This page is updated frequently with new Respiratory-related patent applications.
| Method of time-efficient 4d magnetic resonance imaging|
A method of operating a respiratory-guided magnetic resonance imaging system (10) with regard to triggering of magnetic resonance image acquisition, the magnetic resonance imaging system (10) being connectable to a respiration monitoring device (46) which is configured to provide an output signal (48) whose level represents a respiration state of the subject of interest (20), the method comprising a step (56) of generating an interleaved acquisition scheme for acquiring magnetic resonance images, a step (60) of adapting, in case of an occurrence of an irregularity in the breathing of the subject of interest (20) in the output signal (48) obtained by the respiration monitoring device (46) in the course of executing magnetic resonance image acquisition, at least one parameter of the interleaved acquisition scheme, wherein the at least one adapted parameter is at least one of a next respiration state of the subject of interest (20) to trigger on for acquiring at least one magnetic resonance image, a radio frequency pulse sequence-inherent idle time, and the chronological order of at least one slice of the plurality of slices to be imaged of at least the portion of the subject of interest (20), a step (62) of halting execution of magnetic resonance image acquisition, and a step (64) of resuming execution of magnetic resonance image acquisition pursuant to the interleaved acquisition scheme using the adapted parameter; a respiratory-guided magnetic resonance imaging system (10) having a control unit (26) that is configured to carry out steps (56-64) of an embodiment of the disclosed method; and a software module (44) for carrying out an embodiment of the disclosed method, wherein the method steps (56-64) to be conducted are converted into a program code that is implementable in a memory unit (30) and is executable by a processor unit (32) of the respiratory-guided magnetic resonance imaging system (10).. .
Koninklijke Philips N.v.
| System and magnetic resonance fingerprinting at high field strengths|
A system and method is provided for operating a high-field magnetic resonance (mr) system includes performing a series of data acquisition modules without respiratory gating. Each data acquisition module is formed of a steady-state free precession pulse sequence.
Case Western Reserve University
| Pulmonary system resistance training apparatus and methods|
A respiratory exerciser having a hollow body, where the hollow portion is in communication with a porous or non-porous material and with an opening that provides access for a user to breathe through the device.. .
| Respiratory syncytial virus vaccine|
Described is a vaccine against respiratory syncytial virus (rsv). More specifically, described is a recombinant subunit vaccine comprising the ectodomain of the rsv-encoded small hydrophobic (sh) protein.
| Semi-live respiratory syncytial virus vaccine|
The present invention relates to a semi-live respiratory syncytial virus (rsv) vaccine, which comprises a genome replication-deficient sendai virus (sev) vector expressing a chimeric rsv/sev f protein. Furthermore, the present invention relates to a method for the production of the genome replication-deficient sev vector of the present invention, and the use thereof in the treatment of rsv infections and rsv infection-related diseases..
| Vaccine compositions against porcine reproductive and respiratory syndrome and porcine circovirus associated diseases|
A fusion protein comprising an antigen-presenting cell (apc)-binding domain or a cd91 receptor-binding domain, a translocation peptide, a fusion antigen, an endoplasmic reticulum retention sequence, and optionally a nuclear export signal is disclosed. The fusion antigen comprises a porcine reproductive and respiratory syndrome virus (prrsv) orf7 antigen, a prrsv orf1b antigen, a prrsv orf6 antigen, and a prrsv orf5 antigen.
Reber Genetics Co., Ltd.
| No/he gas mixture with bactericidal action|
The invention relates to a gas composition containing nitrogen monoxide (no) and helium (he), which is administered by inhalation in order to prevent or treat at least a bacterial infection affecting all or some of the respiratory tract of a patient, especially the bronchial tree and the lungs.. .
Air Liquide Sante (international)
| Compounds having muscarinic receptor antagonist and beta2 adrenergic receptor agonist activity|
Compounds of formula i, defined herein, act both as muscarinic receptor antagonists and beta2 adrenergic receptor agonists and are useful for treating diseases of the respiratory tract.. .
Chiesi Farmaceutici S.p.a.
| Aminoester derivatives|
Compounds of formula (i) defined herein are both phosphodiesterase 4 (pde4) enzyme inhibitors and muscarinic m3 receptor antagonists and are useful for treating diseases of the respiratory tract.. .
Chiesi Farmaceutici S.p.a.
| Treatment of respiratory disorders using ror-gamma inhibitors|
The present patent application relates to treatment of a respiratory disorder using retinoid-related orphan receptor gamma t (ror-gamma) modulators. Particularly, the present patent application relates to treatment of a respiratory disorder using a rorγ inhibitor, wherein the rorγ inhibitor is administered by an inhalation route to a subject in need thereof..
Glenmark Pharmaceuticals S.a.
Optimised 4d cone beam computed tomography projection allocation
A method, and a system when implementing a method, of reducing artefacts in image creation in 4d cone beam computed tomography (4dcbct) images, the method comprising the steps of: (a) performing a 4dcbct scan of a target patient including a series of spaced apart projections through the target patient, with each projection having an associated estimated or measured respiratory state; (b) initially dividing the series of projections into a corresponding series of respiratory bins, with each respiratory bin having projections substantially from a portion of a cyclic respiratory state; and (c) optimising the projections at the bounds of each respiratory bin so as to improve an image quality measure of the images.. .
The University Of Sydney
Wearable device and system for stopping airway disorders including such a wearable device
A wearable device for detecting body characteristics and for use in an airways disorder alleviating system includes a device housing, a means for attaching the device housing to a body part of a sleeping individual, one or more sensors configured to detect body characteristics, and a communication unit configured to communicate at least one of information of body characteristics and a respiratory disorder event information indicating that a respiratory disorder event is ongoing or upcoming to an external device.. .
Nitetronic Holding Limited
Respiratory movement measuring device
There is provided a respiratory movement measurement apparatus that can obtain a respiratory movement signal for each region by dividing and setting a region to be evaluated in a simple manner with good reproducibility. The respiratory movement measurement apparatus emits a light flux to a body surface 32 of a subject 31, captures reflected light by a camera 35, and thereby measures a respiration rate of the subject, wherein a merkmal indicating a mark position is further set on the body surface of the subject, a mark having a reflectance different from that of the body surface is placed on the merkmal, the body surface is divided into a plurality of regions on an observed image by a dividing line passing through the mark, bright spot reflection for each of the divided regions is summed, and thereby a respiratory movement signal is obtained..
Handheld portable impulse oscillometer
A multitude of clinical research studies have validated the superiority of impulse oscillometry (ios) over spirometry because it is far more sensitive in the detection of pulmonary diseases and since it is effort-independent, it can be successfully used in children as young as six-months old. By miniaturizing the ios to be a hand-held and portable device, the present invention takes ios technology out of the exclusive environments of the research lab and specialty pulmonology office.
System and monitoring biological status through contactless sensing
A system and method for monitoring biological status through contactless sensing that includes a sensing device with at least one video imaging device; a sensor data processing unit, wherein the sensor processing unit when in a respiratory sensing mode is configured to extract a set of primary components of motion from image data from the video imaging device; a biological signal processor that when in a respiratory sensing mode is configured to identify at least one dominant component of motion and generate a respiratory signal; and a monitor system.. .
Wearless Tech Inc
Respiratory assistance device
A respiratory assistance device used by a patient having a breathing problem. Specifically, the respiratory assistance device includes a blower for taking in gas and sending out the gas into the respiratory tract of the patient, an upstream-side humidifier for humidifying the gas to be introduced into the blower on the upstream side of the blower, and a downstream-side humidifier for humidifying the gas sent out from the blower on the downstream side of the blower..
Metran Co., Ltd.
Improvements relating to respiratory masks
A sealing cushion (16) for a respiratory mask assembly (10) has a patient interface portion (18) having a resiliently deformable membrane (24) for engagement with a patient's face, and an aperture (26) formed therein for receiving a nasal and/or mouth region of a patient's face. An inner surface of the membrane has a plurality of projections (32, 34, 36, 38, 40).
Recombinant low virulence bovine herpesvirus-1 (bohv-1) vaccine vectors
The present disclosure teaches generally in the field of vaccination and disease control in cattle and bovine animals. A recombinant bovine herpesvirus 1 (bohv-1) vaccine vector is provided for efficient control of one or more bovine pathogens such as those associated with bovine respiratory disease complex, such as bovine viral diarrhea virus (bvdv), and which ameliorates disease conditions caused thereby.
Meat & Livestock Australia Limted
Methods of treating bacterial infections
Methods of treating or ameliorating a bacterial infection comprising administering a composition comprising a cyclic boronic acid ester compound i in combination with meropenem are disclosed herewith. In some embodiments, the bacterial infection is a lower respiratory tract infection..
Rempex Pharmaceuticals, Inc.
Tiotropium inhalation solution for nebulization
The present invention relates to a sterile pharmaceutical composition comprising tiotropium or a pharmaceutically acceptable salt thereof, for inhalation via nebulization to a subject (e.g. A human).
Glenmark Specialty S.a.
Monoterpenes for treating respiratory disorders, in particular bronchopulmonary disorders
The invention relates to the combined use of at least one monoterpene which can be applied systemically, in particular perorally, and at least one respiratory tract therapeutic agent which can be applied topically, in particular through inhalation, for the prophylactic and/or therapeutic treatment, in particular combination therapy and/or co-medication, of respiratory tract diseases, in particular bronchopulmonary diseases. Through the combined use of the systemic monoterpene with the topical, in particular inhaled respiratory tract therapeutic agent, the effect or efficiency of the topical or inhaled respiratory disease therapeutic agent can be increased significantly, in particular in a synergistic manner, on the one hand, and the required dosage thereof can be reduced significantly on the other hand, combined with the resulting advantages (e.g., avoidance or reduction of side effects)..
Maria Clementine Martin Klosterfrau Vertriebsgesel Lschaft Mbh
Methods and systems for determining a metabolic fuel type being metabolized
Methods and systems for determining a proportion of a metabolic fuel being metabolized are disclosed. A computer can receive concentration measurements of substances exhaled by a user during a time period.
University Of Alaska Fairbanks
Methods and systems for determining effectiveness of respiration in individuals
The present invention relates to systems and methods for comparing photoplethysmography (ppg) signals from an individual with signals from a secondary respiration sensor secured to the individual to determine whether effective respiration has occurred or whether the individual has apnea, hypopnea, or other respiratory distress.. .
Method and device for determining the proportion of molecular oxygen in a respiratory gas by means of sound
The invention relates to a method for determining the proportion of molecular oxygen in a respiratory gas, for example in lung function diagnostics, comprising the introduction of the respiratory gas into a measurement tube, transmitting a sound signal by means of a sound transmitter and receiving the sound signal by means of a sound receiver, defining a sound measurement zone by means of the sound transmitter and the sound receiver, determining the average molar mass of the respiratory gas by means of a sound propagation time measured over the measurement zone, and determination of the carbon dioxide content of the respiratory gas with a carbon dioxide gas sensor. The invention also relates to a device for performing the method..
Novel polypeptide and uses thereof
The present invention relates to a novel polypeptide having specific modifications compared to the natural polypeptide. The said novel polypeptide has improved binding characteristics.
U-protein Express B.v.
Respiratory therapy apparatus
respiratory therapy apparatus includes an oscillating expiratory therapy device (100) and pressure and flow sensors (20 and 21) in the patient inlet (7) connected to supply signals to a processor (24). The processor (24) includes artificial intelligence software to correlate the output signals with prescribed values and control a feedback device (26) that prompts the patient accordingly to adjust use of the device as necessary.
Smiths Medical International Limited
Method for increasing the bioavailability of inhaled compounds
The present invention relates to a compound comprising one or more peg moieties, wherein said compound is a therapeutic agent active for treating a respiratory disease. The present invention also relates to the use of a pegylated therapeutic agent for treating a respiratory disease.
Universite De Liege
Methods of treating neurological, metabolic, and other disorders using enantiopure deuterium-enriched pioglitazone
The invention provides enantiopure deuterium-enriched pioglitazone, pharmaceutical compositions, and methods of treating neurological disorders, cancer, respiratory disorders, metabolic disorders, and other disorders using enantiopure deuterium-enriched pioglitazone. A preferred aspect of the invention provides methods of treating alzheimer's disease, non-small cell lung cancer, hepatocellular carcinoma, and chronic obstructive pulmonary disease using enantiopure deuterium-enriched pioglitazone..
New use of aclidinium
The present disclosure provides aclidinium or any of its stereoisomers or mixture of stereoisomers, or a pharmaceutically acceptable salt or solvate thereof, for improving the quality of sleep in respiratory patients.. .
Breath pacing pacing the respiratory activity of a subject
To provide a breath pacing system and a corresponding method for pacing the respiratory activity of a subject that provide the possibility to adapt the output signal to the respiration characteristics of the subject automatically and effectively a breath pacing system (10) for pacing the respiratory activity of a subject and a respective method is proposed, comprising: an input unit (14) for generating or determining an input signal related to a respiration characteristic of a subject, a signal analyzing unit (16) provided to recognize a signal pattern within the input signal, and an output unit (12) for outputting output signals corresponding to a desired breathing sequence, wherein said output unit (12) is provided to be activated, upon a starting signal, to output a sequence of output signals comprising a signal pattern related to a previously recognized signal pattern.. .
Koninklijke Philips N.v.
Method and processing cardiac signals and deriving non-cardiac physiological informatoin
A system and a method are provided for deriving elctrocardiographic (ecg] signals from a subject. The system includes an ecg apparatus configured to acquire ecg signals from the subject through a plurality of ecg leads, wherein the plurality of ecg leads includes lead groups that are traditionally presumed to be orthogonal.
The General Hospital Corporation
Breath analysis system, device and method employing nanoparticle-based sensor
A system is provided that includes a portable measurement device for measuring acetone in a breath sample of a user. The measurement device comprises a housing, a user-direct breath input device for engaging in direct fluid communication with a respiratory tract of the user and receiving the breath sample from the respiratory tract, a flow path disposed within the housing, a nanoparticle-based sensor disposed in the housing in fluid communication with the flow path and at an intermediate location between the upstream end and the downstream end, and a flow control device disposed in the housing and in the flow path between the upstream end and the nanoparticle-based sensor that prevents flow of the breath sample in an upstream direction opposite the downstream direction..
Invoy Technologies, Llc
Contact-free physiological monitoring during simultaneous magnetic resonance imaging
Devices and methods to measure and visualize the cardiac and respiratory signal of a human or animal subject during a magnetic resonance imaging (mri) exam are described. This includes a video camera compatible with the mri scanner, a means of transferring the video data away from the mri scanner, a light source that illuminates the subject, and an algorithm that analyses the video stream and uses small image intensity changes and motion information to extract cardiac signal and respiratory signals of the subject.
The Board Of Trustees Of The Leland Stanford Junior University