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Platelet-related patent applications - as published by the U.S. Patent and Trademark Office (USPTO).


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NEW Pericyte long non-coding rnas
Johann Wolfgang Goethe-universität Frankfurt Am Main
February 15, 2018 - N°20180044672

The present invention provides novel non-coding rnas (lncrna) that were identified to be expressed in pericytes upon hypoxia. The lncrna of the invention positively affect platelet-derived growth factor receptor (pdgfr) beta expression, pericytes proliferation and pericyte recruitment to endothelial cells. The invention provides inhibitors of the lncrna for use in the treatment of diseases mediated by pdgfr expression. For example ...
NEW Method for producing culture containing megakaryocytes, and method for producing platelets using same
Kyoto University
February 15, 2018 - N°20180044634

The present invention provides a method for producing megakaryocytes that have an increased capacity to produce platelets, the method comprising a step of culturing, under conditions that cause the death of cells that do not express a gene that is specifically expressed by megakaryocytes, cells that have the capacity to differentiate into megakaryocytes.
NEW Cell preparations for extemporaneous use, useful for healing and rejuvenation in vivo
February 15, 2018 - N°20180042964

The present invention relates to new plasma or new platelet-rich plasma preparations, new cell dissociation methods, new cell associations or compositions, a method of preparation thereof, a use thereof, devices for the preparation thereof and preparations containing such a platelet-rich plasma preparation and cell associations or compositions. Specifically, the invention provides plasma or platelet-rich plasma alone or in cell combinations ...
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Platelet Patent Applications
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Cell preparations for extemporaneous use, useful for healing and rejuvenation in vivo
February 08, 2018 - N°20180036346

The present invention relates to new plasma or new platelet-rich plasma preparations, new cell dissociation methods, new cell associations or compositions, a method of preparation thereof, a use thereof, devices for the preparation thereof and preparations containing such a platelet-rich plasma preparation and cell associations or compositions. Specifically, the invention provides plasma or platelet-rich plasma alone or in cell composition ...
Benzothiazole and benzothiophene compounds
Universite De Montreal
February 08, 2018 - N°20180036287

The present invention provides benzothiazole compounds or benzothiophene compounds of formula i having the structure: wherein x1, x2, x3, x4, x5, y, wr2, r3, r4, r5, r6, r7 and aa and other moieties are as defined herein, or a stereoisomer, tautomer, pharmaceutically acceptable salt, prodrug ester or solvate form thereof. These compounds are inhibitors of platelet aggregation and thus can ...
Platelet test chip
Korea University Research And Business Foundation
February 01, 2018 - N°20180031540

Disclosed is a platelet-testing chip. The platelet-testing chip includes a plurality of sample chambers storing blood samples, stirrers provided in the sample chambers to apply shearing force to the blood samples, a plurality of waste sample chambers provided so as to correspond to the plurality of the sample chambers, microchannels, through which the sample chambers and the waste sample chambers ...
Platelet Patent Pack
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Platelet Patent Applications
Download 244+ Platelet-related PDFs
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inventor
  • 244+ full patent PDF documents of Platelet-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
Pyrazolyl substituted carbonic acid derivatives as modulators of the prostacyclin (pgi2) receptor useful for the ...
Arena Pharmaceuticals, Inc.
February 01, 2018 - N°20180030039

Pyrazole derivatives of formula ia and pharmaceutical compositions thereof that modulate the activity of the pgi2 receptor. Compounds of the present invention and pharmaceutical compositions thereof are directed to methods useful in the treatment of: pulmonary arterial hypertension (pah) and related disorders; platelet aggregation; coronary artery disease; myocardial infarction; transient ischemic attack; angina; stroke; ischemia-reperfusion injury; restenosis; atrial fibrillation; blood ...
Methods and compositions for treatment of penile defects
February 01, 2018 - N°20180028575

Compositions for use in treating penile defects, including erectile dysfunction and peyronie's disease. Compositions include penile stem cells and isolated penile stem cells substantially free of red blood cells, additives such as amnion, amniotic fluid, extracellular matrix components, growth factors, anti-inflammatories, antioxidants, wound healing agents, and collagenases. Also provided are methods of treating said penile defects in a patient, including ...
Platelet concentrate for increase of cell regeneration and cell growth
January 25, 2018 - N°20180021377

The invention refers to a decomposed platelet concentrate containing ≦50% intact platelets and optionally ≧200 pg/ml rantes and specifically to its use in the prevention or treatment of hair loss and/or for promoting hair growth. The invention further refers to a composition comprising the decomposed platelet concentrate and body fat cells and the use of said composition for ...
Method for producing polyploidized megakaryocyte and platelets
The University Of Tokyo
January 18, 2018 - N°20180016597

An object of the present invention is to provide a method of promoting polyploidization of megakaryocytes and thereby producing highly polyploidized megakaryocytes, a method of efficiently producing platelets from polyploidized megakaryocytes, and the like. The present invention provides a method of producing polyploidized megakaryocytes comprising a step of forcing expression of an apoptosis suppressor gene in megakaryocytes before polyploidization and ...
Matrix in ball form as a cell carrier
Maco Pharma
January 18, 2018 - N°20180015147

The invention relates to a matrix in ball form comprising cross-linked fibrinogen, the matrix being free from fibrin, as well as to a method for preparing such a matrix, comprising the following steps: (a) providing an initial composition comprising fibrinogen and a platelet factor, (b) injecting said initial composition into an oil heated to a temperature of 50° c. To 80&#...
Platelet targeted treatment
Platelet Targeted Therapeutics, Llc
January 11, 2018 - N°20180009874

The present disclosure relates to compositions and methods for targeting expression of exogenous genes to platelets. In particular, the present disclosure relates to treatment of hemophilia and other diseases and conditions by targeting expression of exogenous agents (e. G., clotting factors) to platelets.
Column-based device and method for retrieval of rare cells based on size, and uses thereof
Agency For Science, Technology And Research
January 11, 2018 - N°20180008982

A column-based device and method for retrieving cells of interest were enclosed. The said device comprises a column comprising (i) an inner wall defining an inner chamber with inlet and outlet openings, (ii) a perforated plug disposed adjacent to the outlet opening, (iii) a sleeve insert with a channel and disposed within the chamber and adjacent to the perforated plug, ...
Platelet Patent Pack
Download 244+ patent application PDFs
Platelet Patent Applications
Download 244+ Platelet-related PDFs
For professional research & prior art discovery
inventor
  • 244+ full patent PDF documents of Platelet-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
Unit aerosol doses for anticoagulation
The Regents Of The University Of California
January 11, 2018 - N°20180008540

Disclosed herein are methods for prophylactic treatment of acute coronary syndrome (acs) comprising administering, by inhalation, an effective amount of a pharmaceutical composition comprising at least one anticoagulant or antiplatelet agent to a subject in need thereof, wherein the anticoagulant or antiplatelet agent first enters the heart via the left atrium.
Antiplatelet agent and uses thereof
January 04, 2018 - N°20180000750

Disclosed herein are methods for suppressing or inhibiting platelet aggregation in a subject in need thereof. The method includes administering to the subject in need thereof an effective amount of physalin to alleviate or ameliorate symptoms associated with diseases, disorders, and/or conditions resulted from platelet aggregation. According to preferred embodiments, physalin is applied as a coating on an implantable ...
Apparatus and method for producing augmentive products
January 04, 2018 - N°20180000596

An apparatus for shaping a platelet rich fibrin component of patient whole blood includes a main body. The main body includes a substantially planar surface. The main body also has a reservoir positioned therein. The substantially planar surface includes a plurality of channels fluidly connecting the substantially planar surface and the reservoir. The apparatus also includes a lid which is ...
Platelet protection solution having beta-galactosidase and sialidase inhibitors
The Brigham And Womens Hospital Inc
January 04, 2018 - N°20180000066

The present invention relates to a platelet protection solution (pps) having an amount of one or more β-galactosidase inhibitors with or without an amount of one or more sialidase inhibitors, and optionally one or more glycan-modifying agents; and one or more of pps components that include a salt, a citrate source, a carbon source, or any combination thereof.
Reconstitution solution for spray-dried plasma
The Government Of The United States
December 28, 2017 - N°20170370952

The present invention relates to a reconstitution solution for spray dried plasma having a non-anticoagulant compound that does not bind calcium. When the reconstitution solution of the present invention is mixed with spray dry plasma, the reconstituted plasma mediates platelet adhesion and aggregation about the same as or greater than the starting plasma prior to spray drying. The present invention ...
Elastomeric materials
Schlumberger Technology Corporation
December 28, 2017 - N°20170370174

A bore tool can include a component that includes a longitudinal axis and a perimeter surface disposed at one or more radii from the longitudinal axis; and an elastomeric component disposed about the perimeter surface where the elastomeric component includes an elastomeric material that includes carbon-based nanoplatelets.
Methods for isolation of platelets
Anthrogenesis Corporation
December 28, 2017 - N°20170369845

Provided herein are methods for the isolation of platelets, for example, isolation of platelets from umbilical cord blood. In certain embodiments, presented herein are methods for preparation of platelet rich plasma. In one aspect, provided herein are methods for isolation of platelets from blood. In certain embodiments, presented herein are methods for isolation of platelets from cord blood, e. G., ...
Methods of controlling polymorphism in organic-free synthesis of na-zeolites and zeolite crystals formed therefrom
University Of Houston System
December 28, 2017 - N°20170369327

Methods of controlling crystal polymorphism in organic-free synthesis of na-zeolites and the zeolite crystals formed using those methods are provided. The methods disclosed herein create certain types of zeolite crystals more efficiently than other previously known methods. The methods also create certain types of zeolite crystals in a form and concentration not previously disclosed. The methods disclosed herein generally comprise ...
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