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Scaffold

Scaffold-related patent applications - as published by the U.S. Patent and Trademark Office (USPTO).


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Three-dimensional electronic scaffold for cardiac applications
Lawrence Livermore National Security, Llc
September 14, 2017 - N°20170261487

Disclosed here is a three-dimensional electronic scaffold, comprising a porous scaffold and a plurality of micro-strain gauges distributed spatially inside the porous scaffold, wherein the micro-strain gauges are adapted to detect contraction force. Also disclosed is a method comprising detecting and mapping intra-tissue cardiac contraction force of one or more cardiac cells or tissues disposed in a three-dimensional electronic scaffold, ...
Scaffold accessories
Lawrence Livermore National Security, Llc
September 14, 2017 - N°20170260810

A set of accessories for use in combination with a scaffold is comprised of at least one pair of support hooks, at least one stirrup member for facilitating stepping up or down from the scaffold, at least one material holder.
A scaffold assembly and method of manufacture
Ui Property Limited
September 14, 2017 - N°20170260759

The present invention provides a scaffold assembly, in particular a combination of a conventional tubular scaffold tube or pole and a rosette type coupling which enables the connection of additional scaffold components to the scaffold assembly, the coupling and tubular element being fixed relative to one another by means of at least one abutment which is cold formed in the ...
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Pyrimido-diazepinone kinase scaffold compounds and methods of treating disorders
Dana-farber Cancer Institute, Inc.
September 14, 2017 - N°20170260208

The present invention relates to novel pyrimido-diazepinone compounds, methods of modulating protein kinases, including mps1 (ttk), erk5 (bmk1, mapk7), polo kinase 1, 2, 3, or 4, ack1, ack2, abl, dcamkl1, abl1, abl mutants, dcamkl2, ark5, brk, mknk2, fgfr4, tnk1, plk1, ulk2, plk4, prkd1, prkd2, prkd3, ros1, rps6ka6, taok1, taok3, tnk2, bcr-abl, gak, csrc, tpr-met, tie2, met, fgfr3, aurora, axl, bmx, btk, c-kit, chk2, ...
2-imidazolyl-pyrimidine scaffolds as potent and selective inhibitors of neuronal nitric oxide synthase
Northwestern University
September 14, 2017 - N°20170260165

Imidazolyl-pyrimidine and related compounds, as can utilize heme-iron coordination in the selective inhibition of neuronal nitric oxide synthase.
Porous structures of microbial-derived cellulose in vivo implantation
Depuy Synthes Products, Inc.
September 14, 2017 - N°20170258964

This invention elates to polysaccharide materials and more particularly to microbial-derived cellulose having the porosity and containing pores of the desired size making it suitable for cellular infiltration during implantation and other desirable properties for medical and surgical applications. The invention also relates to the use of porous microbial-derived cellulose as tissue engineering matrices, human tissue substitutes, and reinforcing scaffolds ...
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Medical/surgical implant
Klinikum Rechts Der Isar Der Technischen Universität München
September 14, 2017 - N°20170258574

The present invention relates to the field of implants. In particular, the present invention relates to an implant for tissue reconstruction which comprises a scaffold structure that includes a void system for the generation of prevascularized connective tissue with void spaces for cell and/or tissue transplantation. Moreover, the present invention relates to a method of manufacturing such an implant, ...
Silk medical device for use in breast augmentation and breast reconstruction
Sofregen Medical Ireland Limited
September 14, 2017 - N°20170258573

A three-dimensional fabric structure in a form of a pocket for use in a breast reconstruction surgical procedure such as single-stage or two-stage breast reconstruction. The silk scaffold employs a knit pattern that substantially prevents unraveling and preserves the stability of the mesh or scaffold device, especially when the mesh or scaffold device is cut. An example scaffold device employs ...
Systems, methods and processes for scaffolding coordination conversations
Coo-e Llc
September 07, 2017 - N°20170255889

The present disclosure relates to a software system or application or tool, referred to here as “coo-e coordinator” that provides group communication and new methods, processes and techniques for the support social activity coordination.
Flame resistant yarns and fabrics including partially aromatic polyamide fiber and other flame resistant fibers
Invista North America S.a.r.l.
September 07, 2017 - N°20170254000

Disclosed are technical fibers and yarns made with partially aromatic polyamides and a fiber having vapor phase action such as an fr cellulosic fiber. Fabrics made from such fibers and yarns demonstrate superior flame retardancy over traditional flame retardant nylon 6,6 fabrics. Further, the disclosed fibers and yarns, when blended with other flame retardant fibers, do not demonstrate the dangerous ȁ...
Apparatus and method for manufacturing channel-coupled scaffold
Korea Institute Of Science And Technology
September 07, 2017 - N°20170253860

The present disclosure relates to an apparatus and a method for manufacturing a channel-coupled scaffold. The present disclosure provides a method for manufacturing a channel-coupled scaffold, which includes: (1) a step of compressing a first elastic substrate which includes a groove on the surface of the substrate to close the groove; (2) a step of loading a scaffold composition onto the closed ...
Cardiomyocyte maturation platform
The Regents Of The University Of California
September 07, 2017 - N°20170253858

Disclosed herein are methods of inducing and/or promoting cardiomyocyte maturation comprising: providing an immature cardiomyocyte; providing a three dimensional (3d) cardiac extracellular matrix (ecm) scaffold; and inducing and/or promoting cardiomyocyte cell maturation by seeding the immature cardiomyocyte in the 3d cardiac ecm scaffold and harvesting once the cardiomyocyte has reached maturity. Also disclosed herein are methods of treating ...
Anion exchange polymers and anion exchange membranes incorporating same
Xergy Inc.
September 07, 2017 - N°20170252707

An anion exchange membrane is made by mixing 2 trifluoromethyl ketone [nominal] (1. 12 g, 4. 53 mmol), 1 biphenyl (0. 70 g, 4. 53 mmol), methylene chloride (3. 0 ml). Trifluoromethanesulfonic acid (tfsa) (3. 0 ml) to produce a pre-polymer. The pre-polymer is then functionalized to produce an anion exchange polymer. The pre-polymer may be functionalized with trimethylamamine in solution with water. The pre-polymer may be imbibed into a porous scaffold material, such ...
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Esophageal stent including a valve member
Boston Scientific Scimed, Inc.
September 07, 2017 - N°20170252144

An example medical device is disclosed. The example medical device includes a tubular scaffold. The scaffold includes a longitudinal axis, an inner surface and an outer surface. The medical device also includes a flexible valve extending radially inward from the inner surface of the scaffold. The valve includes an annular chamber extending circumferentially around the inner surface of the scaffold ...
Display of binding agents
F-star Biotechnologische Forschungs- Und Entwicklungsges.m.b.h
August 31, 2017 - N°20170247432

The present application relates to a method of preparing a genetic package displaying oligomers of modular antibody domains binding to a target and to a scaffold ligand as well as to vectors and libraries of genetic packages produced thereby. The invention further relates to methods of selecting suitable linker sequences for use in such oligomer display.
"bioengineered human corneal stromal tissue"
University Of Pittsburgh - Of The Commonwealth System Of Higher Education
August 31, 2017 - N°20170246350

Provided herein is a method of making an aligned ecm scaffold useful in refractive correction of the eye and repair of the cornea. Methods of use of the scaffold as well as a scaffold construct are provided.
A method for producing a hap (hydroxyapatite)/boron-doped hap and developing composite tissue scaffolds
University Of Pittsburgh - Of The Commonwealth System Of Higher Education
August 31, 2017 - N°20170246346

The present invention relates to a method for producing biomimetic hydroxyapatite (hap) and boron-doped hap (b-hap) with the support of microwave and a method for coating tissue scaffolds with hap and/or b-hap.
Energy-providing bone-repair degradable porous scaffold, preparation method thereof, and application thereof
Huazhong University Of Science And Technology
August 31, 2017 - N°20170246343

The invention discloses an energy-providing bone-repair degradable porous scaffold, a preparation method thereof, and an application thereof. The invention obtains an energy-based biomaterial solution by compositing gelatin, a polyatomic acid and derivatives thereof, a dibasic alcohol and derivatives thereof, and a tribasic alcohol and derivatives thereof in a chemical cross-linking manner by using diisocyanate, and further obtains a porous scaffold ...
Pathogen vaccines and methods of producing and using the same
President And Fellows Of Harvard College
August 31, 2017 - N°20170246281

The present invention provides vaccine compositions and methods of producing such compositions. Other embodiments of the invention include methods of treating a pathogen infection, methods of vaccinating a subject against a pathogen infection, and methods for treating an antibiotic-resistance bacterial infection in a subject in need thereof. In further embodiments, the invention includes methods of decreasing the level of a ...
Bioresorbable scaffold for treatment of bifurcation lesion
Amaranth Medical Pte.
August 31, 2017 - N°20170246243

Bioresorbable scaffolds for treatment of bifurcation lesion are described herein. Generally, an expandable scaffold may be fabricated from a high molecular weight isotropic plla material, wherein the scaffold incorporates one or more strain relief features which are configured to allow side branch treatment.
Bone regeneration device
Industry-academic Cooperation Foundation Gyeongsang National University
August 31, 2017 - N°20170245996

Disclosed is a bone regeneration device which forms an electric field on a scaffold inserted into a bone damage site. The present bone regeneration device comprises: a battery; a first electric conductor to be connected to a first electrode of the battery and inserted into a bone located on one side of the scaffold; and a second electric conductor to ...
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