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Scaffold patents

      

This page is updated frequently with new Scaffold-related patent applications.




 Apparatus and  securing planks patent thumbnailApparatus and securing planks
The invention comprises a clamp that is easily and quickly attached to planks such as those in a scaffold platform that is defined by plural planks laid side-by-side to define a platform in a scaffold structure. The clamp resides beneath the planks and is therefore not a trip-hazard for workers, and the clamp is readily adjustable to compress the planks to one another to stabilize the platform.
Ckh, Inc.


 Coating method and materials patent thumbnailCoating method and materials
A system consisting of a component coating a particulate scaffold is able to transfer the coating to an exposed surface in order to yield beneficial effects. The system is useful for many applications, including the treatment of individuals suffering from a disease, cancer, an ailment, an infection, a toxin, or other syndrome, as well as for numerous non-treatment purposes requiring the coating of exposed surfaces..

 Coating method and materials patent thumbnailCoating method and materials
A system consisting of a component coating a particulate scaffold is able to transfer the coating to an exposed surface in order to yield beneficial effects. The system is useful for many applications, including the treatment of individuals suffering from a disease, cancer, an ailment, an infection, a toxin, or other syndrome, as well as for numerous non-treatment purposes requiring the coating of exposed surfaces..

 Biocompatible smart responsive scaffold having interconnected pores patent thumbnailBiocompatible smart responsive scaffold having interconnected pores
A polymeric scaffold contains pendant liquid crystal side chains and has fully interconnected pores. Such a polymeric scaffold will preferably be 3d in nature and elastomeric, biocompatible and biodegradable.
Kent State University


 A ready to use biodegradable and biocompatible device and a  preparation thereof patent thumbnailA ready to use biodegradable and biocompatible device and a preparation thereof
The invention provides a ready to use biodegradable and biocompatible device and a method for manufacturing thereof. The device of present invention is a novel porous scaffold which can be used as carrier of plurality of therapeutics to quickly stop bleeding and other biomaterial and biomedical application.
Datt Mediproducts Limited


 Precise delivery of therapeutic agents to cell mitochondria for anti-cancer therapy patent thumbnailPrecise delivery of therapeutic agents to cell mitochondria for anti-cancer therapy
Described is a targeted molecular scaffold for construction of a metabolic inhibitor loaded with cancer-cell specific activity and anti-tumor immunity. Incorporation of a mitochondria targeting moiety such as triphenylphosphonium cation through a biodegradable linker in allowed for mitochondria targeting of certain metabolic inhibitors like dichloroacetic acid (dca)..
University Of Georgia Research Foundation Inc


 Novel peptides and combination of peptides and scaffolds thereof for use in immunotherapy against colorectal carcinoma (crc) and other cancers patent thumbnailNovel peptides and combination of peptides and scaffolds thereof for use in immunotherapy against colorectal carcinoma (crc) and other cancers
The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer.
Immatics Biotechnologies Gmbh


 Locked segments pushable stent-graft patent thumbnailLocked segments pushable stent-graft
An implantable prosthesis includes a scaffold with a plurality of expandable segments axially spaced apart along a substrate, adjacent segments connected by one or more support members when the prosthesis is in a collapsed configuration and disconnected when the prosthesis is in an expanded configuration.. .
C. R. Bard, Inc.


 Systems and methods for repairing soft tissues patent thumbnailSystems and methods for repairing soft tissues
A wicking component is integrated into an arthroscopically deployable bone anchor, and is intended to improve soft tissue-to-bone repair. Once deployed, the fibrous wick component extends from within the bone tunnel, out of the hole, and to the bone-tendon interface on the bone surface.
Cayenne Medical, Inc.


 Multimodal trail molecules and uses in cellular therapies patent thumbnailMultimodal trail molecules and uses in cellular therapies
Described herein are novel compositions comprising multimodal trail agents and cells engineered to express such multimodal trail agents, including cells encapsulated in a scaffold or matrix, for use in the treatment of disorders such as cancer.. .
The General Hospital Corporation


Small-molecule hsp90 inhibitors

Purine scaffold hsp90 inhibitors are useful in therapeutic applications and as radioimaging ligands.. .
Sloan-kettering Institute For Cancer Research

Selective immunoproteasome inhibitors with non-peptide scaffolds

Methods and compounds for inhibiting the immunoproteasome, particularly, immunoproteasome inhibitors with non-peptide scaffolds, are described.. .

Sortilin-binding small molecules for increasing glucose uptake

Various scaffolds of small molecules capable of binding to the active site of sortilin are identified by in silico methods. These scaffolds include norbornene anhydride amino acid adducts, phenyl-amide-acids of benzyl substituted glutaric acids, and 2-substituted 3-oxo-1,2,3,4-tetrahydro-2-quinoxalines.
The United States Government As Represented By The Department Of Veterans Affairs

Bioabsorbable polymeric medical device

In embodiments there is described a cardiovascular tube-shaped lockable and expandable bioabsorbable scaffold having a low immunogenicity manufactured from a crystallizable bioabsorbable polymer composition or blend.. .
Orbusneich Medical, Inc.

Macroporous 3-d scaffolds for tissue engineering

Macroporous 3-d tissue engineering scaffold comprising elastomeric cross-linked polymer units and interconnected macropores containing living cells are produced by step of: in a mixture of the cells and elastomeric polymer units comprising activatable crosslinking groups, activating the crosslinking groups to form the scaffold.. .
The Board Of Trustees For The Leland Stanford Junior University

Method for improvement of differentiation of mesenchymal stem cells using a double-structured tissue implant

A double-structured tissue implant (dsti) and a method for preparation and use thereof for implantation into tissue defects. The double-structured tissue implant for differentiation, growth and transformation of cells, stem cells, mesenchymal stem cells and bone marrow stem cells.
Histogenics Corporation

Systems and methods for producing and applying tissue-related structures

Embodiments produce and apply tissue-related structures in connection with various medical treatments. Such structures can be applied, as grafts, implants, scaffolds, etc., to replace, modify, or engineer tissue in the body.

Device for soft tissue repair or replacement

Disclosed are composite implantable tissue attachment devices comprising a mechanical reinforcing component and a cellular scaffold component. Disclosed devices include a wide, relatively flat portion for supporting long term repair of tissue.
Synovis Orthopedic And Woundcare, Inc.

Composite synthetic nanofibrous scaffolds and articles thereof

A synthetic scaffold that comprises a population of nanofibers that include collagen and an anti-thrombotic glycan is provided. In addition, a method of making the synthetic scaffold is provided.
3m Innovative Properties Company

Fiber scaffolds for use in esophageal prostheses

The development and construction of implantable artificial organs, and a process for manufacturing three-dimensional polymer microscale and nanoscale structures for use as scaffolds in the growth of biological structures such as hollow organs, luminal structures, or other structures within the body are disclosed.. .
Nanofiber Solutions, Inc.

Biohybrid composite scaffold

A biohybrid scaffold is provided that is useful in clinical applications for abdominal wall reconstruction, pelvic floor repair, breast reconstruction, as well as other soft tissue repairs. Methods of making and using the biohybrid scaffold are provided..
University Of Pittsburgh - Of The Commonwealth System Of Higher Education

Biomimetic scaffolds

The invention provides a composition comprising a nanofiber polymer in which the fibers of the nanofiber polymer arc aligned, and a molecule is covalcntly attached, either directly or through a linker, to the nanofiber polymer. This molecule is capable of either covalently or non-covalently attaching to a member selected from an extracellular matrix component, a growth factor, and combinations thereof.
The Regents Of The University California

Reversible pegylated drugs

Reversible pegylated drugs are provided by derivatization of free functional groups of the drug selected from amino, hydroxyl, mercapto, phosphate and/or carboxyl with groups sensitive to mild basic conditions such as 9-fluorenylmethoxycarbonyl (fmoc) or 2-sulfo-9-fluorenylmethoxycarbonyl (fms), to which group a peg moiety is attached. In these pegylated drugs, the peg moiety and the drug residue are not linked directly to each other, but rather both residues are linked to different positions of the scaffold fmoc or fms structure that is highly sensitive to bases and is removable under physiological conditions.
Yeda Research And Development Co., Ltd.

Porous orthopedic or prosthetic support having removable cushioning and scaffolding layers

An orthopedic or prosthetic support including at least three layers that allows for aeration and cushioning of the enclosed area is described herein. The orthopedic or prosthetic support includes an inner cushioning layer which is compressed against the skin in use.

Adrenomedullin binder for use in therapy of cancer

Subject matter of the present invention is an anti-adm antibody or anti-adm antibody fragment or anti-adm non-ig scaffold binding to the c-terminal portion of adm, the aa 43-52 of adm (seq id no: 1): aprskispqgy-nh2 for use in a therapy of cancer. Subject matter of the present invention is anti-adm antibody or anti-adm antibody fragment or anti-adm non-ig scaffold for use in the treatment of cancer according to claim 1 wherein said anti-adm antibody or anti-adm antibody fragment or anti-adm non-ig scaffold requires the presence of a c-terminally amidated tyrosine residue within the c-terminal portion of adm, the aa 43-52 of adm (seq id no: 1): aprskispqgy-nh2, for binding..
Angiobiomed Gmbh

Biodegradable supporting device

A biodegradable in vivo supporting device is disclosed. The in vivo supporting device comprises a biodegradable metal scaffold and a biodegradable polymer coating covering at least a portion of the biodegradable metal scaffold, wherein the biodegradable polymer coating has a degradation rate that is faster than the degradation rate of the biodegradable metal scaffold..
Q3 Medical Devices Limited

Double-structured tissue implant and a preparation and use thereof

A double-structured tissue implant and a method for preparation and use thereof for implantation into tissue defects. The double-structured tissue implant comprising a primary scaffold and a secondary scaffold consisting of a soluble collagen solution in combination with a non-ionic surfactant generated and positioned within the primary scaffold.
Histogenics Corporation

Liquefaction of bone matrix

The invention relates to methods of preparing a bone matrix solution, a bone matrix implant, and variants thereof. The invention also relates to methods of cell culture using the same.
Lifenet Health

Multi-component electrospun fiber scaffolds

A scaffold may comprise a first polymeric electrospun fiber comprising a first material having a first degradation rate, and a second polymeric electrospun fiber comprising a second material having a second degradation rate different from the first degradation rate. The first degradation rate may substantially correspond to a cell infiltration rate, and the second degradation rate may be slower than the first degradation rate.
Nanofiber Solutions, Inc.

Programming of cells for tolerogenic therapies

Biomaterial systems, e.g., gel scaffolds, are used in vivo to recruit immune cells and promote their activation towards a non-inflammatory phenotype, thereby leading suppression of inflammation. The compositions and methods are useful to reduce the severity of autoimmunity, chronic inflammation, allergy, and periodontal disease..
Forsyth Dental Infirmary For Children

Bioactive collagen biomaterials and methods for making

A bioactive collagen biomaterial according to the invention that is biocompatible with cells and tissues and distinguished by containing certain cryptic and non-cryptic peptide constituents to stimulate cellular responses and further made to incorporate a variety of agents to provide a desired characteristic, such as antimicrobial properties. The bioactive collagen biomaterial can be provided as a variety of configurations and as various matrices and devices for use in medical applications such as in biotechnology, basic research, tissue engineering and in wound repair as a wound dressing or cell/tissue scaffold..

Purified amphiphilic peptide compositions and uses thereof

A plurality of amphiphilic peptide chains having alternating hydrophilic and hydrophobic amino acids, wherein the peptide contains at least 8 amino acids, are complementary and structurally compatible, and self-assemble into a beta-sheet macroscopic scaffold wherein peptide at least about 75% of the chains have the same sequence.. .
3d Matrix, Inc.

Striped sheaths for medical devices

A sheath used to protect a medical device has one or more strips formed over a portion thereof. The medical device is a scaffold crimped to a balloon and mounted to a catheter.
Abbott Cardiovascular Systems Inc.

Striped sheaths for medical devices

A sheath used to protect a medical device has one or more strips formed over a portion thereof. The medical device is a scaffold crimped to a balloon and mounted to a catheter.
Abbott Cardiovascular Systems Inc.

Biodegradable supporting device

A biodegradable in vivo supporting device is disclosed. The in vivo supporting device comprises a biodegradable metal scaffold and a biodegradable polymer coating covering at least a portion of the biodegradable metal scaffold, wherein the biodegradable polymer coating has a degradation rate that is faster than the degradation rate of the biodegradable metal scaffold..
Q3 Medical Devices Limited

Bone intramedullary fixation scaffold

A new shape changing bone implant and instrument for the fixation of structures to include bone tissue. This new implant stores elastic mechanical energy to exert force on fixated structures to enhance their security and in bone affect its healing response.

Cow antibody scaffold polypeptide method and composition

This invention relates to a method of selecting a peptide using an mrna-displayed cow antibody scaffold polypeptide. The invention also relates to the mrna-displayed cow antibody scaffold polypeptide comprising a peptide of interest or to a peptide microarray comprising the cow antibody scaffold polypeptide comprising a peptide of interest or to a peptide microarray comprising a peptide of interest as described herein..
Roche Sequencing Solutions, Inc.

Substituted nucleoside derivatives with antiviral and antimicrobial properties

The present invention relates to fatty acid and fatty alcohol substituted nucleoside derivatives and nucleoside and nucleoside derivatives substituted on multivalent scaffolds (e.g., polymers, peptides, polycarboxylic acid substituted compounds, compounds containing polycyclosaligenyl groups) that display potent anti-hiv activity. Furthermore, they show enhanced activity against multi-drug resistant, r5, and cell-associated virus.
Board Of Governors For Higher Education, State Of Rhode Island And Providence Plantations

Injectable hierarchical scaffolds

The present invention relates to a three-dimensional biocompatible scaffold capable of supporting cell activities, such as growth and differentiation, the scaffold comprising a first biocompatible material and a second biocompatible material, said second material filling a substantial part of the first voids shaped by said first biocompatible material, wherein the scaffold has a diameter of less than 500 μm.. .
Aarhus Universitet

3-dimensional parylene scaffold cage

Thin parylene c membranes having smooth front sides and ultrathin regions (e.g., 0.01 μm to 5 μm thick) interspersed with thicker regions are disclosed. The back sides of the membranes can be rough compared with the smooth front sides.
University Of Southern California

Reinforcement scaffolds for maintaining a reduced size of a stomach and methods of use

A method of performing bariatric surgery includes inserting a gastrectomy device into a stomach of a patient, positioning the gastrectomy device in a selected location in the stomach, transecting a portion of the stomach thereby reducing a size of the stomach, and applying a reinforcement scaffold to an outer surface of the stomach. The reinforcement scaffold is configured to maintain the reduced size of the stomach..
Covidien Lp

Bioengineered vocal fold mucosa for functional voice restoration

An engineered vocal fold mucosa, including an engineered lamina propria layer and an engineered squamous epithelium layer, is disclosed. The engineered lamina propria is made by seeding and culturing human vocal fold fibroblasts within a polymerized collagen scaffold, and the engineered squamous epithelium is made by culturing human vocal fold epithelial cells on the scaffold surface.
Wisconsin Alumni Research Foundation

Mechanically stiff, electrically conductive composites of polymers and carbon nanotubes

Using swnt-ca as scaffolds to fabricate stiff, highly conductive polymer (pdms) composites. The swnt-ca is immersing in a polymer resin to produce a swnt-ca infiltrated with a polymer resin.
Lawrence Livermore National Security, Llc

Scaffold and method

A scaffold includes a first end frame assembly. The scaffold includes a second end frame assembly.
Werner Co.

In vivo generating diversity in a protein scaffold

A transgenic non-human animal is provided. In certain embodiments, the animal comprises a genome comprising an immunoglobulin heavy chain locus comprising: a) a transcribed gene encoding a fusion protein comprising, from n-terminus to c-terminus: i.
Crystal Bioscience Inc.

Novel nitric oxide-eluting bioresorbable stents for percutaneous coronary interventions

Disclosed herein are bioresorbable stents which elute nitric oxide (no). The stent is comprised of three main key design elements: a bioresorbable scaffold, a bioresorbable polymeric coating layer(s), and no-releasing nanoparticles incorporated in the bioresorbable polymeric coating layer, and optionally also in the scaffold.
Heart Biotech Limited

Thin film with microchannels

A scaffold, a method of using the scaffold and a method of preparing the scaffold which may promote the growth or survival of cells and tissues. The scaffold comprises at least one microvascular layer formed from a thin-film fibrin, the microvascular layer configured to sustain and promote growth of cells and having one or more microfluidics channels embedded in the microvascular layer, the channels configured to contain nutrients needed for growth of the cells, and the channels configured to permit diffusion of the nutrients from the channels to the cells..
Worcester Polytechnic Institute

Intervertebral scaffolding with stabilized laterovertical expansion

An intervertebral scaffolding system is provided having a laterovertically-expanding frame operable for a reversible collapse from an expanded state into a collapsed state, the laterovertically-expanding frame having a stabilizer that slidably engages with the distal region of the laterovertically-expanding frame and is configured for retaining the laterovertically-expanding frame from a lateral movement that exceeds the expanded state. The expanded state, for example, can be configured to have an open graft distribution window that at least substantially closes upon the reversible collapse..
Integrity Implants Inc.

Dynamic bioactive nanofiber scaffolding

A resorbable bone graft scaffold material, including a plurality of overlapping and interlocking fibers defining a scaffold structure, plurality of pores distributed throughout the scaffold, and a plurality of glass microspheres distributed throughout the pores. The fibers are characterized by fiber diameters ranging from about 5 nanometers to about 100 micrometers, and the fibers are a bioactive, resorbable material.
Mo-sci Corporation

Dynamic bioactive nanofiber scaffolding

A resorbable bone graft scaffold material, including a plurality of overlapping and interlocking fibers defining a scaffold structure, plurality of pores distributed throughout the scaffold, and a plurality of glass microspheres distributed throughout the pores. The fibers are characterized by fiber diameters ranging from about 5 nanometers to about 100 micrometers, and the fibers are a bioactive, resorbable material.
Mo-sci Corporation

Valve seat

A valve seat (10) comprises a substantially annular rigid scaffold member (12) and a substantially annular elastomeric sealing member (14) sealingly mounted on top of the rigid scaffold member. The valve seat has an outer peripheral surface for cooperation with the valve body of a valve assembly, and the elastomeric sealing member defines an inner sealing surface of the valve seat for cooperation with a valve closure disc of a valve assembly..
Chargepoint Technology Limited

Fall protection guardrail

A fall protection guardrail system and method used for construction of multi-story wood-framed buildings, which comprises a support bracket comprised of an attachment member and a pole support, and further comprises a pole with integrated rail supports. For a framed wall that is lying in a horizontal position, the support bracket is easily attached to a framing member of the framed wall, and the pole is inserted into the pole support.

Cup connector for scaffold

A cup lock connection system for scaffold equipment advantageously has a locating arrangement for aligning ledgers, braces and other components on the cup lock at predetermined angular positions relative to the scaffold upright. The connecting ledgers, braces and other components preferably have a connecting head receivable on the cup lock connection in one of two orientations.
Athos Construction Products Inc.

Liver-mimetic device and simulation of hepatic function using such device

A liver-mimetic device and method include a 3d polymer scaffold having a matrix of liver-like lobules with hepatic-functioning particles encapsulated within the lobules. In some embodiments, each liver-like lobule is hexagonal in structure and the matrix is in a honeycomb arrangement.
The Regents Of The University Of California

Step device

A step device may include a step housing having a box shape, guide rails mounted on both sides of the step housing, step rails coupled to the guide rails to move along the guide rails, and a scaffold coupled to the step rails and moving along the guide rails through the step rails to be received in the step housing or drawn to an outside of the step housing.. .
Hyundai Motor Company

Modification of bioabsorbable stent to reduce thrombogenecity

Bioabsorbable polymer scaffolds with coatings are disclosed that include immobilized antithrombotic agents on the scaffolds or in or on the coatings. The agents act synergistically with antiproliferative agents released from coatings by providing hemocompatibility during and without interfering with antiproliferative agent release.
Abbott Cardiovascular Systems Inc.

Methods for host cell homing and dental pulp regeneration

Hydrogel-based scaffolds useful for promoting pulp cell growth and biosynthesis, regulating pulp cell migration and morphology, or both as well as methods for their production and use are provided.. .
The Trustees Of Columbia University In The City Of New York

Synergistic glycocalyx treatment compositions and methods

Compositions and methods for treating endothelial glycocalyx include glucosamine, hyaluronan and/or fucoidan, and one or more antioxidants, such as superoxide dismutase, catalase, and/or polyphenol. The compositions improve vascular health by exhibiting beneficial synergistic effects on endothelial glycocalyx over the benefits of taking any single component alone or the sum of reported effects of the individual components.
Microvascular Health Solutions, Llc

Vascular stent

A vascular stent (1) for scaffolding a vessel (11) from the inside, wherein the stent is provided with a plurality of tube-forming elements (3a), (3b), and (3c) for forming a tube (2), the tube-forming elements combining with each other to construct a single flow path. Each of the tube-forming elements is formed by bending a strand comprising a single continuous biodegradable polymer, and first and second projecting parts (4, 5) are formed by successive alternation.
Kyoto Medical Planning Co., Ltd.

Electrospun ptfe encapsulated stent and manufacture

A stent or other prosthesis may be formed by encapsulating a scaffold or frame with a polymer coating. The polymer coating may consist of layers of electrospun polytetrafluoroethylne (ptfe).
Zeus Industrial Products, Inc.

Ultrasound devices methods and systems

Ultrasound methods, devices, and systems are described which support a useful compromise in terms of spatial resolution and temporal resolution for capturing motion in tissue structures. Tissue engineering articles, methods, systems, and devices which employ ultrasound to deliver biological agents to selected regions of a tissue scaffold, deliver mechanical stimulation to cells growing in a tissue scaffold, and enhance the perfusion of fluids through tissue scaffolds..
The Trustees Of Columbia University In The City Of New York

Method for providing and assembling scaffolding units, each of which will be assembled from individual scaffolding components for constructing an industrial plant, in particular a petroleum refinery

J) beginning of assembly of the scaffolding units to be used in a respective phase of construction from the scaffolding components each required for this purpose on-site at a point in time chosen in dependency of the specified erection time each at the latest prior to a start of construction in the respective section of construction specified in the construction schedule.. .

Method for construction of an industrial plant

Building of the industrial plant according to the modified construction plan and by use of the scaffolding units drawn in the 3d construction plan. The method according to the invention, allows for a significant reduction of scaffolding costs incurred during the construction of any industrial plant.

Apparatus for building complex 3d biomimetic scaffolds

A system and apparatus for constructing complex three-dimensional scaffolds that takes advantage of the physical and chemical properties of gelatin-sugar hydrogels. Novel apparatus for building complex three-dimensional scaffolds for biomimetic applications such as in vitro organ growth, using a gelatin/sugar/water gel, ultraviolet radiation, and heat or enzyme are described.

Novel peptides and combination of peptides and scaffolds for use in immunotherapy against renal cell carcinoma (rcc) and other cancers

The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer.
Immatics Biotechnologies Gmbh

Mono-ethers of isohexides and process for making the same

A method of making a mono-ether of an isohexide and art assemblage of novel. Song-chain isohexide mono-ethers are described.
Archer Daniels Midland Company

Selective fkbp51 ligands for treatment of psychiatric disorders

The present invention relates to compounds of the general formula (i) having a selective fkbp51 ligand scaffold, pharmaceutically acceptable salts of these compounds and pharmaceutical compositions containing at least one of these compounds together with pharmaceutically acceptable carrier, excipient and/or diluents. Said selective fkbp51 ligand compounds can be used for prophylaxis and/or treatment of psychiatric disorders and neurodegenerative diseases, disorders and conditions..
Max-planck-gesellschart Zur FÖrderung Der Wissensc Haften E.v.

Bioprinter and methods of using same

A bioprinter and methods of using the bioprinter. The bioprinter permits selective three-dimensional movement of multiple nozzle assemblies during operation of the bioprinter.
University Of Iowa Research Foundation

Tissue scaffold materials for tissue regeneration and methods of making

Disclosed herein are tissue scaffold materials with microspheres of one density embedded in hydrogel of a different density. The disclosed materials have improved ability to facilitate cellular invasion and vascularization for wound healing and tissue regeneration.
Cornell University

Method for preparing bilayer scaffold through single process and regenerating tissue using bilayer scaffold obtained by preparing method

Disclosed is a method for preparing a bilayer scaffold through single process comprising: preparing a first polymer aqueous solution; adding a second polymer into the first polymer aqueous solution and stirring a reactant; adding a surfactant into the stirred reactant and stirring the reactant at high temperature and high speed; freeze-drying the stirred reactant thereby obtaining a sponge; dipping the sponge in a cross-linking agent thereby rendering be cross-linked; and freeze-drying the cross-linked reactant.. .
Research Cooperation Foundation Of Yeungnam University

Novel peptides and combination of peptides and scaffolds for use in immunotherapy against renal cell carcinoma (rcc) and other cancers

The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer.
Immatics Biotechnologies Gmbh

Tissue repair material derived from fish skin and manufacturing method thereof

A tissue repair material derived from fish skin and manufacturing method thereof is applied to provide the tissue repair material suitable for use as a patch, a cover, a carrier, a scaffold, an implant or a reagent in various tissues. The tissue repair material has collagens to improve the wounded tissue repair, and has particular characters for desired tissue repair application.
Body Organ Biomedical Corp.

Scaffold system for tissue repair

A device for treating a damaged tissue includes an expandable scaffold positionable in a portion of a luminal tissue structure of a mammal; and maintained via stent technology, wherein the scaffold is comprised of electrospun fibers composed of a biodegradable compound. The scaffold serves as a temporary template that allows the tissue to be rebuilt..
The Board Of Regents Of The University Of Texas System

Devices and methods for dilating a lumen of a body

Methods and devices for dilating a stricture of a body lumen are disclosed. In some embodiments, a device for dilating a lumen of a body comprises an elongate member having a proximal end and a distal end and an inflatable scaffold member disposed on the distal end of the elongate member, the inflatable scaffold member defining a lumen.
Boston Scientific Scimed, Inc.

Micro-sampling for cell, tissue, and micro-organism monitoring

Cell and organ (or tissue) cultures provide a micro-environment with respect to nutrients, gas exchange, and scaffolding in order to encourage specific cell function, and in some cases to mimic in-vivo cellular expression under in-vitro conditions. We describe apparatus and methods to chemically, spatially, and temporally measure diffusible molecules produced, or used by cells or tissues in culture.
Biomicom Incorporated

Cup connector for scaffold

A cup lock connection system for scaffold equipment advantageously has a locating arrangement for aligning ledgers, braces and other components on the cup lock at predetermined angular positions relative to the scaffold upright. The connecting ledgers, braces and other components preferably have a connecting head receivable on the cup lock connection in one of two orientations.
Athos Construction Products Inc.

Liver tissue culturing device, liver tissue culturing system, liver tissue culturing method, and liver function evaluation method

A device for culturing a liver tissue has a culture chamber to which at least two flow channels, which are at least for introducing and discharging a culture medium, are connected. A gel which serves as a cell scaffold material is housed in the culture chamber.
Tokyo Institute Of Technology

Methods and devices for high-throughput manufacture of user desired 3d polymeric scaffolds

Biomedical devices and methods are disclosed for the development of 3d polymeric scaffolds for cell culture, high throughput screens for biomolecule purification, and generation of bone mimetic materials. The devices may feature multiple geometries, and scaffold generation capabilities include multiple gel types utilizing organic and aqueous phase pregel.
Arizona Board Of Regents On Behalf Of Arizona State University

Glycation cross-link breakers to increase resistance to enzymatic degradation

The present invention relates to a method to treat a grafts, implant, scaffold, and constructs, including allografts, xenografts, autografts, and prosthetics comprising collagen, with an inhibitor of collagen cross-links and/or advanced glycation endproducts (age), in order to alleviate the mechanical weakness induced by the cross-links. The invention also provides for kits for use in the operating theater during autograft, allograft or xenograft procedures, or for preparing allograft, xenografts or prosthetics that have not been already treated prior to packaging.
Cornell University

System and sealing an incisional wound

An apparatus, system, and method for treating an incisional wound having incisional walls is disclosed. The apparatus includes a conduit having a first end for receiving reduced pressure and a second end.
Kci Licensing, Inc.

Controllable self-annealing microgel particles for biomedical applications

A microporous gel system for certain applications, including biomedical applications, includes an aqueous solution containing plurality of microgel particles including a biodegradable crosslinker. In some aspects, the microgel particles act as gel building blocks that anneal to one another to form a covalently-stabilized scaffold of microgel particles having interstitial spaces therein.
The Regents Of The University Of California

Scaffolds for cell transplantation

A device that includes a scaffold composition and a bioactive composition with the bioactive composition being incorporated into or coated onto the scaffold composition such that the scaffold composition and/or a bioactive composition controls egress of a resident cell or progeny thereof. The devices mediate active recruitment, modification, and release of host cells from the material..
Regents Of The University Of Michigan

Scaffolds for cell transplantation

A device that includes a scaffold composition and a bioactive composition with the bioactive composition being incorporated into or coated onto the scaffold composition such that the scaffold composition and/or a bioactive composition controls egress of a resident cell or progeny thereof. The devices mediate active recruitment, modification, and release of host cells from the material..
Regents Of The University Of Michigan

Ultrasound-triggerable agents for tissue engineering

The present invention is directed to compositions and methods for delivering a tissue scaffold comprising ultrasound-triggerable agents to an individual.. .
The Regents Of The University Of Michigan

Processes for making crush recoverable polymer scaffolds

Methods for making scaffolds for delivery via a balloon catheter are described. The scaffold, after being deployed by the balloon, provides a crush recovery of about 90% after the diameter of the scaffold has been pinched or crushed by 50%.
Abbott Cardiovascular Systems Inc.

A fluorescent chemical sensor for biological amines

The invention is provides for a variety of fluorescence sensing compounds characterized generally as having a coumarin-3-aldehyde scaffold with a pendant aryl moiety at the c4-position of the scaffold. The further provides a method for detecting primary amines in a biological sample using said compounds.
The Curators Of The University Of Missouri

Hydrogen generating system

The present invention relates to a solid fuel, a system and a method for generating hydrogen. The solid fuel comprises sodium borohydride, catalyst loaded fibres and a binder, wherein the catalyst loaded fibres and the binder form a scaffold structure within which the sodium borohydride is positioned.
Temasek Polytechnic

Apparatus and embedding cable in 3d printed objects

Additive manufacturing method and apparatus for embedding cable in articles of additive manufacture in cooperation with a filament extrusion nozzle to increase their strength and functionality. This capability can be provided autonomously by integrating cable guides and cable cutters with new or existing print heads, enabling them to transition between filament-only, cable-only, and combined cable and filament printing modes to form mechanically stronger objects, integrated circuits within objects, and cable alternatives to filament scaffolding..

Scaffolds for cell transplantation

A device that includes a scaffold composition and a bioactive composition with the bioactive composition being incorporated into or coated onto the scaffold composition such that the scaffold composition and/or a bioactive composition controls egress of a resident cell or progeny thereof. The devices mediate active recruitment, modification, and release of host cells from the material..
Regents Of The University Of Michigan

Coating scaffolds

Provided are compositions and methods for a scaffold coated with a primer coating and a mineral coating. Also provided is a composition for a scaffold having a mineral coating similar to bone.
Tissue Regeneration Systems, Inc.



Scaffold topics:
  • Nucleotide
  • Recombinant
  • Polynucleotide
  • Amino Acid
  • Biodegradable
  • Encapsulation
  • Surfactant
  • Enhancement
  • Monoclonal Antibody
  • Polypeptide
  • Immunogenic
  • Amino Acid Sequence
  • Monoclonal
  • Interleukin 2
  • Immune Disease


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