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Reagent

Reagent-related patent applications - as published by the U.S. Patent and Trademark Office (USPTO).


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Processing reagent and use thereof in assays for detection of analytes associated with a binding ...
Quidel Corporation
October 12, 2017 - N°20170292964

Methods for preparing a sample for detection of an analyte of interest that is bound in vivo to a protein are provided. The method comprises providing a processing reagent comprising metaperiodate and contacting a sample suspected of comprising an analyte of interest associated with a protein with the processing reagent to form a mixture. The analyte of interest, if present ...
Methods for proteomic profiling using non-natural amino acids
California Institute Of Technology
October 12, 2017 - N°20170292958

The invention provides methods, reagents and systems for incorporating non-natural amino acids into proteins, preferably in vivo, using the endogenous protein synthesis machinery of an organism. The incorporated non-natural amino acids contain reactive groups for further chemical reagents, which may serve as a “handle” to enrich the proteins or fragments thereof in a number of uses, ...
Electrophoretic matrix staining composition and method
Pierce Biotechnology, Inc.
October 12, 2017 - N°20170292932

Staining compositions and methods for use with a matrix, such as an electrophoretic gel, containing separated biopolymers. The compositions including an acid, an organic solvent, and a generally planar, fluid-permeable gel contact sheet consisting primarily of a non-cellulosic material. The acid and organic solvent may be sorbed to the fluid-permeable gel contact sheet, or may be sorbed to a layers ...
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Methods, compositions, and kits comprising linker probes for quantifying polynucleotides
Applied Biosystems, Llc
October 12, 2017 - N°20170292158

The present invention is directed to methods, reagents, kits, and compositions for identifying and quantifying target polynucleotide sequences. A linker probe comprising a 3′ target specific portion, a loop, and a stem is hybridized to a target polynucleotide and extended to form a reaction product that includes a reverse primer portion and the stem nucleotides. A detector probe, a specific ...
Method for breaking nucleic acid and adding adaptor by means of transposase, and reagent
Bgi Shenzhen Co., Limited
October 12, 2017 - N°20170292153

Provided are a method for breaking a nucleic acid and adding an adaptor by means of a transposase, and a reagent. The method comprises the following steps: conducting random breaking of a nucleic acid by using a transposase-embedded complex, wherein the transposase-embedded complex comprises a transposase and a first adaptor comprising a transposase identification sequence, and two ends of the ...
Systems and methods for sampling of amplification products
Caliper Life Sciences, Inc.
October 12, 2017 - N°20170292152

The invention provides systems and methods for processing samples. In a method, a reaction card is provided that has a channel network, a valve, and a micropump, all disposed within the card. The reaction card also has a collection well disposed on a surface of the card and a tubular member extending out from the card. A reaction vessel is ...
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Reagent Patent Applications
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  • 865+ full patent PDF documents of Reagent-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
Diagnostic method for determining the presence and amount of human interleukin-3 in a sample using ...
Universitatsklinikum Regensburg
October 12, 2017 - N°20170291941

For determining the presence and amount of human interleukin 3 (il-3) in a sample, the present invention provides a diagnostic method, wherein an anti-il-3-antibody, fragment or construct thereof is added to said sample under conditions which allow for binding said antibody, fragment or construct thereof to il-3 and detecting the amount of antibody bound il-3 in said sample, wherein the ...
Process for the preparation of toltrazuril and an intermediate useful for its preparation
Universitatsklinikum Regensburg
October 12, 2017 - N°20170291880

Wherein intermediate (iii) is obtained via a novel intermediate without the use of potentially hazardous reagents or potentially unstable intermediates.
Polyfluoroalkyl allyl compound and method for producing the same
Universitatsklinikum Regensburg
October 12, 2017 - N°20170291865

(n, a, and b are as defined above, and r′: a c1-c3 alkyl group) with a transition metal. This method for producing provides a polyfluoroalkyl allyl compound used as a synthetic intermediate for a fluorine-containing alkylsilane compound that can remove free iodine derived from the raw material compound, before a hydrosilylation reaction is performed, without using a metal ...
Method for converting lime-based wet flue gas desulfurization systems to limestone-based systems
Aecom Technical Services, Inc.
October 12, 2017 - N°20170291137

A flue gas desulfurization unit is converted from operating with lime or magnesium enhanced lime under inhibited oxidation into a unit that operates using limestone under inhibited oxidation conditions. A ball mill grinding unit may be installed to crush the limestone thereby producing a suspended slurry of fine limestone particles which is pumped to the reaction vessel. When installed, the ...
Conjugates and conjugating reagents
Aecom Technical Services, Inc.
October 12, 2017 - N°20170290925

In which pr represents said protein or peptide, each nu represents a nucleophile present in or attached to the protein or peptide, each of a and b independently represents a c1-4alkylene or alkenylene chain, and w′ represents an electron withdrawing group or a group obtained by reduction of an electron withdrawing group; and in which said polyethylene ...
Reagent for prothrombin time measurement, method for production thereof, and method for measurement of prothrombin ...
Sysmex Corporation
October 05, 2017 - N°20170285046

Disclosed is a reagent for prothrombin time measurement, wherein the reagent contains a liposome composition containing a first liposome having a phospholipid layer, a second liposome having a phospholipid layer of a different composition from that of the first liposome, and tissue factor, wherein the tissue factor is associated with the phospholipid layer of at least one of the first ...
System for chemiluminescence-based detection of methicillin-resistant staphylococcus aureus
Nanodetection Technology, Inc.
October 05, 2017 - N°20170285026

The present disclosure comprises a device and accompanying method for determining the presence or absence of methicillin-resistant staphylococcus aureus in a sample. The disclosure includes the following elements: (1) a lateral flow strip for microfluidic manipulation of a sample; (2) a cassette device for containing the lateral flow strip and enabling interface with a detection device; (3) a cassette handler; (4) a luminous reagent ...
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Reagent Patent Applications
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  • 865+ full patent PDF documents of Reagent-related inventions.
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Reagents and methods for detecting pnh type ii white blood cells and their identification as ...
Alexion Pharmaceuticals, Inc.
October 05, 2017 - N°20170285013

The disclosure relates to methods for detecting pnh type ii cell populations in biological samples as well as methods for determining whether a patient is at an increased risk for developing thrombocytopenia or thrombosis based on the percentage of pnh type ii cells in the patient's blood. The disclosure also features reagents and conjugates for use in the methods.
Systems and methods for electrochemical creatinine assays
Polymer Technology Systems, Inc.
October 05, 2017 - N°20170284954

A system for the electrochemical detection of creatinine levels includes a test strip including an electrode and a counter electrode, the electrode and counter electrode located proximate to a sample reception area; and a coating on one of the electrode and counter electrode, the coating including a reagent coating for creatinine.
Methods for diagnosis, prognosis and monitoring of breast cancer and reagents therefor
Garvan Institute Of Medical Research
October 05, 2017 - N°20170283886

The present disclosure provides methods and reagents for the diagnosis, prognosis or the monitoring of breast cancer, including various subtypes of breast cancer including, for example, estrogen receptor (er) negative breast cancer, er positive breast cancer, triple negative breast cancer (tnbc) and other subtypes of breast cancer.
Method and reagents for detecting water contamination
Dow Global Technologies Llc
October 05, 2017 - N°20170283861

A method of examining a water supply for microbial contamination involves contacting a water supply with a novel reagent having high specificity for a legionella microbial species, wherein said reagent does not cross-react, or minimally cross-reacts, with a microbial species other than legionella. The method further involves detecting, or measuring, a contaminating concentration of a legionella species in the water ...
Microfluidic siphoning array for nucleic acid quantification
Combinati, Inc.
October 05, 2017 - N°20170283855

A microfluidic device can have a plurality of microchambers connected to a microchannel via siphon apertures. The microfluidic device may be formed from a thermoplastic and capped by a thermoplastic thin film. The microfluidic device may be used for digital polymerase chain reactions by forcing reagent into the microchambers at low pressure via an inlet, forcing any gas trapped in ...
Reagent for prothrombin time measurement, method for production thereof, and method for measurement of prothrombin ...
Sysmex Corporation
October 05, 2017 - N°20170283853

Disclosed is a reagent for prothrombin time measurement, containing a tissue factor and a surfactant, wherein the value of formula (i), which is represented by (surfactant amount (μmol))/(total protein amount (μg)), is 0. 013 to 0. 05 μmol/μg.
Rna interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (sina)
Sirna Therapeutics, Inc.
October 05, 2017 - N°20170283816

The present invention concerns methods and reagents useful in modulating gene expression in a variety of applications, including use in therapeutic, diagnostic, target validation, and genomic discovery applications. Specifically, the invention relates to synthetic chemically modified small nucleic acid molecules, such as short interfering nucleic acid (sina), short interfering rna (sirna), double-stranded rna (dsrna), micro-rna (mirna), and short hairpin rna (...
Compositions and methods relating to synthetic rna polynucleotides created from synthetic dna oligonucleotides
New England Biolabs, Inc.
October 05, 2017 - N°20170283797

Compositions and methods are provided for forming a single rna polynucleotide from a plurality of dna oligonucleotides in a single reaction chamber using combined reagents in a single step reaction. Dna polymerase, rna polymerase and single stranded (ss) dna oligonucleotides are combined where each dna oligonucleotide has one or more sequence modules, wherein one sequence module in the first ss ...
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