Popular terms

Proliferation topics
Proliferation
Cell Proliferation
Differentiation
Cancer Cell
Antibodies
Progesterone
Specificity
Cancer Cells
Antimicrobial
Lymphocyte
Cell Differentiation
Homogeneous
Amino Acids
Wound Healing
Epithelial

Follow us on Twitter
twitter icon@FreshPatents

Web & Computing
Cloud Computing
Ecommerce
Search patents
Smartphone patents
Social Media patents
Video patents
Website patents
Web Server
Android patents
Copyright patents
Database patents
Programming patents
Wearable Computing
Webcam patents

Web Companies
Apple patents
Google patents
Adobe patents
Ebay patents
Oracle patents
Yahoo patents

[SEARCH]

Proliferation patents



      

This page is updated frequently with new Proliferation-related patent applications.




Date/App# patent app List of recent Proliferation-related patents
06/16/16
20160169863 
 Means and methods for assessing increased peroxisomal proliferation patent thumbnailMeans and methods for assessing increased peroxisomal proliferation
The present invention pertains to the field of toxicological assessments for risk stratification of chemical compounds. Specifically, it relates to a method for diagnosing increased peroxisomal proliferation.
Basf Se


06/16/16
20160168205 
 Methods and compositions for labeling polypeptides patent thumbnailMethods and compositions for labeling polypeptides
Synthesis of many proteins is tightly controlled at the level of translation and plays an essential role in fundamental processes such as cell growth and proliferation, signaling, differentiation or death. Methods that allow imaging and identification of nascent proteins allow for dissecting regulation of translation, both spatially and temporally, including in whole organisms.
President And Fellows Of Harvard College


06/16/16
20160166652 
 Novel n- and c-terminal substituted antagonistic analogs of gh-rh patent thumbnailNovel n- and c-terminal substituted antagonistic analogs of gh-rh
There is provided a novel series of synthetic analogs of hgh-rh(1-29)nh2 (seq id no: 1) and hgh-rh(1-30)nh2. Of particular interest are those carrying phac, n-me-aib, dca, ac-ada, fer, ac-amc, me-nh-sub, phac-ada, ac-ada-d-phe, ac-ada-phe, dca-ada, dca-amc, nac-ada, ada-ada, or ch3—(ch2)10—co-ada, at the n-terminus and β-ala, amc, apa, ada, ae2a, ae4p, ε-lys(α-nh2), agm, lys(oct) or ahx, at the c-terminus.
U.s.a., Represented By The Department Of Veterans Affairs


06/16/16
20160166536 
 Combination therapy for the treatment of cancer patent thumbnailCombination therapy for the treatment of cancer
Pharmaceutical compositions and methods of inhibiting tumor cell proliferation of triple-negative (er−/pr−/her2−) breast cancer cells and for treating subjects with a form of breast cancer having a triple-negative (er−/pr−/her2−) phenotype are provided. The methods include a step of contacting triple-negative breast cancer cells with an effective amount of a composition including eribulin and cyc065..
Northwestern University


06/09/16
20160159919 
 Therapeutic agent comprising humanized anti-epiregulin antibody as active ingredient for non-small-cell lung carcinoma excluding adenocarcinoma patent thumbnailTherapeutic agent comprising humanized anti-epiregulin antibody as active ingredient for non-small-cell lung carcinoma excluding adenocarcinoma
The present inventors successfully produced therapeutic agents for non-small cell lung cancer except adenocarcinoma, comprising as active ingredient an anti-epiregulin antibody that shows cross-species reactivity between the human animal and cynomolgus which is a non-human animal, an anti-epiregulin antibody with suppressed chemical degradation, an anti-epiregulin antibody with reduced isoelectric point, an anti-epiregulin antibody with increased midpoint temperature of thermal denaturation, or an anti-epiregulin antibody with reduced amount of aggregates, generated by appropriately substituting amino acid residues in the variable-region sequences of a humanized ep27 antibody that inhibits cancer cell proliferation by exerting a cytotoxicity and a neutralizing activity against human epiregulin-expressing cancer cells.. .
Miyagi Cancer Center Research Institute


06/09/16
20160159872 
 Methods and compositions for treating cancer and inflammatory diseases patent thumbnailMethods and compositions for treating cancer and inflammatory diseases
The invention provides a peptide construct comprising a cell penetrating peptide and an inhibitory peptide that interferes with the interaction between e1a and ctbp. The invention also provides related pharmaceutical composition comprising such a peptide construct.
The Regents Of The University Of Colorado, A Body Corporate


06/09/16
20160159861 
 Apj receptor compounds patent thumbnailApj receptor compounds
The invention relates generally to compounds which are allosteric modulators (e.g., negative and positive allosteric modulators, allosteric agonists, and ago-allosteric modulators) of the g protein coupled receptor apelin, also known as the apj receptor. The apj receptor compounds are derived from the it intracellular loop and domain of the apj receptor.
Anchor Therapeutics, Inc.


06/09/16
20160159843 
 Nucleoside and nucleotide derivatives patent thumbnailNucleoside and nucleotide derivatives
Which inhibit, preventing or treating abnormal cellular proliferation and/or a viral infection, particularly by hiv, hcv or hbv. Consequently, the compounds of the present invention interfere with the replication cycle of a virus and are also useful as antiviral agents, or interfere with host cellular biochemical process and are also useful as antiproliferative agents.

06/09/16
20160158414 
 Anisotropic constructs and methods for forming and using same for treating damaged biological tissue patent thumbnailAnisotropic constructs and methods for forming and using same for treating damaged biological tissue
Anisotropic constructs having a base member with a defined surface that includes a plurality of substantially parallel equidistant linear channels that are configured to modulate the polarity and proliferation of cells through spatial and biomechanical cues. The constructs are also capable of administering a biologically active agent and/or a pharmacological composition to tissue..
Cormatrix Cardiovascular, Inc.


06/09/16
20160158244 
 Pharmaceutical compositions for the treatment of cancer and other diseases or disorders patent thumbnailPharmaceutical compositions for the treatment of cancer and other diseases or disorders
Or a pharmaceutically acceptable salt thereof, that are suitable for the bulk production of an oral pharmaceutical dosage form; processes for the production of said oral pharmaceutical dosage form; and the use of the pharmaceutical composition for the treatment of patients suffering from or subject to diseases, disorders, or conditions involving cell survival, proliferation and migration, including chronic inflammatory proliferative disorders, proliferative ocular disorders, benign proliferative disorders, and cancer.. .

06/09/16
20160158163 

Method for treating gefitinib-resistant non-small-cell lung cancer


The present invention relates to a method for treating gefitinib-resistant non-small-cell lung cancer (nsclc) comprising administering an effective amount of a resveratrol analogue, (z)3,4,5,4′-tetramethoxystilbene (tms), to a subject in need thereof. The present invention also relates to a method for inducing apoptosis in gefitinib-resistant nsclc cells comprising contacting the resveratrol analogue to the cells at an effective amount.
Macau University Of Science And Technology


06/02/16
20160152582 

Therapeutic compounds


Or salts thereof are provided. Pharmaceutical compositions comprising a compound of formula i′, processes for preparing compounds of formula i′, intermediates useful for preparing compounds of formula i′ and therapeutic methods for treating the proliferation of the hiv virus, treating aids or delaying the onset of aids or arc symptoms in a mammal are also provided..

06/02/16
20160151460 

Method of treating skeletal dysplasias using vessel dilator


C-natriuretic peptide (cnp) has been shown to regulate proliferation of mouse and rat osteoblasts. Genetic deletion of cnp results in dwarfism.
United States Department Of Veterans Affairs


06/02/16
20160151430 

Composition for inducing proliferation or accumulation of regulatory t cells


It was found that bacteria belonging to the genus clostridium induce accumulation of regulatory t cells (treg cells) in the colon. Moreover, the present inventors found that regulatory t cells (treg cells) induced by from these bacteria suppressed proliferation of effector t-cells.
The University Of Tokyo


06/02/16
20160151424 

Amniotic membrane preparations and purified compositions and anti-inflammation methods


Compositions having a combination of specific biological components have been found to exert a number of useful effects in mammalian cells, including modulating tgf β signaling, apoptosis, and proliferation of mammalian cells, as well as decreasing inflammation in mice. These components can be obtained commercially, or can be prepared from biological tissues such as placental tissues.
Tissuetech, Inc.


06/02/16
20160151406 

Combination cancer therapy with c-met inhibitors and synthetic oligonucleotides


Methods of inhibiting, and preventing the proliferation of, cancer cells, as well as treating cancer in an individual (e.g., a liver cancer, for example hepatocellular carcinoma) can include providing both a synthetic mir-34 family molecule and a c-met inhibitor (e.g., tivantinib) to an individual in need thereof. The combination of the synthetic mirna molecule and c-met inhibitor can provide a desirable or superior effect, for example a more efficacious treatment than an alternative therapy, or the synthetic mirna molecule or c-met inhibitor alone.
Mirna Therapeutics, Inc.


06/02/16
20160151315 

S isomers of alpha-methyl-hydrocinnamic acid for the treatment of blood disorders


The present intervention generally relates to compositions comprising s-isomer of alpha-methyl-hydrocinnamic acid for the treatment and/or prevention of blood disorders and blood deficiencies, as well as methods for treating blood disorders and/or blood deficiency in a subject by administering a composition comprising s-isomer of alpha-methyl-hydrocinnamic acid to the subject to ameliorate at least one symptom associated with the blood disorder. Another aspect relates to administration of an s-isomer of alpha-methyl-hydrocinnamic acid stimulate multi-lineage hematopoietic cell production in a subject, for example, increasing the numbers of circulating neutrophils, erythrocytes and platelets.

06/02/16
20160151312 

Polyamine transport inhibitors as novel therapeutics


Novel polyamine transport inhibitors have been synthesized and demonstrated to block the uptake of native polyamines into human cancer cells. A combination therapy of the transport inhibitor and dfmo (a drug which blocks polyamine biosynthesis) provided synergistic activity against a metastatic human colon cancer cell line.
University Of Central Florida Research Foundation, Inc.


06/02/16
20160150774 

Device for sealing stagnant water tanks


A device for combating the proliferation of aquatic larvae in containers likely to hold stagnant water, the containers (1) including a wall (2) defining a cavity (3) and an open hole (4), and including an element (10) whose shape is designed to completely or partially conform to that of the wall (2) of the cavity and to seal the hole, the element being produced from a porous material permeable to air and to water, including a rubber granulate and a synthetic binder. The device made from porous material occupies the opening of the tank which can therefore no longer be freely accessed by mosquitoes.

05/26/16
20160145628 

Nanocarrier system for micrornas and uses thereof


Described herein are novel polyglycerol-amine polymeric nanocarriers in complex with micrornas and their uses in the treatment of cancer, in particular glioblastoma. Delivery of the polymeric nanocarriers in complex with micrornas in cell lines and in vivo inhibited cell proliferation, cell cycle progression, cell migration and tumor growth..
Rosetta Genomics Ltd.


05/26/16
20160145622 

Dengue virus-specific sirna, double helix oligo-rna structure comprising sirna, and composition for suppressing proliferation of dengue virus comprising rna structure


The present invention relates to a dengue virus-specific sirna, a double-stranded oligo rna structure comprising the sirna, and a composition for inhibiting dengue virus replication, which comprises the same, in which the double-stranded oligo rna structure comprises a hydrophilic compound and hydrophobic compound conjugated to both ends of the double-stranded rna (sirna) by a single covalent bond or a linker-mediated covalent bond so that they will be efficiently delivered into cells, and can be converted into nanoparticles by hydrophobic interactions between the double-stranded oligo rna structures in an aqueous solution. The sirna included in the double-stranded oligo rna structure acts specifically on all dengue virus serotypes.
Bioneer Corporation


05/26/16
20160145618 

Albumin production and cell proliferation


The present invention provides short activating rna molecules which up-regulate albumin production. The present invention also provides methods of up-regulating albumin production, such methods involving the use of short activating rna molecules capable of increasing the expression of albumin.
Mina Therapeutics Limited


05/26/16
20160145352 

Camelid single heavy-chain antibody directed against chromatin and uses of same


Disclosed is a polypeptide including a single-domain antibody directed against chromatin, derived from a heavy-chain antibody devoid of a camelid light chain (vhh) and capable of binding specifically with a complex of h2a and h2b histones. This polypeptide is particularly suitable for detecting/viewing chromatin in real time, without interfering with the rate of cell proliferation..
Universite Paul Sabatier Toulouse Iii


05/26/16
20160145302 

A short peptide targeting eps8 binding with egfr and use thereof


The present invention discloses a short peptide targeting eps8 binding with egfr and use thereof, and sequence of the short peptide is n′-arg-lys-lys-asn-lys-pro-pro-pro-pro-lys-lys-c′. The short peptide can effectively inhibit proliferation of eps8 positive tumors, and can also be used to make a pharmaceutical preparation for treating eps8 positive tumors, which has the potential of being developed into anti-cancer peptide inhibitor drugs..
Southern Medical University


05/26/16
20160144056 

Materials and methods for the treatment of pathological neovascularization in the eye


The subject invention provides materials and methods useful in safely and effectively preventing pathological proliferation of blood vessels. The prevention of the over-proliferation of blood vessels according to the subject invention is particularly advantageous for treatment of certain ocular conditions including age-related macular degeneration (amd), retinopathy of prematurity (rop) and diabetic retinopathy.
Florida Atlantic University Research Corporation


05/26/16
20160143969 

Gene-modified coxsackievirus


A modified coxsackievirus showing improved safety and/or aggressiveness to be used for oncolytic virotherapy is provided. A modified coxsackievirus showing tissue-specific suppression of proliferation and comprising a imitated genome consisting of the genome of coxsackievirus b3 wild-type (cvb3-wt) inserted with at least one polynucleotide consisting of a target sequence of tissue-specific micror na (mirna) is provided.
Kyushu University National University Corporation


05/26/16
20160143960 

Composition for inducing proliferation or accumulation of regulatory t cells


It was found that bacteria belonging to the genus clostridium induce accumulation of regulatory t cells (treg cells) in the colon. Moreover, the present inventors found that regulatory t cells (treg cells) induced by from these bacteria suppressed proliferation of effector t-cells.
The University Of Tokyo


05/26/16
20160143950 

Stem cells and stem cell factors for inhibiting the progression of alzheimer's disease


Therapeutic stem cells and methods for their use and manufacture. Stem cells are produced under conditions in which the stem cells are exposed to at least one environmental factor, including decreased oxygen tension.

05/26/16
20160143267 

Maintenance medium for primate pluripotent stem cells


Provided are a maintenance medium for primate pluripotent stem cells, and a method for preserving and a method for controlling proliferation of primate pluripotent stem cells using the medium. The maintenance medium for human pluripotent stem cells according to the present invention includes xylose as a saccharide..
Bourbon Corporation


05/19/16
20160138027 

Treatment of diseases and conditions associated with dysregulation of mammalian target of rapamycin complex 1 (mtorc1)


Compositions and methods for treating diseases and conditions associated with dysregulation of mammalian target of rapamycin complex 1 (mtorc1) are disclosed. The invention is based in part on the discovery that protein mediator of amino acid signaling to mtor (mortor) is involved in amino acid-induced translocation of mtorc1 to lysosomes where mortor forms a signaling complex with mtorc1, ragulator, and rag gtpases, which controls protein synthesis.
The Board Of Trustees Of The Leland Stanford Junior University


05/19/16
20160137585 

Compositions and methods for glucose transport inhibition


Glucose deprivation is an attractive strategy in cancer research and treatment. Cancer cells upregulate glucose uptake and metabolism for maintaining accelerated growth and proliferation rates.
Ohio University


05/19/16
20160136273 

Compositions including triciribine and trastuzumab and methods of use thereof


This application relates to combination therapies including triciribine and related compounds and trastuzumab or a salt thereof and compositions with reduced toxicity for the treatment and prevention of tumors, cancer, and other disorders associated with abnormal cell proliferation.. .
University Of South Florida


05/19/16
20160136248 

Methods and materials for modulating deubiquitinases and ubiquitinated polypeptides


This document relates to methods and materials involved in modulating deubiquitinases (e.g., usp10 polypeptides) and/or ubiquitinated polypeptides (e.g., tumor suppressor polypeptides or mutant versions of tumor suppressor polypeptides). For example, methods and materials for increasing deubiquitinase (e.g., a usp10 polypeptide) expression or activity, methods and materials for decreasing deubiquitinase (e.g., a usp10 polypeptide) expression or activity, methods and materials for stabilizing tumor suppressor polypeptides (e.g., wild-type p53 polypeptides), methods and materials for de-stabilizing mutant versions of tumor suppressor polypeptides (e.g., mutant p53 polypeptides), and methods and materials for reducing cancer cell proliferation, increasing cancer cell apoptosis, and/or treating cancer (e.g., cancers having reduced levels of wild-type p53 polypeptides or cancers having increased levels of mutant p53 polypeptides) are provided.
Mayo Foundation For Medical Education And Research


05/19/16
20160136234 

Compositions and methods for preventing or treating diseases, conditions, or processes characterized by aberrant fibroblast proliferation and extracellular matrix deposition


The described invention provides compositions and methods for reducing progression of a fibrosis in a tissue of a subject selected from liver, kidney or vascular fibrosis, the progression of the fibrosis being characterized by aberrant fibroblast proliferation and extracellular matrix deposition in the tissue. The method includes administering a therapeutic amount of a pharmaceutical composition containing a polypeptide having the amino acid sequence yaraaarqarakalarqlgvaa (seq id no: 1) or functional equivalent thereof, and a pharmaceutically acceptable carrier, wherein the therapeutic amount of the polypeptide is effective to reduce progression of the fibrosis, to treat remodeling of the tissue, or a combination thereof..
Moerae Matrix, Inc.


05/19/16
20160136228 

Compositions including triciribine and bortezomib and derivatives thereof and methods of use thereof


This application relates to combination therapies including triciribine and related compounds and bortezomib and derivatives thereof analogs and compositions with reduced toxicity for the treatment and prevention of tumors, cancer, and other disorders associated with abnormal cell proliferation.. .
University Of South Florida


05/19/16
20160136164 

Methods and compositions for the treatment of cancer and related hyperproliferative disorders


The present invention relates to methods of treating a disease related to cell hyper-proliferation via administration of a therapeutically effective amount of a compound having a general tripartite structure a-b—c. In the tripartite structure a, b, and c are identical or non-identical structures, for example, but not limited to, heterocyclic, phenyl or benzyl ring structures with or without substitutions and are described in detail herein.
Baylor College Of Medicine


05/12/16
20160130637 

Dual labeling methods for measuring cellular proliferation


The present invention provides a method for measuring cellular nascent nucleic acid synthesis by dual pulse labeling of nucleic acid. The first pulse labeling of nucleic acid with a nucleoside analog allows establishment of a baseline nucleic acid synthesis rate.
Life Technologies Corporation


05/12/16
20160130269 

7-azaindole derivatives


Compounds of the formula (i) in which r, r1, r2 and r3 have the meanings indicated in claim 1, are inhibitors of pdk1 and cell proliferation/cell vitality and can be employed for the treatment of tumors.. .
Merck Patent Gmbh


05/12/16
20160129109 

Universal anti-tag chimeric antigen receptor-expressing t cells and methods of treating cancer


The present invention provides a universal, yet adaptable, anti-tag chimeric antigen receptor (at-car) system which provides t cells with the ability and specificity to recognize and kill target cells, such as tumor cells, that have been marked by tagged antibodies. As an example, αfitc-car-expressing t cells have been developed that specifically recognize various human cancer cells when those cells are bound by cancer-reactive fitc-labeled antibodies.
University Of Maryland, Baltimore


05/12/16
20160129069 

Method for inducing proliferation of dopaminergic cells


A method for inducing a proliferation of dopaminergic cells in a subject in need, comprising: administering a herbal medicinal composition to a subject in need, wherein the herbal medicinal composition comprises: ginseng radix, glycyrrhiza uralensis, zingiber officinale roscoe, cinnamomum cassia presl., and scutellariae radix.. .

05/12/16
20160129068 

Composition of plant extract and its pharmaceutical composition and application thereof


The present invention is related to a composition for relieving joint inflammation. The present invention is also related to a method for treatment of joint inflammation, comprising a step of administering to a subject in need thereof a therapeutically effective amount of a pharmaceutical composition.
Caliway Biomedical Co., Ltd.


05/12/16
20160129051 

Amniotic membrane preparations and purified compositions and anti-angiogenesis treatment


Compositions having a combination of specific biological components have been found to exert a number of useful effects in mammalian cells, including modulating tgf β signaling, apoptosis, and proliferation of mammalian cells, as well as decreasing inflammation in mice. These components can be obtained commercially, or can be prepared from biological tissues such as placental tissues.
Tissuetech, Inc.


05/12/16
20160129050 

Amniotic membrane preparations and purified compositions and therapy for scar reversal and inhibition


Compositions having a combination of specific biological components have been found to exert a number of useful effects in mammalian cells, including modulating tgf β signaling, apoptosis, and proliferation of mammalian cells, as well as decreasing inflammation in mice. These components can be obtained commercially, or can be prepared from biological tissues such as placental tissues.
Tissuetech, Inc.


05/12/16
20160129049 

Purified amniotic membrane compositions and methods of use


Compositions having a combination of specific biological components have been found to exert a number of useful effects in mammalian cells, including modulating tgf β signaling, apoptosis, and proliferation of mammalian cells, as well as decreasing inflammation in mice. These components can be obtained commercially, or can be prepared from biological tissues such as placental tissues.
Tissuetech, Inc.


05/12/16
20160129047 

Conditioned medium from human adult liver stem cells and its use in the treatment of liver disorders


The invention relates to cell-free compositions obtained by culturing adult-derived human liver stem/progenitor cells (adhlsc) in cell culture medium and isolating the resulting conditioned medium (adhlsc-cm) that has advantageous property ties, such as anti-fibrotic effects. Adhlsc-cm, compositions based on adhlsc-cm, and other related and derived products, can be used in cell culture processes or as a medicament, more particularly for the treatment of diseases involving organ injury, organ failure, in organ or cell transplantation or the pathological disruption, inflammation, degeneration, and/or proliferation of cells within a tissue or an organ, in particular within liver..
UniversitÉ Catholique De Louvain


05/12/16
20160129032 

Receptor-type kinase modulators and methods of use


The present invention provides compounds for modulating receptor kinase activity, particularly ephrin and egfr, and methods of treating diseases mediated by receptor kinase activity utilizing the compounds and pharmaceutical compositions thereof. Diseases mediated by receptor kinase activity include, but are not limited to, diseases characterized in part by abnormal levels of cell proliferation (i.e.
Symphony Evolution, Inc.


05/12/16
20160128991 

Indazole inhibitors of the wnt signal pathway and therapeutic uses thereof


Indazole compounds for treating various diseases and pathologies are disclosed. More particularly, the present invention concerns the use of an indazole compound or analogs thereof, in the treatment of disorders characterized by the activation of wnt pathway signaling (e.g., cancer, abnormal cellular proliferation, angiogenesis, alzheimer's disease and osteoarthritis), the modulation of cellular events mediated by wnt pathway signaling, as well as genetic diseases due to mutations in wnt signaling components.
Samumed, Llc


05/05/16
20160125127 

Identification of minimal combinations of oncoproteins in notch pathway to suppress human glioblastoma


The invention is directed to in-silico method to identify combinatorial oncoprotiens as potential drug targets or combinatorial oncoprotien biomarkers in notch pathway to suppress the human glioblastoma proliferation.. .
Council Of Scientific & Industrial Research


05/05/16
20160122702 

Method for determining cell state and autoanalyzer using said method


There is provided a method for noninvasively evaluating the cell state (proliferation, multi-layering, and differentiation) of a cell sheet as a mimic tissue at the time of culturing the cell sheet. The method is characterized in that an analysis of an amino acid is conducted with the use of the culture supernatant of a cell sheet to monitor a change in the concentration of any amino acid selected from a group of 5-species of amino acids (ile, val, ser, leu, and ala), thereby making a determination..
Hitachi High-technologies Corporation


05/05/16
20160122434 

Antagonist of the btla/hvem interaction for use in therapy


The present invention relates to an antagonist of the btla/hvem interaction for use in therapy, wherein said antagonist increases the proliferation of vγ9vδ2 t cells.. .
Centre National De La Recherche Scientifique-cnrs


05/05/16
20160122426 

Anti-vegf antibody, and pharmaceutical composition for preventing, diagnosing or treating cancer or angiogenesis-related diseases, containing same


A novel anti-vascular endothelial growth factor (vegf) antibody having a strong binding affinity for vegf and capable of inhibiting in vivo tumor growth and a composition for the treatment of cancer, containing the same. The antibody shows a remarkable binding property to human and mouse vegf, suppresses the proliferation and permeability of a human umbilical vein endothelial cell (huvec) and inhibits tumor growth, and thus can be useful as an antibody for the treatment of cancer..
Dong-a St Co., Ltd


05/05/16
20160122402 

Retro polypeptides for activation immunity to cancer and viral infection


A polypeptide that drives t cell proliferation and differentiation, and methods and agents for modulating the expression and/or function of the polypeptide. Agents that up regulate the expression and/or function of the polypeptide are useful in the treatment or prevention of diseases and disorders that would benefit from stimulation of t cell proliferation and/or differentiation, such as cancer and chronic viral infections.
Imperial Innovations Limited


05/05/16
20160122390 

A biomimetic peptide and biodegradable delivery platform for the treatment of angiogenesis- and lymphangiogenesis-dependent diseases


Mimetic peptides having anti-angiogenic and anti-tumorigenic properties and methods of their use for treating cancer, ocular diseases, such as age-related macular degeneration, and other-angiogenesis-dependent diseases are disclosed. More particularly, an isolated peptide comprising the amino acid sequence lrrfstapfafidindvinf, which exhibits anti-angiogenic activity in endothelial cell proliferation, migration, adhesion, and tube formation assays, anti-migratory activity in human breast cancer cells in vitro, anti-angiogenic and anti-tumorigenic activity in vivo in breast cancer xenograft models, and age-related macular degeneration models is disclosed.
The Johns Hopkins University


05/05/16
20160120979 

Method of applying a composition and pharmaceutical composition with a regimen of administering it


A method applying a composition to a human or non-human individual or to an object or a surface area and a pharmaceutical composition with a regimen of administering it to a human or non-human individual is provided. The composition includes an active chemical component for killing of or retarding proliferation of target cells including pathogens, infected cells and cancer cells.

05/05/16
20160120934 

Lung injury repair compositions and methods


The present invention provides a pharmaceutical composition comprising protein kinase c zeta (pkc-ζ) inhibitor and therapeutic methods for preventing or treating a pathological condition or symptom or for inducing proliferation of lung progenitor cells in a mammal by administering the pkc-ζ inhibitor.. .
University Of Iowa Research Foundation


05/05/16
20160120875 

Substituted (e)-n'-(1-phenylethylidene)benzohydrazide analogs as histone demethylase inhibitors


Methods of treatment of disorders of uncontrolled cellular proliferation, including cancer, by administering substituted (e)-n′-(1-phenylethylidene)benzohydrazide analogs, derivatives thereof, and related compounds to mammals in need thereof.. .
University Of Utah Research Foundation


05/05/16
20160120874 

Agents for treating multiple myeloma


The present invention relates to the use of compounds of a cannabinoid nature for inhibiting viability with increasing doses of myeloma cell lines. Furthermore, said compounds have been shown not to affect cd34+ cells (normal hematopoietic progenitors) in terms of viability and proliferation.
Servicio Andaluz De Salud


04/28/16
20160115559 

Bacterium belonging to genus lactobacillus


A lactobacillus pentosus tua4337l strain (accession number: nite bp-1479), characterized in that the strain has proliferation ability in the small intestines and/or the large intestine, and preferably the small intestines, after having survived in the intestinal tract. Since the lactic acid bacteria of the present invention have proliferation ability in the intestinal tract, when ingested in the body, the lactic acid bacteria survive to the intestinal tract and proliferate, whereby the fat absorption can be continuously blocked, and the weight gains can be effectively blocked, so that the lactic acid bacteria can be suitably used for the purposes of dieting effects..
Suntory Holdings Limited


04/28/16
20160115251 

Heparan sulphates


A novel class of structurally and functionally related isolated heparan sulphate is disclosed. The novel class of heparan sulphates has been found to bind fgf2 and enhance the proliferation of stem cells whilst maintaining their pluripotency/multipotency..
Agency For Science, Technology And Research


04/28/16
20160115202 

Chemical synthesis and screening of bicyclic peptide libraries


Disclosed herein are bicyclic peptide compounds, compositions comprising same, methods for making same, and libraries comprising same. The disclosed compounds, in various aspects, are useful for treating a variety of disorders, including inflammatory disorders, autoimmune disorders, and disorders of uncontrolled cellular proliferation.
Ohio State Innovation Foundation


04/28/16
20160115168 

Novel fused pyrimidine compound or salt thereof


Provided is a novel compound having btk inhibitory action and a cell proliferation suppressing effect. Also provided is a medicine useful for the prevention and/or treatment of a disease associated with btk, particularly cancer, based on btk inhibitory action.
Taiho Pharmaceutical Co., Ltd.


04/28/16
20160115167 

Bmp inhibitors and methods of use thereof


The present invention provides small molecule inhibitors of bmp signaling. These compounds may be used to modulate cell growth, differentiation, proliferation, and apoptosis, and thus may be useful for treating diseases or conditions associated with bmp signaling, including inflammation, cardiovascular disease, hematological disease, cancer, and bone disorders, as well as for modulating cellular differentiation and/or proliferation.
The General Hospital Corporation


04/28/16
20160113958 

Modulators of adp-dependent glucokinase (adpgk) and glycerol-3-phosphate dehydrogenase (gpd2) for therapy


Described are compounds capable of modulating (a) the biological activity of adp-dependent glucokinase (adpgk) and/or glycerol-3-phosphate dehydrogenase (gpd2) or (b) the expression of the gene encoding adpgk or gpd2 for use in treating a disease (a) associated with aberrant cell proliferation, e.g., a neoplasm, or (b) of the immune system, e.g., an autoimmune disease.. .
Deutsches Krebsforschungszentrum Stiftung Des Öffentlichen Recht


04/28/16
20160113955 

Compositions and methods for immunotherapy


The present invention provides novel immunotherapeutic compositions and methods useful for treating or preventing microbial infections, weakened immune systems, diseases in which cells have become obligately anerobic and cellular proliferative disorders including cancer. The immunotherapeutics herein use benzaldehyde derivatives, precursors and intermediaries alone or in combination with additional therapeutic agents to stimulate the immune system and inhibit cellular proliferation.

04/21/16
20160110763 

Extracting product purchase information from electronic messages


Improved systems and methods for extracting product purchase information from electronic messages transmitted between physical network nodes to convey product purchase information to designated recipients. These examples provide a product purchase information extraction service that is able to extract product purchase information from electronic messages with high precision across a wide variety of electronic message formats and thereby solve the practical problems that have arisen as a result of the proliferation of different electronic message formats used by individual merchants and across different merchants and different languages.

04/21/16
20160110762 

Extracting product purchase information from electronic messages


Improved systems and methods for extracting product purchase information from electronic messages transmitted between physical network nodes to convey product purchase information to designated recipients. These examples provide a product purchase information extraction service that is able to extract product purchase information from electronic messages with high precision across a wide variety of electronic message formats and thereby solve the practical problems that have arisen as a result of the proliferation of different electronic message formats used by individual merchants and across different merchants and different languages.



Proliferation topics: Proliferation, Cell Proliferation, Differentiation, Cancer Cell, Antibodies, Progesterone, Specificity, Cancer Cells, Antimicrobial, Lymphocyte, Cell Differentiation, Homogeneous, Amino Acids, Wound Healing, Epithelial

Follow us on Twitter
twitter icon@FreshPatents

###

This listing is a sample listing of patent applications related to Proliferation for is only meant as a recent sample of applications filed, not a comprehensive history. There may be associated servicemarks and trademarks related to these patents. Please check with patent attorney if you need further assistance or plan to use for business purposes. This patent data is also published to the public by the USPTO and available for free on their website. Note that there may be alternative spellings for Proliferation with additional patents listed. Browse our RSS directory or Search for other possible listings.


1.0572

5108

3 - 0 - 101