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Platelet patents



      
           
This page is updated frequently with new Platelet-related patent applications. Subscribe to the Platelet RSS feed to automatically get the update: related Platelet RSS feeds. RSS updates for this page: Platelet RSS RSS


Centrifuge

Centrifuge

Date/App# patent app List of recent Platelet-related patents
10/09/14
20140303084
 Pro-coagulant compounds and methods of use thereof patent thumbnailPro-coagulant compounds and methods of use thereof
Provided are pro-coagulant compounds (e.g., pro-coagulant peptides or peptide derivatives) and methods of using and making those compounds. Further provided are conjugates between a pro-coagulant compound of the present disclosure (e.g., pro-coagulant peptide or peptide derivative) and a polypeptide selected from fix, fviia, fviii, and platelet targeting moieties (e.g., pdg-13), wherein the compound is linked to the polypeptide optionally via a linker.
10/09/14
20140302976
 Centrifuge patent thumbnailCentrifuge
Centrifuges are useful to, among other things, remove red blood cells from whole blood and retain platelets and other factors in a reduced volume of plasma. Platelet rich plasma (prp) and or platelet poor plasma (ppp) can be obtained rapidly and is ready for immediate injection into the host.
10/09/14
20140302159
 Cosmetic composition comprising a superabsorbent polymer and a lamellar or platelet-shaped matting mineral filler patent thumbnailCosmetic composition comprising a superabsorbent polymer and a lamellar or platelet-shaped matting mineral filler
The present invention relates to a composition for topical application, comprising at least one aqueous phase, at least one superabsorbent polymer and at least one lamellar or platelet-shaped matting mineral filler. A subject of the invention is also a cosmetic treatment process for keratin materials, which consists in applying to the keratin materials a composition as defined above, and also the use of this composition in the cosmetic or dermatological field, and in particular for caring for, protecting and/or making up bodily or facial skin, or for haircare.
10/09/14
20140299820
 Graphene nanoparticles as conductive filler for resistor materials and a method of preparation patent thumbnailGraphene nanoparticles as conductive filler for resistor materials and a method of preparation
A composition of matter comprising graphene nano platelets, one or more ceramic fillers and, one or more high temperature fibers. In another embodiment, there is a flat sheet article comprising a calendered combination of graphene nano platelets, one or more ceramic fillers and, one or more high temperature fibers.
10/09/14
20140299364
 Electrically conductive article with high optical transmission patent thumbnailElectrically conductive article with high optical transmission
A transparent conductive article includes a transparent substrate, a thin electrically conductive grid, and a carbon nanolayer. The grid is disposed on the substrate, and the carbon nanolayer is also disposed on the substrate and in contact with the grid.
10/02/14
20140296530
 Indolizinone based derivatives as potential phosphodiesterase 3 (pde3) inhibitors and a process for the preparation thereof patent thumbnailIndolizinone based derivatives as potential phosphodiesterase 3 (pde3) inhibitors and a process for the preparation thereof
The present invention provides compounds of general formula a useful as potential phosphodiesterase3 (pde3) inhibitory agents and a process for the preparation thereof. The derivatives of formula a can be employed as therapeutics in human and veterinary medicine, where they can be used, for example, for the treatment and prophylaxis of the following diseases: heart failure, dilated cardiomyopathy, platelet inhibitors, cancer and obstructive pulmonary diseases..
10/02/14
20140296258
 Trisubstituted triazolopyrimidines for use in platelet aggregation inhibiton patent thumbnailTrisubstituted triazolopyrimidines for use in platelet aggregation inhibiton
The invention provides new triazolo[4,5-d]pyrimidine compounds, their use as medicaments, compositions containing them and processes for their preparation.. .
10/02/14
20140296224
 Quinoline derivatives as pi3 kinase inhibitors patent thumbnailQuinoline derivatives as pi3 kinase inhibitors
Invented is a method of inhibiting the activity/function of pi3 kinases using quinoline derivatives. Also invented is a method of treating one or more disease states selected from: autoimmune disorders, inflammatory diseases, cardiovascular diseases, neurodegenerative diseases, allergy, asthma, pancreatitis, multiorgan failure, kidney diseases, platelet aggregation, cancer, sperm motility, transplantation rejection, graft rejection and lung injuries by the administration of quinoline derivatives..
10/02/14
20140295555
 Method of culturing cells patent thumbnailMethod of culturing cells
A blood component such as platelets is concentrated. The concentrate, such as platelet-rich plasma, is used in a cell culture medium to grow and proliferate cells.
10/02/14
20140295402
 Methods and materials for prolonging useful storage of red blood cell preparations and platelet preparations patent thumbnailMethods and materials for prolonging useful storage of red blood cell preparations and platelet preparations
This document provides methods and materials for enhancing the storage capabilities of red blood cell preparations. For example, methods and materials for using co2 to store red blood cells in a manner that (a) reduces the level of glucose or 2,3-dpg consumption of or reduces the level of 2,3-dpg production by a red blood cell preparation, (b) reduces the level of lactate formation by a red blood cell preparation, and/or (c) reduces the ph level of a red blood cell preparation are provided.
10/02/14
20140294794
Methods for treating bleeding disorders using a platelet subpopulation
The present invention relates to a platelet subpopulation with high binding capacity to recombinant activated factor vii (rfviia), and its use for the treatment of bleeding disorders and for determining whether a subject is a candidate for treatment with rfviia.. .
10/02/14
20140293513
Graphene-based high voltage electrodes and materials
The disclosure describes an improved electrode with high voltage standoff characteristics and improved graphene-based materials and methods of making them for use therein. A graphene-based thin film material is described that may be applied or transferred to a current collector to create the improved electrode.
10/02/14
20140291227
Leukocyte filtration unit with reduced platelet adhesion
A filtration unit to selectively remove leukocytes from fluids containing platelets and systems including a filtration unit are provided. In one embodiment, a filtration unit is provided including an outer casing enclosing a porous element which includes a leukocyte-removal medium with a coating.
09/25/14
20140288142
Nitric oxide donor compounds
The invention relates to nitric oxide donor compounds and their use for treating cardiovascular diseases, inflammation, pain, fever, gastrointestinal disorders, ophthalmic diseases, hepatic disorders, renal diseases, respiratory disorders, immunological diseases, bone metobolisms dysfunctions, central and peripheral nervous system diseases, sexual dysfunctions, infectious diseases, for the inhibition of platelet aggregation and platelet adhesion, for treating pathological conditions resulting from abnormal cell proliferation, vascular diseases. The invention also relates to compositions comprising at least one nitric oxide releasing compounds of the invention and composition comprising at least one nitric oxide releasing compounds according to the invention and at least one 15 therapeutic agent..
09/25/14
20140288122
Method for inhibiting platelet aggregation
A method for inhibiting platelet aggregation in a patient in need thereof, comprising 1) administering to the patient a bolus injection of an active drug, in an amount of between about 25 μg/kg, and 2) administering to the patient, after the bolus injection, an intravenous infusion for a period of between about 12 hours and about 72 hours, of the active drug, in an amount of about 0.15 μg/kg/min, wherein the active drug is tirofiban or a salt thereof.. .
09/25/14
20140287903
Centrifuge
Centrifuges are useful to, among other things, remove red blood cells from whole blood and retain platelets and other factors in a reduced volume of plasma. Platelet rich plasma (prp) and or platelet poor plasma (ppp) can be obtained rapidly and is ready for immediate injection into the host.
09/25/14
20140287233
Platelet aggregation inducing substance
Wherein x represents pro or hyp; and n represents an integer of from 20 to 5,000.. .
09/25/14
20140284504
Apparatus and method for platelet monitoring and for assessing the quality of platelets
Apparatus and methods for monitoring platelet quality are disclosed. A bag of platelet concentrate is oriented in a desired manner on a transparent surface that is illuminated from one side with a light source.
09/18/14
20140277343
Drug delivery device, method, and system for administration of dual antiplatelet therapy
A drug delivery device for reducing the likelihood of stent thrombosis following implantation in a subject is provided. A stent is provided including a body having a plurality of struts and one or more coatings applied to the body including at least one polymer, a therapeutic agent for inhibiting restenosis, a loading dose of a first antiplatelet agent and a maintenance dose of the first antiplatelet agent, and a loading dose of a second antiplatelet agent and a maintenance dose of the second antiplatelet agent..
09/18/14
20140275269
Composition of 5-nitrobenzoate derivatives as anti-metastatic agent that inhibits tumor cell-induced platelet aggregation
And the preparation method therefor, wherein r is referred to hydrogen (h), unsubstituted, mono-substituted, di-substituted or tri-substituted benzoyl moiety. 5-nitrobenzoare derivatives of formula i do not affect the platelet aggregation, possesses the inhibitory activity related to the tumor cell-induced platelet aggregation (tcipa), and further specifically inhibits podoplanin-induced platelet aggregation.
09/18/14
20140274895
Methods and non-immunogenic compositions for treating inflammatory disorders
Methods for making non-immunogenic anti-inflammatory cytokine compositions, comprising (a) obtaining a liquid comprising cytokine producing cells from a mammalian donor; (b) contacting the liquid with a solid extraction material to generate a composition rich in interleukin-1 receptor antagonist; and performing one or both of (i) removing cells from the composition and (ii) freezing the composition. The compositions comprise two or more of il1-ra, stnf-r1, stnf-rii, igf-i, egf, hgf, pdgf-ab, pdgf-bb, vegf, tgf-β1, and sil-1rii, compositions may also contain white blood cells and platelets..
09/18/14
20140273064
Portable blood count monitor
This disclosure describes the development of a sample preparation, measurement, and analysis method that permits accurate characterization of red blood cells, platelets, and white blood cells, including a 3-part differential of the white blood cells count, to be performed on small volumes of a biological sample. This method is compatible with compact and portable instrumentation that permits the sample collection to be performed in a subject's home and analysis to be performed elsewhere by transmission of the data to a laboratory or doctor's office..
09/18/14
20140273061
Reagents, systems and methods for analyzing erythrocytes and platelets
Aspects of the invention include hematology analysis reagents, systems and methods that can be used to preserve blood cell morphology and integrity as well as provide sample integrity and optical clarity to facilitate optical analysis of blood samples. In some embodiments, the reagents include a non-phosphate organic buffer and a sphering surfactant.
09/18/14
20140271870
Treatment of pain using protein solutions
Methods for treating pain using a protein solution comprising two or more of il1-ra, stnf-r1, stnf-rii, igf-i, egf, hgf, pdgf-ab, pdgf-bb, vegf, tgf-β1, and sil-1rii, compositions may also contain white blood cells and platelets.. .
09/18/14
20140271863
Hot washable poly-n-isopropylacrylamide hydrogel delivery systems
The present disclosure is in the field of controlled release delivery of actives (e.g., drug-delivery, cosmeceutics, alternative medicine) though from an unusual and novel delivery vehicle: personal clothing. Means are disclosed for producing controlled-release systems well-suited not only for affixation to fabrics—e.g., clothing, bedding—but also for maintenance of active throughout washing cycles including hot-wash laundry cycles.
09/18/14
20140271816
Treatment of potential platelet aggregation with liposomally formulated glutathione and clopidogrel
The composition of the invention, liposomal glutathione in combination with clopidogrel has utility for improving the efficacy of clopidogrel in preventing the aggregation of platelet that can lead to clotting. The prevention of platelet aggregation has widespread utilization in many cardiovascular conditions such as coronary artery narrowing and more consistent “antiplatelet” activity is found with the invention, the combination of clopidogrel and liposomal reduced glutathione..
09/18/14
20140271625
Methods for treating bleeding disorders
Disclosed are methods for treating bleeding disorders, such as hemophilia, in subjects in need thereof by administering an antibody that specifically binds cd73. The methods reduce production of adenosine, increase platelet activation and/or enhance the level of coagulation on the platelet surface to reduce and/or stop bleeding.
09/18/14
20140271610
Collagen and alginate-based formulations for hemostasis
The present invention relates to composition(s) comprising collagen, calcium ions and alginate, wherein the composition polymerizes in situ when contacted with blood. The composition may further comprise an erythrocyte aggregation agent and/or a platelet activation agent.
09/18/14
20140271590
Methods for production of platelets from pluripotent stem cells and compositions thereof
Methods for production of platelets from pluripotent stem cells, such as human embryonic stem cells (hescs) and induced pluripotent stem cells (ipscs) are provided. These methods may be performed without forming embryoid bodies or clusters of pluripotent stem cells, and may be performed without the use of stromal inducer cells.
09/18/14
20140271588
Treatment of peripheral vascular disease using protein solutions
Methods of treating peripheral vascular disease comprising administering a protein solution site of a defect at least two proteins from the group il-1ra, stnf-ri, stnf-rii, igf-i, egf, hgf, pdgf-ab, pdgf-bb, vegf, tgf-β1, and sil-1rii. The solution may also comprise white blood cells, platelets, concentrated bone marrow aspirate, and combinations thereof..
09/18/14
20140270458
Portable blood count monitor
Devices, systems, and methods are disclosed for determining the number and type of blood cells in a blood sample. The blood sample is collected and held in a slide.
09/18/14
20140263035
Method for forming perforated graphene with uniform aperture size
A method of forming a filter with uniform pore sizes includes synthesizing a moiety so as to form a plurality of like platelets having a precisely sized pore extending therethrough, distributing the plurality of like platelets about a membrane having apertures therethrough, and bonding the plurality of platelets around the apertures to form precisely sized pores through the membrane. A filtration membrane is also disclosed which provides a porous membrane having a plurality of apertures therethrough, and a plurality of platelets, wherein each platelet has a pore therethrough.
09/11/14
20140256866
Synthetic megakalsilite via hydrothermal preparation
This invention relates to megakalsilite platelets, methods of hydrothermally forming said platelets and the megakalsilite platelets obtainable via the disclosed hydrothermal method. More specifically the disclosure describes an improved hydrothermal synthesis of megakalsilite platelets, which are suitable as platelet for interference pigments, and in barrier and flame retardant applications..
09/11/14
20140256033
Devices for determining cell force properties and methods of manufacturing the devices
A device may be configured to allow individual measuring of at least one property of at least one cell, such as measuring a contraction force of a platelet. The device may include a plurality of wells.
09/11/14
20140255908
Apparatus, systems, and methods for processing platelets and contaminated blood
One aspect of the present disclosure relates to a bag for storing platelets or contaminated blood previously withdrawn from a subject. The bag can comprise a flexible, closed container and at least one removable heat transfer member adhered to an outer surface portion of the container.
09/11/14
20140255785
Silicon-graphene nanocomposites for electrochemical applications
A nanographitic composite for use as an anode in a lithium ion battery includes nanoscale particles of an electroactive material; and a plurality of graphene nanoplatelets having a thickness of 0.34 nm to 5 nm and lateral dimensions of less than 900 nm, wherein the electroactive particle has an average particle size that is larger than the average lateral dimension of the graphene nanoplatelets, and the graphene nanoplatelets coat at least a portion of the nanoscale particles to form a porous nanographitic layer made up of overlapping graphene nanoplatelets.. .
09/11/14
20140255529
Method for preventing and treating thrombotic disorders using a pharmaceutical composition comprising an extract of lindera obtusiloba
A method for preventing and treating thrombotic disorders in a subject in need thereof comprising, administering a pharmaceutical composition comprising an extract of lindera obtusiloba as an active ingredient to the subject. A pharmaceutical composition and a health functional food for preventing and treating thrombotic disorders by improving blood circulation, comprising an extract of lindera obtusiloba as an active ingredient.
09/11/14
20140255328
Hydrothermal synthesis of zinc phlogopite
This invention relates to a synthetically derived zinc phlogopite platelets, of superior platelet diameter, effect pigments comprising such synthetically derived platelets and methods of forming said substrates. More specifically the disclosure describes an improved hydrothermal synthesis of zinc phlogopite suitable as a platelets for interference pigments, barrier and flame retardant applications..
09/11/14
20140251184
Synthetic zinc phlogopite via hydrothermal preparation
This invention relates to synthetically derived zinc phlogopite platelets, of superior aspect ratio, effect pigments comprising such synthetically derived platelets and methods of forming said platelets. More specifically the disclosure describes an improved hydrothermal synthesis of zinc phlogopite suitable as a platelets for interference pigments, barrier and flame retardant applications..
09/04/14
20140248290
Inhibition of cancer metastasis
P-selectin on platelets and endothelium binds cell surface chondroitin sulfate (cs) proteoglycans, which are abundantly and stably expressed on the surface many cancer cells. Binding of the cancer cells through the cs moieties may be blocked to inhibit the interaction of cancer cells with platelets and endothelium.
09/04/14
20140246628
Conductive polymer material, use of same, and a method for the production of same
The invention relates to a conductive elastomer provided and formed from a base elastomer and conductive solid particles that are distributed therein. The conductive particles used are: a) platelet-shaped conductive particles and/or b) dendritic conductive particles and/or c) other elongated conductive particles with a length:width ratio of greater than or equal to two.
08/28/14
20140243502
Anticoagulation agent and uses thereof
The present invention provides an anticoagulant agent including a first element capable of inhibiting coagulation and a second element capable of targeting an activated platelet wherein upon administration of the agent to a subject the second element directs the first element to the activated platelet. Also provided is a probe for detecting a blood vessel abnormality including (a) a binding element capable of targeting an activated platelet and (b) a label.
08/28/14
20140242262
Carbon-based electrodes with graphene modification
Certain embodiments of the present application describe a carbon-based electrode with graphene platelets. The addition of graphene platelets is intended to improve properties of the electrode.
08/28/14
20140242054
Methods and compositions for treating respiratory conditions using platelet enriched plasma
Described herein are methods and compositions for the treatment of respiratory diseases such as, for example, exercise induced pulmonary hemorrhage. The methods include the use of compositions comprising platelet enriched plasma, for example, platelet rich plasma and/or platelet poor plasma, for treatment of respiratory diseases in humans and animals, in particular, equines, by administration to the respiratory system..
08/28/14
20140241957
Tube to produce platelet rich fibrin
Invention; it is about the tubes used to obtain blood products through centrifuge order to cure open and closed injuries, to heal hard and soft tissues and to diagnose in all fields of medicine and dentistry. Platelet rich fibrin (prf) obtained in the tubes the surface of which contacts blood and made from pure titanium or titanium alloys has a better structure of fibrin than that is obtained through classical methods.
08/21/14
20140235868
Novel antithrombotic and antiatherosclerotic agent and method for producing same (variants)
The use of 2-[2-cyano-2-[5-(hydroxymethyl)-3-methyl-1,3-oxazolidin-2-ylidene]ethylidene]indolin-3-one of formula i is proposed as a biologically active compound exhibiting the properties of exogenous nitric oxide donor, a platelet aggregation inhibitor, also exhibiting antihypertensive activity and activating activity towards the soluble guanylate cyclase enzyme. Variants of methods for synthesizing the above compound are also proposed..
08/21/14
20140235827
Mouse anti-aggrus monoclonal antibodies
The present invention provides a monoclonal antibody or a functional fragment thereof, capable of recognizing aggrus epitope comprising an amino-acid sequence represented by a sequence id 1, 3, or 4, and the monoclonal antibody or the functional fragment thereof produced from a hybridoma with deposit id of ferm bp-11446, ferm bp-11447, ferm bp-11448 or ferm bp-11449. The present invention provides the hybridoma, and further an aggrus-clec-2 binding inhibitor and a pharmaceutical composition for inhibition of platelet aggregation, prevention of cancer metastasis, or treatment of tumor or cancer, comprising the monoclonal antibody or the functional fragment thereof..
08/21/14
20140234859
Controlled platelet activation to monitor therapy of adp antagonists
A method is provided of determining whether an individual has reduced ability to form platelet thrombi due to inhibition of platelet activation initiation, signal transduction and/or gpiib/iiia blockade. A blood sample is obtained from the individual being assessed.
08/21/14
20140234322
Thrombopoietin mimetics for the treatment of radiation or chemical induced bone marrow injury
Disclosed are transgenic non-human mammals, which useful for the screening of thrombopoietin mimetics, thrombopoietin receptor agonists, or thrombopoietin receptor antagonists active on the human thrombopoietin receptor. The transgenic non-human mammal has a genome that comprises a stably integrated transgene construct comprising a polynucleotide sequence encoding a humanized thrombopoietin receptor wherein said transgenic non-human mammal has a baseline blood platelet count corresponding to a physiological blood platelet count of a matched non-transgenic non-human mammal.


Popular terms: [SEARCH]

Platelet topics: Growth Factor, Fibroblast, Nanoparticle, Autologous, Leukocytes, Circulation, Transforming Growth Factor, Therapeutical, Platelet Derived Growth Factor, Bone Morphogenetic Protein, Endothelial, Recombinant, Stem Cells, Respiratory System, Dispensing System

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This listing is a sample listing of patent applications related to Platelet for is only meant as a recent sample of applications filed, not a comprehensive history. There may be associated servicemarks and trademarks related to these patents. Please check with patent attorney if you need further assistance or plan to use for business purposes. This patent data is also published to the public by the USPTO and available for free on their website. Note that there may be alternative spellings for Platelet with additional patents listed. Browse our RSS directory or Search for other possible listings.
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