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Photodynamic Therapy patents



      
           
This page is updated frequently with new Photodynamic Therapy-related patent applications. Subscribe to the Photodynamic Therapy RSS feed to automatically get the update: related Photodynamic RSS feeds. RSS updates for this page: Photodynamic Therapy RSS RSS


Date/App# patent app List of recent Photodynamic Therapy-related patents
08/28/14
20140243534
 Halogenated compounds for photodynamic therapy patent thumbnailnew patent Halogenated compounds for photodynamic therapy
Halo-organic heterocyclic compounds are described, in which at least two halogen atoms are bound to a nitrogen-containing heterocyclic terminal moiety of the compound, with at least one of such halogen atoms being iodine or bromine. Also described are polymethine dyes based on these heterocyclic compounds, and dendrimeric compounds and conjugates of such polymethine dyes.
08/07/14
20140220143
 Immune-stimulating photoactive hybrid nanoparticles patent thumbnailImmune-stimulating photoactive hybrid nanoparticles
Provides is a therapeutic technology that combines the phototoxic and immune-stimulating ability of photodynamic therapy with the widespread effectiveness of the immune system to reduce the viability of such as cancer cells and tumors. The nanoparticle compositions of the disclosure combine an immunostimulant with a photosensitizer using a nanoparticle delivery platform.
07/31/14
20140212476
 Method of targeting hydrophobic drugs to vascular lesions patent thumbnailMethod of targeting hydrophobic drugs to vascular lesions
This invention relates to the targeted delivery of hydrophobic drugs or combinations of hydrophobic drugs with photodynamic therapy agents to vascular lesions by complexation of the drugs to blood serum lipoproteins, which have an affinity for and accumulate in such vascular lesions.. .
07/03/14
20140188034
 Therapeutic agent for allergic rhinitis patent thumbnailTherapeutic agent for allergic rhinitis
Provided is a therapeutic agent capable of treating allergic rhinitis in a safe, simple, and noninvasive manner substantially without side effects and physical distress to patients. Provided is a therapeutic agent for allergic rhinitis for 5-aminolevulinic acid-based photodynamic therapy (ala-pdt) comprising 5-aminolevulinic acid (ala) or a derivative thereof, or a salt of the 5-aminolevulinic acid or the derivative as an active ingredient, and used in ala-pdt in which light having a wavelength of 400 nm to 700 nm is irradiated; and particularly provided is a therapeutic agent for allergic rhinitis in a locally applied solution form, a water-soluble ointment-dissolved form, a jelly-dissolved form, or the like.
07/03/14
20140187843
 Radioisotope-photodynamic therapy for cancer treatment patent thumbnailRadioisotope-photodynamic therapy for cancer treatment
The present invention provides compositions and methods for radioisotope-photodynamic therapy for treating cancer. Specifically, the invention relates to compositions and methods for administering a radiation emitter, a rare-earth doped down-converting nanophosphor and a photosensitizer for treating cancer..
06/26/14
20140179918
 Metallocorroles patent thumbnailMetallocorroles
Metallocorrole complexes of third row transition metals (see formula i below) may be used as therapeutic agents, catalysts, components of oxygen detectors, and components of light emitting diodes. In particular, metallocorrole complexes of third row transition metals may be used as improved photosenitizers in photodynamic therapy; as improved catalysts in aziridination, epoxidation, and water splitting reactions; as improved in vivo imaging agents; and as improved components in the emissive layer of oleds.
06/26/14
20140178407
 Methods and compositions for treating conditions of the eye patent thumbnailMethods and compositions for treating conditions of the eye
Provided are methods and compositions for treating ocular conditions characterized by the presence of unwanted choroidal neovasculature, for example, neovascular age-related macular degeneration. The selectivity and sensitivity of, for example, a photodynamic therapy (pdt)-based approach can be enhanced by combining the pdt with an anti-fasl factor, for example, an anti-fasl neutralizing antibody..
06/12/14
20140163451
 Methods and compositions for treating conditions of the eye patent thumbnailMethods and compositions for treating conditions of the eye
Provided are methods and compositions for the photodynamic therapy (pdt) of ocular conditions characterized by the presence of unwanted choroidal neovasculature, for example, neovascular age-related macular degeneration. The selectivity and sensitivity of the pdt method can be enhanced by combining the pdt with an anti-angiogenesis factor, for example, angiostatin or endostatin, or with an apoptosis-modulating factor.
06/12/14
20140163218
 Novel phthalocyanine derivatives for therapeutic use patent thumbnailNovel phthalocyanine derivatives for therapeutic use
There are described phthalocyanine derivates, the pharmaceutical compositions and the medical devices that contain them, possibly in combination with chelating agents, such as edta, useful for treating, by means of photodynamic therapy, diseases characterised by cellular hyperproliferation, microbial infections caused by gram− bacteria, gram+ bacteria and fungi, and for treating various types of infected and non-infected ulcers.. .
06/12/14
20140161773
 Use of an agent that restores tissue perfusion and oxygenation patent thumbnailUse of an agent that restores tissue perfusion and oxygenation
The presently disclosed subject matter provides methods for increasing perfusion in hypoxic regions of tissues in subjects. Also provided are methods for treating diseases and/or disorders associated with hypoxia in subjects, methods for increasing sensitivity of tumors to radiation and/or chemotherapy treatments, methods for delaying tumor growth in subjects, and methods for inhibiting tumor blood vessel growth in subjects.
06/05/14
20140155333
Compositions and methods for cancer treatment using targeted carbon nanotubes
Compositions for detecting and/or destroying cancer tumors and/or cancer cells via photodynamic therapy are disclosed, as well as methods of use thereof. The compositions comprise a linking protein or peptide attached to or otherwise physically associated with a carbon nanotube to form a targeted protein-carbon nanotube complex..
06/05/14
20140154325
In vivo photodynamic therapy of cancer via a near infrared agent encapsulated in calcium phosphate nanoparticles
Nano-encapsulated photosensitizers and their use in the treatment of tumors and/or imaging is described. Preferably, the photosensitizers are encapsulated in a calcium phosphate nanoparticle (cpnp).
06/05/14
20140154181
Rgd-containing peptidomimetics and uses thereof
The invention provides rgd-containing cyclic peptidomimetics; conjugates of said peptidomimetics and a moiety of a payload selected from fluorescent probes, photosensitizers, chelating agents, or cytotoxic agents; and pharmaceutical compositions comprising these conjugates. The conjugates of the invention are useful both for diagnostic purposes and treatment of various diseases, disorders and conditions.
05/08/14
20140128799
Photodynamic therapy using photosensitizing agent or 5-aminolevulinic acid
It is to provide photodynamic therapy (pdt) and photodynamic diagnosis (pdd) which are suitable for the diagnosis and therapy of a part requiring a certain degree of deep penetration, such as subcutaneous cancer and lymph nodes surrounded by blood vessels and fat. This is solved by performing pdt and pdd targeting cancer by administering a composition comprising a photosensitizing agent such as a tetrapyrrole-based compound (photofrin, protoporphyrin ix, etc.) or alas such as 5-aminolevulinic acid (ala), ala methyl ester, ala ethyl ester, ala propyl ester, ala butyl ester, ala pentyl ester, or a hydrochloride, phosphate, or sulfate thereof followed by irradiation with excitation light at a wavelength of 480 to 580 nm..
04/17/14
20140107332
Series of drugs using photofrin to catalyze decomposition of hydrogen peroxide
The present invention relates to a series of new drugs which refer to chemical series capable of catalyzing the decomposition of h2o2 to generate singlet oxygen (1o2). The drugs relate to therapeutic mechanisms, different from traditional photodynamic therapy, in which the specific affinity of photofrin to focus, such as tumors, vascular plaques and skin diseases is utilized.
04/10/14
20140100271
New 5-aminolevulinic acid prodrugs for use in photodynamic therapy and photodynamic diagnosis
And salts thereof, where r1 is an oxime or an alkylated oxime; the alkylated oxime comprises a linear or branched alkyl group of length c1 to c5; and r2 are each independently (a) an unsubstituted or substituted linear or branched alkyl group of chain length c1-7, (b) an aryl substituted alkyl group, where the aryl group is substituted, (c) an alkoxy substituted alkyl group, where the alkoxy group is substituted by a methoxy group or an alkoxy group substituted with an alkoxy group, or (d) an h atom, where the substituents in (a) and (b) are hydroxy, alkoxy, acyloxy, alkoxycarbonyloxy, amino, aryl, nitro, oxo or fluoro groups. The compounds may be used as a medicament..
03/06/14
20140067024
Dual panel photodynamic therapy lamp
A photodynamic therapy lamp includes two lamp modules comprising an array of leds. Each of the lamp modules is movable between a first position in which an angle between the lamp modules is from 157 degrees to 180 degrees, and a second position in which the angle between the lamp modules is from 50 degrees to 70 degrees..
02/27/14
20140056817
Photodynamic therapy or diagnostic agent, using infrared-spectrum light
It is intended to provide a therapeutic and/or diagnostic agent that can be used in photodynamic therapy (pdt) or photodynamic diagnosis (pdd) capable of utilizing infrared-spectrum light such as near-infrared light (nir), infrared light, or far-infrared light, which attains a deep body penetration. The present invention provides a photodynamic therapeutic or diagnostic agent or a photodynamic therapeutic or diagnostic kit for cancer or infectious disease, comprising: a particle (e.g., a lanthanide particle) that emits upconversion luminescence by infrared-spectrum light such as near-infrared light having a wavelength of 0.7 μm to 2.5 μm; and a photosensitizer (e.g., porphyrin) or a 5-aminolevulinic acid group..
02/13/14
20140046290
Synthesis of 2-(4-aminophenyl)benzothiazole derivatives and use thereof
The present invention provides a photodynamic therapy to a patient having at least one tumor comprising the steps of: administering a compound of formula 6 (wherein r1 and r2 are defined as the above) in a pharmaceutically acceptable carrier to the patient; waiting for a sufficient time to allow the administered compound to be taken up by a target tissue having the at least one tumor; and irradiating a region of the patient containing the target tissue, wherein growth of the tumor is inhibited.. .
02/06/14
20140039474
Light diffuser and process for producing the same
A light diffuser, which is particularly suitable for introducing diffuse light into a tissue, is produced by interpenetration of a diffuser material in a liquid state into a boundary layer of a porous shaping material, by which process a diffuser surface is formed having a surface structure which represents essentially a negative of the pore structure of the shaping material and includes undercut structures induced by a surface tension. The light diffuser is e.g.
02/06/14
20140039379
Continuous low irradiance photodynamic therapy system and method
Systems and methods are providing for treating a patient with continuous low irradiance photodynamic therapy. A disclosed method includes applying a photosensitizer to the patient; applying a conformable skin facing light applicator to the patient; and providing continuous low irradiance photodynamic therapy through the light applicator.
02/06/14
20140039322
Diagnostic device, therapeutic device, and uses thereof
Apparatus, method, computing devices, and computer programs related to photodiagnosis and photodynamic therapy, methods of use thereof, and a method for detecting abnormal tissue, are provided.. .
01/30/14
20140031739
Use of fusarochromanone and its derivatives in the diagnosis and treatment of cancer and other diseases
A method of photodynamic therapy to treat diseased cells in an animal is generally provided. According to the method, 5-amino-2,2-dimethyl-6-[3′-(r,s)amino-4′-hydroxy-butan-1-one]-2,3-dihydro-4h-1-benzopyran-4-one or an analog thereof is administered to the animal such that the 5-amino-2,2-dimethyl-6-[3′-(r,s)amino-4′-hydroxy-butan-1-one]-2,3-dihydro-4h-1-benzopyran-4-one or an analog thereof accumulates in the diseased cells.
01/30/14
20140031702
Two-way photodynamic therapy stereo colposcope for diagnosing and treating diseases of the female genital tract
A stereo colposcope having variable linearity filter systems for both the excitation step and the suppression step, and can be used universally with any fluorescent compound or drug, as is the case of photodynamic diagnosis (pdd). The colposcope is a two-way colposcope because the treatment can be administered by an optical system or by a light-producing radio-frequency electrical current with a diathermic effect which facilitates photodynamic treatment.
12/26/13
20130345417
Water soluble anionic bacteriochlorophyll derivatives and their uses
The invention provides anionic water-soluble tetracyclic and pentacyclic bacteriochlorophyll derivatives (bchls) containing at least one, preferably two or three, negatively charged groups and/or acidic groups that are converted to negatively charged groups at the physiological ph, preferably bchls having a group coo<−>, cos<−>, so3<−>, po3<2−>, cooh, cosh, so3h, and/or po3h2 bound through an ester or amide bond to one or more of the positions 17<3>, 13<3>, and 3<2> of the tetracyclic or pentacyclic bchl molecule, for photodynamic therapy and diagnosis.. .
12/19/13
20130338650
Nonlinear optical photodynamic therapy (nlo-pdt) of the cornea
The embodiments include method of nonlinear optical photodynamic therapy of tissue including the steps of providing pulsed infrared laser light for two-photon excited fluorescence tissue exposure, and selectively focusing the pulsed infrared laser light within the tissue at a focal plane to activate a photosensitizing agent to generate free radicals within a highly resolved axial and lateral spatial domain in the tissue. The invention is also directed to an apparatus for performing nonlinear optical photodynamic therapy of tissue including a pulsed infrared laser for providing two-photon excited fluorescence beam tissue exposure, a scanner for selectively and controllably moving the tissue and the beam relative to each other, and optics for selectively focusing the pulsed infrared laser light within the tissue at a point in a focal plane to activate a photosensitizing agent to generate free radicals within a highly resolved axial and lateral spatial domain in the tissue..
11/28/13
20130315989
Method for treating a patient via photodynamic therapy comprising a macromolecular capsule
A composition for photodynamic therapy including a polymer capsule having a diameter of about 10 nm to about 2000 nm synthesized by copolymerization of a flat aromatic compound represented by formula 1 (see the specification) and an organic compound represented by formula 2 (see the specification).. .
11/28/13
20130315834
Nanoprobe comprising gold colloid nanoparticles for multimodality optical imaging of cancer and targeted drug delivery for cancer
The present invention is directed to a nanoparticle loaded with a light sensitive molecule and a method of preparing the nanoparticle, wherein the nanoparticle is a colloidal gold nanoparticle and the light sensitive molecule is non-covalently adsorbed to the surface of the nanoparticle. The present invention is also directed to a nanoprobe comprising the nanoparticle and further comprising a targeting moiety covalently coupled to the surface of the nanoparticle.
11/21/13
20130310734
Catheter for photodynamic therapy
The present invention provides a multi-functional catheter that can be used to irrigate a treatment site located within a body cavity, to suction waste materials from the treatment site, and to deliver a treatment composition in a generally uniform distribution pattern onto the treatment site. The present invention also provides a method to use this multi-functional catheter for various applications including medical applications (e.g., photodynamic therapy treatment of chronic recurrent sinusitis)..
11/14/13
20130304019
Photodynamic therapy system, device and associated method of treatment
As one example, a photodynamic therapy system can include a flexible panel comprising a plurality of light sources distributed across a conformable light delivery surface thereof. The plurality of light sources can be configured to provide a treatment light to achieve a desired therapeutic effect at a predetermined distance from the light delivery surface.
11/07/13
20130296287
Focal photodynamic therapy methods
Improved methods of treating prostate cancer by vascular-targeted photodynamic therapy, and improved methods of planning treatment, are presented using a light density index to plan and guide effective treatment.. .
10/31/13
20130289963
Modelling of the action of an optical fibre in photodynamic therapy treatment, and assistance in the planning of said treatment
A method (200) for planning of a treatment with photodynamic therapy for a patient includes performing a measurement (230) of the volume of the treatment area by volume reconstruction from digital processing of contours inputted directly into a series of digital images of the area being treated, then determining (250) by calculating the number of optical fibers used, their position relative to the brachytherapy grid and their insertion length which optimizes the correspondence of a total theoretical action volume calculated with the measured volume of the treatment area. The total theoretical action volume is calculated based on the position of each fiber, and an elementary theoretical action volume of a fiber corresponding to the volume of a cylinder with predetermined action radius r, and height corresponding to the insertion length of the fiber..
10/31/13
20130287688
Novel compositions and uses of anti-hypertension agents for cancer therapy
Methods and compositions for improving the delivery and/or efficacy of a therapy (e.g., a cancer therapy) are disclosed. In one embodiment, methods and compositions for treating or preventing a cancer (e.g., a solid tumor such as a desmoplastic tumor) by administering to a subject an anti-hypertensive agent, as a single agent or in combination with a microenvironment modulator and/or a therapy, e.g., a cancer therapy (for example, a therapeutic agent or therapy, including immunotherapy (e.g., antibodies, vaccine, cell-based), nanotherapeutics, radiation therapy, photodynamic therapy, low molecular weight chemotherapeutics, molecularly targeted therapeutics and/or oxygen radical) are disclosed..
09/26/13
20130253411
Photodynamic therapy laser
A laser system including: a laser source operable to emit a first and a second laser beam having first and second operating wavelengths, respectively; a fiber optic cable to guide and homogenize the laser beams; an expander to increase the diameter of the laser beams; a cylinder to guide the laser beams and limit respective diameters of the first and second laser beams, wherein the cylinder is positioned after the expander on an optical path of the laser beam; a first optical system to collimate the laser beams, wherein the optical system is positioned after the cylinder on the optical path of the laser beams; a spot-size selector comprising a plurality of apertures, wherein the spot-size selector is positioned after the first optical system on the optical path of the laser beams; and a second optical system to focus the laser beams on a tissue of the patient.. .
09/19/13
20130243741
Renilla/gaussia transfected cells as a light source for in-situ photodynamic therapy of cancer
A method for photodynamic therapy treatment of cancerous cells and tissue is provided. The method comprises administering tumor-trophic cells expressing a luminescent protein to a subject.
09/05/13
20130231604
Halogenated compounds for photodynamic therapy
Halo-organic heterocyclic compounds are described, in which at least two halogen atoms are bound to a nitrogen-containing heterocyclic terminal moiety of the compound, with at least one of such halogen atoms being iodine or bromine. Also described are polymethine dyes based on these heterocyclic compounds, and dendrimeric compounds and conjugates of such polymethine dyes.
08/29/13
20130226069
Acne therapeutic agent and sebum secernent inhibitor which comprise indole-3-alkylcarbo xylicacid, and kits for photodynamic therapy containing the same
The present invention relates to novel uses of indole-3-alkylcarboxylic acid and derivatives thereof as a photosensitizer for the treatment of acne or for the inhibition of sebum secretion. More particularly, the present invention is directed to a photosensitizer for photodynamic therapy, a photodynamic therapy kit and photodynamic therapeutic composition comprising thereof, which contain indole-3-alkylcarboxylic acid being activated by light.
08/15/13
20130211389
Methods and devices for crosslinking of corneal collagen and for treatment of disorders of the eye
Methods and devices for delivering therapeutic or diagnostic energy (e.g., light, ultrasound, ionizing radiation (e.g., x-ray), vibration, heat energy, etc.) into the eye. An energy emitting device is positioned on the eye and used to deliver energy into the eye.
08/15/13
20130210793
Photolabile caged transition metal complexes and methods of using the same
Along with compositions comprising the same and methods of using the same, such as for photodynamic therapy in the treatment of cancer.. .
08/15/13
20130210756
Pheophorbide-alpha conjugates and their uses
The present invention relates to a pheophorbide-α conjugate or its salt, solvate or hydrate. The pheophorbide-α conjugate of the present invention exhibiting fluorescence upon its introduction into cells and degradation inhibits the survival of various cancer cells.
08/08/13
20130202525
Multifunctional nanoplatforms for fluorescence imaging and photodynamic therapy developed by post-loading photosensitizer and fluorophore to polyacrylamide nanoparticles
A composition comprising paa nanoparticles containing a post loaded tetrapyrollic photosensitizer and a postloaded imaging agent and methods for making and using same.. .
08/01/13
20130197611
System and method for optical tomography feedback control of dosimetry for photodynamic therapy (pdt)
Control of interstitial photodynamic therapy (pdt) by means of modulation control and/or optical tomography are disclosed. Accurate reconstruction of optical properties in tissue treated by the pdt is provided.
07/25/13
20130190715
Combination therapy with low dosage strength imiquimod and photodynamic therapy to treat actinic keratosis
This disclosure is directed to the use of complementary or combination photodynamic therapy and topical therapy with a lower dosage strength imiquimod formulation for treating actinic keratosis.. .
07/18/13
20130184674
Treating cancer using electromagnetic fields in combination with photodynamic therapy
A light generating circuit is implanted in a subject's body and aimed at a target region such as a tumor. A photosensitizer is introduced into the target region, and an ac electric field is induced in the region.
07/18/13
20130184637
Treating cancer using electromagnetic fields in combination with photodynamic therapy
A light generating circuit is implanted in a subject's body and aimed at a target region such as a tumor. A photosensitizer is introduced into the target region, and an ac electric field is induced in the region.
07/11/13
20130178787
Dry compositions and devices containing such dry compostions for use in photodynamic therapy or photodynamic diagnosis
This invention relates to dry pharmaceutical compositions comprising an active ingredient which is 5-aminolevulinic acid (5-ala) or a precursor or derivative of 5-ala, or a pharmaceutically acceptable salt thereof. The compositions may be used in the photodynamic treatment (pdt) or photodynamic diagnosis (pdd) of cancer, pre-cancerous conditions and non-cancerous conditions.
07/04/13
20130172863
Determining apparatus and determining method
A photodynamic therapy apparatus as a determining apparatus is the photodynamic therapy apparatus for irradiating a tissue having absorbed photo-sensitive pharmaceutical, the photo-sensitive pharmaceutical absorbing an excitation light and emitting fluorescence, or a tissue absorbing the excitation light and emitting fluorescence, with the excitation light emitted from a tip portion of a laser catheter, including a connector, a light source, and a light detection unit. The laser catheter is capable of being attached/detached to/from the connector.
07/04/13
20130172697
Calculation apparatus and calculation method
[solving means] a photodynamic therapy apparatus as a calculation apparatus is an apparatus for irradiating a tissue having absorbed photo-sensitive pharmaceutical, the photo-sensitive pharmaceutical absorbing an excitation light and emitting fluorescence, with the excitation light emitted from a tip portion of a laser catheter, including a connector, a light source, and a light detection unit. The laser catheter is capable of being attached/detached to/from the connector.
07/04/13
20130172396
Use of derivatives of pentaphyrine as antimicrobial and disinfectant agents
The invention relates to the use of 20-(4-carboxyphenyl)-2,13-dimethyl-3,12-diethyl-[22] pentaphyrine as antibacterial agent in photodynamic treatment. This expanded porphyrin derivatized in position 4 with a carboxyphenyl group proved very active after photo-oxidation both against s.
06/20/13
20130158336
Use of nanoparticles in the photodynamic treatment of tumors and non-destructive testing
A method for generating light intensity inside a tumor to aid in the treatment of diseases such as cancer is disclosed. The light is generated inside the body to perform a modified photodynamic therapy treatment (pdt) that allows treatment of body regions that are inaccessible by normal pdt procedures.
05/16/13
20130123642
Estimating apparatus and estimating method
A photodynamic therapy apparatus as an estimating apparatus is an apparatus for irradiating a tissue having absorbed photo-sensitive pharmaceutical, the photo-sensitive pharmaceutical absorbing an excitation light and emitting fluorescence, with the excitation light emitted from a tip portion of a laser the catheter, including a connector, a light source, and a light detection unit. The laser the catheter is capable of being attached/detached to/from the connector.
04/25/13
20130102906
Illuminator for photodynamic therapy
An apparatus and method for photodynamic therapy or photodynamic diagnosis using an illuminator comprising a plurality of light sources generally conforming to a contoured surface and irradiating the contoured surface with substantially uniform intensity visible light. The light sources may comprise generally u-shaped fluorescent tubes that are driven by electronic ballasts.
04/11/13
20130090592
Use of aminolevulinic acid and derivatives thereof
The invention provides the use of a photosensitiser which is 5-aminolevulinic acid (5-ala) or a derivative (e.g. An ester) of 5-ala, or a pharmaceutically acceptable salt thereof, in the manufacture of a composition for use in methods of photodynamic therapy (pdt) on an animal, wherein said pdt comprises: (a) administering to said animal a composition comprising said photosensitiser; and (b) photoactivating said photosensitiser, and wherein side-effects (e.g.
03/21/13
20130072849
Use of green porphyrins to treat neovasculature in the eye
Photodynamic therapy of conditions of the eye characterized by unwanted neovasculature, such as age-related macular degeneration, is effective using green porphyrins as photoactive agents, preferably as liposomal compositions.. .
02/28/13
20130053699
Apparatus and method for performing photodynamic diagnosis and photodynamic therapy
An apparatus for performing photodynamic diagnosis and photodynamic therapy on a target region that is pre-given with a photosensitizer precursor includes a display unit, an excitation light source operable to irradiate the target region with exciting light so as to excite emission of fluorescence from the target region as a result of fluorescence response of the photosensitizer precursor, an image capturing unit operable to capture a white light image and a fluorescent image of the target region, an image processing unit operable to superimpose the white light image and the fluorescent image into a synthesized image and to provide at least one of the white light image, the fluorescent image and the synthesized image thereto for display on the display unit, and a curing light source operable to irradiate a specified portion of the target region with curing light for treating the specified portion.. .
01/31/13
20130029286
Devices and methods for conforming photodynamic therapy to specific anatomic locations
A device for conforming photodynamic therapy to a specific anatomic location (e.g., in the oral cavity) conforms the radiation to the target tissue surface and avoids delivering light to the rest of the oral cavity. Embodiments can include a body of oral impression material molded to conform to the anatomic surface, a light pipe, a freeform reflector formed on a surface of the optical body, or a light guide having a textured surface to direct light to an opposing output window.
01/10/13
20130012754
Microwave induced photodynamic therapy
A method of administering photodynamic therapy includes using a microwave frequency-sensitive light-emitting polymer as a light source to excite a administered photosensitizer to exert cytotoxicity in situ at a site containing undesired or diseased tissue.. .
01/03/13
20130004419
Carbonylporphyrins and uses thereof
The present invention is directed to low toxicity boronated compounds and methods for their use in the treatment, visualization, and diagnosis of tumors. More specifically, the present invention is directed to low toxicity carborane-containing porphyrin compounds with halide, amine, or nitro groups and methods for their use particularly in boron neutron capture therapy (bnct), x-ray radiation therapy (xrt), and photodynamic therapy (pdt) for the treatment of tumors of the brain, head and neck, and surrounding tissue.


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Photodynamic Therapy topics: Photodynamic Therapy, Sensitizer, Fluorescence, Cancer Cells, Cancer Cell, Antibodies, Antimicrobial, Therapeutics, Hypertensive, Hypertension, Desmoplastic, Immunotherapy, Radiation Therapy, Digital Processing, Optical Fiber

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