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Receptor

Receptor-related patent applications - as published by the U.S. Patent and Trademark Office (USPTO).


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Wireless power feeding method and wireless power feeding device
Panasonic Corporation
December 07, 2017 - N°20170353052

A wireless power feeding method includes causing each of a plurality of power transmitters to acquire power amounts for power received by one or more of a power receptors which are targets for power transmission, determining a first power amount which is the smallest out of acquired power amounts, and adjusting a power transmission direction to be a direction in ...
Systems and methods for treating, diagnosing and predicting the occurrence of a medical condition
Fundação D. Anna De Sommer Champalimaud E Dr. Carlos Montez Champalimaud,dba Champalimaud Fnd.
December 07, 2017 - N°20170351837

Clinical information, molecular information and/or computer-generated morphometric information is used in a predictive model for predicting the occurrence of a medical condition. In an embodiment, a model predicts whether a patient is likely to have a favorable pathological stage of prostate cancer, where the model is based on features including one or more (e. G., all) of preoperative psa, ...
Image forming apparatus
Fuji Xerox Co., Ltd.
December 07, 2017 - N°20170351210

An image forming apparatus includes: an electrophotographic photoreceptor that includes an electroconductive substrate, an undercoat layer which is provided on the electroconductive substrate and has electrostatic capacitance per unit area of from 2. 5×10−11 f/cm2 to 2. 5×10−10 f/cm2, and a photosensitive layer provided on the undercoat layer; a charging unit; an electrostatic latent image forming unit; a ...
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Synthetic receptors for hydrosulfide
Canon Kabushiki Kaisha
December 07, 2017 - N°20170350870

R3; r5; r7; r9 and r10 are each independently selected from h, substituted lower alkyl, lower alkyl, substituted aralkyl, aralkyl, substituted aryl or aryl.
Lightning system for wind turbine blades with optimized means for injecting lightning currents in conductive ...
Gamesa Innovation & Technology, S.l.
December 07, 2017 - N°20170350374

The invention provides a lightning protection system for wind turbine blades with optimized injection means of lightning currents in conductive components of their shells. The injection means comprise a current receptor element (27; 47; 67) connected to the input cable of lightning currents and arranged over an area of a shell close to an electrically conductive component (22; 42; 62) and a current injection element (28; 48; 68; 69, 69′) ...
Methods for detecting enhanced nmda receptor function and uses thereof
Inova Health System
December 07, 2017 - N°20170349943

A method of determining the risk of cognitive decline in an aging subject is provided. The method includes analyzing an mrna transcript including a grin2b nucleic acid sequence for the presence of the a allele in a biological sample obtained from the subject. The method also includes identifying the subject as having a decreased risk of cognitive decline when ...
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C-met antibody combinations
Argenx Se
December 07, 2017 - N°20170349667

The invention provides a product combination or composition, and also multispecific antibodies comprising two or more antigen-binding sites (as antibodies or antigen binding fragments thereof), wherein two the antigen-binding bind to distinct non-overlapping epitopes of the human c-met protein. The product combination or composition or multispecific antibody inhibits hgf-independent activation of the human c-met receptor protein.
Use of il-20 antagonists for treating pancreatic cancer
National Cheng Kung University
December 07, 2017 - N°20170349656

Methods for treating pancreatic cancer using an il-20 antagonist, which can be an antibody that binds il-20 or an il-20 receptor, thereby blocking the signaling pathway mediated by il-20.
Compositions and methods of treating disease with fgfr fusion proteins
Five Prime Therapeutics, Inc.
December 07, 2017 - N°20170349643

The invention provides fgfr fusion proteins, methods of making them, and methods of using them to treat proliferative disorders, including cancers and disorders of angiogenesis. The fgfr fusion molecules can be made in cho cells and may comprise deletion mutations in the extracellular domains of the fgfrs which improve their stability. These fusion proteins inhibit the growth and viability of ...
Glucagon/glp-1 receptor co-agonists
Indiana University Research And Technology Corporation
December 07, 2017 - N°20170349642

Provided herein are peptides and variant peptides that exhibit enhanced activity at the glp-1 receptor, as compared to native glucagon.
Angiotensin-1-receptor antagonists
Indiana University Research And Technology Corporation
December 07, 2017 - N°20170349629

In which aa1, aa4, aa5, and aa8 are defined in the specification. The compounds of formula (i) can be used to treat hypertension (e. G., hypertension induced by pregnancy), preeclampsia, or a renal disease induced by pregnancy.
Imidazopyrimidine and imidazotriazine derivative, and pharmaceutical composition comprising the same
Indiana University Research And Technology Corporation
December 07, 2017 - N°20170349597

The compound of chemical formula (1) or pharmaceutically acceptable salt thereof acts as a positive allosteric modulator of metabotropic glutamate receptor subtype 5 (mglur5), thereby being useful in the prevention or treatment of disorder mediated by glutamate dysfunction and mglur5.
8-azabicyclo[3.2.1]octane compounds as mu opioid receptor antagonists
Indiana University Research And Technology Corporation
December 07, 2017 - N°20170349578

Wherein r1, r2, r3, a, and g are defined in the specification, or a pharmaceutically-acceptable salt or solvate thereof, that are antagonists at the mu opioid receptor. The invention also provides pharmaceutical compositions comprising such compounds, methods of using such compounds to treat conditions associated with mu opioid receptor activity, and processes and intermediates useful for preparing such compounds.
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Positive allosteric modulators of human melanocortin-4 receptor
Glaxo Group Limited
December 07, 2017 - N°20170349571

Disclosed herein are positive allosteric modulators of melanocortin receptor and methods of using such modulators.
5-ht2b antagonists
Glaxo Group Limited
December 07, 2017 - N°20170349559

And related methods for treating a person having a disorder characterized by undesirable 5-ht2b receptor signaling, such as migraine, irritable bowel syndrome (ibs), pulmonary arterial hypertension (pah), fibrosis, hepatocellular cancer, a small intestinal neuroendocrine tumor, cardiovascular disorders, and gastrointestinal (gi) tract disorders.
Compositions and methods for treating neurodegenerative disease
Cognition Therapeutics, Inc.
December 07, 2017 - N°20170349554

This invention relates to the use sigma-2 receptor antagonists, and of pharmaceutical compositions comprising such compounds, in methods for inhibiting abeta-associated synapse loss or synaptic dysfunction in neuronal cells, modulating an abeta-associated membrane trafficking change in neuronal cells, and treating cognitive decline associated with abeta pathology and more broadly treating with such compounds and compositions neurodegenerative diseases and disorders associated ...
Hydroxyl compounds and compositions for cholesterol management and related uses
Esperion Therapeutics, Inc.
December 07, 2017 - N°20170349516

The present invention relates to novel hydroxyl compounds, compositions comprising hydroxyl compounds, and methods useful for treating and preventing a variety of diseases and conditions such as, but not limited to aging, alzheimer's disease, cancer, cardiovascular disease, diabetic nephropathy, diabetic retinopathy, a disorder of glucose metabolism, dyslipidemia, dyslipoproteinemia, hypertension, impotence, inflammation, insulin resistance, lipid elimination in bile, obesity, oxysterol elimination ...
Apparatus, method, and system for providing tunable circadian lighting at constant perceived brightness and color
Musco Corporation
December 07, 2017 - N°20170348506

The newly discovered retinal ganglion cell photoreceptor melanopsin absent in the central fovea of the eye but distributed throughout the remaining human retinal body provides both non-visual biological/physiological input inducing circadian entrainment, and visual input affecting perceived brightness; this perceived brightness is not the object brightness commonly associated with luminance and perceived color of an object in central view, ...
Compositions and methods for detecting ccr2 receptors
Washington University
December 07, 2017 - N°20170348442

Among the various aspects of the present disclosure is the provision of compositions of imaging agents and methods for use in detecting, monitoring, and evaluating ccr2 associated diseases, disorders, and conditions.
Non-cleavable polymer conjugated with alpha v beta 3 integrin thyroid antagonists
Nanopharmaceuticals, Llc
December 07, 2017 - N°20170348425

Chemical compositions and methods of synthesis thereof. The compositions disclosed and described herein are directed toward and classified as anti-angiogenic thyrointegrin antagonists, which may be capable of reacting with one or more cell surface receptors of the integrin αvβ3 receptor family. Anti-angiogenic thyrointegrin antagonists or derivatives thereof are conjugated via a non-cleavable linker having an amine, ...
Tfr selective binding compounds and related methods
Ossianix, Inc.
December 07, 2017 - N°20170348416

The present invention relates to peptides that bind with high specificity and which functionally interact with the transferrin receptor (“tfr”) and which may be used in making molecular vehicles that carry biomolecules across membranes, including, e. G., across the blood brain barrier or the gastrointestinal tract. Tfr specific binding moieties may also be used alone or ...
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