|| List of recent Respiratory-related patents
| Automated interpretive medical care system and methodology|
Improved apparatus and methods for monitoring, diagnosing and treating at least one medical respiratory condition of a patient are provided, including a medical data input interface adapted to provide at least one medical parameter relating at least to the respiration of the patient, and a medical parameter interpretation functionality (104, 110) adapted to receive the at least one medical parameter relating at least to the respiration (102) of the patient and to provide at least one output indication (112) relating to a degree of severity of at least one medical condition indicated by the at least one medical parameter.. .
| Mupirocin antibiotic composition|
An antibiotic inhalation or irrigation composition for the treatment of bacterial infections especially in the respiratory tract, is provided. The antibiotic inhalation or irrigation composition may include a mixture of mupirocin as active pharmaceutical ingredient (api), and a micronized poloxamer composition as excipient.
| Trpm8 antagonists|
The invention relates to compounds acting as selective antagonists of transient receptor potential cation channel subfamily m member 8 (trpm8), and having formula (i). Said compounds are useful in the treatment of diseases associated with activity of trpm8 such as pain, inflammation, ischaemia, neurodegeneration, stroke, psychiatric disorders, itch, irritable bowel diseases, cold induced and/or exhacerbated respiratory disorders and urological disorders..
| Biphenylcarboxamides as rock kinase inhibitors|
The present invention relates to new kinase inhibitors, more specifically rock inhibitors, compositions, in particular pharmaceuticals, comprising such inhibitors, and to uses of such inhibitors in the treatment and prophylaxis of disease. In particular, the present invention relates to new rock inhibitors, compositions, in particular pharmaceuticals, comprising such inhibitors, and to uses of such inhibitors in the treatment and prophylaxis of disease.
| Novel compounds and compositions for treatment of breathing control disorders or diseases|
The present invention includes compounds, and compositions comprising the same, that are useful in the treatment of breathing control diseases or disorders in a subject in need thereof. The present invention also includes a method of treating a respiratory disease or disorder in a subject in need thereof, comprising administering to the subject a therapeutically effective amount of a compound of the invention.
| Antibiotic composition for inhalation and irrigation|
An antibiotic composition for the treatment of bacterial infections, especially in the respiratory tract is provided. The antibiotic composition may include a mixture of gentamicin as active pharmaceutical ingredient (api), and a micronized poloxamer composition as excipient.
| Methods of treating chronic disorders with complement inhibitors|
In some aspects, the invention provides methods of treating a subject in need of treatment for a chronic complement-mediated disorder. In some aspects, the invention provides methods of treating a subject in need of treatment for a th17-associated disorder.
| Stabilized antiviral fusion helices|
Internally cross-linked peptides useful for interfering with respiratory syncytial virus (rsv) infection is based on rsv-f protein. These peptides are capable of reducing infection in cellular and animal models..
| Filter box assembly and filter unit|
A filter unit for use in a filter box assembly, the filter unit comprising a particulate filter layer and a gas filter layer, the particulate filter layer being configured to bias towards the gas filter layer, exerting pressure thereon. There is also described filter box assemblies (including a duel filter assembly) comprising the filter unit, and a respiratory protective device comprising the filter unit.
| Power management in respiratory treatment apparatus|
A respiratory treatment apparatus provides respiratory treatment with improved power management control to permit more efficient power consumption and power supply units, such as battery powered operation. In one embodiment, power management prioritizes the flow generator (104) over other accessories such as the heating elements (111, 135) of a humidifier (112) and/or a delivery tube.
| Hybrid self-rescue equipment|
Described herein is a safety breathing apparatus (5) having a delivery element configured to deliver respirable gas to a respiratory system of a user. The apparatus includes a breathing hose (25) in fluid communication with a first source of respirable gas (15).
|Device for the medical care of a patient in an emergency|
A device (1) for the medical care of a patient in an emergency which comprises an item of clothing (2) which may be worn by the patient on the body and monitoring devices (8, 9) arranged on the item of clothing (2), which may monitor at least one physiological function of the patient, in order to detect an emergency. The device further comprises a cardiac compression device (3, 4) arranged on the item of clothing (2), which is operatively connected to the monitoring device (8, 9), in order to treat the patient with a cardiac resuscitation when the monitoring device (3, 4) determines an emergency, and a defibrillator (5, 6, 7) as well as the intraosseous delivery of drugs into the bone marrow cavity of the breast bone.
|Respiratory treatment system including physiological sensors|
An apparatus assesses a condition of a patient. The apparatus may contain a patient interface for communicating a treatment generated by a respiratory treatment apparatus to the respiratory system of a patient.
|Method and apparatus for detecting and treating heart failure|
Devices and systems provide methods of detecting a heart failure condition of a patient that may be based on one or more respiratory parameters of a patient. In an example embodiment, a monitoring device determines one or more heart failure condition indicators based on a measure of the patient respiratory airflow and/or a measure of treatment pressure.
|Pharmaceutical composition comprising a trpa1 antagonist and an anticholinergic agent|
The present invention relates to a pharmaceutical composition comprising a transient receptor potential ankyrin-1 receptor (“trpa1”) antagonist and an anticholinergic agent. Particularly, the present invention provides a pharmaceutical composition comprising a trpa1 antagonist having ic50 for inhibiting human trpa1 receptor activity of less than 1 micromolar and an anticholinergic agent; a process for preparing such composition; and its use in treating a respiratory disorder in a subject..
Compounds of formula (i) described herein are p38 mapk inhibitors and are useful as anti-inflammatory agents in the treatment of, inter alia, diseases of the respiratory tract. .
Compounds of formula (i) described herein are p38 mapk inhibitors and are useful as anti-inflammatory agents in the treatment of, inter alia, diseases of the respiratory tract.. .
|Novel lactic acid bacterium having iga production promoting activity, and use thereof|
Disclosed are: a lactic acid bacterium belonging to lactobacillus kunkeei, the bacterium having a higher iga production inducing activity than that of lactobacillus strain gg (atcc53103), and a lower mitogenic activity and a lower il-2 production inducing activity than those of listeria strain egd; and a food composition, a pharmaceutical composition, a cosmetic composition, an immunostimulant for preventing the infection by pathogens or viruses that invade through the respiratory or esophageal mucosa, and an intestinal immunostimulant for preventing or alleviating food poisoning, each of which contains the lactic acid bacterium or treated cells of the lactic acid bacterium.. .
|Methods of using krill oil to treat risk factors for cardiovascular, metabolic, and inflammatory disorders|
This invention discloses methods of using krill oil and compositions comprising krill oil to treat risk factors for metabolic, cardiovascular, and inflammatory disorders. The present invention also relates to methods of using compositions comprising krill oil to modulate biological processes selected from the group consisting of glucose metabolism, lipid biosynthesis, fatty acid metabolism, cholesterol biosynthesis, and the mitochondria respiratory chain.
|Combined antigen and dna vaccine for preventing and treating rsv infection|
The present disclosure relates to treating and preventing symptoms of respiratory syncytial virus (rsv) infection using a combination vaccine containing an rsv antigen and a dna encoding the rsv antigen.. .
|Anti-human respiratory syncytial virus (rsv) antibodies and methods of use|
Provided herein are antibodies or antigen-binding fragments thereof that immunospecifically bind to the fusion (f) protein of respiratory syncytial virus (rsv). Also provided are methods for of prevention, treatment and diagnosis of viral infection and/or the treatment of one more symptoms of rsv-mediated disease.
|Aerosol formulation for copd|
The stable aerosol solution formulations comprising glycopyrronium chloride are useful for administration to patients with copd and other respiratory conditions.. .
|Close proximity airborne influenza/pathogen mitigator|
Close proximity, including conversations at closer than three (3) feet apart, facilitates disease transfer via airborne pathogens. This transfer can be mitigated by the present invention, which is directed towards methods, systems and apparatuses to produce a predictably shaped and minimally intrusive air barrier that may comprise an airborne disinfectant, to divert and or render harmless and to divert and negate close proximity airborne pathogens, such as influenza and severe acute respiratory syndrome, etc., and other airborne particulates transferred from an infected person towards the face of an unfortunate recipient at normal conversational distances apart from each other, and/or to divert and render harmless such airborne particulates..
|Respiratory gas flow sensor with sampling port|
The accurate measurement of inspired and expired gas volume flow and gas composition are important in respiratory therapy. Combining the two measurement functions often results in excessive deadspace and/or in the two measurement systems adversely affecting each other.
|Bioimpedance spectrography system and method|
A device and method for bioimpedance spectrography is corrected for breathing artefacts. A breathing signal is used in conjunction with the impedance signal to adjust for the time within the respiratory cycle at which the measurements are made.
|Sleep monitoring system|
A sleep monitoring system includes an ecg device (2) and a respiration inductance plethysmogram (3) which monitor cardiac activity and physical (ribcage) respiration respectively and feed representative signals to a digital data processor. Operations (5-9) process the beat interval data, while in a second thread, operations (20-24) independently process the amplitude modulation of the ecg data caused by the respiratory motion of the subject.
|Programmable segmented volumetric modulated arc therapy for respiratory coordination|
The invention designs a segmented short-arc vmat plan, modified from the original vmat plan, to fit the breath-hold interval. The modified vmat of the invention has the advantages of its applicability to different planning systems for variously long arcs and its preprogrammed arc segmentation for summated dose consistency.
|Novel urea and thiourea derivatives|
The present application discloses compounds of formula (i) wherein x is ═o, ═s, ═nh, ═noh and ═no-me; a is —c(═o)—, —s(═o)2—, —c(═s)— and p(═o)(r5)—; b is, —o—, —(ch2)3-6—, and o—(ch2)2-5—; d is, —o—, —cr7r8— and —nr9; m is 0-12, n is 0-12, m+n is 1-20; p is 0-4; r1 is opt.sub. Heteroaryl; and pharmaceutically acceptable salts thereof, and prodrugs thereof.
|Use of glutaryl histamine for the treatment of respiratory tract diseases|
The invention relates to a medicament for the treatment of respiratory tract diseases selected from the group including rhinosinusitis, sinusitis, tonsillitis, bronchiolitis, pneumonia, and acute respiratory distress syndrome, wherein the medicament comprises glutaryl histamine or a pharmaceutically acceptable salt thereof in an effective amount. The invention also relates to use of glutaryl histamine or a pharmaceutically acceptable salt thereof for manufacture a medicament for the treatment of a respiratory tract disease.
|Methods for preventing or treating certain disorders by inhibiting binding of il-4 and/or il-13 to their respective receptors|
The present disclosure relates to methods of treating, ameliorating or preventing a disorder comprising administering a therapeutically effective amount of a composition comprising a protein which inhibits il-4 and/or il-13 from binding to their respective receptors to a subject in need thereof. In some embodiments, the disorder is preferably associated with an increase of the th2 immune response.
|Probiotics for use in reducing the incidence and duration of illness|
The present invention provides probiotic compositions suitable for reducing the incidence and duration of human illness. In particular, the present invention provides methods and compositions suitable for preventing disease in young children.
|System and method for magnetic resonance imaging based respiratory motion correction for pet/mri|
A method and system for magnetic resonance imaging (mri) based motion correction in position emission tomography (pet) images is disclosed. A static 3d magnetic resonance (mr) image of a patient is received.
|Electrical heater with particular application to humidification and fluid warming|
A humidifier includes a tub configured to contain a supply of water and a heater including a first polymer film having an electrically conductive circuit provided upon a surface. The first polymer film is electrically insulating and the tub is formed of molded resin and the heater is molded at least partially within the resin.
|Adjustable and biased-open unidirectional speaking valve|
A speaking valve for management of a patient's airway comprising a body rotatably and removably attachable to a tracheotomy tube, the body having a first end communicable with the tracheotomy tube and a second end distal from the first end, an offset opening formed in the second end, a ramp disposed within the body, a ball having a diameter disposed within the chamber, the ball being adapted to be guided up and down the ramp and able to partially close the opening in the second end of the body, and the body and hence the chamber therein, at the option and control of the patient, wherein the ball is adapted to move up and down the ramp opening and partially closing the opening in the second end of the body and, as selected, exhalation by the patient proceeds through the patient's upper respiratory system and facilitates speaking by the patient.. .
|Peripheral nerve field stimulation control|
Peripheral nerve field stimulation (pnfs) may be controlled based on detected physiological effects of the pnfs, which may be an efferent response to the pnfs. In some examples, a closed-loop therapy system may include a sensing module that senses a physiological parameter of the patient, which may be indicative of the patient's response to the pnfs.
|Apparatus for testing respiratory function|
A respiratory function testing apparatus capable of testing a respiratory function of a subject more accurately. In the apparatus, a respiratory state detection unit acquires a first signal representative of different inspiratory volumes corresponding to a plurality of breaths of the subject and a second signal representative of intrapleural pressures corresponding to the respective different inspiratory volumes, and detects a plurality of respiratory states corresponding to the different inspiratory volumes and their corresponding intrapleural pressures.
|System and method for monitoring cardiorespiratory parameters|
An apparatus, system, and method is disclosed for monitoring the motion, breathing, heart rate of humans in a convenient and low-cost fashion, and for deriving and displaying useful measurements of cardiorespiratory performance from the measured signals. The motion, breathing, and heart rate signals are obtained through a processing applied to a raw signal obtained in a non-contact fashion, typically using a radio-frequency sensor.
|Rtp801l sirna compounds and methods of use thereof|
The invention provides chemically modified sirna oligonucleotides that target rtp801l, compositions comprising same and to the use of such molecules to treat, inter alia, respiratory diseases including acute and chronic pulmonary disorders, eye diseases including glaucoma and ion, microvascular disorders, angiogenesis- and apoptosis-related conditions, and hearing impairments.. .
|Novel soft rock inhibitors|
In addition, the invention relates to methods of treatment and use of said compounds in the manufacture of a medicament for the application to a number of therapeutic indications including sexual dysfunction, inflammatory diseases, ophthalmic diseases and respiratory diseases.. .
|Combinations of medicaments, containing pde4-inhibitors and ep4-receptor- antagonists|
At least one ep4 receptor antagonist (2), the preparation thereof and the use thereof for the treatment of respiratory complaints.. .