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Reagent

Reagent-related patent applications - as published by the U.S. Patent and Trademark Office (USPTO).


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NEW Pancreatic cancer biomarkers and uses thereof
Somalogic, Inc.
February 15, 2018 - N°20180045739

The present disclosure includes biomarkers, methods, devices, reagents, systems, and kits for the detection and diagnosis of cancer generally and pancreatic cancer specifically. In one aspect, the disclosure provides biomarkers that can be used alone or in various combinations to diagnose cancer generally or pancreatic cancer specifically. In another aspect, methods are provided for diagnosing pancreatic cancer in an individual, ...
NEW Chemically functionalized array to analyze protein modifications
Tymora Analytical Operations Llc
February 15, 2018 - N°20180045734

Methods and chemicals for the capture and analysis of a selected group of protein modifications. Post-translational modifications alter the functional groups in proteins. The resulting modified proteome is useful for biomarker discovery, clinical diagnostics, and protein dynamics. Present immunoassays to quantify modified proteins are limited by their dependence on antibodies, which are often not specific for post-translational modifications. This invention ...
NEW Molecular profiling for cancer
Caris Mpi, Inc.
February 15, 2018 - N°20180045727

Provided herein are methods and systems of molecular profiling of diseases, such as cancer. In some embodiments, the molecular profiling can be used to identify treatments for the disease, such as treatments that provide likely benefit or likely lack of benefit for the disease. The molecular profiling can include analysis of a sequence of a nucleic acid. The invention provides ...
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NEW Dual chamber reagent mixing container
Instrumentation Laboratory Company
February 15, 2018 - N°20180045627

Described is an automated reagent mixing container for separately storing and automatically mixing together at least two stored reagent components.
NEW Methods and reagents for detecting ebola virus
The United States Of America, As Represented By The Secretary, Department Of Health And Human Serv
February 15, 2018 - N°20180044741

Probes and primers are disclosed for detecting ebov nucleic acid in a sample. Methods are also disclosed that utilize these probes and primers, wherein the methods can be used to detect an ebov in a sample to identify a subject with an ebov infection.
NEW Method and system for sequencing nucleic acids
Omniome, Inc.
February 15, 2018 - N°20180044727

Provided are compositions, methods and systems for determining the sequence of a template nucleic acid using a polymerase-based, sequencing-by-binding procedure. An examination step involves monitoring the interaction between a polymerase and template nucleic acid in the presence of one or more nucleotides. Identity of the next correct nucleotide in the sequence is determined without incorporation of any nucleotide into the ...
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NEW Tissue processing apparatus and method for infusing bioactive agents into tissue
Warsaw Orthopedic, Inc.
February 15, 2018 - N°20180044638

A tissue treatment apparatus and method for treating bone tissue has a controller, an enclosure, a reagent supply system, a draining configuration, and a gas relief valve is controlled by the controller. A bioactive agent may be applied through the reagent supply system. Optionally provided is a gas evacuation assembly, a gas supply unit, a thermal unit for heating or ...
NEW Reagent component dispensing caps for reagent containers used in automated clinical analyzers
Instrumentation Laboratory Company
February 15, 2018 - N°20180043363

Described is an automated reagent dispensing cap and methods of use in an automated clinical analyzer for introducing one or more reagent components housed in the reagent dispensing cap into a container enclosing another reagent component with which it is combined to achieve a reagent useful for diagnostic testing.
NEW Pipette components useful for medical diagnostics
Siemens Healthcare Diagnostics Inc.
February 15, 2018 - N°20180043348

A pipette is described having a tube, a pressure mechanism, and at least one reagent pad. The tube has a first end, a second end opposite the first end, and a sidewall extending between the first end and the second end, with the sidewall defining an interior cavity. The pressure mechanism is operably connected to the first end of the ...
NEW Catalytic composition and process for the dehydrogenation of butenes or mixtures of butanes and butenes ...
Versalis S.p.a.
February 15, 2018 - N°20180043338

The present invention relates to a dehydrogenation process starting from reagents selected from single butenes, or mixtures thereof, or mixtures of butenes with butanes, to give 1-3 butadiene using catalytic composition of microspheroidal alumina and an active component containing a mixture comprising gallium and/or gallium oxides, tin and/or tin oxides, a quantity ranging from 1 ppm to 500 ppm with ...
NEW Degradable thiol-ene polymers and methods of making thereof
Mosaic Biosciences, Inc.
February 15, 2018 - N°20180043030

Provided are methods for linking polypeptides (including peptides and proteins) to other moieties using radical imitated thiol-ene chemistries, for example, modifying a polypeptide by introducing reactive thiol groups and reacting the thiol groups with olefin-containing reagents or alkyne-containing reagents under conditions that support radical thiol-ene or thiol-yne reactions. The reactive thiol groups have greater activity for radical thiol-ene reactions that ...
NEW Reagents and methods for identifying, enriching, and/or expanding antigen-specific t cells
The Johns Hopkins University
February 15, 2018 - N°20180043003

Antigen-specific t cells, including nave t cells, and including rare precursor cells are enriched and expanded in culture. Enrichment and expansion provides a platform for more effective immunotherapy by adoptive transfer, as well as platforms for personalizing immunotherapy by determining t cell reactivity with a library of candidate peptide antigens.
NEW Reagents and methods for inhibiting or disrupting biofilm
Institute Of Microbiology, Chinese Academy Of Sciences
February 15, 2018 - N°20180042243

The present disclosure provides an inhibitor for inhibiting or disrupting biofilm and use thereof. Specifically, the present disclosure an application of a psig protein and a coding sequence thereof in inhibiting or disrupting a biofilm of a microorganism. The present disclosure also provides a composition and a preparation containing the psig protein to inhibit or disrupt a biofilm of a ...
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Reagent Patent Applications
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  • 865+ full patent PDF documents of Reagent-related inventions.
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Method for producing electrotechnical thin layers at room temperature, and electrotechnical thin layer
Dynamic Solar Systems Ag
February 08, 2018 - N°20180040429

The present method for the first time proposes a method for producing an electrotechnical thin layer which makes it possible to carry out process control at room temperature by using an additional reagent, thereby providing stable, thin layers in a very short time. Capacitive accumulators that could replace a li-ion battery in a tablet pc and more far-reaching applications are ...
Method of lipid assay and reagent for use therein
Sekisui Medical Co., Ltd.
February 08, 2018 - N°20180038878

A method of lipid assay characterized by assaying the lipids contained in a blood component in the presence of an organic silicon compound. The method can cause specific conditions for direct methods while satisfying requirements such as no influence on precision of assay, no burden on assay apparatus, and easy availability.
Method of detecting an endotoxin using limulus amebocyte lysate substantially free of coagulogen
Lonza Walkersville, Inc.
February 08, 2018 - N°20180038864

The present invention is related to a method of detecting an endotoxin in a sample using a chromogenic assay, the method comprising: (a) contacting the sample with a reagent comprising limulus amebocyte lysate (lal) and a chromogenic substrate; and (b) measuring a chromogenic effect resulting from a change in the chromogenic substrate in the presence of endotoxin in the sample; ...
Treating mental disorders
Tla Targeted Immunotherapies Ab
February 08, 2018 - N°20180038861

A method for treating mental disorders such as schizophrenia, depression and bipolar disorder comprises applying peripheral blood from a patient or subject to an apheresis column loaded with a solid support comprising a binding reagent capable of specifically binding to a chemokine receptor, optionally the chemokine receptor ccr9, ccr1, ccr3 and/or ccr5 immobilized directly or indirectly on the support ...
Treating cancer
Tla Targeted Immunotherapies Ab
February 08, 2018 - N°20180038860

A method for treating cancer comprising applying peripheral blood from a patient or subject to an apheresis column loaded with a solid support comprising one or more binding reagents capable of specifically binding to a chemokine receptor, optionally the chemokine receptor ccr7, ccr5, ccr6, ccr8, cxcr4, cxcr7, ccr4, ccr9, ccr10, cxcr3 or cxcr5 or to a treg receptor immobilized directly ...
Treating conditions associated with sepsis
Tla Targeted Immunotherapies Ab
February 08, 2018 - N°20180038859

A method for treating sepsis and/or respiratory distress syndrome (rds) comprises applying peripheral blood from a patient or subject to an apheresis column loaded with a solid support comprising one or more binding reagents capable of specifically binding to a chemokine receptor, optionally the chemokine receptor ccr5, cxcr1, cxcr2, and/or ccr2 immobilized directly or indirectly on the support ...
Treating respiratory conditions
Tla Targeted Immunotherapies Ab
February 08, 2018 - N°20180038858

A method for treating a respiratory conditions comprises applying peripheral blood from a patient or subject to an apheresis column loaded with a solid support comprising one or more binding reagents capable of specifically binding to a chemokine receptor, optionally the chemokine receptor ccr2, ccr1, ccr3, ccr5, cxcr1, cxcr2 and/or ccr7 immobilized directly or indirectly on the support thus ...
Treating multiple sclerosis
Tla Targeted Immunotherapies Ab
February 08, 2018 - N°20180038857

A method for treating multiple sclerosis comprises applying peripheral blood from a patient or subject to an apheresis column loaded with a solid support comprising one or more binding reagents capable of specifically binding to a chemokine receptor, optionally the chemokine receptor ccr2, ccr6, ccr3, ccr5, ccr1, cxcr3 and/or ccr9 immobilized directly or indirectly on the support thus removing ...
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