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Rheumatoid Arthritis

Rheumatoid Arthritis-related patent applications - as published by the U.S. Patent and Trademark Office (USPTO).


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Biomarkers for rheumatoid arthritis and usage thereof
Bgi Shenzhen
August 10, 2017 - N°20170226565

Biomarkers and methods for predicting risk of a disease in particular ra are provided. Sequences of dna are obtained. The dna may be extracted from a sample that is collected from a subject. A relative abundance of a biomarker is then calculated based on the sequences of the dna. The biomarker comprises a dna sequence in a genome of lactobacillus ...
Phospholipid-containing marine extracts for treatment of cardiovascular diseases
Neptune Technologies & Bioressources, Inc.
August 10, 2017 - N°20170224742

The present invention relates to a method of treatment and/or prevention of cardiovascular disease, rheumatoid arthritis, skin cancer, premenstrual syndrome, diabetes and transdermal transport enhancement. The method comprises the administration of a therapeutically effective amount of krill and/or marine oil to a patient. The present invention also relates to a composition for the treatment and/or prevention of ...
Methods and compositions for modulating th-gm cell function
National University Of Singapore
August 03, 2017 - N°20170219581

Disclosed herein is a t-helper cell (“th-gm” cell) that is regulated by il-7/stat5 and which secrete gm-csf/il-3. Also disclosed are methods and compositions for modulating th-gm function for the treatment of, e. G., inflammatory disorders. Diagnostic and prognostic methods for specifically identifying th-gm-mediated inflammatory disorders (e. G., rheumatoid arthritis), as distinct from and/or ...
Rheumatoid Arthritis Patent Pack
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Rheumatoid Arthritis Patent Applications
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Methods of using il-1beta compounds
Novartis Ag
August 03, 2017 - N°20170218063

This invention relates to methods employing il-1β-ligand/il-1 receptor disrupting compounds (herein referred to as “il-1beta compounds”); such as small molecular compounds disrupting il-1β ligand-il-1 receptor interaction, il-1β antibodies or il-1 receptor antibodies, e. G. Il-1β binding molecules as described herein, e. G. Antibodies disclosed herein, ...
Anti-gm-csf antibodies
Morphosys Ag
August 03, 2017 - N°20170218061

The present invention provides recombinant antigen-binding regions, antibodies and functional fragments thereof that are specific for gm-csf, which plays an integral role in various disorders or conditions. These antibodies, accordingly, can be used to treat, for example, inflammatory diseases such as rheumatoid arthritis. Antibodies of the invention also can be used in the diagnostics field, as well as for further ...
Methods for treating thrombosis using chimeric and humanized anti-histone antibodies
Immunomedics, Inc.
August 03, 2017 - N°20170218059

The present invention concerns chimeric or humanized antibodies or antigen-binding fragments thereof that comprise specific cdr sequences, disclosed herein. Preferably, the antibodies or fragments comprise specific heavy and light chain variable region sequences disclosed herein. More preferably, the antibodies or fragments also comprise specific constant region sequences, such as those associated with the ng1m1,2 or km3 allotypes. The antibodies ...
Rheumatoid Arthritis Patent Pack
Download 109+ patent application PDFs
Rheumatoid Arthritis Patent Applications
Download 109+ Rheumatoid Arthritis-related PDFs
For professional research & prior art discovery
inventor
  • 109+ full patent PDF documents of Rheumatoid Arthritis-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
N-(4-hydroxy-4-methyl-cyclohexyl)-4-phenyl-benzenesulfonamides and n-(4- hydroxy-4-methyl-cyclohexyl)-4-(2-pyridyl)benzenesulfonamides and ...
Pimco 2664 Limited
August 03, 2017 - N°20170217881

The present invention pertains generally to the field of therapeutic compounds. More specifically the present invention pertains to certain substituted n-(4-hydroxy-4-methyl-cyclohexyl)-4-phenyl-benzenesulfonamide and n-(4-hydroxy-4-methyl-cyclohexyl)-4-(2-pyridyl)benzenesulfonamide compounds (collectively referred to herein as hmc compounds) that are useful, for example, in the treatment of disorders (e. G., diseases) including, inflammation and/or joint destruction ...
Composition containing smad protein for treatment of autoimmune diseases, a fusion protein comprising smad protein, ...
Pimco 2664 Limited
July 27, 2017 - N°20170210783

The present invention relates to a composition and a fusion protein for prevention or treatment of autoimmune diseases, which contain a smad protein, and provides a method for prevention or treatment of autoimmune diseases, including lupus nephritis and rheumatoid arthritis.
Method for preparing dendritic cells with increased specific gene expression, and composition for treating or ...
Jw Creagene Inc.
July 27, 2017 - N°20170209557

The present invention relates to a method for generating semi-mature dendritic cells by treating immature dendritic cells with the auto-antigen, cytokine, and pge2 as a target for the treatment of autoimmune diseases, particularly rheumatoid arthritis, in which the levels of nr4a2 and/or ubash3b at gene or protein are increased more than 2-fold compared to the immature dendritic ...
Method for treating rheumatoid arthritis
Queen Mary University Of London
July 20, 2017 - N°20170205408

The present invention provides a method for determining whether a rheumatoid arthritis (ra) patient is susceptible to treatment with a b cell targeted therapy, which method comprises the step of analysing b cells and/or germinal centre-like structures (gc-ls) in a synovial tissue sample from the patient; wherein a patient whose synovial tissue sample is b cell rich and/or ...
Tcr/mhcii-collagen interaction inhibitors useful for the treatment of rheumatoid arthritis
UniversitÀ Cattolica Del Sacro Cuore
July 20, 2017 - N°20170204059

The t cells specific to human collagen type ii, one of the possible autoantigens, have a crucial role in the development of rheumatoid arthritis in the context of hla-dr4. The protein-protein interactions between the t cell receptor (tcr) and the type ii collagen linked to the allele mhc of class ii hla-dr4 may thus represent the target for the development ...
Anti-il-17a antibodies and their use in treating autoimmune and inflammatory disorders
Novartis Ag
July 13, 2017 - N°20170198035

The present disclosure relates to antibodies and proteins comprising an antigen-binding portion thereof that specifically bind to the pro-inflammatory cytokine il-17 a. The disclosure more specifically relates to specific antibodies and proteins that are il-17 a antagonists (inhibit the activities of il-17 a and il-17 af) and are capable of inhibiting il-17 a induced cytokine production in in vitro assays, ...
Antibodies that bind and block triggering receptor expressed on myeloid cells-1 (trem-1)
Novo Nordisk A/s
July 06, 2017 - N°20170190775

The invention relates to antibodies that are capable of specifically binding trem-1 and preventing the activation of trem-1, a protein expressed on monocytes, macrophages and neutrophils. Such antibodies find utility in the treatment of individuals with an inflammatory disease, such as rheumatoid arthritis and inflammatory bowel disease.
Rheumatoid Arthritis Patent Pack
Download 109+ patent application PDFs
Rheumatoid Arthritis Patent Applications
Download 109+ Rheumatoid Arthritis-related PDFs
For professional research & prior art discovery
inventor
  • 109+ full patent PDF documents of Rheumatoid Arthritis-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
Circulating mirnas as biomarkers of therapy effectiveness in rheumatoid arthritis patients treated with anti-tnf alpha
FundaciÓn Para La InvestigaciÓn BiomÉdica De CÓrdoba
June 29, 2017 - N°20170183734

The present invention relates to a method of predicting response of a human subject to anti-tnfa therapy, and preferably wherein the subject is suffering from rheumatoid arthritis.
Corticosteroids for the treatment of joint pain
Flexion Therapeutics, Inc.
June 29, 2017 - N°20170182068

Corticosteroid microparticle formulations are provided for use for treating pain, including pain caused by inflammatory diseases such as osteoarthritis or rheumatoid arthritis, and for slowing, arresting or reversing structural damage to tissues caused by an inflammatory disease, for example damage to articular and/or peri-articular tissues caused by osteoarthritis or rheumatoid arthritis. Corticosteroid microparticle formulations are administered locally as a ...
Quinolinyl modulators of roryt
Flexion Therapeutics, Inc.
June 29, 2017 - N°20170182056

The invention also comprises a method of treating or ameliorating a syndrome, disorder or disease, wherein said syndrome, disorder or disease is rheumatoid arthritis or psoriasis. The invention also comprises a method of modulating rorγt activity in a mammal by administration of a therapeutically effective amount of at least one compound of claim 1.
Modulators of gtpases and their use
Stc.unm
June 29, 2017 - N°20170182002

The present invention relates to molecules which function as modulators (i. E., inhibitors and agonists) of the ras-homologous (rho) family of small gtpases (e. G. Rac, cdc42 and rho gtpases) and their use to treat diseases, including cancers (including solid tumors-medulloblastoma, ovarian, breast, head and neck, testicular, prostate among others and hematologic malignancies-b cell lymphoma, where these gtpases are overexpressed ...
Pyrrolopyrimidine compounds, use as inhibitors of the kinase lrrk2, and methods for preparation thereof
Southern Research Institute
June 22, 2017 - N°20170174694

The present disclosure is concerned with certain pyrrolopyrimidine compounds that are capable of inhibiting certain protein kinases, and especially the leucine-rich repeat kinase 2 (lrrk2) protein. Compounds of the present disclosure can be used to treat a number of disorders caused by or associated with abnormal lrrk2 kinase activity. Compounds of the present disclosure can be used to treat disorders including ...
Protease inhibitors
Southern Research Institute
June 15, 2017 - N°20170166538

Or a pharmaceutically acceptable salt, n-oxide or hydrate thereof, have utility in the treatment of disorders characterized by inappropriate expression or activation of cathepsin k, such as osteoporosis, osteoarthritis, rheumatoid arthritis or bone metastases:
Novel bisaminoquinoline compounds, pharmaceutical compositions prepared therefrom and their use
The Trustees Of The University Of Pennsylvania
June 15, 2017 - N°20170166530

The present invention relates to novel bisaminoquinoline compounds, pharmaceutical compositions comprising these novel compounds and methods for inhibiting autophagy in biological systems. Methods of treating cancer in patients in need using compounds and/or compositions according to the present invention alone or in combination with at least one additional anticancer agent represent additional aspects of the invention. Methods of treating ...
Binding inhibitor between tctp dimer type ige-dependent histamine releasing factor and receptor thereof, and use ...
Ewha University - Industry Collaboration Foundation
June 08, 2017 - N°20170158761

The present invention relates to a receptor-binding domain of an ige-dependent histamine releasing factor (hrf), and a use thereof, and more specifically, ascertains, as an hrf structual region, and a fl domain and an h2 domain which bind to a receptor of hrf existing in a cell membrane, ascertains the c-terminus domain of the hrf, and ascertains that a material ...
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