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Scaffold patents



      
           
This page is updated frequently with new Scaffold-related patent applications. Subscribe to the Scaffold RSS feed to automatically get the update: related Scaffold RSS feeds. RSS updates for this page: Scaffold RSS RSS


Panel and use of such a panel as a scaffolding board or a building panel

Panel and use of such a panel as a scaffolding board or a building panel

Panel and use of such a panel as a scaffolding board or a building panel

Methods of coating a construct with methylated collagen

Date/App# patent app List of recent Scaffold-related patents
10/09/14
20140303123
 Synthesizing functionalized dendrimers within biological settings patent thumbnailSynthesizing functionalized dendrimers within biological settings
The present invention relates to compositions (e.g., dendrimer scaffolds) capable of click chemistry for use in synthesis of functionalized dendrimers within biological settings, and methods of use of the same.. .
10/09/14
20140302594
 Cell culture assay patent thumbnailCell culture assay
The present invention relates to a cell culture assay. The present invention comprises: a substrate; a scaffold channel which is formed along the centre inside the substrate, and of which at least one is disposed continuously, and inside which a scaffold flows; and a microfluidic channel or channels which is/are respectively formed on one side or on both sides of the scaffold channel, and inside which cells flow, and, here, a leak-preventing part for preventing the scaffold from leaking into the microfluidic channel(s) is formed in at least one of the ceiling surface and the floor surface of a boundary part of the scaffold channel and the microfluidic channel(s)..
10/09/14
20140302277
 Panel and use of such a panel as a scaffolding board or a building panel patent thumbnailPanel and use of such a panel as a scaffolding board or a building panel
The present invention relates to a panel comprising two parallel skin plates made of wood or a wood material, between which ribs extend for stiffening the panel, wherein the ribs are at least substantially made of wood or a wood material. The present invention further relates to the use of such a panel as a scaffolding board or a construction element and to scaffolding provided with such panels..
10/09/14
20140302227
 Methods of coating a construct with methylated collagen patent thumbnailMethods of coating a construct with methylated collagen
A double-structured tissue implant and a method for preparation and use thereof for implantation into tissue defects. The double-structured tissue implant comprising a primary scaffold and a secondary scaffold consisting of a soluble collagen solution in combination with a non-ionic surfactant generated and positioned within the primary scaffold.
10/09/14
20140302144
 Multi-layered injectable self-assembling peptide scaffold hydrogels for long-term sustained release of human antibodies patent thumbnailMulti-layered injectable self-assembling peptide scaffold hydrogels for long-term sustained release of human antibodies
The invention relates to a pharmaceutical formulation for sustained delivery of a therapeutic agent, preferably a protein, polypeptide, an antibody or an antibody fragment, comprising one or more gel forming peptides wherein the formulation exhibits sustained delivery for at least two weeks, three weeks, four weeks, five weeks, six weeks, seven weeks, eight weeks, nine weeks, ten weeks, eleven weeks, twelve weeks or more. In one embodiment, the invention relates to a formulation comprising self-assembling peptides that undergo sol-gel transition in the presence of an electrolyte solution such as biological fluids and salts.
10/09/14
20140302117
 Tissue products including a temperature change composition containing phase change components within a non-interfering molecular scaffold patent thumbnailTissue products including a temperature change composition containing phase change components within a non-interfering molecular scaffold
Wiping products, such as facial tissues, contain a temperature change composition that can provide a cooling sensation when contacted with the skin of a user. The temperature change composition includes a phase change material and a non-interfering molecular scaffold.
10/09/14
20140302111
 Compositions and methods for dental tissue regeneration patent thumbnailCompositions and methods for dental tissue regeneration
Provided is a method for regenerating dental tissue, which can include contacting a scaffold containing wnt3a and bmp-7, and optionally vegf, bfgf, or ngf, with a dental tissue so as to promote odontoblastic differentiation of a progenitor cell, promote progenitor cell migration into the dental tissue, or regenerate the dental tissue. Also provided is a composition for regeneration of dental tissue, which can include a scaffold and wnt3a and bmp-7, and optionally vegf, bfgf, or ngf..
10/09/14
20140302110
 Magnetic field-controlled movable bio-scaffold and constructing method thereof patent thumbnailMagnetic field-controlled movable bio-scaffold and constructing method thereof
Disclosed are a magnetic field-controlled movable bio-scaffold and a method for constructing the same. The bio-scaffold is highly biocompatible and can readily move to a target site under the control of an external magnetic field..
10/09/14
20140299413
 Dual latching horizontal scaffold member patent thumbnailDual latching horizontal scaffold member
One embodiment of the invention is a horizontal scaffold member having a primary end connector and a secondary end connector. Each end connector is configured to couple to a cup on a vertical scaffold member.
10/02/14
20140296996
 Membrane-type artificial scaffold and method for fabricating same patent thumbnailMembrane-type artificial scaffold and method for fabricating same
Provided herein are a membrane-type artificial scaffold for guided bone regeneration (gbr) and a method for fabricating the same. The membrane-type artificial scaffold according to the present invention comprises: a first layer made of at least one fiber layer arranged in parallel with each other with a first spacing therebetween such that the fiber layer contacts a bone tissue in vivo; and a second layer stacked on the first layer and made of at least one fiber layer arranged parallel to each other with a second spacing therebetween such that the fiber layer contacts a soft tissue in vivo.
10/02/14
20140296965
Monolithic medical devices, methods of making and using the same
The monolithic device comprises a plurality of scaffolding members and a mesh patterned members webbed between the scaffolding members; the mesh patterned member webbed between the scaffolding members surround a lumen and generally expands from a contracted state to an expanded state; and mesh patterned members including a plurality of openings traversing the thickness of the mesh patterned member, and the mesh patterned members including a surface on which a pattern of openings is formed.. .
10/02/14
20140296886
Device and method for deploying and attaching an implant to a biological tissue
This present invention generally relates to devices and methods for repairing an aperture in a biological tissue. In certain embodiments, the invention provides a system for closing an aperture in a biological tissue including a handle, an elongate shaft connected to the handle, and a deployment scaffold connected to the shaft, in which the scaffold is configured to releasably retain a surgical implant and the scaffold is configured to deploy and attach the surgical implant to the biological tissue..
10/02/14
20140296798
Occlusion device for closing anatomical defects
An occlusion device for closing an anatomical defect in tissue comprising a conduit connecting an opening on a first tissue and an opening on a second tissue is provided. The occlusion device comprises a scaffold comprising a) a proximal support structure comprising at least two arms; b) a distal support structure comprising at least two arms, wherein the arms are adapted to provide anchorage for the device in the tissue; and c) a waist portion adapted for extending through the opening on the first tissue and connecting the proximal support structure with the distal support structure, wherein the scaffold consists essentially of a biodegradable polymer, wherein the proximal support structure and the distal support structure comprise or consist of polycaprolactone (pcl), poly-(d,l-lactide-co-caprolactone) (plc), or a mixture thereof.
10/02/14
20140296623
Preparation of regenerative tissue scaffolds
Devices and methods for treating or repairing a tissue or organ defect or injury are provided. The devices can include tissue scaffolds produced from acellular tissue matrices and polymers, which have a stable three-dimensional shape and elicit a limited immunologic or inflammatory response..
10/02/14
20140296487
Modified human plasma polypeptide or fc scaffolds and their uses
Modified human plasma polypeptides or fc and uses thereof are provided.. .
10/02/14
20140296478
Method for selecting a candidate drug compound
The disclosure relates to the field of candidate drug testing and drug development. Described are methods for providing a compound composed of at least one molecule attached via at least two linkages to a molecular scaffold, the method comprising providing a scaffold comprising at least a first and a second reactive group; providing at least one molecule able to react with the at least first and second reactive group; and contacting the scaffold with at least one molecule to form at least two linkages between the scaffold and the molecule in a coupling reaction, wherein the formation of a linkage accelerates the formation of a consecutive linkage.
10/02/14
20140296358
Implantable embolic scaffolds that promote healing
Implant devices and structures that reduce inflammation and promote healing of the area of implant. Specifically, the use of shape memory open cell biocompatible polymer foams for implants that assist in and promote healing and especially in filling and sealing aneurisms..
10/02/14
20140294913
Biodegradable bone fillers, membranes and scaffolds containing composite particles
This invention is related to bone fillers, hard tissue supporting films and three dimensional scaffolds that contains composite particle of inorganic compound/water soluble polymer (such as β-tcp/gelatin), that can lead to bone regeneration and release an antibacterial or bioactive agent at the defect area. The bone regenerative hard tissue supporting films and scaffolds were obtained by addition of antibacterial or bioactive agent loaded composite particles into biodegrable polymer (such as pcl) matrix..
10/02/14
20140294823
Heterodimeric proteins
The present invention describes novel immunoglobulin compositions that co-engage at least two antigens, e.g. A first and second antigen, or, as outlined herein, three or four antigens can be bound, in some of the scaffold formats described herein.
10/02/14
20140294786
Alimentary protein-based scaffolds (aps) for wound healing, regenerative medicine and drug discovery
The invention provides engineered biomaterials derived from plant products. The engineered biomaterials are useful for biomedical applications.
10/02/14
20140294783
Implantable scaffolds and methods of use
Inventive concepts relate general to the field of implantable three-dimensional scaffolds. More particularly, methods of preparing and using implantable nanofibrous tissue scaffolds are described.
10/02/14
20140294765
Lsr antibodies, and uses thereof for treatment of cancer
This invention relates to antibodies and antigen binding fragments and conjugates containing same, and/or alternative scaffolds, specific for lsr molecules, which are suitable drugs for immunotherapy and treatment of specific cancer.. .
10/02/14
20140294733
Multifunctional small molecules
The present invention relates to dendrimer synthesis. Specifically, the present invention relates to dendrimer compositions (e.g., scaffolds) capable of copper-free click conjugation for use in the synthesis of functionalized dendrimers, and methods of use of the same..
10/02/14
20140294701
Surface-functionalized mesoporous carbon materials
A functionalized mesoporous carbon composition comprising a mesoporous carbon scaffold having mesopores in which polyvinyl polymer grafts are covalently attached, wherein said mesopores have a size of at least 2 nm and up to 50 nm. Also described is a method for producing the functionalized mesoporous composition, wherein a reaction medium comprising a precursor mesoporous carbon, vinyl monomer, initiator, and solvent is subjected to sonication of sufficient power to result in grafting and polymerization of the vinyl monomer into mesopores of the precursor mesoporous carbon.
09/25/14
20140288661
Bone tissue engineering by ex vivo stem cells ongrowth into three-dimensional trabecular metal
Adult autologous stem cells cultured on a porous, three-dimensional tissue scaffold-implant for bone regeneration by the use of a hyaluronan and/or dexamethasone to accelerate bone healing alone or in combination with recombinant growth factors or transfected osteogenic genes. The scaffold-implant may be machined into a custom-shaped three-dimensional cell culture system for support of cell growth, reservoir for peptides, recombinant growth factors, cytokines and antineoplastic drugs in the presence of a hyaluronan and/or dexamethasone alone or in combination with growth factors or transfected osteogenic genes, to be assembled ex vivo in a tissue incubator for implantation into bone tissue..
09/25/14
20140288534
Tissue harvesting
The present disclosure relates to a tissue collection apparatus including a housing defining an inlet and an outlet and a tissue scaffold suitable for disposal within the housing, the tissue scaffold configured to be loaded with the tissue under the application of an aspiration force applied through the tissue collection apparatus.. .
09/25/14
20140288323
Cyclopropenimine catalyst compositions and processes
The present invention provides, inter alia, a cyclopropenimine brønsted base catalyst and a cyclopropenimine scaffold for use as a brønsted base catalyst. This cyclopropenimine has the structure (100).
09/25/14
20140287507
Incorporation of plant virus particles and polymers as 2d and 3d scaffolds to manipulate cellular behaviors
Methods are generally disclosed for attaching a cell binding motif to a carboxy end of a coat protein of a tobacco mosaic virus particle to form a modified-tmv particle; and attaching a cell to the cell binding motif of the modified-tmv particle.. .
09/25/14
20140287018
Nanoparticle-based scaffolds and implants, methods for making the same, and applications thereof
Implant-associated bacterial infections are one of the most serious complications in orthopedic surgery. Treatment of these infections often requires multiple operations, device removal, long-term systemic antibiotics, and extended rehabilitation, and is frequently ineffective, leading to worse clinical outcomes and increased financial costs.
09/25/14
20140287017
Solid forms for tissue repair
This invention provides aragonite- and calcite-based scaffolds for the repair, regeneration, enhancement of formation or a combination thereof of cartilage and/or bone, which scaffolds comprise at least two phases, wherein each phase differs in terms of its chemical content, or structure, kits comprising the same, processes for producing solid aragonite or calcite scaffolds and methods of use thereof.. .
09/25/14
20140287006
Degradation-stabilised, biocompatible collagen matrices
The present invention relates to degradation-stabilised, biocompatible collagen matrices which are distinguished in particular by the fact that they contain soluble collagen and peptide constituents, to processes for the preparation of such collagen matrices, which processes include in particular chemical crosslinking with an epoxy-functional crosslinking agent, and to the use of the collagen matrices according to the invention as a cosmetic or pharmaceutical agent, in particular for topical use, and as a wound treatment agent, as an implant or as a haemostatic agent in humans or animals, and as a scaffold for cell population in the biotechnology, basic research and tissue engineering field.. .
09/25/14
20140286865
Synthetic diblock copolypeptide hydrogels for use in the central nervous system
This invention relates, e.g., to a composition suitable for administration to the central nervous system (cns), comprising a block copolypeptide hydrogel, which comprises a biologically active material that is mixed with the hydrogel or that is attached to the polypeptide chain of the hydrogel, wherein the composition is suitable for administration to the cns. Also disclosed are methods of making and using compositions of the invention as depots or as scaffolds for cell migration, and pharmaceutical compositions and kits for implementing methods of the invention..
09/18/14
20140278853
Extrinsic incentivized scaffolding in computer games via advertising responsive to intrinsic game events
In an embodiment, a data processing method comprises receiving, by a mobile app, incentive data comprising one or more app event types, wherein each app event type is associated with an incentive frequency value and a reward type; detecting an occurrence of an app event of the mobile app, wherein the app event is associated with a particular app event type of the one or more app event types; determining, based on the incentive frequency value for the particular app event type, whether to generate a scaffolding event comprising displaying an advertisement and providing a reward of the reward type associated with the particular app event type; displaying the advertisement and providing the reward; wherein the method is performed by one or more computing devices.. .
09/18/14
20140277578
Biodegradable composite scaffold for repairing defects in load-bearing bones
A tissue scaffold for repair and regeneration of bone hard tissue or muscle, skin, or organ soft tissue, including load-bearing bone tissue, the scaffold comprising a core of biocompatible, biodegradable inorganic glass fibers; and a biocompatible, biodegradable, flexible polymer film surrounding the core and adhered to the core.. .
09/18/14
20140277576
Randomly uniform three dimensional tissue scaffold of absorbable and non-absorbable materials
An implantable structure, method for making the structure and method for using the structure, where the structure includes a combination of non-absorbable and absorbable components, and the implantable structure has a randomly uniform array of materials. The resulting implantable structure provides improved tissue ingrowth and flexibility after implantation and after absorption of the absorbable materials..
09/18/14
20140277575
Randomly uniform three dimensional tissue scaffold of absorbable and non-absorbable materials
An implantable structure, method for making the structure and method for using the structure, where the structure includes a combination of non-absorbable and absorbable components, and the implantable structure has a randomly uniform array of materials. The resulting implantable structure provides improved tissue ingrowth and flexibility after implantation and after absorption of the absorbable materials..
09/18/14
20140277573
Esophageal stent
Implantable device embodiments, such as stents, and particularly esophageal stents, formed of a scaffolding structure are disclosed. The scaffolding structure is formed of one or more strand elements arranged in a braided pattern.
09/18/14
20140277461
Porous tissue ingrowth structure
A three-dimensional scaffold for a medical implant includes a plurality of layers bonded to each other. Each layer has a top surface and a bottom surface and a plurality of pores extending from the top surface to the bottom surface.
09/18/14
20140277447
Scaffold for spring ligament repair
A construct is disclosed that may be used to repair or replace a natural ligament. The construct may be formed of materials for biocompatibility and/or resorbtion.
09/18/14
20140277401
Bioabsorbable biomedical implants
A bioabsorbable biomedical implant is disclosed. The implant includes a tubular scaffold comprising a plurality of interconnected polymer struts.
09/18/14
20140277384
Medical device with selective rigidity
A device for obtaining selective rigidity with respect to a patient is provided. The device includes a scaffold that is arranged to be flexible when in a first relaxed configuration, wherein the scaffold is configured to become substantially more rigid when a suction force is applied thereto.
09/18/14
20140277372
Polymer scaffolds having enhanced axial fatigue properties
A medical device includes a polymer scaffold crimped to a catheter having an expansion balloon. The scaffold has a morphology resulting from a biaxially expanded tube arranged to provide a more balanced, or less anisotropic axial and radial mechanical properties.
09/18/14
20140277350
Implant introducer with helical trigger wire
A delivery device for deploying an expandable, endoluminal prosthesis within a body vessel is disclosed. The delivery device may include one or more stent graft retention scaffolds having a plurality of arches, each arch encompassing an aperture forming a helical path and a trigger wire passing through at least two of the apertures following the helical path, wherein at least a portion of the stent graft is retained in a compressed configuration on the delivery device by the retention scaffold and trigger wire..
09/18/14
20140277331
Reducing recoil in peripherally-implanted scaffolds
A peripherally implanted polymer scaffold having a high degree of recoil is worked to reduce recoil in the scaffold when initially deployed at a target lesion in the body. The scaffold is plastically deformed from a crimped state to an expanded state by a balloon catheter.
09/18/14
20140277008
Method and apparatus for centering a microcatheter within a vasculature
The invention is directed to methods and apparatus for centering a microcatheter within a vasculature. In one aspect, the methods and apparatus can be used to support centering and to facilitate a guidewire to cross through a chronic total occlusion.
09/18/14
20140276251
Systems for providing fluid flow to tissues
Provided is an apparatus that includes a scaffold with a gel or liquid composition deposed on at least a portion of a luminal surface, the gel or liquid composition adapted to include microbubbles. Also provided is a system that includes a source of reduced pressure, the above scaffold, a manifold adjacent the scaffold, and a conduit for providing fluid communication between the manifold and the source of reduced pressure.
09/18/14
20140274759
Modification of polypeptides
The invention provides a method for conjugating a peptide displayed on a genetic display system to a molecular scaffold performed on an ion exchange resin.. .
09/18/14
20140273223
Micro-device for culturing cells, method for manufacturing same, and method for culturing cells using the micro-device for culturing cells
Disclosed is micro-device for culturing cells comprising: a plurality of fluid paths through which fluid moves; and at least one inlet port for injecting fluid to the fluid paths, said fluid paths communicating with each other and being different in height from each other. In the cell culture device having a plurality of fluid paths, cells can be cultured by introducing a polymeric material to at least one fluid path having a relatively low height; solidifying the polymeric material to form a 3-dimensional scaffold; and injecting fluid for cell culture to a fluid path in contact with the 3-dimensional scaffold..
09/18/14
20140273222
Bioreactors for tubular organs
In one embodiment, a bioreactor includes a cartridge adapted to deliver growth media to inner and outer surfaces of a tubular organ scaffold, the cartridge having a container that includes a first passage adapted to deliver a first growth medium to the inner surfaces of the tubular organ scaffold and a second passage adapted to deliver a second growth medium to the outer surfaces of the scaffold, wherein the first and second growth media are different media.. .
09/18/14
20140273153
Covalent modification of biological macromolecules
The present disclosure provides a method of covalently modifying a biological macromolecule, the method comprising subjecting a reaction mixture comprising: (a) a biological macromolecule comprising one or more thiol groups; and (b) a molecule comprising one or more olefin or alkyne moieties to a radical reaction under conditions sufficient to produce the covalently modified biological macromolecule. The present disclosure also provides a method of covalently modifying a biological macromolecule, the method comprising subjecting a reaction mixture comprising: (a) a molecule comprising one or more thiol groups; and (b) a biological macromolecule comprising one or more olefin or alkyne moieties to a radical reaction under conditions sufficient to produce the covalently modified biological macromolecule.
09/18/14
20140272418
Bioactive glass scaffolds, and method of making
A glass, glass-ceramic, or ceramic bead is described, with an internal porous scaffold microstructure that is surrounded by an amorphous shield. The shield serves to protect the internal porous microstructure of the shield while increasing the overall strength of the porous microstructure and improve the flowability of the beads either by themselves or in devices such as biologically degradable putty that would be used in bone or soft tissue augmentation or regeneration.
09/18/14
20140271661
Monoclonal antibodies against antithrombin beta
This patent document relates to antibodies, antigen-binding antibody fragments (fabs), and other protein scaffolds, directed against human antithrombin β complexed with heparin and/or heparin-like structure (atβh). These atβh binding proteins can block the anti-coagulant activity of atβ to induce coagulation.
09/18/14
20140271660
Monoclonal antibodies against antithrombin beta
This patent document relates to antibodies, antigen-binding antibody fragments (fabs), and other protein scaffolds, directed against human antithrombin β complexed with heparin and/or heparin-like structure (atβh). These atβh binding proteins can block the anti-coagulant activity of atβ to induce coagulation.
09/18/14
20140271488
Chiral compounds of varying conformational rigidity and methods of synthesis
Synthesis of compounds having varying degrees of conformational rigidity is obtained via a low cost, high yield and efficient synthetic reactions. The library of compounds is structurally diverse having at least one or more chiral centers and providing large numbers of compounds having building block diversity and substantial scaffold diversity.
09/18/14
20140271469
Cystine knot peptides that bind alpha-v-beta-6 integrin
Disclosed are peptides comprising a molecular scaffold portion and a loop portion that binds to integrin αvβ6. This integrin is expressed on pancreatic tumors, making the peptides useful as imaging agents, among other uses.
09/18/14
20140265027
Scaffold forming system
A concrete forming system combining the ease of erection and load carrying capabilities of scaffolding with a simplified erection system. Scaffold frames provide the vertical support and walers, supported by and spanning from scaffold frame to scaffold frame, provide the horizontal support.
09/18/14
20140259639
Low diffuse scatter, anechoic chamber absorber
An electromagnetic chamber absorber provided improved absorption across a wideband and both lower diffuse and specular scatter and a method for constructing the same. An exemplary device can compromise a periodic arrangement of disconnected electromagnetically lossy elements where the periodicity of the lattice is adjusted to suppress all or most grating lobe scattering.


Popular terms: [SEARCH]

Scaffold topics: Nucleotide, Recombinant, Polynucleotide, Amino Acid, Biodegradable, Encapsulation, Surfactant, Enhancement, Monoclonal Antibody, Polypeptide, Immunogenic, Amino Acid Sequence, Monoclonal, Interleukin 2, Immune Disease

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This listing is a sample listing of patent applications related to Scaffold for is only meant as a recent sample of applications filed, not a comprehensive history. There may be associated servicemarks and trademarks related to these patents. Please check with patent attorney if you need further assistance or plan to use for business purposes. This patent data is also published to the public by the USPTO and available for free on their website. Note that there may be alternative spellings for Scaffold with additional patents listed. Browse our RSS directory or Search for other possible listings.
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