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Proliferation

Proliferation-related patent applications - as published by the U.S. Patent and Trademark Office (USPTO).


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Biodegradable side chain liquid crystal elastomers: smart responsive scaffolds (srs) for tissue regeneration
Kent State University
April 19, 2018 - N°20180105642

Controlled biodegradable smart responsive scaffold (srs) materials enhance attachment and viability of cells, i. E. Actively guiding their expansion, proliferation and in some cases differentiation, while increasing their biomechanical functionality is an important key issue for tissue regeneration. Chemically build-in functionality in these biodegradable srs materials is achieved by varying structural functionalization with biocompatible liquid crystal motifs and general polymer ...
Azo-quaternary pyridinium salts with acid-enhanced antibacterial efficacy, methods of use, methods of synthesis, and uses ...
Ada Foundation
April 19, 2018 - N°20180105495

A new azo-type quaternary pyridinium salt (azo-qps) shows enhanced activity at acidic conditions (e. G., ph=5); in neutral or basic conditions, this new azo-qps shows a much lower level (2-50 times less) anti-bacterial activity. The use of such a “stimulus-enhance” antibiotic can response to the proliferation of bacteria directly. It helps reduce or prevent the build-up ...
N1-cyclic amine-n5-substituted biguanide derivatives, methods of preparing the same and pharmaceutical composition comprising ...
Immunomet Therapeutics Inc.
April 19, 2018 - N°20180105494

The present invention provides an n1-cyclic amine-n5-substituted biguanide derivative compound represented by formula 1, a method of preparing the same and a pharmaceutical composition including the biguanide derivative or the pharmaceutically acceptable salt thereof as an active ingredient. The biguanide derivatives have an effect of inhibiting cancer cell proliferation, cancer metastasis and cancer recurrence by activation of ampk, even ...
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Proliferation Patent Applications
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Proximity-based communication system applied to earthquake detection
Bruce Corporation
April 12, 2018 - N°20180103421

The proliferation of networked, wireless-enabled devices is challenged by the reliance upon password management and user knowledge of privacy and security techniques to maintain control over data that is personal, proprietary or restricted. This disclosure enables a geo-proximity security and privacy system for assuring control and non-repudiation for wireless-enabled devices by relying upon location and trusted network relationships among a ...
Formulation for storage, transportation, and delivery of protein rich conditioned medium
Hope Biosciences, Llc
April 12, 2018 - N°20180100138

A method of creating a protein rich conditioned medium. The method includes culturing mesenchymal stem cells in a container utilizing a first growth medium, allowing a time period for proliferation of the mesenchymal stem cells until a desired level of confluence is achieved in the container, discarding a supernatant from the container, adding a second medium to the container, incubating ...
Prostate-specific membrane antigen binding proteins and related compositions and methods
Aptevo Research And Development Llc
April 12, 2018 - N°20180100021

The present invention relates to mono-specific and multi-specific polypeptide therapeutics that specifically target cells expressing prostate-specific membrane antigen (psma) and are useful for the treatment of prostate cancer (e. G., castrate-resistant prostate cancer), tumor-related angiogenesis or benign prostatic hyperplasia (bph). In one embodiment, the multi-specific poly-peptide therapeutics bind both psma-expressing cells and the t-cell receptor complex on t cells to ...
Proliferation Patent Pack
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Proliferation Patent Applications
Download 113+ Proliferation-related PDFs
For professional research & prior art discovery
inventor
  • 113+ full patent PDF documents of Proliferation-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
Engineered oncolytic viruses containing hyper-binding sites to sequester and suppress activity of oncogenic transcription factors ...
Miami University
April 12, 2018 - N°20180099014

In one or more embodiments, the present invention provides novel artificial, non-naturally-occurring double stranded dna segments (and related methods) capable of acting as decoy binding sites for oncogenic transcription factors and a general method for suppressing aberrant activity of oncogenic transcription factors that promote cancer progression. In various embodiments, the present invention involves the sequestration of targeted oncogenic transcription factors ...
Replication of undifferentiated cells in a weightless environment, uses thereof and facility for such replication ...
Zero Gravity Solutions, Inc.
April 05, 2018 - N°20180094237

Manufacturing processes are described for biological replication of undifferentiated plant and animal cells and tissue in a weightless condition, including those systems used in current stem cell research and development and use of undifferentiated parenchyma in plants. Additionally, methods for adapting plants and animals to survive outside their native environments are described. In particular, undifferentiated cells from plants or animals ...
Anti-prlr antibodies and uses thereof
Regeneron Pharmaceuticals, Inc.
April 05, 2018 - N°20180094066

The present invention provides antibodies that bind to prolactin receptor (prlr) and methods of using the same. According to certain embodiments, the antibodies of the invention bind human prlr with high affinity. In certain embodiments, the invention includes antibodies that bind prlr and block prolactin-mediated cell signaling. In other embodiments, the invention includes antibodies that bind prlr but do not ...
Fusion protein comprising an interleukin 4 and interleukin 10
Umc Utrecht Holding B.v.
April 05, 2018 - N°20180094037

The invention is concerned with a fusion protein comprising interleukin 10 and interleukin 4, a nucleic acid molecule encoding such fusion protein, a vector comprising such nucleic acid molecule, and a host cell comprising such nucleic acid molecule or such vector. The invention further pertains to a method for producing such fusion protein. The fusion protein or a gene therapy vector encoding ...
Isoquinolin-3-yl carboxamides and preparation and use thereof
Samumed, Llc
April 05, 2018 - N°20180093970

Isoquinoline compounds for treating various diseases and pathologies are disclosed. More particularly, the present invention concerns the use of an isoquinoline compound or analogs thereof, in the treatment of disorders characterized by the activation of wnt pathway signaling (e. G., cancer, abnormal cellular proliferation, angiogenesis, fibrotic disorders, bone or cartilage diseases, and osteoarthritis), the modulation of cellular events mediated by ...
System and method for healing and/or disinfecting wounds and burns
Gliese 623b, Llc
April 05, 2018 - N°20180093107

A system for healing and/or disinfecting wounds and burns includes an emitter including one or more blue light sources configured to emit blue light at a therapeutic energy level at a wound or burn area of a human or animal subject and one or more ultraviolet-a (uva) light sources configured to emit uva light at a therapeutic energy level ...
Ionic liquids that sterilize and prevent biofilm formation in skin wound healing devices
Dixie State University
April 05, 2018 - N°20180093011

Compositions for enhancing wound healing are disclosed herein. Also disclosed are methods of making the compositions and methods of using the compositions for the prevention of biofilm formation and for the inhibition of pathogen growth and proliferation.
Proliferation Patent Pack
Download 113+ patent application PDFs
Proliferation Patent Applications
Download 113+ Proliferation-related PDFs
For professional research & prior art discovery
inventor
  • 113+ full patent PDF documents of Proliferation-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
Vigor enhancement via administration of pyrimidine derivatives
University Of Central Florida Research Foundation, Inc.
April 05, 2018 - N°20180092913

Disclosed herein are methods for increasing the overall vigor of a subject, and/or vigor of target tissues of a subject. Exemplified herein is the utilization of pyrimidine derivatives which act to stimulate stem cell proliferation. In addition to increasing vigor, such stem cell proliferation agents (scpa) may be used to enhance and/or improve the outcome of other therapies, ...
Gel composition for treatment of common acne comprising a combination of benzoyl perozide and adapalene ...
Galderma Research & Development
April 05, 2018 - N°20180092872

Dermatological/cosmetic compositions suited for preventing or treating cell differentiation and/or proliferation and/or keratinization disorders, including preventing or treating common acne, comprise, in a physiologically acceptable medium, (i) at least one dispersed retinoid, (ii) dispersed benzoyl peroxide, in free or encapsulated form, and (iii) at least one ph-independent gelling agent, selected from the group consisting of (a) polyacrylamide ...
Methods and compositions for labeling nucleic acids
President And Fellows Of Harvard College
March 29, 2018 - N°20180087091

The present invention relates to methods for the labeling of nucleic acid polymers in vitro and in vivo. In particular, the methods include a [3+2] cycloaddition between a nucleotide analogue incorporated into a nucleic acid polymer and a reagent attached to a label. Such methods do not require fixation and denaturation and therefore can be applied to the labeling of nucleic ...
Mesenchymal stem cells expressing tnf-alpha receptors
Mesoblast International Sárl
March 29, 2018 - N°20180087032

Mesenchymal stem cells which express tnf-α receptor type i in an amount of at least 13 pg/106 cells. Such mesenchymal stem cells inhibit the proliferation of lymphocytes and may be employed, in particular, in the treatment of graft-versus-host disease.
Human igm antibodies, and diagnostic and therapeutic uses thereof particularly in the central nervous system
March 29, 2018 - N°20180086821

Antibodies, particularly human antibodies, are disclosed having activity in treatment of demyelinating diseases and diseases of the central nervous system. Neuromodulatory agents are provided comprising a material selected from the group consisting of an antibody capable of binding structures or cells in the central nervous system, a peptide analog, and active fragments, monomers and combinations thereof having one or more ...
Inhibition of pulmonary fibrosis with nutlin-3a and peptides
Board Of Regents, The University Of Texas System
March 29, 2018 - N°20180086791

In fibrotic lung fibroblasts, basal levels of p53 protein (and mir-34a) are markedly suppressed, leading to reduced p53-mediated inhibition of upa and upar, or concurrent induction of pai-1. These changes contribute to excessive fl-fibroblast proliferation and production of extracellular matrix (ecm), and, therefore, pulmonary fibrosis. These processes are reversed by treating the cells, and treating subjects suffering from ...
Substituted pyrrolo[2,3-d]pyrimidines
Millennium Pharmaceuticals, Inc.
March 29, 2018 - N°20180086785

This invention relates to compounds that inhibit e1 activating enzymes, pharmaceutical compositions comprising the compounds, and methods of using the compounds. The compounds are useful for treating disorders, particularly cell proliferation disorders, including cancers, inflammatory and neurodegenerative disorders; and inflammation associated with infection and cachexia.
3-(1h-benzo[d]imidazol-2-yl)-1h-pyrazolo[3,4-c]pyridine and therapeutic uses thereof
Samumed, Llc
March 29, 2018 - N°20180086754

Azaindazole compounds for treating various diseases and pathologies are disclosed. More particularly, the present invention concerns the use of an azaindazole compound or analogs thereof, in the treatment of disorders characterized by the activation of wnt pathway signaling (e. G., cancer, abnormal cellular proliferation, angiogenesis, fibrotic disorders, bone or cartilage diseases, and osteoarthritis), the modulation of cellular events mediated by ...
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