|| List of recent Reagent-related patents
| Medications directing system and method with cloud server|
A monitoring system includes a cloud server, a first terminal, a second terminal, and a third terminal. The first, second and third terminal are connected to the cloud server.
Hon Hai Precision Industry Co., Ltd.
| Iodination process for the preparation of 3, 5-disubstituted-2, 4, 6-triiodo aromatic amines compounds|
The invention discloses a improved process for the preparation of 3,5-disubstituted-2,4,6-triiodo aromatic amines of formula (ii), wherein r1 and r2 are defined as herein. The compounds of formula (ii) are the key intermediates for the synthesis of a series of non-ionic contrast agents such as iopamidol, iohexol and iodixanol.
Imax Diagnostic Imaging Holding Limited
| Process for the synthesis of urea comprising a passivation stream at the stripper bottom|
A process for the direct synthesis of urea from ammonia and carbon dioxide with increased corrosion resistance, comprising, in the high-pressure synthesis section, a reaction step in a vertical reactor fed with at least one stream of fresh carbon dioxide containing a passivating agent and a decomposition-stripping step of the non-converted reagents, wherein the gas-liquid mixture collected at the head of the reactor is separated into a gaseous stream and a liquid stream fed to the tail and head of the stripper, respectively.. .
| Method for preparing dipeptidyl peptidase-iv inhibitor and intermediate|
The present invention relates to an improved method for preparing dipeptidyl peptidase-iv inhibitor and intermediate. The present invention is able to reduce preparation costs by using low cost reagents on reaction and is able to be used in mass production by improving yield..
Dong-a Pharmaceutical. Co., Ltd
| Monoclonal antibody for analyzing high-molecular weight adiponectin and utilization of same|
A monoclonal antibody that does not show a crossreactivity with middle-molecular weight (mmw) adiponectin and specifically reacts with high-molecular weight (hmw) adiponectin alone is disclosed. The monoclonal antibody of the present invention can be produced by using hmw adiponectin as an antigen.
Lsi Medience Corporation
| Compositions and methods of detecting and treating neural tube defects|
The present invention generally relates to compositions, reagents and methods for detecting and treating a neural tube defect in a fetus. One aspect of the invention provides a method including administrating a composition containing noggin or ldn-193189 to the fetus in utero.
Ann And Robert H. Lurie Children's Hospital Of Chicago
| Method for amplifying cdna derived from trace amount of sample|
The problem to be solved by the present invention is to provide a method for preparing a sample for comprehensively and accurately analyzing gene expression in a single cell or a few cells, for example, by a large-scale dna sequencer. The present invention relates to a method for amplifying cdna from mrna in a cell, comprising: (1) capturing mrna derived from the cell by a first dna probe containing a first tag sequence and a poly t sequence and being immobilized to a solid carrier in a single reaction vessel, and synthesizing a first strand cdna from the mrna by a reverse transcription reaction; (2) removing a reaction reagent from the reaction vessel while keeping the first strand cdna synthesized onto the solid carrier in the reaction vessel; (3) adding a polynucleotide sequence consisting of one type of nucleotides to 3′ terminal of the first strand cdna on the solid carrier; (4) hybridizing a second dna probe containing a second tag sequence and a complementary sequence to the polynucleotide sequence with the cdna to which the polynucleotide sequence is added, and synthesizing a second strand cdna; and (5) performing a dna amplification reaction using the second strand cdna synthesized on the solid carrier as a template..
| Method of quantifying peptide-derivative libraries using phage display|
The present application provides a method of quantifying an amount of a derivatized peptide displayed on a phage by phage display, the method comprising: providing a phage containing the target peptide thereon; reacting the phage containing the target peptide with a first reagent to derivatize the target peptide to form a derivatized peptide, reacting the derivatized peptide with a capture agent comprising a detection marker, thereby incorporating the detection marker within the derivatized peptide; and determining an amount of the detection marker, thereby quantifying the amount of the derivatized peptide displayed on the phage. A kit comprising a capture agent comprising a detection marker for quantifying the phage displayed derivatized peptides is also provided..
The Governors Of The University Of Alberta
| Release reagent for vitamin d compounds|
A reagent composition for releasing vitamin d compounds bound to vitamin d-binding protein, an in vitro method for the detection of a vitamin d compound in which the vitamin d compound is released from vitamin d-binding protein by the use of this reagent composition and the reagent mixture obtained in this manner. The use of the disclosed reagent composition to release vitamin d compounds as well as a kit for detecting a vitamin d compound which contains the reagent composition for releasing vitamin d compounds in addition to common detecting reagents..
Roche Diagnostics Operations, Inc.
| Methods and compositions for detection and analysis of polynucleotides using light harvesting multichromophores|
Methods, compositions and articles of manufacture for assaying a sample for a target polynucleotide are provided. A sample suspected of containing the target polynucleotide is contacted with a polycationic multichromophore and a sensor polynucleotide complementary to the target polynucleotide.
The Regents Of The University Of California
Biosensor chip, and biosensor device equipped with same
This biosensor chip is placed in a biosensor device and is rotated while a specimen is measured, the biosensor chip comprising a main body, a holding chamber, a dispensing chamber, a plurality of quantification chambers, and a plurality of measurement chambers. The main body has an inlet into which a biochemical analysis specimen is poured.
Panasonic Healthcare Co., Ltd.
Blood cell counting device and method
A device for use in imaging a liquid sample comprises an inlet for accepting the sample, a connection conduit and a detection chamber for detection of the sample, preferably optical detection of the sample. The connection conduit connects the inlet to the detection chamber and contains one or more dry reagents for reaction with the sample as the sample passes through the connection conduit.
Chromatographic isolation of cells and other complex biological materials
The present invention relates to the chromatographic isolation of a target cell or another complex biological material, in particular by column chromatography such as affinity chromatography or gel permeation chromatography. The invention employs a receptor binding reagent that binds to a receptor molecule that is located on the surface of a target cell.
Stage Cell Therapeutics Gmbh
Method for determining the glycosylation of an antibody
The invention relates to a method for detecting the binding of an antibody to an fc receptor present on the surface of a cell as well as to a method for determining the level of glycosylation of an antibody. The invention also relates to a reagent kit for carrying out these methods..
Sequential delivery device and method
A reagent delivery device includes a reagent delivery column with a housing receiving reagent storage elements that can move, and a breaching element coupled to the housing. The device includes an actuation member that during operation forces the reagent storage elements toward the breaching element.
Immunogenic compositions and reagents for preparing
The invention described herein pertains to compounds and conjugates, to compositions, complexes and formulations comprising the compounds and/or conjugates, and to methods of use of the compounds, conjugates and their compositions, complexes and formulations in vaccines and vaccinations and generating immune responses.. .
Purdue Research Foundation
Antibody polypeptides that antagonize cd40l
Antibody polypeptides that specifically bind human cd40l are provided. The antibody polypeptides do not activate platelets.
Methods and pasadena hyperpolarization
The present subject matter relates to methods and apparatus for using hyperpolarization to improve imaging. Am exemplary embodiment, a pasadena polarizer, is capable of delivering 2.5-5 ml of highly hyperpolarized biological 13c and 15n imaging reagents in less than one minute, and capable of repeated delivery every 5-8 minutes.
Huntington Medical Research Institutes
Near-field-communication or rfid based electrochemical biosensor and an ingredient measurement using thereof
Disclosed herein are a near-field-communication or a radio-frequency identification (rfid) based electrochemical biosensor capable of measuring an ingredient by being inter-worked with a wireless communication device such as a smartphone and a method for an ingredient measurement using thereof. The near field communication or radio-frequency identification based electrochemical biosensor, includes: a casing having a specimen introduction channel formed therein; an ingredient measurement electrode disposed in the casing and measuring a specific ingredient of a specimen; a reaction reagent portion disposed in the casing and reacting with the specimen; a specimen recognition electrode disposed in the casing and recognizing the introduction of the specimen; an antenna transmitting and receiving signals and power to and from a smart device or a tester; and a control integrated circuit (ic) chip controlling the ingredient measurement electrode, the specimen recognition electrode, and the antenna..
Center For Integrated Smart Sensors Foundation
Process for producing renewable bioproducts from various feedstocks
The present invention describes a method for production of a class of renewable specialty chemicals that may be used for a variety of purposes including as a solvent in the semiconductor industry and as a reagent for commercial chemical production. The precursor compound, pha, can be produced using various feedstocks such as waste water treatment plant biosolids, distiller's grains and agricultural residual biomass (e.g., corn stover and rice straw).
Process for preparation of dronedarone by the use of dibutylaminopropanol reagent
The invention relates to a novel process for preparation of dronedarone of formula (i) and pharmaceutically acceptable salts thereof, characterized in that a compound of formula (ii)—where l is leaving group—is reacted with compound of formula (iii) and the obtained product is isolated and, if desired, converted into a pharmaceutically acceptable salt thereof.. .
Process for preparing transition metal-carbene complexes
Process for preparing cyclometallated transition metal-carbene complexes comprising at least one carbene ligand, which comprises reacting a ligand precursor with a base, an auxiliary reagent and a metal complex comprising at least one metal m1 (route a) or reacting the ligand precursor with a basic auxiliary reagent and a metal complex comprising at least one metal m1 (route b). The present invention further relates to the use of an auxiliary reagent selected from among salts comprising at least one metal selected from the group consisting of ag, hg, sb, mg, b and al together with a base in a process for preparing cyclometallated metal complexes..
Method of manufacturing biomedical molecular detection platform and the detection platform manufactured therefrom
The present invention provides a method of manufacturing biomedical molecular detection platform, comprising providing a plurality of reagent droplets on a first surface of a substrate; forming a plurality of hydrophilic regions and a water-repellant region on a second surface of a test paper, and the plurality of hydrophilic regions separated individually by the water-repellant region; and contacting the first surface of the substrate with the second surface of the test paper for transferring each reagent droplet on the substrate to each hydrophilic region of the test paper. The present invention also provides a biomedical molecular detection platform manufactured therefrom.
National Tsing Hua University
Lipid arrays on fabricated devices and uses thereof
Systems and methods for arranging microdevices on an array substrate are described. Each microdevice contains a lipid bilayer region and a patterned magnetic material that has a predetermined preferential axis of magnetization.
Reagents and methods for detecting protein lysine 2-hydroxyisobutyrylation
The invention provides an isolated peptide comprising a lysine 2-hydroxyisobutyrylation site, a lysine 2-hydroxyisobutyrylation specific affinity reagent that specifically binds to the peptide, and a method for detecting protein lysine 2-hydroxyisobutyrylation in a sample using the reagent.. .
Ptm Biolabs, Inc.
Method for detecting the presence of a target nucleic acid sequence in a sample
A method comprises loading a sample portion into a sample chamber which comprises means for minimizing diffusion of the sample portion, subjecting the sample portion to an amplification step, and determining whether the sample portion contains at least one molecule of a target nucleic acid. If the sample portion contains a single molecule of the target nucleic acid, the sample portion would attain a detectable concentration of the target nucleic acid after a single round of amplification.
Health And Human Services, United States Of America, As Represented By The Secr
Method of exosome analysis, reagent for exosome analysis, and analyzer for exosome
The method of exosome analysis of the present invention is a method of analyzing exosome in a sample, including: an addition step of adding a first antibody that specifically binds to a first antigen contained in the exosome and a second antibody that specifically binds to a second antigen contained in the exosome to the sample; a reaction step of causing the first antigen to be reacted with the first antibody and the second antigen to be reacted with the second antibody; and a detection step of detecting a reaction between the first antigen and the first antibody and a reaction between the second antigen and the second antibody.. .
Reagents and methods for autoligation chain reaction
The invention relates to the amplification of specific target nucleic acids. The invention provides methods, reagents, and kits for carrying out such amplification via the autoligation chain reaction (acr)..
Method for fabricating microchip for nucleic acid amplification reaction
Provided is a method for fabricating a microchip for nucleic acid amplification reaction that is capable of simple and highly accurate analysis. Provided is a method for fabricating a microchip for nucleic acid amplification reaction, the method including a solidification step of drying a reagent solution including at least a part of substances required for a nucleic acid amplification reaction, and a containment step of arranging the reagent solution including the solidified substance in wells that serve as a reaction site for a nucleic acid amplification reaction.
Novel crosslinking reagents, macromolecules, therapeutic bioconjugates, and synthetic methods thereof
The invention provides novel chemical entities based on sugar alcohols. These new chemical entities are biocompatible and biodegradable.
Site-specific chemoenzymatic protein modifications
The present invention relates to methods and reagents for use in site-selective modification of proteins having lysine residues with functionalized peptides using a chemoenzymatic microbial transglutaminase-mediated reaction. The functionalized proteins may be used for study or therapeutic uses..
Micro-sensor based test apparatus
There is provided a fluid test strip, comprising a micro-sensor formed on a substrate surface and a reagent deposition site formed on the substrate surface, operate to control the size and location of a reagent deposition. There is also provided a method of forming fluid test strip, comprising forming a micro-sensor on a substrate surface and forming a reagent deposition site on the substrate surface, operable to control the size and location of a reagent deposition..
Methods for recovering and/or removing reagents from porous media
A composition and method for displacing, dissolving, extracting, recovering, and/or removing solvent and/or any solvent-associated liquids from a solvent-treated material or penetrating through pores or the surface of a solvent-treated material using a solvent-extracting composition for contacting solvent-treated material and separating the solvent and any solvent-associated liquids from the solvent-treated material as well as the solvent-extracting composition.. .
Green Source Energy Llc
Analysis system, analysis device, and management device
An analysis system comprising: an analysis device that analyzes a sample using a reagent and that performs the analysis of the sample in accordance with a measurement parameter measured in relation to a reagent to be used; and a management device communicably connected to the analysis device via a network; wherein the analysis device includes a first control unit that enables execution of processing for accepting a registration of the measurement parameter, and when the measurement parameter is registered, executes processing for transmitting to the management device transmission information including information indicating that the measurement parameter is registered; and the management device includes a second control unit that executes a receiving process of receiving the transmission information transmitted from the analysis device and an output process of outputting information indicating that the measurement parameter is registered in the analysis device based on the received transmission information is disclosed.. .
Process for preparing organic-inorganic hybrid silicates and metal-silicates with an ordered structure and new hybrid silicates and metal-silicates
The present invention relates to a process for the preparation of organic-inorganic hybrid silicates and metal-silicates of the ecs type which uses as starting material the corresponding disilanes: said process is characterized by the presence of boric acid in the reagent mixture. With the process of the invention, ecs silicates and metal-silicates are obtained, characterized by an x-ray diffractogram with reflections exclusively at angular values higher than 4.0° of 2Θ, and characterized by an ordered structure which contains: —structural units having formula (a), wherein r is an organic group: —boron—one or more elements t, different from boron, selected from groups iiib, nb, vb, and transition metals, with a molar ratio si/(si+t) in said structure greater than 0.3 and lower than 1, wherein si is the silicon contained in the structural unit having formula (a).
Difluoromethylation of unsaturated compounds
A reagent for carrying out a difluoromethylation reaction of unsaturated compounds and ring-nitrogen-containing aromatic compounds, a zinc difluoro-methanesulfinate, as well as a method for making the reagent and a method for its use are disclosed.. .
The Scripps Research Institute
Biosourced epoxide resins having improved reactivity
Biosourced epoxide resins are provided, including the product of the reaction of one or more biosourced epoxide lipid derivatives with at least one cross-linking agent in the presence of at least one co-reagent selected from among the glycidyl ether derivatives of biosourced polyols or the product of the reaction of one or more glycidyl ether derivatives of biosourced polyols with at least one cross-linking agent.. .
Centre National De La Recherche Scientifique
Detection chip and using the same
A detection chip is provided. The detection chip includes a substrate, an active reagent, a hydrophilic droplet and a lipophilic substance.
Industrial Technology Research Institute
System and detection of target substances
A system and method for detecting harmful substances within a consumable sample comprising: receiving a consumable sample at a first chamber of a test container; transforming the consumable sample into a homogenized sample upon processing of the consumable sample; delivering the homogenized sample to a second chamber of the test container, wherein the second chamber is configured to receive the homogenized sample comprises an outlet port; mixing the homogenized sample with a process reagent within the second chamber, thereby producing a dispersion; transmitting a volume of the dispersion to an analysis chamber, of the test container, configured to position a detection substrate proximal the port of the second chamber and comprising a detection window that enables detection of presence of the allergen; and detecting presence of the allergen within the consumable sample by way of an optical sensor configured to detect signals indicative of the allergen through the detection window.. .
A bio-sensing device includes a first platform, a second platform, at least one first magnetic element, and at least one second magnetic element. The first platform is configured to support a microplate.
Reagents, kits and methods, for detecting biological molecules by energy transfer from an activated chemiluminescent substrate to an energy acceptor dye
Reagents, kits and methods for detecting biological molecules by energy transfer from an activated chemiluminescent substrate to an energy acceptor dye such as a j-aggregated dye are described.. .
Applied Biosystems, Llc
Immunochromatographic assay with minimal reagent manipulation
The present invention provides a method for determining the presence or absence of an analyte in a sample with minimal sample preparation. The invention further provides immuno-chromatographic devices for determining the presence or absence of an analyte in a sample from which the analyte should be extracted, this device comprising an analyte extraction zone wherein one or more mobile extraction solutions are impregnated, and wherein at least one of said extraction solutions comprises an animal serum or plasma component..
Transparent conductive electrodes comprising merged metal nanowires, their structure design, and making such structures
A method for making a nanowire-based electrode having homogenous optical property and heterogeneous electrical property is disclosed. The method comprises coating a first solution comprising a first material on to the substrate to form a layer of nanowire network; evaporating to remove the solvent in the metal nanowire film; printing a second solution comprising a chemical reagent on top of the formed metal nanowire network layer; and oxidizing the first material into a second material by the chemical reagent, wherein the first material and second material has a refractive index difference less than 0.05 and second material is less conductive than the first material..
Nuovo Film, Inc.
Translocation and mutant ros kinase in human non-small cell lung carcinoma
In accordance with the invention, a novel gene translocation, (5q32, 6q22), in human non-small cell lung carcinoma (nsclc) that results in a fusion proteins combining part of cd74 with proto-oncogene tyrosine protein kinase ros precursor (ros) kinase has now been identified. The cd74-ros fusion protein is anticipated to drive the proliferation and survival of a subgroup of nsclc tumors.
Cell Signaling Technology, Inc.
High-efficiency solar water splitting by nanocrystalline cobalt (ii) oxide photocatalyst and uses thereof
In an embodiment, the present disclosure pertains to photocatalysts with high solar-to-hydrogen overall water splitting efficiency. In an embodiment, the photocatalyst is a nanocrystalline cobalt (ii) oxide (coo) nanoparticle.
University Of Houston
Apparatus and methods for the preparation of reaction vessels
Provided are methods for preparing and using reaction vessels obtained or obtainable by 3d-printin methods, including a method for preparing a product compound, the method comprising the steps of: (i) providing a reaction vessel that is obtained by a 3-d printing method, wherein the reaction vessel has a reaction space; (ii) providing one or more reagents, optionally together with a catalyst or a solvent, for use in the synthesis of the product compound; and (iii) permitting the one or more reagents to react in the reaction space, optionally in the presence of the catalyst and the solvent, in the reaction vessel, thereby to form the product compound.. .
The University Court Of The University Of Glasgow
Reagent container for biological sample analyzer and manufacturing reagent container
A reagent container for a biological sample analyzer that has higher impact resistance than a conventional one and a method for manufacturing the reagent container are provided. The reagent container for a biological sample analyzer is formed of a paper sheet member and has a bottom surface and side wall surfaces connected to the bottom surface.
To provide an automated analyzer adapted for accommodating a larger number of reagent cassettes to meet calls for increases in analytical throughput and in the number of analytical items, and thus using the accommodated reagent cassettes more efficiently. An automated analyzer body 100 includes a main reagent buffer 4 for storing a plurality of reagent cassettes each containing a reagent used for analysis and a subsidiary reagent buffer 12.
Hitachi High-technologies Corporation
Generation of reagent ions for ion-ion reactions
An apparatus, system and method of providing that allow for the generation of reagent ions within an inner region of a mass spectrometer for use in ion-ion reactions such as ptrs and etd using a reagent ion generator. The location where these reagent ions are generated can be as close as possible to the point of action, or the reaction zone where the reagent ion and analyte ions will interact via ion-ion reactions to cause, e.g., ptrs and/or etd..
Dh Technologies Development Pte. Ltd.
Pneumatically/hydraulically actuated fluoropolymer-hplc chromatographic system for use with harsh reagents
The invention provides a high-performance liquid chromatography system, said system is controlled in temperature by running a fluid in sleeves that surround the different parts of the system. All parts in contact with the fluid are made in fluoropolymer, carbon-filled fluoropolymer, or carbon-fiber fluoropolymer.
Orlab Chromatography, Llc
Method of using an electrochemical test sensor
A method of distinguishing a control solution from a sample in an electrochemical test sensor is performed. The method includes adding a control marker to the control solution.
Bayer Healthcare Llc
Reagent composition for biosensor and biosensor having the same
This invention discloses a reagent composition for a biosensor having high sensitivity which is capable of improving analysis linearity of an analyte such as glucose by reacting an oxidoreductase, a metal-containing complex, and naphthol green b, and minimizing blood necessary for measuring blood glucose since it is possible to detect a concentration of a small amount of the analyte, and a biosensor having the same. The reagent composition for a biosensor includes at least two kinds of electron transfer mediators including naphthol green b, and an enzyme..
Infopia Co., Ltd.
Multiplex slide plate
The present invention relates to a multiplex slide plate for various types of assays. The slide plate may be pre-filled with special-formulated reagents in different reaction zones, and the reactions carry out independently in the reaction zones filled with special-formulated reagent..
Sample processing device with detachable slide
A biological and chemical sample processing device that b. Comprises a high pressure-resistant, shallow and wide area microfluidic chamber having at least one wall formed by a detachable slide containing samples such as immobilized entities, biological samples or molecules, c.
Ecole Polytechnique Federale De Lausanne (epfl)
Compositions and methods for analyte detection
The inventions provided herein relate to detection reagents, compositions, methods, and kits comprising the detection reagents for use in detection, identification, and/or quantification of analytes in a sample. Such detection reagents and methods described herein allow multiplexing of many more labeled species in the same procedure than conventional methods, in which multiplexing is limited by the number of available and practically usable colors..
President And Fellows Of Harvard College
Reagents for oxidizer-based chemical detection
Reagents and methods are disclosed for detection of oxidizers and inorganic salts and other analytes of interest. The reagents can interact with their target analytes, especially oxidizer compositions or oxidizer-based explosives, to selectively enhance their ionization yield, interacting by chemical reaction or by forming an associative adduct which facilitates their detection.
Massachusetts Institute Of Technology
Luminescence detection method
A method of detecting an analyte is provided. The method includes providing a sample, a container 110 with a wall 115, and a catalyst for a luminescent reaction.
3m Innovative Properties Company
Modified planar cell (mpc) and electrochemical device battery (stack) based on mpc, manufacturing planar cell and battery, and planar cell embodiments
The invention relates to a modified planar cell with a solid-oxide solid electrolyte, a gas-diffuse anode, a cathode, a metal or oxide current path and a current-gas supply. The supporting solid electrolyte of the cell is in the form of a corrugated plate consisting of corrugations.
Device for heating a heat engine of a vehicle
The invention relates to a device for heating the heat engine (7) of a vehicle, comprising: a reactor (3) in which a reagent that can cause an exothermic reaction with a reaction fluid is disposed, a circuit (5) for supplying reaction fluid to the reactor (3), a heat-exchange circuit (8) between the reactor (3) and the heat engine (7) of the vehicle, and a circuit (9) for regenerating the reagent.. .
Valeo Systemes De Controle Moteur
Apparatus for administering fluid to a medical tube
An apparatus 100 for use in tube feeding comprises a cylindrical body 110 provided with a first opening 120 and a second opening 130 connected by a flow channel 140. The body 110 comprises reagent 111, for determining a characteristic of fluid disposed in the body and a transparent window 112 through which the reagent 111 is visible.
Cme Uk (holdings) Limited
Oxidation decontamination reagent for removal of the dense radioactive oxide layer on the metal surface and oxidation decontamination method using the same
The present invention provides an oxidative decontamination reagent for removal of the dense radioactive oxide layer on a metal surface, which comprises an oxidizing agent, a metal ion, and an inorganic acid. The oxidative decontamination reagent of the present invention is characteristically prepared by adding a metal ion to the conventional oxidative decontamination reagent containing an oxidizing agent and an inorganic acid.
Korea Atomic Energy Research Institute
Methods of responding to a biothreat
The present disclosure provides for devices, in particular mobile devices, which may be used in the synthesis of modified nucleic acid molecules, in particular modified mrna molecules. The device for making the modified nucleosides, modified nucleotides and modified nucleic acids (e.g., mrna) disclosed herein may be mobile devices comprising at least one sample block for insertion of one or more sample vessels, a device base with electronic control units for the sample block, a voltage supply, and one or more reagent(s) for the synthesis of at least one nucleic acid..
Moderma Therapeutics, Inc.
Microfluidic particle-analysis systems
The invention provides systems, including apparatus, methods, and kits, for the microfluidic manipulation and/or detection of particles, such as cells and/or beads. The invention provides systems, including apparatus, methods, and kits, for the microfluidic manipulation and/or analysis of particles, such as cells, viruses, organelles, beads, and/or vesicles.
Assay cartridges and methods of using the same
Assay modules, preferably assay cartridges, are described as are reader apparatuses which may be used to control aspects of module operation. The modules preferably comprise a detection chamber with integrated electrodes that may be used for carrying out electrode induced luminescence measurements.
Meso Scale Technologies, Llc
Health test for a broad spectrum of health problems
Provided herein are methods and devices for the detection of conditions or disorders by detecting altered levels of stress response pathway biomarkers. Also provided are methods and reagents for identifying panels of biomarkers associated with a condition or disorder..
Method for inserting genetic material into genomic dna
The present invention provides reagents and methods for improved homologous recombination.. .
Arizona Board Of Regents, A Body Corporate Of The State Of Arizona, Acting For And On Behalf Of Ariz
Microfluidic apparatus, method, and applications
A microfluidic apparatus, method, and associated applications utilize and apply to a formalin-fixed paraffin-embedded (ffpe) tissue sample and performing a liquid-liquid extraction to remove the paraffin from the tissue sample prior to a nucleic acid purification step. A microfluidic device includes a dedicated liquid-liquid extraction process vessel, a nucleic acid purification process component, and a nucleic acid amplification reactor.
To be adapted to various types of latex reagents for detecting scattered light and thereby measuring agglutination reactions with high sensitivity while sufficiently ensuring integration time. To be adapted to various types of latex particles of different particle sizes, a plurality of light receivers are arranged in a plane perpendicular to the direction of cell movement by rotation of a cell disk.
Hitachi High-technologies Corporation
A reagent including a combination of a polyanionic compound and a bivalent cationic compound contains one substance selected from the group consisting of succinic acid, gluconic acid, alanine, glycine, valine, histidine, maltitol, and mannitol or at least one compound of the substance. A dry state of the reagent and deliquescence can be improved..
Panasonic Healthcare Co., Ltd.
Blood glucose measurement unit, blood glucose measurement system comprising the same, and blood glucose measurement method
A blood glucose measurement unit, a blood glucose measurement method, and a blood glucose measurement system comprising the same are disclosed. According to one aspect of the present invention, provided is a blood glucose measurement unit comprising: a transparent first substrate consisting of a blood inflow region into which blood flows and a reaction region connected to the blood inflow region which are formed on one surface thereof; a transparent second substrate coupled to the first substrate and comprising a blood aperture through which the blood flowing into the blood inflow region passes; and a reagent distributed to the reaction region so as to react with the blood glucose of the blood which has flown into the blood inflow region..
Gachon University Of Industry - Academic Cooperation Foundation
Three dimensional lignocellulosic detection device
A three dimensional lignocellulosic detection device includes a first lignocellulosic substrate and a second lignocellulosic substrate. When the first lignocellulosic substrate is in contact with a liquid specimen through capillary effect, the sample is absorbed into the second lignocellulosic substrate through the first lignocellulosic substrate, reacts with the detecting reagent on the second lignocellulosic substrate and makes a detection test.
National Tsing Hua University
Assembly for selectively performing a clinical chemistry test or an elisa assay, use of said reagent cartridge and assembly
An assembly for selectively performing a clinical chemical test or an elisa assay including a reagent cartridge with a housing 11 having at least one cavity 12, 13, 14 that contains a reaction or diluting component and having a recess 15 in which a solid phase 20 to which an antigen or antibody can be coupled is inserted into the recess 15 of the housing 11. The assembly also includes at least one measuring cell, wherein a measuring cell is assigned to each reagent cartridge and wherein the reagent cartridge and the measuring cell assigned to it are in a linear assembly in an analytical device..
Drg Instruments Gmbh
Device and carrying out haematological and biochemical measurements from a biological sample
The present invention concerns a device for analyzing biological parameters from a sample (6) comprising (i) first transferring means (5, 20, 25), (ii) first preparing means (7), (iii) means for measuring cellular components (8), (iv) second preparing means (10, 11, 22, 23, 24) capable of carrying out, on a sample from the first preparing means (7), at least one dilution with an assay reagent (r3) comprising particles functionalized at the surface with at least one ligand specific to at least one analyte of interest, (v) immunodetection measurement means (30, 31) capable of assaying at least one analyte of interest by measuring the aggregation of functionalized particles, said device further comprising (i) second transferring means (4, 21, 22, 26) at least partially separate from the first transferring means (5, 20, 25) and (ii) means for applying a magnetic field (28) capable of causing, by magnetic interaction, an acceleration of the aggregation of said functionalized particles, which comprise magnetic colloidal particles. The invention also concerns a method implemented in said device..
Horiba Abx Sas
Reagent reservoir system for analytical instruments
The invention provides a reagent reservoir system and disposable reaction cassettes using the same. In one aspect, such system comprises a chamber in which dried reagent, particularly lyophilized reagent, is constrained to remain in a defined region of the chamber by a retaining member that obstructs passage of such reagents to other regions of the chamber where they may escape hydration or activation..
Metronidazole resistance in trichomonas vaginalis and single nucleotide polymorphisms
The present invention is directed to the discovery of single nucleotide polymorphisms (snps) in the presence of metronidazole-resistant trichomonas vaginalis. The presence of g76c, c213g, or c318a (snp) in tvntr 4 or the presence of a238t, g427c, or t476c (snp) in tvntr6 provides a reliable biomarker for the presence of metronidazole-resistant trichomonas vaginalis.
Medical Diagnostic Laboratories, Llc
A method for predicting a subject's response to a tusc2 therapy is provided. In particular, a subject's response is predicted based on the proportion of cancers cells that are apoptotic.
Board Of Regents, The University Of Texas System
Automated synthesis device to produce re-188-liposome and method thereof
An automated synthesis device to produce re-188-bmeda solution including: a plurality of reagent vials, three-way solenoid valves, gel filtration columns and micro pumps, and a reaction vial, a product vial, a temporary storage vial, a filter membrane, and a waste vial, wherein the plurality of reagent vials include first reagent vial and second reagent vials being connected to the reaction vial through first micro pump, the third reagent vial and fourth reagent vial being connected to the reaction vial through second micro pump, fifth reagent vial being connected to the reaction vial through third micro pump, and sixth reagent vial being connected to the temporary storage vial through fourth micro pump, wherein the reaction vial is connected to the plurality of gel filtration columns through the micro-pump, respectively. The automated synthesis device is operable with program to upgrade yield and avoid contamination..
Reagent vessel and kit thereof
The present invention is related to a reagent vessel, comprising: at least one first tube and at least one second tube, wherein second tube has a section area of the opening greater than one of the bottom. A kit for a reagent vessel is also provided herein, comprising: the reagent vessel and a stirrer jacket, wherein the section area ratio value for the bottom of the second tube to the stirrer jacket is 1.1 to 3.5.
Taiwan Advanced Nanotech Inc.
An automatic analyzer includes a sample dispensing unit that dispenses a sample into a reaction vessel, a reagent dispensing unit that dispenses a reagent, a sample nozzle cleaning tank that cleans a nozzle of the sample dispensing unit, a reagent nozzle cleaning tank that cleans a nozzle of the reagent dispensing unit, a compressor that supplies compressed air, and cleaning water supply means that supplies cleaning water. The tanks each have an upper vent that allows a nozzle to have access for cleaning, a lower vent that drains the cleaning water, a cleaning water jet port that sprays the cleaning water to the nozzle, and a compressed air jet port that removes residual cleaning water left on the nozzle.
Hitachi High-technologies Corporation