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Reagent patents

      

This page is updated frequently with new Reagent-related patent applications.




 Diagnostic cassette patent thumbnailDiagnostic cassette
A diagnostic cassette includes a substrate, to physically and electrically connect the product to a computing device, a reservoir defined within the substrate to receive a fluid sample for processing by the diagnostic cassette, a reagent to react with the fluid sample deposited in the reservoir to form a solution to enable processing of the fluid sample by the diagnostic cassette, a channel to direct the solution, and a sensor to measure a number of parameters of the solution passing through the channel. A method for measuring microfluidic samples includes receiving, in a reservoir, a fluid sample to be measured, combining the fluid sample with a reagent to create a solution, moving the solution through a channel, and measuring the solution, using sensors, as the solution passes through the channel..
Hewlett-packard Development Company, L.p.


 Gas-phase deposition process patent thumbnailGas-phase deposition process
The disclosure relates to a layer-deposition process that includes: injecting a first reagent in gaseous phase into the deposition chamber via a first injection path, and injecting a second gas-phase reagent into the deposition chamber via a second injection path, the second injection path being separate from the first injection path. The pressure in the deposition chamber is greater than a predetermined value for the entire duration of the process.
Altatech Semiconductor


 Method of synthesizing nucleic acid patent thumbnailMethod of synthesizing nucleic acid
An oligonucleotide having a novel structure and a method of synthesizing nucleic acid uses the same as a primer. This oligonucleotide is provided at the 5′-side of the primer with a nucleotide sequence substantially the same as a region synthesized with this primer as the origin of synthesis.
Eiken Kagaku Kabushiki Kaisha


 Nucleic acid amplification reagent, nucleic acid amplification cartridge, and nucleic acid amplification method patent thumbnailNucleic acid amplification reagent, nucleic acid amplification cartridge, and nucleic acid amplification method
A nucleic acid amplification reagent includes a first probe which anneals to a target nucleic acid in a region sandwiched between a site to which the 3′ end of a forward primer anneals and a site to which the 3′ end of a reverse primer anneals in a template nucleic acid, and a second probe which anneals to a nucleic acid other than the target nucleic acid in the region. Each of the first probe and the second probe includes a dye which emits light in a wavelength band mutually overlapping partially..
Seiko Epson Corporation


 Expansion and engraftment of stem cells using notch 1 and/or notch 2 agonists patent thumbnailExpansion and engraftment of stem cells using notch 1 and/or notch 2 agonists
The present disclosure provides methods for immortalizing precursor cells that are non-terminally differentiated cells such as stem cells, the methods comprising culturing the precursor cells in the presence of a notch 1 agonist, notch 2 agonist or notch 1 agonist and notch 2 agonist (and, in particular embodiments, one or more growth factors) that support the proliferation but not differentiation of the non-terminally differentiated cells. The present disclosure further provides methods to induce the differentiation of immortalized cells, comprising growing the cells in the presence of a notch 1 agonist, notch 2 agonist or notch 1 agonist and notch 2 agonist and at least one growth factor which supports the differentiation of the cell into a more specialized cell type.
Fred Hutchinson Cancer Research Center


 Site specific protein modifications patent thumbnailSite specific protein modifications
The present invention relates to method and reagents for use in site-selective modification of protein and peptide. The site selective modification is a selective derivation of the amino functionality at the n-terminus of the protein or the polypeptide using the presence of a neighboring histidine amino acid to increase the reactivity of the n-terminal amino functionality.
Novartis Ag


 Windows for display device and display device including the same patent thumbnailWindows for display device and display device including the same
A window for a display device including: a plastic substrate including a poly(imide-amide) copolymer, which is a reaction product of a reagent combination of 4,4′-hexafluoroisopropylidene diphthalic anhydride, 3,3′,4,4′-biphenyltetracarboxylic dianhydride, 2,2′-bis-trifluoromethyl-4,4′-biphenyldiamine, and terephthaloyl chloride, and a hard coating layer disposed on at least one side of the plastic substrate, wherein the plastic substrate has pencil scratch hardness of greater than or equal to 3h when measured according to an astm d3363 standard at a vertical load of about 0.5 kilograms, and a peak intensity ratio a2/a1 of a peak intensity a2 at a position of about 23.5° in 2θ to a peak intensity a1 at a position of about 15.5° in 2θ of an x-ray diffraction spectrum is greater than or equal to about 0.8.. .
Samsung Sdi Co., Ltd.


 Selectively functionalized porous material patent thumbnailSelectively functionalized porous material
A porous substrate susceptible to one or both of hydroxylation and alkoxylation by a first protic solvent is exposed to a first relative pressure of the first protic solvent. The porous substrate includes a first plurality of pores having a first average pore diameter and a second plurality of pores having a second average pore diameter that is greater than the first average pore diameter.
International Business Machines Corporation


 Test piece analyzing apparatus and test piece analyzing method patent thumbnailTest piece analyzing apparatus and test piece analyzing method
A test piece analyzer and test piece analyzing method which is compact and capable of analyzing a test piece even when mounted obliquely is provided. The test piece analyzer is configured by a test piece holder 11 that includes a mounting part mp for mounting a test piece provided with reagent pads, and an imaging unit 20, wherein the imaging unit 20 is configured to sequentially image the test piece along the longitudinal direction of the mounting part..
Sysmex Corporation


 Antibody-based affinity reagents for binding paclitaxel patent thumbnailAntibody-based affinity reagents for binding paclitaxel
The disclosure is directed to optimized affinity reagent compositions, such as antibodies, antibody fragments, and antibody derivatives, for binding paclitaxel, and related methods of use.. .
Autotelic Llc


Self-shielded, benchtop chemistry system

A self-shielded, bench-top radiochemistry system, including a radioactive isotope dispensing module configured to draw an isotope out of a vial and dispense one or more metered doses of the isotope to a concentration module that concentrates the metered dose into a droplet amount of isotope and a synthesizer module that delivers the droplet amount of isotope along with one or more reagents to an electrowetting on dielectrics (ewod) chip to produce a radiolabeled molecule.. .
Sofie Biosciences, Inc.

Automated driving of an assay

The invention herein relates to conducting assays with an apparatus including a substantially transparent assay cartridge loaded with magnetic beads, and a magnet carrier base positioned below a scanning platform holding the assay cartridge. The assay cartridge includes magnetic beads, sample and control solutions in some wells, and assay reagents in others.
Fannin Innovation Studio, Inc.

Analyte test strip assays, and test strips and kits for use in practicing the same

Methods of evaluating a sample, e.g., a saliva sample, for the presence of an analyte, e.g., glucose, are provided. Aspects of the methods include: placing a sample onto a sample receiving location of a test strip device, where the test strip device includes analyte detection reagents; and then obtaining a signal from the test strip assay device to evaluate the sample for the presence of the analyte; where the methods include contacting the sample with an antibacterial agent at some point during the assay.
Becton, Dickinson And Company

Immunochromatographic test strip and detection method using immunochromatography for detecting object in red blood cell-containing sample

A problem to be solved by the present invention is to provide an immunochromatographic test strip and a detection method using immunochromatography avoiding aggregation of colloidal gold conjugates while red blood cells in whole blood are agglutinated and then separated and removed in the case of using polybrene as a blood-agglutinating agent and the colloidal gold conjugates as a detection reagent. To solve the problem, the present inventers reviewed a past reagent configuration itself from a completely different viewpoint rather than selecting type and amount of polyanions and, as a result of extensive study on each element, the inventers surprisingly found that aggregation of colloidal gold can be suppressed by using a certain buffer solution without using neutralization by polyanions..
Sekisui Medical Co., Ltd.

Lithium reagent composition, and for determing lithium ion amount using same

To provide to a reagent composition used in quantitative measurement of lithium in aqueous solutions such as biological specimens and environmental liquid samples by a simple colorimeter or ultraviolet-visible light spectrophotometer immediately, a reagent composition which permits to measure a concentration of lithium by visual observation, and a method and apparatus for measuring lithium ion by using the reagent. A reagent composition for measuring lithium comprising f28 tetraphenylporphyrin compound as chelating agent, including further a water-soluble organic solvent, a ph modifier and a stabilizer, and a method and apparatus for measuring lithium ion by using the reagent..
Metallogenics Co., Ltd

A fully automated high-precision capillary electrophoresis instrument

A fully automated high-precision capillary electrophoresis instrument, comprising an electrophoresis system, a sample injection flow path, and an automatic sampling flow path; the sampling flow path comprising a shunt waste bottle, which is connected to a four-way connector, a four-way sample injection valve and a buffer syringe pump; the automatic sampling flow path comprises a sampling needle, a sample tray, a cleaning tank, reagent bottles, a buffer tube, a six-channel liquid dispenser, and a syringe pump. The described capillary electrophoresis instrument has a fast sample injection speed, high accuracy, good reproducibility, and can be widely used in automated analysis of different substances by capillary electrophoresis..

Apparatus and methods for parallel processing of microvolume liquid reactions

Disclosed herein are apparatuses and methods for conducting multiple simultaneous micro-volume chemical and biochemical reactions in an array format. In one embodiment, the format comprises an array of microholes in a substrate.
The Board Of Trustees Of The Leland Stanford Junior University

Supercentenarian induced pluripotent stem (scips) cells and methods of making and using thereof

Provided herein are cells and methods for reprogramming ips cells from a supercentanarian and their differentiated derivatives having differences from non-supercentenarian ips derived cells that contribute to disease resistance and longevity. Additionally, provided herein are methods for treatment and prevention of age related diseases by administration of therapeutic scips derived cells or cell derived reagents.
Mandala Biosciences, Llc

Brilliant white cauliflower

The present invention includes cauliflowers with enhanced whiteness and methods for obtaining such cauliflowers. The present invention also provides reagents that can be used in methods for obtaining such cauliflowers..
Seminis Vegetable Seeds, Inc.

Process of manufacturing an electron transport material

In a solvent to produce a first mixture. To the first mixture a reagent is added to produce a second mixture.

Process of manufacturing an electron transport material

A process of dissolving [6,6]-phenyl-c60-butyric-n-2-dimethylaminoethyl ester in a solvent to produce a first mixture. A reagent is added to the first mixture to produce a second mixture.
Phillips 66 Company

Process of manufacturing an electron transport material

In a solvent to produce a first mixture. To the first mixture a reagent is added to produce a second mixture.

Method, apparatus and system for detecting and determining compromised reagent pads by quantifying color changes induced by exposure to a hostile environment

A reagent test paddle includes a contamination detection medium, a reference color bar, at least one chemical test medium, and a unique identifier. The contamination detection medium includes a reagent that changes color in the presence or when exposed to a hostile or inhospitable environment.
Scanadu Incorporated

Methods and reagents for analyzing protein-protein interfaces

The present disclosure provides methods and reagents useful for analyzing protein-protein interfaces such as interfaces between a presenter protein (e.g., a member of the fkbp family, a member of the cyclophilin family, or pin1) and a target protein. In some embodiments, the target and/or presenter proteins are intracellular proteins.
Warp Drive Bio, Inc.

Alpha methylacyl a coenzyme racemase detection

A method of detecting the presence or absence of alpha methylacyl a coenzyme racemase (amacr) is provided. In one embodiment of the method, a fluid including a secretion chosen from at least one of a prostate secretion or a secretion from an accessory glad or a cellular component of the fluid is obtained from a subject.
Wisconsin Alumni Research Foundation

Diagnostic reagents

There is provided a diagnostic reagent useful to determine whether an animal has a tuberculosis infection or has been exposed to a tuberculosis agent, for example a mycobacterium. The reagent is useful to distinguish between such an animal and an animal which has been vaccinated against a tuberculosis infection..
The Secretary Of State For Environment, Food And Rural Affairs Acting Through

Methods and kits for detection of coenzyme q10

The invention provides methods for rapid and quantitative extraction and detection of coenzyme q10 in a sample readily adaptable to high throughput screening methods. The invention further provides reagents and kits for practicing the methods of the invention..
Berg Llc

Specimen processing systems, pipette assemblies and methods for preparing reagents

Systems and methods that enable automated processing of specimens carried on microscope slides are described herein. Aspects of the technology are directed, for example, to automated slide processing apparatuses capable of dispensing liquids onto microscope slides.
Ventana Medical Systems, Inc.

Method for diagnosing colorectal cancer from a human feces sample by quantitive pcr, primers and kit

The present invention relates to the field of detection of colorectal cancer (crc). Specifically it relates to methods for the early detection, risk screening and monitoring of crc and/or adenomatous polyps in a human subject based on the quantification of one or more 16s rdna bacterial sequences in feces.
Universitat De Girona

Sumoylation assay and related reagents

Provided herein and methods and kits for identifying inhibitors of sumoylation. The provided methods include contacting a candidate agent with (i) a sumo-conjugating peptide comprising an n-terminal linker and a detectable tag, and (ii) a sumo comprising a metal complex, under conditions that allow binding between the sumo-conjugating peptide and the sumo, and detecting the detectable tag thereby determining the level of binding between the sumo-conjugating peptide and sumo.
The Uab Research Foundation

Reagent cartridge for detection of cells

An apparatus includes a housing and an actuator. The housing, which defines a reagent volume that can receive a reagent container, can be removably coupled to a reaction chamber.
Geneweave Biosciences, Inc.

Spinal muscular atrophy (sma) treatment via targeting of smn2 splice site inhibitory sequences

The present invention is directed to methods and compositions capable of blocking the inhibitory effect of a newly-identified intronic inhibitory sequence element, named iss-n1 (for “intronic splicing silencer”), located in the smn2 gene. The compositions and methods of the instant invention include oligonucleotide reagents (e.g., oligoribonucleotides) that effectively target the smn2 iss-n1 site in the smn2 pre-mrna, thereby modulating the splicing of smn2 pre-mrna to include exon 7 in the processed transcript.
University Of Massachusetts

Concentrating nucleic acids in urine

Provided is a method for concentrating nucleic acids in urine which can be performed without use of toxic reagents and without centrifugation steps. The method allows a 10× or greater concentration of the nucleic acids, removes impurities, and allows processing of volumes greater than 20 ml as a single sample..
Trovagene, Inc

Mycobacteria pre-analytic reagent

A pre-analytic reagent is provided for liquefaction of a sputum sample and complete inactivation of one or more mycobacteria, e.g., mycobacterium tuberculosis (mtb) suspected of being contained in the sputum sample at room temperature. The pre-analytic reagent may include one or more of each of: a chaotropic agent, a chelator, a reducing agent, a detergent, and acetic acid.
Roche Molecular Systems, Inc.

Control dispensing small precise amounts of liquid reagents

A precision volumetric liquid dispensing instrument is disclosed that includes two pressure sensors and a fluid passageway with a defined volume portion in communication with the two sensors for receiving and distributing liquid in relatively small volumes. One of the pressure sensors is positioned to measure pressure at one portion of the defined volume portion of the fluid passageway and the other of the gas pressure sensors is positioned to measure gas pressure at a different portion of the defined volume portion of the passageway.
Cem Corporation

Integrated microfluidic device for target amplification and microarray detection

In one aspect, the present disclosure provides an integrated microfluidic device for nucleic acid amplification and microarray detection. In one aspect, the device comprises: (1) a microchip configured to process reagents, comprising a plurality of reservoirs, channels, valves, and/or fluid interfaces; (2) an amplification chamber for pcr, carried out in a detachable tube assembled on the microchip through a joint; and (3) a microarray chamber comprising a microarray and a reaction chamber.
Tsinghua University

Control dispensing small precise amounts of liquid reagents

A precision volumetric liquid dispensing instrument is disclosed that includes two pressure sensors and a fluid passageway with a defined volume portion in communication with the two sensors for receiving and distributing liquid in relatively small volumes. One of the pressure sensors is positioned to measure pressure at one portion of the defined volume portion of the fluid passageway and the other of the gas pressure sensors is positioned to measure gas pressure at a different portion of the defined volume portion of the passageway.
Cem Corporation

Analyte detection devices and methods with hematocrit/volume correction and feedback control

Disclosed are devices, arrangements and methods for quantifying the concentration of an analyte present in bodily fluid, including: an assay pad having at least one chemical reagent capable of producing a detectable signal in the form of a reaction spot upon reaction with the analyte; a light source; a detector array; a processor; and a memory in communication with the processor, the memory comprising: (a) at least one value indicative of one or more of: (i) the level of hematocrit contained in the sample; (ii) the volume of the sample applied to the assay pad; or (iii) imperfections present in the reaction spot; and (b) at least one algorithm for calculating the concentration of the analyte contained in the sample.. .
Intuity Medical, Inc.

Method of generating electron transfer dissociation reagent ions

A method of mass spectrometry is disclosed wherein ions are subjected to an electron detachment, electron capture or electron transfer process in order to form ions having a different charge state. At least some of the ions having a different charge state are caused to interact with analyte ions to cause at least some of the analyte ions to fragment to form daughter, fragment or product ions..
Micromass Uk Limited

Automated reagent dispensing system and operation

A system and method that enables automated reagent dispensing for tissue stainers. The stainers receive staining protocols from a central controller.
Sakura Finetek U.s.a., Inc.

Antibodies to ttr and methods of use

The disclosure pertains to antibodies and binding fragments thereof that specifically binds all or part of ehaevvfta. Also provided are isolated peptides, isolated nucleic acids, immunogens, compositions, immunoassays and kits and method of using said reagents to detect misfolded ttr..
University Health Network

Method for detection of basic peptide and reagent for detection of basic peptide

The present invention provides a method for detection of a basic peptide by mixing a sample suspected to contain the basic peptide and a reagent containing denatured albumin and detecting turbidness due to a complex of the basic peptide and denatured albumin.. .
Kagoshima University

Endocrine disruptor field tester

The iontox endocrine field tester (eft) provides an easy method for determining the presence, type, and amount of endocrine active chemicals. By developing a bead/receptor/column/reagent for only the target hormones, it is possible to detect a broad range of endocrine active materials for each receptor type.
Iontox, Llc

Methods and compositions for assaying blood levels of legumain

In one aspect, a homogenous assay method for determination of blood levels of legumain molecules (an asparaginyl endopeptidase) is disclosed. In one aspect, the assay utilizes specific sizes of nanoparticles that are coated with antibody or antibodies specifically towards legumain molecule or its fragment(s).

Methods and compositions for assaying blood levels of legumain

In one aspect, a homogenous assay method for determination of blood levels of legumain molecules (an asparaginyl endopeptidase) is disclosed. In one aspect, the assay utilizes specific sizes of nanoparticles that are coated with antibody or antibodies specifically towards legumain molecule or its fragment(s).

Exhaust line with a reagent injector

The exhaust line comprises an injection segment including at least one cup having a large upstream face directly sprayed with the exhaust gases and dividing a circulation passage into an upstream space and a downstream space. The injection segment comprises at least one circumferential conduit fluidically connecting the upstream space to the downstream space.
Faurecia Systemes D 'echappement

Custom ionic liquid electrolytes for electrolytic decarboxylation

Methods, equipment, and reagents for preparing organic compounds using custom electrolytes based on different ionic liquids in electrolytic decarboxylation reactions are disclosed.. .
Ceramatec, Inc

Formalin fixed paraffin embedded (ffpe) control reagents

The disclosure provides a plurality of nucleic acid sequences comprising multiple variants of a reference sequence. The disclosure further provides plasmids, cells, methods and kits comprising the same..
Microgenics Corporation

Genome editing without nucleases

Methods and compositions are provided for editing the genome of a cell without the use of an exogenously supplied nuclease. Aspects of the methods include contacting a cell with a targeting vector comprising nucleic acid sequence to be integrated into the target locus, where the cell is not also contacted with a nuclease.
The Board Of Trustees Of The Leland Stanford Junior University

Polyurethane adhesive layers for electro-optic assemblies

Electro-optic assemblies and related materials (e.g., adhesive) for use therein are generally provided. The adhesive layer may comprise an end-capped polyurethane.
E Ink Corporation

Il-22 polypeptides and il-22 fc fusion proteins and methods of use

The invention relates to il-22 polypeptides, il-22 fc fusion proteins and il-22 agonists, composition comprising the same, methods of making and methods of using the composition for the treatment of diseases. The invention also relates to il-22 receptor associated reagents and methods of use thereof..
Genentech, Inc.

Stabilized compounds having secondary structure motifs

The present invention provides novel stabilized crosslinked compounds having secondary structure motifs, libraries of these novel compounds, and methods for the synthesis of these compounds libraries thereof. The synthesis of these novel stabilized compounds involves (1) synthesizing a peptide from a selected number of natural or non-natural amino acids, wherein said peptide comprises at least two moieties capable of undergoing reaction to promote carbon-carbon bond formation; and (2) contacting said peptide with a reagent to generate at least one crosslinker and to effect stabilization of a secondary structure motif.
President And Fellows Of Harvard College

Method for monofluoromethylation of organic substrates to prepare biologically active organic compounds

Described is a process for the preparation of monofluoromethylated organic biologically active compounds using monofluoromethylated reagents. Fluticasone propionate and fluticasone furoate can be prepared using, for example, s-monofluoromethyl-s-phenyl-2,3,4,5-tetramethylphenylsulfonium tetrafluoroborate as monofluoromethylating reagent instead of bromofluoromethane..
Hovione Inter Limited

Method of producing 2'-trifluoromethyl group-substituted aromatic ketone

A method produces a 2′-trifluoromethyl-substituted aromatic ketone and includes reacting a 2-halogen-substituted benzotrifluoride compound with magnesium metal to convert the compound to a grignard reagent; and reacting the grignard reagent with an acid anhydride; and then hydrolyzing the resultant to produce a 2′-trifluoromethyl-substituted aromatic ketone. The method of producing a 2′-trifluoromethyl-substituted aromatic ketone enables 2′-trifluoromethyl-substituted aromatic ketone to be produced without using expensive raw materials by generating a grignard reagent as an intermediate and reacting this grignard reagent with an acid anhydride in an efficient productivity.
Toray Fine Chemicals Co., Ltd.

Urea sulfate and sodium chloride blend for regeneration of cation exchange resins

Methods and systems for acid regeneration of ion exchange resins are disclosed. Acid resins designed for use in a variety of cleaning application using a water source use a treated, softened, acidic water source according to the invention.
Ecolab Usa Inc.





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This listing is a sample listing of patent applications related to Reagent for is only meant as a recent sample of applications filed, not a comprehensive history. There may be associated servicemarks and trademarks related to these patents. Please check with patent attorney if you need further assistance or plan to use for business purposes. This patent data is also published to the public by the USPTO and available for free on their website. Note that there may be alternative spellings for Reagent with additional patents listed. Browse our RSS directory or Search for other possible listings.


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