|| List of recent Respiratory-related patents
|System and method for determining respiratory parameters from blood flow signals|
A system for determining one or more respiratory parameters of an individual may include a blood flow detection device configured to detect a blood flow signal of the individual, a blood flow determination module configured to form a blood flow waveform based on the blood flow signal, and a respiratory parameter analysis module configured to analyze the blood flow waveform and determine the respiratory parameter(s) from an analysis of the blood flow waveform.. .
|System and method for scaling a fluid responsiveness metric|
The present invention relates to physiological signal processing, and in particular to methods and systems for processing physiological signals to predict a fluid responsiveness of a patient. A medical monitor for monitoring a patient may include an input receiving a photoplethysmograph (ppg) signal representing light absorption by a patient's tissue, and a fluid responsiveness predictor (frp) calculator programmed to calculate an frp metric.
|Proteomics based diagnostic detection method for chronic sinusitis|
The invention provides for a proteomic approach for identification of specific bacterial protein profiles that may be used in the development of methods for the diagnosis of bacterial chronic sinusitis. The invention provides for methods for determining the presence of pathogenic bacteria in the upper respiratory tract of a subject using protein profiles of the pathogenic bacteria.
|Infectious cdna clone of european prrs virus and uses thereof|
The present invention belongs to the field of animal health and relates to a nucleic acid sequence which comprises the genome of an infectious genotype i (eu) prrs virus clone useful for studying porcine reproductive and respiratory syndrome (prrs), a viral disease affecting swine, and in the development of vaccines, therapeutics and diagnostics for the prophylaxis, treatment and diagnosis of prrs.. .
|Mask with integral cushion and forehead piece|
A respiratory mask has an adjustable forehead support member that is simple and inexpensive to manufacture. The forehead support member may be adjusted by rotating a forehead pad about an off-center bore or by bending an angular adjustment beam.
|Headgear for a respiratory mask and a method for donning a respiratory mask|
Headgear for a respiratory mask includes a strap arrangement comprising front strap portions adapted to be disposed over a patient's cheeks and each having a connector adapted for attachment to an airway interfacing portion, and a cover provided to each front strap portion and structured to at least partially encapsulate the front strap portion. The cover includes side portions adapted to be wrapped around the front strap portion and releasably fastened to one another..
|Electrically stimulated mask and/or associated components|
A respiratory assistance component is disclosed that changes shape when an electrical charge is provided. The amount of electrical charge that is applied may be based on values, characteristics, or user controlled parameters of the respiratory assistance system.
|Airway impedance measurement integrated with respiratory treatment devices|
Airway impedance of a subject using a respiratory treatment device can be measured, in accordance with one or more embodiments. A conduit is configured to communicate a flow of inhaled gas and a flow of exhaled gas to and from an airway of the subject using the respiratory treatment device.
|Biosignal measurement apparatus and biosignal measurement method|
A biosignal measurement apparatus includes: a potential difference measurement unit that measures a potential difference between a plurality of electrodes of an electrode unit placed on a user's chest; an ecg analysis unit that obtains an electrocardiogram (ecg) indicating a temporal variation of a cardiac potential of the user, from the potential difference measured by the potential difference measurement unit; an impedance measurement switching unit that determines a start timing of a first period which is a period not including an r wave, using the ecg obtained by the ecg analysis unit; an impedance measurement unit that measures an impedance between the plurality of electrodes in the first period; and a respiratory calculation unit that calculates respiratory information related to respiration of the user, based on a temporal variation of the impedance measured by the impedance measurement unit.. .
|Implantable cardiac device adapted to extract a patient's respiratory waveforms from an intrathoracic or intracardiac impedance, pressure and/or accelerometry input stream|
An implantable cardiac device is provided. The implantable cardiac device includes a sensing unit adapted to measure an intrathoracic or intracardiac impedance, pressure, and/or accelerometry input stream, which includes a patient's respiratory waveforms.
|Apparatus and method for detecting phrenic nerve stimulation|
An apparatus and method for detecting phrenic nerve stimulation (pns) including computing a power spectral density (psd) of spatial data of a sensor; determining two spectral magnitudes from the psd; computing a ratio of the two spectral magnitudes; and comparing the ratio to a threshold to detect pns. In one example, detecting pns includes computing a psd of spatial data of an externally placed sensor; determining a diaphragmatic spectral magnitude and a respiratory motion spectral magnitude from the psd; and computing a ratio of the diaphragmatic spectral magnitude to the respiratory motion spectral magnitude to detect pns.
|Compositions and methods of detecting respiratory pathogens using nucleic acid probes and subsets of beads|
The present disclosure is instructional for a multiplex nucleic acid amplification assay to detect and identify multiple respiratory pathogens.. .
The present invention relates to pharmaceutical compositions for inhalation comprising glycopyrrolate, a beta2-agonist, and optionally an inhaled corticosteroid; to a process for preparing such compositions and to the use of such compositions for the prevention and/or treatment of respiratory, inflammatory or obstructive airway disease.. .
|Pump unit and respiratory assistance device|
A pump unit includes a micro pump and an assist mechanism. The micro pump includes: a housing having an inflow port and an outflow port; and a pump device built in the housing, the pump device transporting a fluid from the inflow port to the outflow port.
|Method and system for patient-synchronized ventilatory assist with endotracheal through-flow|
A ventilatory assist system and method are disclosed. The system comprises a tube for connection to a patient's airway, inspiratory and expiratory tube lumens connected to the tube, an inspiratory air source connected to the inspiration tube lumen, and a controller of air pressure in the expiratory tube lumen.
|Exchanger assembly for respiratory treatment|
An exchanger conduit permits temperature and/or humidity conditioning of a gas for a patient respiratory interface. In an example embodiment, a conduit has a first channel and a second channel where the first channel is configured to conduct an inspiratory gas and the second channel configured to conduct an expiratory gas.
|Breathable retrieving device|
A retrieving device includes a body with at least one respiratory passageway formed in it through which a dog can breathe when holding the device in its mouth during retrieval. In some embodiments, the body includes two radially-large end sections that are harder for dogs to grasp with their mouths, two radially-midsize lateral sections positioned therebeween each defining lateral respiratory passageways for side-breathing by the dog, and a radially-narrow middle section positioned therebeween defining a forward/transverse respiratory passageway for front-breathing by the dog.
|System and method for identity confirmation using physiologic biometrics to determine a physiologic fingerprint|
The invention provides a method for verifying a person's identity, which includes obtaining a password and/or random key from a person, and comparing the obtained password and/or random key to a plurality of known passwords and/or random keys to determine a likely identity of the person. The method further includes measuring a specific biometric of the person, the specific biometric comprising a respiratory, cardiac, or other physiologic biometric, and comparing the measured specific biometric to the known specific biometric of the person that is associated with the obtained password and/or random key to verify the likely identity of the person..
|Acoustic respiratory monitoring sensor having multiple sensing elements|
According to certain described aspects, multiple acoustic sensing elements are employed in a variety of beneficial ways to provide improved physiological monitoring, among other advantages. In various embodiments, sensing elements can be advantageously employed in a single sensor package, in multiple sensor packages, and at a variety of other strategic locations in the monitoring environment.
|Apparatus and system for predictive health monitoring|
An apparatus and system are provided for monitoring an individual, a group or a community of individuals for respiratory infections. Predictive health data, such as waking peak expiratory flow rate (“wpf”) and basal metabolic temperature (“bmt”) are measured and charted to provide an indication of early stage respiratory infection.
|Novel compounds and pharmaceutical compositions thereof for the treatment of inflammatory disorders|
Wherein r1a, r1b, r2, r4, r5, r6a, r6b, r7, r8, w, x, cy, and the subscript a are as defined herein. The present invention relates to compounds inhibiting autotaxin (npp2 or enpp2), methods for their production, pharmaceutical compositions comprising the same, and methods of treatment using the same, for the prophylaxis and/or treatment of diseases involving fibrotic diseases, proliferative diseases, inflammatory diseases, autoimmune diseases, respiratory diseases, cardiovascular diseases, neurodegenerative diseases, dermatological disorders, and/or abnormal angiogenesis associated diseases by administering the compound of the invention..
|New cyclohexylamine derivatives having beta 2 adrenergic agonist and m3 muscarinic antagonist activities|
The present invention relates to novel compounds having β2 adrenergic agonist and m3 muscarinic antagonist dual activity, to pharmaceutical compositions containing them, to the process for their preparation and to their use in respiratory therapies.. .
|Novel peptidomimetics and their application|
Novel peptidomimetics exhibiting affinity for opioid receptors, possessing general formula show on fig. 1, for gastrointestinal or peripheral administration in the form of a pill, infusion, injection or implant in the treatment of peripheral opioids side effects, particularly constipation or/and respiratory depression..
|Identification of protective antigenic determinants of porcine reproductive and respiratory syndrome virus and uses thereof|
The invention relates to a polypeptide of a protective antigenic determinant (pad polypeptide) of porcine reproductive and respiratory syndrome virus (prrsv) and nucleic acids encoding a pad polypeptide. The pad polypeptide and nucleic acids encoding a pad polypeptide are useful in the development of antibodies directed to pad, vaccines effective in providing protection against prrsv infection, and diagnostic assays detecting the presence of pad antibodies generated by a pad-specific vaccine.
|Stethoscopy training system and simulated stethoscope|
Provided is a stethoscopy training system which is inexpensive and has a simple configuration, without using a device which measures a respiratory operation of a simulated patient. The stethoscopy training system for this objective is formed from: a simulated stethoscope (1) having a sound acquisition unit further comprising a location display means (1d), a tube, and ear pipes; a location sensing means (2) for sensing the location of the sound acquisition unit; biological sound database (3); a biological sound reproducing means (4); and a timing display means (5) for displaying a timing of a repetition of a reproduced respiratory sound.
|Hose management system for a respiratory therapy device|
A hose management system (30) for use with a system adapted to provide respiratory therapy. The system includes an elongated, flexible second hose (22).
|Collapsible patient conduit a respiratory therapy system|
An elongated flexible conduit (4) includes an flow element (24) having a first elongated wall segment (32) and a second elongated wall segment (44) that are connected together at their sides to form a wall (28) that is continuous in a circumferential direction perpendicular to the direction of elongation (8). The flow element is movable between a first configuration and a second configuration (68), with the first configuration being an expanded configuration, and with the second configuration being a collapsed configuration.
|Device for resuscitating victims of cardio-respiratory arrest|
The present invention comprises an insufflated air inlet (2a), an outlet (3a) for said insufflated air provided at the lower end of an air conveying tube (3) designed to penetrate the throat of the victim through the mouth, at least a first one-way valve (4) interposed between said air inlet (2a) and air outlet (3a) to allow the flow of air from said inlet (2a) to said outlet (3a) and prevent the flow of a fluid exhaled by the victim in the opposite direction, the body of said valve (4) including an outlet aperture (4a) for the exit of the fluid exhaled by the victim, and characterized in that the upper end of said insufflated air conveying tube (3) comprises a portion (3b) of tube (3) which is configured for internally receiving the body of said valve (4), the wall of said tube (3) including at least one outer hole (6) communicating with the aperture (4a) of the body of the valve (4) to allow discharging the fluid exhaled by the victim to the outside.. .
|Lighting device for respiratory humidifier and respiratory humidifier|
A lighting device for a respiratory humidifier (1) is provided, the humidifier comprising a liquid container (3) with a bottom plate and a housing (2) with a heating plate (8), wherein the heating plate (8) can be heated for heating the liquid in the liquid container (3), and wherein the bottom plate can be brought into contact with the heating plate (8), wherein the housing (2) comprises a light source (20) and a light exit portion (22), and the liquid container (3) comprises a light entrance portion (21), wherein the light proceeding from the light source (20) proceeds in a lighting direction through the light exit portion (22) and the light entrance portion (21) and thus arrives in the liquid container (3).. .
|Medical test signal generator and interface|
A cardiac signal generator includes a first circuit, a user input device, an output display, and a processing circuit. The first circuit provides, according to any of predetermined plurality of settings, cardiac signals comprising a repeating cardiac waveform, and respiratory signals comprising a repeated respiratory waveform.
|Gas monitoring apparatuses, methods and devices|
This disclosure provides gas monitoring apparatuses, methods and medical devices. A gas monitoring apparatus can include a gas concentration monitoring module, a respiratory mechanics monitoring module and a correction module.
|Combinations comprising antimuscarinic agents and beta-adrenergic agonists|
Combinations comprising (a) a β2 agonist and (b) an antagonist of m3 muscarinic receptors which is 3(r)-(2-hydroxy-2,2-dithien-2-ylacetoxy)-1-(3-phenoxypropyl)-1-azoniabicyclo[2.2.2]octane, in the form of a salt having an anion x, which is a pharmaceutically acceptable anion of a mono or polyvalent acid are useful, e.g., for the treatment of respiratory disease, e.g., asthma or chronic obstructive pulmonary disease.. .
|Pharmaceutical composition for use in nasal administration containing corticoid, and a quinolone or fusidic acid|
The invention relates to a pharmaceutical composition of unit dose for inhalation by a human subject comprising a topical corticoid and a quinolone or fucidic acid, characterized in that the ratio of the weight of the topical corticoid to the weight of the quinolone or fucidic acid is between 0.02 and 20 and the amount of quinolone or of fucidic acid is less than 1 mg. This composition can be administered by nasal spray and is used for treating the upper and lower respiratory tract, in particular sinusitis and nasal polyps..
|Modified rsv f proteins and methods of their use|
The present invention is generally related to modified or mutated respiratory syncytial virus fusion (f) proteins and methods for making and using them, including immunogenic compositions such as vaccines for the treatment and/or prevention of rsv infection.. .
|Method for storing a respiratory mask and respiratory equipment including a respiratory mask and a storage element|
Embodiments provide methods for storing a respiratory mask. In one embodiment, the respiratory equipment may include a respiratory mask having a front side and a rear side and a cavity having an opening in the rear side.
|Harleyhex carbon dioxide balanced foldable respiratory treatment chamber|
One embodiment of a collapsible chamber that is used to house a small animal while administering respiratory medications prescribed by veterinarians that allows atmospheric air to flow in and carbon dioxide to flow out while the animal is receiving respiratory treatment. The chamber: maintains a medically sanitary environment; keeps the animal calm during treatment thus maximizing the amount of medication delivered; becomes foldable, thus portable for mobile treatment or storage; uses standard tubing and connectors for nebulizer, oxygen and other gaseous types of medication delivery systems.
|Method and device for carrying out a signal-processing viewing of a measurement signal that is correlated to the respiratory activity of an individual|
The invention relates to a method and device for carrying out a signal-processing viewing of a measurement signal that is correlated with the respiratory activity of an individual, for example, of a measurement signal that is correlated with the respiratory gas. The aim of the invention is to provide solutions with which an improved electronic analysis of the signals that are representative with regard to respiratory activity can be achieved.
|Systems and methods for quantitative capnogram analysis|
Systems and methods are disclosed herein for quantitatively identifying a patient's physiological state based on one or more capnograms. One or more capnograms are acquired, each capnogram being associated with a patient and including one or more respiratory cycles, and one or more features from the one or more respiratory cycles are extracted.
|Adherent device for respiratory monitoring|
A respiratory monitoring system is provided. A measuring system is provided that includes, (i) an adherent device configured to be coupled to a patient, the adherent device including a plurality of sensors that monitor respiratory status, at least one of the sensors configured to monitor the patient's respiration, and (ii) a wireless communication device coupled to the plurality of sensors and configured to transfer patient data directly or indirectly from the plurality of sensors to a remote monitoring system.
|Nitric oxide donor compounds|
The invention relates to nitric oxide donor compounds and their use for treating cardiovascular diseases, inflammation, pain, fever, gastrointestinal disorders, ophthalmic diseases, hepatic disorders, renal diseases, respiratory disorders, immunological diseases, bone metobolisms dysfunctions, central and peripheral nervous system diseases, sexual dysfunctions, infectious diseases, for the inhibition of platelet aggregation and platelet adhesion, for treating pathological conditions resulting from abnormal cell proliferation, vascular diseases. The invention also relates to compositions comprising at least one nitric oxide releasing compounds of the invention and composition comprising at least one nitric oxide releasing compounds according to the invention and at least one 15 therapeutic agent..
|Composition comprising arabinogalactan and polyphenols from larch trees|
The present invention includes a composition and method of treatment having arabinogalactan and polyphenols from larch trees for the use in prophylactic treatment of upper respiratory tract infections. The invention also includes treatment using such composition..
|Methods and compositions for the treatment of metabolic syndrome, obstructive respiratory disorders, cancer and related diseases|
Compositions comprising igfbp-3 receptor agonists and methods for the treatment of metabolic syndrome, obstructive respiratory disorders, obstructive or inflammatory respiratory disease, cancers and related diseases with igfbp-3 receptor agonists are presented. A method for interfering with the activity of nuclear factor-kappab (nf-kb) in a cell, comprising: providing to a cell an effective amount of a composition comprising an igfbp-3 receptor agonist; and interfering with the activity of nf-kb in the cell is included..
|Combinations of medicaments for the treatment of respiratory diseases|
Wherein the molar ratio of the compound of formula 1 to the active substance 2 is 1:10 to 12:1.. .
|Composition for inhalation|
The invention relates to a formulation comprising formoterol and budesonide for use in the treatment of respiratory diseases. The composition further contains hfa 227, pvp and peg, preferably pvp k25 and peg 1000..