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Platelet patents

      

This page is updated frequently with new Platelet-related patent applications.




new patent Platelet-derived growth factor compositions and methods of use thereof
A method for promoting growth of bone, periodontium, ligament, or cartilage in a mammal by applying to the bone, periodontium, ligament, or cartilage a composition comprising platelet-derived growth factor at a concentration in the range of about 0.1 mg/ml to about 1.0 mg/ml in a pharmaceutically acceptable liquid carrier and a pharmaceutically-acceptable solid carrier.. .
Biomimetic Therapeutics, Llc


new patent Methods for treating wounds
Novel compositions for treating wounds and promoting the healing thereof are described, including composition containing novel combinations of a carrier and recombinant platelet derived growth factor having fewer isoforms and enhanced biostability. Methods of treating wounds with novel therapeutic composition using dosing procedures leading to effective results with a minimal number of treatment applications are also described..

new patent Platelet-derived growth factor compositions and methods of use thereof
A method for promoting growth of bone, periodontium, ligament, or cartilage in a mammal by applying to the bone, periodontium, ligament, or cartilage a composition comprising platelet-derived growth factor at a concentration in the range of about 0.1 mg/ml to about 1.0 mg/ml in a pharmaceutically acceptable liquid carrier and a pharmaceutically-acceptable solid carrier.. .
Biomimetic Therapeutics, Llc


new patent Platelet-derived growth factor compositions and methods of use thereof
A method for promoting growth of bone, periodontium, ligament, or cartilage in a mammal by applying to the bone, periodontium, ligament, or cartilage a composition comprising platelet-derived growth factor at a concentration in the range of about 0.1 mg/ml to about 1.0 mg/ml in a pharmaceutically acceptable liquid carrier and a pharmaceutically-acceptable solid carrier.. .
Biomimetic Therapeutics, Llc


Method and automated platelet identification within a whole blood sample from microscopy images
A method and apparatus for identifying platelets within a whole blood sample. The method includes the steps of: a) adding at least one colorant to the whole blood sample, which colorant is operable to tag platelets; b) disposing the blood sample into a chamber defined by at least one transparent panel; c) imaging at least a portion of the sample quiescently residing within the chamber to create one or more images; and d) identifying one or more platelets within the sample using an analyzer adapted to identify the platelets based on quantitatively determinable features within the image using a analyzer, which quantitatively determinable features include intensity differences..
Abbott Point Of Care, Inc.


Erythrocyte sedimentation inhibitor
The present invention addresses a problem in which, when examining blood properties in measurements of thrombus formation capacity and platelet function or the like, measurement data is changed as a result of sedimentation of blood in reservoirs during measurement. An erythrocyte membrane ion transport inhibitor, such as disodium 4,4′-dinitrostilbene-2,2′-disulfonate (dnds) or 4,4′-diisothiocyanatostilbene-2,2′-disulfonic acid (dids), is used to inhibit erythrocyte sedimentation, and accurate measurement data is obtained..
Fujimori Kogyo Co., Ltd.


Industrial lubricant including metal chalcogenide particles and phosphorus-based additive
An industrial lubricant composition including an oil base selected from the group consisting of vegetable oil, group i, group ii, group iii, group iv, group v and combinations thereof and a phosphorus-based non-chlorine additive. The industrial lubricant also includes at least one intercalation compound of a metal chalcogenide, a carbon containing compound and a boron containing compound, wherein the intercalation compound may have a geometry that is a platelet shaped geometry, a spherical shaped geometry, a multi-layered fullerene-like geometry, a tubular-like geometry or a combination thereof..
Nanotech Industrial Solutions, Inc.


Graphene reinforced polyethylene terephthalate
A composition and a method are provided for graphene reinforced polyethylene terephthalate (pet). Graphene nanoplatelets (gnps) comprising multi-layer graphene are used to reinforce pet, thereby improving the properties of pet for various new applications.
Niagara Bottling, Llc


Graphene reinforced polyethylene terephthalate
A composition and a method are provided for graphene reinforced polyethylene terephthalate (pet). Graphene nanoplatelets comprising a suitable initial surface area are added to a solvent for producing pet.
Niagara Bottling, Llc


Metal chelate compounds for binding to the platelet specific glycoprotein iib/iiia
The present invention is directed to compounds that bind to glycoprotein iib/iiia and can be used for diagnostic imaging, in particular magnetic resonance imaging of thrombi. The disclosed compounds enable the binding to glycoprotein iib/iiia receptor combined with an adequate imaging sensitivity..
Bayer Pharma Aktiengesellschaft


Method for controlling a blood component separation device including temporarily storing a component in a container

The object of the invention is to provide a blood separation device that can reduce the total time for drawing blood to obtain high-concentration platelet liquid, thereby reducing the binding time of the blood donor. The device includes a temporary storage bag (y2) (also serves as a buffy coat bag) which is a whole blood bag for storing whole blood drawn from a blood donor.
Terumo Kabushiki Kaisha

Film and coatings from nanoscale graphene platelets

A composite material includes a magnesium alloy and a layer consisting of nanoscale graphene platelets on at least a part of the surface of the magnesium alloy. A process for manufacturing such a composite material includes providing a magnesium alloy, providing nanoscale graphene platelets and applying the nanoscale graphene platelets to at least a part of the surface of the magnesium alloy..
Airbus Defence And Space Gmbh

Determination of platelet-mirnas in alzheimer's disease

The present invention relates to methods, kits and uses for determining platelet-mirnas in a from a platelet-comprising fraction derived from a whole blood sample from a subject affected or suspected to be affected by alzheimer's disease.. .
Hummingbird Diagnostics Gmbh

Colored platelets

A colored platelet including a substrate, an adhesion layer, a color pigment layer, and a secure layer and a method of producing the colored platelet are described. The disclosed colored platelet can provide a superior bright color effect in a coating composition.
Silberline Manufacturing Company, Inc.

4-((2-hydroxy-3-methoxybenzyl)amino)benzenesulfonamide derivatives as potent and selective inhibitors of 12-lipoxygenase

Human lipoxygenases (loxs) are a family of iron-containing enzymes involved in catalyzing the oxidation of polyunsaturated fatty acids to provide the corresponding bioactive hydroxyeicosatetraenoic acid (hete) metabolites. These eicosanoid signaling molecules are involved in a number of physiologic responses such as platelet aggregation, inflammation, and cell proliferation.
Thomas Jefferson University

Wound healing composition

The present invention relates to compositions for use in pharmaceutical, cosmetic and cosmeceutical applications, particularly wound healing, including the treatment of lesions and burns. In particular, the present invention relates to compositions comprising platelet enriched plasma (prp) and stem cell conditioned medium (sc cm) for use in pharmaceutical, cosmetic and cosmeceutical applications such as wound healing..

Methods and devices for preparation of enriched biological fluids

The present disclosure relates to methods and apparatus for producing platelet rich plasma, bone marrow mononuclear cells, stromal vascular fraction from adipose tissue, and other concentrated or enriched biological fluids.. .
Arthrex, Inc.

Use of blood flow parameters to monitor or control the dosing of anti-platelet agents

The invention comprises a method of using blood flow parameters to optimize the therapeutic efficacy of an antiplatelet agent in the treatment of a disease or disorder associated with abnormal hemodynamic thrombogenicity in a subject.. .
Rheovector, Llc

Platelet activation and growth factor release using electric pulses

Methods and systems for releasing growth factors are disclosed. In certain embodiments, a blood sample is exposed to a sequence of one or more electric pulses to trigger release of a growth factor in the sample.
General Electric Company

Platelet activation and growth factor release using electric pulses

Methods and systems for releasing growth factors are disclosed. In certain embodiments, a blood sample is exposed to a sequence of one or more electric pulses to trigger release of a growth factor in the sample.
General Electric Company

Use of platelet rich plasma composition in the treatment of cardiac conduction abnormalities

Methods and kits for treating a cardiac arrhythmia using a platelet rich plasma (prp) composition are provided. Any type of arrhythmia may be treated using the prp composition.

Modulation of the physical interaction between platelets and the cell surface effecting cell proliferation

The growth and/or proliferation of mammalian cells are modulated by modulating the physical interaction between platelets (thrombocytes) and the surface of the cells. Sulfated polysaccharides, preferably glycosaminoglycans, can be used as a medicament for the inhibition of the physical interaction between the cell surface and platelets in the treatment of a medical disorder associated with unwanted cell growth and/or proliferation.
Cell Receptor Gmbh

Fluidics devices for individualized coagulation measurements and associated systems and methods

The present technology relates generally to fluidics devices for measuring platelet coagulation and associated systems and methods. In some embodiments, a fluidics device includes an array of microstructures including pairs of generally rigid blocks and generally flexible posts.
University Of Washington

Method and kit for determining the probability that a patient will develop a severe case of dengue

A method for determining, in vitro, the probability of a patient developing severe dengue, based on a blood sample, in which: a) the quantity in the blood sample of at least one marker, which is platelet factor 4, is determined; b) the quantity of platelet factor 4 determined in step a) is compared with a reference quantity of the marker obtained from a group of individuals who have been diagnosed with non-severe dengue, wherein, if the quantity of platelet factor 4 determined in step a) is less than the reference quantity established in step b), it is determined that the patient will develop severe dengue.. .
Biomerieux

Activators of cxcr3 for the treatment of angiopathies of the eye

The present disclosure describes methods of treating angiogenic disorders of the eye, such as macular degeneration, restenosis following glaucoma treatment or diabetic retinopathy, by administering an activator of c-x-c chemokine receptor 3 (cxcr3). In some embodiments, the activator of cxcr3 is interferon-γ-inducible 10 kda protein (ip-10) or a fragment or variant thereof, such as a fragment comprising or consisting of the c-terminal α-helix of ip-10.
University Of Pittsburgh - Of The Commonwealth System Of Higher Education

Patterned nano graphene platelet-based conductive inks

A nano graphene platelet-based conductive ink comprising: (a) nano graphene platelets (preferably un-oxidized or pristine graphene), and (b) a liquid medium in which the nano graphene platelets are dispersed, wherein the nano graphene platelets occupy a proportion of at least 0.001% by volume based on the total ink volume and a process using the same. The ink can also contain a binder or matrix material and/or a surfactant.

Highly conductive graphitic films

A flexible graphene platelet-filled composite film comprising a carbon or graphitic matrix and 1% to 99% weight fraction of graphene platelets dispersed in the matrix, wherein the graphene platelets are aligned along planar directions of said film and are selected from pristine graphene, oxidized graphene, reduced graphene oxide, fluorinated graphene, hydrogenated graphene, doped graphene, chemically functionalized graphene, or a combination thereof, and wherein the carbon or graphitic matrix is obtained by carbonizing a carbon precursor polymer at a carbonization temperature of at least 300° c. Or by carbonizing and graphitizing the carbon precursor polymer at a final graphitization temperature higher than 1,500° c., and the graphitic matrix comprises graphene layers that are substantially oriented parallel to one another with an inclination angle between two graphene layers less than 5 degrees.

Persevere-ii: redefining the pediatric sepsis biomarker risk model with septic shock phenotype

The methods disclosed herein relate to an improved tool incorporating platelet count into a multi-biomarker based outcome risk stratification model for evaluating mortality risk in pediatric patients having sepsis. The methods described here are useful for treating sepsis, for point of care clinical decision support, for stratifying septic shock patients based on baseline mortality risk, and for clinical trial design, among other uses..
Children's Hospital Medical Center

Activation of (na++k+)-atpase inhibits platelet aggregation and prevents thrombosis

Methods of inhibiting platelet aggregation using antibodies having binding specificity for the α subunit of the (na++k+)-atpase are provided, along with methods for inhibiting or preventing or treating thrombosis in a subject using such antibodies.. .

Compounds and methods for delivery of prostacyclin analogs

This invention pertains generally to prostacyclin formulations and methods for their use in promoting vasodilation, inhibiting platelet aggregation and thrombus formation, stimulating thrombolysis, inhibiting cell proliferation (including vascular remodeling), providing cytoprotection, preventing atherogenesis and inducing angiogenesis.. .
United Therapeutics Corporation

Inhibition of platelet activation, aggregation and/or adhesion by hypothermia

A method for treating acute coronary syndromes (i.e., unstable angina or non-q-wave mi) or transient ischemic attacks in a human or animal patient by placing a heat exchange apparatus in the patient=s vasculature and using that heat exchange apparatus to cool the patient to a temperature (e.g. 30-36 degrees c.) at which platelet inhibition (i.e., inhibition of platelet activation and/or aggregation and/or adhesion) occurs.
Zoll Circulation Inc.

Electrode assembly for measurement of platelet function in whole blood

A platelet impedance measurement system including an electrode assembly allows for measurement of platelet function in blood. The assembly includes a substrate that acts as a substantially rigid base and includes an electrode.
Ca Casyso Ag

Synthetic platelets

Provided herein are various functionalized particles comprising a shell, dendritic linkers, and functional moieties. The dendrimer linkers allow very large numbers of functional moieties to be bound to the shell.
The Regents Of The University Of California

Two-dimensional materials and uses thereof

Various systems and methods relating to two-dimensional materials such as graphene. A membrane include a cross-linked graphene platelet polymer that includes a plurality of cross-linked graphene platelets.
Lockheed Martin Corporation

Hollow fiber membrane module for cleaning platelet suspension

A hollow fiber membrane module is capable of producing washed platelets having a low total protein amount and a high total platelet count from a platelet suspension. The hollow fiber membrane module for washing platelets by removal of impurities from a platelet suspension includes a housing having a platelet suspension inlet, washed platelet outlet, and filtrate outlet; and a hollow fiber membrane for filtering the platelet suspension, wherein pores through which the platelets do not pass, while the impurities pass, are formed, which hollow fiber membrane is arranged inside the housing; wherein the capacity of the inlet-side space which communicates with the platelet suspension inlet and stores the platelet suspension before being filtered through the hollow fiber membrane in the housing is 30 to 400 ml, and the module water permeability is 50 to 300 ml/pa/hr..
Toray Industries, Inc.

Quantum platelet converter

In one aspect a light emitting device includes a light emitting diode (led) chip, and an encapsulant covering the led chip. The encapsulant is embedded with a downconverter.
Seoul Semiconductor Co., Ltd.

Automated methods and systems for washing platelet concentrates

Automated systems and methods for providing platelet concentrates and synthetic storage media with reduced residual plasma volumes are disclosed. The disclosed systems and methods reduce the residual volume of plasma in platelet concentrate to obtain a platelet product having a volume of plasma that is approximately 5% or less of the total platelet product volume.
Fenwal, Inc.

Composite structure of graphene and carbon nanotube and manufacturing the same

The present invention discloses a composite structure of graphene and carbon nanotube and a method of manufacturing the same. The composite structure includes graphene platelets and carbon nanotubes, each carbon nanotube growing perpendicular to the planar surface of the graphene platelet.
Enerage Inc.

Processes for producing effects layers

The invention relates to the field of the protection of security documents such as for example banknotes and identity documents against counterfeit and illegal reproduction. In particular, the present invention provides processes for producing optical effect layers (oels) on a substrate and oels obtained thereof, said process comprising two magnetic orientation steps: a step of exposing a coating composition comprising platelet-shaped magnetic or magnetisable pigment particles to a dynamic magnetic field of a first magnetic-field-generating device so as to bi-axially orient at least a part of the platelet-shaped magnetic or magnetisable pigment particles and a step of exposing the coating composition to a static magnetic field of a second magnetic-field-generating device, thereby mono-axially reorienting at least a part of the platelet-shaped magnetic or magnetisable pigment particles..
Sicpa Holding Sa

Centrifuge separating blood components

A centrifuge apparatus for separating blood components includes a centrifuge tube and a flow dividing mechanism, and the flow dividing mechanism is fixed at the bottom of the centrifuge tube. Moreover, the bottom of the centrifuge tube is further provided with a discharge hole.
Shanghai Jiao Tong University Affiliated Sixth People's Hospital

Platelet decoys and use thereof

The invention provides platelet decoys and mimics that can bind to platelet receptor substrate but do not undergo platelet activation. The invention also provides methods of using the platelet decoys for treating, preventing or inhibiting a disease or disorder in subject when platelet activation, aggregation and/or adhesion contributes to the pathology or symptomology of the disease..
President And Fellows Of Harvard College

Use of atractylenolide compound or its derivatives and a medicament for inhibiting platelet aggregation

A medicament for inhibiting platelet aggregation, comprising atractylenolide compound or its derivatives, wherein the said atractylenolide compound has the following structural formula shown in formula (i), wherein r1 represents h or c1-c10 linear or branched alkyl, r2 represents h or c1-c10 linear or branched alkyl, and r3 represents h or hydroxyl. Use of atractylenolide compound shown in formula (i) or its derivatives in the manufacture of a medicament for inhibiting platelet aggregation.
No.3 People Hospital Affiliated To Shanghai Jiaotog University School Of Medicine



Platelet topics:
  • Growth Factor
  • Fibroblast
  • Nanoparticle
  • Autologous
  • Leukocytes
  • Circulation
  • Transforming Growth Factor
  • Therapeutical
  • Platelet Derived Growth Factor
  • Bone Morphogenetic Protein
  • Endothelial
  • Recombinant
  • Stem Cells
  • Respiratory System
  • Dispensing System


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    This listing is a sample listing of patent applications related to Platelet for is only meant as a recent sample of applications filed, not a comprehensive history. There may be associated servicemarks and trademarks related to these patents. Please check with patent attorney if you need further assistance or plan to use for business purposes. This patent data is also published to the public by the USPTO and available for free on their website. Note that there may be alternative spellings for Platelet with additional patents listed. Browse our RSS directory or Search for other possible listings.


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