Images List Premium Download Classic

Proliferation

Proliferation-related patent applications - as published by the U.S. Patent and Trademark Office (USPTO).


loading
System and method of measuring cell viability and growth
Transgenex Nanobiotech, Inc.
February 15, 2018 - N°20180045681

A novel sh-saw biosensor capable of non-invasive and touch-free detection of cancer cell viability and growth or proliferation in two-dimensional (2d) and three-dimensional (3d) cell cultures as well as stem cell regeneration as it pertains to cancer cell biology and anti-cancer drug development is presented. The biosensor includes two pairs of resonators including interdigital transducers reflecting fingers to quantify mass ...
Tools and methods for using cell division loci to control proliferation of cells
Sinai Health System
February 15, 2018 - N°20180044686

The present disclosure provides molecular tools, methods and kits for using cell division loci (cdls) to control cell proliferation in animal cells. Cdls, as provided herein, are loci whose transcription product(s) are expressed during cell division. Cdls may be genetically modified, as described herein, to comprise a negative selectable marker and/or an inducible activator-based gene expression system, which ...
Pericyte long non-coding rnas
Johann Wolfgang Goethe-universität Frankfurt Am Main
February 15, 2018 - N°20180044672

The present invention provides novel non-coding rnas (lncrna) that were identified to be expressed in pericytes upon hypoxia. The lncrna of the invention positively affect platelet-derived growth factor receptor (pdgfr) beta expression, pericytes proliferation and pericyte recruitment to endothelial cells. The invention provides inhibitors of the lncrna for use in the treatment of diseases mediated by pdgfr expression. For example ...
Proliferation Patent Pack
Download 113+ patent application PDFs
Proliferation Patent Applications
Download 113+ Proliferation-related PDFs
For professional research & prior art discovery
inventor
  • 113+ full patent PDF documents of Proliferation-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
New pyridinones and isoquinolinones as inhibitors of the bromodomain brd9
Boehringer Ingelheim International Gmbh
February 15, 2018 - N°20180044335

The present invention encompasses compounds of general formula (i) wherein the groups r1 to r9, x1 and x2 have the meanings given in the claims and in the specification. The compounds of the invention are suitable for the treatment of diseases characterized by excessive or abnormal cell proliferation, e. G. Cancer, pharmaceutical preparations containing such compounds and their uses as ...
Biguanide compound and use thereof
Immunomet Therapeutics Inc.
February 15, 2018 - N°20180044283

The present invention relates to a guanidine compound and a use thereof, and more specifically, to a guanidine derivative showing excellent effects of inhibiting cancer cell proliferation, cancer metastasis, and cancer recurrence; a preparation method thereof; and a pharmaceutical composition containing the same as an active ingredient. Compared to existing drugs, the guanidine derivative according to the present invention shows ...
Biaryl compositions and methods for modulating a kinase cascade
Athenex, Inc.
February 15, 2018 - N°20180042934

The application relates to biaryl compounds, pharmaceutical compositions comprising the compounds, and methods of use the compounds for treating cell proliferation disorders.
Proliferation Patent Pack
Download 113+ patent application PDFs
Proliferation Patent Applications
Download 113+ Proliferation-related PDFs
For professional research & prior art discovery
inventor
  • 113+ full patent PDF documents of Proliferation-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
Oligonucleotide compositions and uses thereof
Miragen Therapeutics, Inc.
February 08, 2018 - N°20180037890

The present invention provides oligonucleotide inhibitors of mir-155 and compositions thereof. The invention further provides methods for treating cancer such as a t cell lymphoma in a subject by administering to the subject an oligonucleotide inhibitor of mir-155. The invention also provides methods for reducing or inhibiting the proliferation of malignant t cells by administering an oligonucleotide inhibitor of mir-155.
Cell culture method for mesenchymal stem cells
Mesoblast International Sàrl
February 08, 2018 - N°20180037867

The present disclosure relates to methods, cell culture medium and compositions that promote cell proliferation during fetal bovine serum free cell culture.
Ckap4-molecular-targeted antitumor agent
Osaka University
February 08, 2018 - N°20180037649

Disclosed is to identify a target molecule that is involved in dkk1-induced hyperproliferation of tumor cells to provide a novel antitumor agent. Cytoskeleton-associated protein 4 (ckap4) specifically regulates the hyperproliferation effects that are induced by dickkopf-related protein 1 (dkk1), and proliferation of tumor cells can be suppressed by inhibiting expression or function of ckap4 in the tumor cells.
Advanced methods and systems for treating cell proliferation disorders
February 08, 2018 - N°20180036408

Wherein the plasmonics-active agent enhances or modifies the applied initiation energy, such that the enhanced or modified initiation energy activates the activatable pharmaceutical agent by the simultaneous two photon absorption event in situ, thus causing the predetermined cellular change to occur, wherein said predetermined cellular change treats the cell proliferation related disorder; and the use of plasmonics enhanced photospectral therapy (...
Anti-tumor vaccine derived from normal cells
Cytovac A/s
February 08, 2018 - N°20180036397

A composition for inducing an immune response in a mammal, comprises lymphoid cells in which expression of tumor antigens has been chemically induced. The tumor antigens are induced in proliferating normal lymphoid cells, especially during the log phase of proliferation. The proliferation of the normal lymphoid cells is stimulated by normal mature dendritic cells. Most conveniently, the lymphoid cells are ...
Methods and compositions for stimulation of cell proliferation and provision of biologically active mixtures of ...
Sanbio, Inc.
February 08, 2018 - N°20180036378

Disclosed herein are methods and compositions for providing mixtures of fgf2 isoforms that are biologically active. The biological activities include, but are not limited to, stimulation of proliferation of neural precursor cells, stimulation of proliferation of endothelial cells, stimulation of development of neural precursor cells, and stimulation of development of astrocytes.
Method of treating conditions with kinase inhibitors
February 08, 2018 - N°20180036317

Or a prodrug, pharmaceutically acceptable salt, racemic mixtures or enantiomers of said compound. The compounds of formula i are capable of modulating tyrosine kinase signal transduction in order to regulate, modulate and/or inhibit abnormal cell proliferation.
Proliferation Patent Pack
Download 113+ patent application PDFs
Proliferation Patent Applications
Download 113+ Proliferation-related PDFs
For professional research & prior art discovery
inventor
  • 113+ full patent PDF documents of Proliferation-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
Icos binding proteins
Centre National De La Recherche Scientifique (cnrs)
February 01, 2018 - N°20180030136

The present invention relates to an icos binding protein or antigen binding portion thereof that is an agonist to human icos and does not induce complement, adcc, or cdc when placed in contact with a t cell in vivo and methods of treating cancer, infectious disease and/or sepsis with said icos binding protein or antigen binding portion thereof. Further ...
Chemical synthesis and screening of bicyclic peptide libraries
Ohio State Innovation Foundation
February 01, 2018 - N°20180030094

Disclosed herein are bicyclic peptide compounds, compositions comprising same, methods for making same, and libraries comprising same. The disclosed compounds, in various aspects, are useful for treating a variety of disorders, including inflammatory disorders, autoimmune disorders, and disorders of uncontrolled cellular proliferation. This abstract is intended as a scanning tool for purposes of searching in the particular art and is ...
Top plate for cooking device
Nippon Electric Glass Co., Ltd.
February 01, 2018 - N°20180029927

A technical object of the present invention is to devise a top plate for a cooking appliance that can suppress proliferation of bacteria or mold. In order to achieve the technical object, the top plate for a cooking appliance of the present invention includes: a crystallized glass substrate having a cooking surface on which a cooking device is placed; and ...
Skin-regenerating material comprising synergistic combination of metal oxides
Argaman Technologies Ltd.
February 01, 2018 - N°20180028712

Provided are materials including cell proliferation properties. The materials may include a polymer having incorporated therein a synergistic combination of at least two metal oxide powders, including a mixed oxidation state oxide of a first metal and a single oxidation state oxide of a second metal. The mixed oxidation state oxide may constitute from about 25% wt. To about 75% wt. Of ...
Antibacterial puff for cosmetics
Dmcosmetics Co., Ltd.
February 01, 2018 - N°20180027941

An antibacterial puff for cosmetics in which an antibacterial agent is included in a foam composed of polyurethane and the like is disclosed. More particularly, an antibacterial puff reduces excessive consumption of a cosmetic material caused by absorption of a puff, which is a disadvantage of an existing puff, and includes an antibacterial material capable of suppressing proliferation of microorganisms.
Compositions and methods for combination therapy with prostate-specific membrane antigen binding proteins
Aptevo Research And Development Llc
January 25, 2018 - N°20180022819

The present disclosure relates to combination treatments with anti-androgen therapeutics, including enzalutamide, and prostate-specific membrane antigen (psma)-binding polypeptides including multi-specific polypeptide therapeutics that specifically target cells expressing psma and are capable of redirecting t-cell cytotoxicity. Such therapeutics are useful for the treatment of prostate cancer (e. G., castration-resistant prostate cancer). In one embodiment, multi-specific polypeptide therapeutics bind both psma-expressing ...
Novel fluorine-containing bisphosphonic acid derivative and use thereof
January 25, 2018 - N°20180022769

Wherein each symbol is as defined in the description, can efficiently induce proliferation of peripheral blood γδ t cells that express vγ2vδ2 t cell receptor having superior cytotoxicity against tumor cells and virus infected cells, immunize tumor cells and virus infected cells, and can induce cytotoxicity by γδ t ...
Inhibition of yap for breaking tumor immune tolerance
The Johns Hopkins University
January 25, 2018 - N°20180021306

Yes-associated protein (yap), a downstream co-activator of the hippo pathway, is highly expressed in the treg cell subset, and is critical to maintain its suppressive activity. Originally discovered in drosophila melanogaster, the hippo signaling pathway is a major regulator of cellular growth and proliferation in mammals. Loss of yap expression in treg cells can lead to superior anti-tumor immune responses, ...
Loading