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Scaffold patents



      
           
This page is updated frequently with new Scaffold-related patent applications. Subscribe to the Scaffold RSS feed to automatically get the update: related Scaffold RSS feeds. RSS updates for this page: Scaffold RSS RSS


Ear scaffold

Methods of treatment directed to neointimal proliferation generated by endothelial shear stress patterns from…

Modified scaffolds for peripheral applications

Date/App# patent app List of recent Scaffold-related patents
08/14/14
20140228970
 Tissue engineering device and construction of vascularized dermis patent thumbnailTissue engineering device and construction of vascularized dermis
An inkjet printing method, system, and computer-usable tangible storage device to print cells and biomaterials for three-dimensional cellular scaffolds and engineered skin grafts are disclosed. The process simultaneously deposits living cells, nutrients, growth factors, therapeutic drugs along with biomaterial scaffolds at the right time and location.
08/14/14
20140228953
 Ear scaffold patent thumbnailEar scaffold
A scaffold for reshaping the cartilaginous portion of an ear. The scaffold is formed of shape memory material and in the form of a horseshoe shape, or is formed from a thermoplastic pliable material..
08/14/14
20140228932
 Methods of treatment directed to neointimal proliferation generated by endothelial shear stress patterns from drug-eluting bioresorbable vascular scaffold implantation patent thumbnailMethods of treatment directed to neointimal proliferation generated by endothelial shear stress patterns from drug-eluting bioresorbable vascular scaffold implantation
Treatments of coronary heart disease including the effect of endothelial shear stress (ess) on neointimal formation following a bioresorbable vascular scaffold implantation are disclosed.. .
08/14/14
20140228930
 Modified scaffolds for peripheral applications patent thumbnailModified scaffolds for peripheral applications
Stent scaffolds that include a polymeric structure or structures bonded to the scaffold and extending along their length are disclosed. The polymeric structure extends across some or all of the gaps in struts along the length of the scaffold.
08/14/14
20140228893
 Bone plate positioning scaffold patent thumbnailBone plate positioning scaffold
A device to maintain temporary engagement with a bone plate and a bone, the device comprising a first biased appendage positioned opposite a second biased appendage, the first and second biased appendages including an arcuate vertical profile that partially defines an interior region; a platform concurrently coupled to the first and second biased appendages, the platform also partially defining the interior region, the platform including a through hole open to the interior region; a first tab extending from at least one of the first biased appendage, the second biased appendage, and the platform, the first tab extending into the interior region and adapted to engage a bone plate; a first arcuate flange mounted to a distal portion of the platform; and a second arcuate flange mounted to a proximal portion of the platform.. .
08/14/14
20140227783
 Methods and apparatus for building complex 3d scaffolds and biomimetic scaffolds built therefrom patent thumbnailMethods and apparatus for building complex 3d scaffolds and biomimetic scaffolds built therefrom
A novel method for building complex three-dimensional scaffolds for biomimetic applications such as in vitro organ growth, using a gelatin/sugar/water gel, ultraviolet radiation, and heat or enzyme is described. The method produces gelatin-sugar hydrogels demonstrating greater thermal stability, mechanical strength, and resistance to enzymatic degradation.
08/14/14
20140227782
 Thermosensitive, bioactive biopolymer and associated method of cell harvesting patent thumbnailThermosensitive, bioactive biopolymer and associated method of cell harvesting
The present invention relates to a biopolymer and a cell-harvesting scaffold comprising same, as well as the associated cell-harvesting method that allows said harvesting to be performed in a simple and effective manner by reducing the culture temperature. The present invention also relates to a method for synthesising said biopolymer..
08/14/14
20140227364
 Methods of manufacturing bioactive gels from extracellular matrix material patent thumbnailMethods of manufacturing bioactive gels from extracellular matrix material
The present invention is directed to methods of manufacturing bioactive gels from ecm material, i.e., gels which retain bioactivity, and can serve as scaffolds for preclinical and clinical tissue engineering and regenerative medicine approaches to tissue reconstruction. The manufacturing methods take advantage of a new recognition that bioactive gels from ecm material can be created by digesting particularized ecm material in an alkaline environment and neutralizing to provide bioactive gels..
08/14/14
20140227362
 Methods of manufacturing bioactive gels from extracellular matrix material patent thumbnailMethods of manufacturing bioactive gels from extracellular matrix material
The present invention is directed to methods of manufacturing bioactive gels from ecm material, i.e., gels which retain bioactivity, and can serve as scaffolds for preclinical and clinical tissue engineering and regenerative medicine approaches to tissue reconstruction. The manufacturing methods take advantage of a new recognition that bioactive gels from ecm material can be created by digesting particularized ecm material in an alkaline environment and neutralizing to provide bioactive gels..
08/14/14
20140227339
 Regenerative tissue grafts and methods of making same patent thumbnailRegenerative tissue grafts and methods of making same
A graft containing a scaffold that includes a matrix in which are positioned mesenchymal progenitor cells (mpcs) has the capacity to substantially improve wound healing, including wounds resulting from injury to nerve, bone and vascular tissue. Mpcs can be harvested from debrided muscle tissue following orthopaedic trauma.
08/14/14
20140227336
Tissue engineering methods and compositions
Cells are employed in conjunction with unique biologically-compatible scaffold structures to generate differentiated tissues and structures, both in vitro and in vivo. The presently disclosed subject matter further relates to methods of forming and using improved tissue engineered scaffolds that can be used as substrates to facilitate the growth and differentiation of cells..
08/07/14
20140222152
Implantable intervertebral disc devices and uses thereof
Provided herein are implantable intervertebral disc devices, and methods of making the same. For example, an implantable intervertebral disc device comprises an engineered annulus fibrosus (af) scaffold that can mimic its native-like cross alignment of pores/channels within the af region, and can be served as a scaffolding material for cell and matrix alignment.
08/07/14
20140222144
Anti-paravalvular leakage component for a transcatheter valve prosthesis
A transcatheter valve prosthesis includes an expandable tubular stent, a prosthetic valve within the stent, and an anti-paravalvular leakage component coupled to and encircling the tubular stent. The anti-paravalvular leakage component includes a radially-compressible annular scaffold, which is a sinusoidal patterned ring of self-expanding material, and an impermeable membrane extending over the annular scaffold.
08/07/14
20140222135
Prosthetic heart valves, scaffolding structures, and systems and methods for implantation of same
Prosthetic valves and their component parts are described, as are prosthetic valve delivery devices and methods for their use. The prosthetic valves are particularly adapted for use in percutaneous aortic valve replacement procedures.
08/07/14
20140221615
Porous scaffold material, and method for producing same
Provided are a scaffold material that functions as a scaffold material for two weeks or more in vivo and causes substantially no foreign-body reaction, and a method for producing the scaffold material. Specifically, a porous scaffold material comprising collagen fibers is provided..
08/07/14
20140221569
Decorated macromolecular scaffolds
The present invention relates to a method for preparing decorated macromolecular scaffolds. The method of the invention is useful for the generation of bioactive nanoparticles for use in clinical applications.
08/07/14
20140220496
Method of forming photoresist structure
A method for forming a photoresist structure is provided the method includes the step of forming a photoresist layer on a substrate, the step of exposing a portion of the photoresist layer to form an exposed portion of the photoresist layer, and the step of removing the photoresist layer except the exposed portion with a solvent, so as to form the photoresist structure, wherein the photoresist layer has a polymer having a structure represented by formula (i). The method of the present invention can generate a photoresist with an even thickness on devices with complex geometries or three-dimensional substrates.
08/07/14
20140219963
Extracellular matrix-derived gels and related methods
Provided are methods for preparing gelled, solubilized extracellular matrix (ecm) compositions useful as cell growth scaffolds. Also provided are compositions prepared according to the methods as well as uses for the compositions.
08/07/14
20140219962
Porous chitosan scaffolds and related methods
Porous chitosan scaffold having high mechanical strength, methods for making the porous chitosan scaffold, and method for using the porous chitosan scaffold.. .
08/07/14
20140216637
Methods of making medical devices
Scaffold-supported metal or pseudometallic film covers suitable for use as medical devices are disclosed together with methods of fabricating the devices. Methods for making the medical devices consist of either providing or forming a scaffold, then depositing a metallic or pseudometallic film cover onto the scaffold in such a manner as to form an integral, substantially monolithic junction between the deposited cover material and the scaffold..
07/31/14
20140214173
Dynamic bioactive nanofiber scaffolding
A resorbable bone graft scaffold material, including a plurality of overlapping and interlocking fibers defining a scaffold structure, plurality of pores distributed throughout the scaffold, and a plurality of glass microspheres distributed throughout the pores. The fibers are characterized by fiber diameters ranging from about 5 nanometers to about 100 micrometers, and the fibers are a bioactive, resorbable material.
07/31/14
20140213765
Albumin tissue scaffold
A tissue scaffold that made of albumin having continuous solid network and void are disclosed. Methods for preparing albumin tissue scaffolds from animal albumins are also disclosed..
07/31/14
20140212716
Monolithic three-dimensional electrochemical energy storage system on aerogel or nanotube scaffold
A monolithic three-dimensional electrochemical energy storage system is provided on an aerogel or nanotube scaffold. An anode, separator, cathode, and cathodic current collector are deposited on the aerogel or nanotube scaffold..
07/31/14
20140212664
Inorganic nanowires
Provided in one embodiment is a method of forming an inorganic nanowire, comprising: providing an elongated organic scaffold; providing a plurality of inorganic nanoparticles attached to the organic scaffold along a length of the organic scaffold; and fusing the nanoparticles attached to the organic scaffold to form an inorganic nanowire.. .
07/31/14
20140212469
Surface functional bioactive glass scaffold for bone regeneration
A bioactive glass scaffold treated to modify the surface of the bioactive glass scaffold for regenerating new bone tissue is disclosed. In some embodiments, the bioactive glass scaffold may include pores in a grid-like structure to promote the ingrowth of bone tissue, and the modified surface layer may include a hydroxyapatite-like surface.
07/31/14
20140212356
Methods and compositions for treating luminal inflammatory disease
Compositions, articles, and methods for treating and imaging vulnerable plaque and other inflamed regions in a patient rely on delivery of a conversion electron emitting source (cees) to a body location. The cees may be delivered by coupling to a substance which preferentially binds to vulnerable plaque or other inflammatory marker.
07/31/14
20140208491
Flame resistant yarns and fabrics including partially aromatic polyamide fiber and other flame resistant fibers
Disclosed are technical fibers and yams made with partially aromatic polyamides and a fiber having vapor phase action such as an fr cellulosic fiber. Fabrics made from such fibers and yarns demonstrate superior flame retardancy over traditional flame retardant nylon 6,6 fabrics.
07/24/14
20140207250
Tissue scaffold
A process of forming a tissue scaffold is described, the process comprising electrospinning polymer fibers from a spinneret onto a tissue scaffold template. In embodiments, the fibers are plasma-treated between the spinneret and the template.
07/24/14
20140207248
Hierarchical multiscale fibrous scaffold via 3-d electrostatic deposition prototyping and conventional electrospinning
A hierarchical multiscale fibrous scaffold comprises multiple patterned layers of microfibers with one or more layers of nanofibers interleaved therebetween. In a method for making such scaffolds, electrodeposition or near-field electrospinning is used to deposit patterned layers of microfibers in a stack.
07/24/14
20140207179
Method and apparatus for placing a catheter within a vasculature
A catheter for insertion into vasculature of a patient to a target area in the vasculature includes a hollow inner shaft, a non-occluding self-expandable scaffold coupled to the distal end of the inner shaft and disposed at the distal end of the inner shaft, and a hollow outer shaft. The outer shaft is slidable over the inner shaft and scaffold such that the scaffold is in a non-expanded state when the outer shaft is around the scaffold.
07/24/14
20140206967
Loading data generator for use with a therapeutic scaffold and methods for use therewith
A loading data generator can be used with a scaffold for delivery within a patient. The loading data generator includes a driving circuit electrically coupled to drive an impedance of the scaffold.
07/24/14
20140206958
Wireless degradation data generator for use with a therapeutic scaffold and methods for use therewith
A degradation data generator is used with a scaffold for delivery within a patient. The degradation data generator includes a driving circuit electrically coupled to drive an impedance of the scaffold.
07/24/14
20140206839
Cross linked hyaluronic acid-silk and uses thereof
The present specification provides for methods for purifying fibroins, purified fibroins, methods of conjugating biological and synthetic molecules to fibroins, fibroins conjugated to such molecules, methods of making fibroin hydrogels, fibroin hydrogels and fibroin hydrogel formulations useful for a variety of medical uses, including, without limitation uses as bulking agents, tissue space fillers, templates for tissue reconstruction or regeneration, cell culture scaffolds for tissue engineering and for disease models, surface coating to improve medical device function, or drug delivery devices.. .
07/24/14
20140206556
Systems and methods for identifying replikin scaffolds and uses of said replikin scaffolds
The present invention provides a new class of peptides related to rapid replication and high human mortality, and their use in diagnosing, preventing and treating disease including vaccines and therapeutics for emerging viral diseases and methods of identifying the new class of peptides and related structures.. .
07/24/14
20140205636
Fibrin sealant compositions with chemical crosslinking
The invention relates to tissue adhesives or sealants, more specifically to fibrinogen based sealants reinforced with particulate material and chemically cross-linked. More particularly, the present invention is directed to tissue sealant, adhesive, hemostat, or scaffolding material containing thrombin, fibrinogen, a biocompatible particulate material having amine functionality, and a biocompatible polymer containing aldehyde groups.
07/24/14
20140203214
Flexible, semiconducting nanocomposite materials based on nanocrystalline cellulose and polyaniline
A new approach is conceived for the development of organic polymeric conducting materials synthesized from nanocomposites of nanocrystalline cellulose (ncc) and polyaniline (pani). The process involves oxidative-radical polymerization of aniline in the presence of ncc using either in situ or emulsion polymerization.
07/24/14
20140202795

A pipe-support system including a pipe-support frame structure having plural, substantially horizontal, pipe-support levels supported by columns including a distribution of side columns uniformly spaced along at least one side of the frame structure, and featuring selectively graduated, support-level-indifferent, lateral-connectivity access for quickly available, removeable, outrigger gravity attachment to the frame's side columns, through gravity catch and hook structures, of modular, outrigger, lateral, worker-platform scaffolding either as individual scaffolding units, or as assemblies of plural, individual units, all such units deriving vertical support through outrigger connections made to the frame structure.. .
07/24/14
20140201973
Methods for uniform crimping and deployment of a polymer scaffold
A medical device-includes a scaffold crimped to a catheter having an expansion balloon. The scaffold is crimped to the balloon by a process that includes one or more balloon pressurization steps.
07/17/14
20140200678
Biomaterials with microsphere gradients and core and shell microspheres
Methods can prepare tissue engineering scaffolds that include a plurality of biocompatible core/shell microspheres linked together to form a three-dimensional matrix. The matrix can include a plurality of pores for growing cells.
07/17/14
20140200597
Biodegradable apparatus and method for closure of trocar defects
A biodegradable device for providing scaffolding for a trocar defect to promote healing. The device consists of an upper and lower scaffold, offset by a connector.
07/17/14
20140199766
Transgenic system for reversibly immortalizing mammalian quiescent cells
A transgene for endowing human quiescent cells from primary cultures with exogenously inducible telomere length homeostasis and cell cycle traverse is described. The transgene includes at least three promoter sequences; a g1-specific rna interference sequence which is operably linked downstream of a first promoter sequence; a telomere length maintenance gene sequence which is operably linked downstream to a second promoter sequence; a scaffold/matrix attachment region (s/mar) element positioned downstream in frame with said telomere length maintenance gene sequence and an exogenously-inducible transcriptional regulation system.
07/17/14
20140199276
Inkjet printing of tissues and cells
Provided herein is an apparatus for printing cells which includes an electrospinning device and an inkjet printing device operatively associated therewith. Methods of making a biodegradable scaffold having cells seeded therein are also provided.
07/10/14
20140194987
Silk covered breast implant
The present specification provides for methods for purifying fibroins, purified fibroins, methods of conjugating biological and synthetic molecules to fibroins, fibroins conjugated to such molecules, methods of making fibroin hydrogels, fibroin hydrogels and fibroin hydrogel formulations useful for a variety of medical uses, including, without limitation uses as bulking agents, tissue space fillers, templates for tissue reconstruction or regeneration, cell culture scaffolds for tissue engineering and for disease models, surface coating to improve medical device function, or drug delivery devices.. .
07/10/14
20140194602
Metamaterial optical elements self-assembled on protein scaffolds
A genetically modified cowpea mosaic virus (cpmv) protein capsid serves as a scaffold for metal nanoparticles, preferably gold nanospheres, of 15 nm to 35 nm, creating plasmonic nanoclusters. The self-assembled nanoclusters gave rise to a 10-fold surface-averaged enhancement of the local electromagnetic field.
07/10/14
20140193488
In situ antigen-generating cancer vaccine
The invention provides compositions and methods for utilizing scaffolds in cancer vaccines.. .
07/10/14
20140193468
Methods for preparation of neo-cartilage constructs
The invention generally relates to systems (i.e. Constructs) for repairing cartilage and methods for preparing the same that introduce a bioactive agent into a culture medium, suspension, scaffold, solution incorporated into the pores of the scaffold, or combinations thereof.
07/10/14
20140189994
Post-crimping inspection of scaffolds mounted on scaffold delivery systems
A system for mounting a scaffold on a balloon catheter includes two positioning and alignment stations, which are used to prepare a scaffold and catheter for crimping using the same crimping head. The system is configured for automated assembly of the scaffold and catheter prior to crimping and performing post-crimping inspection for the crimped scaffold and prior to placing a restraining sheath over the crimped scaffold..
07/03/14
20140188242
Demineralized cancellous bone scaffolds
The present invention provides a cancellous bone scaffold to use in the replacement or repair of connective tissue such as ligaments and tendons. The cancellous bone scaffold has a fully demineralized segment with at least one adjacent mineralized end segment..
07/03/14
20140188227
Fibrous scaffold for use in soft tissue engineering
The present invention relates to a fibrous scaffold for use as a substrate in soft tissue applications, in particular for preparing annulus fibrosus (af) tissue. In aspects, the present invention also relates to an engineered biological material comprising af tissue; constructs comprising one or more engineered biological materials; methods for producing the biological materials and constructs; and methods of using the biological materials and constructs..
07/03/14
20140187488
Methods for maintaining pegylation of polypeptides
Described herein are methods for maintaining pegylation and inhibiting depegylation of polypeptides, such as fibronectin-based scaffold proteins, during storage.. .
07/03/14
20140186952
Scaffold-free tissue constructs
A tissue construct comprising includes a self-assembled, scaffold-free, high-density cell aggregate. The cell aggregate includes a plurality of cells and a plurality of biocompatible and degradable nanoparticles and/or microparticles that are incorporated within the cell aggregate.
07/03/14
20140186455
Tissue repair system
An implant for promoting accelerated wound healing. The implant comprises a non-flocculating fiber material, admixed with a settable fluid.
07/03/14
20140186413
Preparation method of core-shell structured fibrous scaffolds
The present invention relates to a preparation method for core-shell structured fibrous scaffolds, and more specifically to preparing a core part composition and a shell part composition that each have different constitutions by adding calcium phosphate cement and a protein, drug of combination thereof to alginate solution, and then inserting the above core part composition and shell part composition to internal and external nozzle of concentric nozzle respectively to inject into calcium ion aqueous solution and thereby hardening them, thus preparing core-shell structured rapidly setting alg/α-tcp scaffolds capable of controllably releasing a protein or drug.. .
07/03/14
20140186320
Methods and compositions for the treatment, prevention, and alleviation of bone and cartilage diseases or injuries and hair loss
The present invention provides pharmaceutical compositions, and methods of preparation and use for the treatment, prevention or alleviation of bone and cartilage diseases or injuries and hair loss. The present invention discloses a method and a pharmaceutical composition comprising mesenchymal stem cells, platelets, activating factors and scaffolding materials for the treatment, prevention, or alleviation of bone diseases, bone injuries or hair loss, and a method and a pharmaceutical composition further comprising dexamethasone for the treatment, prevention, or alleviation of cartilage diseases or injuries..
07/03/14
20140186304
Compositions for regenerating defective or absent myocardium
Compositions of the invention for regenerating defective or absent myocardium comprise an emulsified or injectable extracellular matrix composition. The composition may also include an extracellular matrix scaffold component of any formulation, and further include added cells, proteins, or other components to optimize the regenerative process and restore cardiac function..


Popular terms: [SEARCH]

Scaffold topics: Nucleotide, Recombinant, Polynucleotide, Amino Acid, Biodegradable, Encapsulation, Surfactant, Enhancement, Monoclonal Antibody, Polypeptide, Immunogenic, Amino Acid Sequence, Monoclonal, Interleukin 2, Immune Disease

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This listing is a sample listing of patent applications related to Scaffold for is only meant as a recent sample of applications filed, not a comprehensive history. There may be associated servicemarks and trademarks related to these patents. Please check with patent attorney if you need further assistance or plan to use for business purposes. This patent data is also published to the public by the USPTO and available for free on their website. Note that there may be alternative spellings for Scaffold with additional patents listed. Browse our RSS directory or Search for other possible listings.
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