Images List Premium Download Classic

Polynucleotide

Polynucleotide-related patent applications - as published by the U.S. Patent and Trademark Office (USPTO).


loading
Microarray slides that enhance fluorescent signals via plasmonic interaction
Biochemistry
February 15, 2018 - N°20180045644

The invention describes generating and use of a multi-layer plasmonic slide, wherein the plasmonic slide comprises at least 6 layers of metallic nanoparticles that can enhance the detection of fluorescent signals and wherein the plasmonic slide can be printed as a microarray of any size. The microarray containing the plasmonic slide can further be printed with a protein, a glycan, or ...
Single nucleotide detection method
Medical Research Council
February 15, 2018 - N°20180044729

A method for determining the sequence of nucleotide bases in a polynucleotide analyte is provided. It is characterised by the steps of (1) generating a stream of single nucleotide bases from the analyte by pyrophosphorolysis; (2) producing captured molecules by reacting each single nucleotide base with a capture system labelled with detectable elements in an undetectable state; (3) releasing the detectable elements from ...
Single nucleotide detection method
Medical Research Council
February 15, 2018 - N°20180044728

A method for determining the sequence of nucleotide bases in a polynucleotide analyte is provided. It is characterised by the steps of (1) generating a stream of single nucleotide bases from the analyte by pyrophosphorolysis; (2) producing captured molecules by reacting each single nucleotide base with a capture system labelled with detectable elements in an undetectable state; (3) releasing the detectable elements from ...
Polynucleotide Patent Pack
Download 877+ patent application PDFs
Polynucleotide Patent Applications
Download 877+ Polynucleotide-related PDFs
For professional research & prior art discovery
inventor
  • 877+ full patent PDF documents of Polynucleotide-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
Nucleotide polymorphism detection method
Base4 Innovation Ltd
February 15, 2018 - N°20180044721

A method for characterising a dna analyte comprised of one or more polynucleotide types characteristic of a site of nucleotide polymorphism each of which includes a target region having the formula -x-y-z- wherein x and z are respectively first and second characteristic flanking oligonucleotide regions and y is one of the variants constituting the site is provided. The method is ...
Mate pair library construction
Bgi Shenzhen Co., Limited
February 15, 2018 - N°20180044668

The present invention provides a novel method for ligating an adapter to a target polynucleotide and methods of generating a library of mate-pair polynucleotide constructs that employ such a ligation method. Libraries and arrays comprising mate-pair polynucleotide constructs, and methods of sequencing libraries and arrays comprising mate-pair polynucleotide constructs, are also provided.
Cellobiohydrolase variants and polynucleotides encoding same
Novozymes A/s
February 15, 2018 - N°20180044652

The present invention relates to cellobiohydrolase variants. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.
Polynucleotide Patent Pack
Download 877+ patent application PDFs
Polynucleotide Patent Applications
Download 877+ Polynucleotide-related PDFs
For professional research & prior art discovery
inventor
  • 877+ full patent PDF documents of Polynucleotide-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
Modified immunocyte, method for producing modified immunocyte and utilization thereof
Riken
February 15, 2018 - N°20180044631

A modified immunocyte: (1) which expresses an exogenous unmodified t cell receptor α-chain and an exogenous t cell receptor β-chain on the cell surface thereof; or (2) which contains a polynucleotide encoding a t cell receptor α-chain and a polynucleotide encoding a t cell receptor β-chain. Thus, a new tool whereby immunity can be ...
Urlc10-derived peptide and vaccine containing same
Oncotherapy Science, Inc.
February 15, 2018 - N°20180042954

The present invention provides urlc10-derived epitope peptides having the ability to induce cytotoxic t cells. The present invention further provides polynucleotides encoding the peptides, antigen-presenting cells presenting the peptides, and cytotoxic t cells targeting the peptides, as well as methods of inducing the antigen-presenting cells or ctls. The present invention also provides compositions and pharmaceutical compositions containing them as ...
Cochleates and methods of using the same to enhance tissue penetration of pharmacologically active agent
Matinas Biopharma Nanotechnologies, Inc.
February 15, 2018 - N°20180042849

A cochleate composition is disclosed. Following oral administration of the cochleate composition, the pharmacologically active agent is found at higher concentrations in the tissue relative to plasma. Oral administration of these cochleate compositions also preferentially targets infected or inflamed tissue as compared to tissue in a healthy subject. The cochleate composition contains a size-regulating agent that reduces cochleate particle size, ...
Kits and methods for pathogen detection
University Of Miami
February 08, 2018 - N°20180037947

Kits and methods for detecting pathogens without the need for laboratory equipment are disclosed. The kits and methods described herein allow for near-room temperature amplification of pathogen polynucleotides in a biological sample in a one-compartment reaction vessel. The kits and methods may be used to detect any target nucleic acid, such as dna or rna from a bacterial, fungal, or ...
Treatment of nanog related diseases by inhibition of natural antisense transcript to nanog
Curna, Inc.
February 08, 2018 - N°20180037891

The present invention relates to antisense oligonucleotides that modulate the expression of and/or function of nanog, in particular, by targeting natural antisense polynucleotides of nanog. The invention also relates to the identification of these antisense oligonucleotides and their use in treating diseases and disorders associated with the expression of nanog.
Antisense polynucleotides to induce exon skipping and methods of treating dystrophies
The University Of Chicago
February 08, 2018 - N°20180037889

Antisense polynucleotides and their use in pharmaceutical compositions to induce exon skipping in targeted exons of the gamma sarcoglycan gene are provided, along with methods of preventing or treating dystrophic diseases such as limb-girdle muscular dystrophy.
Engineered phenylalanine ammonia lyase polypeptides
Codexis, Inc.
February 08, 2018 - N°20180037880

The present invention provides engineered phenylalanine ammonia-lyase (pal) polypeptides and compositions thereof, as well as polynucleotides encoding the engineered phenylalanine ammonia-lyase (pal) polypeptides.
Polynucleotide Patent Pack
Download 877+ patent application PDFs
Polynucleotide Patent Applications
Download 877+ Polynucleotide-related PDFs
For professional research & prior art discovery
inventor
  • 877+ full patent PDF documents of Polynucleotide-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
Anti- gprc5d antibodies, bispecific antigen binding molecules that bind gprc5d and cd3, and ...
Janssen Pharmaceutica Nv
February 08, 2018 - N°20180037651

Provided herein are antibodies that specifically bind to gprc5d. Also described are related polynucleotides capable of encoding the provided gprc5d-specific antibodies or antigen-binding fragments, cells expressing the provided antibodies or antigen-binding fragments, as well as associated vectors and detectably labeled antibodies or antigen-binding fragments. In addition, methods of using the provided antibodies are described. For example, the provided ...
Anti-infective binding proteins that bind aip2
Sorrento Therapeutics, Inc.
February 08, 2018 - N°20180037638

There is disclosed compositions and methods relating to or derived from anti-aip2 antibodies. More specifically, there is disclosed fully human antibodies that bind aip2, aip2-binding fragments and derivatives of such antibodies, and aip2-binding polypeptides comprising such fragments. Further still, there is disclosed nucleic acids encoding such antibodies, antibody fragments and derivatives and polypeptides, cells comprising such polynucleotides, methods ...
Bispecific egfr/igfir binding molecules
Bristol-myers Squibb Company
February 08, 2018 - N°20180037631

The present invention relates to bispecific molecules comprising an egfr binding domain and a distinct igfir binding domain for use in diagnostic, research and therapeutic applications. The invention further relates to cells comprising such proteins, polynucleotide encoding such proteins or fragments thereof, and vectors comprising the polynucleotides encoding the innovative proteins. Exemplary bispecific molecules include antibody-like protein dimers based on ...
Microorganism with enhanced l-lysine producibility and method for producing l-lysine using the same
Cj Cheiljedang Corporation
February 08, 2018 - N°20180037615

The present disclosure relates to a novel modified rna polymerase sigma factor a (siga) polypeptide; a polynucleotide encoding the same; a microorganism containing the polypeptide; and a method for producing l-lysine using the microorganism.
Delivery of polynucleotides using recombinant aav9
Nationwide Children's Hospital
February 08, 2018 - N°20180036431

The present invention relates to adeno-associated virus 9 methods and materials useful for systemically delivering polynucleotides across the blood brain barrier. Accordingly, the present invention also relates to methods and materials useful for systemically delivering polynucleotides to the central and peripheral nervous systems. The present invention also relates to adeno-associated virus type 9 methods and materials useful for intrathecal delivery of polynucleotides. ...
Single walled carbon nanotube polynucleotide complexes and methods related thereto
Ensysce Biosciences, Inc.
February 08, 2018 - N°20180036374

The present invention provides single-walled carbon nanotube formulations for the delivery of bioactive agents including large polynucleotides encoding therapeutic proteins into hard-to-transfect cells and methods of making such single-walled carbon nanotube formulations.
Compositions and methods of altering cholesterol levels
Moderna Tx, Inc.
February 08, 2018 - N°20180036369

The present invention relates to compositions, methods and kits using polynucleotides, primary transcripts and mmrna molecules.
Systems and methods for expression-based classification of thyroid tissue
Genomedx Biosciences, Inc.
February 01, 2018 - N°20180030540

A system for classifying thyroid nodule tissue as malignant or benign is provided that is based on the identification of sets of gene transcripts, which are characterized in that changes in expression of each gene transcript within a set of gene transcripts can be correlated to with either malignant or benign thyroid nodule disease. The thyroid classification system provides for ...
Loading