups which form a covalent linkage to the molecular scaffold, and at least one loop which comprises a sequence of two or more amino acids subtended between two of said reactive groups; exposing the peptide ligands to one or more proteases; and sorting the ligands according to the extent of proteolytic cleavage.. .
Bicycle Therapeutics Limited


02/18/16
20160046761 

Biodegradable side chain liquid crystal elastomers: smart responsive scaffolds (srs) for tissue regeneration


Controlled biodegradable smart responsive scaffold (srs) materials enhance attachment and viability of cells, i.e. Actively guiding their expansion, proliferation and in some cases differentiation, while increasing their biomechanical functionality is an important key issue for tissue regeneration.
Kent State University


02/18/16
20160046678 

Multivalent and monovalent multispecific complexes and their uses


Compositions containing multivalent and monovalent multispecific complexes having scaffolds such as antibodies that support such binding functionalities are described. The use of and methods of compositions containing multivalent and monovalent multispecific complexes having scaffolds, such as antibodies, that support such binding functionalities are also described..

02/18/16
20160046078 

Methods and computer-aided tissue engineering for modeling, design and freeform fabrication of tissue scaffolds, constructs, and devices


One aspect of the invention provides a method for multi-nozzle biopolymer deposition of heterogeneous materials to create or modify a composite biopolymer multi-part three-dimensional assembly having at least one biomimetic and at least one non-biomimetic feature. The method includes: (a) utilizing a cad environment to design and/or modify a composite multi-part assembly, thereby producing a cad design; (b) converting the cad design into a three-dimensional heterogeneous material and multi-part assembly model in a format suitable for three-dimensional, multi-nozzle printing, wherein the design comprises at least one biomimetic feature and at least one non-biomimetic feature; and (c) printing the composite assembly by simultaneously depositing the heterogeneous materials using multiple, different, specialized nozzles, wherein the simultaneous depositing includes direct deposition of cells..
Drexel University


02/18/16
20160045638 

Thermosensitive and crosslinkable polymer composite for three-dimensional soft tissue scaffold printing


A hydrogel material for use in three-dimensional scaffold printing is disclosed. The material is formed from a first triblock polymer having a formula aba and a second triblock polymer having a formula amabama, wherein a is a first polymer, b is a second polymer, and ama is a methacrylate of the first polymer.
Drexel University


02/18/16
20160045345 

Intravascular stent


Stents are provided with scaffold structures which have low exposures when implanted in arteries and other blood vessels and lumens. The cross-sectional dimensions, materials, and patterns are controlled to provide sufficient strength and coverage while maintaining the low exposure..
Elixir Medical Corporation


02/11/16
20160041182 

Fibronectin type iii repeat based protein scaffolds with alternative binding surfaces


Protein scaffolds and scaffold libraries based on a fibronectin type iii (fn3) repeat with an alternative binding surface design, isolated nucleic acids encoding the protein scaffolds, vectors, host cells, and methods of making thereof are useful in the generation of therapeutic molecules and treatment and diagnosis of diseases and disorders.. .
Janssen Biotech, Inc.


02/11/16
20160041177 

Compositions and methods for making and using oxygen sensing nanofibers and scaffolds


To address the need for scaffold-based oxygen concentration monitoring, a single-component, self-referenced oxygen sensor was made into nanofibers. Electrospinning process parameters were tuned to produce a biomaterial scaffold with specific morphological features.
University Of Virginia Patent Foundation


02/11/16
20160040320 

Method of manufacturing porous three-dimensional micro/nanofibrous scaffold using electrohydrodynamic process and porous three-dimensional micro/nanofibrous scaffold manufactured thereby


In addition, the scaffold manufactured by the manufacturing method according to the present invention has a very similar structure to an extracellular matrix (ecm), and is considerably improved in a pore structure and porosity, thereby increasing an cell attached area and enabling cells to permeate into the scaffold, and thus can provide an optimal environment for in vitro or in vivo cell growth to proliferate the cells.. .

02/11/16
20160040111 

High-throughput culture and transfer device and method


A method and device for creating hanging drop cell aggregates. The method and device includes a plurality of pegs that allow for high throughput culture of aggregates.
University Of Virginia Patent Foundation


02/11/16
20160040108 

Perfusion bioreactor with tissue flow control and live imaging compatibility


A perfusion bioreactor chamber for engineering a broad spectrum of tissues. The bioreactor allows controlled distribution of fluid through or around scaffolding materials of various shapes, structures and topologies during prolonged periods of cultivation..
The Trustees Of Columbia University In The City Of New York


02/11/16
20160040107 

Bioreactor connectors


Aspects of the disclosure relate to rotating bioreactors and articles and methods that are useful for adapting a rotating bioreactor for use with tissues or scaffolds of different sizes. In some embodiments, bioreactors comprising a reservoir and an arbor assembly are provided herein, in which the arbor assembly comprises a rotatable support to which a tissue or tissue scaffold can be attached..
Harvard Apparatus Regenerative Technology, Inc.


02/11/16
20160039909 

Fibronectin type iii domain based scaffold compositions, methods and uses


A protein scaffold based on a consensus sequence of fibronectin type iii (fn3) proteins, such as the tenth fn3 repeat from human fibronectin (human tenascin), including isolated nucleic acids that encode a protein scaffold, vectors, host cells, and methods of making and using thereof have applications in diagnostic and/or therapeutic compositions, methods and devices. In particular, protein scaffold molecules binding to igg have been identified as useful for diagnostic and/or therapeutic applications..
Janssen Biotech, Inc.


02/11/16
20160039867 

Single-chain antiparallel coiled coil proteins


The present invention relates to single-chain proteins of the formula hrs1-l1-hrs2-l2-hrs3, wherein hrs1, hrs2 and hrs3 are heptad repeat sequences and l1 and l2 are structurally flexible linker sequences, and wherein hrs1, hrs2 and hrs3 form a thermodynamically stable triple-stranded, antiparallel, alpha-helical coiled coil structure in aqueous solution. The invention also relates to amino acid sequence variants, conditions and methods to obtain such proteins and variants, and usages thereof, especially their usage as scaffolds and as therapeutic products..
Complix Nv


02/11/16
20160039766 

Cannabinoid receptor mediating compounds


A compound, or a pharmaceutically acceptable salt or ester thereof, comprising (i) a cb1 receptor mediating scaffold conjugated to (ii) a second therapeutic scaffold.. .
The United States Of America, As Represented By Th E Secretary, Department Of Health And Human Servi


02/11/16
20160038644 

Compositions for regenerating defective or absent myocardium


Compositions of the invention for regenerating defective or absent myocardium comprise an emulsified or injectable extracellular matrix composition. The composition may also include an extracellular matrix scaffold component of any formulation, and further include added cells, proteins, or other components to optimize the regenerative process and restore cardiac function..

02/11/16
20160038320 

Uniform crimping and deployment methods for polymer scaffold


A medical device-includes a scaffold crimped to a catheter having an expansion balloon. The scaffold is crimped to the balloon by a process that includes one or more balloon pressurization steps.
Abbott Cardiovascular Systems Inc.


02/11/16
20160038315 

Treatment of cardiac diseases that promote epicardial artery enlargement with bioresorbable scaffolds


Methods of treating coronary artery disease (cad) and a cardiac disease that stimulates enlargement of the epicardial artery with a bioresorbable scaffold in a patient in need thereof are disclosed. Methods of treating cad and an event that precipitates enlargement of the epicardial artery with a bioresorbable scaffold in a patient in need thereof are disclosed..
Abbott Cardiovascular Systems Inc.


02/11/16
20160038153 

Wing bifurcation reconstruction device


An intraluminal device may be used at a bifurcation to anchor in an afferent vessel, allow perfusion to efferent vessels, and act as scaffolding to inhibit herniation of objects out of a neck of a bifurcation aneurysm. An intraluminal device may include a first side; a second side opposite the first side across a longitudinal axis of the intraluminal device; a proximal section configured to anchor in an afferent vessel; a distal section comprising a first wing and a second wing wherein, in an expanded state, the first wing extends from the first side to the second side and the second wing extends from the second side, through an opening of the first wing, and to the first side..
Covidien Lp


02/04/16
20160033685 

Subwavelength coatings and methods for making and using same


Methods are disclosed for forming subwavelength coatings for use in the uv, visible, or infrared part of the electromagnetic spectrum. A first material and a second material are deposited onto a substrate.
Battelle Memorial Institute


02/04/16
20160032600 

Guard for scaffolding


Scaffolding comprising, a scaffold structure, assembled next to yet spaced from an adjacent face of a building structure with a gap therebetween, comprising a plurality of standards extending vertically adjacent the structure, horizontal ledgers extending between standards and tying the standards in a fixed interrelationship, and a platform supported from the standards and/or the ledgers thereby to be conferred a vertical support in a substantially horizontal disposition; and a guard, as a lateral extension to the platform, configured to hinge or otherwise articulate downwardly from the scaffold structure to bear onto the face of the building structure to at least partially span across the gap.. .
Wls Intellectual Property Limited


02/04/16
20160032278 

Scaffold proteins derived from plant cystatins


The present invention relates to scaffold proteins derived from plant cystatins and to nucleic acids encoding them. The scaffolds are highly stable and have the ability to display peptides.
University Of Leeds


02/04/16
20160032239 

Deterministic manufacturing process for creating 3d living tissues based on 2d directed assembly and origami techniques


A method of forming 3d engineered tissues by providing a 2d scaffold material comprising a plurality of fold locations and a plurality of cell assembly sites, assembling cells into the cell assembly sites and folding the 2d scaffold material along the fold locations to form a 3d scaffold structure. Tissues formed by the method..
Northeastern University


02/04/16
20160032073 

Polymer cellulose nanocrystal composite aerogels


Composite materials including cellulose nanocrystals incorporated into a polymer aerogel scaffold, wherein the cellulose nanocrystals serve as a reinforcement agent to result in the formation of less dense aerogels, improve the tensile mechanical properties of aerogel films, and reduce aerogel shrinkage upon thermal exposure. After gelation, the gel is dried via a suitable method such as supercritical co2 extraction, freeze drying or other method, to produce the cnc/polymer composite aerogel.
United States Government, As Represented By The Administrator Of The National Aeronautics And Spac


02/04/16
20160031939 

Modification of polypeptides


The invention provides a method for conjugating a peptide displayed on a genetic display system to a molecular scaffold performed on an ion exchange resin.. .
Bicycle Therapeutics Limited


02/04/16
20160031150 

Methods for solid phase processing of tubes and medical devices made from the processed tubes


A polymer tube is processed using a solid phase process for improving mechanical characteristics of the tube, including radial strength and stiffness. The tube is made into a scaffold possessing improved mechanical and use characteristics, such as a reduced crimped profile and improved deliverability..
Abbott Cardiovascular Systems Inc.


02/04/16
20160030908 

Titanium oxide aerogel composites


The invention relates to titanium oxide aerogels, in particular to titanium oxide binary or ternary (e.g. Titanium oxide-carbon) aerogel monoliths possessing ordered meso- and macroporosity.
Ecole Polytechnique Federale De Lausanne (epfl)


02/04/16
20160030636 

Method for decellularization of tissue grafts


The subject invention pertains to materials and methods for processing tissue to produce a natural, acellular replacement tissue that is immunocompatible with a recipient. According to the subject invention, harvested tissue is subjected to wash solutions wherein only amphoteric detergent(s) are used (e.g., anionic detergents are excluded).
University Of Florida Research Foundation, Inc.


02/04/16
20160030629 

Peptide-albumin hydrogel properties and its applications


Peptide-albumin hydrogels having a self-assembling, 3-dimensional nanofiber matrix are described. The nanofiber matrix comprises an amphiphilic peptide and albumin.
Kansas State University Research Foundation


02/04/16
20160030217 

Crush recoverable polymer scaffolds


A method of manufacturing a stent is disclosed. The stent includes a minimum crimped diameter such that in the minimum crimped diameter, a pair of stent rings, between which marker support structures reside, do not make contact with the marker support structures.
Abbott Cardiovascular Systems Inc.


02/04/16
20160030216 

Methods for crimping a polymeric scaffold to a delivery balloon and achieving stable mechanical properties in the scaffold after crimping


A medical device-includes a polymer scaffold crimped to a catheter having an expansion balloon. The scaffold is crimped to the balloon by a process that includes inflating the delivery balloon during a diameter reduction to improve scaffold retention.
Abbott Cardiovascular Systems Inc.


02/04/16
20160030214 

Methods for uniform crimping and deployment of a polymer scaffold


A medical device-includes a scaffold crimped to a catheter having an expansion balloon. The scaffold is crimped to the balloon by a process that includes one or more balloon pressurization steps.
Abbott Cardiovascular Systems Inc.


02/04/16
20160030212 

Rubber toughened bioresorbable polymer peripheral scaffolds


Bioabsorbable scaffolds are disclosed with a rigid polymer component and a rubbery polymer component. The rubbery polymer component is miscible, partially miscible, or immiscible with the rigid polymer component..
Abbott Cardiovascular Systems Inc.


01/28/16
20160026247 

Instruction system with eyetracking-based adaptive scaffolding


A digital instructional environment leverages an infrared eye-tracker to monitor a learner's reading and viewing of text and simulations for subject matter. The system detects out-of-order reading/viewing patterns that could lead to poor comprehension.
Worcester Polytechnic Institute


01/28/16
20160025125 

Locking mortise and tenon joint


This invention concerns a mortise and tenon joint of two (or more) structural members connected by a mechanical clamp (henceforth referred to as a “lock”) rather than by traditional glue, nails, screws, lag bolts, through bolts, pins, dowels and/or wedges. The design's main characteristic will apply particularly (but not exclusively) to furniture, both indoor and outdoor as well as picnic tables, work benches, scaffolding, temporary shelters or anything else which could benefit from quick and secure joinery, connection or attachment.



Scaffold topics: Nucleotide, Recombinant, Polynucleotide, Amino Acid, Biodegradable, Encapsulation, Surfactant, Enhancement, Monoclonal Antibody, Polypeptide, Immunogenic, Amino Acid Sequence, Monoclonal, Interleukin 2, Immune Disease

Follow us on Twitter
twitter icon@FreshPatents

###

This listing is a sample listing of patent applications related to Scaffold for is only meant as a recent sample of applications filed, not a comprehensive history. There may be associated servicemarks and trademarks related to these patents. Please check with patent attorney if you need further assistance or plan to use for business purposes. This patent data is also published to the public by the USPTO and available for free on their website. Note that there may be alternative spellings for Scaffold with additional patents listed. Browse our RSS directory or Search for other possible listings.


0.8657

4589

1 - 1 - 102