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Polysaccharide patents

This page is updated frequently with new Polysaccharide-related patent applications. Subscribe to the Polysaccharide RSS feed to automatically get the update: related Polysaccharide RSS feeds. RSS updates for this page: Polysaccharide RSS RSS

Date/App# patent app List of recent Polysaccharide-related patents
 Multivalent meningococcal conjugates and methods for preparing conjugates patent thumbnailnew patent Multivalent meningococcal conjugates and methods for preparing conjugates
Disclosed herein are meningococcal immunogenic conjugates which can elicit immune responses against meningococcal polysaccharides (ps) from groups a, c, w-135, and y and group b factor h binding protein (fhbp). The disclosed conjugates also exhibit bactericidal activity against meningococcal a, c, w-135, y, b, and x serogroups.
Government Of The United States, As Represented By The Secretary Of The Army
 Meningococcus serogroup x conjugate patent thumbnailMeningococcus serogroup x conjugate
The invention provides a conjugate of a neisseria meningitidis serogroup x capsular polysaccharide and a carrier molecule. The conjugate is typically made by (a) oxidising a primary hydroxyl group in the capsular polysaccharide, to give an oxidised polysaccharide with an aldehyde group; and (b) coupling the oxidised polysaccharide to a carrier molecule via the aldehyde group, thereby giving the conjugate.
Novartis Ag
 Compositions comprising fibrous polypeptides and polysaccharides patent thumbnailCompositions comprising fibrous polypeptides and polysaccharides
Isolated polypeptides are disclosed comprising an amino acid sequence encoding a monomer of a fibrous polypeptide attached to a heterologous polysaccharide binding domain. Composites comprising same, methods of generating same and uses thereof are all disclosed..
Collplant Ltd.
 Chimeric multivalent polysaccharide conjugate vaccines patent thumbnailChimeric multivalent polysaccharide conjugate vaccines
The present invention provides multivalent chimeric conjugate vaccine molecule and methods of using the conjugate to immunize subjects against bacterial infections. A conjugate molecule of the invention comprises multiple bacterial capsular polysaccharides linked to a carrier protein.
Baxter Healthcare Sa
 Methods to alter plant cell wall composition for improved biofuel production and silage digestibility patent thumbnailMethods to alter plant cell wall composition for improved biofuel production and silage digestibility
The disclosure provides means for altering the expression of non-cellulosic polysaccharides in plants using golgi targeted enzyme nucleic acids and their encoded proteins. The present disclosure provides methods and compositions relating to altering feruloylation, acetylation and crosslinking in plants, leading to improved biomass available for biofuel production and silage digestibility.
E I Du Pont De Nemours And Company
 Wound dressing containing polysaccharides patent thumbnailWound dressing containing polysaccharides
A wound dressing makes use of polysaccharides, including the formation of a range of variable viscosity mixtures that use a solid polysaccharide such as medical grade cane sugar and a liquid polysaccharide such as honey, both of which have inherent beneficial properties for wound healing. The mixture is applied to an absorbent surface that is designed to absorb the mixed polysaccharide only partially..
Medline Industries, Inc.
 Exopolysaccharide for the treatment and/or care of the skin, mucous membranes and/or nails patent thumbnailExopolysaccharide for the treatment and/or care of the skin, mucous membranes and/or nails
Exopolysaccharide of a bacterial strain for its use in treatment and/or care of the skin, mucous membranes, hair and/or nails, as well as its cosmetic and/or dermopharmaceutical compositions. In particular, for the aging of skin and in particular for the treatment and/or prevention of wrinkles..
Polymaris Biotechnology
 Evoking protection against streptotoccus pneumoniae incorporating b-cell and t-cell pneumococcal protein antigens and pneumococcal polysaccharides delivered concomitantly patent thumbnailEvoking protection against streptotoccus pneumoniae incorporating b-cell and t-cell pneumococcal protein antigens and pneumococcal polysaccharides delivered concomitantly
This disclosure is directed to compositions that combine the polysaccharide-specific antibody protection afforded by the conventional vaccines through carrier effects provided by one or more pneumococcal common t-cell antigen(s) together with streptococcus pneumoniae-specific th-17 responses elicited by the pneumococcal carrier common t-cell antigen. The disclosed compositions are useful for pan-serotypic protection against np carriage, and antibody responses against common pneumococcal virulence factors, potentially useful for pan-serotype protection against streptococcus pneumoniae invasive diseases..
 Vaccine patent thumbnailVaccine
The present invention relates to the field of bacterial polysaccharide antigen vaccines. In particular, the present invention relates to bacterial polysaccharides conjugated to protein d from h.
Glaxosmithkline Biologicals S.a.
 Vaccine patent thumbnailVaccine
The present invention relates to the field of bacterial polysaccharide antigen vaccines. In particular, the present invention relates to bacterial polysaccharides conjugated to protein d from h.
Glaxosmithkline Biologicals S.a.

Process for the preparation of polysaccharide nanoparticles

A process for the preparation of nanoparticles from polysaccharides and derivatives thereof, by their specific partial oxidation to produce aldehyde groups and attachment of compounds with amino or other group with the r—nh2 bond which react with aldehyde groups, and a nanoparticle produced by such process.. .
Nanovelos Sp. Z O.o.

Use of botrytis cinerea for obtaining gold nanoparticles

The present invention is related to the use of botrytis cinerea strains, its spores, hyphae mycelium, sclerotia, intra and/or extracellular organic molecules, such as proteins, nucleic acids, polysaccharides, lipids and secondary metabolites for the biosynthesis of gold nanoparticles (aunps). In general terms, the present invention is focused to use b.
Universidad De Santiago De Chile

Basidiomycetous yeast mutant

The present invention provides a host for genetic recombination useful in the production of heterologous proteins in a large scale, by suppressing the production of extracellular polysaccharides in the basidiomycetous yeasts. Cryptococcus sp.
National Research Institute Of Brewing

Glycoconjugates and use thereof as vaccine against shigella flexneri serotype 3a and x

The present invention relates to compounds derived from sugars which reproduce the epitopes of shigella flexneri serotypes 3a and x and to the use thereof for the preparation of vaccine compositions. More specifically, the subject matter of the present invention relates to novel glycoconjugated compounds comprising oligosaccharides or polysaccharides described hereinafter, to the method for synthesizing these oligosaccharides or polysaccharides and glycoconjugates, to derivatives of these oligosaccharides or polysaccharides, to compositions containing same, and also to the use of the glycoconjugates for vaccination purposes.
Universite Paris Descartes

Fast dissolving pharmaceutical composition

The subject invention is directed to a pharmaceutical composition comprising an open matrix network carrying a pharmaceutically active ingredient, wherein the open matrix network comprises both the polysaccharides levan and inulin.. .
Ferring B.v.

Process for protecting and repairing keratin fibres using anionic oxidized polysaccharides

The present invention relates to a cosmetic treatment process for keratin fibres which have not been artificially coloured, in particular human keratin fibres such as the hair, which consists in using one or more anionic oxidized polysaccharides and in raising the temperature of the keratin fibres.. .

Skin-protecting alkalinity-controlling composition and the use thereof

A skin-protecting alkalinity-controlling composition comprises one or more carboxylic acid polysaccharides. Said compositions are capable of providing buffering, and thus avoiding a major increase in the ph of an aqueous system and/or are capable of reducing the ph of aqueous systems, in which alkalinity is formed as a result of chemical and/or biological reactions.
Cp Kelco Aps

Process for the manufacturing of a drug delivery system based on a polymer comprising a dispersed bioactive agent

Process for the manufacturing of a drug delivery system based on a polymer comprising dispersed bioactive agent via the following process steps: (a) dissolving a polymer in an organic solvent (b) mixing the dissolved polymer with the bioactive agent (c) laminating the mixture between two polymer sheets, whereby at least one of the sheets is permeable to the organic solvent, to provide a film whereby the film can be further processed into the drug delivery system. The drug delivery system is suitable for implantation or injection and comprises fibres, rods, discs, coatings, tubes, films or rolled films.
Dsm Ip Assets B.v.

Novel leech hyaluronidase and its application

The present invention provides a novel leech haase and a method of producing low-molecular-weight ha oligosaccharides using the leech haase. This invention successfully cloned the first leech haase gene and provides a method for high-level expression of the leech haase gene.
Jiangnan University

Reduction of non-starch polysaccharides and alpha-galactosides in soy flour by means of solid-state fermentation using cellulolytic bacteria isolated from different environments

The invention relates to a method for fermenting soy flour in the solid state in order to reduce non-starch polysaccharides and alpha-galactosides, said method comprising the following steps: a) preparation of the fermentation substrate; b) inoculation of the substrate with selected celluloytic bacterial strains; c) incubation; and, optionally, d) drying of the product, which generates a product with: an increase in protein of between 12 and 15% compared to non-fermented soy flour, degradation of the alpha-galactosides of more than 90% compared to non-fermented soy flour, a reduction in non-starch polysaccharides (nsps) of between 15 and 25%, an amino acid profile similar to that of non-fermented soy flour, and immune-stimulating effects.. .
Universidad De Chile

Application of macroporous silica synthesized by a salt-templated aerosol chromatography

The present invention discloses a silica particle having a diameter less than or equal to 2 μη, wherein the particle is spherical and comprises interconnected pores having a diameter in the range from 50 nm to 300 nm. The silica particle is preferably produced by spray pyrolysis (=spray drying) of a silica colloid.
Indiana University Research And Technology Corporation

Gastric reflux resistant dosage forms

Gastric resistant film-forming compositions are described herein. The composition comprises a gastric resistant natural polymer, a film-forming natural polymer, and optionally a gelling agent.
Banner Pharmacaps Inc.

Low-calorie pasta and the production thereof

Repeated attempts have been made to produce low-calorie pasta that has the characteristics of conventional pasta. According to the invention, the aim is achieved using a dough made of durum wheat flour, or oat bran, microcellulose, polysaccharides, oil, an emulsifier and water.

Capsular gram-positive bacteria bioconjugate vaccines

The present invention encompasses a novel s. Aureus bioconjugate vaccine.
Glycovaxyn Ag

Methods and compositions for increasing rna interference

The present invention relates to compositions containing a combination of a first active component comprising one or more sulfated polysaccharides and/or glycosaminoglycans and a second active component comprising one or more rnai-inducing molecules, and methods for using these compositions to enhance double-stranded rna (dsrna)-mediated gene silencing in pest or pathogen species. The invention further relates to methods for controlling pests or pathogens, methods for preventing pest infestations or pathogen infections and methods for knocking down gene expression in pests or pathogens using the compositions and methods of the invention..
Devgen N.v.

Methods for conjugation of oligosaccharides or polysaccharides to protein carriers through oxime linkages via 3-deoxy-d-manno-octulsonic acid

Methods for preparing an oligosaccharide—protein carrier immunogenic conjugate or a polysaccharide—protein carrier immunogenic conjugate. The methods include obtaining an oligosaccharide or polysaccharide having a kdo moiety located at the terminal reducing end of the oligosaccharide or polysaccharide that includes a carbonyl functional group; and reacting the carbonyl functional group of the kdo moiety with an aminooxylated protein carrier molecule resulting in a conjugate that includes a covalent oxime bond between the oligosaccharide and the protein carrier or the polysaccharide and the protein carrier..
National Research Council Of Canada

Dry food product containing live probiotic

The disclosure relates to a probiotic delivery system that can be consumed as a snack-food or added to a food product. In particular, the disclosure describes a crisp and tasty treat that comprises viable probiotic microorganisms preserved in a vacuum dried matrix of sugars, proteins, and polysaccharides.
Advanced Bionutrition Corporation

Immunogenic composition

The invention provides immunogenic polysaccharide protein conjugates comprising capsular polysaccharides from n. Meningitidis serogroup x and methods for preparation thereof.
Serum Institute Of India Ltd.

Process for the production of an intermediate product intended for the production of ethanol and for the production of lignin

A process for producing from a lignocellulosic raw material of (i) an intermediate product that is intended for the production of ethanol, containing polysaccharides, cellulose and hemicelluloses, and (ii) a product containing lignin in an aqueous solution without sulfur residue, this lignin could be precipitated. The process includes a step of pulping the raw material in an extruder at a temperature of between 60° c.
Valagro Carbone Renouvelable Poitou-charentes

Produced water borate crosslinking compositions and use

A composition and method for treating a fracturing fluid comprising produced water with high levels of dissolved solids using a polymer crosslinked with a boron compound and a high ph alkylamine buffer. The composition improves the viscosity stability of the fracturing fluid at elevated bottom-hole temperatures, particularly when the fluid has high levels of calcium and magnesium.

Shortened purification process for the production of capsular streptococcus pneumoniae polysaccharides

A shortened process for producing a solution containing substantially purified capsular polysaccharides from a cellular streptococcus pneumoniae lysate broth is described. Ultrafiltering and diafiltering a clarified s.

Methods for producing melanin and inorganic fertilizer from fermentation leachates

Melanin or inorganic fertilizers are produced from fermentation leachates or from low-cost nutrient-rich solutions. The method for producing the melanin or inorganic fertilizer comprises repetitive trophic cycling in the controlled conditions of primary and secondary bioreactors.

Healing cream

A method for formulating a cationic and non-ionic oil in water emulsion, preferably in a cream form, containing growth factors, preferably platelet derived growth factors, specific matrikine peptides, botanicals, emollients, nano-molecules, antioxidants, antiseptics, neuro-peptides, anti-dermatophytics, polysaccharides, sensorial peptides, osmotically driven moisturizers, and siloxane barriers. For application to the feet and other affected parts of the body for the relief of diabetic skin and tissue trauma..

Composition from lobster hemocyte extracts for detection of lipopolysaccharides, peptidoglycans and 1,3-beta-d-glucans

The present invention relates to the pharmaceutics, biotechnological and chemical, and particularly to a process for preparing a composition for detecting and measuring the concentration of endotoxins or lipopolysaccharides, peptidoglycans and (1,3)-β-d-glucans, using an extract from the hemocytes of the lobster as a starting material, the changes to the composition to increase the sensitivity, and processes for measuring endotoxins, peptidoglycans and (1,3)-β-d-glucans using said composition.. .

Rapid two-step synthesis of anti-coagulants

The present invention provides methods for the production of n-deacetylate n-sulfate derivatives of non-sulfated n-acetyl heparosan (hs) polysaccharides, compounds thus obtained and compositions comprising same. This invention also provides applications of n-deacetylate n-sulfate derivatives of non-sulfated n-acetyl heparosan (hs) polysaccharides, and compositions comprising same, for use in controlling coagulation and treating thrombosis..

Use of bacillus composition for increasing the amount of available sugars in animal feed

Described are methods for assaying whether a bacillus composition comprising at least one bacillus strain is capable of increasing the amount of available sugar from animal feed comprising non-starch polysaccharides (nsp). Also described are methods for increasing the amount of available sugar from animal feed comprising non-starch polysaccharides (nsp), comprising adding to the animal feed a bacillus composition comprising at least one bacillus strain, which compositions produces 120 hexose equivalents (μmol/ml) or more when measured by the method described herein.

Strain of exopolysaccharide-secreting lactobacillus brevis and application thereof

A strain of exopolysaccharide-secreting lactobacillus brevis, bdlb0001, and an application thereof. The lactobacillus brevis is deposited at the china general microbiological culture collection center of the china committee of culture collection for microorganisms, with a deposit number of cgmcc no.

Stabalized glycosaminoglycan preparations and related methods

Compositions comprising a glycosaminoglycan (e.g., a hyaluronan, hyaluronic acid, hyaluronate, sodium hyaluronate, dermatan sulfate, karatan sulfate, chondroitin 6-sulfate, heparin, etc.) in combination with at least one component selected from; i) polyglycols (e.g., polyethylene glycol), ii) long chain hydroxy polyanionic polysaccharides (e.g., dextran, sodium alginate, alginic acid, propylene glycol alginate, carboxymethyl cellulose and carboxyethyl cellulose, hydroxyl ethyl starch, hydroxyl propyl methyl cellulose, hydroxy propyl ethyl cellulose, hydroxy propyl cellulose, methyl cellulose, polylysine, polyhistidine, polyhydroxy proline, poly ornithine, polyvinyl pyrolidone, polyvinyl alcohol, chitosan, etc.) and iii) long chain nitrogen containing polymers (e.g., polylysine, polyvinylpyrrolidone, and polyvinyl alcohol). The invention also includes methods for using such compositions (e.g., as substance delivery materials, tissue fillers or bulking agents, as moistening or hydrating agents, etc.).

Targeted gene deletions for polysaccharide slime formers

The present invention provides improved polysaccharides (e.g., gellan and diutan) produced by mutant gene r, m or n sphingomonas strains containing at least one genetic modification that favors slime-forming polysaccaride production. Methods of making the mutant sphingomonas strains and the culture broth containing such mutant sphingomonas strains are also provided..

Method for preparing polysaccharide of green tea and cosmetic compositon for skin whitening, moisturization and anti-wrinkle effects comprising the polysaccharide

Disclosed is a method for preparing polysaccharides of green tea, and more particularly to a method for preparing polysaccharides of green tea comprising the steps of: a) removing chlorophyll and a low molecular weight polyphenol from green tea powder using a solvent; b) hot-water extracting a water-soluble active ingredient from the green tea residue of step a); and c) separating the polysaccharides of green tea from the hot-water extract of step b) by ultrafiltration and ethanol precipitation. Also, the present invention relates to a cosmetic composition for skin whitening, moisturization and anti-wrinkle effects comprising the polysaccharides of green tea as an effective ingredient..

Super soft foams

Super-soft foam materials, optionally for use as medical dressings, are provided. The pads are made of a foam prepared from nco-terminated prepolymers in combination with an aqueous phase including fatty alcohols and alkyl polysaccharides.

Xylanases for animal feed

The present invention relates to the use in animal feed of a xylanase having a percentage of identity to a paenibacillus xylanase having the sequence of amino acids 1-184 of seq id no: 4 of at least 82.7%, as well as to feed additives and feed compositions comprising such xylanase. These xylanases are significantly better than known animal feed xylanases to solubilize and also degrade insoluble fibre polysaccharides (non-starch polysaccharides, abbreviated nsp), such as arabinoxylan polysaccharides..

Chemical reagents for the activation of polysaccharides in the preparation of conjugate vaccines

This invention provides novel reagents for cyanating polysaccharides in aqueous or part aqueous solutions so that they may be covalently linked to proteins either directly or through a spacer. These reagents include 1-cyano-4-pyrrolidinopyridinium tetrafluoroborate (cppt), 1-cyano-imidazole (1-ci), 1-cyanobenzotriazole (1-cbt), or 2-cyanopyridazine-3(2h)one (2-cpo), or a functional derivative or modification thereof.

Strain of exopolysaccharide-secreting lactobacillus plantarum and application thereof

Provided is a strain of exopolysaccharide-secreting lactobacillus plantarum and an application thereof. The deposit number of the strain is cgmcc no.

Pneumococcal dosing regimen

Methods of immunizing older adult subjects against streptococcus pneumoniae infection are provided. Provided methods comprise immunization of naïve adult subjects with a conjugated pneumococcal polysaccharide vaccine.

Preparation of oligosaccharides containing amine groups

Described are oligo- and polysaccharides containing amine groups. Specifically, described is a new process to manufacture cationic cellulose oligomers.

Chemical reagents for the activation of polysaccharides in the preparation of conjugate vaccines

This invention provides novel reagents for cyanating polysaccharides in aqueous or part aqueous solutions so that they may be covalently linked to proteins either directly or through a spacer. These reagents include 1-cyano-4-pyrrolidinopyridinium tetrafluoroborate (cppt), 1-cyanoimidazole (1-ci), 1-cyanobenzotriazole (1-cbt), or 2-cyanopyridazine-3(2h)one (2-cpo), or a functional derivative or modification thereof.

Chemical reagents for the activation of polysaccharides in the preparation of conjugate vaccines

This invention provides novel reagents for cyanating polysaccharides in aqueous or part aqueous solutions so that they may be covalently linked to proteins either directly or through a spacer. These reagents include 1-cyano-4-pyrrolidinopyridinium tetrafluoroborate (cppt), 1-cyano-imidazole (1-ci), 1-cyanobenzotriazole (1-cbt), or 2-cyanopyridazine-3(2h)one (2-cpo), or a functional derivative or modification thereof.

Antidandruff agent sulfated polysaccharides

The invention relates to the cosmetic use of a sulfated polysaccharide chosen from: dextran sulfate and sulfated polysaccharides derived from the red alga porphyridium sp, as active agent for preventing and/or treating dandruff of the scalp.. .

Andrographis paniculata extract

An extract of andrographis paniculata extract containing androgapholide, 14-deoxyandrographolide, 14-deoxy-11,12-dehydroandrographolide, neoandrographolide, polysaccharides, and flavanoids. Also disclosed is a pharmaceutical composition containing such an extract and its use for treating inflammatory bowel disease..

Treatment of a subterranean formation with composition including a microorganism or compound generated by the same

The present invention relates to methods of treating a subterranean formation with a composition including a compound made by a microorganism or a microorganism that can make the compound. Various embodiments provide methods of using compositions for treatment of subterranean formations including exopolysaccharides or microorganisms that can make exopolysaccharides under downhole conditions.

Polysaccharide ester microspheres and methods and articles relating thereto

A method for producing a polysaccharide ester microsphere may include forming a polysaccharide ester product from a polysaccharide synthesis, wherein the polysaccharide ester product comprises a polysaccharide ester and a solvent; diluting the polysaccharide ester product, thereby yielding a polysaccharide ester dope; and forming a plurality of polysaccharide ester microspheres from the polysaccharide ester dope. Suitable polysaccharides may include, but are not limited to, starch, cellulose, hemicellulose, algenates, chitosan, and any combination thereof.

Method for adding enzymes to obtain high ethanol yield from cereal mash

The present invention generally relates to processes for production of monosaccharides and ethanol from energy crops. In some aspects, the present invention relates to improvements in ethanol production from energy crops including fractionating liquefied mash to generate a fraction enriched in complex polysaccharides such as cellulose, conversion of the cellulosic components to monosaccharides, and preparation of ethanol therefrom..

Method of producing biofuel using sea algae

The present invention relates to a method of producing biofuel, more specifically a method of producing biofuel comprising the steps of generating monosugars from marine algae, or from polysaccharides extracted from marine algae by treating the marine algae or the polysaccharides with a hydrolytic enzyme and/or a hydrolytic catalyst; and fermenting the monosugars using a microorganism to produce biofuel. The method of producing biofuel of the present invention solve the problem of raw material suppliance since it uses marine algae as a raw material for biomass, and reduce the production costs by excluding lignin eliminating process that has been required by the conventional method using wood-based raw materials, resulting in economic and environmental advantages..

Chewing gum base containing substituted polysaccharides and chewing gum products made there from

A chewing gum base comprises food acceptable substituted polysaccharides wherein substituents on the saccharide units in the polysaccharides produce a degree of substitution of at least i.0. The polysaccharides may have branches with an average length of 1 to 15 saccharide units per branch.

Method for extracting polysaccharides from higher plants and fungi through microwave chemical treatment

The present invention has significant advantages like fast processing rate, high polysaccharides yield, low organic acid consumption and efficient and easy to recycle, low water consumption, low power consumption, etc., and obtained polysaccharides have high yield and purity, good water solubility, and good biological activity.. .

Carboxymethylcellulose polyethylene glycol compositions for medical uses

Compositions comprising carboxypolysaccharides (cps) including carboxymethyl cellulose (cmc) and polyethylene glycols (pegs) are provided where the peg is a peg-epoxide covalently linked to the cps. In certain embodiments, the peg attaches to only one cps, forming a decorated cps.

Decreased polysaccharide o-acetylation

The disclosure relates to polypeptides and polynucleotides from multiple species related to the o-acetylation of polysaccharides in plants. The disclosure also describes plants with reduced polysaccharide o-acetylation, methods related to the generation of plants with reduced polysaccharide o-acetylation, polysaccharides with reduced o-acetylation, and methods of using plants and polysaccharides having reduced o-acetylation..

Sensors employing single-walled carbon nanotubes

Sensing compositions, sensing element, sensing systems and sensing devices for the detection and/or quantitation of one or more analytes. Compositions comprising carbon nanotubes in which the carbon nanotubes retain their ability to luminesce and in which that luminescence is rendered selectively sensitive to the presence of an analyte.

Water-soluble soybean polysaccharides and manufacturing process therefor

[solution] the purpose can be achieved by using water-soluble soybean polysaccharides which have a methyl ester content of 30% or below relative to the uronic acids and an acetate content of 1 wt % or higher in terms of free acetic acid and relative to the water-soluble soybean polysaccharides. The water-soluble soybean polysaccharides can be manufactured by subjecting raw material water-soluble soybean polysaccharides to methyl ester removal treatment and thereafter acetate-forming esterification treatment..

Multivalent meningococcal polysaccharide-protein conjugate vaccine

The present invention describes a combined vaccine that offers broad protection against meningococcal disease caused by the pathogenic bacteria neisseria meningitidis. The vaccine is comprised of four distinct polysaccharide-protein conjugates that are formulated as a single dose of vaccine.

Choline-based crosslinker compositions for fracturing fluids

Disclosed are compositions derived of mixtures of choline ion salts (typically choline chloride) in aqueous solution with suspended particulates of sparingly soluble borate minerals or with alkali or alkaline earth borate salts, boric acid and its ester derivatives and salts, or other aqueous soluble borate forms. These compositions are useful as cross-linkers for polysaccharides and other biopolymers and particularly as used in subterranean treatment fluids for completion and stimulation of oil and gas wells.

Methods of producing friction reducing biosynthetic polysaccharides

Methods of treating a subterranean formation including providing a treatment fluid comprising an aqueous base fluid and a friction reducing agent, wherein the friction reducing agent is a biosynthetic polysaccharide produced by a host cell line with dna encoding the biosynthetic polysaccharide; and introducing the treatment fluid into the subterranean formation.. .

Magnetic-nanoparticle conjugates and methods of use

The present invention provides novel compositions of binding moiety-nanoparticle conjugates, aggregates of these conjugates, and novel methods of using these conjugates, and aggregates. The nanoparticles in these conjugates can be magnetic metal oxides, either monodisperse or polydisperse.

Process for manufacturing coated substrates

The present invention relates to a process for manufacturing coated substrates by providing a substrate, providing at least one mineral material, providing a polysaccharide material comprising one or more polysaccharides, coating the substrate with the at least one mineral material, and coating the resulting pre-coat layer of mineral material with the gel comprising one or more polysaccharides, as well as the coated substrate obtained by this process and its use.. .

Method for extracting brown algae polysaccharide via microwave chemical process

This invention relates to an extraction process of brown algae polysaccharides in a field of pharmaceutical chemistry. This invention particularly discloses a process of extracting brown algae polysaccharides based on a microwave chemistry method and brown algae polysaccharides obtained by said process.

Sequential hydrothermal liquifaction (seqhtl) for extraction of superior bio-oil and other organic compounds from oleaginous biomass

Methods of producing bio-fuel and other high-value products from oleaginous biomass (e.g. Algae biomass) are provided.

Compositions and devices for the detection of biomarkers in the gastrointestinal tract and methods for making and using them

In alternative embodiments, the invention provides compositions such as devices, pills, beads, capsules, products of manufacture, particles, microparticles, nanoparticles, gels, liquid gels, liquid gel capsules, capsules, tablets, geltabs, liquids, sprays, emulsions, suspensions, pastes or yogurts, for the detection and isolation of biomarkers, nucleic acids, proteins or peptides, proteoglycans, lipids, fats, sugars or polysaccharides in the gastrointestinal tract for e.g., detecting the presence of particular exogenous or endogenous nucleic acids, e.g., dna or rna, or proteins, in the gastrointestinal tract, for example, to diagnose the presence of an infectious or exogenous agent such as a virus, a fungus, a parasite, a bacteria, intestinal helminths and protozoan parasites, and the like, or a biomarker such as a cancer-causing or cancer-predisposing allele, e.g., mutations of the kras2 oncogene in pancreatic cancer. In alternative embodiments, compositions of the invention comprise magnetic particles such as a magnetically-responsive microparticle or nanoparticle; a superparamagnetic bead or polystyrene bead; a superparamagnetic fine particle; a ferrimagnetic particle; or, a magnetic microsphere, nanosphere, microbead or nanobeads.

Polysaccharide derived materials

A mesoporous material is derived from a polysaccharide by thermally assisted partial carbonisation after expansion. The polysaccharide is an acid containing polysaccharide or mixture of polysaccharides..

Method for the simultaneous production of ethanol and a fermented, solid product

The invention relates to a method for the simultaneous production of a fermented, solid product and ethanol comprising the following steps: 1) providing a mixture of milled or flaked or otherwise disintegrated biomass, comprising oligosaccharides and/or polysaccharides and live yeast in a dry matter ratio of from 2:1 to 100:1, and water; 2) fermenting the mixture resulting from step (1) under conditions where the water content in the initial mixture does not exceed 65% by weight, for 1-36 hours at a temperature of about 25-60° c. Under anaerobic conditions; 3) incubating the fermented mixture resulting from step (2) for 0.5-240 minutes at a temperature of about 70-150° c.; and 4) separating wet fermented, solid product from the fermented mixture resulting from step (3); further comprising either a) that the fermentation in step (2) is performed in one or more interconnected paddle worm or continuous worm conveyers with inlet means for the fermentation mixture and additives and outlet means for the ferment as well as control means for rotation speed, temperature and ph, or b) that one or more processing aids are added in any of steps (1), (2) and (3) and further comprising a step of 5) separating crude ethanol from the fermented mixture in step (2) by vacuum and/or in step (3) by vacuum or by injection of steam and condensing the surplus stripping steam.

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