 Patent Application Title |
Patent App Num. |
Date |
| Method of maintaining or improving the skin health of an animal comprising administering as a dietary supplement a composition comprising flax seed oil and gamma linolenic acid | 20130116314 | 20130509 |
 A phytochemical composition for use as a veterinary dietary supplement comprising alpha linolenic acid (ALA) and up to 10% gamma linolenic acid (GLA). Preferably the ALA source is flax seed oil and GLA is sourced from borage oil.
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| Composition and method of delivery of l-arabinose and select compounds | 20130108586 | 20130502 |
 The disclosure relates to dietary supplement compositions comprising L-arabinose and one or more select compounds, which may include one or more select phytochemical compounds. The claimed compositions are useful in dietary supplements to facilitate mitigating elevated blood sugar levels and managing a user's weight as well as enhancing performance of digestive system to prevent inflammation and infection.
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| Stabilized, biocompatible gold nanoparticles | 20130084248 | 20130404 |
 The invention provides stabilized, biocompatible gold nanoparticles that are stabilized with material from polyphenols- or flavanoids-rich plant material or reactive phytochemical components of the plant material. The gold nanoparticles of the invention can be fabricated with an environmentally friendly method for making biocompatible stabilized gold nanoparticles. In preferred embodiments, the coating consists of material from polyphenols- or flavanoids-rich plant material or reactive phytochemical components of the plant material.
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| Synergistic phytochemical composition and a process for preparation thereof | 20130053339 | 20130228 |
 The present invention also provides a process for preparing the composition.
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| Exosomal compositions and methods for the treatment of disease | 20120315324 | 20121213 |
 An exosomal composition is provided that comprises a therapeutic agent encapsulated by an exosome. The therapeutic agent can be a phytochemical agent, a chemotherapeutic agent, or a Stat3 inhibitor. Pharmaceutical compositions comprising the exosomal compositions are also provided. Methods for treating an inflammatory disease or a cancer are further provided and include administering an effective amount of an exosomal composition to a subject in need thereof to thereby treat the inflammatory disorder or the cancer.
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| Methods and compositions related to regulation of cytokine production by glycogen synthase kinase 3 (gsk-3) | 20120309808 | 20121206 |
| Provided herein are pharmaceutical compositions and methods for treating disorders characterized by reduced expression of anti-oxidative stress enzymes in a subject. In one aspect, the present invention provides a method for inducing expression of anti-oxidative stress enzymes in a subject in need thereof. The method includes administering to the subject a therapeutically effective amount of a demethylating agent. The demethylating agent includes a phytochemical that induces expression of Nrf2 and Nrf2-mediated genes expressing anti-oxidative stress. Such phytochemicals include indoles, such as 3,3′-diindolylmethane (DIM) and indole-3-carbinol (I3C), and isothiocyanates, such as phenethyl isothiocyanate (PEITC) and sulforaphane (SFN).
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| novel boswellia low polar gum resin extract and its synergistic compositions | 20120301432 | 20121129 |
| The present disclosure describes Boswellia low polar gum resin extract (BLPRE) comprising novel phytochemical composition of sesquiterpenes, diterpenes, triterpenes and other phytochemical(s) obtained from gum resin of Boswellia species. The present disclosure also describes compositions comprising BLPRE in combination with one or more component(s) selected from biologically active ingredient(s), functional ingredient(s), excipient(s), diluents(s), carrier(s) and additive(s) or mixtures thereof. Further the present disclosure also provides synergistic composition(s) comprising Boswellia low polar gum resin extract (BLPRE) and at least one component selected from but not limited to extract(s), fraction(s), phytochemical(s) or their salts or mixtures thereof derived from Boswellia species or Curcuma species.
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| Methods and compositions for controlled delivery of phytochemical agents | 20120231079 | 20120913 |
| Compositions are provided that comprises a biocompatible polymeric matrix incorporating an effective amount of a phytochemical agent, a combination of phytochemical agents, or a phytochemical agent and one or more additional therapeutic agents. Methods of treating a cancer using the compositions are further provided.
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| Agents derived from holoptelea integrifolia and their compositions for the control of metabolic syndrome and associated diseases | 20120231095 | 20120913 |
| The invention discloses phytochemical agents derived from Holoptelea integrifolia and novel composition(s) comprising at least one component selected from the extract(s), fraction(s) and active compound(s) for the protection and alleviation of Metabolic Syndrome, insulin resistance, endothelial dysfunction, chronic kidney disease, atherosclerosis, diabetes and other disease conditions associated with metabolic syndrome. The invention also discloses the amelioration of certain biomarker molecules such as Peroxisome proliferator-activated receptor gamma (PPAR-γ), Adipose Differentiation Related Protein (ADRP), CD36, Adipocyte Fatty-acid-Binding Protein (aP2/FABP-4/A-FABP), beta-3 Adrenergic Receptor (β3AR), Leptin, Perilipin and Adiponectin by using the phytochemical components derived from Holoptelea integrifolia.
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| Phytochemical compositions including sesamin for anti-inflammatory, anti-cytokine storm, and other uses | 20120178712 | 20120712 |
| A composition (e.g., phytochemical composition) including sesamin, the composition exhibiting anti-inflammatory, anti-cytokine storm, connective tissue preservation, anti-viral, and/or other properties in biological tissue. The phytochemical composition therapeutically affects a pro-inflammatory cytokine condition, for instance facilitating or effectuating decrease in a quantity of a pro-inflammatory cytokine, for example, interleukin-1 and tumor necrosis-alpha. The phytochemical composition facilitates or effectuates an increase in quantity of an anti-inflammatory cytokines. The phytochemical composition can additionally facilitate a connective tissue extracellular matrix (ECM) preservation effect. The phytochemical composition can also inhibit an action of a viral neuraminidase, for example, the influenza A virus neuraminidase. Uses of sesamin for the manufacture of phytochemical compositions having predetermined concentrations of sesamin include one or more of facilitating a decrease in quantity of pro-inflammatory cytokines, an... |
| Phytochemical compositions including xanthones for anti-inflammatory, anti-cytokine storm, and other uses | 20120172329 | 20120705 |
| A composition (e.g., a phytochemical composition) including a predetermined concentration of xanthones, and in certain embodiments predetermined concentrations of both xanthones and sesamin. The composition facilitates at least one of decreasing pro-inflammatory cytokines, increasing anti-inflammatory cytokines, enhancing a connective tissue anti- degeneration effect, and inhibiting viral neuraminidase (e.g. neuraminidase of an influenza A virus). The composition can further decrease at least one of gene expression and release of pro-inflammatory cytokines. The phytochemical composition can increase at least one of gene expression and release of anti-inflammatory cytokines. The phytochemical composition provides at least one of an anti-inflammatory, an anti-viral (e.g., anti-influenza), and a connective tissue anti-degradation effect in a living organism. A use of xanthones for manufacturing phytochemical compositions that include predetermined concentrations of xanthones is also... |
| Compositions and methods for attracting noctuid moths | 20120107266 | 20120503 |
| The invention provides compositions for attracting noctuid moths, which include at least one pheromone and at least one synergist. The synergist is a naturally-occurring phytochemical compound. The synergist is preferably β-caryophyllene, iso-caryophyllene, α-humulene, or combinations thereof. The invention also provides traps containing the composition for attracting noctuid moths, and methods for attracting, capturing, killing or sterilizing noctuid moths using the composition.
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| Mucositis prevention supplement and treatment | 20120087991 | 20120412 |
| The present invention provides for a nutritional composition comprising from 0.25 g to 25 g of glutamine, in neutral or salt form or precursor or derivative thereof; and from 0.1 g to 10 g of a phytochemical or a mixture thereof, wherein the phytochemical is an antioxidant. The nutritional composition is particularly useful in the treatment and/or prevention of mucositis.
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| Anti-biofilm compositions and methods for using | 20120088671 | 20120412 |
| The present invention provides polyphenolic compositions derived from a plant that inhibit the formation of a biofilm. Also provided are combinations that comprise at least one phenolic phytochemical and at least one antimicrobial agent that inhibit the growth of an established biofilm. Further, the present invention provides methods for inhibiting the formation and growth of biofilms.
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| Compositions and methods for enhanced attraction of noctuid moths | 20120034288 | 20120209 |
| The invention provides compositions for attracting noctuid moths, which include at least one pheromone and at least one enhancer. The enhancer is a naturally-occurring phytochemical compound. The enhancer is preferably trans-2, cis-6-nonadienal. The invention also provides lures and traps containing the composition for attracting noctuid moths, and methods for attracting, capturing, killing or sterilizing noctuid moths using the composition.
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| Feminine fresh all day | 20120006715 | 20120112 |
| Additionally, a pleasant residual fragrance from this product can be well appreciated with use.
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| Compositions and methods for detoxification and cancer prevention | 20120003340 | 20120105 |
| Nutritional compositions capable of reducing the risk of cancer are provided. The nutritional compositions combine the added effects of both a probiotic source and a phytochemical(s) capable of inducing enzymatic activity in mammals to reduce the incidence of cancer. The probiotic and phytochemical source can be derived from a single plant material, such as chicory.
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| Compositions and methods for extracting and using phytochemicals for the treatment of influenza | 20100298250 | 20101125 |
| Methods and compositions for treating at least one symptom of a viral infection, said method of treatment comprising administering to a subject with a least one symptom of a viral infection an effective dosage unit of a composition comprising pomegranate extract. The compositions comprise pomegranate extract comprising polyphenols. The composition is produced by a process comprising providing one or more pomegranate solids selected from the group consisting of a pericarp, inner membrane and seeds, creating a mixture comprising said one or more pomegranate solids in an aqueous solution, heating said mixture to a temperature that permits enzyme catalysis of said pomegranate solids, and removing residual insoluble solid materials from said mixture to provide said pomegranate extract. Compositions containing the extract may be used as a food... |
| Process for the manufacture of sugar and other food products | 20100285186 | 20101111 |
| A process for manufacturing of sugar products having desired levels of specific phytochemicals comprising the steps of: preparing a primary sugar product; analysing said primary sugar product for its phytochemical profile using an analytical method selected from the group consisting of near infrared spectroscopy, electrical conductivity, and combinations thereof; comparing said profile; treating said primary sugar product, if required, to achieve a final sugar product having desired levels of specific phytochemicals.
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| Mucositis prevention supplement and treatment | 20100255119 | 20101007 |
| The present invention provides for a nutritional composition comprising from 0.25 g to 25 g of glutamine, in neutral or salt form or precursor or derivative thereof; and from 0.1 g to 10 g of a phytochemical or a mixture thereof, wherein the phytochemical is an antioxidant. The nutritional composition is particularly useful in the treatment and/or prevention of mucositis.
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| Synergistic combinations for treating hypertension | 20100233256 | 20100916 |
| The present invention relates to methods and compositions effective in lowering blood pressure. The compositions comprise, as active ingredients, an effective amount of a combination of lycopene and a carotenoid, e.g., lutein. In a preferred embodiment, the lycopene and lutein together provide a synergistic therapeutic effect at lowering blood pressure. The compositions can further comprise additional agents such as carotenoids and other phytochemicals found in tomato oleoresin.
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| New synergistic phytochemical composition for the treatment of obesity | 20100227828 | 20100909 |
| Synergistic anti-adipogenic and pro-lipolytic compositions for the prevention and amelioration of adipogenesis and lipolysis mediated diseases, comprising at least two extracts selected from enriched demethylated curcuminoids obtained from Curcuma longa, Moringa oleifera and Murraya koenigii. The anti-adipogenic and pro-lipolytic compositions optionally contain one or more anti-obesic agents. These compositions are useful for preventing anti-inflammatory and free radical mediated diseases.
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| Cancer cell growth inhibition by black bean (phaseolus vulgaris l) extracts | 20100216729 | 20100826 |
| A group of phytochemical compounds extracted from whole germinated or not germinated black beans (Phaseolus vulgaris L) and/or their dry milled fractions such as seed coats or hulls and cotyledons is described. These phytochemicals are classified as phenolics, such as polyphenols, flavonoids, coumarins, and tannins, triterpenes such as saponins, phytosterols and other antioxidant compounds that proved to be effective to decrease cancer proliferation of hormone dependent mammary (MCF-7), hormone independent hepatic (HepG2) and colon (Caco2) cancer cells. They also effectively protect against chemical damage induced with DMBA and furthermore prevented cancer induced by this chemical in Wistar rats and also reduced tumor size when consumed after tumor detection. Methanol, acetone, ethanol, water and mixtures of these solvents were used to obtain the extracts from raw, cooked,... |
| Novel mitochondrial uncoupling methods and compositions for enhancing adipocyte thermogenesis | 20100215782 | 20100826 |
| Disclosed are methods, compounds, and compositions comprising botanically based drugs, medical foods, and dietary supplements for the prevention and treatment of metabolic disorders, in particular obesity, weight gain, insulin resistance syndromes, diabetes, fasting hyperlipidemia and osteoarthritis. More specifically, the invention relates to pharmaceutical therapeutic methods and compositions utilizing phytochemicals, natural plant extracts and combinations to modify adipocyte physiology to enhance thermogenesis and modify cytokine secretion.
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| Phytochemical-rich oils and methods related thereto | 20100197643 | 20100805 |
| The invention relates to methods used in extracting oil from plants, plant fruits, and/or nuts, preferably fruits from plants of the family Arecaceae, or Palmae, even more preferably acai fruit. In some embodiments, the invention relates to methods of extracting the oil using an extraction solution comprising a volatile alcohol and volatile ketone. In other embodiments, the invention relates to oil from acai fruit and acai fruit by-products that contain enriched concentrations of phytochemicals.
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| Microencapsulated citrus phytochemicals comprising citrus limonoids and application to sports drinks | 20100196577 | 20100805 |
| Methods are disclosed for fortifying a sports drink with one or more citrus phytochemicals while concealing the bitter taste of these compounds in the beverage. These methods comprise microencapsulating the citrus phytochemicals and adding the microencapsulated citrus phytochemicals to the beverage. Also disclosed are sports drinks fortified with one or more microencapsulated citrus phytochemicals but which do not have the bitter taste characteristics of these compounds.
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| Microencapsulated citrus phytochemicals comprising citrus limonoids and application to beverages | 20100196554 | 20100805 |
| Methods are disclosed for fortifying a beverage with one or more citrus phytochemicals while concealing the bitter taste of these compounds in the beverage. These methods comprise microencapsulating the citrus phytochemicals and adding the microencapsulated citrus phytochemicals to beverages. Also disclosed are beverages fortified with one or more microencapsulated citrus phytochemicals but which do not have the bitter taste characteristics of these compounds.
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| Microencapsulated citrus phytochemicals and application to sports drinks | 20100196549 | 20100805 |
| Methods are disclosed for fortifying a sports drink with one or more citrus phytochemicals while concealing the bitter taste of these compounds in the beverage. These methods comprise microencapsulating the citrus phytochemicals and adding the microencapsulated citrus phytochemicals to the beverage. Also disclosed are sports drinks fortified with one or more microencapsulated citrus phytochemicals but which do not have the bitter taste characteristics of these compounds.
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| Microencapsulated citrus phytochemicals and application to beverages | 20100196543 | 20100805 |
| Methods are disclosed for fortifying a beverage with one or more citrus phytochemicals while concealing the bitter taste of these compounds in the beverage. These methods comprise microencapsulating the citrus phytochemicals and adding the microencapsulated citrus phytochemicals to beverages. Also disclosed are beverages fortified with one or more microencapsulated citrus phytochemicals but which do not have the bitter taste characteristics of these compounds.
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| Cachexia prevention supplement | 20100189816 | 20100729 |
| The invention provides for a nutritional composition comprising from 0.1 to 10 g of eicosapentaenoic acid or a derivative thereof based on 100 kcal of the total composition; and from 0.1 to 10 g of a phytochemical or a mixture thereof based on 100 kcal of the total composition, for a use as a medicament for the treatment and/or prevention of cachexia and/or anorexia. The composition is particularly useful in the prevention of cachexia and is administered almost without any additional macronutrients in order to avoid a negative impact on the general diet of the patient.
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| Methods of making pomegranate compounds for the treatment of erectile dysfunction | 20100173029 | 20100708 |
| Various processes for producing an extract containing phytochemicals from pomegranates are disclosed. The processes generally comprise providing pomegranate solids, such as the pericarp, inner membrane and seeds; creating a mixture comprising the pomegranate solids in an aqueous solution; adding enzymes to the mixture in an amount sufficient to at least partially degrade the pomegranate solids; heating the mixture to a temperature that permits the maximum rate of catalysis of the enzyme; maintaining the temperature of the heated mixture for a time sufficient to allow at least partial degradation of the pomegranate solids; and removing residual insoluble solid materials from the mixture. Compositions containing the extract may be used as a food product, beverage, pharmaceutical preparations, nutritional supplements, vitamin supplements, food additives, and food supplements. The compositions... |
| Flavonoid-rich citrus extract and compositions thereof | 20100159100 | 20100624 |
| Flavonoid citrus extract and compositions thereof are provided, wherein the flavonoid citrus extract is derived from the by-product of a citrus extraction process. The flavonoid citrus extract and compositions are especially beneficial as a source for providing important phytochemicals, like flavonoids, which are biologically active in humans. In a particular application, the citrus extract is an orange juice product, which can be added to citrus based beverages, non-citrus based beverages or used as a stand alone juice.
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| Antimicrobial efficacy of aframomum melegueta extract against propionibacterium acnes | 20100112105 | 20100506 |
| The use of compositions containing one or more phytochemicals such as gingerols, paradols, and mixtures thereof for aiding in the control, reduction or elimination of Propionibacterium acnes. Aframomum melegueta extracts containing the one or more phytochemicals can be used against P. acnes to effect the growth of the bacterium on a surface.
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| Phytochemical compositions and methods for activating amp-kinase | 20100112099 | 20100506 |
| The present invention relates to AMPK activation utilizing phytochemicals, natural plant extracts and combinations. Disclosed are methods, compounds, and compositions comprising drugs, medical foods, and dietary supplements for the prevention and treatment of metabolic disorders, in particular obesity, weight gain, insulin resistance syndromes, diabetes, fasting hyperlipidemia and osteoarthritis. More specifically, the invention relates to pharmaceutical therapeutic methods and compositions utilizing phytochemicals, natural plant extracts and combinations to modify myocyte, hepatocyte, adipocyte, cardiac or pancreatic physiology through activation of AMPK.
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| Composition | 20100087533 | 20100408 |
| A phytochemical composition for use as a veterinary dietary supplement comprising alpha linolenic acid (ALA) and up to 10% gamma linolenic acid (GLA). Preferably the ALA source is flax seed oil and GLA is sourced from borage oil.
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| Treatment apparatus for plant matter | 20100043287 | 20100225 |
| Treatment apparatus (10) comprises red-light emitting means (15) and blue-light emitting means (16), in particular diodes, for emitting red light and blue light, respectively, and directing the emitted light into a target zone (14) for irradiation of plant matter (13) when disposed in the zone. The diodes (15, 16) are operable to provide a substantially homogenous blend of the emitted red and blue light in the target zone for at least a major part of the period of emission and to emit the light at wavelengths of 625 to 660 nanometres for the red light and 440 to 470 nanometres for the blue light with intensities in the target zone of up to 500 microEinsteins for the red light and up to 400 microEinsteins for the... |
| Integrated production of phytochemical rich plant products or isolates from green vegetation | 20100040758 | 20100218 |
| Invention provides improvement in process of green crop fractionation to provide a route for production of novel phytochemical compositions or ingredients containing natural products contained in green plant material. Primary products of green crop fractionation produced in conventional process are fractionated further by using processes of oil extraction, aqueous acid extraction, aqueous alkali extraction, solvent extraction or are modified further in their form leading to products that are enriched in either oil soluble phytochemicals or water soluble phytochemicals. Most of these products can be used for human consumption directly or as an ingredient of a composition with a minimal further processing. Choice exists of using a process that totally avoids use of volatile organic solvents.
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| Extraction of phytochemicals by enzymatic hydrolysis | 20100021969 | 20100128 |
| A process for extracting phytochemicals from plants. The process generally comprises controllably slurrying a selected plant material in a volume, adding a selected enzyme the slurry while it is controllably agitated, then heating the controllably agitated slurry-enzyme mixture to a temperature from the range of 40° C. to 110° C., and then maintaining the slurry-enzyme mixture at that temperature for a selected period of time. The slurry is then separated into a solids fraction and a liquids fraction that contains extracted phytochemicals. The liquids fraction is controllably de-watered to produce a fluid extract concentrate. The liquids fraction may optionally be dried to produce a dried extract concentrate. Suitable enzymes for use with this process include α-amylases, β-amylases, endo-β-1,4-glucanases, cellobiohydrolases, cellulases, hemicellulases, β-glucosidases, β-xylosidases, xylanases, pullulases, esterases... |
| Processes for extracting phytochemicals from pomegranate solids and compositions and methods of use thereof | 20100009019 | 20100114 |
| Processes for producing an extract containing phytochemicals from pomegranates are disclosed. The processes generally comprise providing pomegranate solids, such as the pericarp, inner membrane and seeds; creating a mixture comprising the pomegranate solids in an aqueous solution; adding enzymes to the mixture in an amount sufficient to at least partially degrade the pomegranate solids; heating the mixture to a temperature that permits the maximum rate of catalysis of the enzyme; maintaining the temperature of the heated mixture for a time sufficient to allow at least partial degradation of the pomegranate solids; and removing residual insoluble solid materials from the mixture. Compositions containing the extract may be used as a food product, beverage, pharmaceutical preparations, nutritional supplements, vitamin supplements, food additives, and food supplements. The compositions may... |
| Compositions containing non-polar compounds | 20090317532 | 20091224 |
| Provided herein are compositions and methods for preparing foods and beverages that contain additives. Additives include nutraceuticals, pharmaceuticals, and supplements, such as essential fatty acids, including omega-3 fatty acids, omega-6 fatty acids, conjugated fatty acids, and other fatty acids; phytochemicals, including phytosterols; other oils; and coenzymes, including Coenzyme Q10, and other oil-based additives.
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| Pulsed electric field enhanced method of extraction | 20090314630 | 20091224 |
| The present invention relates to a process enhancing the extraction of phytochemicals from plant materials using pulsed electric field. The process is also used with a step of pressing, wherein the pressing and the pulse electric field treatment can be accomplished in a unique treatment chamber.
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| Nutritional compositions for promotion of bone growth and maintenance of bone health and methods regarding same | 20090304823 | 20091210 |
| Compositions and methods for maintenance of bone health or prevention, alleviation and/or treatment of bone disorders are presented. The present invention also provides the manufacture of a nutritional product, a supplement or a medicament for promoting bone growth or for the maintenance of bone health and methods regarding same. In an embodiment, the present invention provides a composition comprising an active ingredient having an effective amount of a plant or plant extract containing at least one phytochemical having the ability to induce bone morphogenic protein expression.
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| Compositions containing non-polar compounds | 20090297665 | 20091203 |
| Provided herein are compositions and methods for preparing foods and beverages that contain additives, such as nutraceuticals, pharmaceuticals, and supplements, such as essential fatty acids, including omega-3 fatty acids, omega-6 fatty acids, conjugated fatty acids, and other fatty acids; phytochemicals, including phytosterols; other oils; and coenzymes, including Coenzyme Q10, and other oil-based additives.
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| Compositions containing non-polar compounds | 20090297491 | 20091203 |
| Provided herein are compositions and methods for preparing foods and beverages that contain additives, such as nutraceuticals, pharmaceuticals, and supplements, such as essential fatty acids, including omega-3 fatty acids, omega-6 fatty acids, conjugated fatty acids, and other fatty acids; phytochemicals, including phytosterols; other oils; and coenzymes, including Coenzyme Q10, and other oil-based additives.
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| Methods and compositions for controlled delivery of phytochemical agents | 20090274746 | 20091105 |
| The presently-disclosed subject matter provides compositions and methods for treating a cancer by providing a composition comprising a biocompatible polymeric matrix incorporating an effective amount of a phytochemical agent, a combination of phytochemical agents, or a phytochemical agent and a chemotherapeutic agent. Further, provided is a device for uterine cervical insertion for local delivery.
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| Methods and compositions for controlled delivery of phytochemical agents | 20090274746 | 20091105 |
| The presently-disclosed subject matter provides compositions and methods for treating a cancer by providing a composition comprising a biocompatible polymeric matrix incorporating an effective amount of a phytochemical agent, a combination of phytochemical agents, or a phytochemical agent and a chemotherapeutic agent. Further, provided is a device for uterine cervical insertion for local delivery.
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| Nutraceutical coatings fo fruits and vegetables | 20090142453 | 20090604 |
| A preharvest coating for fruits, vegetables and other plants includes a primary ingredient for protecting the fruit, vegetable or plant from physical harm or damage during growing and harvesting and/or for enhancing the appearance of the fruit, vegetable or plant. In addition, the coating includes a nutraceutical component that may provide health beneficial effects to human consumers of the fruit, vegetable or plant. Such nutraceutical components can include phytonutrients such as flavonoids, stilbenes or other phytochemicals. Preferably, the nutraceutical component is included in an otherwise conventional coating and is applied by means of preharvest thermofogging of the fruit, vegetable or plant.
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| Agave syrup extract having anticancer activity | 20090124685 | 20090514 |
| The present invention comprises an agave syrup stored for at least eight weeks, having phytochemicals preferably selected from the group comprising flavonoids, polycosanols and sapogenins, which provide anticancerigen and antioxidant properties to the agave syrup. It is also described an extract of said agave syrup and a related method for its extraction and application for inhibiting the growth of cancer cells.
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| Method for growing forskohlin containing coleus in a temperate climate | 20090126048 | 20090514 |
| The present invention is a method of growing and harvesting forskohlin-containing cultivars of the Coleus plant in North America and other geographic areas that results in increased yield of the phytochemical forskohlin per plant, as well as increasing rhizome and root biomass.
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| Immunomodulatory alkaloids | 20090117083 | 20090507 |
| Immunotherapy comprises administration of an alkaloid at a dose sufficient to induce IL-2 production in dendritic cells in a patient. The alkaloid induces the production of IL-2 in dendritic cells. The alkaloids need not be naturally occurring, and may be synthetic analogues or derivatives of naturally occurring counterparts. Such analogues or derivatives are preferably pharmaceutically acceptable analogues, salts, isomers or derivatives as herein defined. However, preferred alkaloids are phytochemicals. Such phytochemicals may be isolated from natural sources or synthesised in vitro. Particularly preferred are alkaloids is selected from piperidine alkaloids; pyrrolin alkaloids; pyrrolidine alkaloids; pyrolizidine alkaloids: indolizidine alkaloids and nortropane alkaloids.
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| Process for the recovery of a phytolipid composition | 20090092686 | 20090409 |
| Disclosed is a process for the recovery of a phytolipid composition from a vegetable oil by-product. The phytolipid composition produced comprises squalene, phytosterols, mixed tocopherols and tocotrieneols, and vegetable wax and is useful as an emollient. The phytochemical composition may be applied directly to the skin to provide emolliency. Alternatively, the phytolipid composition may be formulated in various aqueous or anhydrous cosmetic compositions such as creams, lotions, gels, ointments, lip balms, sticks, or pencils for treatment of the skin and lips. The phytolipid composition also may be incorporated into foods, beverages, and nutraceuticals to provide health benefits.
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| Stabilized, biocompatible gold nanoparticles and enviro-friendly method for making same | 20090074674 | 20090319 |
| The invention provides stabilized, biocompatible gold nanoparticles that are stabilized with material from polyphenols- or flavanoids-rich plant material or reactive phytochemical components of the plant material. The gold nanoparticles of the invention can be fabricated with an environmentally friendly method for making biocompatible stabilized gold nanoparticles. In methods of the invention, an aqueous solution containing gold salts is mixed with polyphenols- or flavanoids-rich plant material. In preferred embodiment methods of making, an aqueous solution containing gold salts is provided. The aqueous solution is mixed with black tea, turmeric, curcumin or cinnamon or a similar naturally occurring polyphenols- or flavanoids-rich plant material. The gold salts react to form biocompatible gold nanoparticles that are stabilized with a coating of the polyphenols- or flavanoids-rich plant material. The black tea,... |
| Treatment of vegetation liquors derived from oil-bearing fruit | 20090053333 | 20090226 |
| The present invention relates to processes for the treatment of liquors derived from oil-bearing fruit, for example from oil palm fruit, and to products therefrom. Typically a process involves removal of undissolved solids, oleaginous parts, colloids and higher weight molecules from the vegetation liquor to give an aqueous fraction containing phytochemicals, for example, flavonoids, phenolic acids and hydroxy acids. Subsequently, pH adjustment and solvent extraction upon said aqueous fraction realise an extract rich in hydroxy acids or phenolic acids or flavonoids or any combination thereof. Applications of the substances subject of this invention are to be found in drinks, edible products, tonics, health supplements, antioxidant additives, cosmetics, soaps, shampoos, detergents, drugs or medicinal products.
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| Composition and methods for treating and preventing age-related macular degeneration | 20090035369 | 20090205 |
| The present invention relates to methods and compositions effective in preventing, attenuating, inhibiting the progression of, and treating eye diseases, e.g., age-related macular degeneration (AMD). The compositions comprise, as an active ingredient, an effective amount of 3,3′-diindolylmethane (DIM) and/or its precursor indole-3-carbinol (I3C). The compositions can further comprise additional agents such as carotenoids and other phytochemicals, which produce a synergistic effect in preventing, attenuating, inhibiting the progression of, and treating AMD and other eye diseases such as glaucoma, cataracts and diabetic retinopathy (DR). The compositions are particularly effective in treating and preventing wet AMD, and in preventing or inhibiting the progression of dry AMD (non-neovascular) to wet AMD (neovascular).
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| Composition comprising five kinds of processed fruit or vegetables | 20080260924 | 20081023 |
| The present invention discloses a nutritional composition, comprising at least five kinds of processed fruit/vegetables: green processed fruit/vegetables, yellow/orange processed fruit/vegetables, white processed fruit/vegetables, red processed fruit/vegetables, and blue/purple processed fruit/vegetables. Moreover, the composition may further comprise at least one kind of artificially-added phytochemical, which is selected from the group consisting of flavonoids, carotenoids, phenolic acids, organosulfur compounds, other phytochemicals, and mixtures thereof.
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| Dietary supplement and related method | 20080226744 | 20080918 |
| A composition including a unique combination of fruits, vegetables, herbs, and optionally vitamins, minerals and specialty ingredients. The composition can include a fruit ingredient, a vegetable ingredient and an herbal ingredient, wherein the fruit ingredient is at least one of pomegranate and citrus bioflavonoids, wherein the vegetable ingredient, is at least one of asparagus, lutein, lycopene and watercress, and wherein the herbal ingredient is at least one of basil, oregano and rosemary. The composition can be administered to subjects to correct a dietary deficiency of phytochemicals and other nutrients, improve plasma concentrations of antioxidant nutrients, and increase the activity of genetic mechanisms for DNA repair and stability.
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| Biosynchronous transdermal drug delivery for longevity, anti-aging, fatigue management, obesity, weight loss, weight management, delivery of nutraceuticals, and the treatment of hyperglycemia, alzheimer's disease, sleep disorders, parkinson's disease, aid | 20080220092 | 20080911 |
| Systems and methods for longevity, anti-aging, fatigue management, obesity, weight loss, weight management, delivery of nutraceuticals, and treating hyperglycemia, Alzheimer's disease, sleep disorders, Parkinson's disease, Attention Deficit Disorder and nicotine addiction involve synchronizing and tailoring the administration of nutraceuticals, medications and other substances (for example, stimulants) in accordance with the body's natural circadian rhythms, meal times and other factors. Improved control of blood glucose levels, extended alertness, and weight control, and counteracting of disease symptoms when they are at their worst are possible. An automated, pre-programmable transdermal administration system is used to provide pulsed doses of medications, pharmaceuticals, hormones, neuropeptides, anorexigens, pro-drugs, stimulants, plant extracts, botanicals, nutraceuticals, cosmeceuticals, phytochemicals, phytonutrients, enzymes, antioxidants, essential oils, fatty acids, minerals, vitamins, amino acids, coenzymes, or other physiological active ingredient... |
| Folate based migraine treatment | 20080206360 | 20080828 |
| Formulations for the prevention and treatment of headaches, particularly migraine headaches, comprise folate in combination with one or more of riboflavin, feverfew, or an extract of feverfew, magnesium in the form of acid salts, magnesium oxide, complexes or chelates and/or other nutritional supplements such as vitamin B6, B12, betaine, and plant derived phytochemicals or synthesized versions thereof.
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| Antiestrogenic glyceollins suppress human breast and ovarian carcinoma proliferation and tumorigenesis | 20080200537 | 20080821 |
| The flavonoid family of phytochemicals, particularly those derived from soy, has received attention regarding their hormonal activity and their effects on human health and disease. The types and amounts of these compounds in soy and other plants are controlled by both constitutive expression and stress-induced biosynthesis. The health benefits of soy may therefore be dependent upon the amounts of the various hormonally active phytochemicals present. We have identified increased biosynthesis of the isoflavonoid phytoalexin compounds, Glyceollins I, II and III, in soy plants grown under stressed conditions (elicited soy), which exhibit marked anti-estrogenic effects on ER function. Here we demonstrate that specific glyceollins, isolated from elicited soy, displayed anti-estrogenic activity, suppressing basal and estrogen stimulated colony formation of ER-positive estrogen dependent breast cancer cells and inhibiting... |
| Method for measuring and comparing the activity of biologically active compounds | 20080194417 | 20080814 |
| Biologically active compounds (e.g. from the groups of pharmaceutical drugs, cofactors, hormones, vitamins or phytochemicals) often consist of two or more stereoisomers (enantiomers or diastereoisomers) which may differ in their pharmacodynamic/kinetic, toxicological and biological properties. These differences are so far difficult to detect. A well known example for a biologically active compound and its counterpart is vitamin E which is predominantly administered as two different ‘forms’, one derived from natural sources (mainly soybeans), and one from production by chemical total-synthesis. While vitamin E from natural sources occurs as a single stereoisomer (RRR-α-tocopherol), so-called synthetic vitamin E (all-rac-α-tocopherol) is an equimolar mixture of eight stereoisomers. The present invention is directed to a method for calculating the biological activity of a biologically active compound (e.g. RRR-α-tocopherol) and a... |
| Polymer coatings containing phytochemical agents and methods for making and using same | 20080175812 | 20080724 |
| This invention relates to compositions comprising a polymer base incorporating antifouling compositions suitable for use in aquaculture, marine and architectural systems as paints, structures or coatings. In particular, the present invention relates to a polymer based coating incorporating a biocidal antifouling composition suitable for use with aquaculture equipment. The present invention provides polyethylene compositions and latex compounds which may comprise at least one environmentally benign phytochemicals suitable for use in preventing the colonization of a treated surface by a variety of biological species. The compositions of the invention may further comprise control release agents such as, for example, micro-encapsulation of the phytochemicals to maintain sustained and prolonged release of the biocidal agents at the treated surface.
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| Diindolylmethane for the treatment of hpv infection | 20080145418 | 20080619 |
| New methods and compositions are disclosed that comprise the phytochemical Diindolylmethane, alone or in combination with immune potentiating steroids. These methods and compositions are utilized to treat subjects suffering from common cutaneous warts (verrucae) and Human Papilloma Virus (HPV) related conditions of the oropharynx, larynx, genitalia, and uterine cervix.
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| Process for the recovery of a phytolipid composition | 20080138450 | 20080612 |
| Disclosed is a process for the recovery of a phytolipid composition from a vegetable oil by-product. The phytolipid composition produced comprises squalene, phytosterols, mixed tocopherols and tocotrieneols, and vegetable wax and is useful as an emollient. The phytochemical composition may be applied directly to the skin to provide emolliency. Alternatively, the phytolipid composition may be formulated in various aqueous or anhydrous cosmetic compositions such as creams, lotions, gels, ointments, lip balms, sticks, or pencils for treatment of the skin and lips. The phytolipid composition also may be incorporated into foods, beverages, and nutraceuticals to provide health benefits.
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| Topical and intravaginal microbicidal ad antiparsitic compositions comprising quassinoids or quassinoid-containing plant exrtracts | 20080089958 | 20080417 |
| Pharmaceutical or dermo-cosmetic compositions for topical and intravaginal application for treatment of human and veterinary affections caused by anaerobic organisms or parasites are provided comprising quassinoids or plant extracts containing these phytochemicals, in effective amounts. Such compositions can be administered topically or intravaginally to patients in need thereof in various pharmaceutical dosage forms.
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| Compositions and methods for attracting noctuid moths | 20080044375 | 20080221 |
| The invention provides compositions for attracting stink bugs, which include at least one pheromone and at least one synergist The synergist is a naturally-occurring phytochemical compound. The pheromone is preferably methyl (2E,4Z)-decadienoate, ethyl (2E,4Z)-decadienoate, methyl (2Z,4E)-decadienoate, or methyl (2E,4E)-decadienoate and the synergist is preferably geraniol. The invention also provides traps containing the composition for attracting stink bugs, and methods for attracting, capturing, killing or sterilizing stink bugs using the composition.
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| Compositions and methods for attracting noctuid moths | 20080044446 | 20080221 |
| The invention provides compositions for attracting noctuid moths, which include at least one pheromone and at least one synergist. The synergist is a naturally-occurring phytochemical compound. The synergist is preferably β-caryophyllene, iso-caryophyllene, α-humulene, or combinations thereof. The invention also provides traps containing the composition for attracting noctuid moths, and methods for attracting, capturing, killing or sterilizing noctuid moths using the composition.
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| Natural sweetener | 20080045464 | 20080221 |
| The invention relates to extracts, in particular non-nutrient phytochemicals, form sugar cane or sugar beet waste products, such as molasses, sugar mud and bagasse, which have Glycemic Index (GI) lowering properties and their use as sweeteners and in foods containing sugar.
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| Food supplement | 20080014305 | 20080117 |
| Food supplements are disclosed for supplementing the minerals, trace elements and phytochemicals in food. One form of the supplement comprises folic acid, lycopene and an extract of Aspalathus linearis (common name Red Bush) or Cyclopia intermedia (common name Honeybush) or a mixture of extracts of Aspalathus linearis and Cyclopia intermedia. Another form comprises lycopene and folic acid. They lycopene and folic acid are dispersed in canola oil.
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| Dissolution of arterial cholesterol plaques by phytochemical emulsifiers | 20070249543 | 20071025 |
| As a result of this phyto-pharmacological direct action upon the atherosclerotic plaque by the phytocompound resulting in the dissolution of the cholesterol aggregates of the plaque, the plaque is no longer vulnerable to rupture and arterial flow is restituted to physiological values present prior to plaque formation. This effect on the lipid core of the plaque by the saponin is expected to reduce and/or eliminate altogether preexisting atherosclerotic lesions and significantly reduce chances of acute and chronic ischemic events.
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| Methods of making and using nutritional compositions | 20070184164 | 20070809 |
| The invention provides premixes in solid particulate form comprising fruit seed or fruit seed fractions for the preparation of food products supplemented with linolenic acid, soluble or insoluble dietary fiber, antioxidants, phytochemicals or any combination thereof, and methods of preparing and using the premixes and supplemented food products of the invention.
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| Methods for altering the level of phytochemicals in plant cells by applying wave lengths of light from 400 nm to 700 nm and apparatus therefore | 20070151149 | 20070705 |
| A method of altering the level of at least one phytochemical in a plant cell comprising chlorophyll or in plant tissue comprising chlorophyll by irradiating the said plant cell or plant tissue with light of at least one wavelength selected from the range of wavelengths of from 400 nm to 700 nm, use of wavelengths of light selected from said range for altering the level of phytochemicals in plant tissue, harvested plant parts comprising altered levels of phytochemicals, and apparatuses for generating plant tissue having altered levels of phytochemicals therein.
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| Skin care compositions | 20070141012 | 20070621 |
| The invention provides materials and methods for making skin care compositions that contain dried or fresh fruit particles, and also can contain suspending agents, surfactants, emollients, emulsifiers, and/or cationic polymers. The basic fruit components typically are from the pulp and peel of the fruit, which can be specially processed to retain the colors, phytochemicals and nutritive ingredients. The compositions provided herein can contain particles made from whole fruits (minus seeds, leaves, and stems) that have been subjected to drying techniques (e.g., air-drum drying or freeze drying) and then processed into small particles.
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| Corporeal delivery of carotenoids | 20070122363 | 20070531 |
| A method for delivery of a phytochemical supplement to a corporeal body. The method of delivery comprises providing a phytochemical supplement in an orally acceptable composition and applying the orally acceptable composition including the phytochemical supplement in contact with a feature of the oral cavity of a corporeal body. An oral care composition comprising a phytochemical supplement for one or more of ingestion or trans-mucosal absorption and a method for making the same are also disclosed.
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| Methods of making compositions comprising a uv-absorbing chromophore | 20070077636 | 20070405 |
| wherein at least two of R1, R2, and R3 are non-fatty acid carboxylates, and the other of R1, R2, and R3 are each either a C2-C24 fatty acid moiety, OH, or a non-fatty acid carboxylate, wherein the first and second non-fatty acid carboxylates, when present, are the same or different, comprising (a) partially deacylating a triacylglycerol so as to provide a mono- or diacylglycerol, (b) reacting in a reaction mixture an acyl ester of the phytochemical with said mono- or diacylglycerol in the presence of a esterase catalyst under conditions that permit transesterification of said ester with said mono- or diacylglycerol, and (c) recovering said compound from said reaction mixture.
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| Method of making antitussive medicine and relieving cough | 20070060564 | 20070315 |
| Method for relieving cough using an effective antitussive chemical compound belonging to stemoamide or tuberostemospironine and method for manufacturing pharmaceutical compositions for treating or relieving cough in human and animal subjects which including a stemoamide or tuberostemospironine compound. In addition, the antitussive property of the compounds provides a method for assessing the quality of herbs traditionally used in treating cough by analyzing the content of the effective chemical ingredient, i.e., compounds of stemoamide type and/or tuterostemospironine type. It further provides a method for identifying medicinal herbs which may be used for relieving cough by phytochemical determination of the existence of compounds that are of stemoamide or tuterostemospironine type.
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| Methods of extracting, concentrating and fractionating proteins and other chemical components | 20070054031 | 20070308 |
| Methods are disclosed herein to extract, concentrate and fractionate proteins and protein-associated complexes with other polymers from soybeans, peanuts, rape, canola, cottonseeds, peas, wheat and other plant materials, based on a principle of cryoprecipitation. The disclosed methods involve no or minimal uses of chemicals, and generate a minimal volume of waste streams. The resulting protein concentrates or isolates have excellent functionality, superior nutritional quality, attractive appearance and mild taste. Based on the sample principle of cryoprecipitation, methods also are also disclosed to extract and concentrate chemical components from living tissues, especially some nutraceutical or phytochemical components from plant materials.
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| Extraction of phytochemicals | 20070014912 | 20070118 |
| A processing system and methods for extracting phytochemicals from plant materials with subcritical water. The processing system includes a water supply interconnected with a high-pressure pump, diverter valve, a temperature-controllable extraction vessel, a cooler, a pressure-relief valve and a collection apparatus for collecting eluant fractions from the extraction vessel. The processing system controllably varies the temperature of subcritical water within the extraction vessel, and may optionally be configured to controllably vary the pH of subcritical water flowing into the extraction vessel. A plant material is placed into the extraction vessel after which a flow of subcritical water is provided through the extraction vessel for extraction of phytochemicals. The temperature of subcritical water is controllably varied during its flow through the extraction vessel water thereby producing a... |
| Processes for extracting phytochemicals from pomegranate solids and compositions and methods of use thereof | 20060269629 | 20061130 |
| Processes for producing an extract containing phytochemicals from pomegranates are disclosed. The processes generally comprise providing pomegranate solids, such as the pericarp, inner membrane and seeds; creating a mixture comprising the pomegranate solids in an aqueous solution; adding enzymes to the mixture in an amount sufficient to at least partially degrade the pomegranate solids; heating the mixture to a temperature that permits the maximum rate of catalysis of the enzyme; maintaining the temperature of the heated mixture for a time sufficient to allow at least partial degradation of the pomegranate solids; and removing residual insoluble solid materials from the mixture. Compositions containing the extract may be used as a food product, beverage, pharmaceutical preparations, nutritional supplements, vitamin supplements, food additives, and food supplements. The composition may... |
| Antiestrogenic glyceollins suppress human breast and ovarian carcinoma proliferation and tumorigenesis | 20060246162 | 20061102 |
| The flavonoid family of phytochemicals, particularly those derived from soy, has received attention regarding their hormonal activity and their effects on human health and disease. The types and amounts of these compounds in soy and other plants are controlled by both constitutive expression and stress-induced biosynthesis. The health benefits of soy may therefore be dependent upon the amounts of the various hormonally active phytochemicals present. We have identified increased biosynthesis of the isoflavonoid phytoalexin compounds, Glyceollins I, II and III, in soy plants grown under stressed conditions (elicited soy), which exhibit marked anti-estrogenic effects on ER function. Here we demonstrate that specific glyceollins, isolated from elicited soy, displayed anti-estrogenic activity, suppressing basal and estrogen stimulated colony formation of ER-positive estrogen dependent breast cancer cells and inhibiting... |
| Use of herbs as a delivery system for bioactive phytochemicals | 20060194698 | 20060831 |
| The subject invention provides methods for cotrolling weeds, plant pests, or plant pathogens comprising the application of a bioactive herbage (plant material) composition to soil as a soil amendment or as top dressing for potted plants. In certain embodiments, the method of controlling weeds, plant pests, or plant pathogens comprises the application of a bioactive herbage (plant material) composition to soil as a soil amendment or as top dressing for potted plants in amounts sufficient to control weeds, plant pests, or plant pathogens, wherein said bioactive herbage is obtained from: (a) Monarda spp.; (b) Chamaemelum spp.; (c) Matricaria spp.; (d) Chenopodium spp.; or (e) various combinations of thereof. Herbage can be dried or wet and other sources of bioactive herbage are also suitable for use in... |
| Process for producing sugars and acids-rich juice and phytochemical-rich juice | 20060177560 | 20060810 |
| A method is described for processing fruit or vegetables, e.g., cranberries, into two different juices. One of the two juices has a relatively high level of phytochemicals and a relatively low level of sugars and acids. The other of the two juices has a relatively low level of phytochemicals and a relatively high level of sugars and acids. The method of the invention entails providing three juice streams. The first juice stream is passed through an ultrafiltration apparatus or some other apparatus that is capable of preferentially separating the relatively lower molecular weight compounds, e.g., sugars and acids, from the relatively higher molecular weight compounds, e.g., phytochemicals. This process creates two juice fractions: a juice fraction that is relatively enriched in sugars and acids and a... |
| Protective barriers for micronutrients, phytochemicals, and nutraceuticals | 20060134132 | 20060622 |
| Compositions that act as a protective barrier for micronutrients, phytochemicals, and nutraceuticals such as may be found in food products, for example food additives. Also, a process for producing food additives using the compositions.
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| Breast health supplement and detoxification preparations | 20060134244 | 20060622 |
| Novel preparations of phytochemical ingredients that are serviceable as health supplements for the body, particularly tissues susceptible to cancer, including, e.g. prostate tissue and breast tissue and, including, e.g., female breast tissue; for example, all possible combinations and permutations of member from each of the following 6 groups: 1) plant indoles, including sources of plant indoles (e.g. diindolemethane); 2) plant flavonoids, polyphenols, stilbenes and related substances, including sources of plant flavonoids, polyphenols, stilbenes, and related substances (e.g. resveratrol and piceatannol); 3) D-glucaric acid and derivatives thereof (e.g. calcium D-glucarate and 1,4-GL) and sources thereof; 4) medium chain triglycerides and sources thereof; 5) phospholipids and sources thereof (e.g. lecithin), and 6) vitamins (especially vitamin B9 molecules).
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