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This page is updated frequently with new Platelet-related patent applications. Subscribe to the Platelet RSS feed to automatically get the update: related Platelet RSS feeds. RSS updates for this page: Platelet RSS RSS


Tube to produce platelet rich fibrin

Date/App# patent app List of recent Platelet-related patents
08/28/14
20140243502
 Anticoagulation agent and uses thereof patent thumbnailnew patent Anticoagulation agent and uses thereof
The present invention provides an anticoagulant agent including a first element capable of inhibiting coagulation and a second element capable of targeting an activated platelet wherein upon administration of the agent to a subject the second element directs the first element to the activated platelet. Also provided is a probe for detecting a blood vessel abnormality including (a) a binding element capable of targeting an activated platelet and (b) a label.
08/28/14
20140242262
 Carbon-based electrodes with graphene modification patent thumbnailnew patent Carbon-based electrodes with graphene modification
Certain embodiments of the present application describe a carbon-based electrode with graphene platelets. The addition of graphene platelets is intended to improve properties of the electrode.
08/28/14
20140242054
 Methods and compositions for treating respiratory conditions using platelet enriched plasma patent thumbnailnew patent Methods and compositions for treating respiratory conditions using platelet enriched plasma
Described herein are methods and compositions for the treatment of respiratory diseases such as, for example, exercise induced pulmonary hemorrhage. The methods include the use of compositions comprising platelet enriched plasma, for example, platelet rich plasma and/or platelet poor plasma, for treatment of respiratory diseases in humans and animals, in particular, equines, by administration to the respiratory system..
08/28/14
20140241957
 Tube to produce platelet rich fibrin patent thumbnailnew patent Tube to produce platelet rich fibrin
Invention; it is about the tubes used to obtain blood products through centrifuge order to cure open and closed injuries, to heal hard and soft tissues and to diagnose in all fields of medicine and dentistry. Platelet rich fibrin (prf) obtained in the tubes the surface of which contacts blood and made from pure titanium or titanium alloys has a better structure of fibrin than that is obtained through classical methods.
08/21/14
20140235868
 Novel antithrombotic and antiatherosclerotic agent and method for producing same (variants) patent thumbnailNovel antithrombotic and antiatherosclerotic agent and method for producing same (variants)
The use of 2-[2-cyano-2-[5-(hydroxymethyl)-3-methyl-1,3-oxazolidin-2-ylidene]ethylidene]indolin-3-one of formula i is proposed as a biologically active compound exhibiting the properties of exogenous nitric oxide donor, a platelet aggregation inhibitor, also exhibiting antihypertensive activity and activating activity towards the soluble guanylate cyclase enzyme. Variants of methods for synthesizing the above compound are also proposed..
08/21/14
20140235827
 Mouse anti-aggrus monoclonal antibodies patent thumbnailMouse anti-aggrus monoclonal antibodies
The present invention provides a monoclonal antibody or a functional fragment thereof, capable of recognizing aggrus epitope comprising an amino-acid sequence represented by a sequence id 1, 3, or 4, and the monoclonal antibody or the functional fragment thereof produced from a hybridoma with deposit id of ferm bp-11446, ferm bp-11447, ferm bp-11448 or ferm bp-11449. The present invention provides the hybridoma, and further an aggrus-clec-2 binding inhibitor and a pharmaceutical composition for inhibition of platelet aggregation, prevention of cancer metastasis, or treatment of tumor or cancer, comprising the monoclonal antibody or the functional fragment thereof..
08/21/14
20140234859
 Controlled platelet activation to monitor therapy of adp antagonists patent thumbnailControlled platelet activation to monitor therapy of adp antagonists
A method is provided of determining whether an individual has reduced ability to form platelet thrombi due to inhibition of platelet activation initiation, signal transduction and/or gpiib/iiia blockade. A blood sample is obtained from the individual being assessed.
08/21/14
20140234322
 Thrombopoietin mimetics for the treatment of radiation or chemical induced bone marrow injury patent thumbnailThrombopoietin mimetics for the treatment of radiation or chemical induced bone marrow injury
Disclosed are transgenic non-human mammals, which useful for the screening of thrombopoietin mimetics, thrombopoietin receptor agonists, or thrombopoietin receptor antagonists active on the human thrombopoietin receptor. The transgenic non-human mammal has a genome that comprises a stably integrated transgene construct comprising a polynucleotide sequence encoding a humanized thrombopoietin receptor wherein said transgenic non-human mammal has a baseline blood platelet count corresponding to a physiological blood platelet count of a matched non-transgenic non-human mammal.
08/14/14
20140228365
 Thiazole derivatives and use thereof patent thumbnailThiazole derivatives and use thereof
The present invention is related to thiazole derivatives of formula (i) in particular for the treatment and/or prophylaxis of autoimmune disorders and/or inflammatory diseases, cardiovascular diseases, neturodegenerative diseases, bacterial or viral infections, kidney diseases, platelet aggregation, cancer, transplantation, graft rejection or lung injuries.. .
08/14/14
20140227780
 Method for producing megakaryocytes and/or platelets from pluripotent stem cells patent thumbnailMethod for producing megakaryocytes and/or platelets from pluripotent stem cells
Where r1 to r7, w, x, y, z, ar1 and n are as defined in the description to differentiate them into megakaryocytes and/or platelets.. .
08/14/14
20140227678
Method for living tissue preservation
A method for platelet preservation comprising placing a composition comprising platelets in a gas mixture comprising xenon and oxygen under pressure of about 0-10 bars at a first temperature of about 18° c.-37° c. For a first period of time, and then subsequently cooling the composition to a second temperature of about 0,1° c.-6° c., and holding the composition under the pressure and in the second temperature for a second period of time..
08/14/14
20140227360
Stable pharmaceutical composition of clopidogrel free base for oral and parenteral delivery
The present disclosure provides ready-to-use, oil/water emulsion compositions with mean droplet size (intensity-average, m) of 100-500 nm, wherein the oil phase comprises clopidogrel free base dispersed in pharmaceutical acceptable oil(s). The emulsion uses clopidogrel free base or premix of clopidogrel free base in oil(s) as the starting materials and may also contain one or more excipients such as surfactant and or co-surfactant, osmotic agent, ph adjustment agent, antioxidant, preservative, sweetener, and/or suspending agent, etc.
08/14/14
20140227241
Serum fraction of platelet-rich fibrin
And further provides for the isolated serum fraction obtained by such method, and its medical use.. .
08/14/14
20140227240
Regeneration of spinal discs
Compositions and processes for the effective and efficient regeneration of spinal discs are provided. These compositions contain stem cells, donor cells, and platelet plasma compositions.
08/14/14
20140224466
Nano graphene platelet-reinforced composite heat sinks and process for producing same
An integrated heat sink article composed of a heat collection member and at least one heat dissipation member integral to the heat collection member, wherein the heat collection member is configured to be in thermal contact with a heat source, collects heat from the heat source, and dissipates heat through the at least one heat dissipation member, and further wherein the heat sink is formed of a nano graphene platelet-reinforced composite having nano graphene platelets or sheets (ngps) as a first reinforcement phase dispersed in a matrix material and the first reinforcement phase occupies a weight fraction of 1-90% based on the total composite weight. Preferably, these ngps, alone or in combination with a second reinforcement phase, are bonded by an adhesive and constitute a continuous 3-d network of electron- and phonon-conducting paths..
08/07/14
20140221405
Platelet adp receptor inhibitors
Novel compounds of formulae (i) to (vii), which more particularly include sulfonylurea derivatives, sulfonylthiourea derivatives, sulfonylguanidine derivatives, sulfonylcyanoguanidine derivatives, thioacylsulfonamide derivatives, and acylfulfonamide derivatives which are effective platelet adf receptor inhibitors. These derivatives may be used in various pharmaceutical compositions, and are particularly effective for the prevention and/or treatment of cardiovascular diseases, particularly those diseases related to thrombosis.
08/07/14
20140220694
Methods and compositions relating to platelet sensitivity
The invention identifies and describes proteins that are differentially expressed in platelets resistant to anti-platelet agents such as aspirin (acetylsalicyclic acid) compared to those platelets that are sensitive to such agents. Methods for determining further such differentially expressed proteins and methods for determining an individual's sensitivity to anti-platelet agents, such as aspirin, prior to administration..
07/31/14
20140213481
Method for the simultaneous determination of blood group and platelet antigen genotypes
Rbc and platelet (plt) alloimmunization requires antigen-matched blood to avoid adverse transfusion reactions. Some blood collection facilities use unregulated abs to reduce the cost of mass screening, and later confirm the phenotype with government approved reagents.
07/31/14
20140213480
Method for the simultaneous determination of blood group and platelet antigen genotypes
Rbc and platelet (plt) alloimmunization requires antigen-matched blood to avoid adverse transfusion reactions. Some blood collection facilities use unregulated abs to reduce the cost of mass screening, and later confirm the phenotype with government approved reagents.
07/31/14
20140212914
Method for purifying certain cell populations in blood or bone marrow by depleting others
A method for purifying and harvesting certain cell populations in blood or bone marrow by depleting at least one of red blood cells, granulocytes, or platelets from a sample comprising blood, bone marrow, or stromal vascular fraction cells separated from adipose tissue is disclosed. The apparatus comprises a sterile, single use rigid, self-supporting cartridge within which the automated depletion, purification and harvesting of target cell populations occurs and all components may be distributed..
07/31/14
20140212912
Purified cell population isolated from whole blood
A purified solution of human plasma, mncs and platelets isolated from whole blood, bone marrow, or stromal vascular fraction cells separated from adipose tissue wherein said purified solution comprises at least 90% by number of the mncs in said whole blood, bone marrow, or stromal vascular fraction cells separated from adipose tissue, said purified solution comprises at most 10% by number of the red blood cells and granulocytes in said whole blood, bone marrow, or stromal vascular fraction cells separated from adipose tissue, and said purified solution is isolated and separated from said whole blood, bone marrow, or stromal vascular fraction cells separated from adipose tissue during a single centrifugation run.. .
07/31/14
20140212656
Dispersion comprising carbon nanotubes and graphene platelets
A preferably aqueous dispersion comprises carbon nanotubes and graphene platelets, with the ratio by mass of carbon nanotubes to graphene platelets being situated within a range from ≧5:95 to ≦75:25. In a process for preparing a dispersion of this kind, carbon nanotubes and graphene platelets are combined so that the ratio by mass of carbon nanotubes to graphene platelets in the dispersion is in a range from ≧5:95 to ≦75:25.
07/31/14
20140212399
Hair growth agent having a platelet dry powder
A hair growth agent having an effective dose of a platelet dry powder and a pharmaceutically acceptable solvent and/or excipient, wherein the effective dose refers to the presence of at least 1,000 platelets in every milliliter of the hair growth agent.. .
07/31/14
20140212358
Nanoparticles for the treatment of radiation skin injury
The present invention is associated with a method of evaluating platelet function in vivo using skin-irradiation and nanoparticle radiation treatment. The present invention in the recovery of radiation skin injury suggests that radiation skin injury can be used as a substitute model to evaluate platelet substitute products instead of measuring bleeding times.
07/31/14
20140209393
Precipitated particles and wellbore fluids and methods relating thereto
Precipitated mineral particles may provide for wellbore fluids with tailorable properties and capabilities. Such wellbore fluids may be included as a portion of a wellbore drilling assembly that includes a pump in fluid communication with a wellbore via a feed pipe; and a wellbore fluid disposed in at least one selected from the group consisting of the pump, the feed pipe, the wellbore, and any combination thereof, wherein the wellbore fluid has a density of about 7 ppg to about 50 ppg and comprises a base fluid and a plurality of precipitated particles having a shape selected from the group consisting of ovular, substantially ovular, discus, platelet, flake, toroidal, dendritic, acicular, spiked with a substantially spherical or ovular shape, spiked with a discus or platelet shape, rod-like, fibrous, polygonal, faceted, star-shaped, and any hybrid thereof..
07/31/14
20140209386
Precipitated particles and wellbore fluids and methods relating thereto
A method of using precipitated particles in a wellbore may comprise circulating a wellbore fluid in a wellbore penetrating a subterranean formation, the wellbore fluid having a density of about 7 ppg to about 50 ppg and comprising a base fluid and a plurality of precipitated particles having a shape selected from the group consisting of ovular, substantially ovular, discus, platelet, flake, toroidal, dendritic, acicular, spiked with a substantially spherical or ovular shape, spiked with a discus or platelet shape, rod-like, fibrous, polygonal, faceted, star shaped, and any hybrid thereof.. .
07/24/14
20140206716
Methods and compositions for the assessment of drug response
The present invention provides methods for predicting or determining a subject's response to an antiplatelet agent, and methods for determining a subject's suitability to a treatment regime or intervention for a disease associated with platelet aggregation, using analysis of genetic polymorphisms. The present invention also relates to the use of genetic polymorphisms in assessing a subject's response to an antiplatelet agent.
07/24/14
20140206644
Methods and compositions for inhibiting cellular proliferation and surgical adhesion
The present invention provides compositions and methods to inhibit fibrosis and scarring associated with surgery. The present invention relates to the discovery that a synthetic anionic polymer consisting of dextran-sulfate (anionic carbohydrate) conjugated to tirofiban (an anti-platelet agent which prevents platelet activation and aggregation) can effectively inhibit adhesions that form during surgery.
07/24/14
20140205582
Megakaryocyte progenitor cells for production of platelets
Provided herein are methods of generating megakaryocyte lineage cells from hematopoietic stem cells in the absence of feeder cells and serum. The megakaryocyte progenitor cells (mkps) generated as described result in rapid production of significant numbers of platelets when administered in vivo..
07/24/14
20140205514
Blood separating vessel for extracting autologous platelets, and apparatus for extracting autologous platelets
Provided is a blood separating vessel for extracting autologous platelets, and an apparatus for extracting autologous platelets. The blood separating vessel for extracting autologous platelets comprises: a main body defining an internal space divided into an upper fluid chamber and a lower fluid chamber; an upper cover disposed to seal an upper portion of the upper fluid chamber; a lower cover disposed to seal a lower portion of the lower fluid chamber, the lower cover being coupled such that an outer peripheral surface of the lower cover is elevatable in a state of being in close contact along an inner peripheral surface of the lower fluid chamber by an external force applied upward; and a fluid collection part dividing the internal space into the upper fluid chamber and the lower fluid chamber and including a fluid passage protruding upward to communicate the upper fluid chamber with the lower fluid chamber..
07/24/14
20140205176
Optical platelet counter method
Platelets or blood cells are detected in a fluid sample by adjusting a focal depth of a microscope through a range of values, the microscope having a mounted sample and an objective lens adapted with one or both of (a) a spherical aberration correction unmatched to a utilized cover plate for the sample, or (2) a numerical aperture unmatched to a utilized illumination source for the sample. Images are recorded at different specific focal depths and in multiple z planes of a fluid bearing the platelets, where the position of platelets may overlap on different of the multiple z planes that are recorded, the images recorded through the cover plate, thus causing the generation of a specific light-dark pattern indicative of platelets at particular positions and at multiple depths in the fluid media.
07/17/14
20140200256
Acetylated amino acids as anti-platelet agents, nutritional and vitamin supplements
This invention relates to pharmaceutical compounds and nutritional supplements that are acetylated derivatives of naturally occurring amino acids and acetylated derivatives of peptides derived from naturally occurring amino acids containing hydroxyl groups. They are as useful as anti-platelet drugs, and as nutritional supplements..
07/17/14
20140200240
Methods for determining patient response to anti-platelet aggregation therapy
Diagnostic methods for determining whether an individual will benefit from a particular anti-thrombotic therapeutic agent are disclosed. The methods involve obtaining a biological sample that comprises platelets, from a patient who has been pre-administered a particular therapeutic agent, which is an antagonist of a receptor associated with the biochemical pathways involved in platelet aggregation, and exposing the platelets to an agonist of the receptor.
07/17/14
20140196684
Spark plug for an internal combustion engine
The invention relates to a spark plug for an internal combustion engine, in particular a gas engine. The spark plug includes a middle electrode and at least one earth electrode group, each comprising one or more earth electrode platelets.
07/10/14
20140194407
Novel antiplatelet agent
R3 is an optionally substituted aryl or an optionally substituted heteroaryl, or pharmaceutically acceptable salt thereof as an active ingredient.. .
07/10/14
20140193590
Surface-modified, exfoliated nanoplatelets as mesomorphic structures in solutions and polymeric matrices
A method of manufacturing a nanocomposite having a continuous organic phase and oligomer-modified nanoplatelet mesomorphic structures, wherein the oligomer has a molecular weight of at least 100 g/mol.. .
07/10/14
20140193485
Orally administrable liposomally encapsulated reduced glutathione, with ace inhibitors for reversal and prevention of oxidation of cholesterol and of low density lipoprotein
The invention proposes the combination of reduced glutathione in a liposome (liposomal reduced glutathione) with a specified concentration of reduced glutathione within the liposome for the oral administration of a therapeutically effective amount to ameliorate the progression of vascular disease, including atherosclerosis, diabetes, hypertension, narrowing of arteries leading to decreased blood flow, ischemic events, and the formation of blood clots, abnormal platelet aggregation, and thrombotic events, by reducing the amount and effect of oxidized cholesterol, oxidized hdl and oxidized ldl. The invention also proposes combining liposomal encapsulated glutathione with ace inhibitors in order to improve the effect of lowering not only cholesterol but also the oxidized cholesterol as well as oxidized hdl and oxidized ldl.
07/10/14
20140193402
Anti-pdgfr-beta antibodies and uses thereof
The present invention provides antibodies that bind to platelet derived growth factor receptor beta (pdgfr-beta) and methods of using the same. According to certain embodiments of the invention, the antibodies are fully human antibodies that bind to human pdgfr-beta with high affinity.
07/03/14
20140187643
Method of treatment with anti-inflammatory and analgesic compounds which are gi-, renal-, and platelet-sparing
Disclosed herein are compounds, pharmaceutical compositions, and methods for the treatment of diseases such as inflammation and/or pain, comprising the administration of a therapeutically effective amount of a non-steroidal, non-opioid compound having gi-/renal-/platelet-sparing activities, and wide safety margins with no appreciable inhibition of either form of cyclooxygenase.. .
07/03/14
20140186874
Immature platelet enumeration systems and methods
Embodiments of the present invention encompass automated systems and methods for analyzing immature platelet parameters in an individual based on a biological sample obtained from blood of the individual. Exemplary techniques involve correlating aspects of direct current (dc) impedance, radiofrequency (rf) conductivity, and/or light measurement data obtained from the biological sample with an evaluation of immature platelet conditions in the individual..
07/03/14
20140186455
Tissue repair system
An implant for promoting accelerated wound healing. The implant comprises a non-flocculating fiber material, admixed with a settable fluid.
07/03/14
20140186349
Human cdr-grafted antibody and antibody fragment thereof
A human cdr-grafted antibody or the antibody fragment thereof which specifically reacts with the extracellular region of human cc chemokine receptor 4 (ccr4) but does not react with a human blood platelet; a human cdr-grafted antibody or the antibody fragment thereof which specifically reacts with the extracellular region of ccr4 and has a cytotoxic activity against a ccr4-expressing cell; and a medicament, a therapeutic agent or a diagnostic agent comprising at least one of the antibodies and the antibody fragments thereof as an active ingredient.. .
07/03/14
20140186320
Methods and compositions for the treatment, prevention, and alleviation of bone and cartilage diseases or injuries and hair loss
The present invention provides pharmaceutical compositions, and methods of preparation and use for the treatment, prevention or alleviation of bone and cartilage diseases or injuries and hair loss. The present invention discloses a method and a pharmaceutical composition comprising mesenchymal stem cells, platelets, activating factors and scaffolding materials for the treatment, prevention, or alleviation of bone diseases, bone injuries or hair loss, and a method and a pharmaceutical composition further comprising dexamethasone for the treatment, prevention, or alleviation of cartilage diseases or injuries..
07/03/14
20140186217
Blood coagulation system analyzing method and blood coagulation system analyzing device
A blood coagulation analysis device and method in which information relating to the coagulability of blood is evaluated based on a change generated in a permittivity measured in a coagulation process of the blood due to addition of a substance that activates or inactivates platelets to the blood.. .
07/03/14
20140185031
Systems and methods for platelet count with clump adjustment
Embodiments of the present invention encompass automated systems and methods for analyzing platelet parameters in an individual based on a biological sample obtained from blood of the individual. Exemplary techniques involve correlating aspects of direct current (dc) impedance and/or light measurement data obtained from the biological sample with an evaluation of platelet conditions in the individual..
06/26/14
20140179766
Identification of thrombosis or bleeding risk in an individual with and without anti-platelet therapy
The invention relates to a method for identification of an individual at increased risk of thrombosis or an atherothrombotic event, or a major bleeding event, comprising a step of assaying a biological sample from the individual for the presence of a snp in the ppargc1β, cntn4, lzts1 and kcne4 genes, wherein the presence of a snp in the ppargc1β, cntn4, lzts1 and kcne4 genes correlates with the individual being at increased risk of thrombosis or an atherothrombotic event, or a major bleeding event. Typically, the snp is selected from the snps provided in tables 1 and 2.
06/26/14
20140179602
Viral inactivated biological mixture
The invention relates to a viral inactivated biological liquid or dry mixture and to its preparation. Principally, the invention relates, but is not limited, to a mixture derived from a platelet source..
06/19/14
20140171469
Pyrazolyl substituted carbonic acid derivatives as modulators of the prostacyclin (pgi2) receptor useful for the treatment of disorders related thereto
Pyrazole derivatives of formula ia and pharmaceutical compositions thereof that modulate the activity of the pgi2 receptor. Compounds of the present invention and pharmaceutical compositions thereof are directed to methods useful in the treatment of: pulmonary arterial hypertension (pah) and related disorders; platelet aggregation; coronary artery disease; myocardial infarction; transient ischemic attack; angina; stroke; ischemia-reperfusion injury; restenosis; atrial fibrillation; blood clot formation in an angioplasty or coronary bypass surgery individual or in an individual suffering from atrial fibrillation; atherosclerosis; atherothrombosis; asthma or a symptom thereof; a diabetic-related disorder such as diabetic peripheral neuropathy, diabetic nephropathy or diabetic retinopathy; glaucoma or other disease of the eye with abnormal intraocular pressure; hypertension; inflammation; psoriasis; psoriatic arthritis; rheumatoid arthritis; crohn's disease; transplant rejection; multiple sclerosis; systemic lupus erythematosus (sle); ulcerative colitis; ischemia-reperfusion injury; restenosis; atherosclerosis; acne; type 1 diabetes; type 2 diabetes; sepsis; and chronic obstructive pulmonary disorder (copd)..
06/19/14
20140170741
Hepatic fibrosis detection apparatus and system
A hepatic fibrosis detection apparatus and system include an input device, for receiving age and serum biochemical variables, the serum biochemical variables at least including blood platelet, hyaluronic acid, serum direct bilirubin, pro-thrombin time, serum glutamic pyruvic transaminase and serum glutamic oxaloacetic transaminase; a classifier, for performing hepatic fibrosis staging according to the age and serum biochemical variables received by the input device and transient elastography imaging data; and an output device, for outputting a result of the hepatic fibrosis staging of the classifier. The system provides various benefits such as non-invasiveness, high practicability, simple method, low cost and high safety..
06/19/14
20140170410
Method for applying a coating to a substrate, coating, and use of particles
The present invention relates to a method for applying a coating to a substrate using cold plasma, wherein particles provided with a polymer coating are fed into a cold plasma at less than 3,000 k and the particles activated by this are deposited on a substrate. The present invention furthermore relates to a substrate coating which can be obtained by the methods according to the invention.
06/19/14
20140166500
Method for producing thin graphene nanoplatelets and precusor thereof
Disclosed is a method of producing thin graphene nanoplatelets, and the method includes the steps of providing a carbon precursor and a filling material, using the carbon precursor as a binding agent to mix with the filling material thoroughly, producing a composite material through a forming process, performing a heat treatment of the composite material under an atmosphere and at different temperatures to improve the electrical conductivity and adjust to an appropriate binding strength, perform a carbon conversion of the composite material with a good graphite cyrstallinity to produce a layered graphite structure of a thin graphene nanoplatelet precursor, while obtaining high quality graphene by performing an electrochemical process of the thin graphene nanoplatelet precursor, so as to achieve the mass production of the high quality thin graphene nanoplateletes with a low cost.. .
06/19/14
20140165878
Interference pigment with high color intensity and method of manufacturing the same
The interference pigment with high color intensity includes: a platelet-shaped substrate including at least one of natural mica, synthetic mica, alumina flakes, glass flakes, and iron oxide flakes; a lower first metal oxide layer formed of fe2o3 on the platelet-shaped substrate; a second metal oxide layer formed of mgo.sio2 on the lower first metal oxide layer; and an upper first metal oxide layer formed of fe2o3 on the second metal oxide layer.. .
06/12/14
20140163090
Use of telomerase inhibitors for the treatment of myeloproliferative disorders and myeloproliferative neoplasms
Provided herein are methods for reducing neoplastic progenitor cell proliferation and alleviating symptoms associated in individuals diagnosed with or thought to have essential thrombocythemia (et). Also provided herein are methods for using telomerase inhibitors for maintaining blood platelet counts at relatively normal ranges in the blood of individuals diagnosed with or suspected of having et..
06/12/14
20140162364
Method for producing a porous calcium polyphosphate structure
A method for producing a porous calcium polyphosphate structure, which comprises the steps of mixing monocalcium phosphate (mcp) with silicic acid, and sintering the mixture at a predefined temperature or temperatures for a predefined time, after which the porous calcium polyphosphate is obtained. The method allows a porous biomaterial with a controllable porosity to be obtained, and which also has the ability to activate the platelets in a plasma rich in platelets and cause the release of growth factors from the platelets..
06/12/14
20140161811
Platelet derived growth factor receptor supports cytomegalovirus infectivity
The disclosure relates generally to compositions and methods useful for inhibiting the infection and propagation of viral particles, particularly members of the herpesviridae family, and more particularly to cytomegalovirus (cmv).. .
06/12/14
20140158604
Platelet storage container
Compositions, methods, devices and media are provided for platelet storage container that prevents bacterial growth in the stored platelets. The invention relates to blood bank needs in safely storing platelets collected from donors for more than 5 days at room temperature.
06/12/14
20140158556
Platelets storage container
A storage container for pathogen reduction and maintaining ph levels for preserved platelets concentrates and other blood products.. .


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Platelet topics: Growth Factor, Fibroblast, Nanoparticle, Autologous, Leukocytes, Circulation, Transforming Growth Factor, Therapeutical, Platelet Derived Growth Factor, Bone Morphogenetic Protein, Endothelial, Recombinant, Stem Cells, Respiratory System, Dispensing System

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