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Photodynamic Therapy

Photodynamic Therapy-related patent applications - as published by the U.S. Patent and Trademark Office (USPTO).


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Assembly for photodynamic therapy
October 05, 2017 - N°20170281965

An assembly for photomedicine therapy comprising: (a) at least partially transparent body having an internal cavity; the internal cavity provided with input and output pipes configured for circulating a cooling agent via said internal cavity; and (b) at least one electrically energizable light source disposed within said internal cavity such that radiation from said at least one light source propagates ...
Photodynamic therapy composition
Case Western Reserve Univerity
October 05, 2017 - N°20170281789

A phthalocyanine compound or targeted conjugate thereof having the formula (i).
Multimodal ultrasound and photoacoustic contrast agent based on polymeric microparticles
Fujifilm Sonosite B.v.
September 07, 2017 - N°20170252467

The invention provides a multimodal ultrasound and photoacoustic contrast agent based on polymeric microparticles having a gas core and carrying at least one photoacoustic agent in its shell that stabilizes the gas core, for use in ultrasound and photoacoustic imaging. Such multimodal ultrasound and photoacoustic contrast agent is also suitable as a carrier of drugs and for use in photodynamic ...
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Nanoparticles for photodynamic therapy, x-ray induced photodynamic therapy, radiotherapy, chemotherapy, immunotherapy, and any combination thereof
The University Of Chicago
August 17, 2017 - N°20170231903

Metal-organic frameworks (mofs) comprising photosensitizers are described. The mofs can also include moieties capable of absorbing x-rays and/or scintillation. Optionally, the photo sensitizer or a derivative thereof can form a bridging ligand of the mof. Further optionally, the mof can comprise inorganic nanoparticles in the cavities or channels of the mof or can be used in combination with an ...
Adjustable illuminators and methods for photodynamic therapy and diagnosis
Dusa Pharmaceuticals, Inc.
August 03, 2017 - N°20170216616

An illuminator for photodynamically diagnosing or treating a surface includes a plurality of panels. The illuminator further includes a plurality of light sources, each mounted to one of the plurality of panels. The plurality of light sources are configured to irradiate the surface with substantially uniform intensity visible light. The illuminator also includes a heat source configured to emit heat ...
Induced photodynamic therapy using nanoparticle scintillators as transducers
University Of Georgia Research Foundation, Inc.
July 27, 2017 - N°20170209575

Photodynamic therapy systems comprising a nanoparticle that emits electromagnetic radiation having a first wavelength when irradiated with electromagnetic radiation, a photosensitizer which absorbs electromagnetic radiation of said first wavelength and a biocompatible mesoporous material are disclosed herein. In some examples, the photodynamic therapy system comprises a core comprising the nanoparticle, a first shell comprising the biocompatible mesoporous material, and a ...
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Photodynamic therapy photosensitizers
The Royal Institution For The Advancement Of Learning/mcgill University
July 13, 2017 - N°20170197993

A compound of formula (i) useful as a photosensitizer in photodynamic therapy is provided. There is also provided a photosensitizing composition for use in photodynamic therapy comprising this compound. Finally, there are provided a method of killing cells under oxidative stress conditions and a method for the selective delivery of singlet oxygen (1o2) to cells having an increased reactive oxygen ...
Device and method for use of photodynamic therapy
The Royal Institution For The Advancement Of Learning/mcgill University
June 22, 2017 - N°20170173351

An apparatus including a light source provides for intracranial treatment of a tissue region of a brain of a patient. The intracranial treatment apparatus comprises an outer shaft having a proximal end and a distal end for positioning within the tissue region of the brain. The outer shaft defines a lumen extending between the proximal end and the distal end ...
Polymers and oligomers with aggregation-induced emission characteristics for imaging and image-guided therapy
The Hong Kong University Of Science And Technology
June 15, 2017 - N°20170168041

A fluorophore or conjugated polymer with aggregation-induced emission characteristics useful for drug tracking and delivery, identification and labeling of biological subjects, such as cells or parts of a cell, as well as for imaging, and image-guided photodynamic therapy are described herein.
Synthesis and composition of photodynamic therapeutic agents for the targeted treatment of cancer
The Hong Kong University Of Science And Technology
May 25, 2017 - N°20170145035

The present invention describes new compounds that are useful for image-guided surgery and photodynamic therapy. In particular the compounds may be targeted to the nucleus or the mitochondria after compounds were delivered to diseased tissues such as cancer using a ligand that target receptor that express on the diseased tissue and followed by receptor mediated endocytosis and provide effective activity ...
Water soluble anionic bacteriochlorophyll derivatives and their uses
The Hong Kong University Of Science And Technology
May 25, 2017 - N°20170143988

The invention provides anionic water-soluble tetracyclic and pentacyclic bacteriochlorophyll derivatives (bchls) containing at least one, preferably two or three, negatively charged groups and/or acidic groups that are converted to negatively charged groups at the physiological ph, preferably bchls having a group coo<−>, cos<−>, so3<−>, ...
Multi-modal bioprobe for bladder cancer imaging and photodynamic therapy
Hong Kong Baptist University
April 20, 2017 - N°20170107238

The present invention relates to a new generation of pdt agents based on porphyrin-lanthanide complexes with specific functional groups which can specifically localize on particular tumors, and their pdt processes can be monitored via nir emission from erbium. In particular, the present invention provides a multi-modal lanthanide-porphyrin pdt agent (er—r3) that are capable of killing the bladder tumor ...
Adjustable illuminator for photodynamic therapy and diagnosis
Dusa Pharmaceuticals, Inc.
April 20, 2017 - N°20170106205

An adjustable illuminator for photodynamically diagnosing or treating a surface includes a plurality of first panels and at least one second panel. The plurality of first panels have wider widths and the at least one second panel has a narrower width. The narrower width is less than the wider widths. The illuminator further includes a plurality of light sources, each ...
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Novel polygonum cuspidatum extracts and their use as photodynamic inactivating agents
Photodynamic Inc.
April 06, 2017 - N°20170095521

The present invention describes extracts of polygonum cuspidatum and related compositions that are capable of photodynamic inactivation (pdi) of microorganisms such as bacteria, viruses, fungi, and protozoa, and capable of killing or inactivating cancer cells. The present invention further describes methods of using said polygonum cuspidatum extracts and photodynamic inactivation (pdi) as a therapy for the treatment of microbial infection ...
Focal photodynamic therapy methods
Steba Maor Sa
March 30, 2017 - N°20170087375

Improved methods of treating prostate cancer by vascular-targeted photodynamic therapy, and improved methods of planning treatment, are presented using a light density index to plan and guide effective treatment.
Photodynamic therapy, formulation usable for this purpose, and method for the production and use thereof
Sanochemia Pharmazeutika Ag
March 30, 2017 - N°20170087249

A treatment of cancer, such as, for example, bladder cancer, uses a formulation that contains sodium hypericinate that is bonded to polyvinylpyrrolidone or complexed with polyvinylpyrrolidone.
Irradiation device
Photocure Asa
March 16, 2017 - N°20170072217

An irradiation device for insertion into an orifice of the body for providing photodynamic therapy or diagnosis comprises: a housing 1, 21, 31, 51, 61, 71 adapted to be fully inserted and secured in the orifice, the housing 1, 21, 31, 51, 61, 71 enclosing an led lamp system 5, 25, 35, 45, 54, 62, 72 and a power source 41, 68, 78, for powering the led lamp system 5, 25, 35, 45, 54, 62, 72, wherein the device is independently operational while located within the orifice.
Ultraslow light and nondegenerate phase conjugation-based real-time, non-invasive, in-vivo deep-tissue optical imaging apparatus, photodynamic therapy ...
Gwangju Institute Of Science And Technology
March 02, 2017 - N°20170055838

The present invention provides a method which can significantly increase the signal-to-noise ratio of an ultrasound-modulated optical signal by overcoming the shallow depth problem of in vivo optical imaging in existing optical imaging by use of a quantum optical phenomenon based on ultraslow light and nondegenerate phase conjugation and which can be applied directly not only to medical optical imaging, ...
Photodynamic therapy using in situ nonlinear photon upconversion of nir light by biological medium
The Research Foundation For The State University Of New York
February 23, 2017 - N°20170050045

Photodynamic therapy methods using near infrared light and visible-light-absorbing photosensitizers and methods of generating visible light in an individual. The methods use upconverted incident near infrared light, for example, to excite the photosensitizer or facilitate drug delivery. The methods can be carried out on humans and non-human animals.
5-aminolevulinic acid conjugated quantum dot nanoparticle
Nanoco Technologies Ltd.
February 23, 2017 - N°20170049891

A 5-aminolevulinic acid conjugated quantum dot nanoparticle is useful for treating cancer by administering the 5-aminolevulinic acid conjugated quantum dot nanoparticle in photodynamic therapy as a precursor of both a fluorescence label and a photosensitizer.
Methods and systems for detecting sub-tissue anomalies
The Board Of Regents Of The University Of Texas System
February 23, 2017 - N°20170049417

A diagnostic imaging device includes a probe that uses both an ultrasound transducer and frequency-domain diffuse optical imaging (fd-doi) to assist with locating and diagnosing sub-tissue anomalies. According to one aspect, the diagnostic imaging device relates to a clip-on cap that can be utilized with existing ultrasound transducers. The diagnostic imaging device described herein can be utilized for image-guided needle ...
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