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Reagent

Reagent-related patent applications - as published by the U.S. Patent and Trademark Office (USPTO).


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Methods for mass spectrometry of mixtures of protein or polypeptides using proton transfer reaction
Thermo Finnigan Llc
April 12, 2018 - N°20180102243

A method comprises: (1) making an extract of a biological sample; (2) repeatedly: (a) choosing a respective one of a plurality of pre-determined protein or polypeptide analyte compounds; (b) introducing a portion of the extract into an electrospray ionization source, thereby generating positive ions comprising a plurality of ion species; (c) isolating a plurality of subsets of the ion species comprising respective ...
Reagents and methods for simultaneously detecting absolute concentrations of a plurality of elements in a ...
New York University
April 12, 2018 - N°20180102240

Disclosed herein are internal standard compositions, a plurality of calibration standards, and one or more kits for use with mass spectrometry, particularly for use with an inductively coupled plasma mass spectrometer capable of simultaneous detection of a large number of ionization products over a large range of masses. Methods of using these reagent materials for the simultaneously detection of absolute ...
Automated analyzer
Hitachi High-technologies Coproration
April 12, 2018 - N°20180100871

A control section causes one dispensing mechanism of either a reagent dispensing mechanism or a sample dispensing mechanism to first discharge a predetermined amount of a liquid into the reaction container, and then, with respect to the cases where the amount of a liquid to be discharged by the other dispensing mechanism is larger or smaller than the amount of ...
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Solar device for autonomous refrigeration by solid-gas sorption
Centre National De La Recherche Scientifique
April 12, 2018 - N°20180100676

A device is provided for the autonomous production of refrigeration approximately 40° c. Lower than ambient temperature from a low-temperature solar thermal source, the device including: (i) a reactor arranged to cool and/or heat the solid reagent; (ii) a condenser; (iii) a first tank for storing the liquid refrigerant at ambient temperature; (iv) an enclosure arranged to store a ...
Instrument for cassette for sample preparation
Luminex Corporation
April 12, 2018 - N°20180100186

A parallel processing system for processing samples is described. In one embodiment, the parallel processing system includes an instrument interface parallel controller to control a tray motor driving system, a close-loop heater control and detection system, a magnetic particle transfer system, a reagent release system, a reagent pre-mix pumping system and a wash buffer pumping system.
Isotachophoresis enhanced isothermal nucleic acid amplification
University Of Washington
April 12, 2018 - N°20180100183

The present disclosure relates generally to the integration of isotachophoresis (itp) and isothermal nucleic acid amplification methods such as recombinase polymerase amplification (rpa). One aspect of the disclosure relates to a method for concentrating and amplifying a nucleic acid, the method including an isotachophoresis device, the isotachophoresis device including a porous matrix, and first and second electrodes, having a leading ...
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Enhanced processes and reagents for host engineering
Invista North America S.a.r.l.
April 12, 2018 - N°20180100160

Nonnaturally occurring host cells altered to increase their ability to transfer genetic molecules into the host cells as compared to an unaltered host cell are provided. Also provided are methods for identifying endogenous loci of a host cell which inhibit transformation efficiency and/or electroporation of genetic molecules into the cell as well as methods for producing nonnaturally occurring host ...
Self-contained anaerobic environment-generating culture device
3m Innovative Properties Company
April 12, 2018 - N°20180100131

A device for culturing anaerobic microorganisms is provided. The device comprises a body comprising a waterproof base, a waterproof coversheet attached to the base, and a growth compartment disposed between the base and the coversheet. The growth compartment has a perimeter and an opening that provides liquid access to the growth compartment. A portion of the perimeter is defined by ...
Method capable of being used for protein renaturation independently or being used as preceding operations ...
April 12, 2018 - N°20180099992

Provided is a method of treating a protein to be renatured, including: (1) mixing the protein to be renatured with a denaturing solution containing a denaturing reagent; (2) incubating a resulting mixture at such a low temperature that the denaturing agent is gradually precipitated from the denaturing solution, resulting in a decreasing concentration gradient of the denaturing agent and an increasing concentration ...
Process for selectivating catalyst for producing paraxylene by methylation of benzene and/or toluene
Exxonmobil Chemical Patents Inc.
April 12, 2018 - N°20180099915

A process is described for producing paraxylene, in which an aromatic hydrocarbon feedstock comprising benzene and/or toluene is contacted with an alkylating reagent comprising methanol and/or dimethyl ether in an alkylation reaction zone under alkylation conditions in the presence of an alkylation catalyst to produce an alkylated aromatic product comprising xylenes. The alkylation catalyst comprises a molecular sieve ...
Process for producing paraxylene by methylation of benzene and/or toluene
Exxonmobil Chemical Patents Inc.
April 12, 2018 - N°20180099913

A process is described for producing paraxylene, in which an aromatic hydrocarbon feedstock comprising benzene and/or toluene is contacted with an alkylating reagent comprising methanol and/or dimethyl ether in an alkylation reaction zone under alkylation conditions in the presence of an alkylation catalyst to produce an alkylated aromatic product comprising xylenes. The alkylation catalyst comprises a molecular sieve ...
Cartridge for testing a sample
Boehringer Ingelheim Vetmedica Gmbh
April 12, 2018 - N°20180099277

A cartridge for testing a biological sample. The cartridge has a closure element that is fastened to the cartridge in a form-fit or interlocking manner and is a multi-component injection molded closure part having an integrated seal so as to be able to fluidically close a receiving cavity having an integrated vent. The cartridge also has a film cover and ...
Reagent storage in microfluidic systems and related articles and methods
Opko Diagnostics, Llc
April 12, 2018 - N°20180099272

Fluidic devices and methods including those that provide storage and/or facilitate fluid handling of reagents are provided. Fluidic devices described herein may include channel segments positioned on two sides of an article, optionally connected by an intervening channel passing through the article. The channel segments may be used to store reagents in the device prior to first use by ...
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Mesoporous silica nanoparticles with lipid bilayer coating for cargo delivery
The Regents Of The University Of California
April 12, 2018 - N°20180098945

A nanocarrier including a silica body having a surface and defining a plurality of pores that are suitable to receive molecules therein is described. The nanocarrier also includes a lipid bilayer coating the surface, and a cargo-trapping agent within the phospholipid bilayer. The phospholipid bilayer stably seals the plurality of pores. The cargo-trapping reagent can be selected to interact with ...
Acrylic hair fixative copolymers and compositions
Akzo Nobel Chemicals International B.v.
April 12, 2018 - N°20180098930

A hair fixative composition comprising a film forming polymer that is prepared from monomers comprising (a) 10-30% by weight of one or more copolymerizable comonomers selected from the group consisting of n-alkyl (meth)acrylamide wherein the alkyl group thereof contains from 2 to 12 carbon atoms, wherein for at least one of said copolymerizable comonomers the alkyl group contains from 5 to 12 carbon ...
Standard cell suspension
Hitachi Chemical Company, Ltd.
April 05, 2018 - N°20180095086

The present invention relates to a standard cell suspension for confirming the stainability of a treatment solution that differentially stains circulating tumor cells (ctcs) and leucocytes, containing (a) a cell line having an antigen that is specific for human cancer cells and (b) a cell line having an antigen that is specific for human leukocytes, wherein the (a) and (b) ...
Thermochemical-based antibody inactivation methods and systems
Ventana Medical Systems, Inc.
April 05, 2018 - N°20180095082

Methods, systems, compositions, and thermochemical processes for inactivating proteinaceous binding entities (pbes) such as antibodies in between staining cycles for preventing cross-reactivity in subsequent staining cycles. The thermochemical methods, compositions, or systems may feature incubating a sample in a solution comprising a buffer at a temperature sufficient to reduce or eliminate further detectability of the pbe. The methods, compositions, and ...
Method of multiplex immunoassays utilizing differential affinity and methods for synthesizing aptamer-based reagents for multiplex ...
April 05, 2018 - N°20180095078

Multiplex immunoassays utilize the differential affinities among the conjugation pairs between the capture ligands and target analytes are proposed. Window magnetic-assisted rapid aptamer selection (window-maras) methods for selecting aptamers with desirable affinity toward the target analytes and methods for generating reagents for multiplex immunoassays or multiplex detection in one assay by utilizing the selected aptamers as capture ligands in reagents ...
Devices and methods for sample analysis
Abbott Laboratories
April 05, 2018 - N°20180095067

Integrated microfluidic and analyte detection devices are disclosed, along with methods of detecting target analytes. Digital microfluidic and analyte detection devices include a first substrate and a second substrate aligned generally parallel to each other to define a gap therebetween, the first substrate including a plurality of electrodes to generate electrical actuation forces on a liquid droplet disposed in the ...
Biosensor
April 05, 2018 - N°20180095052

Disclosed herein is a biosensor. The biosensor includes: a mount; a bio-sensing chip disposed on the mount and including at least one thin film transistor; a reaction layer disposed on the bio-sensing chip and including at least one of a biological sample and a biochemical reaction reagent; an upper electrode disposed on an upper surface of the reaction layer and ...
Biosensor, production method thereof, and method and system for measuring glucose or lactate
Arkray, Inc.
April 05, 2018 - N°20180095048

Disclosed is a biosensor with improved humidity resistance that can be used as a glucose sensor or a lactate sensor. The biosensor includes: an insulative substrate; an electrode system having a working electrode and a counter electrode provided on the substrate; and a reagent layer provided on the electrode system. The reagent layer contains an oxidoreductase and 1-methoxy-5-methylphenazinium ethyl ...
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