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Proteins

Proteins-related patent applications - as published by the U.S. Patent and Trademark Office (USPTO).


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Mycobacterium tuberculosis proteins
Oxford Immunotec Limited
August 17, 2017 - N°20170234871

The present invention relates to mycobacterium tuberculosis (m tuberculosis) proteins and immunologically active fragments (peptides or mimotope peptides) thereof. In particular, the invention relates to a group of m. Tuberculosis proteins and peptides thereof that are both highly antigenic and characteristic of clinical strains of m. Tuberculosis. Accordingly, the further relates to the use of these m. Tuberculosis proteins or ...
Biosensor based on g-beta-gamma-interacting proteins to monitor g-protein activation
UniversitÉ De MontrÉal
August 17, 2017 - N°20170234870

Resonance energy transfer (ret)- or protein-fragment complement assay (pca)-based biosensors useful for assessing the activity of g-proteins are described. These biosensors are based on the competition between the got subunit and a gβγ interacting protein (βγ ip) for the binding to the gβγ dimer. These biosensors comprises (1) ...
Anti-carbamylated protein antibodies and the risk for arthritis
Academisch Ziekenhuis Leiden H.o.d.n. Lumc
August 17, 2017 - N°20170234869

Antibodies against citrullinated protein antigens (acpa) have shown their relevance for the diagnosis and possibly pathogenesis in arthritis. Described are means and methods for determining antibodies against homocitrulline-containing proteins or carbamylated proteins/peptides (anti-carp) for the classification of individuals suffering from, or at risk of suffering from, arthritis.
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Proteins Patent Applications
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Method for making a biofabricated material containing collagen fibrils
Modern Meadow, Inc
August 17, 2017 - N°20170233834

Described herein is a method for producing a biofabricated material from collagen or collagen-like proteins which are recombinantly produced and which contain substantially no 3-hydroxyproline. The collagen or collagen-like proteins are isolated from animal sources, or produced by recombinant dna techniques or by chemical synthesis. The collagen or collagen-like proteins are fibrillated, crosslinked, dehydrated and lubricated thus forming the biofabricated ...
Dna array for detecting canine toll-like receptor gene mutations
Crag-centre De Recerca En Agrigenòmica
August 17, 2017 - N°20170233811

Dna array for detecting canine toll-like receptor gene mutations new mutations in canine toll-like receptor genes are provided. The invention relates further to dna arrays comprising oligonucleotides capable of hybridizing to at least a tlr gene fragment codifying for at least one of the new mutations leading to non-functional proteins. The invention also includes methods for the analysis of mutations ...
Cysteine labelling
University Of Dundee
August 17, 2017 - N°20170233788

The present invention relates to the production of activated biological molecules for use in profiling biological molecule interactions. The activated biological molecule may be a ubiquitin (ub) and ubiquitin-like conjugation enzyme as well as other proteins with internal reactive cysteine residues.
Proteins Patent Pack
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Proteins Patent Applications
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inventor
  • 271+ full patent PDF documents of Proteins-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
Non-disruptive gene targeting
Board Of Regents Of The University Of Texas System
August 17, 2017 - N°20170233765

Compositions and methods are provided for integrating one or more genes of interest into cellular dna without substantially disrupting the expression of the gene at the locus of integration, i. E., the target locus. These compositions and methods are useful in any in vitro or in vivo application in which it is desirable to express a gene of interest in ...
Insecticidal polypeptides having broad spectrum activity and uses thereof
Pioneer Hi-bred International, Inc.
August 17, 2017 - N°20170233759

The invention provides nucleic acids, and variants and fragments thereof, obtained from strains of bacillus thuringiensis encoding polypeptides having pesticidal activity against insect pests, including lepidoptera and coleoptera. Particular embodiments of the invention provide isolated nucleic acids encoding pesticidal proteins, pesticidal compositions, dna constructs, and transformed microorganisms and plants comprising a nucleic acid of the embodiments. These compositions find use ...
Herbicide tolerant triple gene insecticidal cotton and other plants
Pioneer Hi-bred International, Inc.
August 17, 2017 - N°20170233758

The present invention refers to the next-generation three genes cotton (gossypium hirsutum) expressing chloroplast-targeted herbicide tolerant gene resistant to broad and narrow-leaved weedicide sprays and two b. Thuringiensis insecticidal genes δ-endotoxin cry2a and vegetative insecticidal protein gene vip3a. Both cry2a and vip3a genes have different modes of action in controlling a wide spectrum of ...
Site-specific incorporation of phosphoserine into proteins in escherichia coli
Yale University
August 17, 2017 - N°20170233749

Nucleic acids encoding mutant elongation factor proteins (ef-sep), phosphoseryl-trna synthetase (seprs), and phosphoseryl-trna (trnasep) and methods of use in site specific incorporation of phosphoserine into a protein or polypeptide are described. Typically, seprs preferentially aminoacrylates trnasep with o-phosphoserine and the trnasep recognizes at least one codon such as a stop codon. Due to the negative charge of the phosphoserine, sep-trnasep ...
Targeted/immunomodulatory fusion proteins and methods for making same
Biocon Limited
August 17, 2017 - N°20170233747

The present invention relates generally to the field of generating fusion proteins to be used in cancer therapy, and more specifically, to nucleotide sequences encoding the fusion proteins, wherein the chimeric fusion proteins comprises at least one targeting moiety and at least one immunomodulatory moiety that counteracts the immune tolerance of cancer cells.
Compositions and methods for improved protein production
Danisco Us Inc.
August 17, 2017 - N°20170233746

Aspects of the present disclosure are drawn to methods of improving the expression of secreted cuproenzymes from host cells by manipulating the expression level of one or more proteins involved in copper transport in the host cell, e. G., membrane-bound copper transporting atpases and soluble copper transporters. The present disclosure also provides compositions containing such improved host cells as well ...
Evolution of proteases
President And Fellows Of Harvard College
August 17, 2017 - N°20170233708

Some aspects of this disclosure provide methods for phage-assisted continuous evolution (pace) of proteases. Some aspects of this invention provide methods for evaluating and selecting protease inhibitors based on the likelihood of the emergence of resistant proteases as determined by the protease pace methods provided herein. Some aspects of this disclosure provide strategies, methods, and reagents for protease pace, including ...
Proteins Patent Pack
Download 271+ patent application PDFs
Proteins Patent Applications
Download 271+ Proteins-related PDFs
For professional research & prior art discovery
inventor
  • 271+ full patent PDF documents of Proteins-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
Method for making a biofabricated material containing collagen fibrils
Modern Meadow, Inc.
August 17, 2017 - N°20170233536

Described herein is a method for producing a biofabricated material from collagen or collagen-like proteins. The collagen or collagen-like proteins are isolated from animal sources or produced by recombinant dna techniques or by chemical synthesis. The collagen or collagen-like proteins are fibrillated, crosslinked, dehydrated and lubricated thus forming the biofabricated material having a substantially uniform network of collagen fibrils.
Degumming method
Universite De Nantes
August 17, 2017 - N°20170233499

A method for producing membrane polysaccharides from an organism selected from micro-organisms, unicellular organisms and filamentous fungi, the method including at least one step of extracting the membrane polysaccharides as well as a smaller-scale extraction of the soluble proteins, by mechanical treatment of the organism in a ball mill or by physical treatment of the organism by means of ultrasounds.
Heterodimeric antibody fc-containing proteins and methods for production thereof
Genmab A/s
August 17, 2017 - N°20170233497

Novel heterodimeric antibody-fc-containing proteins, such as bispecific antibodies, and novel methods for producing such proteins
Affinity proteins and uses thereof
Nectagen, Inc.
August 17, 2017 - N°20170233496

In general, the invention features a novel cbm32-derived affinity scaffold. In certain embodiments, the scaffold comprises two types of regions: constant regions (crs) and variable loop regions (vlrs) as depicted in the structure in fig. 1. We have discovered that the crs provide structural features that enable overall conformational stability while the intervening sequences corresponding to vlrs tolerate amino acid ...
Antibodies specific for mmp9
Merck Patent Gmbh
August 17, 2017 - N°20170233495

The present invention relates to new proteins that bind to mmp9 and comprise at least one fragment of a heavy chain variable region and/or at least one fragment of a light chain variable region of an antibody. In particular, the mmp9 binding proteins according to the invention are able to neutralize mmp9 activity and are useful in the prevention ...
Method of manufacturing intravenous immunoglobulin from fraction iii
Merck Patent Gmbh
August 17, 2017 - N°20170233458

The present subject matter is directed to a method of manufacturing purified ivig from fraction iii of plasma, comprising re-constituting a fraction iii paste in a buffer; adjusting the ph and temperature; adding ethanol and then gradually lowering the temperature; centrifuging and filtering the supernatant; ultra-filtrating to remove alcohol; undergoing weak anion exchange chromatography; ultra-filtrating to reach a desired protein ...
An improved expression cassette for packaging and expression of variant factor viii for the treatment ...
The Children's Hospital Of Philadelphia
August 17, 2017 - N°20170233456

Factor viii variants and methods of use thereof are disclosed. In particular embodiments, factor viii variants are expressed more efficiently by cells over wild-type factor viii proteins, are secreted at increased levels by cells over wild-type factor viii proteins, exhibit enhanced activity over wild-type factor viii proteins and are packaged more efficiently into viral vectors.
Interleukin-2/interleukin-2 receptor alpha fusion proteins and methods of use
University Of Miami
August 17, 2017 - N°20170233448

Various methods and compositions are provided which can be employed to modulate the immune system. Compositions include a fusion protein comprising: (a) a first polypeptide comprising interleukin-2 (il-2) or a functional variant or fragment thereof; and (b) a second polypeptide, fused in frame to the first polypeptide, wherein the second polypeptide comprises an extracellular domain of interleukin-2 receptor alpha (il-2...
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