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Photodynamic Therapy

Photodynamic Therapy-related patent applications - as published by the U.S. Patent and Trademark Office (USPTO).


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Polymers and oligomers with aggregation-induced emission characteristics for imaging and image-guided therapy
The Hong Kong University Of Science And Technology
June 15, 2017 - N°20170168041

A fluorophore or conjugated polymer with aggregation-induced emission characteristics useful for drug tracking and delivery, identification and labeling of biological subjects, such as cells or parts of a cell, as well as for imaging, and image-guided photodynamic therapy are described herein.
Synthesis and composition of photodynamic therapeutic agents for the targeted treatment of cancer
The Hong Kong University Of Science And Technology
May 25, 2017 - N°20170145035

The present invention describes new compounds that are useful for image-guided surgery and photodynamic therapy. In particular the compounds may be targeted to the nucleus or the mitochondria after compounds were delivered to diseased tissues such as cancer using a ligand that target receptor that express on the diseased tissue and followed by receptor mediated endocytosis and provide effective activity ...
Water soluble anionic bacteriochlorophyll derivatives and their uses
The Hong Kong University Of Science And Technology
May 25, 2017 - N°20170143988

The invention provides anionic water-soluble tetracyclic and pentacyclic bacteriochlorophyll derivatives (bchls) containing at least one, preferably two or three, negatively charged groups and/or acidic groups that are converted to negatively charged groups at the physiological ph, preferably bchls having a group coo<−>, cos<−>, so3<−>, ...
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Adjustable illuminator for photodynamic therapy and diagnosis
Dusa Pharmaceuticals, Inc.
April 20, 2017 - N°20170106205

An adjustable illuminator for photodynamically diagnosing or treating a surface includes a plurality of first panels and at least one second panel. The plurality of first panels have wider widths and the at least one second panel has a narrower width. The narrower width is less than the wider widths. The illuminator further includes a plurality of light sources, each ...
Diagnostic device, therapeutic device, and uses thereof
Cerca Solutions, Llc
April 13, 2017 - N°20170100073

Apparatus, method, computing devices, and computer programs related to photodiagnosis and photodynamic therapy, methods of use thereof, and a method for detecting abnormal tissue, are provided,
Novel polygonum cuspidatum extracts and their use as photodynamic inactivating agents
Photodynamic Inc.
April 06, 2017 - N°20170095521

The present invention describes extracts of polygonum cuspidatum and related compositions that are capable of photodynamic inactivation (pdi) of microorganisms such as bacteria, viruses, fungi, and protozoa, and capable of killing or inactivating cancer cells. The present invention further describes methods of using said polygonum cuspidatum extracts and photodynamic inactivation (pdi) as a therapy for the treatment of microbial infection ...
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Photodynamic therapy, formulation usable for this purpose, and method for the production and use thereof
Sanochemia Pharmazeutika Ag
March 30, 2017 - N°20170087249

A treatment of cancer, such as, for example, bladder cancer, uses a formulation that contains sodium hypericinate that is bonded to polyvinylpyrrolidone or complexed with polyvinylpyrrolidone.
Irradiation device
Photocure Asa
March 16, 2017 - N°20170072217

An irradiation device for insertion into an orifice of the body for providing photodynamic therapy or diagnosis comprises: a housing 1, 21, 31, 51, 61, 71 adapted to be fully inserted and secured in the orifice, the housing 1, 21, 31, 51, 61, 71 enclosing an led lamp system 5, 25, 35, 45, 54, 62, 72 and a power source 41, 68, 78, for powering the led lamp system 5, 25, 35, 45, 54, 62, 72, wherein the device is independently operational while located within the orifice.
Ultraslow light and nondegenerate phase conjugation-based real-time, non-invasive, in-vivo deep-tissue optical imaging apparatus, photodynamic therapy ...
Gwangju Institute Of Science And Technology
March 02, 2017 - N°20170055838

The present invention provides a method which can significantly increase the signal-to-noise ratio of an ultrasound-modulated optical signal by overcoming the shallow depth problem of in vivo optical imaging in existing optical imaging by use of a quantum optical phenomenon based on ultraslow light and nondegenerate phase conjugation and which can be applied directly not only to medical optical imaging, ...
Photodynamic therapy using in situ nonlinear photon upconversion of nir light by biological medium
The Research Foundation For The State University Of New York
February 23, 2017 - N°20170050045

Photodynamic therapy methods using near infrared light and visible-light-absorbing photosensitizers and methods of generating visible light in an individual. The methods use upconverted incident near infrared light, for example, to excite the photosensitizer or facilitate drug delivery. The methods can be carried out on humans and non-human animals.
5-aminolevulinic acid conjugated quantum dot nanoparticle
Nanoco Technologies Ltd.
February 23, 2017 - N°20170049891

A 5-aminolevulinic acid conjugated quantum dot nanoparticle is useful for treating cancer by administering the 5-aminolevulinic acid conjugated quantum dot nanoparticle in photodynamic therapy as a precursor of both a fluorescence label and a photosensitizer.
Methods and systems for detecting sub-tissue anomalies
The Board Of Regents Of The University Of Texas System
February 23, 2017 - N°20170049417

A diagnostic imaging device includes a probe that uses both an ultrasound transducer and frequency-domain diffuse optical imaging (fd-doi) to assist with locating and diagnosing sub-tissue anomalies. According to one aspect, the diagnostic imaging device relates to a clip-on cap that can be utilized with existing ultrasound transducers. The diagnostic imaging device described herein can be utilized for image-guided needle ...
Apparatus and method for multiwavelength photodynamic therapy
Theralase Technologies, Inc.
February 16, 2017 - N°20170043179

A method for treating a condition in a tissue, includes the steps: (1) providing a ps within the tissue; (2) irradiating the tissue containing the ps with a first light of a first wavelength; and (3) irradiating the tissue containing the ps with a second light of a second wavelength so as to treat the condition in the tissue, wherein: (a) the ps ...
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Metal-glycoprotein complexes and photodynamic therapy of immune privileged sites with same
Theralase Technologies, Inc.
February 16, 2017 - N°20170042976

Compositions of the invention include glycoproteins, such as transferrin, and metal-based coordination complexes, which are preferably chemotherapeutic compounds and more preferably tunable photodynamic compounds. The compositions are useful as in vivo diagnostic agents, and as therapeutic agents for treating or preventing diseases including those that involve hyperproliferating cells in their etiology, such as cancer. Compositions of the invention are further ...
Lung targeting dual drug delivery system
Rutgers, The State University Of New Jersey
February 16, 2017 - N°20170042818

The american cancer society estimated that in 2009, 1,479,350 new cancer cases would be diagnosed in the united states of which 219,440 would be lung and bronchus related. The standard treatments for nsclc include surgery, chemotherapy, radiation, laser and photodynamic therapy, all with various success rates depending on the stage of the cancer. National cancer institute assesses, however, that results of standard treatment ...
Methods and compositions for treating conditions of the eye
Massachusetts Eye And Ear Infirmary
February 09, 2017 - N°20170035883

Provided are methods and compositions for treating ocular conditions characterized by the presence of unwanted choroidal neovasculature, for example neovascular age-related macular degeneration. The selectivity and sensitivity of, for example, a photodynamic therapy (pdt)based approach can be enhanced by combining the pdt with an anti-fasl factor, for example, an anti-fasl neutralizing antibody.
Uniform core-shell tio2 coated upconversion nanoparticles and use thereof
National University Of Singapore
January 05, 2017 - N°20170000887

An upconversion nanoparticle (ucn) coated with a layer of semiconductor material is disclosed. The ucn core acts as a nanotransducer to convert near infrared (nir) to visible and/or ultraviolet (uv) light while the semiconductor shell serves as a photocatalyst. Upon excitation by nir light, the ucn upconverts nir light to uv and/or visible light of different wavelengths. Spectral ...
Dual panel photodynamic therapy lamp
Photocure Asa
December 22, 2016 - N°20160367832

A photodynamic therapy lamp includes two lamp modules comprising an array of leds. Each of the lamp modules is movable between a first position in which an angle between the lamp modules is from 157 degrees to 180 degrees, and a second position in which the angle between the lamp modules is from 50 degrees to 70 degrees.
Combination artemisinin and chemiluminescent photodynamic therapy and uses therefor
Washington University
December 22, 2016 - N°20160367674

Photodynamic therapy-based methods of treating diseases such as cancer and malaria are disclosed. These methods include administering 5-aminolevulinic acid (ala), luminol and artemisinin (art). Art and ala administered in combination with luminol can kill malaria parasites without host toxicity. In some aspects, the methods further include administration of a luminol enhancer such as 4-iodophenol. The disclosed methods can also be ...
Composition for prevention or treatment of treatment-resistant cancer
Washington University
December 15, 2016 - N°20160361418

[solution] a preventive or therapeutic composition for a therapy-resistant cancer having therapy-resistant cancer cells, which is for use in photodynamic therapy, wherein the composition comprises alas.
Pulse photodynamic treatment of skin conditions
Galderma Research & Development
December 01, 2016 - N°20160346392

A pulse photodynamic therapy (or pulse pdt) treatment of skin complaints is described herein. The skin complaint being treated can be actinic keratosis (ak) or a basal cell carcinoma (bcc).
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