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 System and  classifying respiratory and overall health status of an animal patent thumbnailSystem and classifying respiratory and overall health status of an animal
Systems and methods are provided for determining the respiratory and overall health status of an animal. The systems and methods utilize location data of individual animals to generate variables describing the behavior of the individual animals.
Precision Animal Solutions, Llc


 Human monoclonal antibodies against the middle east respiratory syndrome coronavirus (mers-cov) and engineered bispecific fusions with inhibitory peptides patent thumbnailHuman monoclonal antibodies against the middle east respiratory syndrome coronavirus (mers-cov) and engineered bispecific fusions with inhibitory peptides
The invention provides polypeptides (e.g., antibodies) and fusion proteins that target a epitope in the receptor binding domain (rbd) of the spike (s) glycoprotein of the middle east respiratory syndrome coronavirus (mers-cov). The polypeptides and fusion proteins can be used to treat and prevent mers-cov infection in mammals..
The University Of Hong Kong


 4'-vinyl substituted nucleoside derivatives as inhibitors of respiratory syncytial virus rna replication patent thumbnail4'-vinyl substituted nucleoside derivatives as inhibitors of respiratory syncytial virus rna replication
Wherein the variable substituents are as defined herein. The compounds of formula i and pharmaceutical compositions comprising compounds of formula i are useful for the treatment of diseases mediated by rsv..

 Azido nucleosides and nucleotide analogs patent thumbnailAzido nucleosides and nucleotide analogs
Disclosed herein are nucleosides, nucleotides and analogs thereof, pharmaceutical compositions that include one or more of nucleosides, nucleotides and analogs thereof, and methods of synthesizing the same. Also disclosed herein are methods of ameliorating and/or treating a disease and/or a condition, including an infection from a paramyxovirus and/or an orthomyxovirus, with a nucleoside, a nucleotide and an analog thereof.
Alios Biopharma, Inc.


 Compounds patent thumbnailCompounds
And to compositions comprising the same and to the use of the compounds and their compositions in treatment, for example in the treatment of inflammatory diseases, in particular respiratory inflammatory disease. The invention also extends to methods of making said compounds..

 New cyclohexylamine derivatives having ß2 adrenergic agonist and m3 muscarinic antagonist activities patent thumbnailNew cyclohexylamine derivatives having ß2 adrenergic agonist and m3 muscarinic antagonist activities
The present invention relates to novel compounds having β2 adrenergic agonist and m3 muscarinic antagonist dual activity, to pharmaceutical compositions containing them, to the process for their preparation and to their use in respiratory therapies.. .
Almirall, S.a.


 Mask for the respiratory therapy with dedicated access for a nasogastric tube patent thumbnailMask for the respiratory therapy with dedicated access for a nasogastric tube
A mask for the respiratory therapy with dedicated access for a nasogastric tube comprising a shaped shell (12) at least covering mouth, nose and eyes of a patient (11), and provided, along a perimeter (13) which is suitable for being placed in contact against the patient's face, with a sealing gasket (14), said shaped shell (12) being provided with at least one inlet fitting (15) for the mixture of air and oxygen, said mask also comprising a neckpiece (20) provided with a plurality of prongs (21), each joined in a fixed or removable manner to a corresponding fastening point (17), distributed over the perimeter (13) of the shaped shell (12), is provided with a pneumatic-sealed dedicated access (30) for a nasogastric tube (31), wherein the shaped shell (12) bears a hole (32) having sufficient dimensions for the passage of the end of the nasogastric tube.. .
Dimar S.r.i.


 Seal mask for the respiratory therapy patent thumbnailSeal mask for the respiratory therapy
An improved-seal mask for the respiratory therapy of the type comprising a shaped shell (12) at least covering mouth, nose and eyes of a patient (11), and provided, along a perimeter (13) which is suitable for being placed in contact against the patient's face, with a sealing gasket (14), said shaped shell (12) being provided with at least one inlet fitting (15) for the mixture of air and oxygen, said mask also comprising a neckpiece (20) provided with a plurality of prongs (21), each joined in a fixed or removable manner to a corresponding fastening point (17), distributed over the perimeter of the shaped shell (12), is provided with five fastening points (17) for the neckpiece (20), wherein two upper fastening points (17′) are arranged at the height of the eyes, symmetrically with respect to a sagittal plane, two lower fastening points (17″) are arranged at the height of the chin, symmetrically with respect to a sagittal plane, and a fifth fastening point (17′″) is arranged centrally along an upper edge (18) of the mask suitable for resting on the forehead, namely in the sagittal plane.. .
Dimar S.r.l.


 Improved  the administration of a pulmonary surfactant by atomization patent thumbnailImproved the administration of a pulmonary surfactant by atomization
The system allows optimizing the dispensing of aerosol medicaments. In particular the system allows the administration of an exogenous pulmonary surfactant to very young patients (e.g.
Chiesi Farmaceutici S.p.a.


 Nasal douche with valve that can be actuated by respiratory air patent thumbnailNasal douche with valve that can be actuated by respiratory air
A nasal douche having a valve, container part and cap part, wherein the container part serves to receive irrigation liquid and carries cap part. The cap part has a nose attachment with an outlet opening for irrigation liquid connected fluidically to interior of container part via discharge channel, wherein nose attachment is intended to be attached to a nostril of the user.

Formulations useful in the treatment of proliferative diseases affecting the respiratory tract


The present application provides a pharmaceutical formulation comprising a folate receptor (fr)-targeting antineoplastic substance or composition, wherein the pharmaceutical formulation is configured for administration by inhalation, wherein the fr-targeting antineoplastic substance or composition is comprised in a nanoparticle and wherein the nanoparticles are comprised in microparticles, and its use in the treatment of a proliferative disease affecting at least part of the respiratory tract. The present application further provides a pharmaceutical formulation comprising an antineoplastic agent and a fr-targeting excipient, for use in the treatment of a proliferative disease affecting at least part of the respiratory tract..
Universite Libre De Bruxelles


P13k inhibitor for treatment of respiratory disease


The present invention is directed to compounds and pharmaceutically acceptable salts thereof which are inhibitors of the activity or function of the phosphoinositide 3′oh kinase family (hereinafter pi3k) for use in the treatment or prevention of respiratory infections, the treatment of airway damage, and/or the prevention of airway injury in patients.. .
Glaxosmithkline Intellectual Property Development Limited


Aclidinium for use in improving the quality of sleep in respiratory patients


The present disclosure provides aclidinium or any of its stereoisomers or mixture of stereoisomers, or a pharmaceutically acceptable salt or solvate thereof, for improving the quality of sleep in respiratory patients.. .
Almirall, S.a.


Avian tincture


An avian tincture composition and associated methods for producing the same for treatment of the avian species with the avian tincture. The avian tincture may be used in the treatment of abscesses, inflamed and swollen leg joints, respiratory issues, wounds, infection, and acute disease or parasite overload conditions..

Systems and methods to increase survival with favorable neurological function after cardiac arrest


A system includes a guidance device that provides feedback to a user to compress a patient's chest at a rate of between about 90 and 110 compressions per minute and at a depth of between about 4.5 centimeters to about 6 centimeters. The system includes a pressure regulation system having a pressure-responsive valve that is configured to be coupled to a patient's airway.
Advanced Circulatory Systems, Inc.


Respiratory effect reduction in catheter position sensing


A method, including positioning body-electrodes in galvanic contact with a body of a patient and locating a probe in the body of the patient. The method further includes tracking positions of the probe during respiration of the patient and determining indications related to impedances between the body-electrodes during the respiration.
Biosense Webster (israel) Ltd.


Improved oxygenating apparatus


A disposable oxygenation apparatus used to apply an oxygen enriched, positive pressure to a patient's airway where a respiratory device is in situ or is to be used, to decrease the incidence of desaturation and with an lma in situ to assist in maintaining the patient's vocal cords open during recovery after anaesthesia. The apparatus includes a passageway or passageways extending therethrough, an expiratory valve or valves located in or adjacent an outlet for controlling the passage of expired air from said patient during expiration, a primary inspiratory valve located in or adjacent a primary inlet, for controlling oxygen or oxygen rich air flowing through the passageway or passageways from a collapsible reservoir bag, and a secondary inspiratory valve located in or adjacent a secondary inlet for controlling entry of ambient air in from an exterior of the apparatus during inspiration when the collapsible reservoir bad has been substantially emptied..
Wallis Coombe Pty Ltd As Trustee For Sleuky Family Trust


Control for pressure of a patient interface


A method of an apparatus control pressure in the patient interface. A vent valve may be used with a respiratory device, where the vent valve may selectively block fluid communication between components, such as the flow generator, the patient interface, and/or the vent.
Resmed Limited


Systems and methods for heating and humidifying inspired gases during mechanical ventilation


Systems and methods for heating and/or humidifying a respiratory gas or gas mixture delivered to a human or animal patient during spontaneous or mechanical ventilation.. .
Flexicare, Inc.


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Humidifier for respiratory apparatus


A flexible tape heater (110) in a patient conduit (112) may be used to heat the flow of gas in the patient conduit (112) that is delivered to the patient mask (116). The thin, flat and extended nature of the flexible tape heater (110) may enhance heat transfer with the gas flow whilst also providing low impedance to the gas flow.
Resmed Limited


Breathing assistance apparatus


Breathing assistance apparatus for treating sleep apnoea are described. More specifically, nasal interface for the supply of respiratory gases, but most particularly positive pressure gases are described.
Fisher & Paykel Healthcare Limited


Systems and methods for selectively blocking respiratory air flow


Systems, devices and methods for selectively blocking respiratory air flow to portions of a lung are disclosed. For example, one bronchus of a lung may be sealed off while another bronchus remains open to air flow.
Endoclear Llc


Methods and devices for the detection of hypopnoea


Automated methods provide hypopnea detection for determining a hypopnea event and/or a severity of a hypopnea event. In some embodiments, a calculated short-term variance of a measured respiratory flow signal are compared to first and second proportions of a calculated long-term variance of the measured flow signal.
Resmed Limited


Invention


The present invention concerns a neuroglobin agonist for use in the treatment or prevention of a mitochondrial disease associated with respiratory chain complex i (rcci) deficiency and/or respiratory chain complex iii (rcciii) deficiency.. .
Institut National De La Sante Et De La Recherche Medicale (inserm)


Prrsv gp5 based compositions and methods


The disclosure includes compositions and methods for the production of an immune response against porcine reproductive and respiratory syndrome (prrs) virus, or prrsv. The disclosure is based in part on the use of two or more peptide domains, each with a different sequence, from the prrsv gp5 protein ectodomain.
Mj Biologics, Inc.


Pi3k inhibitor for treatment of respiratory disease


The present invention is directed to compounds and pharmaceutically acceptable salts thereof which are inhibitors of the activity or function of the phosphoinositide 3′oh kinase family (hereinafter pi3k) for use in the treatment or prevention of respiratory infections, the treatment of airway damage, and/or the prevention of airway injury in patients with a pi3kδ mutation.. .
Glaxosmithkline Intellectual Property Development Limited


Novel compounds as respiratory stimulants for treatment of breathing control disorders or diseases


The present invention includes a composition comprising a compound, such as a 2,4,6-triamino-1,3,5-triazine, 2,4,6-triaminopyrimidine, 2,4-diamino-6,7-dihydro-5h-pyrrolo[2,3-d]pyrimidine or 2,4-diamino-7h-pyrrolo[2,3-d]pyrimidine, that is useful in the treatment of breathing control diseases or disorders in a subject in need thereof. The present invention also includes a method of treating a respiratory disease or disorder in a subject in need thereof, comprising administering to the subject a therapeutically effective amount of a pharmaceutical composition of the invention.
Galleon Pharmaceuticals, Inc.


Methods for treating or preventing acute vascular leak


The invention features methods, devices, pharmaceutical compositions, and kits for treating or preventing acute vascular leak. Such methods may involve contacting an effective amount of bosutinib for treating or preventing acute vascular leak with a subject in need thereof.
The Brigham And Women's Hospital, Inc.


Compositions and methods for treatment of respiratory tract infections


This invention teaches a novel treatment of patients infected with influenza virus in early stages of the disease, with liposomes called α-gal/sa liposomes, in order to decrease the infection period and decrease further complications by this disease. The treatment is based on inhalation of biodegradable liposomes that present two types of carbohydrate epitopes: α-gal epitopes with the structure galα1-3galβ1-4(3)glcnac-r) and sialic acid (sa) epitopes.

Alertness device, seat, and determining alertness


An alertness device includes: a respiration sensor that obtains respiratory data of a person; a calculation unit; a waveform generation unit that generates a respiratory interval (ri) waveform which is a transition in a predetermined time period of an ri which is an interval for one respiration; and a determination unit. The calculation unit calculates an average value of the ri and rrmssdn in a predetermined time period.
Public University Corporation Nagoya City University


Smart electronic vaporizer


The design and structure as well as the control scheme of a smart electronic vaporizer device having a micro-machined (a.k.a. Mems, micro electro mechanical systems) mass flow sensor and control electronics that provide the vaporizing process in proportional to the user inhalation flowrate or strength for the best simulation of the experience for traditional cigarette.
Wisenstech Inc.


Face mounted extreme environment thermal sensor


A system is provided for the display of thermal data in a respiratory mask, the system comprising: a first respiratory mask frame; a lens disposed in the respiratory mask frame disposed in front of eyes of the user; a transparent display, being detachably mounted to the respiratory mask and displaying thermal imaging data.. .
Bae Systems Information And Electronic Systems Integration Inc.


Azaindoles as respiratory syncytial virus antiviral agents


Compositions containing these compounds as active ingredient and processes for preparing these compounds and compositions.. .

Cooling device for a protective respiratory apparatus


A cooling device (10), for a protective respiratory apparatus (100), has a housing (20), a breathing bag (30) arranged in the housing (20) with an inlet (32) for respiratory air (a) and an outlet (34) for cooled respiratory air (a) and a spring plate (40) with a spring device (42) to apply a spring force to the breathing bag (30). Between the housing (20) and at least one section of an outer side (36) of the breathing bag (30) an cooling air channel (50) is formed.
DrÄger Safety Ag & Co. Kgaa


Headgear


Headgear for a respiratory interface comprising multiple separate sections of material joined to form the headgear and different levels of resilient extensibility or stretchability in at least four different parts or straps of the headgear.. .
Fisher & Paykel Healthcare Limited


Automated control for detection of flow limitation


A respiratory flow limitation detection device, which can include an airway pressure treatment generator, determines a flow limitation measure 506 based one or more shape indices for detecting partial obstruction and a measure of a patient's ventilation or respiratory duty cycle. The shape indices may be based on function(s) that ascertain the likelihood of the presence of m-shaped breathing patterns and/or chair-shaped breathing patterns.
Resmed Limited


Ultrasonic energy measurements in respiratory drug delivery devices


Systems and methods for delivering medicament to a subject use one or more sensors to generate signals that represent characteristics of the ultrasonic energy emitted by a respiratory medicament delivery device during operation. Parameters based on these signals indicate energy amplitude in one or more frequency ranges.
Koninklijke Philips N.v.


Thermostable respiratory synctial virus (rsv) vaccine compositions


Methods for improving the drying yield and stability of rsv vaccines comprising a highly thermolabile enveloped live virus and/or one or more rsv protein subunits, are described. Methods for rapid drying of rsv formulations containing between 17.5% and 60% w/w of a non-polymeric sugar and using either conduction or radiation dominant drying mechanisms, are disclosed.
Merck Sharp & Dohme Corp.


Non-replicating probiotic micro-organisms protect against upper respiratory tract infections


The present invention relates to non-replicating probiotic micro-organisms and their health benefits. For example, the present invention relates to compositions comprising non-replicating probiotic micro-organisms for use in the treatment of prevention of upper respiratory tract infections and/or their symptoms.
Nestec S.a.


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Calcium glycerophosphate for treating and preventing respiratory diseases or conditions


Calcium glycerophosphate is found to be effective in treating and preventing a disease, disorder and/or condition of the respiratory system. The disease, disorder and/or condition is related to an obstructive or a restrictive condition of the respiratory airway.
Prelief Inc.


Treatment of asthma and chronic obstructive pulmonary disease with anti-proliferate and anti-inflammatory drugs


Embodiments of the present invention provide a method for treatment of respiratory disorders such as asthma, chronic obstructive pulmonary disease, and chronic sinusitis, including cystic fibrosis, interstitial fibrosis, chronic bronchitis, emphysema, bronchopulmonary dysplasia and neoplasia. The method involves administration, preferably oral, nasal or pulmonary administration, of anti-inflammatory and anti-proliferative drugs (rapamycin or paclitaxel and their analogues)..
Lutonix, Inc.


Method and effective detection of respiratory blockage using co2 monitor


A system and method are provided to detect a possible respiratory blockage by using personalized carbon dioxide (co2) concentration change patterns. The personalized change patterns can intelligently learn new change pattern to increase its accuracy.

On-airway pulmonary function tester


A compact, on-airway, respiratory gas analyzer for performing pulmonary function tests incorporates an ir spectroscopy light guide having a curved, rather than linear, sample chamber that lies transverse to a direction of respiratory gas flow. Cooperating with the sample chamber is an impact plate that functions to steer respiratory and test gases impinging on the impact plate into the curved sample chamber.
Mgc Diagnostics Corporation


On-airway pulmonary function tester


A compact, on-airway, respiratory gas analyzer for performing pulmonary function tests incorporates an ir spectroscopy light guide having a curved, rather than linear, sample chamber that lies transverse to a direction of respiratory gas flow. Cooperating with the sample chamber is an impact plate that functions to steer respiratory and test gases impinging on the impact plate into the curved sample chamber.
Mgc Diagnostics Corporation


Method and system for monitoring physiological and athletic performance characteristics of a subject


The present invention is directed to systems and methods for monitoring characteristics of a subject. A system according to an exemplary embodiment of the invention includes a sensor subsystem including at least one respiratory sensor disposed proximate to the subject and configured to detect a respiratory characteristic of the subject, wherein the sensor subsystem is configured to generate and transmit at least one respiratory signal representing the respiratory characteristic, and at least one physiological sensor disposed proximate to the subject and configured to detect a physiological characteristic of the subject, wherein the sensor subsystem is configured to generate and transmit at least one physiological signal representing the physiological characteristic, and a processor subsystem in communication with the sensor subsystem, the processor subsystem being configured to receive at least one of the at least one respiratory signal and the at least one physiological signal..
Adidas Ag


Medical device for the detection, measurement, in an unbloody and non-invasive manner, and transmission of vital, biomedical parameters, such as cardiovascular and respiratory parameters, of a human body


A medical device for detecting, measuring and transmitting vital parameters and biomedical data such as the continuous or instantaneous recording of an electrocardiography, acquisition of a doppler ultrasonography of ascending aorta and of a echocardiography, with immediate or remote operations, by means of units inserted in the device, on the human body, in a non-invasive way, comprising: a flexible strip-shaped support adapted to be applied on the human body in the area of the neck; one or more units adapted to detect body parameters; one or more connection interfaces for transmitting and receiving data and the parameters towards external units; hardware and software electronic components integrated inside the flexible support and adapted to receive the body parameters from the one or more units, store them, organize them and transmit them by connection interfaces; a sim card allowing transmission and reception.. .

Systems and methods for detecting infectious diseases


Systems, methods, and devices for detecting infections in a clinical sample are provided. Small-volume clinical samples obtained at a point-of-service (pos) location and may be tested at the pos location for multiple markers for multiple diseases, including upper and lower respiratory diseases.
Theranos, Inc.


Virus causing respiratory tract illness in susceptible mammals


The invention relates to the field of virology. The invention provides an isolated essentially mammalian negative-sense single-stranded rna virus (mpv) within the subfamily pneumovirinae of the family paramyxoviridae and identifiable as phylogenetically corresponding to the genus metapneumovirus and components thereof..
Erasmus Universiteit Medical Center Rotterdam


Antiviral compounds


Disclosed herein are new antiviral compounds, together with pharmaceutical compositions that include one or more antiviral compounds, and methods of synthesizing the same. Also disclosed herein are methods of ameliorating and/or treating a paramyxovirus viral infection with one or more small molecule compounds.
Alios Biopharma, Inc.


Novel compounds and pharmaceutical compositions thereof for the treatment of inflammatory disorders


Wherein r1a, r1b, r2, r4, r5, r6a, r6b, r7, r8, w, x, cy, and the subscript a are as defined herein. The present invention relates to compounds inhibiting autotaxin (npp2 or enpp2), methods for their production, pharmaceutical compositions comprising the same, and methods of treatment using the same, for the prophylaxis and/or treatment of diseases involving fibrotic diseases, proliferative diseases, inflammatory diseases, autoimmune diseases, respiratory diseases, cardiovascular diseases, neurodegenerative diseases, dermatological disorders, and/or abnormal angiogenesis associated diseases by administering the compound of the invention..

Unpowered respiratory protective headset and body suit and additional improvements to personal protective equipment


The invention relates to unpowered respiratory protective headsets for personal protective equipment and personal protective bodysuits with an unpowered respiratory protective headset.. .
The Johns Hopkins University


Respiratory ventilation system with gas sparing valve having optional cpap mode and mask for use with same


A system for delivering gas to a patient. The system includes a gas control unit, a breathing circuit, a control switch, and a patient interface.
Capnia, Inc.


Attenuated mannheimia haemolytica strains


The present invention provides attenuated m. Haemolitica strains that elicit an immune response in animal against m.
The United States Of America, As Represented By The Secretary Of Agriculture


Methods and compositions for the reduction of neutrophil influx and the treatment of bronchopulmonary displasia, respiratory distress syndrome, chronic lung disease, pulmonary fibrosis, asthma and chronic obstructive pulmonary disease


The present invention relates generally to the use of recombinant human cc10 (rhcc10), also known as recombinant human uteroglobin, for use as a therapeutic in the treatment of respiratory distress syndrome (rds), bronchopulmonary dysplasia (bpd), chronic lung disease and/or pulmonary fibrosis, asthma and chronic obstructive pulmonary disease (copd). More particularly, the invention provides methods, including broadly the critical dosage ranges of rhcc10, which may be administered to safely and effectively treat the aforementioned conditions.
Therabron Therapeutics, Inc.


Novel anti-viral therapeutic


Anti-viral therapeutics for use in viral targets having vpg unlinkase activity, including the broad class of picornaviruses, and therapeutic methods directed at suppression of such activity are provided. Such anti-viral therapies for use against human rhinovirus, for example, are particularly desirable as they would lessen both the severity and duration of upper respiratory distress in both normal and asthmatic individuals.
The Regents Of The University Of California


Oral insert


The invention relates to an oral insert for positioning between the outer faces of the teeth and the lips of a user, comprising a strip having a length and a width and an inner and outer face, wherein in the region of the longitudinal centre the longitudinal sides have an indentation. The oral insert further comprises at least one respiratory opening penetrating through the strip and a first and second bite projection which protrude from the inner face of the strip.

Integrated ultrasound, oct, pa and/or florescence imaging endoscope for diagnosing cancers in gastrointestinal, respiratory, and urogenital tracts


A multimodality imaging system including ultrasound, optical coherence tomography (oct), photoacoustic (pa) imaging, florescence imaging and endoscopic catheter for imaging inside the gastrointestinal tract with real-time automatic image co-registration capability, including: an ultrasound subsystem for imaging; an optical coherence tomography (oct) subsystem for imaging, a pa microscopy or tomography subsystem for imaging and a florescence imaging subsystem for imaging. An invasive interventional imaging device is included with an instrumentality to take a tissue biopsy from a location visible on the ultrasound subsystem for imaging, on the optical coherence tomography (oct) subsystem for imaging, photoacoustic (pa) subsystem for imaging and florescence subsystem for imaging.
University Of Southern California


Apparatus and detecting health deterioration


There is provided an apparatus for detecting the deteriorating health of a patient receiving gas from a respiratory device. The apparatus comprises a sensor unit configured to monitor a flow rate or pressure of a gas that is flowing in a pipe that connects the respiratory device to a gas delivery device worn by the patient, and a processor configured to measure a respiratory rate of the patient based on variations in the flow rate or pressure of gas in the pipe and to implement a trend analysis of the measured respiratory rate.
Linde Aktiengesellschaft


Portable device for collecting particles and microorganisms


A portable device for collecting particles and microorganisms is provided. The device includes a cyclone enclosure for centrifuging air, external air inlet for admitting air into the enclosure, and air outlet connected by a coupling to an air inlet filter of an individual motorized respiratory protection appliance..
Bertin Technologies


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Securing device for a valve


A securing device for a valve of a pressurized gas tank of a respiratory protection device, characterized by a securing element, which can be moved from a closed position to a flow position, especially an open position, by applying a torque, wherein at least one part of a housing serves as an abutment for the securing element when the torque is applied, wherein the valve is closed in the closed position of the securing element and can be brought spontaneously into a flow position after applying a particular torque to the securing element.. .
Msa Europe Gmbh


Azabenzimidazoles as respiratory syncytial virus antiviral agents


Compositions contain these compounds as active ingredient and processes for preparing these compounds and compositions.. .

Indoles as respiratory syncytial virus antiviral agents


The prodrugs, n-oxides, addition salts, quaternary amines, metal complexes and stereochemically isomeric forms thereof; compositions containing these compounds as active ingredient and processes for preparing these compounds and compositions.. .

Histamine-3 receptor antagonists


The invention is directed to a compound of formula i, as defined herein, or a pharmaceutically acceptable salt thereof; a pharmaceutical composition containing a compound of formula i; and a method of treatment of a disorder or condition selected from the list consisting of acute myocardial infarction; memory processes disorders; dementia; cognition disorders such as alzheimer's disease; attention deficit disorder (add); attention-deficit hyperactivity disorder (adhd); cancers such as cutaneous carcinoma, medullary thyroid carcinoma and melanoma; meniere's disease; gastrointestinal disorders; inflammation; migraine; motion sickness; obesity; pain; septic shock; respiratory disorders (including allergic rhinitis, nasal congestion and allergic congestion) in a mammal, including a human, that may be effected by administering to said mammal a pharmacologically effective amount of a compound of formula i, or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable carrier.. .
Medisynergics, Llc


Respiratory mask assembly


A respiratory mask assembly for delivering breathable gas to a patient includes a frame to support one of at least first and second compliant patient interfaces and a forehead support adjustably mounted to the frame. The forehead support is structured and configured to be moved between a first position for use with the first patient interface and a second position relative to the frame for use with a second patient interface, whereby the forehead support maintains a horizontal offset distance with the first and second patient interfaces which is substantially constant..
Resmed Limited


Therapies, vaccines, and predictive methods for middle east respiratory syndrome virus (mers cov)


The present invention provides an isolated or synthesized protein fragment or peptide comprising at least one peptide sequence that is at least 50% homologous with at least one replikin peptide sequence identified in a mers cov. The at least one peptide sequence may be at least 80% homologous with at least one replikin peptide sequence identified in a mers cov.

Anti-inflammatory proteins and methods of use


A method and composition for reducing or alleviating inflammation in a subject is provided, including administering to the subject a therapeutically effective amount; of one or more isolated proteins respectively comprising an amino acid sequence set forth in seq id nos:1-31, or a biologically active fragment or variant thereof or combinations of these to thereby reduce or alleviate inflammation. Inflammation may be associated with a disease is a disease of the digestive tract such as chronic gastritis or an inflammatory bowel disease such as crohn's disease or ulcerative colitis, or a disease of the respiratory system, such as asthma, emphysema, chronic bronchitis, and chronic obstructive pulmonary disease..
James Cook University


Pyrazolo[1,5-a]pyrimidines as antiviral agents


The invention provides compounds and pharmaceutically acceptable salts and esters and compositions thereof, for treating viral infections. The compounds and compositions are useful for treating pneumovirinae virus infection including human respiratory syncytial virus infections..
Gilead Sciences, Inc.


Invasive intermittent negative pressure ventilation


The present invention introduces novel invasive intermittent negative pressure ventilation for treatment of adults ventilator dependent respiratory failure (vdrf) in various advanced neuromuscular disorders (nmds). It's a combination of invasive intermittent negative pressure ventilator (iinpv) and continues positive airway pressure (cpap) into transportable ventilator.

Compensation for heart movement using coronary sinus catheter images


Cardiac catheterization is carried out by introducing a catheter into the coronary sinus, acquiring a first set of 2-dimensional images of the catheter, thereafter acquiring a second set of 2-dimensional images of the catheter, and creating respective 2-dimensional models of the catheter in synchronized frames of the first set and the second set. The 2-dimensional models include respective tracked 2-dimensional paths of the catheter.
Biosense Webster (israel) Ltd.


Motion monitor


A system for monitoring the respiratory activity of a subject, which comprises one or more signal generating elements being kinematic or light emitting elements, applied to the thorax of a subject, for generating signals that are indicative of movement of the thorax of the subject; a receiver for receiving the generated signals during breathing motion of the subject; and one or more computing devices in data communication with the receiver, for analyzing the breathing motion. The more computing device is operable to calculate, in response to the received generated signals, the magnitude of a maximum displacement in 3d space of the one or more signal generating elements during a cycle of the breathing motion; and to calculate the magnitude of a current displacement in 3d space of the one or more signal generating elements during the breathing motion with respect to a reference tidal volume associated with the maximum displacement in 3d space..
Breathevision Ltd.


Personalized nutritional and wellness assistant


The invention pertains to the establishment, implementation and management of a personalized information system pertinent to a user's general health, wellness and/or sport performance. A novel set of portable devices with calorimetric, metabolic sensing, computing and communication capabilities are used for non-stop real-time measurement and display as well as long-term logging of highly accurate information about a user's metabolic state.
Lifeq Global Limited


Quantitative pupillometry as a bedside predictor of postoperative respiratory depression


A non-invasive bedside tool for monitoring central nervous system effects of opioids. The tool illustratively comprises a quantitative pupillometry system for predicting a probability of at least one opioid-related central effect based on detected pupillary effects..
Children's Hospital Medical Center




Respiratory topics:
  • Respiratory
  • Ventilation
  • Respiratory Distress Syndrome
  • Executable
  • Computer Readable
  • Expiration
  • Respiration
  • Sleep Apnea
  • Medical Device
  • Continuous Positive Airway Pressure
  • Ventilator
  • Acute Respiratory Distress Syndrome
  • Antagonist
  • Cardiovascular Health
  • Cardiovascular


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