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Roti patents



      
           
This page is updated frequently with new Roti-related patent applications. Subscribe to the Roti RSS feed to automatically get the update: related Roti RSS feeds. RSS updates for this page: Roti RSS RSS


Method of implanting an aortic stent

Method of implanting an aortic stent

Date/App# patent app List of recent Roti-related patents
01/22/15
20150025616
 Method and  treating a carotid artery patent thumbnailMethod and treating a carotid artery
One disclosed embodiment comprises a method for treating lesions in the carotid artery of a mammalian body. The method comprises transcervical access and blocking of blood flow through the common carotid artery (with or without blocking of blood flow through the external carotid artery), shunting blood from the internal carotid artery and treating the lesion in the carotid artery..
Silk Road Medical, Inc.
01/15/15
20150018942
 Method of implanting an aortic stent patent thumbnailMethod of implanting an aortic stent
A method of implanting an aortic stent comprising steps of: putting a main tube on a metal guide wire; moving the main tube along the metal guide wire to the descending aorta, the main tube is constrained by a first cover, and first and second tube bifurcations are branched from the main section; removing the first cover; inserting a second and third metal guide wire through the first tube bifurcation into the ascending aorta and branchiocephalic artery respectively; a first and a second tube branch moving into the ascending aorta and the branchiocephalic artery respectively; inserting a fourth and fifth metal guide wire through the first tube bifurcation into the ascending aorta and branchiocephalic artery respectively; a third and a fourth tube branch moving into left common carotid artery and the left subclavian artery respectively; removing a second cover constraining said tube branches.. .
01/15/15
20150017151
 Pharmaceutical formulations of xanthine or xanthine derivatives, and their use patent thumbnailPharmaceutical formulations of xanthine or xanthine derivatives, and their use
The present invention relates to pharmaceutical formulations comprising xanthine or xanthine derivatives, kits thereof, and methods for treating fibrotic diseases by local administration.. .
Imprimis Pharmaceuticals, Inc.
01/08/15
20150010615
 Supercritical guggul extracts and uses thereof patent thumbnailSupercritical guggul extracts and uses thereof
The subject invention pertains to supercritical carbon dioxide extracts of commiphora mukul resin (guggul), which can be modified or not modified by some ethanol addition; methods for their production; and methods of use, such as inhibiting hmg-coa reductase, inhibiting transformation of pre-adipocytes to adipocytes, inhibiting triglyceride storage, promoting insulin sensitivity in adipocytes, treatment of disorders (for example, hypercholesterolemia, hyperlipidemia, hyperglycemia, obesity, metabolic syndrome, cardiovascular disease, atherosclerotic heart disease, autoimmune disorder, insulin resistance, leptin resistance, arthritis, cell proliferation disorder, such as cancer and atherosclerosis; damaged skin, sores, cuts, rashes, bruises, dryness, burns, sunburn, radiation burn, and infection), and regulating or suppressing appetite.. .
Flavex Naturextrakte Gmbh
01/01/15
20150005645
 Detection of a leading stroke risk indicator patent thumbnailDetection of a leading stroke risk indicator
Embodiments of a system and method for detecting a leading stroke risk indicator using low-cost, non-contact visual computing methods are generally described herein. In some embodiments, a video camera is arranged to capture a video of a face of a subject to be evaluated for having a stroke risk indicator.
12/25/14
20140377365
 Sustained-release formulation of rotigotine patent thumbnailSustained-release formulation of rotigotine
Provided herein are methods and compositions for producing formulations systemic delivery of dopamine agonists via the oral inhalation route. Specifically, provided herein are methods and compositions for a formulation of rotigotine that is suitable for administration via oral inhalation.
Map Pharmaceuticals, Inc.
12/25/14
20140377189
 Pulmonary administration of rotigotine patent thumbnailPulmonary administration of rotigotine
Provided herein are methods and compositions for producing formulations systemic delivery of dopamine agonists via the oral inhalation route. Specifically, provided herein are methods and compositions for a stable solution formulation of rotigotine that is suitable for administration via oral inhalation.
Map Pharmaceuticals, Inc.
12/25/14
20140376687
 Systems for characterizing atherosclerotic plaque and methods of using same patent thumbnailSystems for characterizing atherosclerotic plaque and methods of using same
The present technology relates generally to systems for characterizing atherosclerotic plaque, such as a spectral ct system, and methods of using same.. .
University Of Washington Through Its Center For Commercialization
12/18/14
20140371653
 Methods and systems for establishing retrograde carotid arterial blood flow patent thumbnailMethods and systems for establishing retrograde carotid arterial blood flow
Interventional procedures on the carotid arteries are performed through a transcervical access while retrograde blood flow is established from the internal carotid artery to a venous or external location. A system for use in accessing and treating a carotid artery includes an arterial access device, a shunt fluidly connected to the arterial access device, and a flow control assembly coupled to the shunt and adapted to regulate blood flow through the shunt between at least a first blood flow state and at least a second blood flow state.
Silk Road Medical, Inc.
12/18/14
20140371594
 Estimation and display for vector doppler imaging using plane wave transmissions patent thumbnailEstimation and display for vector doppler imaging using plane wave transmissions
Vector doppler imaging (vdi) improves on conventional color doppler imaging (cdi) by giving speed and direction of blood flow at each pixel of a display generated by a computing system. Multiple angles of plane wave transmissions (pwt) via an ultrasound transducer conveniently give projected doppler measurements over a wide field of view, providing enough angular diversity to identify velocity vectors in a short time window while capturing transitory flow dynamics.
Verasonics, Inc.
12/18/14
20140371593

Ultrasound diagnostic device and controlling ultrasound diagnostic device


An ultrasound diagnostic device for measuring a carotid artery wall property includes a transmission-reception processor, a transverse cross-sectional image generator, a transverse cross-sectional image selector, and a relative angle calculator. The transmission-reception processor performs transmission and reception processing of ultrasound with respect to the carotid artery.
Konica Minolta, Inc.
12/18/14
20140371089

Method for diganosing atherosclerotic plaques by measurement of cd36


The present invention relates to diagnosis, classification and monitoring of atherosclerotic plaques in an individual using measurement of the concentration of cd36 in a body fluid and/or the plaque as such. The present invention also relates to diagnosing the burden of atherosclerotic plaques in an individual.
12/11/14
20140364897

Methods and devices for embolic protection


An aortic flow diverter or filter is described that diverts particles away from the carotid vessels and right subclavian artery. The diverter includes a stent-like portion formed from a plurality of braided or woven wires that can radially self-expand.
12/11/14
20140363394

Formulation having mobilizing activity


The present innovation relates to a novel formulation capable of increasing the amount of stem cells and progenitor cells in circulation in the peripheral blood of a mammal; the formulation is characterized in that it contains defibrotide in combination with at least one haematopoietic factor having the capacity to mobilize haematopoietic progenitors, preferably g-csf. In one embodiment, the formulation includes two separately administrable formulations, one containing a haematopoietic factor having the capacity to mobilize haematopoietic progenitors and the other containing defibrotide.
11/27/14
20140350401

Carotid body ablation via directed energy


Methods and devices for assessing, and treating patients having sympathetically mediated disease, involving augmented peripheral chemoreflex and heightened sympathetic tone by reducing chemosensor input to the nervous system via carotid body ablation.. .
11/27/14
20140350021

Methods of use of inhibitors of phosphodiesterases and modulators of nitric oxide, reactive oxygen species, and metalloproteinases in the treatment of peyronie's disease, arteriosclerosis and other fibrotic diseases


The present methods and compositions are of use for treatment of conditions involving fibrosis, such as peyronie's disease plaque, penile corporal fibrosis, penile veno-occlusive dysfunction, dupuytren's disease nodules, vaginal fibrosis, clitoral fibrosis, female sexual arousal disorder, abnormal wound healing, keloid formation, general fibrosis of the kidney, bladder, prostate, skin, liver, lung, heart, intestines or any other localized or generalized fibrotic condition, vascular fibrosis, arterial intima hyperplasia, atherosclerosis, arteriosclerosis, restenosis, cardiac hypertrophy, hypertension or any condition characterized by excessive fibroblast or smooth muscle cell proliferation or deposition of collagen and extracellular matrix in the blood vessels and/or heart. In certain embodiments, the compositions may comprise a pde-4 inhibitor, a pde-5 inhibitor, a compound that elevates cgmp and/or pkg, a stimulator of guanylyl cyclase and/or pkg, a combination of a compound that elevates cgmp, pkg or no with an antioxidant that decreases ros, or a compound that increases mmp activity..
11/27/14
20140349956

Materials and methods for detecting and/or predicting necrotizing enterocolitis in infants


The subject invention pertains to materials and methods for diagnosing and/or predicting pathologic infant conditions. A method of the invention comprises obtaining a biological sample from an infant and analyzing the sample to detect at least one protein biomarker of necrotizing enterocolitis (nec), wherein a patient is diagnosed with nec or determined to have a likelihood of developing nec following detection of the biomarker.
11/27/14
20140349926

Formulations for the treatment of diabetes


Disclosed is a formulation for parenteral administration comprising insulin that comprises a ph memory between 1 to 4 or between 6 to 8 and an aprotic polar solvent, wherein the insulin is solubilized in the aprotic polar solvent, wherein the solubilized insulin comprises stable monomeric or dimeric forms of insulin or mixtures thereof, and wherein the water content of the formulation is equal to or less than 15% w/v.. .
11/20/14
20140343641

Methods and devices for non-invasive cerebral and systemic cooling


Methods for cerebral cooling are described. Cooling assemblies include elongate tubular members, a reservoir containing a pressurized fluid, and a manifold connecting the reservoir and elongate tubular members.
11/20/14
20140341999

Antitubercular composition and producing same


The invention relates to the field of pharmaceutics and medicine and concerns a medicinal composition of antitubercular preparations with a phospholipid transport system, the composition consisting of a fatty acid salt, phosphatidylcholine of vegetative origin (73-97%), maltose and an antitubercular agent selected from rifamycin, protionamide, rifabutin and rifapentine, and a method for producing the composition.. .
11/20/14
20140340675

Discrimination method and apparatus of cardiac tissue using raman scattering


A method and an apparatus for discriminating a cardiac tissue using raman scattering are provided which enable a noninvasive discrimination of the cardiac tissue to be accurately performed. The discrimination method includes: a step of irradiating a sample containing a cardiac tissue with excitation light; a step of detecting raman scattering light from the sample; an analysis step of analyzing the detected raman scattering light by a multivariate analysis using as an index, raman scattering spectra which are specific to at least a living myocardial tissue, a necrotic myocardial tissue, a granulation tissue and a fibrotic tissue, respectively; and a step of discriminating the cardiac tissue in accordance with analysis results obtained in the analysis step..
11/13/14
20140336690

Occluding catheter and dynamic prevention of stroke


A system for use in prevention of stroke is provided that has a shaft that carries an occluding balloon. The occluding balloon is inflated to occlude blood flow through at least one of a right carotid artery and a left carotid artery.
11/13/14
20140336139

Topical application of ivermectin for the treatment of dermatological conditions/afflictions


Dermatological conditions/afflictions such as rosacea, common acne, seborrheic dermatitis, perioral dermatitis, acneform rashes, transient acantholytic dermatosis, and acne necrotica miliaris, most notably rosacea, are treated by topically applying onto the affected skin area of an individual in need of such treatment, a topical pharmaceutical composition which comprises a thus effective amount of ivermectin.. .
11/13/14
20140336113

Compositions and methods for treating and preventing hyperlipidemia, fatty liver, atherosclerosis and other disorders associated with metabolic syndrome


The present invention relates to compositions and methods for treating diseases associated with dyslipidemia, including hypercholesterolemia, hypertriglyceridemia, steatohepatitis, atherosclerosis, obesity, hyperglycemia, metabolic syndrome, and related aspects of and conditions associated with metabolic syndrome. The compositions and methods disclosed herein are useful for regulating the lipid balance (lipid homeostasis) in a subject.
11/06/14
20140329260

Method of diagnosis of fibrotic diseases


The present invention relates to a new diagnosis method in the field of hepatology, combining measurement of serum markers and of liver elasticity.. .
11/06/14
20140328763

Bioactive amphiphilic polymer stabilized nanoparticles with enhanced stability and activity


The present invention relates to nanoparticle compositions and treatment of cardiovascular disease using nanoparticles to target class a and b scavenger receptors. This invention further relates to methods of detecting cells that express scavenger receptors, detecting atherosclerotic lesions, and targeting bioactive amphiphilic macromolecules to cells that express scavenger receptors..
10/30/14
20140322190

Pharmaceutical compositions and methods for digesting atherosclerotic plaques


Disclosed are pharmaceutical compositions and methods for digesting atherosclerotic plaques in a patient in need thereof. The compositions include and the methods utilize a mixture of collagenases for digesting plaques and optionally may include or utilize additional agents such as cyclodextrins, chelating agents, and tissue plasminogen activator..
10/30/14
20140319423

Sulfolane mixtures as ambient aprotic polar solvents


An improved solvent containing sulfolane and at least one dialkyl sulfone, preferably dimethyl sulfone, wherein the improved solvent is a liquid at room temperature and can be used for reaction media and electrochemistry.. .
10/16/14
20140309581

Method for treating chronic wounds with an extracellular polymeric substance solvating system


Chronic wounds may be treated by debriding necrotic and other devitalized tissue from the wound, and applying to the wound an extracellular polymeric substance solvating system comprising a metal ion sequestering agent, surfactant and buffering agent. The solvating system disrupts biofilms which may be present in the wound and aids or enables the resumption of normal healing..
10/16/14
20140309234

Small molecule anti-fibrotic compounds and uses thereof


The present invention provides methods for treating fibrotic diseases by administering a compound having the general structural formula (i). .
10/09/14
20140303140

Novel compounds and pharmaceutical compositions thereof for the treatment of inflammatory disorders


Wherein r1a, r1b, r2, r4, r5, r6a, r6b, r7, r8, w, x, cy, and the subscript a are as defined herein. The present invention relates to compounds inhibiting autotaxin (npp2 or enpp2), methods for their production, pharmaceutical compositions comprising the same, and methods of treatment using the same, for the prophylaxis and/or treatment of diseases involving fibrotic diseases, proliferative diseases, inflammatory diseases, autoimmune diseases, respiratory diseases, cardiovascular diseases, neurodegenerative diseases, dermatological disorders, and/or abnormal angiogenesis associated diseases by administering the compound of the invention..
10/09/14
20140302128

Biological oil composition, formulations comprising the oil composition, and use thereof to prevent or treat cardiovascular disease


This invention relates to a biological oil composition, preferably obtained from a copepod, most preferably the copepod calanus finmarchicus and the use thereof to prevent or treat formation of atherosclerotic plaques and hence development of coronary heart disease. The composition comprises the same marine n-3 polyunsaturated fatty acids (pufas) generally regarded as being responsible for the anti-atherosclerotic effect of marine oils, namely epa (c20:5n-3 eicosapentaenoic acid) and dha (c22:6n-3 docosahexaenoic acid).
10/02/14
20140296889

Devices and methods for percutaneous endarterectomy


Devices and methods are provided for percutaneously treating atherosclerotic plaques within blood vessels. Atherosclerotic plaques cause significant morbidity and mortality by narrowing the arteries, which adversely affects blood flow, and by acting as a source for thrombi and emboli thus causing acute organ ischemia.
10/02/14
20140296769

Methods and systems for establishing retrograde carotid arterial blood flow


Devices and methods establish and facilitate retrograde or reverse flow blood circulation in the region of the carotid artery bifurcation in order to limit or prevent the release of emboli into the cerebral vasculature such as into the internal carotid artery. The methods are particularly useful for interventional procedures performed through a transcervical approach or transfemoral into the common carotid artery..
10/02/14
20140296217

Medicaments for the treatment or prevention of fibrotic diseases


R1 to r5 and x are defined as in claim 1, the isomers and the salts thereof, particularly the physiologically acceptable salts thereof, as a medicament for the prevention or treatment of specific fibrotic diseases.. .
09/25/14
20140289907

Tomato spotted wilt virus and/or impatiens necrotic spot virus resistance in cultivated lettuce


The invention relates to a lettuce plant (lactuca sativa l.), which may comprise a genetic determinant, which confers resistance to tomato spotted wilt virus (tswv) and/or impatiens necrotic spot virus (insv), and which is as found in plants grown from seeds of which a representative sample was deposited under ncimb accession number ncimb 42023. The invention further provides seeds, progeny, propagation material and food products from the plant..
09/25/14
20140288587

Carotid sheath with entry and tracking rapid exchange dilators and use


Dilators and sheaths for use in minimally invasive vascular therapy are disclosed. In some embodiments, the dilators include a slot that accesses a guidewire lumen within the dilator.
09/25/14
20140288136

Methods and uses of cytochrome p450 inhibitors


Methods are provided for treating or preventing chronic obstructive pulmonary diseases such as emphysema, and fibrotic diseases including heart, liver, kidney and vascular diseases, by administering to a subject a pharmaceutical composition comprising a compound that inhibits cytochrome p450ra or cyp26.. .
09/25/14
20140288015

Methods and devices for affecting nerve function


Various methods and devices are described for affecting nerve function in the carotid body, renal nerves, and other nerves. Syringes, endovascular catheters, drug-eluting balloons, drug-eluting stents, and agent delivery patches are used to deliver a neuromodulatory agent to one or more nerves in order to treat a disease state..


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This listing is a sample listing of patent applications related to Roti for is only meant as a recent sample of applications filed, not a comprehensive history. There may be associated servicemarks and trademarks related to these patents. Please check with patent attorney if you need further assistance or plan to use for business purposes. This patent data is also published to the public by the USPTO and available for free on their website. Note that there may be alternative spellings for Roti with additional patents listed. Browse our RSS directory or Search for other possible listings.
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