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This page is updated frequently with new Scaffold-related patent applications. Subscribe to the Scaffold RSS feed to automatically get the update: related Scaffold RSS feeds. RSS updates for this page: Scaffold RSS RSS


Bioresorbable scaffold for neurologic drug delivery

Bioresorbable scaffold for neurologic drug delivery

Bioabsorbable polymeric medical device

Bioabsorbable polymeric medical device

Bioabsorbable polymeric medical device

Device and method for orthopedic fracture fixation

Date/App# patent app List of recent Scaffold-related patents
11/13/14
20140336755
 Tubular scaffold for fabrication of heart valves patent thumbnailTubular scaffold for fabrication of heart valves
A tubular braided mesh scaffold for fabrication of heart valves is described. The tubular braided scaffold can be formed of a shape memory metal, such as nitinol, and pinched or pressed to form a leaflet shape.
11/13/14
20140336750
 Bioresorbable scaffold for neurologic drug delivery patent thumbnailBioresorbable scaffold for neurologic drug delivery
Bioresorbable scaffolds and methods of treatment with such scaffolds for neurologic disorders including parkinson's disease, huntington's disease, alzheimer's disease, and brain neoplasms are disclosed. The bioresorbable scaffold includes a bioresorbable body and an active agent or drug associated with the body for treating or ameliorating the neurological disorder.
11/13/14
20140336748
 Bioabsorbable polymeric medical device patent thumbnailBioabsorbable polymeric medical device
In embodiments there is described a cardiovascular tube-shaped lockable and expandable bioabsorbable scaffold having a low immunogenicity manufactured from a crystallizable bioabsorbable polymer composition or blend.. .
11/13/14
20140336710
 Device and method for orthopedic fracture fixation patent thumbnailDevice and method for orthopedic fracture fixation
The present invention relates invention relates to devices and methods for the fixation and stabilization of orthopedic fractures and more specifically to stabilization of compression fractures of spinal vertebrae. The systems comprise cannulated orthopedic screws and mechanical expandable implants introducible through the lumen of such screws.
11/13/14
20140336557
 Biopolymer multi-layer multi-functional medical dressing and method of making same patent thumbnailBiopolymer multi-layer multi-functional medical dressing and method of making same
The technology described herein applies to medical dressings designed to heal wounds in the area of advanced wound care, inclusive of negative pressure wound therapy (npwt), and describes novel wound healing absorbent scaffolds and dressing based on natural and naturally-derived material and fibers, preferentially poly (lactic) acid fibers and alginate materials.. .
11/13/14
20140336242
 Micro-rna scaffolds and non-naturally occurring micro-rnas patent thumbnailMicro-rna scaffolds and non-naturally occurring micro-rnas
The present disclosure provides a non-naturally occurring mirna having a stem-loop structure comprising a scaffold derived from a first endogenous mirna (e.g., mir-196a-2 or mir-204), a mature strand derived from a second endogenous mirna, and a star strand sequence that is at least partially complementary to the mature strand sequence. The present disclosure also provides a non-naturally occurring mirna having a stem-loop structure comprising a scaffold derived from an endogenous mirna (e.g., mir-196a-2 or mir-204), a mature strand designed to be at least partially complementary to a target rna, and a star strand sequence that is at least partially complementary to the mature strand sequence.
11/13/14
20140335144
 Tissue scaffolds derived from forestomach extracellular matrix patent thumbnailTissue scaffolds derived from forestomach extracellular matrix
The present invention pertains to the development of extracellular matrix (ecm) scaffolds derived from the forestomach of a ruminant. Such scaffolds are useful in many clinical and therapeutic applications, including wound repair, tissue regeneration, and breast reconstruction.
11/13/14
20140335141
 Layered manufacturing utilizing foam as a support and multifunctional material for the creation of parts and for tissue engineering patent thumbnailLayered manufacturing utilizing foam as a support and multifunctional material for the creation of parts and for tissue engineering
One aspect of the invention provides a solid freeform fabrication method of creating a three-dimensional article built at least in part from scaffolding layers. The method includes: providing a scaffolding material; providing a supporting material in a shape of a foamy layer; and contacting the scaffolding material with the foamy layer to form at least one scaffolding layer and thereby creating the three dimensional article.
11/13/14
20140335050
 Methods, compositions, and kits for the treatment of cancer patent thumbnailMethods, compositions, and kits for the treatment of cancer
The invention features methods, compositions, and kits for the administration of an hsp90 inhibitor, obaa, flunarizine, aphidicolin, damnacanthal, dantrolene, or an analog thereof, alone, or in combination with, e.g., a taa, an antigen-binding scaffold (e.g., an antibody, a soluble t cell receptor, or a chimeric receptor) specific for a taa, a cell (e.g., a white blood cell that targets a cancer cell), and/or an ifn-β receptor agonist or an ifn-γ receptor agonist, for the treatment of cancer.. .
11/06/14
20140330392
 Scaffolds for tissues and uses thereof patent thumbnailScaffolds for tissues and uses thereof
The present invention provides tissue scaffolds, methods of generating such scaffolds, and methods of use of such scaffolds to generate aligned and functional tissues for use in methods including regenerative medicine, wound repair, and transplantation.. .
11/06/14
20140330363
Polymer scaffolds having a low crossing profile
A medical device includes a polymer scaffold crimped to a catheter having an expansion balloon. The scaffold, after being deployed by the balloon, provides a crush recovery of about 90% after the diameter of the scaffold has been pinched or crushed by 50%.
11/06/14
20140330361
Segmented scaffold designs
Segmented scaffolds composed of disconnected scaffold segments with overlapping end rings are disclosed. Scaffolds with at least one discontinuous link are also disclosed..
11/06/14
20140330360
Segmented scaffold designs
Segmented scaffolds composed of disconnected scaffold segments with overlapping end rings are disclosed. Scaffolds with at least one discontinuous link are also disclosed..
11/06/14
20140330359
Methods and apparatus for stent delivery and deployment
For scaffolds delivered and deployed intravascularly, one or several configurations may be employed for creating a smoother transition from balloon-to-scaffold. For instance, one or more spacers may be positioned in proximity to the scaffold.
11/06/14
20140330310
Patent foramen ovale (pfo) closure device with radial and circumferential support
The present invention provides a device for occluding an anatomical aperture, such as a septal defect or patent foramen ovale (pfo). The occluder includes two sides connected by an intermediate joint.
11/06/14
20140329992
Porous tissue scaffolds
A method for forming a porous tissue material.. .
11/06/14
20140329323
Three-dimensional nanostructured hybrid scaffold and manufacture thereof
A method of making a three-dimensional biocompatible scaffold capable of supporting cell activities such as growth and differentiation, the method includes providing a supporting grid that forms an open network and provides mechanical support of a second biocompatible material. The second biocompatible material has interconnected cavities that allow nutrients, metabolites and soluble factors to diffuse throughout the scaffold.
11/06/14
20140329225
Target detection with nanopore
Provided are methods for detecting a target molecule or particle suspected to be present in a sample, comprising (a) contacting the sample with (i) a fusion molecule comprising a ligand capable of binding to the target molecule or particle and a binding domain, and (ii) a polymer scaffold comprising at least one binding motif to which the binding domain is capable of binding, under conditions that allow the target molecule or particle to bind to the ligand and the binding domain to bind to the binding motif; (b) loading the polymer into a device comprising a pore that separates an interior space of the device into two volumes, and configuring the device to pass the polymer through the pore from one volume to the other volume, wherein the device further comprises a sensor adjacent to the pore configured to identify objects passing through the pore; and (c) determining, with the sensor, whether the fusion molecule or particle bound to the binding motif is bound to the target molecule or particle, thereby detecting the presence of the target molecule or particle in the sample.. .
11/06/14
20140328916
3-dimensional cardiac fibroblast derived extracellular matrix
A bioscaffold made from an isolated cardiac fibroblast-derived 3-dimensional extracellular matrix (ecm) is disclosed. The bioscaffold can be used as an epicardial patch for the delivery of therapeutic cells into myocardial tissue.
11/06/14
20140328888
Swellable fiber and microfiber forming polyether-esters and applications thereof
Biomedical and tissue engineering devices, such as surgical sutures and microporous scaffolds, respectively, which undergo swelling and increase in dimensions when placed in aqueous environments such as living tissues, are produced by the melt-spinning or electrostatic spinning into strong monofilament and multifilament yarns or microfibrous fabrics, respectively. Such devices are formed from especially high molecular weight crystalline polyether-esters having a minimum inherent viscosity of 0.8 dl/g and heat of fusion of at least 5 j/g, wherein the polyether-esters are made by grafting to a polyester component a polyether glycol component having a minimum molecular weight of about 11 kda with at least one cyclic monomer..
11/06/14
20140328853
Anti-adrenomedullin (adm) antibody or anti-adm antibody fragment or anti-adm non-ig scaffold for prevention or reduction of organ dysfunction or organ failure in a patient having a chronic or acute disease or acute condition
Subject matter of the present invention is an anti-adrenomedullin (adm) antibody or an anti-adrenomedullin antibody fragment or an anti-adm non-ig scaffold for use in therapy of a chronical or acute disease or acute condition of a patient for prevention or reduction of organ dysfunction or organ failure. In a preferred embodiment subject matter of the invention is an anti-adm antibody or an anti-adrenomedullin antibody fragment or anti-adm non-ig scaffold for use in therapy of a chronical or acute disease or acute condition of a patient for prevention or reduction of kidney dysfunction or kidney failure or liver dysfunction or liver failure..
11/06/14
20140328806
Energetic three-dimensional artificial cardiac patch and uses thereof
In some embodiments, the present disclosure provides a method for fabricating a three-dimensional artificial cardiac patch construct. In some embodiments, such method includes the steps of coating a substrate with an organic polymer; allowing the organic polymer coating to air dry; mounting anchors on the organic polymer coating; and sterilizing the organic polymer coating and the anchors.
11/06/14
20140328789
Ph-responsive cell scaffold and method of using same
A ph-responsive cell scaffold for growing a cell culture is disclosed. The cell scaffold has pores in which biological cells may be disposed.
11/06/14
20140328619
Non-complex cable to panel connector with inseparable parts
A scaffolding connector. A first part includes a first plate, a first rod portion extending downwardly therefrom then upwardly to define a cradle, and a second rod portion extending upwardly therefrom then downwardly into close proximity therewith.
11/06/14
20140326661
Liquid filtration media containing melt-blown fibers
A filter and filter media configured and arranged for placement in a fuel stream is disclosed. The filter and filter media allow for filtering of liquid fuels, such as diesel fuel.
11/06/14
20140326649
Novel nanocomposites and their application as monolith columns
Novel materials for chromatographic separations, processes for their preparation, and separation devices containing the chromatographic materials. In particular, hybrid inorganic/organic monolith materials comprising a polymerized scaffolding nanocomposite (psn), wherein the nanocomposite contains a scaffolding functionally capable of chemically interacting with a surface of a second material are described.
11/06/14
20140325825
Method of assembling an offset working platform on a scaffold structure using a foldable knee-out scaffold frame member
A method of assembling a offset working surface on a scaffold. The method uses a scaffold knee out member having a first and second scaffold members that are pivotally connected.
10/30/14
20140323548
Novel amino alcohol cationic lipids for oligonucleotide delivery
The instant invention provides for novel cationic lipids that can be used in combination with other lipid components such as cholesterol and peg-lipids to form lipid nanoparticles with oligonucleotides. It is an object of the instant invention to provide a cationic lipid scaffold that is more efficacious than traditional cationic lipids.
10/30/14
20140322785
Continuous flow bioreactor for magnetically stabilized three-dimensional tissue culture
The invention provides methods for rapid, continuous generation of cells and cell products using magnetically stabilized three-dimensional tissue culture. The invention also pertains to a continuous flow self-regulating closed system bioreactor system for magnetically stabilized three-dimensional tissue culture.
10/30/14
20140322225
Anti-adrenomedullin (adm) antibody or anti-adm antibody fragment or anti-adm non-ig scaffold for use in therapy of an acute disease or acute condition of a patient for stabilizing the circulation
In a preferred embodiment anti-adm antibody or an anti-adrenomedullin antibody fragment or an anti-adm non-ig scaffold according to the present invention reduces the vasopressor requirement, e.g. Catecholamine requirement of said patient.
10/30/14
20140321908
Standard and ledger of a scaffolding system, and method for erecting the same
A standard (10) of a scaffolding system (1), comprising an elongate tubular wall (12), having a central longitudinal axis (ls), and at least one supporting projection (14) that protrudes radially outwardly from said tubular wall (12). When the standard (10) is in a vertical orientation, the supporting projection (14), seen in a tangential direction (ts) relative to the longitudinal axis (ls), forms an annular supporting surface (16) that encircles the tubular wall (12) and that defines alternating elevations (18) and depressions (20).
10/30/14
20140319724
Bioabsorbable scaffold with particles providing delayed acceleration of degradation
Methods of controlling the degradation profile of a biodegradable stent scaffolding are disclosed. A bioabsorbable scaffold having a plurality of particles incorporated into the scaffolding that accelerate the absorption of the scaffolding after an induction time during degradation is disclosed..
10/30/14
20140318895
Adjustable length scaffolding and method therefor
A scaffolding system for an attic area has a plurality of board members. An attachment device is sued for securing a first board member to an adjoining board member, wherein the attachment device comprises a pair of removable attachment devices formed on a pair of opposing sides of each board member..
10/23/14
20140316109
Activated collagen scaffold materials and their special fused active restoration factors
Provided are activated collagen scaffold materials as well as their special fused active restoration factors useful for promoting tissue repair, such as bone damage repair or nerve injury repair. The special fused active restoration factors are fusion proteins comprising a collagen-binding domain (cbd) at n-/c-terminus of cytokines, wherein the collagen-binding domain is a polypeptide consisting of 7-27 amino acid residues with a conservative sequence shown in seq id no:12 at n-terminus.
10/23/14
20140315308
Glucomannan scaffolding for three-dimensional tissue culture and engineering
The present invention provides a neutralized glucomannan scaffold capable of promoting cell growth and suitable for three-dimensional tissue culture and engineering. The present invention also provides methods for making and degrading the neutralized glucomannan scaffold.
10/23/14
20140315295
Polymer microfilters, devices comprising the same, methods of manufacturing the same, and uses thereof
A microfilter having a hydrophilic surface and suited for size-based capture and analysis of cells, such as circulating cancer cells, from whole blood and other human fluids is disclosed. The filter material is photo-definable, allowing the formation of precision pores by uv lithography.
10/23/14
20140315253
Activated collagen scaffold materials and their special fused active restoration factors
Provided are activated collagen scaffold materials as well as their special fused active restoration factors useful for promoting tissue repair, such as bone damage repair or nerve injury repair. The special fused active restoration factors are fusion proteins comprising a collagen-binding domain (cbd) at n-/c-terminus of cytokines, wherein the collagen-binding domain is a polypeptide consisting of 7-27 amino acid residues with a conservative sequence shown in seq id no:4 at n-terminus.
10/23/14
20140315235
Coated fiber scaffold for three dimensional cell culture of neural cells
The invention relates to a biocompatible scaffold for three dimensional cultivation of cells, said scaffold comprise one or more fibers randomly oriented to form a scaffold with open spaces for cultured cells. The one or more fibers are also coated with a bio-active coating and have a diameter of 100-3000 nm..
10/23/14
20140315093
Use and fabrication of microscaffolds and nanoscaffolds
A scaffold includes struts that intersect at nodes. In some instances, a cross section of the cores has at least one dimension less than 100 microns.
10/23/14
20140314948
Method of fabricating a three-dimensional (3d) porous electrode architecture for a microbattery
A method of fabricating a 3d porous electrode architecture comprises forming a microbattery template that includes (a) a lattice structure comprising a first lattice portion separated from a second lattice portion on a substrate, and (b) a solid structure on the substrate including a separating portion between the first and second lattice portions. Interstices of the first lattice portion are infiltrated with a first conductive material and interstices of the second lattice portion are infiltrated with a second conductive material.
10/23/14
20140314824
Porous scaffold for tissue engineering and preparation method thereof
A porous artificial transplant material to replace autogenous bone with excellent biocompatibility, cytocompatibility and biodegradability is provided. More specifically, a porous scaffold for tissue engineering including chitosan/hydroxyapatite-amylopectin (chitosan/hap-ap) and a preparation method thereof are provided.
10/23/14
20140314817
Injectable silk fibroin foams and uses thereof
The inventions provided herein relate to compositions, methods, delivery devices and kits for repairing or augmenting a tissue in a subject. The compositions described herein can be injectable such that they can be placed in a tissue to be treated with a minimally-invasive procedure (e.g., by injection).
10/23/14
20140314775
Anti-adrenomedullin (adm) antibody or anti-adm antibody fragment of anti-adm non-ig scaffold for regulating the fluid balance in a patient having a chronic or acute disease
Patients having a chronic or acute disease or acute condition, especially patients at the icu (intensive care unit) suffer from fluid imbalance. The present invention provides a medicament for regulating the fluid balance and/or improving the fluid balance of such patients.
10/23/14
20140311820
Three-dimensional air-adsorbing structure
A three-dimensional air-adsorbing structure for use in a volume in which there is a time-varying acoustic field. The structure has a three-dimensional, unitary, skeletal, porous scaffold having scaffold openings distributed within its volume, where the scaffold openings make up at least about 50% of the volume of the scaffold, air-adsorbing material particles, and a hydrophobic binder that couples air-adsorbing material particles to each other to form agglomerates and couples particles and agglomerates to the scaffold.
10/16/14
20140309739
Joint bioscaffolds
Provided herein are compositions and medical devices, and in particular, biodegradable scaffolds capable of repairing and replacing cartilagenous meniscuses. Also provided herein are methods of using scaffolds for treating degenerative tissue disorders.
10/16/14
20140309738
Membrane-scaffold composites for tissue engineering applications
Collagen-glycosaminoglycan membrane shell scaffold core composites for connective tissue engineering that avoids aspects of the typical tradeoff between mechanical properties (i.e. Modulus, failure strength) and bioactivity (i.e., permeability and porosity) for porous tissue engineering scaffolds.
10/16/14
20140309726
Biodegradable vascular grafts
Disclosed herein are biodegradable scaffolds for in situ tissue engineering. In some examples, biodegradable vascular grafts and methods of fabricating and uses of such are disclosed.
10/16/14
20140309722
Stent apparatus
An object is to surely hold a stent formed of a biodegradable polymer and shape memorized to an expanded size having a diameter larger than an inner diameter of a vessel on a balloon in contracted state. A stent apparatus comprises a stent formed of a biodegradable polymer material using polylactic acid having a shape memory property as a tubular shape and shape memorized to a size capable of scaffolding a vessel from the inside when implanted in the vessel; and a stent holding member formed of a biodegradable polymer material for covering the outer surface of the stent to hold the stent in a contracted state that is smaller in diameter than the shape memorized size, wherein a stent detecting member is attached to the stent and a part of the stent holding member is fixed to the stent detecting member..
10/16/14
20140309163
Fibronectin based scaffold domain proteins that bind to myostatin
The present invention relates to fibronectin-based scaffold domain proteins that bind to myostatin. The invention also relates to the use of these proteins in therapeutic applications to treat muscular dystrophy, cachexia, sarcopenia, osteoarthritis, osteoporosis, diabetes, obesity, copd, chronic kidney disease, heart failure, myocardial infarction, and fibrosis.
10/16/14
20140308507
Systems and methods for capture and sequestration of gases and compositions derived therefrom
A composition is produced by a hydrothermal liquid phase sintering process, and the process includes providing a porous matrix, the porous matrix having a shape, and allowing a component of the porous matrix to undergo a reaction with an infiltrating medium to form a first product, the infiltrating medium including a greenhouse gas, a remainder of the porous matrix acting as a scaffold for facilitating the formation of the first product. The composition includes the first product and the reminder of the porous matrix.
10/16/14
20140308362
Injectable silk fibroin particles and uses thereof
The inventions provided herein relate to compositions, methods, delivery devices and kits for repairing or augmenting a tissue in a subject. The compositions described herein are injectable such that they can be placed in a tissue to be treated with a minimally-invasive procedure (e.g., by injection) and/or be molded flexibly into a tissue void of any shape and/or size.
10/16/14
20140308303
Method for selecting a candidate drug compound
The disclosure relates to the field of candidate drug testing and drug development. A method is provided for providing a compound composed of at least one molecule attached via at least two linkages to a molecular scaffold, the method comprising providing a scaffold comprising at least a first and a second reactive group; providing at least one molecule capable of reacting with the at least first and second reactive group; contacting the scaffold with at least one molecule to form at least two linkages between the scaffold and the at least one molecule in a coupling reaction, wherein the formation of a linkage accelerates the formation of a consecutive linkage, preferably wherein the coupling reaction is performed in solution, more preferably in an aqueous solution.
10/16/14
20140305864
Inorganic fibrous membrane and a method of fabricating thereof
A method of fabricating an inorganic fibrous membrane, the method comprising the steps of: grafting sulfonated graphene oxide onto a scaffold of inorganic nanofibers to form a suspension of heterojunctions of the sulfonated graphene oxide and the scaffold; filtering the suspension through a support to obtain heterojunctions on the support; drying the heterojunctions on the support; and removing the support to obtain the inorganic fibrous membrane.. .
10/16/14
20140305737
Mobile scaffolding units with extendible gantry platform and methods of using same
Mobile scaffolding units include a vehicle for movement across ground surface, a stationary platform rigidly fixed to the vehicle at a predetermined immovable height above the ground surface, and a gantry platform operatively connected to the stationary platform for movements between a retracted position where the gantry platform is nested adjacent to the stationary platform, and an extended position wherein the gantry platform extends laterally outwardly from one or another lateral side of the stationary platform to provide an operator on the gantry platform an extended horizontal reach laterally of the vehicle. The mobile scaffolding units allow an operator to work at elevated heights and with lateral reach in one area of a work zone (e.g., to trim roadside vegetation) and then move to another area of the work zone without requiring an operator to dismount from the gantry platform..
10/16/14
20140305070
Constructing method for concrete cylinder of construction steel bar of high-rise steel structure
A constructing method for a concrete cylinder of a construction steel bar of a high-rise steel structure adopts a constructing method of supporting inside and climbing outside. The outside of the cylinder adopts hydraulic mutual-climbing adhesive lifting scaffold creeping formwork system (100), and also has an outside wallboard mechanical formwork erection function and an outer frame protection function.
10/09/14
20140303123
Synthesizing functionalized dendrimers within biological settings
The present invention relates to compositions (e.g., dendrimer scaffolds) capable of click chemistry for use in synthesis of functionalized dendrimers within biological settings, and methods of use of the same.. .
10/09/14
20140302594
Cell culture assay
The present invention relates to a cell culture assay. The present invention comprises: a substrate; a scaffold channel which is formed along the centre inside the substrate, and of which at least one is disposed continuously, and inside which a scaffold flows; and a microfluidic channel or channels which is/are respectively formed on one side or on both sides of the scaffold channel, and inside which cells flow, and, here, a leak-preventing part for preventing the scaffold from leaking into the microfluidic channel(s) is formed in at least one of the ceiling surface and the floor surface of a boundary part of the scaffold channel and the microfluidic channel(s)..
10/09/14
20140302277
Panel and use of such a panel as a scaffolding board or a building panel
The present invention relates to a panel comprising two parallel skin plates made of wood or a wood material, between which ribs extend for stiffening the panel, wherein the ribs are at least substantially made of wood or a wood material. The present invention further relates to the use of such a panel as a scaffolding board or a construction element and to scaffolding provided with such panels..
10/09/14
20140302227
Methods of coating a construct with methylated collagen
A double-structured tissue implant and a method for preparation and use thereof for implantation into tissue defects. The double-structured tissue implant comprising a primary scaffold and a secondary scaffold consisting of a soluble collagen solution in combination with a non-ionic surfactant generated and positioned within the primary scaffold.
10/09/14
20140302144
Multi-layered injectable self-assembling peptide scaffold hydrogels for long-term sustained release of human antibodies
The invention relates to a pharmaceutical formulation for sustained delivery of a therapeutic agent, preferably a protein, polypeptide, an antibody or an antibody fragment, comprising one or more gel forming peptides wherein the formulation exhibits sustained delivery for at least two weeks, three weeks, four weeks, five weeks, six weeks, seven weeks, eight weeks, nine weeks, ten weeks, eleven weeks, twelve weeks or more. In one embodiment, the invention relates to a formulation comprising self-assembling peptides that undergo sol-gel transition in the presence of an electrolyte solution such as biological fluids and salts.
10/09/14
20140302117
Tissue products including a temperature change composition containing phase change components within a non-interfering molecular scaffold
Wiping products, such as facial tissues, contain a temperature change composition that can provide a cooling sensation when contacted with the skin of a user. The temperature change composition includes a phase change material and a non-interfering molecular scaffold.
10/09/14
20140302111
Compositions and methods for dental tissue regeneration
Provided is a method for regenerating dental tissue, which can include contacting a scaffold containing wnt3a and bmp-7, and optionally vegf, bfgf, or ngf, with a dental tissue so as to promote odontoblastic differentiation of a progenitor cell, promote progenitor cell migration into the dental tissue, or regenerate the dental tissue. Also provided is a composition for regeneration of dental tissue, which can include a scaffold and wnt3a and bmp-7, and optionally vegf, bfgf, or ngf..
10/09/14
20140302110
Magnetic field-controlled movable bio-scaffold and constructing method thereof
Disclosed are a magnetic field-controlled movable bio-scaffold and a method for constructing the same. The bio-scaffold is highly biocompatible and can readily move to a target site under the control of an external magnetic field..


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Scaffold topics: Nucleotide, Recombinant, Polynucleotide, Amino Acid, Biodegradable, Encapsulation, Surfactant, Enhancement, Monoclonal Antibody, Polypeptide, Immunogenic, Amino Acid Sequence, Monoclonal, Interleukin 2, Immune Disease

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