Photodynamic Therapy

Photodynamic Therapy-related patent applications - as published by the U.S. Patent and Trademark Office (USPTO).

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Multi-modal bioprobe for bladder cancer imaging and photodynamic therapy
Hong Kong Baptist University
April 20, 2017 - N°20170107238

The present invention relates to a new generation of pdt agents based on porphyrin-lanthanide complexes with specific functional groups which can specifically localize on particular tumors, and their pdt processes can be monitored via nir emission from erbium. In particular, the present invention provides a multi-modal lanthanide-porphyrin pdt agent (er—r3) that are capable of killing the bladder tumor ...
Adjustable illuminator for photodynamic therapy and diagnosis
Dusa Pharmaceuticals, Inc.
April 20, 2017 - N°20170106205

An adjustable illuminator for photodynamically diagnosing or treating a surface includes a plurality of first panels and at least one second panel. The plurality of first panels have wider widths and the at least one second panel has a narrower width. The narrower width is less than the wider widths. The illuminator further includes a plurality of light sources, each ...
Diagnostic device, therapeutic device, and uses thereof
Cerca Solutions, Llc
April 13, 2017 - N°20170100073

Apparatus, method, computing devices, and computer programs related to photodiagnosis and photodynamic therapy, methods of use thereof, and a method for detecting abnormal tissue, are provided,
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Focal photodynamic therapy methods
Steba Maor Sa
March 30, 2017 - N°20170087375

Improved methods of treating prostate cancer by vascular-targeted photodynamic therapy, and improved methods of planning treatment, are presented using a light density index to plan and guide effective treatment.
Photodynamic therapy, formulation usable for this purpose, and method for the production and use thereof
Sanochemia Pharmazeutika Ag
March 30, 2017 - N°20170087249

A treatment of cancer, such as, for example, bladder cancer, uses a formulation that contains sodium hypericinate that is bonded to polyvinylpyrrolidone or complexed with polyvinylpyrrolidone.
Irradiation device
Photocure Asa
March 16, 2017 - N°20170072217

An irradiation device for insertion into an orifice of the body for providing photodynamic therapy or diagnosis comprises: a housing 1, 21, 31, 51, 61, 71 adapted to be fully inserted and secured in the orifice, the housing 1, 21, 31, 51, 61, 71 enclosing an led lamp system 5, 25, 35, 45, 54, 62, 72 and a power source 41, 68, 78, for powering the led lamp system 5, 25, 35, 45, 54, 62, 72, wherein the device is independently operational while located within the orifice.
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Photodynamic therapy using in situ nonlinear photon upconversion of nir light by biological medium
The Research Foundation For The State University Of New York
February 23, 2017 - N°20170050045

Photodynamic therapy methods using near infrared light and visible-light-absorbing photosensitizers and methods of generating visible light in an individual. The methods use upconverted incident near infrared light, for example, to excite the photosensitizer or facilitate drug delivery. The methods can be carried out on humans and non-human animals.
5-aminolevulinic acid conjugated quantum dot nanoparticle
Nanoco Technologies Ltd.
February 23, 2017 - N°20170049891

A 5-aminolevulinic acid conjugated quantum dot nanoparticle is useful for treating cancer by administering the 5-aminolevulinic acid conjugated quantum dot nanoparticle in photodynamic therapy as a precursor of both a fluorescence label and a photosensitizer.
Methods and systems for detecting sub-tissue anomalies
The Board Of Regents Of The University Of Texas System
February 23, 2017 - N°20170049417

A diagnostic imaging device includes a probe that uses both an ultrasound transducer and frequency-domain diffuse optical imaging (fd-doi) to assist with locating and diagnosing sub-tissue anomalies. According to one aspect, the diagnostic imaging device relates to a clip-on cap that can be utilized with existing ultrasound transducers. The diagnostic imaging device described herein can be utilized for image-guided needle ...
Apparatus and method for multiwavelength photodynamic therapy
Theralase Technologies, Inc.
February 16, 2017 - N°20170043179

A method for treating a condition in a tissue, includes the steps: (1) providing a ps within the tissue; (2) irradiating the tissue containing the ps with a first light of a first wavelength; and (3) irradiating the tissue containing the ps with a second light of a second wavelength so as to treat the condition in the tissue, wherein: (a) the ps ...
Methods for cross-linking corneal collagen with verteporfin for the treatment of disorders of the eye
Massachusetts Eye And Ear Infirmary
February 16, 2017 - N°20170043015

Described are compositions and methods of using verteporfin-based photodynamic therapy (pdt) to increase the biomechanical strength of the cornea. More particularly, described herein are compositions and methods for cross-linking collagen in corneal tissue which are useful in the treatment of corneal ectatic disorders.
Metal-glycoprotein complexes and photodynamic therapy of immune privileged sites with same
Theralase Technologies, Inc.
February 16, 2017 - N°20170042976

Compositions of the invention include glycoproteins, such as transferrin, and metal-based coordination complexes, which are preferably chemotherapeutic compounds and more preferably tunable photodynamic compounds. The compositions are useful as in vivo diagnostic agents, and as therapeutic agents for treating or preventing diseases including those that involve hyperproliferating cells in their etiology, such as cancer. Compositions of the invention are further ...
Lung targeting dual drug delivery system
Rutgers, The State University Of New Jersey
February 16, 2017 - N°20170042818

The american cancer society estimated that in 2009, 1,479,350 new cancer cases would be diagnosed in the united states of which 219,440 would be lung and bronchus related. The standard treatments for nsclc include surgery, chemotherapy, radiation, laser and photodynamic therapy, all with various success rates depending on the stage of the cancer. National cancer institute assesses, however, that results of standard treatment ...
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Uniform core-shell tio2 coated upconversion nanoparticles and use thereof
National University Of Singapore
January 05, 2017 - N°20170000887

An upconversion nanoparticle (ucn) coated with a layer of semiconductor material is disclosed. The ucn core acts as a nanotransducer to convert near infrared (nir) to visible and/or ultraviolet (uv) light while the semiconductor shell serves as a photocatalyst. Upon excitation by nir light, the ucn upconverts nir light to uv and/or visible light of different wavelengths. Spectral ...
Dual panel photodynamic therapy lamp
Photocure Asa
December 22, 2016 - N°20160367832

A photodynamic therapy lamp includes two lamp modules comprising an array of leds. Each of the lamp modules is movable between a first position in which an angle between the lamp modules is from 157 degrees to 180 degrees, and a second position in which the angle between the lamp modules is from 50 degrees to 70 degrees.
Combination artemisinin and chemiluminescent photodynamic therapy and uses therefor
Washington University
December 22, 2016 - N°20160367674

Photodynamic therapy-based methods of treating diseases such as cancer and malaria are disclosed. These methods include administering 5-aminolevulinic acid (ala), luminol and artemisinin (art). Art and ala administered in combination with luminol can kill malaria parasites without host toxicity. In some aspects, the methods further include administration of a luminol enhancer such as 4-iodophenol. The disclosed methods can also be ...
Composition for prevention or treatment of treatment-resistant cancer
Washington University
December 15, 2016 - N°20160361418

[solution] a preventive or therapeutic composition for a therapy-resistant cancer having therapy-resistant cancer cells, which is for use in photodynamic therapy, wherein the composition comprises alas.
Pulse photodynamic treatment of skin conditions
Galderma Research & Development
December 01, 2016 - N°20160346392

A pulse photodynamic therapy (or pulse pdt) treatment of skin complaints is described herein. The skin complaint being treated can be actinic keratosis (ak) or a basal cell carcinoma (bcc).
Nanoscale carriers for the delivery or co-delivery of chemotherapeutics, nucleic acids and photosensitizers
The University Of North Carolina At Chapel Hill
December 01, 2016 - N°20160346204

Nanoscale coordination polymer nanoparticles for the co-delivery of multiple therapeutic agents are described. The multiple therapeutic agents can include a combination of different chemotherapeutic agents, a combination of one or more chemotherapeutic agents and one or more nucleic acids, such as small interfering rna (sirna) or microrna, a combination of one or more chemotherapeutic agents and a photosensitizer (i. E., ...
Pulse photodynamic treatment of acne
Galderma Research & Development
November 24, 2016 - N°20160339222

A pulse photodynamic therapy (or pulse pdt) treatment of acne is described herein.
Device and method for use of photodynamic therapy
Galderma Research & Development
November 10, 2016 - N°20160325110

An apparatus including a light source provides for intracranial treatment of a tissue region of a brain of a patient. The intracranial treatment apparatus comprises an outer shaft having a proximal end and a distal end for positioning within the tissue region of the brain. The outer shaft defines a lumen extending between the proximal end and the distal end ...