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|| List of recent Respiratory-related patents
| Mcp-1 binding nucleic acids and use thereof|
The present invention is related to a nucleic acid molecule capable of binding to mcp-i, whereby the nucleic acid molecule is for use as a medicament for the treatment and/or prevention of a chronic disease or chronic disorder, preferably selected from the group consisting of chronic respiratory disease, chronic kidney disease and systemic lupus erythematosus.. .
Noxxon Pharma Ag
| Treatment of respiratory depression|
Tricyclic dibenzothiazepine compounds for use in the treatment of respiratory depression.. .
| Pharmaceutical product comprising a p38 kinase inhibitor and a second active ingredient|
The invention provides a pharmaceutical product, kit or composition comprising a first active ingredient which is n-cyclopropyl-3-fluoro-4-methyl-5-[3-[[1-[2-[2-(methylamino)ethoxy]phenyl]cyclopropyl]amino]-2-oxo-1(2h)-pyrazinyl]-benzamide or a salt thereof, and a second active ingredient selected from: a non-steroidal glucocorticoid receptor (gr receptor) agonist; an antioxidant; a β2 adrenoceptor agonist; a ccr1 antagonist; a chemokine antagonist (not ccr1); a corticosteroid; a crth2 antagonist; a dpi antagonist; an histone deacetylase activator; an ikk2 kinase inhibitor; a cox inhibitor; a lipoxygenase inhibitor; a leukotriene receptor antagonist; a maba compound; an mpo inhibitor; a muscarinic antagonist; a pde4 inhibitor; a pparγ agonist; a protease inhibitor; a statin; a thromboxane antagonist; a vasodilator; or, an enac blocker (epithelial sodium-channel blocker); and its use in the treatment of respiratory disease.. .
| Compositions comprising a biological control agent and a fungicide from the group consisting of inhibitors of the respiratory chain at complex i or ii|
The present invention relates to a composition comprising at least one biological control agent. Furthermore, the present invention relates to the use of this composition as well as a method for reducing overall damage of plants and plant parts..
Bayer Cropscience Ag
| Oriental medicine compositions marked as sec 22 and sec 33 for improving children's underweight, low growth and depressed respiratory organ|
The present invention relates to oriental medicine compositions marked as sec 22 and sec 33 for improving digestive functions and respiratory functions for improving children's underweight, low growth and depressed respiratory organ, an oriental medicine derived therefrom, and methods of preparing them. According to an example of the present invention, the oriental medicine composition containing broiled fruit of crataegus pinnatifida, broiled root of atractylodes japonica, dried peel of citrus unshiu, broiled sprout of hordeum vulgare, broiled fruit of amomum xanthioides, root of zingiber officinale, dried fruit of zizyphi, and horn of cervus elaphus..
| Polyinosinic-polycytidylic acid (poly (i:c)) formulations for the treatment of upper respiratory tract infections|
The present invention concerns a composition comprising micro particles of polyinosinic-polycytidylic acid (poly (i:c)) and a carrier polymer selected from starch, alginate, blanose or dppc (dipalmitoylphosphatidylcholine) for use in preventing and/or treating viral infections of the upper respiratory tract or the common cold and a device, preferably a nasal delivery system, comprising said composition for use by a patient in need to prevent and/or treat infections or the common cold.. .
Janssen R&d Ireland
| Methods and uses for proprotein convertase subtilisin kexin 9 (pcsk9) inhibitors|
There is provided a method of treating an inflammatory response to infection and complications associated therewith, by administering a proprotein convertase subtilisin kexin 9 (pcsk9) inhibitor to a subject, in need thereof. There is also provided a method of treating or preventing treating or preventing renal failure; renal dysfunction; respiratory failure; respiratory dysfunction; or acute lung injury.
Cyon Therapeutics Inc.
| Body fluid expanders comprising n-substituted aminosulfonic acid buffers|
A buffered body fluid expander solution, in which the buffer is a physiologically acceptable buffer that is not an inorganic phosphate buffer, comprises calcium ions and magnesium ions at a concentration ratio of 5:1 to 1:1. The solutions are useful for the manufacture of medicaments and blood volume expanders, for treating hypovolemia or for treating the loss of extracellular and interstitial fluid in subjects suffering with burns, for treating respiratory and/or metabolic acidosis in a subject, for perfusion of the abdominal cavity during peritoneal dialysis of a subject with acute renal failure or an acute toxicity condition, for preventing and/or ameliorating reperfusion injury, and for delivering a therapeutic, test and/or synergistic agent to a subject, including a biological agent, such as at least one stem cell, peptide or genomic derived protein..
| Method and reducing radiation from ct measurement of respiratory cycles and ct scanner|
A method for reducing radiation from ct measurement of respiratory cycles and a corresponding ct scanner. The method includes: determining a lying direction of a patient to be measured; and setting a tube position for a first respiratory cycle measurement of the patient according to the lying direction..
General Electric Company
| Patient in-the-loop participatory care and monitoring|
Methods and systems for patient participatory care and monitoring are provided for applications including respiratory care, ecg monitoring, capnography, infusion pump alarm prevention/management, pressure sore prevention, incentive spirometry, consciousness monitoring during sedation, pain management and other care and monitoring modalities. A patient in-the-loop system includes an input interface for receiving data acquired from a monitoring, controlling or sensing device, a storage device for storing the data at a first location, and a processor for analyzing artifacts in the data and determining whether the patient provided a deliberate action with respect to the device as a response to a prompt or query.
University Of Florida Research Foundation, Incorporated
Control of pressure for breathing comfort
A respiratory treatment apparatus generates an indication of inspiration or expiration based on a measure of motor current of a flow generator. In an example, first and second current signals are derived from the measurement.
Resmed Motor Technologies Inc.
System and controlling flow during exhalation in a respiratory support system
The present disclosure pertains to an exhalation valve system (10) configured to control gas flow during exhalation of a subject (12). In some embodiments, the system comprises one or more of a pressure generator (14), a subject interface (16), one or more sensors (18), one or more processors (20), electronic storage (22), user interface (23), and/or other components.
Koninklijke Philips N.v.
Cough assistance and measurement system and method
Systems and methods are configured to inexsufflate a subject and provide cough-by-cough feedback during treatment and/or therapy of the subject. Through sensors that are included in the systems, various gas and/or respiratory parameters maybe measured and/or determined in real-time, such as, for example, peak cough flow and/or inspiratory tidal volume..
Koninklijke Philips N.v.
Method and adjusting respiratory mask sealing force
A mask assembly includes a mask with an inflatable bladder. The internal pressure of the inflatable bladder can be set to be higher than the delivered therapeutic pressure.
Rotating electrical connector adn respiratory gas delivery system employing same
A connection assembly for rotateably and electrically coupling an accessory to a main device includes a housing portion, a rotatable port assembly, and a wire assembly. An end of the port assembly is coupled to the accessory.
Synchronization of patient motion detection equipment with medical imaging systems
An improved system and method to acquire physiological information about a state of a subject, such as spect and pet information. The system generates a predetermine sequence of pulse signals and combines that sequence with a first physiological signal to generate a time-base signal.
Complete upper respiratory tract cleansing system and its use
An extracting device for diagnosis and treatment of diseases includes a tip equipped with a one-way liquid valve; a chamber equipped with a one-way air valve; and an elastic bulb for generating suctioning-pushing pressure when it is squeezed and released. When the user squeezes and releases the elastic bulb, the liquid will be drawn into the chamber through the tip.
Respiration assist apparatus and respiratory function test system
In an apparatus for assisting respirations of a subject in accordance with a predetermined reference respiration pattern defined as a sequence of reference respirations each having a reference respiratory volume for the subject, a respiration obtaining unit obtains, at a sampling time, an actual respiratory volume of the subject based on an actual respiration of the subject in accordance with the predetermined reference respiration pattern. A storing unit stores variation of the reference respiratory volumes for the subject.
Systems and methods for using physiological information
Systems and methods using a database of physiological information for the design, development, testing and use of therapeutics. In one aspect, the physiological information can include at least one of: hemodynamic monitoring information, pulmonary arterial pressure, cardiac output, heart rate, respiratory rate, peripheral vascular resistance, total peripheral resistance or dicrotic notch information.
Tritoqualine for use in the treatment of cystic fibrosis
The present invention relates to the use of a histamine h4 agonist molecule, the enantiomers of the (amino-7 triethoxy-4,5,6 oxo-1 dihydro-1,3 isobenzofurannyl-3)-1methoxy-8 methyl-2 methylenedioxy-6,7 tetrahydro-,2,3,4 isoquinoline or tritoqualine for the treatment of respiratory impairment caused by cystic fibrosis and the reduction and prevention of bronchial superinfections.. .
Compositions and methods for the treatment of cough
The invention relates to the compounds of formula i or its pharmaceutical acceptable salts, as well as polymorphs, solvates, enantiomers, stereoisomers and hydrates thereof. The pharmaceutical compositions comprising an effective amount of compounds of formula i, and methods for treating or preventing cough may be formulated for oral, buccal, rectal, topical, transdermal, transmucosal, intravenous, parenteral administration, syrup, or injection.
Methods for detecting and treating rhinovirus infection
The invention provides a method for evaluating the activity of an agent for treating rhinovirus infection or a symptom thereof, a method of detecting or monitoring rhinovirus infection, and a method of treating rhinovirus infection or a symptom thereof. Various embodiments comprise measuring expression of (i) one or more genes selected from the group consisting of cry2, b3gat3, c10orf95, and batf3, and (ii) one or more genes selected from the group consisting of rnft2, btg4, psd3, capn9, sult1e1, hey1, lrrc36, rab3b, aldh3b1, fam134b, fas, plscr1, clec2b, has2, mx1, sp110, gbp1, ifit3, ifit1, cxcl9, cxcl10, and cxcl11, from at least one biological sample to produce a gene expression profile, and comparing the gene expression profile to a reference gene expression profile.
Compositions and methods for the treatment of respiratory disorders
The invention relates to the compounds of formula i or its pharmaceutical acceptable salts, as well as polymorphs, solvates, enantiomers, stereoisomers and hydrates thereof. The pharmaceutical compositions comprising an effective amount of compounds of formula i, and methods for the treatment of respiratory disorders may be formulated for oral, buccal, rectal, topical, transdermal, transmucosal, intravenous, parenteral administration, syrup, or injection.
Pyrrolo[1,2-f][1,2,4]triazines useful for treating respiratory syncitial virus infections
Provided herein are formulations, methods and substituted tetrahydrofuranyl-pyrrolo[1,2-f][1,2,4]triazine-4-amine compounds of formula (i) for treating pneumovirinae virus infections, including respiratory syncytial virus infections, as well as methods and intermediates for synthesis of tetrahydrofuranyl-pyrrolo[1,2-f][1,2,4]triazine-4-amine compounds.. .
Macrocyclic and peptidomimetic compounds as broad-spectrum antivirals against 3c or 3c-like proteases of picornaviruses, caliciviruses and coronaviruses
Antiviral protease inhibitors, including macrocylic transition state inhibitors and peptidomimetics are disclosed, along with related antiviral compounds, and methods of using the same to treat or prevent viral infection and disease. The compounds possess broad-spectrum activity against viruses that belong to the picornavirus-like supercluster, which include important human and animal pathogens including noroviruses, sapoviruses, enteroviruses, poliovirus, foot-and-mouth disease virus, hepatitis a virus, human rhinovirus (cause of common cold), human coronavirus (another cause of common cold), transmissible gastroenteritis virus, murine hepatitis virus, feline infectious peritonitis virus, and severe acute respiratory syndrome coronavirus..
Methods, compounds and compositions for treatment of influenza and parainfluenza patients
A method of reducing or treating parainfluenza or influenza virus infection in an immunocompromised patient by administering to the respiratory tract of the patient a composition comprising a therapeutically effective amount of protein having sialidase activity.. .
X-ray positioning apparatus, x-ray positioning method, and attentional image photographing method
An x-ray positioning apparatus according to the present invention is provided with an x-ray video device that generates second x-ray image data in which a respiratory signal of a patient and first x-ray image data are related to each other, a positioning computer that generates patient platform control data for controlling a patient platform, and a photographing trigger generation apparatus that outputs a photographing trigger signal to an x-ray tube; the x-ray positioning apparatus is characterized in that the photographing trigger generation apparatus generates the photographing trigger signal, in accordance with a first frame rate and a second frame rate that is higher than the first frame rate, and in that the positioning computer generates the patient platform control data, based on a reference image and one x-ray image selected from consecutively photographed images that are photographed at the second frame rate.. .
Respiratory mask sealing interface
A sealing interface forms part of an apparatus for supplying a flow of respiratory gases to a user. The sealing interface comprises a foam or gel inner cushion and a thin resilient rubber outer sheath.
Respiratory mask having gas washout vent and making the mask
A washout vent for a mask for use with a system for supplying breathable gas pressurized above atmospheric pressure to an airway of a mammal for treatment of sleep disordered breathing, includes a solid mask section and a vent orifice extending through a thickness of the solid mask section and adapted for gas washout. The vent orifice includes opposed side walls providing a flow passage that allows gas to flow along the opposed side walls from an interior of the mask to atmosphere in use, and the opposed side walls defining at least a portion of a conic section having a length substantially greater than its width.
Control of flow and/or pressure provided by breathing apparatus
The invention comprises a method of operating a breathing apparatus comprising measuring a baseline breath flow parameter being respiratory rate and/or tidal volume or a parameter derived therefrom, varying the flow rate provided by the breathing apparatus, measuring a current breath flow parameter being respiratory rate and/or tidal volume or a parameter derived therefrom, comparing the baseline and current breath flow parameters, and altering operation of the breathing apparatus based on the comparison. The invention also comprises a breathing apparatus that implements the above method..
Method and oral flow therapy
A therapy system configured to wash out or flush out the oral and/or nasal cavity to reduce the effective dead space and reduce the work of breathing. The system may displace the expired air in the oral and/or nasal cavity with atmospheric air, or air with altered concentrations, for example, increased humidity, or oxygen levels.
Unitary respirator with molded thermoset elastomeric elements
A respiratory protection composite facepiece is disclosed and includes a polymeric rigid facepiece body portion having a first surface and a second surface and a silicone sealing facepiece element chemically bonded at least one of the first surface or the second surface. The first and second surfaces can be opposing major surfaces.
Method, apparatus, and system for measuring respiratory effort
A method, apparatus, and system for measuring respiratory effort of a subject are provided. A thorax effort signal and an abdomen effort signal are obtained.
Compositions and methods for the treatment of asthma and allergy
The invention relates to the compounds of formula i or its pharmaceutical acceptable salts, as well as polymorphs, solvates, enantiomers, stereoisomers and hydrates thereof. The pharmaceutical compositions comprising an effective amount of compounds of formula i, and methods for the treatment of asthma and allergy may be formulated for oral, buccal, rectal, topical, transdermal, transmucosal, intravenous, parenteral administration, syrup, or injection.
Wherein all the symbols have the same meanings as described in the specification, has two cyclic groups, particularly phenoxy groups at specific substitution positions and thus has high human s1p2 antagonistic activity. The compound may therefore be used as a therapeutic agent for s1p2-mediated diseases such as diseases resulting from vascular constriction, fibrosis and respiratory diseases..
Preparations of hydrophobic therapeutic agents, methods of manufacture and use thereof
The present invention further provides method of preparing nanocrystals of a hydrophobic therapeutic agent such as fluticasone or triamcinolone, pharmaceutical compositions (e.g., topical or intranasal compositions) thereof and methods for treating and/or preventing the signs and/or symptoms of disorders such as blepharitis, meibomian gland dysfunction or skin inflammation or a respiratory disease (e.g., asthma).. .
Aciex Therapeutics, Inc.
Transporter protein-coupled nanodevices for targeted drug delivery
A tripartite nanodevice comprising a targeting portion, a carrier portion, and at least one molecule to be delivered is provided. In particular, a gold nanoparticle linked to a targeting protein and capable of delivering a stimulant for the treatment of respiratory or disease is described.
Wayne State University
No/nitrogen gaseous mixture with a high no content for the treatment of severe hypoxemic respiratory failure
The invention concerns a gaseous medicine comprising a mixture of nitrogen monoxide (no) and nitrogen (n2) for use by inhalation for the treatment of hypoxemic respiratory failure linked to pulmonary vasoconstriction in humans, said gaseous mixture containing between 1200 and 4500 ppm by volume (ppmv) of nitrogen monoxide (no) and said hypoxemic respiratory failure being chosen from acute respiratory distress syndrome (ards) or persistent pulmonary hypertension of the newborn infant (pphn).. .
Air Liquidee Sante (international)
Antibodies against and methods for producing vaccines for respiratory syncytial virus
The present invention relates to novel respiratory syncytial virus (rsv) f peptides and compositions comprising them. The present invention also relates to methods of evaluating anti-rsv antibody binding to f peptides.
Packaging system for patient interface system
A packaging tray for a patient interface system, the patient interface system adapted to provide respiratory therapy, the packaging tray comprising: at least one cushion assembly region, each shaped to conform to at least a portion of a cushion assembly; a tube region shaped to conform to at least a portion of a tube; and a positioning and stabilising structure region shaped to conform to at least a portion of a positioning and structure.. .
Respiratory therapy apparatus
An inspiratory exerciser apparatus has a loop shape housing with a mouthpiece 1, an air inlet 2, an outlet 3 and a spring-loaded valve 4 that provides a restriction to inhalation through the inlet. The apparatus includes an electronics unit 60 that records use of the apparatus for download to a remote computer, such as via a connector port 65 or by wireless means.
Smiths Medical International Limited
Respiratory tubing set
The present invention relates to a respiratory tubing set for controlling breathing of a patient. A tubing set for controlling breathing of a patient includes a respiratory conduit.
The Periodic Breathing Foundation
Apparatus for treating a respiratory disorder with a power source connection
A respiratory device, such as a ventilator, for use in treating respiratory disorders and for preventing respiratory disorders. The respiratory device is configured to be powered from a range of different power sources including an internal battery, an external battery, ac power source or a dc power source.
Resmed Paris Sas
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Respiratory topics: Respiratory, Ventilation, Respiratory Distress Syndrome, Executable, Computer Readable, Expiration, Respiration, Sleep Apnea, Medical Device, Continuous Positive Airway Pressure, Ventilator, Acute Respiratory Distress Syndrome, Antagonist, Cardiovascular Health, Cardiovascular
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