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Polysaccharide

Polysaccharide-related patent applications - as published by the U.S. Patent and Trademark Office (USPTO).


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Conjugates of carboxy polysaccharides with fibroblast growth factors and variants thereof
Hepacore Ltd.
July 13, 2017 - N°20170196986

Conjugates of hydrophilic carboxy polysaccharides with protein members of the fibroblast growth factor (fgf) family and variants thereof. The conjugates provide a modified bioactivity and stability of fgfs for various therapeutic applications.
Algae-derived antimicrobial plastic substrates, and a method of manufacturing the same
Bloom Holdings, Llc
June 29, 2017 - N°20170183469

This document presents algae-derived antimicrobial plastic substrates, and a method of making the same. The plastic is preferably synthetic, but can also be formed as a bioplastic (e. G., polylactic acid). In various implementations, an algae-derived antimicrobial plastic substrate can be made to have similar properties and characteristics of nylon, nylon-6, nylon 6-6 polymer, and/or the like, and yet ...
Processing of natural polysaccharides by selected non-pathogenic microorganisms and methods of making and using the ...
Mannatech, Incorporated
June 22, 2017 - N°20170173067

The present invention includes compositions and methods of making and using a dietary supplement manufactured from one or more natural polysaccharides previously incubated with a probiotic bacteria in a bioreactor system, wherein the bacteria process the polysaccharides and the resulting processed polysaccharide are provided in the nutritional supplement.
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Methods and compositions for detection of analytes
T2 Biosystems, Inc.
June 08, 2017 - N°20170159113

The present invention relates to methods and compositions for detecting analytes, including proteins, polysaccharides, viruses, nucleic acids and cells. The methods and compositions utilize a reporter probe, suitably a multivalent reporter probe, to detect the presence of the analytes. In embodiments, the methods and compositions can be used for non-enzymatic detection of nucleic acids.
Dissolvable nasal sinus sponge
Medtronic Xomed, Inc.
June 08, 2017 - N°20170157283

An implantable article comprising a dissolvable sponge derived from the mixture of chitosan, a first polysaccharide and a second polysaccharides. The polysaccharides have different number average molecular weight characteristics to enable the control of the mechanical features of the sponge.
Compositions and kits for enzymatic debridement and methods of using the same
Rochal Industries, Llc
June 01, 2017 - N°20170151314

A debridement enzyme for necrotic tissue is described that is not dependent upon proteolytic enzymatic activity but instead utilizes the amylase family of enzymes. The amylases (α-, β-, γ-amylase) are noted for the cleavage of the α-glycosidic bonds of polysaccharides, yielding lower molecular weight carbohydrate/sugar fragments. It has now been found ...
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A pharmaceutical oil-in-water nano-emulsion
Rochal Industries, Llc
May 25, 2017 - N°20170143627

Accordingly, the present invention provides a pharmaceutical oil-in-water nano-emulsion, with a pharmaceutically active substance. The selected pharmaceutically active substance is encased in monounsaturated fatty acid droplets with the droplets having an average particle size in the range of 60 to 200 nm. The nano-emulsion is also provided with a non-ionic surfactant system, which is a mixture of polyethers, macrogolglycerides and polysaccharides, along ...
Algae-derived flexible foam, and a method of manufacturing the same
Rochal Industries, Llc
May 25, 2017 - N°20170142978

This document presents algae-derived antimicrobial fiber substrates, and a method of making the same. The fiber may be a synthetic fiber, but can also be formed as a cellulosic (e. G., cotton). In various implementations, an algae-derived antimicrobial fiber substrate can be made to have identical properties and characteristics of nylon-6 of nylon 6-6 polymer or the like, and yet ...
Antibody molecule-drug conjugates and uses thereof
Visterra, Inc.
May 11, 2017 - N°20170129942

Antibody molecule-drug conjugates (adcs) that specifically bind to lipopolysaccharides (lps) are disclosed. The antibody molecule-drug conjugates can be used to treat, prevent, and/or diagnose bacterial infections and related disorders.
Compacted hemostatic cellulosic aggregates
Ethicon, Inc.
May 11, 2017 - N°20170128618

The present invention is directed to a hemostatic material comprising a compacted, hemostatic aggregates of cellulosic fibers. In some aspects, the hemostatic material further includes additives, such as carboxymethyl cellulose (cmc) or other polysaccharides, calcium salts, anti-infective agents, hemostasis promoting agents, gelatin, collagen, or combinations thereof. In another aspect, the present invention is directed to a method of making the ...
Capsular gram-positive bacteria bioconjugate vaccines
Glycovaxyn Ag
May 11, 2017 - N°20170128559

The present invention encompasses a novel s. Aureus bioconjugate vaccine. More generally, the invention is directed to gram-positive and other bioconjugate vaccines containing a protein carrier, at least one polysaccharide such as a capsular gram-positive polysaccharide, and, optionally, an adjuvant or pharmaceutically acceptable carrier. The instant invention also includes methods of producing gram-positive and other bioconjugate vaccines. An n-glycosylated protein ...
Nanoparticle formulations for delivering multiple therapeutic agents
Amrita Vishwa Vidyapeetham University
May 04, 2017 - N°20170119803

A formulation for treating a patient with hepatocellular carcinoma is disclosed. The formulation comprises therapeutic agents in the form of nanoparticles containing one or more proteins or polysaccharides. The therapeutic agent is conjugated to an active targeting agent causing the formulation to preferentially segregate to the hepatocellular carcinoma tissue to release the therapeutic agents. Methods of treating hepatocellular carcinoma using ...
Carboxylate ester of polysaccharide
Basf Se
April 27, 2017 - N°20170114154

The invention relates to a carboxylate ester of polysaccharide characterised in that it possesses ester bonds with trimellitic anhydride and is soluble in water. The polysaccharide is esterified with trimellitic anhydride and the degree of substitution of the polysaccharide lies in the range of from 0. 5 to 3. The invention further relates to methods for the manufacture of these polysaccharides esters in ...
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Anti-chondroitin-sulfate-e antibody
Seikagaku Corporation
April 20, 2017 - N°20170107301

The present invention provides an antibody that can react with chondroitin sulfate e at a high specificity and that can be used for, for example, the detection, isolation, and so forth, of specific sulfated polysaccharides. The present invention relates to a novel anti-chondroitin sulfate e antibody that reacts with chondroitin sulfate e and does not react with chondroitin sulfate a, ...
Methods for distinguishing and identifying plant varieties
Syngenta Participations Ag
April 13, 2017 - N°20170101663

Methods are disclosed for distinguishing and identifying plants by measuring partial hydrolysis of polysaccharides on account of polysaccharide-hydrolyzing enzyme activity at pre-determined incubation times and temperatures. Methods also are disclosed for identifying the source organism of a heterologous polysaccharide-hydrolyzing enzyme in a plant by measuring partial hydrolysis of polysaccharides on account of polysaccharide-hydrolyzing enzyme activity at pre-determined incubation times and ...
Site-selective modification of polysaccharides and applications thereof
B. G. Negev Technologies And Applications Ltd.
April 06, 2017 - N°20170096500

The present invention relates to site-selective modification of polysaccharides at their reducing end by conjugation with a single aminoxy-regioselective addressable functionalized template (raft) peptide.
Biopolymer extraction
Technische Universiteit Delft
March 30, 2017 - N°20170088637

In a prior art reactor set up dense aggregates of microorganisms are formed, typically in or embedded in an extracellular matrix. Such may relate to granules, to sphere like entities having a higher viscosity than water, globules, a biofilm, etc. The dense aggregates comprise extracellular polymeric substances, or biopolymers, in particular linear polysaccharides. The present invention is in the field ...
Chitin-glucan complex, its preparation, and uses
Pharma73, S.a.
March 23, 2017 - N°20170079917

A biocomposite powder comprising 20-95% (w/w) chitin-glucan complex (cgc), and up to 50% (w/w) mannose-containing polysaccharides, wherein the biocomposite powder has a bulk density of 0. 5 to 1. 0 g/cm3, and wherein greater than 60% (w/w) of the particles of the biocomposite powder have a size below 212 μm.
Purification of secreted polysaccharides from s. agalactiae
Glaxosmithkline Biologicals Sa
March 16, 2017 - N°20170073716

The invention relates to bacterial mutants, particularly from streptococcus agalactiae, that secrete capsular polysaccharide and methods of purifying the secreted bacterial capsular polysaccharides from culture medium. The extracted polysaccharides are useful for producing vaccines comprising the polysaccharides alone or conjugated to proteins.
Cotton fibers with increased glucosamine content
Bayer Cropscience Nv
March 16, 2017 - N°20170073698

An isolated nucleic acid molecule is provided comprising a nucleotide sequence which encodes a glutamine:fructose-6-phosphate amidotransferase from e. Coli which is particularly suitable for expression in cotton plant cells. The invention also relates to plant cells or plants, in particular to cotton plant cells or cotton plants which produce an increased amount of positively charged polysaccharides in their ...
Bacteria and enzymes produced therefrom and methods of using same
Agri-king, Inc.
March 16, 2017 - N°20170073620

A bacteria referred to here as bacillus subtilis 6a-1 is provided, compositions thereof and processes for use of the bacteria, spores, cells, extracts and enzymes. The compositions which comprise the bacteria, spores, cells, extracts and/or enzymes are capable of degrading polysaccharides. Such compositions are capable of degrading cellulose, including plant-produced cellulose, microcrystalline cellulose and carboxymethyl cellulose. The bacteria produces ...
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