This page is updated frequently with new Reagent-related patent applications.
|Method of doping an organic semiconuctor and doping composition|
A method of forming a n-doped semiconductor layer wherein a film comprising an organic semiconductor and an n-dopant reagent is irradiated by light having a wavelength that is within an absorption range of the organic semiconductor, and wherein an absorption maximum wavelength of the n-dopant precursor is shorter than any peak wavelength of the light. The n-doped semiconductor layer may be an electron-injection layer of an organic light-emitting device..
Sumitomo Chemical Company Limited
|Method and destructing compromised devices|
The system and method for destroying compromised objects, including electronic devices. The system and method utilizes a barrier separating two reagents that can be rapidly mixed to form a base when desired.
Bae Systems Information And Electronic Systems Integration Inc.
|Blood state analysis device, blood state analysis system, blood state analysis method, and storage device|
A blood state analysis device (1) that analyzes a state of a blood sample, as used for clotting time testing, said blood sample comprising a plasma and at least one reagent, including a correction unit (11) configured to correct a measured blood coagulation evaluation result of the blood sample based on a relation between reference concentrations of the at least one reagent in plasma and reference blood coagulation evaluation results, the at least one reagent is an anticoagulation treatment releasing agent, a coagulation activator, an anticoagulant, a platelet activator, an antiplatelet drug, or a combination thereof and is present in the blood sample. For instance, such device (1) allows to correct blood clotting time results with respect to concentrations of an anti-coagulant drug present in the blood sample..
|Method for measuring clotting time, measurement device for clotting time, and reagent kit|
Wherein the blood sample is mixed with the manganese ion-forming compound separately from the activator and the phospholipid in the mixing step.. .
|Biomarkers of osteoarthritis|
Biomarkers, biomarker panels and methods for diagnosing osteoarthritis (oa) and determining treatment are disclosed, using measurement of the expression level of certain polypeptides in a test sample from a subject, including mcp1, il8, kc, mmp2, mmp3, apolipoprotein a1, and apolipoprotein e. Related methods for monitoring oa treatment efficacy, diagnostic reagents, and kits are also described..
The Curators Of The University Of Missouri
|Method for detecting analyte, detection reagent kit, and detection reagent|
Wherein the second trapping body comprises a binding substance which binds to the analyte, a support, and a linker which links the binding substance and the support with each other.. .
|Magnesium sensing membrane for potentiometric ion selective electrode for measuring ionized magnesium and methods of production and use thereof|
A magnesium sensing membrane is disclosed for use in a potentiometric ion selective electrode that exhibits improved stability upon exposure to surfactant-containing reagents. Kits containing same are disclosed, along with methods of production and use of the magnesium sensing membrane..
Siemens Healthcare Diagnostics Inc.
|Sample collection and bioluminescent analysis system|
Methods and apparatus for evaluating the quality of an environment or process by measuring light emitted from a bioluminescent sample containing atp, adp, or alkaline phosphatase. The apparatus comprises a sample collection and analysis system used to collect a sample, mix reagents, react the sample, and collect it in a measurement chamber.
Biocontrol Systems, Inc.
|Genetic polymorphisms associated with rheumatoid arthritis, methods of detection and uses thereof|
The present invention is based on the discovery of genetic polymorphisms that are associated with rheumatoid arthritis. In particular, the present invention relates to nucleic acid molecules containing the polymorphisms, variant proteins encoded by such nucleic acid molecules, reagents for detecting the polymorphic nucleic acid molecules and proteins, and methods of using the nucleic acid and proteins as well as methods of using reagents for their detection..
|Genetic polymorphisms associated with cardiovascular disorders and drug response, methods of detection and uses thereof|
The present invention is based on the discovery of genetic polymorphisms that are associated with cardiovascular disorders, particularly acute coronary events such as myocardial infarction and stroke, and genetic polymorphisms that are associated with responsiveness of an individual to treatment of cardiovascular disorders with statin. In particular, the present invention relates to nucleic acid molecules containing the polymorphisms, variant proteins encoded by such nucleic acid molecules, reagents for detecting the polymorphic nucleic acid molecules and proteins, and methods of using the nucleic acid and proteins as well as methods of using reagents for their detection..
Bristol-myers Squibb Company
Probe reagent and fish using probe reagent
Provided are: a probe reagent which is capable of stably yielding a fluorescence signal in fish while inhibiting non-specific adsorption by the use of a nucleic acid molecule having a smaller number of bases than a bac probe; and fish using the probe reagent. The probe reagent is for in situ hybridization and comprises: phosphor-integrated nanoparticles containing phosphors integrated therein; and a nucleic acid molecule having a prescribed nucleic acid sequence, which phosphor-integrated nanoparticles and nucleic acid molecule are bound with each other..
Konica Minolta, Inc.
Lyophilized reagent, mixed reagent solution, and storing lyophilized reagent
A lyophilized reagent according to the invention is a lyophilized reagent for a nucleic acid amplification reaction obtained by lyophilizing a reaction mixture containing a reagent to be used for a nucleic acid amplification reaction and a sugar, wherein the sugar is contained in an amount of 72 mass % or more and 86 mass % or less with respect to the concentration of the solids contained in the lyophilized reagent.. .
Seiko Epson Corporation
Lyophilized material production method
A lyophilized material production method according to the invention is a lyophilized material production method for producing a lyophilized material by lyophilizing a reagent containing an additive at a lyophilization temperature, and includes a freezing step in which the reagent containing an additive is cooled with a low-temperature liquid whose temperature is lower than the lyophilization temperature, a maintaining step in which the temperature of the frozen reagent is increased to a temperature higher than the boiling point of the low-temperature liquid and the reagent is maintained at the temperature for a predetermined time, and a lyophilization step in which the reagent having been maintained for a predetermined time after increasing the temperature of the reagent is dried at the lyophilization temperature under reduced pressure.. .
Seiko Epson Corporation
Rapid detection of replicating cells
The invention enables efficient, rapid, and sensitive enumeration of living cells by detecting microscopic colonies derived from in situ cell division using large area imaging. Microbial enumeration tests based on the invention address an important problem in clinical and industrial microbiology—the long time needed for detection in traditional tests—while retaining key advantages of the traditional methods based on microbial culture.
Rapid Micro Biosystems, Inc.
Methods for the synthesis of functionalized nucleic acids
Described herein are methods for the synthesis of derivatives of thiosulfonate reagents. Said reagents have utility for the synthesis of phosphorothiotriesters from h-phosphonates in a stereospecific fashion..
Wave Life Sciences Ltd.
Polycationic methyl phospholipids for improveddelivery of nucleic acids to eukaryotic cells
New cationic lipids are provided that are useful for delivering macromolecules, such as nucleic acids, into eukaryotic cells. The lipids can be used alone, in combination with other lipids and/or in combination with other transfection enhancing reagents to prepare transfection complexes.
Molecular Transfer, Inc.
Asymmetric auxiliary group
The chiral reagent has following chemical formula (i). In the formula (i), g1 and g2 are independently a hydrogen atom, a nitro group (—no2), a halogen atom, a cyano group (—cn), a group of formula (ii) or (iii), or both g1 and g2 taken together to form a group of formula (iv)..
Methods and reagents for radiolabeling
The present invention provides methods for radiolabeling compounds useful as hsp90 inhibitors. The present invention also provides intermediates useful in such methods, and compositions of radiolabeled compounds.
Memorial Sloan-kettering Cancer Center
Methods for preparation of ammonium salts of c4 diacids by fermentation and integrated methods for making c4 derivatives thereof
Disclosed herein are methods for forming ammonium salts of c4 diacids in a fermentation process with simultaneous removal of divalent metal carbonate salts. The ph of fermentation broths obtained during the production of fumaric, maleic, malic, and/or succinic acid by a microorganism is controlled by using alkaline oxygen containing calcium or magnesium compounds in the hydroxide, oxide, carbonate or bicarbonate forms—forming divalent metal salts of the diacids that are partially or wholly insoluble in the broth.
Archer Daniels Midland Company
Sulfur enhanced nitrogen production from emission scrubbing
A fertilizer product is produced by a method of removing sulfur from flue gas. The method includes: introducing a flue gas stream to a wet scrubber; contacting the flue gas stream with a liquid nitrogen reagent in the wet scrubber that deposits in a bottom portion of the wet scrubber as a liquid fraction and possibly contacting the liquid fraction from the wet scrubber with an oxidizing gas; discharging reacted liquid nitrogen product from the wet scrubber that contains sulfur removed from the flue gas stream and that comprises a nitrogen and sulfur enriched fertilizer solution; and discharging flue gas exhaust from the wet scrubber..
Depression of copper and iron sulfides in molybdenite flotation circuits
A method of depressing copper sulfides and iron sulfides in a molybdenite floatation recovery process uses alkaline or alkaline earth polysulfides at high concentrate ph. The method of enriching molybdenite content from a slurry having molybdenite and at least one of iron sulfides and copper sulfides can include the steps of adding an effective amount of a depressing reagent selected from one or more alkaline poly sulfides, alkaline earth polysulfides, or a mixture thereof, to the slurry, wherein the ph of the slurry is greater than about 8.0; and passing a gas through the slurry to separate material by selective flotation, recovering the molybdonite from a froth..
Tessenderlo Kerley, Inc.
Microfluidics module and cartridge for immunological and molecular diagnosis in an analysis machine
The invention relates to a microfluidics module (100) for both the immunological and molecular diagnosis of samples, wherein channels (1, 3, 3′, 3″, 4, 7, 7′, 7″, 8, 8′) and/or cavities (2, 5) having inlets (1a, 1b, 3a-3i) for fluid samples and reagents, as well as inlet-assigned containers, container receiving means or container anchoring points are formed in a main body, and which module has a detection channel (80), for receiving a test-specific detection medium, that can be connected with channels (8, 7, 3) of the module. A central multi-port valve (6) is essential for the function, and controllably connects individual channels (3, 4, 7, 7′, 7″, 8) on the module.
Amodia Bioservice Gmbh
Reagent dispensing apparatus
A reagent dispensing apparatus includes a housing having a cavity with an opening and an aperture; and a plunger that includes a first member, that fits through the aperture, that is associated with a first seal. The plunger includes a second member associated with the first seal and a second seal that together form a first chamber, within the cavity, in which a first reagent is stored.
Point Of Care Diagnostics, Llc
Apparatus and a method to determine the concentration of an analyte
To determine a concentration of an analyte in a sample, a matrix impregnated with one or more reagents is contacted with the sample. Individual images of the matrix are captured.
Instrument and system for rapid microorganism identification and antimicrobial agent susceptibility testing
A system for automated microorganism identification and antibiotic susceptibility testing comprising a reagent cartridge, a reagent stage, a cassette, a cassette, stage, a pipettor assembly, an optical detection system, and a controller is disclosed. The system is designed to dynamically adjust motor idle torque to control heat load and employs a fast focus process for determining the true focus position of an individual microorganism.
Accelerate Diagnostics, Inc.
Anti-t. cruzi antibodies and methods of use
The present disclosure is directed to reagents and methods of using the reagents to detect epitopes of trypanosoma cruzi.. .
Electrochemical methods and devices for amending urine samples for immunosensor detection
The present invention is directed to methods and devices for amending undiluted and partially diluted urine samples in a manner suitable for performing immunoassays for target analytes, for example ngal. Generally, the urine sample is treated with reagents including at least one of buffer materials, water soluble proteins, urease, and other interferent mitigants.
Abbott Point Of Care Inc.
Test reagent, test reagent kit, and specimen measuring system
A test reagent includes a reactant and a sheet-shaped member. The reactant is in a dry state and specifically reacts with a test substance.
Toshiba Medical Systems Corporation
Apparatus for the automatic performance of immunohaematology analysis on gel cards
The apparatus has a containing body with a flat upper functional floor for containing receptacles of reagents, diluents and samples, as well as housings for gel cards and incubators for the same; a lower floor containing receptacles for washing liquids and the collection of waste and cards and for housing the fluid control and electronic control system; a series of longitudinal and transverse guides associated with the upper part of the apparatus, suitable for carrying in suspension the moving heads of the apparatus, the heads being movable on the transverse guides; two heads, respectively for perforation and pipetting and for the transport of gel cards; two centrifuges and a gel card reader; and a folding touch screen providing information and control.. .
Devices and kits for measuring biological results
The present invention relates to a kit and a device for measuring nucleic acid amplification through colour differentiation wherein said kit contains at least one ph indicator dye, one or more contained amplification reagents. The kit and device of the present invention also are used to detect, measure and/or record enzymatic reactions that result in ph changes.
Credo Biomedical Pte Ltd.
Multi-column separation apparatus and method
The invention provides an apparatus and system for the separation and optional analysis of the components of a sample of material, the apparatus and system comprising a cartridge comprising: at least one sample inlet port, at least one resin inlet port and a multiplicity of reagent and purge fluid input ports which are fluidically connected via a multiplicity of control valves to a multiplicity of chromatographic columns which are fluidically connected together in series; and a multiplicity of outlet ports wherein each outlet port additionally comprises an outlet valve which is adapted to control the flow of fluid through said outlet ports; wherein each of said multiplicity of chromatographic columns is aligned with one of said multiplicity of outlet ports so as to allow for fluid flow from said column through said outlet port. The system optionally additionally facilitates the analysis of the components.
National Nuclear Laboratory Limited
Reagent-free identification of bacteria containing resistance genes using a rapid intrinsic fluorescence method
This invention relates to a method that allows for the differentiation of isolates of commonly encountered bacteria that contain specific antibiotic-resistance genes from similar isolates that do not harbor the gene. More particularly, the invention relates to a method that utilizes an automated rapid platform system that employs intrinsic fluorescence, optical data analysis, and artificial intelligence methods to analyze multi-dimensional optical characteristics of bacterial strains..
Pocared Diagnostics Ltd.
Wetting detection without markers
The present invention relates to a method for evaluating the start of an assay in a fluidic chamber, wherein said start of the assay is based on the dissolving of a reagent in a region of interest in said fluidic chamber. The method may be based on the detection of an optical effect in the region of interest caused by the dissolving of the reagent, comprising the steps: obtaining an optical signal from one or more sub-sections of said region of interest; processing said optical signal to a boolean signal; and defining the start of the assay based on said boolean signal.
Koninklijke Philips N.v.
Vendor exclusivity security feature for paper-based diagnostic solution
Disclosed herein is a paper based diagnostic device including a portable biomedical diagnostic device comprising, paper, wax, and reagents. The biomedical diagnostic device can analyze biochemical assays in test fluids such as blood, urine, and saliva.
Apparatus and biological sample processing
An apparatus and method are described that achieve independent and simultaneous processing of a plurality of substrate-supported biological samples. In one embodiment, substrate holders arranged in a minor arc are independently moveable between a processing position and an access position, and reagents are delivered to substrates held in the substrate holders through a nozzle plate that moves along the arc of substrate holders.
Ventana Medical Systems, Inc.
In situ heat induced antigen recovery and staining apparatus and method
An automated in situ heat induced antigen recovery and staining method and apparatus for treating a plurality of microscope slides. The process of heat induced antigen recovery and the process of staining the biological sample on the microscope slide are conducted in the same apparatus, wherein the microscope slides do not need to be physically removed from one apparatus to another.
Methods, treatment, and compositions for characterizing thyroid nodule
The current disclosure provides, inter alia, method of determining benign nodules from thyroid cancer in a subject that is found to have a thyroid nodule, method of treating thyroid cancer in a subject detected to have thyroid cancer by the method of the current disclosure, compositions for determining benign nodules from thyroid cancer in a subject, and kits including reagents and composition for determining benign nodules from thyroid cancer in a subject.. .
City Of Hope
Genetic polymorphisms associated with psoriasis, methods of detection and uses thereof
The present invention is based on the discovery of genetic polymorphisms that are associated with psoriasis and related pathologies. In particular, the present invention relates to nucleic acid molecules containing the polymorphisms, including groups of nucleic acid molecules that may be used as a signature marker set, such as a haplotype, a diplotype, variant proteins encoded by such nucleic acid molecules, reagents for detecting the polymorphic nucleic acid molecules and proteins, and methods of using the nucleic acid and proteins as well as methods of using reagents for their detection..
Genetic polymorphisms associated with coronary events and drug response, methods of detection and uses thereof
The present invention provides compositions and methods based on genetic polymorphisms that are associated with coronary heart disease (particularly myocardial infarction), aneurysm/dissection, and/or response to drug treatment, particularly statin treatment. For example, the present invention relates to nucleic acid molecules containing the polymorphisms, variant proteins encoded by these nucleic acid molecules, reagents for detecting the polymorphic nucleic acid molecules and variant proteins, and methods of using the nucleic acid molecules and proteins as well as methods of using reagents for their detection..
Amplification and detection of nucleic acids
The present disclosure relates to a sample assessment device. By way of example, the sample assessment device may include a substrate including a sample application region; an amplification region comprising a plurality of amplification reagents; a waste region comprising an entrance fluidically coupled to the amplification region and extending away from the amplification region; and a detection region spaced apart from the amplification region.
University Of Washington
Multi-channel optical measurement instrument
A receptacle having a plurality of interconnected chambers arranged to permit multiple process steps or processes to be performed independently or simultaneously. The receptacles are manufactured to separate liquid from dried reagents and to maintain the stability of the dried reagents.
Luminescence measurement of biologial samples utilizing dual reagents
In a method for measuring luminescence of a biological sample utilizing two different luminescence reagents, the sample is agitated to improve mixing with the second luminescence reagent, allowing for a shorter delay time between injection of the second reagent and measurement of the resulting luminescence activity. The improved mixing may also allow for a shorter measurement time, thereby improving throughput when assaying a large number of samples..
Molecular Devices, Llc
Compositions and methods for dna and rna extraction from tissue samples
Methods and reagents are provided for the rapid extraction of nucleic acids from a cell or tissue sample. In certain embodiments the sample comprises a formalin fixed paraffin embedded sample (e.g., a ffpet sample), or a fine needle aspirate and/or a cell/tissue smear.
Mesofluidic reactor with pulsing ultrasound frequency
A mesofluidic reactor performs a chemical reaction of a starting material. A liquid phase starting material is introduced into a spraying head equipped with an ultrasound generating piezoelectric crystal unit.
Composition and rapidly inducing an endogenous ketosis
A composition and method for rapidly inducing a state of endogenous ketosis, the composition including: about 26.66-28.57 percent by mass of alpha lipoic acid; about 0.01-0.02 percent by mass of chromium picolinate; about 47.61-49.99 percent by mass of l-arginine; and, about 23.33-23.81 percent by mass of calcium carbonate. The method includes restricting carbohydrate consumption to a maximum dosage of about 20 grams prior to consumption of the composition and wherein consumption of the composition is on an empty stomach.
Method for inner-contour passivation of steel surfaces of nuclear reactor
A method for the inner-contour passivation of steel surfaces of a nuclear reactor consists in filling a first contour of a nuclear reactor with a liquid metal coolant, introducing a reagent into the liquid metal coolant, said reagent interacting with the material of elements of the first contour, forming a protective film, and heating the liquid metal coolant, having the reagent introduced therein, to a temperature allowing for conditions for forming the protective film. The liquid metal coolant having the reagent introduced therein is kept at said temperature until a continuous protective film is formed on the surface of the material of the elements of the first contour.
Joint Stock Company "akme-engineering"
Magnetic particle tagged reagents and techniques
Surfaces specifically coated with reactants are reactive with the moi in the tagged magnetic particle complex and of buoyant or other forces are used to remove any unbound material from the surface before reading. Readable labels, in addition to the magnetic particle tagged complex itself, such as enzymes, fluorophors, chemiluminescent materials, radioactive isotopes, chromogenic and fluorogenic substrates and other labels may be used.
Diagnostic reagents for improved in vivo or in vitro cell-mediated immunological diagnosis of tuberculosis
The present invention discloses in vitro and in vivo diagnostic methods with enhanced specificity and sensitivity for the detection of tuberculosis. The diagnostic re agents of the present invention can replace former mixtures/cocktails/pools of antigens comprising esat-6 but including esat6 improves the diagnosis even further..
Statens Serum Institut
Apparatus and electrical detection of oligonucleotides through pore blockades
Systems and methods for specific nucleic acid (na) sequence detection that do not rely on polymerase chain reaction (pcr) for target sequence amplification and do not require any special reagents other than a complementary sequence capture probe conjugated to spherical beads.. .
The Regents Of The University Of California
A test strip includes a substrate, a spacer layer having a notch, a reagent layer, a support layer, and a cover layer having a covering portion covering the notch and a channel portion extending rearward from the covering portion corresponding to a rear end of the notch. The substrate is attached under the spacer layer and has a reaction region exposed from the notch.
Tyson Bioresearch Inc.
Airborne microbial measurement apparatus and measurement method thereof
An airborne microbial measurement apparatus and a measurement method thereof are provided. An airborne microbial measurement apparatus according to an embodiment includes a discharge apparatus including a discharge electrode and a voltage supply unit applying a high voltage to the discharge electrode.
National University Corporation Toyohashi University Of Technology
Disposable, integrated microfluidic cartridge and methods of making and using same
The disclosed embodiments concern microfluidic cartridges for detecting biological reactions. In some embodiments, the microfluidic cartridges are configured to perform sequencing operations on a nucleic acid sample.
Apparatus for use in isothermal amplification
A method of monitoring amplification of a nucleic acid by providing a nucleic acid and an amplification mixture using the kit of isothermal reagents to a ph sensor or ph indicator,. .
Dnae Group Holdings Limited
Test strip and measuring the content of alcohol in blood, or of any other substance in blood, and a measuring the content of alcohol in blood
A test strip for measuring the blood alcohol content from blood includes a base material and two electrodes attached to it and a reaction area connected to both electrodes, to which area nicotin—amide adenine dinucleotide (nad+) and alcohol dehydrogenase enzyme (adh) are applied as reagents. A sample opening is connected to the reaction area, from which opening the blood sample to be measured can be transferred to the reaction area to dissolve the reagents and optional auxiliary substances, and at the same time into contact with both electrodes.
Pal Finland Oy