Images List Premium Download Classic

Restenosis

Restenosis-related patent applications - as published by the U.S. Patent and Trademark Office (USPTO).


loading
Inhibitors of trka kinase
Gvk Biosciences Private Limited
January 11, 2018 - N°20180009781

The present invention is directed to the compounds of formula i which are inhibitors of tropomyosin-related kinase a (trka): formula (i) or steroisomers, tautomers or a pharmaceutically acceptable salts, metabolites, isotopes, solvates or prodrugs thereof, wherein, ra, rb, rc, rd, r1, r2, l and het-ar are as defined herein. These compounds can be used for the preventive and/or therapeutic ...
Modulators of the prostacyclin (pgi2) receptor useful for the treatment of disorders related thereto
Arena Pharmaceuticals, Inc.
December 21, 2017 - N°20170360730

The present invention relates to amide derivatives of formula (xiiia) and pharmaceutical compositions thereof that modulate the activity of the pgi2 receptor. Compounds of the present invention and pharmaceutical compositions thereof are directed to methods useful in the treatment of: pulmonary arterial hypertension (pah); idiopathic pah; familial pah; pah associated with a collagen vascular disease, a congenital heart disease, portal ...
Compounds and methods for modulating vascular injury
The Regents Of The University Of California
November 09, 2017 - N°20170319529

Methods of modulating healing response to vascular injury and/or vascular scarring in a subject are provided. As such, aspects of the disclosure relate to the use of pro-resolving lipid mediators to modulate inflammation and/or restenosis of a vascular wall. Another aspect of the disclosure relates to the use of pro-resolving lipid mediators to modulate a biological activity of ...
Restenosis Patent Pack
Download + patent application PDFs
Restenosis Patent Applications
Download + Restenosis-related PDFs
For professional research & prior art discovery
inventor
  • + full patent PDF documents of Restenosis-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
Plasma modified medical devices and methods
October 19, 2017 - N°20170296708

Coatings, devices and methods are provided, wherein the contacting surface of a medical device with at least one contacting surface for contacting a bodily fluid or tissue, wherein long-lasting and durable bioactive agents or functional groups are deposited on the contacting surface through a unique two-step plasma coating process with deposition of a thin layer of plasma coating using a ...
Detection of restensosis risk in patients receiving a stent
October 12, 2017 - N°20170292965

Provided is a method of selecting a stent for implantation in the circulatory system of a human being. The method comprises obtaining a blood sample from a patient who requires implantation of a stent and testing said blood sample to determine a platelet coagulability level. The determined platelet coagulability level of said blood sample is compared with a threshold level ...
Drug eluting device
Rontis Hellas S.a.
August 31, 2017 - N°20170246354

The present invention relates to a drug eluting device for preventing and treating restenosis and neointimal formation after vascular procedures and/or implantation of implants comprising an implantable or non-implantable device, such as stent, balloon or graft containing an effective amount of at least one retinoid receptors ligand as active ingredient and a coating system.
Restenosis Patent Pack
Download + patent application PDFs
Restenosis Patent Applications
Download + Restenosis-related PDFs
For professional research & prior art discovery
inventor
  • + full patent PDF documents of Restenosis-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
Reversible immobilization and/or controlled relase of nucleic acid containing nanoparticles by (biodegradable) polymer coatings
Curevac Ag
August 24, 2017 - N°20170239372

The present invention relates to nanoparticles comprising nucleic acids coated with a (biodegradable) polymer for reversible immobilization and/or controlled release of the nucleic acid comprising nanoparticles. Furthermore, the present invention is directed to medical or diagnostic devices, particularly stents and implants coated by a (biodegradable) polymer with the nucleic acid comprising nanoparticles for reversible immobilization and/or controlled release. ...
Methods of use of inhibitors of phosphodiesterases and modulators of nitric oxide, reactive oxygen species, ...
Los Angeles Biomedical Research Institute At Harbor- Ucla Medical Center
August 24, 2017 - N°20170239257

The present methods and compositions are of use for treatment of conditions involving fibrosis, such as peyronie's disease plaque, penile corporal fibrosis, penile veno-occlusive dysfunction, dupuytren's disease nodules, vaginal fibrosis, clitoral fibrosis, female sexual arousal disorder, abnormal wound healing, keloid formation, general fibrosis of the kidney, bladder, prostate, skin, liver, lung, heart, intestines or any other localized or generalized fibrotic ...
Cyclic polypeptides for the treatment of heart failure
August 17, 2017 - N°20170233443

Or an amide, an ester or a salt thereof, or a bioconjugate thereof, wherein x1, x3, x4, x7, x8, x9, x10, x11, x12 and x13 are defined herein. The polypeptides are agonist of the apj receptor. The invention also relates to a method for manufacturing the polypeptides of the invention or bioconjugates thereof, and their therapeutic uses such as treatment ...
Apparatus and method for treatment of in-stent restenosis
Boston Scientific Scimed, Inc.
August 17, 2017 - N°20170231694

A catheter and catheter system can use energy tailored for remodeling and/or removal of target material proximate to a body lumen, often of stenotic material or tissue in the luminal wall of a blood vessel of a patient. An elongate flexible catheter body with a radially expendable structure may have a plurality of electrodes or other electrosurgical energy delivery ...
Scaffold with drug coating for preventing and treating restenosis and preparation method thereof
Xiyuan Hospital Of China Academy Of Chinese Medical Sciences
August 03, 2017 - N°20170216497

Disclosed is a stent with a drug coating for preventing and treating restenosis, comprising, a stent and a drug coating covering the surface of the stent. The active ingredients in the drug coating are guaiane sesquiterpene compounds p1, p2 and p3. P1 is zedoalactone b, p2 is a stereoisomer of p1, and p3 is zedoarondiol. Compared with an existing sirolimus ...
Compounds and methods for modulating vascular injury
The Brigham And Women's Hospital, Inc.
August 03, 2017 - N°20170216238

Methods of modulating healing response to vascular injury and/or vascular scarring in a subject are provided. As such, aspects of the disclosure relate to the use of pro-resolving lipid mediators to modulate inflammation and/or restenosis of a vascular wall. Another aspect of the disclosure relates to the use of pro-resolving lipid mediators to modulate a biological activity of ...
Small molecule inhibitors of stat3 with anti-tumor activity
University Of Central Florida Research Foundation.
July 20, 2017 - N°20170202795

The present invention concerns compounds, compositions containing these compounds, and methods of using these compounds and compositions as inhibitors of stat3 signaling, stat3 dimerization, stat3-dna binding, stat5-dna binding, and/or aberrant cell growth in vitro or in vivo, e. G., as anti-cancer agents for treatment of cancer, such as breast cancer. The compounds of the invention include, but ...
Restenosis Patent Pack
Download + patent application PDFs
Restenosis Patent Applications
Download + Restenosis-related PDFs
For professional research & prior art discovery
inventor
  • + full patent PDF documents of Restenosis-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
Stent for inhibiting restenosis and stimulating reendothelialization prepared by femtosecond laser processing and method of ...
Jeonnam Technopark
June 29, 2017 - N°20170182227

Provided are a stent in which a surface of a stent strut is treated by femtosecond laser radiation and is modified by a natural polymer and a method of preparing the stent. The stent and the preparing method may inhibit restenosis and stimulate reendothelialization.
Drug-eluting medical device
Invatec Technology Center Gmbh
June 22, 2017 - N°20170173220

The present invention relates to a drug-eluting medical device, in particular a balloon for angioplasty catheters with drug elution to prevent the restenosis of the vessel subjected to angioplasty. More particularly, the present invention relates to a catheter balloon completely or partially coated with paclitaxel in hydrated crystalline form or in hydrated solvated crystalline form, having an immediate release and ...
Trka kinase inhibitors, compositions and methods thereof
Merck Sharp & Dohme Corp.
June 08, 2017 - N°20170158698

The present invention is directed to substituted five membered heteroaryl benzamide compounds of formula (i) (formula (i)) which are tropomyosin-related kinase (trk) family protein kinase inhibitors, and hence are useful in the treatment of pain, inflammation, cancer, restenosis, atherosclerosis, psoriasis, thrombosis, a disease, disorder, injury, or malfunction relating to dysmyelination or demyelination or a disease or disorder associated with abnormal ...
Novel crystalline form of 5-chloro-n-(methyl)thiophene-2-carboxamide methanesulfonate and pharmaceutical composition comprising same
Legochem Biosciences,inc.
June 01, 2017 - N°20170152251

The present invention relates to a novel crystalline form of 5-chloro-n-({(5s)-2-oxo-3-[4-(5,6-dihydro-4h-[1,2,4]triazin-1-yl)phenyl]-1,3-oxazolidin-5-yl}methyl)thiophene-2-carboxamide methanesulfonate and a pharmaceutical composition containing the same. The novel crystalline form of a compound according to the present invention exhibits excellent stability even in high-temperature and humidity environments, and thus can be ...
Coating composition and medical device
May 25, 2017 - N°20170143663

A coating composition for drug-eluting medical devices, which enables a medical device to be delivered to a target tissue for the purpose of treating an affected blood vessel part such as restenosis, without easy separation of a drug from the medical device during the delivery process is provided. The coating composition for drug-eluting medical devices contains a water-insoluble drug and ...
Balloon angioplasty catheter coating to encourage vessel repair and further reduce restenosis
Angioscore, Inc.
May 18, 2017 - N°20170136219

A method for treating a target vascular portion of a subject including: providing an angioplasty balloon system including a balloon carrying a first therapeutic agent and a second therapeutic agent on a surface of the balloon, wherein the first therapeutic agent is an anti-proliferative or anti-mitotic agent and the second therapeutic agent is a drug that aids in vascular healing ...
Trka kinase inhibitors, compositions and methods thereof
Msd R & D (china) Co., Ltd.
April 27, 2017 - N°20170114071

The present invention is directed to six membered heteroaryl benzamide compounds of formula (i), which are tropomyosin-related kinase (trk) family protein pain, inflammation, cancer, restenosis, atherosclerosis, psoriasis, thrombosis, a disease, disorder, injury, or malfunction relating to dysmyelination or demyelination or a disease or disorder associated with abnormal activities of nerve growth factor (ngf) receptor trka.
Trka kinase inhibitors, compositions and methods thereof
Merck Sharp & Dohme Corp.
April 27, 2017 - N°20170114056

The present invention is directed to a bicyclic heteroaryl benzamide compounds of formula (i) which are tropomyosin-related kinase (trk) family protein kinase inhibitors, and hence are useful in the treatment of pain, inflammation, cancer, restenosis, atherosclerosis, psoriasis, thrombosis, a disease, disorder, injury, or malfunction relating to dysmyelination or demyelination or a disease or disorder associated with abnormal activities of nerve ...
Loading