FreshPatents.com Logo
Enter keywords:  

Track companies' patents here: Public Companies RSS Feeds | RSS Feed Home Page
Popular terms

[SEARCH]

Follow us on Twitter
twitter icon@FreshPatents

Web & Computing
Cloud Computing
Ecommerce
Search patents
Smartphone patents
Social Media patents
Video patents
Website patents
Web Server
Android patents
Copyright patents
Database patents
Programming patents
Wearable Computing
Webcam patents

Web Companies
Apple patents
Google patents
Adobe patents
Ebay patents
Oracle patents
Yahoo patents

[SEARCH]

Polypeptide patents



      
           
This page is updated frequently with new Polypeptide-related patent applications. Subscribe to the Polypeptide RSS feed to automatically get the update: related Polypeptide RSS feeds. RSS updates for this page: Polypeptide RSS RSS


Date/App# patent app List of recent Polypeptide-related patents
08/14/14
20140230098
 Polypeptides having endoglucanase activity and polynucleotides encoding same patent thumbnailPolypeptides having endoglucanase activity and polynucleotides encoding same
The present invention relates to isolated polypeptides having endoglucanase activity and polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides..
08/14/14
20140230097
 Polypeptides having xylanase activity and polynucleotides encoding same patent thumbnailPolypeptides having xylanase activity and polynucleotides encoding same
The present invention relates to isolated polypeptides having xylanase activity and polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides..
08/14/14
20140230096
 Polypeptides having cellobiohydrolase activity and polynucleotides encoding same patent thumbnailPolypeptides having cellobiohydrolase activity and polynucleotides encoding same
The present invention relates to isolated polypeptides having cellobiohydrolase activity and polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides..
08/14/14
20140230094
 Yield increase in plants overexpressing the shsrp genes patent thumbnailYield increase in plants overexpressing the shsrp genes
A transgenic crop plant transformed by a serine hydroxymethyltransferase-like stress-related polypeptide (shsrp) coding nucleic acid, wherein expression of the nucleic acid sequence in the crop plant results in the plant's increased root growth, and/or increased yield, and/or increased tolerance to environmental stress as compared to a wild type variety of the plant. Also provided are agricultural products, including seeds, produced by the transgenic crop plants.
08/14/14
20140230081
 Polynucleotide, polypeptide, animal model and method for the development of complement system modulators patent thumbnailPolynucleotide, polypeptide, animal model and method for the development of complement system modulators
The present invention is in the field of molecular biology, more particularly, the present invention relates to nucleic acid sequences and amino acid sequences of a hamster c5ar1 and the use of hamster as an animal model for the characterization of complement system modulators within drug discovery.. .
08/14/14
20140228548
 Viral clearance methods patent thumbnailViral clearance methods
The invention provides methods for separating a polypeptide of interest (such as an antibody) from a virus. In some embodiments, the methods involve eluting the polypeptide of interest from a protein a resin with an elution buffer have a particular range of conductivity values that minimizes the amount of virus that co-elutes with the polypeptide of interest..
08/14/14
20140228546
 Serum albumin binding proteins patent thumbnailSerum albumin binding proteins
The present invention relates to amino acid sequences that are capable of binding to serum albumin; to proteins and polypeptides comprising or essentially consisting of such amino acid sequences; to nucleic acids that encode such amino acid sequences, proteins or polypeptides; to compositions, and in particular pharmaceutical compositions, that comprise such amino acid sequences, proteins and polypeptides; and to uses of such amino acid sequences, proteins and polypeptides.. .
08/14/14
20140228544
 Constructs and libraries comprising antibody surrogate light chain sequences patent thumbnailConstructs and libraries comprising antibody surrogate light chain sequences
The invention concerns constructs and libraries comprising antibody surrogate light chain sequences. In particular, the invention concerns constructs comprising vpreb sequences, optionally partnered with another polypeptide, such as, for example, antibody heavy chain variable domain sequences, and libraries containing the same..
08/14/14
20140228540
 Polypeptides that bind tissue inhibitor of metalloproteinase type three (timp-3), compositions and methods patent thumbnailPolypeptides that bind tissue inhibitor of metalloproteinase type three (timp-3), compositions and methods
The present invention relates to timp-3 binding compositions, methods of producing such compositions, and methods of using such compositions, including in the treatment of various conditions.. .
08/14/14
20140228294
 Natriuretic polypeptides with unique pharmacologic profiles patent thumbnailNatriuretic polypeptides with unique pharmacologic profiles
This document provides natriuretic polypeptides. For example, this document provides polypeptides having a natriuretic activity.
08/14/14
20140228288
Pharmaceutical compositions
The present invention provides pharmaceutical compositions comprising at least one polypeptide having glp-1 activity wherein an effective dose of said pharmaceutical composition comprises 15 mg, 30 mg, 50 mg or 100 mg of said polypeptide having glp-1 activity. Also provided are methods of administering the pharmaceutical compositions of the invention..
08/14/14
20140228284
Pharmaceutical compositions
The present invention provides pharmaceutical compositions comprising at least one polypeptide having glp-1 activity wherein an effective dose of said pharmaceutical composition comprises 15 mg, 30 mg, 50 mg or 100 mg of said polypeptide having glp-1 activity. Also provided are methods of administering the pharmaceutical compositions of the invention..
08/14/14
20140228238
Genes and polypeptides relating to breast cancers
The present application provides novel human genes a7322, whose expression is markedly elevated in breast cancer. The present application also provides human genes f3374 whose expression is markedly elevated in breast cancer.
08/14/14
20140227799
Method for measuring anti-wt1 antibody
Provided is an invention relating to a method for measuring an anti-wt1 antibody in a sample allowing measurement and evaluation of the anti-wt1 antibody with higher accuracy and to use of the method. The method for measuring an anti-wt1 antibody in a sample includes using a polypeptide having antigenicity to the anti-wt1 antibody selected from a polypeptide comprising the amino acid sequence of positions 294-449 in seq id no: 1, a partial polypeptide of the polypeptide, and a polypeptide including an amino acid sequence having deletion, substitution, or addition of one to several amino acids in the amino acid sequence constituting each of these polypeptides and/or a polypeptide having antigenicity to the anti-wt1 antibody selected from a polypeptide comprising the amino acid sequence of positions 181-324 in seq id no: 1, a partial polypeptide of the polypeptide, and a polypeptide including an amino acid sequence having deletion, substitution, or addition of one to several amino acids in the amino acid sequence constituting each of these polypeptides..
08/14/14
20140227788
Thermophilic and thermoacidophilic metabolism genes and enzymes from alicyclobacillus acidocaldarius and related organisms, methods
Isolated and/or purified polypeptides and nucleic acid sequences encoding polypeptides from alicyclobacillus acidocaldarius are provided. Further provided are methods for modulating or altering metabolism in a cell using isolated and/or purified polypeptides and nucleic acid sequences from alicyclobacillus acidocaldarius..
08/14/14
20140227765
Compositions and methods related to viruses of the genus negevirus
Certain embodiments are directed to negevirus and their polynucleotides and polypeptides.. .
08/14/14
20140227763
Polypeptides having cellobiohydrolase activity and polynucleotides encoding same
The present invention relates to isolated polypeptides having cellobiohydrolase activity and polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides..
08/14/14
20140227761
Polypeptides having xylanase activity and polynucleotides encoding same
The present invention relates to isolated polypeptides having xylanase activity and polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides..
08/14/14
20140227760
Polypeptides having xylanase activity and polynucleotides encoding same
The present invention relates to isolated polypeptides having xylanase activity and polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides..
08/14/14
20140227759
Oplophorus-derived luciferases, novel coelenterazine substrates, and methods of use
An isolated polynucleotide encoding a modified luciferase polypeptide and substrates. The ogluc variant polypeptide has at least 60% amino acid sequence identity to seq id no: 1 and at least one amino acid substitution at a position corresponding to an amino acid in seq id no: 1.
08/14/14
20140227739
Polypeptides having endoglucanase activity and polynucleotides encoding same
The present invention relates to isolated polypeptides having endoglucanase activity and polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides..
08/14/14
20140227738
Polypeptides having protease activity and polynucleotides encoding same
The present invention relates to isolated polypeptides having protease activity, and polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides..
08/14/14
20140227727
Unconventional protein secretion
The present invention relates to an expression cassette comprising a nucleotide sequence encoding an amino acid sequence, a fragment or variant thereof which directs unconventional protein secretion and a nucleotide sequence encoding a protein of interest. Also contemplated is a vector which comprises the expression cassette, host cells comprising the vectors as well as methods and uses for the production of a polypeptide of interest..
08/14/14
20140227708
Methods and kits used in identifying microrna targets
Described herein are methods and kits used to identify an endogenously expressed target mrna of a microrna of interest. The method involves the use of a dominant negative gw182 polypeptide that forms a stable complex with the target mrna.
08/14/14
20140227391
Polypeptides having alpha-glucosidase activity and polynucleotides encoding same
The present invention relates to isolated polypeptides having alpha-glucosidase activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods for producing and using the polypeptides..
08/14/14
20140227346
Immunogenic combination compositions and uses thereof
This invention generally relates to immunogenic compositions that comprise an rna component and a polypeptide component. Immunogenic compositions that deliver antigens in two different forms—a first antigen from a pathogen, in rna-coded form; and a second antigen from a different pathogen, in polypeptide form—are effective in inducing immune response to both pathogens..
08/14/14
20140227313
Group a streptococcal m-related proteins and methods of use
Immunogenic group a streptococcus m-related polypeptides and peptides and immunogenic compositions comprising these m-related polypeptides and peptides are provided herein that evoke cross-opsonic and cross-protective anti-gas and anti-sdse antibodies in animals. Also provided are preparations comprising immunogenic compositions that comprise m-related polypeptides, peptides, or fusion proteins and that further comprise at least one additional group a streptococcus immunogen, such as an m peptide or spa peptide..
08/14/14
20140227312
A1 moiety of cholera toxin a subunit as an adjuvant for mucosal and systemic vaccines
The present invention relates to cholera toxin cta1 protein fragments, adjuvant compositions, and methods relating to adjuvants for vaccines. The invention also relates to using recombinant cta1 fragments conjugated to a polypeptide containing a protein transduction domain or cell-penetrating peptide as an immunomodulator..
08/14/14
20140227308
Recombinant protein carrying human papillomavirus epitopes inserted in an adenylate cyclase protein or fragment thereof therapeutic uses thereof
The invention relates to a recombinant protein comprising one or several polypeptides bearing one or several epitopes of one or several hpv antigens, said polypeptides being inserted in the same or different permissive sites of an adenylate cyclase (cyaa) protein or of a fragment thereof, wherein said cyaa fragment retains the property of said adenylate cyclase protein to target antigen presenting cells. It also concerns polynucleotides encoding the same.
08/14/14
20140227306
Multimeric multiepitope polypeptides in improved seasonal and pandemic influenza vaccines
The present invention relates to use of multimeric multi-epitope peptide-based compositions for immunizing subjects against influenza by administering the compositions to the subject prior to or together with seasonal or pandemic influenza vaccines. The present invention also relates to compositions that include a multimeric multi-epitope polypeptide and a seasonal or pandemic preparation against influenza..
08/14/14
20140227305
Epstein-barr-virus vaccine
The present invention relates to a vaccine comprising a particle, said particle comprising (i) at least one epstein-barr virus (ebv) structural polypeptide, (ii) at least one ebv lytic polypeptide, (iii) membrane lipids, said particle being devoid of ebv dna, wherein (a) the b-cell transformation capacity of one or more ebv polypeptides required for b-cell transformation as comprised in said particle is disabled while their immunogenicity is maintained; and/or (b) said particle is devoid of one or more ebv polypeptides required for b-cell transformation. Furthermore, the invention relates to a method for generating a particle, to a cell obtained in the method of the invention, a kit comprising the vaccine or the particle generated according to the method of the invention.
08/14/14
20140227301
Immunogenic compositions against human progastrin peptides
Immunogens against human extended-progastrin species comprise (a) a mimetic peptide comprised of (i) the amino acid sequence of a progastrin or a n- and/or c-terminal processed species of a progastrin joined to (ii) a 7 amino-acid spacer coupled to (b) an immunogenic carrier. Illustrative of the mimetic peptide/spacer combination are a 21 amino-acid peptide (seq id no.: 1) and other, related polypeptides (seq id nos.: 2-5).
08/14/14
20140227293
Method for controlling tumor growth, angiogenesis and metastasis using immunoglobulin containing and proline rich receptor-1 (igpr-1)
The present invention provides methods and compositions for the treatment and prevention of angiogenesis, or cancer, e.g., metastatic cancer by administering an effective amount of an inhibitor of immunoglobulin containing proline rich receptor-1 (igpr-1) protein or expression. In particular, the present invention provides methods and compositions for the treatment and prevention of cancer by administering an effective amount of an inhibitor of immunoglobulin containing proline rich receptor-1 (igpr-1) protein or expression which is a soluble extracellular domain igpr-1.
08/14/14
20140227270
Bispecific anti-cxcr7 immunoglobulin single variable domains
The present invention relates to particular polypeptides, nucleic acids encoding such polypeptides; to methods for preparing such polypeptides; to host cells expressing or capable of expressing such polypeptides; to compositions and in particular to pharmaceutical compositions that comprise such polypeptides, for prophylactic, therapeutic or diagnostic purposes. In particular, the present invention provides immunoglobulin single variable domains inhibiting cxcr7 mediated tumour growth..
08/14/14
20140227267
Bovine fusion antibodies
Disclosed herein are immunoglobulin constructs comprising at least one immunoglobulin domain or fragment thereof; and a therapeutic polypeptide or derivative or variant thereof attached to or inserted into said immunoglobulin domain. Also provided are immunoglobulin constructs comprising a mammalian immunoglobulin heavy chain comprising at least a portion of a knob domain in the complementarity-determining region 3 (cdr3h) or fragment thereof; and a therapeutic polypeptide attached to or inserted into said knob domain of the cdr3h.
08/14/14
20140227266
Nogo receptor antagonists
Disclosed are immunogenic nogo receptor-1 polypeptides, nogo receptor-1 antibodies, antigen-binding fragments thereof, soluble nogo receptors and fusion proteins thereof and nucleic acids encoding the same. Also disclosed are nogo receptor antagonist polynucleotides.
08/14/14
20140227263
Use of fgfr1 extra cellular domain proteins to treat cancers characterized by ligand-dependent activating mutations in fgfr2
The present invention relates to the use of fibroblast growth factor receptor i (fgfr1) extracellular domain (ecd) polypeptides for treatment of cancers characterized by ligand dependent activating mutations in fibroblast growth factor receptor 2 (fgfr2). For example, the present invention relates to the treatment of endometrial cancers and other cancers wherein tumor cells express fgfr2 mutants in the igii-igiii hinge region or igiii domain of the protein, such as at amino acid positions 252 and/or 253..
08/14/14
20140227254
Antagonists of bmp9, bmp10, alk1 and other alk1 ligands, and uses thereof
In certain aspects, the present disclosure relates to the insight that a polypeptide comprising a ligand-binding portion of the extracellular domain of activin-like kinase i (alk1) polypeptide may be used to inhibit angiogenesis in vivo, particularly in mammals suffering angiogenesis-related disorders. In certain aspects, the disclosure demonstrates that antagonists of bmp9 and/or bmp10, ligands for alk1, may also be used to inhibit angiogenesis in vivo..
08/14/14
20140224655
Electroblot transfer buffer
A semi-dry, one step electroblot transfer buffer composition for rapid transfer of proteins or polypeptides from polyacrylamide gel to a suitable membrane such as nitrocellulose or polyvinylidene difluoride (pvdf). The composition contains components that minimized electrical resistance and enabled high efficiency rapid semi-dry transfer using conventional readily available filter paper, i.e., cotton cellulose fiber..
08/07/14
20140223609
Protein mixtures for maize insect control
Embodiments of the present invention relate to insecticidal bacillus thuringiensis cry1 and cry2 polypeptides. Methods for using the polypeptides and nucleic acids of embodiments of the invention to synergistically enhance resistance of plants to insect predation are encompassed in embodiments of the present invention..
08/07/14
20140223608
Polypeptides having cellulolytic enhancing activity and polynucleotides encoding same
The present invention provides isolated polypeptides having cellulolytic enhancing activity and polynucleotides encoding the polypeptides. The invention also provides nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides..
08/07/14
20140223606
Compositions and methods comprising sequences having meganuclease activity
Compositions and methods comprising polynucleotides and polypeptides having meganuclease activity are provided. Further provided are nucleic acid constructs, yeast, plants, plant cells, explants, seeds and grain having the meganuclease sequences.
08/07/14
20140223605
Plants with increased yield
This invention relates generally to a plant cell with enhanced nitrogen use efficiency and/or increased biomass production as compared to a corresponding non-transformed wild type plant cell by increasing or generating one or more activities of polypeptides associated with enhanced nitrogen use efficiency in plants.. .
08/07/14
20140223602
Enzymes for the treatment of lignocellulosics, nucleic acids encoding them and methods for making and using them
The invention provides polypeptides having a lignocellulolytic activity, e.g., a glycosyl hydrolase, a cellulase, an endoglucanase, a cellobiohydrolase, a beta-glucosidase, a xylanase, a mannanse, a xylosidase (e.g., a β-xylosidase), an arabinofuranosidase, and/or a glucose oxidase activity, polynucleotides encoding these polypeptides, and methods of making and using these polynucleotides and polypeptides. In one aspect, the invention provides polypeptides that can enzymatically process (hydrolyze) sugarcane bagasse, i.e., for sugarcane bagasse degradation, or for biomass processing, and polynucleotides encoding these enzymes, and making and using these polynucleotides and polypeptides.
08/07/14
20140223599
Axmi279 pesticidal gene and methods for its use
Compositions and methods for conferring pesticidal activity to bacteria, plants, plant cells, tissues and seeds are provided. Compositions comprising a coding sequence for pesticidal polypeptides are provided.
08/07/14
20140223598
Axmi270 toxin gene and methods of use
Compositions and methods for conferring pesticidal activity to bacteria, plants, plant cells, tissues and seeds are provided. Compositions comprising a coding sequence for a toxin polypeptide are provided.
08/07/14
20140223595
Drought tolerant plants and related constructs and methods involving genes encoding dtp6 polypeptides
Isolated polynucleotides and polypeptides and recombinant dna constructs useful for conferring drought tolerance, compositions (such as plants or seeds) comprising these recombinant dna constructs, and methods utilizing these recombinant dna constructs. The recombinant dna construct comprises a polynucleotide operably linked to a promoter that is functional in a plant, wherein said polynucleotide encodes a dtp6 polypeptide..
08/07/14
20140223590
Oplophorus-derived luciferases, novel coelenterazine substrates, and methods of use
An isolated polynucleotide encoding a modified luciferase polypeptide and substrates. The ogluc variant polypeptide has at least 60% amino acid sequence identity to seq id no: 1 and at least one amino acid substitution at a position corresponding to an amino acid in seq id no: 1.
08/07/14
20140223588
A2m fragments and applications thereof
The application relates to a polypeptide, the amino acid sequence of which is the sequence of a sub-fragment of the c-terminal thioester-cleaved fragment of human alpha-2-macroglobulin (a2m), wherein the molecular weight of said polypeptide is of 36 to 44 kda, and wherein the first n-terminal amino acid of said polypeptide is an amino acid, which, in the full length sequence of said human a2m, is at a position 1,098 or 1,085 or 1,084 or 1,083, and the last c-terminal amino acid of said polypeptide is an amino acid, which, in the full length sequence of said human a2m, is one of the last twenty c-terminal amino acids. This polypeptide is differently abundant depending on the stage of liver fibrosis.
08/07/14
20140222348
Mass spectrometry
The present invention is concerned with methods for the de novo sequencing of polypeptides from data obtained from mass spectrometry devices, particularly from (ms)n devices.. .
08/07/14
20140221623
Interleukin-6 receptor binding polypeptides
The invention relates to amino acid sequences that are directed against and/or that can specifically bind to il-6 receptor, compounds or constructs that comprise said amino acid sequence, nucleic acids that encode said amino acid sequences, compounds or constructs, pharmaceutical compositions comprising said amino acid sequences, compounds or constructs as well as methods for the prevention and/or treatment of diseases and disorders associated with il-6 receptor.. .
08/07/14
20140221611
Binding molecules for human factor viii and factor viii-like proteins
It is an object of the present invention to provide novel binding molecules for factor viii and factor viii-like proteins. Preferred binding molecules of the present invention exhibit not only distinct characteristics for binding of the target factor viii polypeptides but also specific and desirable characteristics for release (elution) of the target polypeptides.
08/07/14
20140221607
Monoclonal antibody and antigens for diagnosing and treating lung disease and injury
The present invention provides methods for diagnosing a patient with emphysema, copd of lung injury caused by tobacco use by detecting the levels of emap ii in a sample. Disclosed herein are the hypervariable regions for a rat monoclonal antibody that binds to a form of emap ii.
08/07/14
20140221460
Method for identifying modulators of hcv translation or replication involving the ns5b polypeptide and a pseudoknot
The invention relates to a method for identifying compounds that act as modulators of hepatitis c (hcv) translation and/or replication, and to compounds identified by this method, and their uses in medicine. The invention also relates to an rna useful for identifying modulators of hcv translation and/or replication.
08/07/14
20140221287
Amylin peptides and derivatives and uses thereof
There are provided polypeptide conjugates having enhanced duration of biological activity, and methods of use thereof. The polypeptide conjugates include duration enhancing moieties, including water soluble polymers, bound to the polypeptide components of defined sequence.
08/07/14
20140221271
Shk-based pharmaceutical compositions and methods of manufacturing and using the same
Disclosed herein are pharmaceutical compositions having the sequence arg-ser-cys-ile-asp-thr-ile-pro-lys-ser-arg-cys-thr-ala-phe-gln-cys-lys-his-ser-xaa-lys-tyr-arg-leu-ser-phe-cys-arg-lys-thr-cys-gly-thr-cys (seq id no: 1). The disclosed compositions can include an acid or amide at the c-terminus of seq id no: 1 and the polypeptide can be attached to an organic or inorganic chemical entity that has an anionic charge.
08/07/14
20140221252
Detecting neoplasm
This document relates to methods and materials for detecting premalignant and malignant neoplasms. For example, methods and materials for determining whether or not a stool sample from a mammal contains nucleic acid markers or polypeptide markers of a neoplasm are provided..
08/07/14
20140221248
Kits and methods for generating 5' capped rna
The present invention relates to kits and methods for efficiently generating 5′ capped rna having a modified cap nucleotide and for use of such modified-nucleotide-capped rna molecules. In particular, the present invention provides kits and methods for capping rna using a modified cap nucleotide and a capping enzyme system, such as poxvirus capping enzyme.
08/07/14
20140220674
System for expression of genes in plants
The present invention provides trans-complementation systems for expressing gene products in plants. In general, the invention provides systems including a carrier vector and a producer vector, both based on plant viruses.
08/07/14
20140220661
Live bacterial vaccines for prophylaxis or treatment of infection
A live bacterium, having a dna construct stabilized against transduction of other bacteria, having a promoter sequence and encoding a fusion peptide, comprising a bacterial secretion peptide portion and a non-bacterial immunogenic polypeptide portion, having a nucleotide sequence coding for the non-bacterial immunogenic polypeptide portion which has at least one codon optimized for bacterial expression. The bacterium has a secretion mechanism which interacts with at least the bacterial secretion peptide portion to cause a secretion of the fusion peptide from the bacterium, and a genetic virulence attenuating mutation.
08/07/14
20140220658
Recombinant butyrylcholinesterases and truncates thereof
Isolated nucleic acids encoding polypeptides that exhibit butyrylcholinesterase (bche) enzyme activity are disclosed, along with molecular criteria for preparing such nucleic acids, including codon optimization. Methods of preparing modified and/or truncated bche molecules having selected properties, especially selective formation of monomers, are also described.
08/07/14
20140220656
Constructs and methods for the production and secretion of polypeptides
Described herein are molecules, constructs and methods for the production and secretion of polypeptides of interest by host cells, preferably bacterial host cells, and more particularly gram positive bacteria. In particular, the present invention is related to a polynucleic acid encoding a fusion protein and to uses thereof for the secretion of heterologous or homologous polypeptides of interest by a bacterial host cell, preferably clostridium bacteria.
08/07/14
20140220642
Polypeptides having xylanase activity and polynucleotides encoding same
The present invention provides isolated polypeptides having xylanase activity and polynucleotides encoding the polypeptides. The invention also provides nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides..
08/07/14
20140220636
Phage &phgr;mru polynucleotides and polypeptides and uses thereof
The invention encompasses phage φmru including phage induction, phage particles, and the phage genome. Also encompassed are phage polypeptides, as well as polynucleotides which encode these polypeptides, expression vectors comprising these polynucleotides, and host cells comprising these vectors.
08/07/14
20140220634
Antibodies binding human collagen ii
The present invention relates to antibodies against human collagen ii, polypeptides and polynucleotides encoding human collagen ii antibodies or fragments thereof, and methods of making and using the foregoing.. .
08/07/14
20140220633
Purification of not-glycosylated polypeptides
The current invention reports a method for the purification of a not-glycosylated, heterologous polypeptide, which has been recombinantly produced in a prokaryotic cell, wherein the method comprises three chromatography steps of which the first chromatography step selected from i) hydrophobic charge induction chromatography, or ii) hydrophobic interaction chromatography, or iii) affinity chromatography, or iv) ion exchange chromatography, the second chromatography step is selected from i) anion exchange chromatography, or ii) cation exchange chromatography, or iii) hydroxylapatite chromatography, or iv) hydrophobic interaction chromatography, and the a third chromatography step is selected from i) hydrophobic charge induction chromatography, or ii) anion exchange chromatography, or iii) cation exchange chromatography, or iv) hydrophobic interaction chromatography, whereby the first chromatography step is an affinity chromatography in case of polypeptides capable of interacting with metal ligands, the second chromatography step is not a hydroxylapatite chromatography step in case of polypeptides with an isoelectric point below 6.0, and the third chromatography step can be performed in flow-through mode with polypeptides having a low or high isoelectric point.. .
08/07/14
20140220632
Engineered sequences to facilitate expression of antigens in neisseria and methods of use
The present disclosure generally provides non-naturally-occurring polynucleotide sequences that facilitate high-level expression of one or more gene products (e.g., polypeptides, rna) of interest in neisseria meningitidis. Methods of use of such sequences, e.g., use in vaccine production, are also provided..
08/07/14
20140220629
Novel branchiostoma derived fluorescent proteins
The present invention provides compositions, combinations, methods, sequences and kits for use of novel fluorescent proteins derived from the genus branchiostoma. Specifically, polynucleotide and polypeptide sequences encoding fluorescent proteins isolated from branchiostoma floridae, including harmonized sequences, which permit enhanced expression of the encoded polypeptides in mammalian cells in vivo are provided..
08/07/14
20140220605
Vmp-like sequences of pathogenic borrelia species and strains
The present invention relates to dna sequences encoding vmp-like polypeptides of pathogenic borrelia, the use of the dna sequences in recombinant vectors to express polypeptides, the encoded amino acid sequences, application of the dna and amino acid sequences to the production of polypeptides as antigens for immunoprophylaxis, immunotherapy, and immunodiagnosis. Also disclosed are the use of the nucleic acid sequences as probes or primers for the detection of organisms causing lyme disease, relapsing fever, or related disorders, and kits designed to facilitate methods of using the described polypeptides, dna segments and antibodies..
08/07/14
20140220602
Vaccinia virus polypeptides
This document provides methods and materials related to polypeptides present in a vaccinia virus (e.g., polypeptides that can be isolated from naturally processed and presented class i polypeptides originating from vaccinia virus, a member of the orthopoxvirus family). For example, methods for generating a vaccine comprising one or more of vaccinia virus polypeptides disclosed herein for preventing or treating orthopoxvirus infection are provided.
08/07/14
20140220163
Powder mixture composition of natural materials for controlling deficiencies in polypeptide alpha and beta hemoglobin chains
The embodiments herein provide a powdered composition of natural substances for controlling deficiencies in polypeptide alpha and beta hemoglobin chains and a diet plan for treating thalassemia patient. The composition comprises passargad powder, pars powder, purgative material, fumigation material, snuffing material, vinegar syrup and parsomash powder.
08/07/14
20140220117
Cytotoxic t lymphocyte inducing immunogens for prevention treatment and diagnosis of cancer
The present invention relates to compositions and methods for the prevention, treatment, and diagnosis of cancer, especially carcinomas, such as pancreatic carcinoma. The invention discloses peptides, polypeptides, and polynucleotides that can be used to stimulate a ctl response against pancreatic and other cancers..
08/07/14
20140220066
Group a streptococcus multivalent vaccine
Immunogenic compositions are provided herein that are useful for inducing an immune response specific against group a streptococcus (gas). Immunogenic compositions provided herein are multivalent and comprise a plurality of immunogenic peptides or fusion polypeptides comprising the immunogenic peptides that induce an immune response against gas.
08/07/14
20140220060
Hiv-1 south african subtype c env proteins
The present invention relates to polynucleotides encoding immunogenic hiv polypeptides. Uses of the polypeptides in applications including immunization, generation of packaging cell lines, and production of hiv polypeptides are also described.
08/07/14
20140220051
Methods of modulating hvem, btla and cd160 cis complex response or signaling activity with soluble light polypeptide sequences
The invention provides hvem cis complexes which include, for example, hvem/btla, hvem/cd160 and hvem/gd cis complexes. The invention provides ligands and agents that bind to hvem cis complexes, such as antibodies.
08/07/14
20140220028
Antibodies directed against signal peptides, methods and uses thereof
Provided are methods employing antibodies directed against the signal peptide (sp) domain of various disease-associated polypeptides. These anti-sp antibodies detect cell surface expression of these sp domains and are used in methods of diagnosis and/or therapy.
08/07/14
20140220025
Novel stip1 polypeptides and uses thereof
The present invention is directed toward pharmaceutical compositions comprising an isolated polypeptide and a pharmaceutically acceptable carrier. The present invention also discloses an antibody or an antigen-binding portion thereof that bind to the isolated polypeptide.
08/07/14
20140220012
Novel vista-ig constructs and the use of vista-ig for treatment of autoimmune, allergic and inflammatory disorders
The present invention relates to a fusion proteins comprising regulatory t cell protein, vista (v-domain immunoglobulin suppressor of t cell activation (pd-l3) and an immunoglobulin protein (ig), preferably also containing a flexible linker intervening the vista and ig fc polypeptide. The invention also provides the use of vista polypeptides, multimeric vista polypeptides, vista-conjugates (e.g., vista-ig), and vista antagonists for the treatment of autoimmune disease, allergy, and inflammatory conditions, especially lupus, multiple sclerosis, psoriasis, psoriatic arthritis, multiple sclerosis, crohn's disease, inflammatory bowel disease and type 1 or type 2 diabetes..
08/07/14
20140220011
Polypeptides and polynucleotides, and uses thereof as a drug target for producing drugs and biologics
This invention relates to a novel target for production of immune and non-immune based therapeutics and for disease diagnosis. More particularly, the invention provides therapeutic antibodies against vsig1, ildr1, loc253012, ai216611, clorf32 or fxyd3 antigens, which are predicted co-stimulatory family members and which are differentially expressed in cancers including, lung cancer, ovarian cancer, and colon cancer, and diagnostic and therapeutic usages.


Popular terms: [SEARCH]



Follow us on Twitter
twitter icon@FreshPatents

###

This listing is a sample listing of patent applications related to Polypeptide for is only meant as a recent sample of applications filed, not a comprehensive history. There may be associated servicemarks and trademarks related to these patents. Please check with patent attorney if you need further assistance or plan to use for business purposes. This patent data is also published to the public by the USPTO and available for free on their website. Note that there may be alternative spellings for Polypeptide with additional patents listed. Browse our RSS directory or Search for other possible listings.
     SHARE
  
         


FreshNews promo



0.6066

3834

2 - 1 - 81