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Polynucleotide

Polynucleotide-related patent applications - as published by the U.S. Patent and Trademark Office (USPTO).


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Targeted sequence detection by nanopore sensing of synthetic probes
Two Pore Guys, Inc.
December 07, 2017 - N°20170349940

Disclosed herein are methods and compositions for detection of one or more specific sequences of polynucleotides in a solution using a nanopore. In some embodiments, methods and compositions for identifying a polynucleotide in a sample or for target sequence detection of a polynucleotide are disclosed herein.
Noninterfering multipurpose compositions for collecting, transporting and storing biological samples
Longhorn Vaccines And Diagnostics, Llc
December 07, 2017 - N°20170349936

The invention is directed to compositions and methods for collecting, transporting, and storing microorganisms obtained from samples of biological, clinical, forensic, and environmental origin. Compositions preserve the viability of the collected organisms and permit the long-term storage of samples. Compositions are compatible with subsequent manipulation of the sample, including propagation and culture of the collected microorganisms, or isolation, purification, detection, ...
Compositions and methods related to beta-glucosidase
Danisco Us Inc.
December 07, 2017 - N°20170349922

The present compositions and methods relate to a beta-glucosidase from glomerella graminicola, polynucleotides encoding the beta-glucosidase, and methods of making and/or use thereof. Formulations containing the beta-glucosidase may be suitable for use in hydrolyzing lignocellulosic biomass substrates.
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Protease variants and polynucleotides encoding same
Novozymes A/s
December 07, 2017 - N°20170349890

The present invention relates to protease variants and methods for obtaining protease variants. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.
Alpha-amylases and polynucleotides encoding same
Novozymes A/s
December 07, 2017 - N°20170349887

The present disclosure relates to isolated polypeptides having alpha-amylase activity, polynucleotides encoding the polypeptides, nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing the polypeptides, and method of using polypeptides, including in ethanol production processes.
Ligand binding molecules and uses thereof
Vegenics Pty Limited
December 07, 2017 - N°20170349886

The present invention is directed to polynucleotides that encode vegfr-3 ligand binding molecules and uses thereof to modulate angiogenesis and/or lymphangiogenesis. A glycosylation sequon of wildtype vegfr-3 has been modified to eliminate glycosylation in the encoded ligand binding molecules.
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Polynucleotide Patent Applications
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Isolated polynucleotides and polypeptides, and methods of using same for increasing plant yield and/or ...
Evogene Ltd.
December 07, 2017 - N°20170349635

Provided are isolated polypeptides which are at least 80% homologous to seq id nos: 182-184, 186-202, 204-216, 219-223, 225, 227-232, 235-236, 238, 240-260, 262-268, 270-275, 277-287, 289-297, 3651-3671, 3686, 3720-3721, 3724, 3727, 3735, 3754, 3774, 3795-4304, 4316, 4374, 4425, 4464, 4481-4813, 4824, 4833, 4843-4844, 4867-4869, 4888, 4890-4891, 5005-5050, 5053-5070, 5093, 5217, 5231, 5233, 5239, 5246, 5255, 5257-5296, 5412, 5415-5429, 5447-5456, 5465-5673, 5675-5686, 5688-5695, 5697-5698, 5700, 5702-5707, 5709-5715, 5717-5785, 5831, 5869, 5980, 6010-6043, 6045-6053, 6055-6093, 6132, 6383, 6405, 6493, 6523, 6533-6537, and 6563-6589, isolated polynucleotides encoding same, nucleic acid constructs comprising same, transgenic cells ...
In vivo production of proteins
Modernatx, Inc.
December 07, 2017 - N°20170348436

The invention relates to compositions and methods for the preparation, manufacture and therapeutic use of polynucleotides, primary transcripts and mmrna molecules.
Serum albumin-binding fibronectin type iii domains
Janssen Biotech, Inc.
December 07, 2017 - N°20170348397

Fibronectin type iii domains (fn3) that specifically bind to serum albumin, related polynucleotides capable of encoding serum albumin-specific fn3 domains, cells expressing the fn3 domains, as well as associated vectors, detectably labeled fn3 domains and fn3 domains fused to a heterologous moiety are useful in extending the half-life of molecules in diagnostic and therapeutic applications.
Polymer coatings
Illumina, Inc.
November 30, 2017 - N°20170342487

The present disclosure relates to polymer coatings covalently attached to the surface of a substrate and the preparation of the polymer coatings, such as poly(n-(5-azidoacetamidylpentyl)acrylamide-co-acrylamide) (pazam), in the formation and manipulation of substrates, such as molecular arrays and flow cells. The present disclosure also relates to methods of preparing a substrate surface by using beads coated with ...
Methods for sequencing a polynucleotide template
Illumina Cambridge Limited
November 30, 2017 - N°20170342482

The invention relates to methods for pairwise sequencing of a polynucleotide template which result in the sequential determination of nucleotide sequence in two distinct and separate regions of the polynucleotide template.
Polynucleotide amplification using crispr-cas systems
Illumina, Inc.
November 30, 2017 - N°20170342474

A method for amplifying a target nucleic acid including providing a system having a crrna or a derivative thereof, and a cas protein or a variant thereof. The crrna or the derivative thereof contains a target-specific nucleotide region substantially complementary to a region of the target nucleic acid, and contacting the target nucleic acid with the system to form a ...
Integration of a polynucleotide encoding a polypeptide that catalyzes pyruvate to acetolactate conversion
Butamax Advanced Biofuels Llc
November 30, 2017 - N°20170342445

The invention relates to recombinant host cells having at least one integrated polynucleotide encoding a polypeptide that catalyzes a step in a pyruvate-utilizing biosynthetic pathway, e. G., pyruvate to acetolactate conversion. The invention also relates to methods of increasing the biosynthetic production of isobutanol, 2,3-butanediol, 2-butanol or 2-butanone using such host cells.
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  • 877+ full patent PDF documents of Polynucleotide-related inventions.
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Chloroplast expressing colostrum or milk polypeptides
The Regents Of The University Of California
November 30, 2017 - N°20170342434

Provided are chloroplasts engineered to recombinantly express mammalian colostrum and milk polypeptides photosynthetic organisms containing such chloroplasts, and compositions comprising such organisms and methods for producing such organisms. In certain embodiments, provided is a chloroplast comprising one or more polynucleotides encoding one or more mammalian milk or colostrum polypeptides selected from osteopontin, lactadherin, cathelicidin-1, lysozyme, lactoperoxidase, lingual antimicrobial peptide (lap), ...
Expression of microbial proteins in plants for production of plants with improved properties
Monsanto Technology Llc
November 30, 2017 - N°20170342433

Recombinant constructs and methods useful for improvement of plants are provided. In particular, recombinant constructs comprising promoters functional in plant cells positioned for expression of polynucleotides encoding polypeptides from microbial sources are provided. The disclosed constructs and methods find use in production of transgenic plants to provide plants, particularly crop plants, having improved properties.
Methods and compositions for the introduction and regulated expression of genes in plants
Pioneer Hi-bred International, Inc.
November 30, 2017 - N°20170342431

Compositions and methods are provided for the introduction and the regulated expression of genes in plants. Compositions include promoter constructs that provide a level of activity useful for the regulated expression of site-specific recombinases, while avoiding premature excision. Further provided are isolated polynucleotides encoding novel babyboom polypeptides, expression cassettes, and plants comprising the same. Methods for the introduction of genes ...
Sequence variants
Sandoz Ag
November 30, 2017 - N°20170342422

Amino acid residue misincorporations are necessarily found in sequence variants at low concentrations in admixture with expressed polypeptides, resulting from one or more base mismatches within codons susceptible to amino acid residue misincorporation during transcription and/or translation. The invention provides a method of optimizing the coding sequences of a polynucleotide that encodes a polypeptide, wherein at least one codon ...
Partitioning and processing of analytes and other species
10x Genomics, Inc.
November 30, 2017 - N°20170342404

The present disclosure provides compositions, methods, systems, and devices for polynucleotide processing. Such polynucleotide processing may be useful for a variety of applications, including polynucleotide sequencing.
Protease variants and polynucleotides encoding same
Novozymes A/s
November 30, 2017 - N°20170342396

The present invention relates to protease variants and methods for obtaining protease variants. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.
Glucoamylase variants and polynucleotides encoding same
Novozymes A/s
November 30, 2017 - N°20170342393

The present invention relates to glucoamylase variants having improved thermostability. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.
A method for controlling glycosylation of recombinant glycoprotein
Lg Chem, Ltd.
November 30, 2017 - N°20170342392

The present invention relates to a method for controlling a glycosylation pattern of a recombinant glycoprotein, comprising culturing a cell comprising polynucleotide encoding a recombinant glycoprotein in a culture medium comprising insulin.
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