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Proliferation

Proliferation-related patent applications - as published by the U.S. Patent and Trademark Office (USPTO).


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Multi-axis piezoresistive force sensor
Koc Universitesi
November 30, 2017 - N°20170343431

A microelectromechanical system (mems) sensor device comprising at least one microelectromechanical system sensor to characterize intracellular dynamics and behavior of a living biological cell so as to quantitatively measure the mechanical strength thereof. The microelectromechanical system sensor being responsive to mechanical force changes during said cell's contraction, migration, proliferation and differentiation.
Methods of using microrna-199a
Stemirna Therapeutics Co., Ltd.
November 30, 2017 - N°20170342421

Provided herein are methods of treating a cancer in an individual. A microrna-199a oligonucleotide or mimic that increases the expression of microrna-199a in the cancer cell is administered to the individual. Also provided is a method of inhibiting proliferation of a cancer cell and treating a cell associated with a cancer. The cell is contacted with the microrna-199...
Methods of using microrna-141
Stemirna Therapeutics Co., Ltd.
November 30, 2017 - N°20170342417

Provided herein are methods of treating a cancer in an individual. A microrna-141 oligonucleotide or mimic that increases the expression of microrna-141 in the cancer cell is administered to the individual. Also provided is a method of inhibiting proliferation of a cancer cell and treating a cell associated with a cancer. The cell is contacted with the microrna-141 oligonucleotide or ...
Proliferation Patent Pack
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Proliferation Patent Applications
Download 113+ Proliferation-related PDFs
For professional research & prior art discovery
inventor
  • 113+ full patent PDF documents of Proliferation-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
Cyclic peptide specifically binding to apoptotic cells and use thereof
Kyungpook National University Industry-academic Co Operation Foundation
November 30, 2017 - N°20170340698

Provided is a cyclic peptide (cyclo [cys-gln-arg-pro-pro-arg-cys] peptide) comprised of the amino acid sequence of seq id no: 2; and a composition for apoptotic cell detection, drug delivery or imaging, containing the same as an active ingredient. The cyclic peptide (cyclo [cys-gln-arg-pro-pro-arg-cys] peptide has an excellent effect of binding to apoptotic cells, compared with a linear peptide thereof, thereby greatly facilitating ...
Method for improving intestinal health using extracts of codonopsis lanceolata
Korea Institute Of Science And Technology
November 30, 2017 - N°20170340690

Disclosed is a method for improving intestinal microflora, which includes administering an extract of codonopsis lanceolata of an amount effective for improving intestinal microflora to a subject in need thereof. The extract can promote the proliferation of beneficial intestinal bacteria and suppress the proliferation of harmful bacteria. Also, the extract can improve intestinal health or intestinal function and improve defecation ...
Novel shigatoxin-producing f18 type e. coli bacteriophage esc-cop-1 and use thereof for inhibiting proliferation of ...
Intron Biotechnology, Inc.
November 30, 2017 - N°20170340686

The present invention relates to a myoviridae bacteriophage esc-cop-1 that is isolated from the nature and can kill specifically shigatoxin-producing type f18 e. Coli strains, which has a genome represented by the nucleotide sequence of seq. Id. No: 1 (accession no: kctc 12662bp), and a method for preventing and treating the infections of shigatoxin-producing type f18 e. Coli using the composition ...
Proliferation Patent Pack
Download 113+ patent application PDFs
Proliferation Patent Applications
Download 113+ Proliferation-related PDFs
For professional research & prior art discovery
inventor
  • 113+ full patent PDF documents of Proliferation-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
Inhibitors of human phosphatidylinositol 3-kinase delta
Icos Corporation
November 30, 2017 - N°20170340633

Methods of inhibiting phosphatidylinositol 3-kinase delta isoform (pi3kδ) activity, and methods of treating diseases, such as disorders of immunity and inflammation, in which pi3kδ plays a role in leukocyte function are disclosed. Preferably, the methods employ active agents that selectively inhibit pi3kδ, while not significantly inhibiting activity of other pi3k ...
Preventing and treating inflammatory skin diseases
Tel Hashomer Medical Research Infrastructure And Services Ltd.
November 23, 2017 - N°20170335328

The present invention relates to methods of treating, preventing, reducing the severity of, reducing the incidence of, delaying the onset of, or reducing pathogenesis of an inflammatory skin disease, condition or lesion in a human subject, which include the step of administering to the subject a therapeutically effective amount of mi rna compositions. In addition, methods of this invention may ...
Growth factor-free proliferation and differentiation of neural stem cells on inorganic extracellular nanomatrices
Hong Kong Baptist University
November 23, 2017 - N°20170335279

The present invention provides nanostructures for use in proliferation and differentiation of neural stem cells. The present invention also provides method of proliferating and differentiating neural stem cells.
Fusion proteins containing recombinant cytotoxic rnases
Immunomedics, Inc.
November 23, 2017 - N°20170334996

Recombinant immunotoxins containing a cytotoxic rnase fused to an antibody or antibody fragment may be produced in mammalian cell culture. Surprisingly, immunotoxins containing a cytotoxic rnase fused to the n-terminus of one antibody variable domain can be prepared and retain the ability to specifically bind antigen. The immunotoxins may lie used in a variety of therapeutic methods for treating diseases ...
Cell-penetrating anti-dna antibodies and uses thereof inhibit dna repair
The United States Government Represented By The Department Of Veterans Affairs
November 23, 2017 - N°20170334981

Antibodies that penetrate cell nuclei and inhibit dna repair or interfere with dna metabolism are provided for treatment of cancer (both directly and by sensitizing cancer cells to dna-damaging treatments) or inhibiting or preventing viral infection, proliferation or metabolism. The method involves treating cells with a composition containing cell-penetrating anti-dna antibodies or derivatives thereof, alone or in combination with treatment ...
Ligand
Ucl Business Plc
November 23, 2017 - N°20170334964

The present invention provides a variant proliferation-inducing ligand (april), which has a higher binding affinity to bcma than wild-type april; and/or altered binding kinetics compared with wild-type april, and/or a higher bcma:taci (transmembrane activator and calcium modulator and cyclophilin ligand interactor) binding ratio than wild-type april and which comprises mutations at one or more of the following ...
Bmp inhibitors and methods of use thereof
Ucl Business Plc
November 23, 2017 - N°20170334918

The present invention provides small molecule inhibitors of bmp signaling. These compounds may be used to modulate cell growth, differentiation, proliferation, and apoptosis, and thus may be useful for treating diseases or conditions associated with bmp signaling, including inflammation, cardiovascular disease, hematological disease, cancer, and bone disorders, as well as for modulating cellular differentiation and/or proliferation. These compounds may ...
Proliferation Patent Pack
Download 113+ patent application PDFs
Proliferation Patent Applications
Download 113+ Proliferation-related PDFs
For professional research & prior art discovery
inventor
  • 113+ full patent PDF documents of Proliferation-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
Novel mitochondrial uncouplers for treatment of metabolic diseases and cancer
Pimera, Inc.
November 23, 2017 - N°20170334869

The present disclosure relates to benzamide compounds, prodrugs of the compounds, pharmaceutical compositions containing the compounds and/or the prodrugs and methods of using the compounds, prodrugs and pharmaceutical compositions in the treatment of diseases related to lipid metabolism including diabetes, non-alcholic fatty liver disease (nafld), non-alcholic steathohepatitis (nash), diseases caused by abnormal cell proliferation including cancer, psoriasis, and infectious ...
Tissue regeneration membrane
Hadasit Medical Research Services & Development Ltd.
November 23, 2017 - N°20170333603

The present invention relates to a membrane comprising at least one positively charged, synthetic, hydrophobic polymer, at least one hydrophilic polymer and at least one plasticizer; wherein said membrane is flexible and is capable of supporting at least one of cell adherence, cell proliferation or cell differentiation. The invention further relates to use of a membrane of the invention in ...
Novel conjugates of cc-1065 analogs and bifunctional linkers
Syntarga Bv
November 23, 2017 - N°20170333567

This invention relates to novel analogs of the dna-alkylating agent cc-1065 and to their conjugates. Furthermore this invention concerns intermediates for the preparation of said agents and conjugates. The conjugates are designed to release their (multiple) payload after one or more activation steps and/or at a rate and time span controlled by the conjugate in order to selectively deliver ...
Novel enteroinvasive e. coli bacteriophage esc-cop-4 and use thereof for inhibiting proliferation of enteroinvasive e. ...
Intron Biotechnology, Inc.
November 23, 2017 - N°20170333499

The present invention relates to a myoviridae bacteriophage esc-cop-4 that is isolated from the nature and can kill specifically enteroinvasive e. Coli strains, which has a genome represented by the nucleotide sequence of seq. Id. No: 1 (accession no: kctc 12663bp), and a method for preventing and treating the infections of enteroinvasive e. Coli using the composition comprising said bacteriophage as ...
Novel enterohemorrhagic e. coli bacteriophage esc-chp-1 and use thereof for inhibiting proliferation of enterohemorrhagic e. ...
Intron Biotechnology, Inc.
November 23, 2017 - N°20170333498

The present invention relates to a myoviridae bacteriophage esc-chp-1 that is isolated from the nature and can kill specifically enterohemorrhagic e. Coli strains, which has a genome represented by the nucleotide sequence of seq. Id. No: 1 (accession no: kctc 12660bp), and a method for preventing and treating the infections of enterohemorrhagic e. Coli using the composition comprising said bacteriophage as ...
Tricyclic lactams for use in hspc-sparing treatments for rb-positive abnormal cellular proliferation
G1 Therapeutics, Inc.
November 23, 2017 - N°20170333440

This invention is in the area of tricyclic lactam compounds for and methods of treating selected rb-positive cancers and other rb-positive abnormal cellular proliferative disorders while minimizing the deleterious effects on healthy cells, for example healthy hematopoietic stem cells and progenitor cells (hspcs), associated with current treatment modalities. In one aspect, treatment of select rb-positive cancers is disclosed using specific ...
1h-pyrazolo[3,4-b]pyridines and therapeutic uses thereof
Samumed, Llc
November 23, 2017 - N°20170333409

Provided herein are compounds according to formulas (i) or (ii) and pharmaceutically acceptable salts thereof, and compositions comprising the same, for use in various methods, including treating cancer, abnormal cellular proliferation, angiogenesis, alzheimer's disease, lung disease, osteoarthritis, idiopathic pulmonary fibrosis and neurological conditions/disorders/diseases.
Formulations having anti-inflammatory activity and antimicrobial activity against gram-positive bacteria
Natureza, Inc.
November 23, 2017 - N°20170333379

Novel active compositions having antimicrobial and anti-inflammatory activity are described, the activity provided by an active component prepared in a suspension, the active component being at least a single chain fatty acid having a carbon length of 12, or between 12 and no more than 18. The fatty acid may be esterified and/or ethylated or methylated. As an antimicrobial the active component ...
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