This page is updated frequently with new Respiratory-related patent applications.
|Telocinobufagin (tcino) in the diagnosis and pathogenesis of preeclampsia, traumatic brain injury and acute respiratory distress syndrome|
Certain embodiments are directed to methods of identifying patients with pe, tbi, or ards by detecting elevated levels of mbg, tcino, and cino and treating the same with anti-mbg agents.. .
|High flow therapy artificial airway interfaces and related methods|
Embodiments of the present invention provide a device, system and method for providing high flow therapy interfaces for use in the treatment of respiratory conditions and in assisted respirations. A nasal cannula for delivery of respiratory gases includes at least one nasal insert and at least one flange coupled to the at least one nasal insert where the at least one flange extends in a radial direction from the at least one nasal insert is provided.
Mergenet Medical, Inc.
|Immunogenic composition for mers coronavirus infection|
Described herein are immunogenic compositions for preventing infection with middle east respiratory syndrome coronavirus (mers-cov) wherein the immunogenic compositions comprise at least a portion of the mers-cov s protein and an immunopotentiator.. .
New York Blood Center, Inc.
|Polyinosinic-polycytidylic acid (poly (i:c)) formulations for the treatment of upper respiratory tract infections|
The present invention concerns a composition comprising micro particles of polyinosinic-polycytidylic acid (poly (i:c)) and a carrier polymer selected from starch, alginate, blanose or dppc (dipalmitoylphosphatidylcholine) for use in preventing and/or treating viral infections of the upper respiratory tract or the common cold and a device, preferably a nasal delivery system, comprising said composition for use by a patient in need to prevent and/or treat infections or the common cold.. .
|P2x3 and/or p2x2/3 compounds and methods|
The present application provides novel compounds and methods for preparing and using these compounds. In one embodiment, the compounds are of the structure of formula (i), wherein r1-r4 are defined herein.
Asana Biosciences, Llc
|Methods of inducing sedation|
The present invention provides methods for determining the selectivity of a sedative for an anesthetic-sensitive receptor by determining the molar water solubility of the sedative. The invention further provides methods for modulating the selectivity of a sedative for an anesthetic-sensitive receptor by altering or modifying the sedative to have higher or lower water solubility.
The Regents Of The University Of California
|Multi-cycle dynamic ct imaging|
A dynamic ct imaging method is provided. With the method, projection measurement data for a region of an examination object to be imaged is captured, with simultaneous correlated capture of the respiratory movement of the examination object.
|Extended wear electrocardiography and respiration-monitoring patch|
Physiological monitoring can be provided through a wearable monitor that includes two components, a flexible extended wear electrode patch and a removable reusable monitor recorder. The wearable monitor sits centrally (in the midline) on the patient's chest along the sternum oriented top-to-bottom.
Bardy Diagnostics, Inc.
|Adaptive user interface based on health monitoring event|
Collecting biometric data from a patient provides numerous opportunities for a care provider to monitor the health of the patient. In one embodiment, the biometric data is used to identify health events that are processed in a workflow that includes a plurality of interconnected tasks and queues.
|System and neuromorphic controlled adaptive pacing of respiratory muscles and nerves|
Adaptive systems and methods for automatically determining and continuously updating stimulation parameters for adjusting ventilation to accommodate a patient's specific physiology, metabolic needs, and muscle state are disclosed herein. Having a closed loop implementation, the system may comprise a controller including a neuromorphic controlled adaptive feed-forward pattern generator/pattern shaper (pg/ps) assembly, which controls respiratory muscle movement using electrical stimulation.
The Florida International University Board Of Trustees
Systems and methods for patient-proximate vapor transfer for respiratory therapy
Systems, methods, and devices for humidifying a breathing gas are presented. The system includes a source of pressurized breathing gas, a vapor transfer unit external to the source of pressurized breathing gas, a first gas tube connecting the source of pressurized breathing gas to the gas inlet of the vapor transfer unit and having a first length, a liquid supply having a heater that heats liquid, a first liquid tube coupling the liquid supply to the liquid inlet of the vapor transfer unit, and a second gas tube having a second length and connecting the gas outlet to a patient interface.
System and determining position of a medical device
A system for determining a position of a medical device in a respiratory system of a patient is provided. The system includes a positioning apparatus, a flexible guide rod having a distal portion, the flexible guide rod configured to be inserted into a passage of the respiratory system of the patient through the positioning apparatus, and an emitter coupled to the distal portion of the flexible guide rod.
P Tech, Llc
Systems and methods for detection of respiratory events using pattern recognition
Various embodiments of the present invention provide systems, methods and devices for respiratory support. As one example, a method is described that includes providing a measured signal such as gas pressure or flow or any respiratory signal derived or obtained by combining pressure or flow signals related to a patient's breathing.
This invention provides kits, devices, and methods for the detection of antibodies that recognize one or more proteins and/or antigens from porcine reproductive and respiratory syndrome virus (prrsv). The antibodies may be in a biological fluid of a prrsv infected or at risk subject.
Regents Of The University Of Minnesota
Vaccine to protect a ruminant against pneumonia caused by mannheimia haemolytica
The present invention pertains to a vaccine for administration to the upper respiratory tract of a ruminant to protect said ruminant against pneumonia caused by mannheimia haemolytica, the vaccine comprising in combination live attenuated mannheimia haemolytica bacteria, live attenuated parainfluenza-3 virus and live attenuated bovine respiratory syncytial virus, wherein the vaccine is for administration to the upper respiratory tract of the ruminant via intranasal atomisation of the vaccine.. .
Aerosol fluoroquinolone formulations for improved pharmacokinetics
The present invention relates to the field of antimicrobial agents. In particular, the present invention relates to the use of aerosolized fluoroquinolones formulated with divalent or trivalent cations and having improved pulmonary availability for the treatment and management of bacterial infections of the lung and upper respiratory tract..
Raptor Pharmaceuticals Inc.
Combinations of medicaments for the treatment of respiratory diseases
Wherein the molar ratio of the compound of formula 1 to the active substance 2 is 1:10 to 12:1.. .
Cough containment apparatus
A laminated, antiviral and silver impregnated, 100% activated woven carbon cloth is fashioned into a biodegradable disposable device. The device has the ability to capture and kill viruses, germs and bacteria that emanate from the cough as one suffers the effects of respiratory infections.
Respiratory therapy instrument offering game-based incentives, training, and telemetry collection
A respiratory therapy instrument providing a telehealth platform for pulmonary care includes a housing with opposed extension arms, an airway tube removably clamped between the opposed extension arms, a pair of pressure sensors, and a circuit board retained within the housing. The pressure sensors are in communication with an interior of the airway tube and are configured to detect pulmonary flow data within the airway tube.
Compliant Games, Inc.
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Detection of periodic breathing
Methods and apparatus perform periodic breathing detection, such as cheyne-stokes respiration detection. The detection may be performed by one or more processors, such as by analysis of data from one or more sensors.
Resmed Sensor Technologies Limited
Plethysmographic respiration processor
A plethysmographic respiration processor is responsive to respiratory effects appearing on a blood volume waveform and the corresponding detected intensity waveform measured with an optical sensor at a blood perfused peripheral tissue site so as to provide a measurement of respiration rate. A preprocessor identifies a windowed pleth corresponding to a physiologically acceptable series of plethysmograph waveform pulses.
Gene transfer into airway epithelial stem cell by using lentiviral vector pseudotyped with rna virus or dna virus spike protein
The present inventors successfully introduced genes into stem cells of airway epithelial tissues using simian immunodeficiency virus vectors pseudotyped with f and hn, which are envelope glycoproteins of sendai virus. Gene transfer into airway epithelial tissue stem cells using a vector of the present invention is useful for gene therapy of genetic respiratory diseases such as cystic fibrosis.
Id Pharma Co., Ltd.
Compositions and methods of use of interleukin-10 peptides and anti-interleukin-10 antibodies
Disclosed herein are methods of reducing a symptom of respiratory disease in a pre-weaned milk-fed mammal by orally administering an isolated antibody that specifically binds the interleukin-10 peptide or an anti-interleukin-10 antibody. Also included are methods of reducing mixing stress in human and non-human mammals by administering an isolated antibody that specifically binds the interleukin-10 peptide or an anti-interleukin-10 antibody.
Wisconsin Alumni Research Foundation
Nasal mask system
An elbow for a respiratory mask includes a mask connection end adapted to connect to the mask and a tube connection end adapted to connect to an air delivery tube that delivers breathable gas to a patient. The mask connection end includes a first region constructed of a more rigid material and a second region constructed of a more flexible material.
Detection of asynchrony
A controller or processor(s) implements detection of respiratory related conditions, such as asynchrony, associated with use of a respiratory treatment apparatus or ventilator. Based on data derived from sensor signals associated with the respiratory treatment, the detector may evaluate a feature set of detection values to determine whether or not an asynchrony occurs in a breath of the patient's respiratory cycle such as by comparing the values against a set of thresholds.
Inductive breathing mask and respiratory care system thereof
An inductive breathing mask is provided, which comprises a covering shell, a mask pad, and a pressure inductive unit, wherein the pressure inductive unit comprising at least one pressure inductive part, and the pressure inductive part is disposed on the mask pad where corresponds to at least one of the user's nasion, left cheek beside nose, right cheek beside nose, and chin for detecting the pressure of the user's nasion, left cheek beside nose, right cheek beside nose, and chin generated by the mask pad. In addition, the inductive breathing mask of the present invention may further be integrated with other functional elements for constructing a respiratory care system having warning and/or monitoring functions..
Taichung Veterans General Hospital
Portable high frequency ultrasonic nebulizer for the whole respiratory tract drug delivery
A nebulizer composed of shell with air inlet and lid with spray nozzle. Inside the shell, lays, from bottom to top, a drug cup with piezoelectric transducer and spray chamber with spray outlet.
Guangzhou Nanotides Pharmaceuticals Co., Ltd.
Compositions and methods for enzymatic treatment of lung disorders
A therapeutic composition for the treatment of lung diseases or disorders and diseases or disorders of the airway passages including pneumonia, acute respiratory failure, and acute respiratory distress syndrome is based on the generation of a biocidal anion by an enzymatic reaction catalyzed by a peroxidase. The peroxide utilized by the peroxidase enzyme can be endogenous or can be generalized by the action of an oxidase enzyme on a suitable substrate..
Pulse inhalation of nitric oxide for treating respiratory diseases
A method of treating a human subject which is effected by intermittent breathing cycle-coordinated pulse delivery inhalation of gaseous nitric oxide at a concentration of at least 160 ppm, or at a load per cycle of 80 ppm-hour, is disclosed. The method can be utilized for treating a human subject suffering from, or prone to suffer from, a disease or disorder that is manifested in the respiratory tract, or from a disease or disorder that can be treated via the respiratory tract.
Advanced Inhalation Therapies (ait) Ltd.
Textile piezoresistive sensor and heartbeat and/or respiratory rate detection system
The invention relates to a piezoresistive textile sensor for detecting the heart and respiratory rate, comprising a lower textile layer whereon a conductive ink or paste is deposited such that first conductive strips are defined, said lower textile layer being joined to a second piezoresistive textile layer whereon a second conductive strip is arranged, to which an upper textile layer is then joined, on which conductive inks and/or pastes can be deposited, said piezoresistive textile sensor being used in a system for detecting the heart and/or respiratory rate.. .
Sensing Tex, S.l.
Epidermal sensor system and process
Epidermal electronics are sensors with mechanical properties matching human epidermis. Their manufacturing process includes photolithography and dry and wet etching within cleanroom facilities.
Board Of Regents, The University Of Texas System
Compositions comprising a biological control agent and a fungicide from the group consisting of inhibitors of the respiratory chain at complex i or ii
The present invention relates to a composition comprising at least one biological control agent. Furthermore, the present invention relates to the use of this composition as well as a method for reducing overall damage of plants and plant parts..
Bayer Cropscience Ag
Serum/plasma micrornas and uses thereof
This invention provides a combination of micrornas for evaluating the physiological and/or pathological condition of a subject, wherein the combination comprises all detectable micrornas stably existing in the serum/plasma of a subject; and a method for evaluating the physiological and/or pathological condition of a subject, wherein the method includes determining all detectable micrornas stably existing in the serum/plasma of a subject; and a kit for evaluating the physiological and/or pathological condition of a subject, wherein the kit contains the tools for determining all detectable micrornas that stably existing in the serum/plasma of a subject; and a biochip for evaluating the physiological and/or pathological condition of a subject, wherein the biochip contains the components for determining all detectable micrornas stably existing in the serum/plasma of a subject. The aforementioned combination, method, kit and biochip can be used for diagnosis as well as differentially diagnosis of diseases including various tumors; various acute/chronic infectious diseases, e.g.
Jiangsu Mingma Biotech Co., Ltd.
Respiratory syncytial virus inhibitors
Compounds of formula (i), wherein r1, r2, r3, r4 and n are defined herein, are useful as inhibitors of rsv.. .
Delivery of respiratory gases
A respiratory system provides conditioned respiratory gases to a patient within a controlled temperature environment. A humidification apparatus has an inspiratory tube that may extend to a patient interface.
Fisher & Paykel Healthcare Limited
Methods of using inhaled nitric oxide gas for treatment of acute respiratory distress syndrome in children
The present invention provides a treatment of acute respiratory distress syndrome (ards) in children using dosing of nitric oxide at low concentrations, such as less than 10 ppm.. .
Mallinckrodt Hospital Products Ip Limited
System and administering a pharmaceutical gas to a patient
Described are methods and systems for delivering a pharmaceutical gas to a patient. The methods and systems provide varying quantities of pharmaceutical gas delivered to the patient in two or more breaths based on the monitored respiratory rate or changes in the patient's respiratory rate.
Mallinckrodt Hospital Products Ip Limited
Polylnosinic-polycytidylic acid (poly (i:c)) formulations for the treatment of upper respiratory tract infections
The present invention concerns a composition comprising micro particles of polyinosinic-polycytidylic acid (poly (i:c)) and a carrier polymer selected from the group pea starch, pregelatinized potato starch, lactose, microcrystalline cellulose, hyaluronate or glucosamine for use in preventing and/or treating viral infections of the upper respiratory tract or the common cold and a device, preferably a nasal delivery system, comprising said composition for use by a patient in need to prevent and/or treat infections or the common cold.. .
Janssen Sciences Ireland Uc
Methods of using diaminopyrimidine p2x3 and p2x2/3 receptor modulators for treatment of respiratory and gastrointestinal diseases
Wherein d, x, y, r1, r2, r3, r4, r5, r6, r7 and r8 are as defined herein.. .
Alternating sympathomimetic therapy for the treatment of respiratory ailments
A combination of dosage units for alleviating respiratory ailments and a method of alleviating respiratory ailments which uses this combination of dosage units. The dosage units comprise one or more first dosage units comprising pseudoephedrine and/or a pharmaceutically acceptable salt thereof and one or more second dosage units comprising phenylephrine and/or a pharmaceutically acceptable salt thereof..
Sovereign Pharmaceuticals, Llc
System and classifying respiratory and overall health status of an animal
Systems and methods are provided for determining the respiratory and overall health status of an animal. The systems and methods utilize location data of individual animals to generate variables describing the behavior of the individual animals.
Precision Animal Solutions, Llc
Human monoclonal antibodies against the middle east respiratory syndrome coronavirus (mers-cov) and engineered bispecific fusions with inhibitory peptides
The invention provides polypeptides (e.g., antibodies) and fusion proteins that target a epitope in the receptor binding domain (rbd) of the spike (s) glycoprotein of the middle east respiratory syndrome coronavirus (mers-cov). The polypeptides and fusion proteins can be used to treat and prevent mers-cov infection in mammals..
The University Of Hong Kong
4'-vinyl substituted nucleoside derivatives as inhibitors of respiratory syncytial virus rna replication
Wherein the variable substituents are as defined herein. The compounds of formula i and pharmaceutical compositions comprising compounds of formula i are useful for the treatment of diseases mediated by rsv..
Azido nucleosides and nucleotide analogs
Disclosed herein are nucleosides, nucleotides and analogs thereof, pharmaceutical compositions that include one or more of nucleosides, nucleotides and analogs thereof, and methods of synthesizing the same. Also disclosed herein are methods of ameliorating and/or treating a disease and/or a condition, including an infection from a paramyxovirus and/or an orthomyxovirus, with a nucleoside, a nucleotide and an analog thereof.
Alios Biopharma, Inc.
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And to compositions comprising the same and to the use of the compounds and their compositions in treatment, for example in the treatment of inflammatory diseases, in particular respiratory inflammatory disease. The invention also extends to methods of making said compounds..
New cyclohexylamine derivatives having ß2 adrenergic agonist and m3 muscarinic antagonist activities
The present invention relates to novel compounds having β2 adrenergic agonist and m3 muscarinic antagonist dual activity, to pharmaceutical compositions containing them, to the process for their preparation and to their use in respiratory therapies.. .
Mask for the respiratory therapy with dedicated access for a nasogastric tube
A mask for the respiratory therapy with dedicated access for a nasogastric tube comprising a shaped shell (12) at least covering mouth, nose and eyes of a patient (11), and provided, along a perimeter (13) which is suitable for being placed in contact against the patient's face, with a sealing gasket (14), said shaped shell (12) being provided with at least one inlet fitting (15) for the mixture of air and oxygen, said mask also comprising a neckpiece (20) provided with a plurality of prongs (21), each joined in a fixed or removable manner to a corresponding fastening point (17), distributed over the perimeter (13) of the shaped shell (12), is provided with a pneumatic-sealed dedicated access (30) for a nasogastric tube (31), wherein the shaped shell (12) bears a hole (32) having sufficient dimensions for the passage of the end of the nasogastric tube.. .
Seal mask for the respiratory therapy
An improved-seal mask for the respiratory therapy of the type comprising a shaped shell (12) at least covering mouth, nose and eyes of a patient (11), and provided, along a perimeter (13) which is suitable for being placed in contact against the patient's face, with a sealing gasket (14), said shaped shell (12) being provided with at least one inlet fitting (15) for the mixture of air and oxygen, said mask also comprising a neckpiece (20) provided with a plurality of prongs (21), each joined in a fixed or removable manner to a corresponding fastening point (17), distributed over the perimeter of the shaped shell (12), is provided with five fastening points (17) for the neckpiece (20), wherein two upper fastening points (17′) are arranged at the height of the eyes, symmetrically with respect to a sagittal plane, two lower fastening points (17″) are arranged at the height of the chin, symmetrically with respect to a sagittal plane, and a fifth fastening point (17′″) is arranged centrally along an upper edge (18) of the mask suitable for resting on the forehead, namely in the sagittal plane.. .
Improved the administration of a pulmonary surfactant by atomization
The system allows optimizing the dispensing of aerosol medicaments. In particular the system allows the administration of an exogenous pulmonary surfactant to very young patients (e.g.
Chiesi Farmaceutici S.p.a.
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Nasal douche with valve that can be actuated by respiratory air
A nasal douche having a valve, container part and cap part, wherein the container part serves to receive irrigation liquid and carries cap part. The cap part has a nose attachment with an outlet opening for irrigation liquid connected fluidically to interior of container part via discharge channel, wherein nose attachment is intended to be attached to a nostril of the user.
Formulations useful in the treatment of proliferative diseases affecting the respiratory tract
The present application provides a pharmaceutical formulation comprising a folate receptor (fr)-targeting antineoplastic substance or composition, wherein the pharmaceutical formulation is configured for administration by inhalation, wherein the fr-targeting antineoplastic substance or composition is comprised in a nanoparticle and wherein the nanoparticles are comprised in microparticles, and its use in the treatment of a proliferative disease affecting at least part of the respiratory tract. The present application further provides a pharmaceutical formulation comprising an antineoplastic agent and a fr-targeting excipient, for use in the treatment of a proliferative disease affecting at least part of the respiratory tract..
Universite Libre De Bruxelles
P13k inhibitor for treatment of respiratory disease
The present invention is directed to compounds and pharmaceutically acceptable salts thereof which are inhibitors of the activity or function of the phosphoinositide 3′oh kinase family (hereinafter pi3k) for use in the treatment or prevention of respiratory infections, the treatment of airway damage, and/or the prevention of airway injury in patients.. .
Glaxosmithkline Intellectual Property Development Limited
Aclidinium for use in improving the quality of sleep in respiratory patients
The present disclosure provides aclidinium or any of its stereoisomers or mixture of stereoisomers, or a pharmaceutically acceptable salt or solvate thereof, for improving the quality of sleep in respiratory patients.. .
An avian tincture composition and associated methods for producing the same for treatment of the avian species with the avian tincture. The avian tincture may be used in the treatment of abscesses, inflamed and swollen leg joints, respiratory issues, wounds, infection, and acute disease or parasite overload conditions..
Systems and methods to increase survival with favorable neurological function after cardiac arrest
A system includes a guidance device that provides feedback to a user to compress a patient's chest at a rate of between about 90 and 110 compressions per minute and at a depth of between about 4.5 centimeters to about 6 centimeters. The system includes a pressure regulation system having a pressure-responsive valve that is configured to be coupled to a patient's airway.
Advanced Circulatory Systems, Inc.
Respiratory effect reduction in catheter position sensing
A method, including positioning body-electrodes in galvanic contact with a body of a patient and locating a probe in the body of the patient. The method further includes tracking positions of the probe during respiration of the patient and determining indications related to impedances between the body-electrodes during the respiration.
Biosense Webster (israel) Ltd.
Improved oxygenating apparatus
A disposable oxygenation apparatus used to apply an oxygen enriched, positive pressure to a patient's airway where a respiratory device is in situ or is to be used, to decrease the incidence of desaturation and with an lma in situ to assist in maintaining the patient's vocal cords open during recovery after anaesthesia. The apparatus includes a passageway or passageways extending therethrough, an expiratory valve or valves located in or adjacent an outlet for controlling the passage of expired air from said patient during expiration, a primary inspiratory valve located in or adjacent a primary inlet, for controlling oxygen or oxygen rich air flowing through the passageway or passageways from a collapsible reservoir bag, and a secondary inspiratory valve located in or adjacent a secondary inlet for controlling entry of ambient air in from an exterior of the apparatus during inspiration when the collapsible reservoir bad has been substantially emptied..
Wallis Coombe Pty Ltd As Trustee For Sleuky Family Trust
Control for pressure of a patient interface
A method of an apparatus control pressure in the patient interface. A vent valve may be used with a respiratory device, where the vent valve may selectively block fluid communication between components, such as the flow generator, the patient interface, and/or the vent.
Systems and methods for heating and humidifying inspired gases during mechanical ventilation
Systems and methods for heating and/or humidifying a respiratory gas or gas mixture delivered to a human or animal patient during spontaneous or mechanical ventilation.. .
Humidifier for respiratory apparatus
A flexible tape heater (110) in a patient conduit (112) may be used to heat the flow of gas in the patient conduit (112) that is delivered to the patient mask (116). The thin, flat and extended nature of the flexible tape heater (110) may enhance heat transfer with the gas flow whilst also providing low impedance to the gas flow.
Breathing assistance apparatus
Breathing assistance apparatus for treating sleep apnoea are described. More specifically, nasal interface for the supply of respiratory gases, but most particularly positive pressure gases are described.
Fisher & Paykel Healthcare Limited
Systems and methods for selectively blocking respiratory air flow
Systems, devices and methods for selectively blocking respiratory air flow to portions of a lung are disclosed. For example, one bronchus of a lung may be sealed off while another bronchus remains open to air flow.
Methods and devices for the detection of hypopnoea
Automated methods provide hypopnea detection for determining a hypopnea event and/or a severity of a hypopnea event. In some embodiments, a calculated short-term variance of a measured respiratory flow signal are compared to first and second proportions of a calculated long-term variance of the measured flow signal.
The present invention concerns a neuroglobin agonist for use in the treatment or prevention of a mitochondrial disease associated with respiratory chain complex i (rcci) deficiency and/or respiratory chain complex iii (rcciii) deficiency.. .
Institut National De La Sante Et De La Recherche Medicale (inserm)
Prrsv gp5 based compositions and methods
The disclosure includes compositions and methods for the production of an immune response against porcine reproductive and respiratory syndrome (prrs) virus, or prrsv. The disclosure is based in part on the use of two or more peptide domains, each with a different sequence, from the prrsv gp5 protein ectodomain.
Mj Biologics, Inc.
Pi3k inhibitor for treatment of respiratory disease
The present invention is directed to compounds and pharmaceutically acceptable salts thereof which are inhibitors of the activity or function of the phosphoinositide 3′oh kinase family (hereinafter pi3k) for use in the treatment or prevention of respiratory infections, the treatment of airway damage, and/or the prevention of airway injury in patients with a pi3kδ mutation.. .
Glaxosmithkline Intellectual Property Development Limited
Novel compounds as respiratory stimulants for treatment of breathing control disorders or diseases
The present invention includes a composition comprising a compound, such as a 2,4,6-triamino-1,3,5-triazine, 2,4,6-triaminopyrimidine, 2,4-diamino-6,7-dihydro-5h-pyrrolo[2,3-d]pyrimidine or 2,4-diamino-7h-pyrrolo[2,3-d]pyrimidine, that is useful in the treatment of breathing control diseases or disorders in a subject in need thereof. The present invention also includes a method of treating a respiratory disease or disorder in a subject in need thereof, comprising administering to the subject a therapeutically effective amount of a pharmaceutical composition of the invention.
Galleon Pharmaceuticals, Inc.
Methods for treating or preventing acute vascular leak
The invention features methods, devices, pharmaceutical compositions, and kits for treating or preventing acute vascular leak. Such methods may involve contacting an effective amount of bosutinib for treating or preventing acute vascular leak with a subject in need thereof.
The Brigham And Women's Hospital, Inc.
Compositions and methods for treatment of respiratory tract infections
This invention teaches a novel treatment of patients infected with influenza virus in early stages of the disease, with liposomes called α-gal/sa liposomes, in order to decrease the infection period and decrease further complications by this disease. The treatment is based on inhalation of biodegradable liposomes that present two types of carbohydrate epitopes: α-gal epitopes with the structure galα1-3galβ1-4(3)glcnac-r) and sialic acid (sa) epitopes.
Alertness device, seat, and determining alertness
An alertness device includes: a respiration sensor that obtains respiratory data of a person; a calculation unit; a waveform generation unit that generates a respiratory interval (ri) waveform which is a transition in a predetermined time period of an ri which is an interval for one respiration; and a determination unit. The calculation unit calculates an average value of the ri and rrmssdn in a predetermined time period.
Public University Corporation Nagoya City University