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Proliferation patents



      
           
This page is updated frequently with new Proliferation-related patent applications. Subscribe to the Proliferation RSS feed to automatically get the update: related Proliferation RSS feeds. RSS updates for this page: Proliferation RSS RSS


Date/App# patent app List of recent Proliferation-related patents
03/05/15
20150065344
 Organic composition for use with plants patent thumbnailnew patent Organic composition for use with plants
An organic composition for use as ground covering capable of supporting plant life is presented. The organic composition is a mixture of filtration waste and topsoil, dirt, manure, wood chips, leaves, and/or sand.
03/05/15
20150064700
 Markers for pre-cancer and cancer cells and the method to interfere with cell proliferation therein patent thumbnailnew patent Markers for pre-cancer and cancer cells and the method to interfere with cell proliferation therein
A novel family of human mitochondrial rnas, referred to as chimeric rnas, which are differentially expressed in normal, pre-cancer and cancer cells, are described. Oligonucleotides targeted to the chimeric rnas are provided.
Andes Biotechnologies S.a.
03/05/15
20150064196
 Substituted hetero-bicyclic compounds, compositions and medicinal applications thereof patent thumbnailnew patent Substituted hetero-bicyclic compounds, compositions and medicinal applications thereof
These compounds are useful in the treatment, prevention, prophylaxis, management, or adjunct treatment of all medical conditions related to inhibition of bruton's tyrosine kinase (btk), such as inflammatory and/or autoimmune disorder, cell proliferation, rheumatoid arthritis, psoriasis, psoriatic arthritis, transplant rejection, graft-versus-host disease, multiple sclerosis, inflammatory bowel disease, allergic diseases, asthma, type 1 diabetes, myasthenia gravis, hematopoetic disfunction, b-cell malignancies, systemic lupus, erythematosus or other disorders.. .
03/05/15
20150064147
 Crosslinked hyaluronic acid-collagen gels for improving tissue graft viability and soft tissue augmentation patent thumbnailnew patent Crosslinked hyaluronic acid-collagen gels for improving tissue graft viability and soft tissue augmentation
Hydrogels comprising a macromolecular matrix and water may be used to augment soft tissue of a human being, promote or support cell or tissue viability or proliferation, create space in tissue, and for other purposes. A macromolecular matrix may comprise a hyaluronic acid component crosslinked to a collagen component..
Allergan, Inc.
03/05/15
20150064139
 Cell potency assay for therapeutic potential patent thumbnailnew patent Cell potency assay for therapeutic potential
The invention provides cell potency assays for measuring, determining, identifying, confirming, or validating the therapeutic potential of a cell population. Cell potency assays may be performed with various types of cells, including stem or progenitor cells, such as, for example, hematopoietic stem or progenitor cells.
Fate Therapeutics, Inc.
03/05/15
20150064134
 Compositions and methods for preventing or treating diseases, conditions, or processes characterized by aberrant fibroblast proliferation and extracellular matrix deposition patent thumbnailnew patent Compositions and methods for preventing or treating diseases, conditions, or processes characterized by aberrant fibroblast proliferation and extracellular matrix deposition
The described invention provides compositions and methods for treating asthma, a disease, condition or pathologic process whose progression is characterized by one or more of aberrant fibroblast proliferation and extracellular matrix deposition producing constriction in an airway, airway remodeling, and airway obstruction in lung tissue. The method includes administering a pharmaceutical composition comprising a therapeutic amount of a polypeptide having the amino acid sequence yaraaarqarakalarqlgvaa (seq id no: 1) or functional equivalent thereof, and a pharmaceutically acceptable carrier, wherein the therapeutic amount of the polypeptide is effective to reduce the constriction of small airway dimensions and airway obstruction, treat airway remodeling, or a combination thereof..
02/26/15
20150058171
 Online marketplace for services patent thumbnailOnline marketplace for services
A method and system of providing for ratings and recommendations made by knowledgeable third parties as to the competency and fitness of a service provider for the particular project for which the service buyer is currently seeking service providers, together with the aggregation of that data with other data (including other ratings for the particular project, ratings made by service buyers after project completion, and all such data with respect to all projects for the service provider), facilitates the matching of highly qualified service providers with projects/jobs. In addition, because the system harnesses the collective wisdom of all peer raters and expert raters and uses methodologies to encourage the proliferation of accurate and useful ratings data with respect to service providers, the system is able to utilize the power of the internet to collect and aggregate these opinions and ratings/rankings in a manner not easily replicable through offline methods.
02/26/15
20150057751
 Acellular dermal graft patent thumbnailAcellular dermal graft
An acellular dermal graft is provided. The acellular dermal graft may be useful in minimizing side effects caused after transplantation since an environment favorable for formation of new blood vessels and proliferation of autologous tissues is provided by forming a multi-penetration structure in an acellular dermal tissue, removing a basement membrane layer and/or subjecting corners to slope cutting, and transplantation is stably performed within a short transplantation time due to improved extensibility and flexibility of tissues.
L&c Bio Co., Ltd.
02/26/15
20150056703
 Fiber scaffolds for enhancing cell proliferation in cell culture patent thumbnailFiber scaffolds for enhancing cell proliferation in cell culture
A substrate for culturing cells that includes at least one fiber scaffold adapted to be contained within a disposable or non-disposable bioreactor, wherein the fiber scaffold further includes polymer fibers that have been created by electrospinning, and wherein the orientation of the fibers in the scaffold relative to one another is generally parallel, random, or both.. .
02/26/15
20150056697
 Pluripotent stem cells and  stimulating and extracting non-embryonic pluripotent stem cells from mammal blood and using reconstituted pluripotent stem cells to treat diseases including chronic obstructive pulmonary disease patent thumbnailPluripotent stem cells and stimulating and extracting non-embryonic pluripotent stem cells from mammal blood and using reconstituted pluripotent stem cells to treat diseases including chronic obstructive pulmonary disease
Stimulating tissue resident pluripotent stem cells in a manner that the respective subject (e.g., human) acts as its own sterile bioreactor for in vivo stem cell proliferation thus eliminating the need to isolate, cultivate, maintain, proliferate and release stem cells ex vivo. The stimulation mobilizes excess pluripotent stem cells into the peripheral vasculature where the pluripotent stem cells can either migrate to damaged tissues and/or be harvested by simple venipuncture, thus eliminating potential morbidity and mortality elicited from harvesting tissue from solid tissue sites.
Royal Medical Group, Pllc
02/26/15
20150056222

Anti-prlr antibodies and uses thereof


The present invention provides antibodies that bind to prolactin receptor (prlr) and methods of using the same. According to certain embodiments, the antibodies of the invention bind human prlr with high affinity.
Regeneron Pharmaceuticals, Inc.
02/26/15
20150056221

Anti-prlr antibodies and uses thereof


The present invention provides antibodies that bind to prolactin receptor (prlr) and methods of using the same. According to certain embodiments, the antibodies of the invention bind human prlr with high affinity.
Regeneron Pharmaceuticals, Inc.
02/26/15
20150056161

Regeneration of endogenous myocardial tissue


This invention provides a method of treating a disorder of a subject's heart involving loss of cardiomyocytes which comprises administering to the subject a composition comprising an amount of a human stromal derived factor-1 and an amount of a human granulocyte-colony stimulating factor, the composition being administered in an amount effective to cause proliferation of cardiomyocytes within the subject's heart so as to thereby treat the disorder. This invention also provides a method of treating a subject suffering from a disorder of a tissue involving loss and/or apoptosis of cells of the tissue which comprises administering to the subject a composition comprising an amount of an agent which induces phosphorylation and/or activation of protein kinase b, or an agent which induces phosphorylation and/or activation of an extracellular signal-regulated protein kinase, or an agent which induces activation of cxcr4..
The Trustees Of Columbia University In The City Of New York
02/19/15
20150051558

Composition and corneal proliferation


Disclosed herein in exemplary embodiments are methods and compositions for repairing or treating a defected cornea in a patient in need. The methods and compositions including, for example, administering a dose of a composition to the patient, wherein the composition comprises may be administered to an intraocular area of the patient via a container having a spout for ophthalmic delivery.
University Of Central Florida Research Foundation, Inc.
02/19/15
20150051208

Pyridinones


Wherein the groups r1 to r3 and x1 through x6 have the meanings given in the claims and in the specification. The compounds of the invention are suitable for the treatment of diseases characterized by excessive or abnormal cell proliferation pharmaceutical preparations containing such compounds and their uses as a medicament..
02/19/15
20150051154

Alkylating agents


The present invention relates to a novel class of alkylating agents comprising a thieno-indole moiety linked to a dna-binding moiety, which have cytotoxic activity and are useful in treating diseases such as cancer, cellular proliferation disorders and viral infections. The present invention also provides methods for preparing these compounds, pharmaceutical compositions comprising them and methods of treating diseases utilizing such compounds or the pharmaceutical composition containing them.
Nerviano Medical Sciences S.r.l.
02/19/15
20150051145

Use of 1,3-diphenylprop-2-en-1-one derivatives for treating liver disorders


The invention provides 1,3-diphenylprop-2-en-1-one derivatives and pharmaceutical compositions comprising the same for treating liver disorders, in particular those requiring the reduction of plasma level of biochemical markers such as aminotransferases. The 1,3-diphenylprop-2-en-1-one derivatives of general formula (i) have hepatoprotective properties and can be used in methods for treating liver disorders involving the pathological disruption, inflammation, degeneration, and/or proliferation of liver cells, such as liver fibrosis or fatty liver disease..
Genfit
02/19/15
20150050744

Diagnostic agent and diagnostic irritable bowel syndrome induced by abnormal proliferation of enterobacteria


[selected drawing] none. .
02/19/15
20150050407

Mixed lactic acid bacterial culture fluid composition for delayed ripening of kimchi and making kimchi using same


Provided are: a culture fluid composition for delaying the ripening of kimchi, which contains a mixed lactic acid bacterial culture fluid with which a culture fluid containing six types of lactic acid bacteria is mixed to be capable of specifically inhibiting the proliferation of lactic acid bacteria in fermented kimchi; vitamin b1; and lactic acid and a method for making kimchi using same for delaying the ripening of kimchi.. .
Ourhome Co.,ltd.
02/19/15
20150050279

B-cell receptor complex binding proteins containing t-cell epitopes


The present invention relates to a polypeptide comprising a) a binding peptide binding to at least one protein selected from the group consisting of cd22, cd19, cd20, and cd21, and b) an immunogenic peptide comprising at least one t-cell epitope for use in vaccination of a subject against b-cell hyperproliferation or for use in the modulation of the immune response in a subject. The present invention further relates to a polynucleotide and a vector encoding said polypeptide and a host cell comprising the same.
Deutsches Krebsforschungszentrum
02/19/15
20150050252

Pluripotent stem cells and stimulating and extracting non-embryonic pluripotent stem cells from mammal blood and using reconstituted pluripotent stem cells to treat diseases including chronic obstructive pulmonary disease


Stimulating tissue resident pluripotent stem cells in a manner that the respective subject (e.g., human) acts as its own sterile bioreactor for in vivo stem cell proliferation thus eliminating the need to isolate, cultivate, maintain, proliferate and release stem cells ex vivo. The stimulation mobilizes excess pluripotent stem cells into the peripheral vasculature where the pluripotent stem cells can either migrate to damaged tissues and/or be harvested by simple venipuncture, thus eliminating potential morbidity and mortality elicited from harvesting tissue from solid tissue sites.
Royal Medical Group, Pllc
02/19/15
20150050239

Substituted pyrazolone compounds and methods of use


The present invention provides novel substituted pyrazolone compounds, pharmaceutical acceptable salts and formulations thereof useful in modulating the protein tyrosine kinase activity, and in modulating cellular activities such as proliferation, differentiation, apoptosis, migration and invasion. The invention also provides pharmaceutically acceptable compositions comprising such compounds and methods of using the compositions in the treatment of hyperproliferative disorders in mammals, especially humans..
Sunshine Lake Pharma Co., Ltd.
02/12/15
20150045379

Indazole inhibitors of the wnt signal pathway and therapeutic uses thereof


Indazole compounds for treating various diseases and pathologies are disclosed. More particularly, the present invention concerns the use of an indazole compound or analogs thereof, in the treatment of disorders characterized by the activation of wnt pathway signaling (e.g., cancer, abnormal cellular proliferation, angiogenesis, alzheimer's disease and osteoarthritis), the modulation of cellular events mediated by wnt pathway signaling, as well as genetic diseases due to mutations in wnt signaling components.
Samumed, Llc
02/12/15
20150045374

2- (tert - butoxy) -2- (7 -methylquinolin- 6 - yl) acetic acid derivatives for treating aids


The invention provides compounds and salts thereof as d herein. The invention also provides pharmaceutical compositions comprising a compound disclosed herein, processes for preparing compounds disclosed herein, intermediates useful for preparing compounds disclosed herein and therapeutic methods for treating an hiv infection, treating the proliferation of the hiv virus, treating aids or delaying the onset of aids or arc symptoms in a mammal using compounds disclosed herein..
Gilead Sciences, Inc.
02/12/15
20150044770

Method for selective cell attachment/detachment, cell patternization and cell harvesting by means of near infrared rays


The present invention relates to a method for selective cell attachment/detachment, cell patternization and cell harvesting by means of near infrared rays. More particularly, conducting polymers or metal oxides having exothermic characteristics upon irradiation of near infrared light is used as a cell culture scaffold, thus selectively attaching/detaching cells without an enzyme treatment.
Industry-academic Cooperation Foundation Yonsei University
02/12/15
20150044233

Ganglioside gd2 as a marker and target on cancer stem cells


Methods for determining the presence of cancer stem cells by detecting gd2 expression. Also provided are methods for reducing proliferation of cancer stem cells by contacting the cells with a gd2 targeting agent, such as an anti-gd2 antibody or a gd3 synthase inhibitor.
Board Of Regents , The University Of Texas System
02/05/15
20150038708

Substituted 2-hydroxy-4-(2-(phenylsulfonamido)acetamido)benzoic acid analogs as inhibitors of stat protein


In one aspect, the invention relates to substituted 2-hydroxy-4-(2-(phenylsulfonamido)acetamido)benzoic acid analogs, derivatives thereof, and related compounds, which are useful as inhibitors of stat protein activity; synthetic methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of treating disorders of uncontrolled cellular proliferation associated with a stat protein activity dysfunction using the compounds and compositions. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention..
The Governing Council Of The University Of Toronto
02/05/15
20150038541

Composition and methods for cell modulation


Composition and methods for affecting cell proliferation, metabolism or sensitization, including the potentiation of proteasome inhibitor therapy for the treatment of disease caused by deregulation of ubiquitin-proteasome systems, in a cell or subject. The composition includes a compound in combination with a ubiquitin-proteasome inhibitor.
Aposignal Bioscience Llc
02/05/15
20150037435

Culture medium of adipose-derived stem cell, preparing the same, and composition including the same for promoting hair growth


Provided are a culture medium of an adipose-derived stem cell, a method for preparing the same, and a composition for promoting hair growth, in which the composition includes the culture medium. The adipose-derived stem cell (adsc-t) according to the present invention exhibits long lifespan, improved cell proliferation rate, and extended proliferation period, as compared with a primary adipose-derived stem cell (adsc), and thus, the adipose-derived stem cell (adsc-t) can be usefully used for the study about the adipose-derived stem cell and the mass production of the culture medium of the adipose-derived stem cell.
Changwon National University Industry Academy Cooperation Corps
02/05/15
20150037399

Novel use of pipoxolan and its pharmaceutical composition


The present disclosure concerns the novel use of pipoxolan and its pharmaceutical composition. Pipoxolan is useful therapeutic drugs for pathological conditions caused by vascular smooth muscle cell proliferation and migration to relieve a body appeared vascular injury, cerebrovascular ischemia, intimal hyperplasia, atherosclerotic stenosis, cerebral ischemia, and stroke..
China Medical University
02/05/15
20150037382

Microsphere skin treatment


This application provides a microsphere suitable for tissue engineering that comprises connective tissue growth factor (ctgf). Also provided is a matrix, material or scaffold suitable for tissue engineering that comprises connective tissue growth factor (ctgf) and basic fibroblast growth factor (bfgf).
The Trustees Of Columbia University In The City Of New York
02/05/15
20150037290

Methods of modulating smooth muscle cell proliferation and differentiation


The present disclosure provides methods of inducing smooth muscle cell differentiation. The present disclosure provides genetically modified cells comprising exogenous mir-143 and/or mir-145 nucleic acids; and artificial tissues comprising the genetically modified cells.
The J. David Gladstone Institutes
02/05/15
20150037280

Substituted pyrazolone compounds and methods of use


The present invention provides novel substituted pyrazolone compounds, pharmaceutical acceptable salts and formulations thereof useful in modulating the protein tyrosine kinase activity, and in modulating cellular activities such as proliferation, differentiation, apoptosis, migration and invasion. The invention also provides pharmaceutically acceptable compositions comprising such compounds and methods of using the compositions in the treatment of hyperproliferative disorders in mammals, especially humans..
Calitor Sciences, Llc
01/29/15
20150031682

Anti-malarial agents


The present invention is related to a use of aminopyrazine derivatives in the manufacture of a medicament for preventing or treating malaria. Specifically, the present invention is related to aminopyrazine derivatives useful for the preparation of a pharmaceutical formulation for the inhibition of malaria parasite proliferation..
Mmv Medicines For Malaria Venture
01/29/15
20150030854

Vitamin b6-coupled poly(ester amine) as gene carrier and application in cancer gene therapy


The present invention relates to a vitamin b6-coupled poly(ester amine) (vbpea) as a gene carrier and a method for preparing the gene carrier. Moreover, the present invention relates to a gene delivery complex comprising a therapeutic gene coupled to the gene carrier and a pharmaceutical formulation for gene therapy, which comprises the gene delivery complex as an active ingredient.
Snu R&db Foundation
01/29/15
20150030688

Honey and growth factor eluting scaffold for wound healing and tissue engineering


Tissue engineering structures with biologically favorable structural and chemical properties are disclosed. More particularly, the present disclosure is directed to tissue engineered scaffolds having a fiber support and honey.
Saint Louis University
01/29/15
20150030634

Proliferating agent for monocyte, culture medium for proliferating monocyte, producing monocyte, producing dendritic cell, and producing dendritic cell vaccine


The purpose of the present invention is to provide a means for proliferating a monocyte with high efficiency and in a simple manner. The present invention provides a proliferating agent for a monocyte, which consists of at least one component selected from flt-3l, il-3 and ifn-γ and can be used before a treatment for differentiation of a monocyte into a dendritic cell.
Hakushikouseikai Foundation
01/29/15
20150030585

Compositions including triciribine and one or more platinum compounds and methods of use thereof


This application encompasses combination therapies including triciribine and related compounds and one or more platinum compounds and compositions with reduced toxicity for the treatment and prevention of tumors, cancer, and other disorders associated with abnormal cell proliferation.. .
University Of South Florida
01/22/15
20150025230

Single nucleotide polymorphisms in brca1 and cancer risk


The invention provides methods for identifying mutations, such as single nucleotide polymorphisms (snps), within breast and ovarian cancer associated genes that modify the binding efficacy of micrornas (mirnas). In a preferred embodiment, methods of the invention identify a snp that decreases expression of the brca1 gene by increasing or decreasing the binding efficacy of at least one mirna.
Yale University
01/22/15
20150023951

Anti-vegf antibodies


Humanized and variant anti-vegf antibodies and various uses therefor are disclosed. The anti-vegf antibodies have strong binding affinities for vegf; inhibit vegf-induced proliferation of endothelial cells in vitro; and inhibit tumor growth in vivo..
Genentech, Inc.
01/22/15
20150023868

Hif inhibitors and use thereof


The present invention is directed to hif inhibitors and methods of preventing cell proliferation, reducing inflammation, and treating an angiogenic disease or disorders.. .
The General Hospital Corporation
01/15/15
20150018364

Control of hypoxia-inducible gene expression with oligooxopiperazine nonpeptidic helix mimetics


The present invention relates to oligooxopiperazines that mimic helix αb of the c-terminal transactivation domain of hif-1α. Also disclosed are pharmaceutical compositions containing these oligooxopiperazines and methods of using these oligooxopiperazines (e.g., to reduce gene transcription, treat or prevent disorders mediated by interaction of hif-1α with creb-binding protein and/or p300, reduce or prevent angiogenesis in a tissue, induce apoptosis, and decrease cell survival and/or proliferation)..
University Of Southern California
01/15/15
20150018310

Substituted 3-(5-membered unsaturated heterocyclyl-1, 3-dihydro-indol-2-one's and derivatives thereof as kinase inhibitors


The present invention relates to organic molecules capable of modulating tyrosine kinase signal transduction in order to regulate, modulate and/or inhibit abnormal cell proliferation.. .
Allergan, Inc.
01/15/15
20150018290

Inducers of hematopoiesis and fetal globin production for treatment of cytopenias and hemoglobin disorders


The present invention generally relates to compositions containing chemical compounds and compositions and pharmaceutical formulations of the compounds which increase the expression of total hemoglobin or globin protein such as embryonic or fetal globin, or the proliferation of hemoglobin expressing and other blood cells. These compositions can be used to treat or prevent the symptoms associated with anemia, sickle cell diseases, thalassemia, and other blood cell deficiencies and blood disorders.
Trustees Of Boston University
01/15/15
20150018286

Antitumor peptide and use thereof


This invention provides an antitumor peptide and an antitumor composition that includes the peptide for suppressing proliferation of at least one species of tumor cells. The antitumor composition provided by this invention includes an antitumor peptide capable of inducing formation of multipolar spindles in at least one species of tumor cells, and at least one species of pharmaceutically acceptable carrier, wherein the antitumor peptide is a synthetic peptide having an amino acid sequence selected from seq id nos: 1 to 22 or an amino acid sequence formed by substituting, deleting and/or adding one, two or three amino acid residues in/from/to the selected amino acid sequence..
Toagosei Co., Ltd.
01/15/15
20150018225

Cell adhesion inhibitor, cell proliferation inhibitor, and method and kit for examining cancer


According to one aspect of the present invention, there is provided a cell proliferation inhibitor or a cell adhesion inhibitor for a cancer cell, containing an antibody to a protein containing the same or substantially the same amino acid sequence as the amino acid sequence represented by seq id no: 2 or a partial peptide thereof. According to another aspect of the present invention, there is provided a cell adhesion inhibitor for a cancer cell, containing an antisense polynucleotide containing a complementary or substantially complementary base sequence to a base sequence of a polynucleotide encoding a protein containing the same or substantially the same amino acid sequence as the amino acid sequence represented by seq id no: 2 or a part thereof.


Popular terms: [SEARCH]

Proliferation topics: Proliferation, Cell Proliferation, Differentiation, Cancer Cell, Antibodies, Progesterone, Specificity, Cancer Cells, Antimicrobial, Lymphocyte, Cell Differentiation, Homogeneous, Amino Acids, Wound Healing, Epithelial

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This listing is a sample listing of patent applications related to Proliferation for is only meant as a recent sample of applications filed, not a comprehensive history. There may be associated servicemarks and trademarks related to these patents. Please check with patent attorney if you need further assistance or plan to use for business purposes. This patent data is also published to the public by the USPTO and available for free on their website. Note that there may be alternative spellings for Proliferation with additional patents listed. Browse our RSS directory or Search for other possible listings.
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