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Proteins

Proteins-related patent applications - as published by the U.S. Patent and Trademark Office (USPTO).


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Mass spectrometry analysis of biomolecules by multiple charge state selection using a concurrent precursor isolation ...
Thermo Finnigan Llc
December 07, 2017 - N°20170352529

A method is described for the analysis of biological polymers, for example, intact proteins or oligonucleotides, by mass spectrometry. This method produces sample ions from a sample containing biological polymers, and ion species are selected that correspond to different charge states of a biological polymer molecule. The ion species are concurrently isolated from the sample ions to generate precursor ions ...
Mass spectrometry-cleavable cross-linker
The Regents Of The University Of California
December 07, 2017 - N°20170350901

Provided herein is synthesis of a novel acidic acid residue targeting sulfoxide-containing ms-cleavable homobifunctional cross-linker. The novel mass spectrometry-cleavable cross-linking agents can be used in mass spectrometry to facilitate structural analysis of intra-protein interactions in proteins and inter-protein interactions in protein complexes. Also disclosed herein are data based on the novel ms-cleavable homobifunctional cross-linker that are complimentary to amine-reactive sulfoxide-containing ...
Pharmaceuticals and methods for treating hypoxia and screening methods therefor
Dana Farber Cancer Institute, Inc.
December 07, 2017 - N°20170350891

Light-generating fusion proteins having a ligand binding site and a light-generating polypeptide moiety and their use as diagnostics, in drug screening and discovery, and as therapeutics, are disclosed. The light-generating fusion protein has a feature where the bioluminescence of the polypeptide moiety changes upon binding of a ligand at the ligand binding site. The ligand may be, for example, an ...
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Proteins Patent Applications
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  • 271+ full patent PDF documents of Proteins-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
Attachment of proteins to interfaces for use in nonlinear optical detection
Biodesy, Inc.
December 07, 2017 - N°20170350883

Methods are disclosed for tethering a biological entity to a substrate comprising: (a) forming a supported lipid bilayer on a surface of a substrate, wherein the supported lipid bilayer comprises an anchor molecule conjugated to a first affinity tag that is present in the lipid bilayer at a concentration greater than or equal to 5 mole percent; and (b) contacting the ...
Long term hematopoietic stem cell specific reporter mouse and uses thereof
The Board Of Trustees Of The Leland Stanford Junior University
December 07, 2017 - N°20170350879

Hoxb5 identifies long-term hematopoietic stem cells. Expression of hoxb5 distinguishes between lt-hscs and non-lt-hscs, and the marker identifies substantially all lt-hsc in the bone marrow. By utilizing fluorescent proteins under the endogenous expression control of hoxb5, lt-hsc can be monitored and isolated, including without limitation detection and monitoring of hsc in bone morrow; production of lt-hsc from pluripotent stem cells ...
Methods of diagnosing chronic obstructive pulmonary disease (copd) using novel molecular biomarkers
Transgenion-international Institute For Regenerative Translational Medicene Gmbh
December 07, 2017 - N°20170349947

The present invention relates to in vitro methods for the diagnosis of chronic obstructive pulmonary disease (copd), wherein the expression of the marker gene tmsb15a is determined. In particular, the invention relates to an in vitro diagnostic method of assessing the susceptibility of a subject to develop progressive copd involving the appearance of irreversible lung damage, wherein the expression ...
Proteins Patent Pack
Download 271+ patent application PDFs
Proteins Patent Applications
Download 271+ Proteins-related PDFs
For professional research & prior art discovery
inventor
  • 271+ full patent PDF documents of Proteins-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
Using programmable dna binding proteins to enhance targeted genome modification
Sigma-aldrich Co., Llc
December 07, 2017 - N°20170349913

Compositions and methods for using programmable dna binding proteins to increase the efficiency and/or specificity of targeted genome modification or to facilitate the detection of specific genomic loci in eukaryotic cells.
Universal platform for genetic code expansion
Trustees Of Boston College
December 07, 2017 - N°20170349891

Methods and compositions are described for selecting and identifying orthogonal aminoacyl synthetase-trna pairs and their use to incorporate unnatural amino acids in a site-specific manner in proteins. Specifically described is a novel e. Coli tyrptophanyl synthetase-trna pair that functions as both an opal and amber suppressor and that incorporates tryptophan analogs into proteins.
Organ mimic device with microchannels and methods of use and manufacturing thereof
Children's Medical Center Corporation
December 07, 2017 - N°20170349871

System and method includes a body having a central microchannel separated by one or more porous membranes. The membranes are configured to divide the central microchannel into a two or more parallel central microchannels, wherein one or more first fluids are applied through the first central microchannel and one or more second fluids are applied through the second or more ...
Modified glycoproteins
Momenta Pharmaceuticals, Inc.
December 07, 2017 - N°20170349662

Modified glycoproteins, and methods of making and using such modified glycoproteins, are described.
Compositions and methods of treating disease with fgfr fusion proteins
Five Prime Therapeutics, Inc.
December 07, 2017 - N°20170349643

The invention provides fgfr fusion proteins, methods of making them, and methods of using them to treat proliferative disorders, including cancers and disorders of angiogenesis. The fgfr fusion molecules can be made in cho cells and may comprise deletion mutations in the extracellular domains of the fgfrs which improve their stability. These fusion proteins inhibit the growth and viability of ...
Compositions and methods for treatment of cytomegalovirus
Variation Biotechnologies Inc.
December 07, 2017 - N°20170349634

The present disclosure provides compositions and methods useful for treating hcmv infection. As described herein, the compositions and methods are based on development of immunogenic compositions that include virus-like particles (vlps) which comprise one or more moloney murine leukemia virus (mmlv) core proteins and include one or more hcmv epitopes, such as, for example, from hcmv envelope glycoproteins gb and/...
Synthesis of cell penetrating peptides for drug delivery and stem cell applications
Temple University-of The Commonwealth System Of Higher Education
December 07, 2017 - N°20170349628

The present invention provides a novel cell penetrating peptide that transports proteins into cells and/or into nuclei and a pharmaceutical containing the peptide.
Proteins Patent Pack
Download 271+ patent application PDFs
Proteins Patent Applications
Download 271+ Proteins-related PDFs
For professional research & prior art discovery
inventor
  • 271+ full patent PDF documents of Proteins-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
In vivo production of proteins
Modernatx, Inc.
December 07, 2017 - N°20170348436

The invention relates to compositions and methods for the preparation, manufacture and therapeutic use of polynucleotides, primary transcripts and mmrna molecules.
Hpv epitopes targeted by t cells infiltrating cervical malignancies for use in vaccines
Academisch Ziekenhuis Leiden H.o.d.n. Lumc
December 07, 2017 - N°20170348410

The present invention relates to novel cd4+ and cd8+ t cell epitopes that are specific for hpv-specific e6 and e7 oncoproteins, to peptides comprising these novel t cell epitopes, and to (vaccine) compositions comprising these peptides for use in methods for the prevention and/or treatment of hpv related diseases. Preferred epitopes are recognized by a t cell that infiltrates ...
Staphylococcus aureus proteins and nucleic acids
Glaxosmithkline Biologicals, Sa
December 07, 2017 - N°20170348407

The invention provides proteins from staphylococcus aureus including amino acid sequences and the corresponding nucleotide sequences. The proteins are useful for vaccines, immunogenic compositions, diagnostics, enzymatic studies and also as targets for antibiotics.
Anthelmintic probiotic compositions and methods
University Of Massachusetts
December 07, 2017 - N°20170348362

Compositions and methods for treating or reducing the severity or likelihood of occurrence of a parasitic worm or helminth infection in a subject are described. The methods include administering to the subject a therapeutically effective amount of a recombinant bacterium expressing a crystal protein such as a bacillus thuringiensis crystal protein (cry). The crystal proteins may be full length, truncated, ...
Products containing charged polymer complex microcapsules and method of use
Capsulent
December 07, 2017 - N°20170348204

A microcapsule suspension for treating a protein-containing surface includes droplets of a dispersed water-immiscible core phase, an aqueous continuous phase, and a wall surrounding each core phase droplet. The wall includes the salt formed from at least one lewis base reactant and at least one lewis acid reactant, wherein at least one lewis base reactant or lewis acid reactant is ...
Composition comprising a mixture of proteins
Compagnie Gervais Danone
December 07, 2017 - N°20170347679

The invention relates to compositions comprising a mixture of proteins, with a high amount of whey protein. The proteins further comprise a casein compound. The resulted compositions have a good processability and texture.
Whey protein concentrate, acidified milk products comprising the concentrate and methods therefor
Valio Ltd
December 07, 2017 - N°20170347673

The present invention relates to a method of producing an ideal whey protein concentrate. The whey protein concentrate has a ph in the range of 6. 8-7. 5 and 70-90% of the total proteins of the concentrate are whey proteins and 10-30% of the total proteins of the concentrate are caseins. The present invention relates also to an ideal whey protein concentrate ...
Fusion proteins, recombinant bacteria, and exosporium fragments for animal health and aquaculture
Spogen Biotech Inc.
December 07, 2017 - N°20170347664

Fusion proteins, recombinant bacillus cereus family members that express fusion proteins, and exosporium fragments derived from spores of the recombinant bacillus cereus family members are provided. Compositions comprising the spores or exosporium fragments are also provided. Methods involving the use of spores of recombinant bacillus cereus family members and exosporium fragments derived from spores of a recombinant bacillus cereus family ...
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