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Scaffold patents


This page is updated frequently with new Scaffold-related patent applications.

new patent Molecular sensor preparations and uses thereof
The present invention relates to a method of preparing a molecular sensor that is specific for a target molecule having a saccharide or peptide region. The method comprises using the target molecule as a template and incubating the template with a receptor to form a template-receptor complex.
The University Of Birmingham

new patent Low molecular weight cationic lipids for oligonucleotide delivery
The instant invention provides for novel cationic lipids that can be used in combination with other lipid components such as cholesterol and peg-lipids to form lipid nanoparticles with oligonucleotides. It is an object of the instant invention to provide a cationic lipid scaffold that demonstrates enhanced efficacy along with lower liver toxicity as a result of lower lipid levels in the liver.
Sirna Therapeutics, Inc.

new patent Biomatrix scaffolds
The present invention provides biomatrix scaffolds, a tissue extract enriched for extracellular matrix components and bound growth factors, cytokines and hormones, and methods of making and using same.. .
The University Of North Carolina At Chapel Hill

new patent Scaffold tray and tool case
A scaffold tray and tool case for holding and storing tools upon a scaffold. The tray surface includes openings of various sizes to accommodate tools.

new patent Osteogenic regenerative scaffold matrix composition
The implantable scaffold matrix composition for osteogenic regeneration has a biodegradable polymer material selected from the group consisting of one or more of polylactic acid, polyglycolic acid, or polycaprolactone, or any combination thereof to provide a time release delivery of an osteogenic effect and further has a pharmaceutical composition selected from the group consisting of one or more of ibuprofen, non-steroidal anti-inflammatory drugs (nsaids), acetaminophen, or naproxen sodium or any combination thereof and wherein the implantable composition has a primary and a secondary time release. The primary time release being one of the polymer compositions; each time release extending occurring between 0 days and 19 days, both not being at 0 days.
Nova Southeastern University

new patent Magnesium/polymer composite-containing scaffolds to enhance tissue regeneration
The invention relates to magnesium-polymer composites, methods for their preparation and applications for their use. The composites include a combination of magnesium particles and polymer matrix.
University Of Pittsburgh-of The Commonwealth System Of Higher Education

new patent Amphiphilic degradable polymers for immobilization and sustained delivery of biomolecules
The invention provides a novel approach to controlled delivery of biomolecules (e.g., lipids and proteins) by employing novel amphiphilic polymers that are effective delivery vehicles. These unique amphiphilic polymers may be employed as controlled delivery vehicles or tissue engineering scaffolds wherein the delivery of lipophilic or amphiphilic bioactive molecules can be achieved.
University Of Massachusetts

new patent Small molecule hsp70 inhibitors
In an effort to discover therapies for treating hsp70 related diseases, a previously unidentified hydrophobic pocket was found in the c-terminal domain of dnak and of human hsp70. A novel chemical scaffold was also discovered for identifying compounds that treat diseases related to this hydrophobic pocket.
The Wistar Institute Of Anatomy And Biology

Gamified video listing application with scaffolded video production
Described are systems, media, and methods for providing high quality, gamified real estate video listings by providing an interface for creating a video listing, the video listing of a type selected from: property walkthrough, neighborhood tour, or neighborhood location, the interface comprising an interactive scaffolded video template comprising a plurality of sequenced video sections, each section defining a subject matter and a video length and, upon activation by a user, facilitating acquisition of a corresponding video clip; providing a map view interface comprising video listings; and awarding points for user activity within the application, the user activity comprising creation of video listings, the points used to allocate user promotions.. .
Roofshoot, Llc

Polypeptide libraries with a predetermined scaffold
Populations of polypeptide variants based on a common scaffold, each polypeptide in the population comprising the scaffold amino acid sequence exxxaxxeix xlpnltxxqx xafixklxdd psqssellse akklndsq (seq id no: 1) or akyakexxxaxx eixxlpnltx xqxxafixkl xddpsqssel lseakklnds q (seq id no: 2), wherein each x individually corresponds to an amino acid residue which is varied in the population are disclosed. Also populations of polynucleotides, wherein each member encodes a member of a polypeptide population are disclosed.
Affibody Ab

Gaseous storage system, methods for making and using the same

The present description relates to an adsorbent monolith, method to make the adsorbent monolith, and a gaseous storage system that includes an adsorbent monolith according to the present disclosure. In particular, the adsorbent monolith includes adsorbent, a binder, and a scaffold material..
Ingevity South Carolina, Llc

Electrospinning of cartilage and meniscus matrix polymers

Disclosed herein are methods of producing a cartilaginous implant by producing a polymer scaffold composition by electrospinning a polymer solution onto a collector in order to obtain polymer fibers; crosslinking the polymer fibers; and adding a plurality of cells to the polymer scaffold composition, wherein the plurality of cells comprises cartilaginous cells to form a cartilaginous implant.. .
Scripps Health

Injectable silk fibroin foams and uses thereof

The inventions provided herein relate to compositions, methods, delivery devices and kits for repairing or augmenting a tissue in a subject. The compositions described herein can be injectable such that they can be placed in a tissue to be treated with a minimally-invasive procedure (e.g., by injection).
Trustees Of Tufts College

Method of manufacturing scaffold for treatment of tooth extraction socket and implantation of dental implant

Provided is a technique of allowing a dental implant to be stably placed after extraction, to be accurately placed in a tooth extraction socket, and to be stably placed in the tooth extraction socket according to implantation position and angle. A method of manufacturing a scaffold for treatment of a tooth extraction socket and implantation of a dental implant includes receiving dental implantation information of dental ct data which is previously input via a terminal of a manager; manufacturing, by using a three-dimensional (3d) printer, a 3d model comprising alveolar bones and teeth, which are distinguished therebetween, based on a medical image file that is a medical image file (dicom file) of the dental ct data; performing virtual tooth-extraction by removing, from the manufactured 3d model, a region corresponding to a tooth in a tooth-extraction target area; and manufacturing, by using the 3d printer, a scaffold to be placed in an actual tooth extraction socket according to a shape of a tooth extraction socket that exists in the manufactured 3d model as a result of the virtual tooth-extraction, wherein, when the scaffold is manufactured, image data of the scaffold is amended to allow a guide hole for implanting the dental implant to be formed in the scaffold based on the dental implantation information..
The Catholic University Of Korea Industry-academic Cooperation Foundation

Medical device having extenable members

This disclosure provides design, material, manufacturing method, and use alternatives for medical devices. An example medical device includes a scaffold including a central member and a plurality of extension members extending away from the central member.
Boston Scientific Scimed, Inc.

Method for demolishing a building

A method for demolishing a building, where the building comprises a building base placed in proximity of a ground, or placed on the ground, and an opposite building top or temporary building top arranged away from the building base, as well as building floors. The equipment used in the method includes a platform adapted to be positioned against the top of the building, avoiding ground support devices which extend from the platform to the base of the building or the ground surrounding the building.
Despe S.p.a.

Compositions and methods that involve protein scaffolds that specifically bind to hepatocyte growth factor receptor

This disclosure describes a non-naturally occurring protein scaffold that specifically binds to hepatocyte growth factor receptor (met) and methods of using such protein scaffolds. Generally, the protein scaffold includes a frame and at least one loop region that specifically binds hepatocyte growth factor receptor (met).
Regents Of The University Of Minnesota

4-((2-hydroxy-3-methoxybenzyl)amino)benzenesulfonamide derivatives as potent and selective inhibitors of 12-lipoxygenase

Human lipoxygenases (loxs) are a family of iron-containing enzymes involved in catalyzing the oxidation of polyunsaturated fatty acids to provide the corresponding bioactive hydroxyeicosatetraenoic acid (hete) metabolites. These eicosanoid signaling molecules are involved in a number of physiologic responses such as platelet aggregation, inflammation, and cell proliferation.
Thomas Jefferson University

Method for producing carbonates

In an embodiment, a method of producing a carbonate comprises reacting carbon monoxide and chlorine in a phosgene reactor in the presence of a catalyst to produce a first product comprising phosgene; wherein carbon tetrachloride is present in the first product in an amount of 0 to 10 ppm by volume based on the total volume of phosgene; and reacting a monohydroxy compound with the phosgene to produce the carbonate; wherein the phosgene reactor comprises a tube, a shell, and a space located between the tube and the shell; wherein the tube comprises one or more of a mini-tube section and a second tube section; a first concentric tube concentrically located in the shell; a twisted tube; an internal scaffold; and an external scaffold.. .
Sabic Global Technologies B.v.

Plasticizers for a biodegradable scaffolding and methods of forming same

Methods of making polymeric devices, such as stents, with one or more modifications such as addition of plasticizers, to improve processing, and the devices made by these methods.. .
Abbott Cardiovascular Systems Inc.

Scaffold loading and delivery systems

This disclosure describes, inter alia, materials, devices, kits and methods that may be used for loading scaffolds into delivery devices and delivery of scaffolds into the body of a patient, including delivery of scaffolds to the sinuses for the treatment of chronic sinusitis, among other purposes.. .

Osteoconductive and osteoinductive implant for augmentation, stabilization, or defect reconstruction

Aspects of the present invention provide implants for augmentation, stabilization, or defect reconstruction of bone tissue, comprising a scaffold portion structured to provide shape to the implant, the scaffold portion comprising one or more of the following: one or more polylactic acid isomer; one or more polyglycolic acid isomer; and/or allogenic bone material, or similar compound.. .
University Of South Florida

Liver infection

The invention relates to a method for studying an infection process in liver tissue in vitro, the method comprising: seeding hepatocyte cells onto a scaffold in a bioreactor in order to form a liver tissue model;delivering an infectious agent to the liver tissue model, or providing the liver tissue model pre-infected with an infectious agent; and monitoring the infection process; and a method for producing an infectious agent.. .
Cn Bio Innovations Limited

Process of making scaffold with interface to promote coating adhesion

Methods of fabricating a stent are disclosed including forming a primer layer on a surface of the scaffold including a first polylactide polymer. The primer layer includes a second polylactide polymer and is free of a therapeutic agent.
Abbott Cardiovascular Systems Inc.

Implantable scaffolds for treatment of sinusitis

This disclosure describes, inter alia, materials, devices, kits and methods that may be used to treat chronic sinusitis.. .

Pegylated fibrinogen precursor molecule

The present invention relates to biodegradable scaffolds composed of a naturally-occurring protein backbone cross-linked by a synthetic polymer. Specifically, the present invention provides pegylated-fibrinogen scaffold and methods of generating and using same for treating disorders requiring tissue regeneration..
Regentis Biomaterials Ltd.

Dimeric scaffold peptides comprising hiv-1 gp120 and gp41 epitopes

The present invention relates to novel peptides and methods for inducing an immune response in a subject against an antigen and for treatment, diagnosis and prognosis of infections or autoimmune diseases including infections with hcv, hiv, cmv and flu. The invention further relates to methods for identifying and providing peptides useful for the treatment and diagnosis..
Bionor Immuno As

Drug-eluting coatings on poly(dl-lactide)-based scaffolds

Stents including a poly(d,l-lactide)(pdlla)-based scaffold and pdlla based therapeutic layer are disclosed. The pdlla based scaffold may be amorphous and may include a primer layer.
Abbott Cardiovascular Systems Inc.

Engineered intervertebral disc (ivd) for degenerated disc disease

The present invention provides a process by which both non-tissue engineered and tissue engineered cartilaginous-like structures can be fabricated. The process of the present invention provides a method to produce electrospun nanofiber-anchored np gels.
University Of Central Oklahoma

Implantable scaffolds for treatment of sinusitis

This disclosure describes, inter alia, materials, devices, kits and methods that may be used to treat chronic sinusitis.. .

Novel peptides and combination of peptides for use in immunotherapy and methods for generating scaffolds for the use against pancreatic cancer and other cancers

The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer.
Immatics Biotechnologies Gmbh

Scaffold for tissue engineering and fabricating the same

A scaffold for tissue engineering includes a frame structure including one of poly-d-lactic acid and poly-l-lactic acid, and a coating layer formed on a surface of the frame structure and including a lactic acid-glycolic acid copolymer.. .
Gc Corporation

Method of fabricating scaffold for tissue engineering

A method of fabricating a scaffold for tissue engineering that includes a frame structure including one of poly-d-lactic acid and poly-l-lactic acid and a coating layer formed on a surface of the frame structure and including a lactic acid-glycolic acid copolymer. The method includes mixing a first granular porous substance including one of poly-d-lactic acid and poly-l-lactic acid with a second granular porous substance including the lactic acid-glycolic acid copolymer to prepare a mixture, and pressurizing and heating the mixture in a mold.
Gc Corporation

Implant introducer with helical trigger wire

A delivery device for deploying an expandable, endoluminal prosthesis within a body vessel is disclosed. The delivery device may include one or more stent graft retention scaffolds having a plurality of arches, each arch encompassing an aperture forming a helical path and a trigger wire passing through at least two of the apertures following the helical path, wherein at least a portion of the stent graft is retained in a compressed configuration on the delivery device by the retention scaffold and trigger wire..
Cook Medical Technologies Llc

3d printer

A method of reproducing a biological object includes 3d-imaging the object and generating a mold using a 3d printer; obtaining cells from a donor site on the object; preparing a live cell suspension using the cells from the donor site; forming a scaffold in the mold with collagen and seeding the scaffold with live cells, growing the cells in the mold and curing the collagen; and surgically implanting the object into a living subject, where the cells continue to live in the living subject.. .

Tenocyte containing bioscaffolds and treatment using the same

The present invention relates to methods for preparing bioscaffolds useful in the repair of tears. More specifically, the invention relates to a method of treating rotator cuff tear in a mammalian subject in need thereof comprising the steps of: (i) selectively expanding tenocytes in vitro in culture medium comprising insulin or a functional derivative and a glucocorticoid or a glucocorticoid-like molecule to produce a culture of expanded tenocytes; (ii) seeding a bioscaffold with said expanded tenocytes to produce a tenocyte seeded bioscaffold; and (iii) implanting said tenocyte seeded bioscaffold proximal to the rotator cuff tear.
Orthocell Pty Ltd

Biomimetic hydrogel scaffolds and related methods

Provided herein are methods of making a biomimetic hydrogel scaffold comprising a polycation and a polyanion. Also provided are anisotropic biomimetic hydrogel scaffold compositions suitable for use in tissue growth, including bone, muscle, and nerve growth an optionally comprising a carbon allotrope such as graphene.
University Of Pittsburgh - Of The Commonwealth System Of Higher Education

Bioactive modification of poly(vinyl alcohol) with surface topography and biochemical cues for vascular graft

Modifications of the biomaterial poly(vinyl alcohol) with surface topographical cues, attachment factors for its improved performance, and/or sustained release of vascular endothelial biochemical cue for application as a vascular graft scaffold is described. Furthermore, novel fabrication methods to pattern the poly(vinyl alcohol) hydrogel in planar film or tubular form with the topographies in the lumen are disclosed..
Institut National De La Sante Et De La Recherche Medicale (inserm)

Materials for treating and preventing mucosa related disease

Provided is a hyaluronic acid (ha) composition for use in treating or preventing mucosa related disorders or diseases including a mixture of has having different average molecular weights and different rheological, isolation, tissue scaffold and degradation properties. The resulting formulation demonstrates an optimal balance between adhesion, tissue scaffold and treating time on the treatment and prevention of mucosa related disorders or diseases including conjunctivitis, otitis, allergic rhinitis, gingivitis, oral ulcer, bronchitis, gastroesophageal reflux disease (gerd), esophagitis, gastritis, enteritis, peptic ulcer, inflammatory bowel disease (ibd), irritable bowel syndrome (ibs), urethritis, cystitis and vaginitis..
Aihol Corporation

Stents and catheters having improved stent deployment

An implant delivery system and method comprises an implant, for example, a stent, and a delivery catheter. The stent has a scaffold with a coating or a shell that retains the scaffold in a collapsed configuration.
Covidien Lp

Scaffolds having a radiopaque marker and methods for attaching a marker to a scaffold

A scaffold includes a radiopaque marker connected to a strut. The marker is retained within the strut by a head at one or both ends.
Abbott Cardiovascular Systems Inc.

Methods and devices for preparing and implanting tissue scaffolds

Methods and devices are provided for preparing and implanting tissue scaffolds. Various embodiments of scribing tools are provided that are configured to mark one or more predetermined shapes around a defect site in tissue.
Depuy Mitek, Llc

Low diffuse scatter, anechoic chamber absorber

An electromagnetic chamber absorber provided improved absorption across a wideband and both lower diffuse and specular scatter and a method for constructing the same. An exemplary device can compromise a periodic arrangement of disconnected electromagnetically lossy elements where the periodicity of the lattice is adjusted to suppress all or most grating lobe scattering.

Wound treatment apparatus and method

An apparatus and method for aspirating, irrigating and/or cleansing wounds is provided. The apparatus and method include one or more of the following: simultaneous aspiration and irrigation of the wound, supplying of thermal energy to fluid circulated through the wound; supplying physiologically active agents to the wound; a biodegradable scaffold in contact with the wound bed; and application of stress or flow stress to the wound bed..
Smith & Nephew Plc

Scaffold for tissue growth and repair

Provided is an electroactive structure and method for growing isolated differentiable cells comprising a three dimensional matrix of fibers formed of a biocompatible synthetic piezoelectric polymeric material, wherein the matrix of fibers is seeded with the isolated differentiable cells and forms a supporting scaffold for growing the isolated differentiable cells, and wherein the matrix of fibers stimulates differentiation of the isolated differentiable cells into a mature cell phenotype on the structure.. .
New Jersey Institute Of Technology

Nano-engineered coatings for anode active materials, cathode active materials, and solid-state electrolytes and methods of making batteries containing nano-engineered coatings

The present disclosure relates to a nano-engineered coating for cathode active materials, anode active materials, and solid state electrolyte materials for reducing corrosion and enhancing cycle life of a battery, and processes for applying the disclosed coating. Also disclosed is a solid state battery including a solid electrolyte layer having a solid electrolyte particle coated by a protective coating with a thickness of 100 nm or less.
Pneumaticoat Technologies Llc

Scaffold-free 3d porous electrode and making a scaffold-free 3d porous electrode

A scaffold-free 3d porous electrode comprises a network of interconnected pores, where each pore is surrounded by a multilayer film including a first layer of electrochemically active material, one or more monolayers of graphene on the first layer of electrochemically active material, and a second layer of electrochemically active material on the one or more monolayers of graphene. A method of making a scaffold-free 3d porous electrode includes depositing one or more monolayers of graphene onto a porous scaffold to form a graphene coating on the porous scaffold, and depositing a first layer of an electrochemically active material onto the graphene coating.
The Board Of Trustees Of The University Of Illinois

Scaffold topics:
  • Nucleotide
  • Recombinant
  • Polynucleotide
  • Amino Acid
  • Biodegradable
  • Encapsulation
  • Surfactant
  • Enhancement
  • Monoclonal Antibody
  • Polypeptide
  • Immunogenic
  • Amino Acid Sequence
  • Monoclonal
  • Interleukin 2
  • Immune Disease

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    This listing is a sample listing of patent applications related to Scaffold for is only meant as a recent sample of applications filed, not a comprehensive history. There may be associated servicemarks and trademarks related to these patents. Please check with patent attorney if you need further assistance or plan to use for business purposes. This patent data is also published to the public by the USPTO and available for free on their website. Note that there may be alternative spellings for Scaffold with additional patents listed. Browse our RSS directory or Search for other possible listings.


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