This page is updated frequently with new Peritoneal-related patent applications.
|| List of recent Peritoneal-related patents
|Method for identifying a bacterial infection|
Method for identifying a bacterial infection the present application concerns a method for identifying the nature of a bacterial infection from a peritoneal sample, in particular, whether it is a gram-negative or gram-positive infection, based upon the determination of one or more cellular and/or humoral markers in a sample.. .
University College Cardiff Consultants Limited
|Targeted polymeric inflammation-resolving nanoparticles|
Sub-100 micron multimodal nanoparticles have four main components: 1) a target element (peptides, lipids, antibodies, small molecules, etc.) that can selectively bind to cells, tissues, or organs of the body; 2) a diagnostic agent such as a fluorophore or nmr contrast agent that allows visualization of nanoparticles at the site of delivery and/or a therapeutic or prophylactic agent; 3) an outside “stealth” layer that allows the particles to evade recognition by immune system components and increase particle circulation half-life; and 4) a biodegradable polymeric material, forming an inner core which can carry therapeutics and release the payloads at a sustained rate after systemic, intraperitoneal, or mucosal administration. These particles possess excellent stability, high loading efficiency, multiple agent encapsulation, targeting and imaging.
The Trustees Of Columbia University
|Method and spinal cooling|
A method for exchanging heat with a patient's spinal column incident to spinal surgery or to relieve a patient for a hypoxia condition of the spine. A closed loop heat exchange catheter is percutaneously advanced into the retroperitoneal space of the patient or into the vasculature, and then heat exchange fluid is circulated through the catheter to cool the spinal column..
Zoll Circulation, Inc.
|Peritoneal dialysis system and method|
A peritoneal dialysis machine that includes a base, a boiling vessel, a condenser, a fluid storage vessel, a sterilizing uv lamp, a fluid mixer, a dialysate cassette, a boiling vessel demineralizing system, and an optional fluid storage vessel rinsing system. The peritoneal dialysis machine automatically generates a predetermined volume of distilled water each day.
|System for producing tissue-engineered material|
A system for producing a tissue-engineered material includes a hollow member and a mechanical stimulating unit. The hollow member is adapted to be implanted in a peritoneal cavity, and is to be positioned in the peritoneal cavity in a manner that a part of the hollow member contacts an inner wall surface of the peritoneal cavity for enabling formation of a biological tissue that encapsulates the hollow member.
National Cheng Kung University
|Pyridine derivatives as rearranged during transfection (ret) kinase inhibitors|
This invention relates to novel compounds which are inhibitors of the rearranged during transfection (ret) kinase, to pharmaceutical compositions containing them, to processes for their preparation, and to their use in therapy, alone or in combination, for the normalization of gastrointestinal sensitivity, motility and/or secretion and/or abdominal disorders or diseases and/or treatment related to diseases related to ret dysfunction or where modulation of ret activity may have therapeutic benefit including but not limited to all classifications of irritable bowel syndrome (ibs) including diarrhea-predominant, constipation-predominant or alternating stool pattern, functional bloating, functional constipation, functional diarrhea, unspecified functional bowel disorder, functional abdominal pain syndrome, chronic idiopathic constipation, functional esophageal disorders, functional gastroduodenal disorders, functional anorectal pain, inflammatory bowel disease, proliferative diseases such as non-small cell lung cancer, hepatocellular carcinoma, colorectal cancer, medullary thyroid cancer, follicular thyroid cancer, anaplastic thyroid cancer, papillary thyroid cancer, brain tumors, peritoneal cavity cancer, solid tumors, other lung cancer, head and neck cancer, gliomas, neuroblastomas, von hippel-lindau syndrome and kidney tumors, breast cancer, fallopian tube cancer, ovarian cancer, transitional cell cancer, prostate cancer, cancer of the esophagus and gastroesophageal junction, biliary cancer, adenocarcinoma, and any malignancy with increased ret kinase activity.. .
Glaxosmithkline Intellectual Property Development Limited
|Dialysis implant and methods of use|
A device and methods for treating renal failure are disclosed. One embodiment of the device is an implantable peritoneal dialysis device.
Sequana Medical Ag
|Methods for reducing fibrosis induced by peritoneal dialysis|
The disclosure relates to a method of preventing, inhibiting, or reducing fibrosis, the incidence of fibrosis or the progression of fibrosis associated with peritoneal dialysis, during or after peritoneal is administered. More specifically, the methods relates to using intraperitoneal administration of activated protein c (apc) possessing cytoprotective or anti-inflammatory activity, to reduce the incidence or progression of fibrosis associated with peritoneal dialysis.
Saint Louis University
|Axially split foam peritoneal dialysis catheter design with functional coatings|
The present disclosure provides a dialysis device for peritoneal dialysis. The device comprises a proximal tubular portion comprising a plurality of proximal lumens and a distal tubular portion comprising a plurality of independent tubes.
Cook Medical Technologies Llc
|Transfer catheter for ultraviolet disinfection|
Disclosed herein are devices and methods related to uv disinfection of a transfer catheter during peritoneal dialysis. The transfer catheter comprises a first and second end, the second end comprising a transfer valve.
A medical device, preferably for peritoneal dialysis, is described which comprises a film tube.. .
Auto-graft bio-synthetic mesh for ventral and parastomal hernia repair and attachment as well as a suture clip
An auto-graft bio-synthetic mesh and a method of application for wound closure is described. The mesh is utilized for wound closure wherein an abdominal incision is effected through the peritoneum and the rectus abdominal sheath of the rectus muscle such as when repairing ventral or paracoslostomy hernias.
Antimicrobial housing and cover for a medical device
A method for immobilizing dyes and antimicrobial agents on a polymeric cover or housing for a medical device is disclosed and described. The surface may be that of a catheter, a connector, a drug vial spike, a bag spike, a prosthetic device, an endoscope, a surface of an infusion pump, a key pad, a touch screen or a handle.
Baxter Healthcare S.a.
Pharmaceutical composition containing conventional liposomes and prolonged-circulation liposomes for the treatment of visceral leishmaniasis
The present invention relates to a pharmaceutical composition for treating visceral leishmaniasis, characterized in that it comprises the association of conventional liposomes and prolonged-circulation liposomes with a leishmanicidal-drug delivery system. Said composition may be used in the preparation of a medicinal product for treating leishmaniasis and may be administered intramuscularly, subcutaneously, intraperitoneally or intravenously.
FundaÇao De Amparo A Pesquisa Do Estado De Minas Gerais- Fapemig
Method of adsorption of ions from a dialysis fluid
A method of adsorption of potassium ions from a peritoneal dialysis fluid, which has been removed from the peritoneal cavity of a patient performing peritoneal dialysis for subsequent recirculation and introduction into the peritoneal cavity of the patient. The peritoneal dialysis fluid is passed through a potassium adsorbent, such as a zeolite, which has been pre-equilibrated with an equilibration fluid comprising na+, ca2+, mg2+, cl−, lactate, in substantially the same concentration as in the peritoneal dialysis fluid and which equilibration fluid lacks k+.
Laparoscopic tool with obturator
A laparoscopic device with obturator. The device facilitates extraction of specimens from a female subject's abdominal cavity through the subject's vagina by also facilitating the suturing of a mesh to the anterior and posterior walls of the subject's vagina.
Tissue debris and blood collection device and methods of use thereof
Protective barrier for laparoscopy is provided and comprises bag with closed bottom, wall(s), and open end. Bag may comprise drawstring and/or optional flexible stay(s), in internal channel around periphery of open end of bag.
Laparoscopic Innovations Llc
A medical device tunneling system, and a method of using the same, to subcutaneously route trocars, also commonly referred to as tunnelers, or introducers, having a cannula, stylet, and a guidewire stylet, inside a patient during a surgical procedure, such as a ventriculoperitoneal hydrocephalus shunt implantation, from a proximal entry point to a distal end point, in order to subcutaneously route and implant a medical device, such as shunt tubing, in a patient.. .
Chondroitin for use in medicine
Chondroitin, a metabolic intermediate of chondroitin sulphate biosynthesis in mammals and other living organisms, possesses biological properties different from those of chondroitin sulphate, and can be advantageously used for applications in the pharmaceutical, nutraceutical, cosmeceutical and medical device fields. Chondroitin has biostimulating, anti-inflammatory and anti-microbial activity and can be used in the treatment of osteoarthritis, eye disorders, interstitial cystitis, lung disorders, inflammatory disorders in general, oncological disorders, peritoneal dialysis, tissue biorevitalisation and wound repair, as a skin filler, and as bioresorbable scaffolds..
Reducing post-operative adhesion formation with intraperitoneal glutamine
Intraperitoneal administration of glutamine to reduce adhesions in the peritoneum of a patient.. .
Ade Therapeutics Inc.
Peritoneal dialysis fluid
The present invention is a sterile peritoneal dialysis fluid, including an acidic first liquid containing 60.0 to 94.0 g/l of icodextrin and 0 to 2.34 g/l of sodium chloride, and an alkaline second liquid containing an alkaline ph regulator, in which the first liquid after sterilization has a ph of 5.0 to 5.5, the second liquid after sterilization has a ph of 6.5 to 7.5, and a mixture of the first liquid and the second liquid after sterilization has a ph of 6.0 to 7.5. The present invention can provide a peritoneal dialysis fluid containing icodextrin, in which the stability of icodextrin during the heat sterilization and the subsequent storage can be improved to the maximum, and the ph of the peritoneal dialysis fluid is close to the physiological range..
Terumo Kabushiki Kaisha
Partially absorbable fiber-reinforced composites for controlled drug delivery
This invention describes a partially absorbable, fiber-reinforced composite in the form of a ring, or a suture-like thread, with modified terminals for use as a controlled delivery system of at least one bioactive agent, wherein said composite comprising an absorbable fiber construct capable of providing time-dependent mechanical properties of a biostable elastomeric matrix containing an absorbable microparticulate ion-exchanger to modulate the release of the bioactive agent(s) for a desired period(s) of time at a specific biological site; this can be a vaginal canal, peritoneal cavity, scrotum, prostate gland, an ear loop or subcutaneous tissue. Such drug delivery systems can be used for the local administration of at least one bioactive agent, including those used as contraceptive, antimicrobial, anti-inflammatory and/or antiviral agents as well as for cancer treatment..
Peritoneal dialysis fluid
The present invention is a sterile peritoneal dialysis fluid, including an acidic first liquid containing only icodextrin and 0 to 2.34 g/l of sodium chloride, and an alkaline second liquid containing an alkaline ph regulator, in which the first liquid after sterilization has a ph of 5.0 to 5.5, the second liquid after sterilization has a ph of 6.5 to 7.5, and a mixture of the first liquid and the second liquid after sterilization has a ph of 6.0 to 7.5. The present invention can provide a peritoneal dialysis fluid containing icodextrin, in which the stability of icodextrin during the heat sterilization and the subsequent storage can be improved to the maximum, and the ph of the peritoneal dialysis fluid is close to the physiological range..
Terumo Kabushiki Kaisha
Fluid line autoconnect medical treatment system
A medical infusion fluid handling system, such as an automated peritoneal dialysis system, may be arranged to de-cap and connect one or more lines (such as solution lines) with one or more spikes or other connection ports on a fluid handling cassette. This feature may reduce a likelihood of contamination since no human interaction is required to de-cap and connect the one or more lines and the one or more spikes.
Deka Products Limited Partnership
Optimizing peritoneal dialysis using a patient hand-held scanning device
A handheld personal communication apparatus for dialysis includes: a reader to (i) read a marking displayed on a dialysis fluid container to acquire data concerning at least one of a dialysis fluid type or a dialysis fluid volume from the marking, and/or (ii) receive a patient weight signal from a weight scale; a processor using at least one of the dialysis fluid type, dialysis fluid volume, or patient weight to determine a dialysis dwell time for at least one cycle of a dialysis therapy, the dialysis dwell time being a time to achieve, over the at least one cycle, at least one of (a) a specified ultrafiltrate level, (b) a urea removal level, or (c) a creatinine removal level; and an output interface providing an indication to the patient of a completion of the dialysis dwell time.. .
Baxter Healthcare S.a.
Portal and management of dialysis therapy
System and method for point-of-care monitoring of neutrophils in a peritoneal dialysis sample with the use of a microfluidic system. The immunoassay based chip is configured to bound neutrophils to a microfluidic channel surface while leaving auxiliary cells and particles unattached and suspended in the sample and flushable with a wash buffer.
Therapy with clostridium perfringens enterotoxin to treat ovarian and uterine cancer
The invention discloses high levels of receptors for clostridium perfringens enterotoxin (cpe) have been found in ovarian cancer and uterine cancer tissue samples. In addition, successful in vivo treatment of a mouse model of ovarian cancer with intraperitoneal injection of cpe is disclosed.
Viral fusion protein treatment for ccr8 mediated diseases
Compositions, methods, and kits are provided for treating ccr8 mediated diseases with applicability to atopic dermatitis and potential applicability to asthma, prurigo nodularis, nummular dermatitis, neurodeimatitis, and lichen simplex chronicus and some lymphomas, multiple sclerosis, acquired immunodeficiency disease, peritoneal adhesions, kaposi's sarcoma and atherogenesis—the expression of all of which, at least in part, is mediated by cells expressing the chemokine receptor ccr8. The compositions include proteins and fusion proteins from molluscum contagiosum virus (mcv) or variants, analogs and derivatives thereof which exhibit inhibitory activity.
Liposome composition for use in peritoneal dialysis
The present invention is directed to a liposome composition for use in the peritoneal dialysis of patients suffering from endogenous or exogenous toxicopathies, wherein the ph within the liposomes differs from the ph in the intraperitoneal cavity and wherein the ph within the liposome results in a liposome-encapsulated charged toxin. The invention also relates to a pharmaceutical composition comprising said liposomes.
Hemodialysis and peritoneal dialysis systems having electrodialysis and electrodeionization capabilities
Systems and methods for hemodialysis or peritoneal dialysis having integrated electrodialysis and electrodeionization capabilities are provided. In an embodiment, the dialysis system includes a carbon source, a urease source, an ed/edi unit.
Baxter Healthcare S.a.
Systems and methods for performing peritoneal dialysis
Systems and methods for providing multiple pass continuous flow dialysis are provided. In an embodiment, a system for providing peritoneal dialysis includes a catheter in communication with a peritoneal cavity, a fluid loop in fluid communication with the catheter and capable of circulating a therapy fluid into, through and out of the patient's peritoneal cavity, a multi-line fluid circuit, the multi-line fluid circuit in fluid communication with the fluid loop and including a bypass line coupled to a discharge fluid line, and a cycler including a plurality of valves, the cycler programmed to operate the plurality of valves to selectively (i) discharge therapy fluid from the multi-line fluid circuit via the discharge fluid line or (ii) bypass the discharge fluid line via the bypass line and circulate the therapy fluid a plurality of times through the fluid loop prior to exiting the multi-line fluid circuit via the discharge fluid line..
Baxter Healthcare S.a.
Composite absorbable/biodegradable rings for controlled drug delivery
A fiber-reinforced composite ring for the controlled release of at least one bioactive agent includes a biocompatible matrix reinforced with absorbable/biodegradable fibers capable of providing the mechanical properties needed for inserting and maintaining the ring in a body cavity for a desired period of time. Such ring system as can be used for the intravaginal, intraperitoneal, and subcutaneous delivery of at least one bioactive agent, including those used as contraceptives, antimicrobial agents, and/or antiviral agents, as well as those for the treatment of cancer..
Method of inexpensive transepithelial dialysis with hot water bath and sorbents
Current technologies to treat end stage renal disease (esrd) include peritoneal dialysis, hemodialysis and transplantation all of which are expensive. This invention is an inexpensive method to decrease body toxins that requires immersion of a body in a hot water bath with sorbents.
Method of mending a groin defect
A method of mending a groin defect such as an indirect inguinal hernia, a direct inguinal hernia, and/or a femoral hernia. A space between the external oblique aponeurosis and the internal oblique aponeurosis is dissected superiorly and laterally to create a site for receiving a lateral portion of a prosthetic repair patch.
Bard Shannon Limited
Device having electrodes for bio-impedance measurement for dialysis
Electrodes for a bio-impedance measuring device or a body composition monitor, the electrodes being integral with or being attached to a surface of at least one device belonging to a group of electronic and/or non-electronic devices used in the preparation of a dialysis treatment or during dialysis, in particular during peritoneal dialysis, the group preferably consisting of organizers of a continuous ambulatory peritoneal dialysis system (capd), automated peritoneal dialysis devices, automated peritoneal dialysis-cyclers (apd-cycler), bioelectrical impedance analyzers (bia), body composition monitors (bcm), hand-held electrodes holders for the electrodes, and dialysis apparatuses. Devices and methods used during dialysis are also described..
Fresenius Medical Care Deutschland Gmbh
A connection device, to connect two ends of respective ducts to another flexible duct in the field of the peritoneal dialysis including a closed container containing two nozzle-like terminal ends of a y-shaped branch of a flexible duct; a removable connection member configured to be engaged/disengaged on the closed container, containing the ending portions of the respective ducts shaped to couple/uncouple with the nozzle-like terminal ends, a distal end of the container and the connecting member are shaped to couple according to a guiding scheme with prismatic joint; a closure with mobile walls on the closed container is actuated in opening and closing by the contact of a projecting septum of the connection member upon the connection/disconnection between the closed container and the connection member; and a closure with removable tear film arranged at the ending portions of the ducts to close the respective sections opened inside the connection member.. .
Glomeria Therapeutics S.r.l.
Solution for peritoneal dialysis
The present invention further relates to a twin-chambered pouch consisting of a plastic pouch with at least one first chamber and a second chamber, the first single solution being included in the first chamber and the second single solution being included in the second chamber.. .
Devices, systems, and methods for diagnosing and delivering therapeutic interventions in the peritoneal cavity
A device and system are described that are capable of isolating at least one targeted tissue and forming an anastomosis between two internal body structures though a completely endoscopic procedure. Further, the device and system described generally comprise two tubular members that are capable of moving in a telescopic fashion relative to one another.
Peritoneal dialysis connection using ultraviolet light emitting diodes
peritoneal dialysis systems and methods are provided by the present disclosure. In a general embodiment, a peritoneal dialysis system includes a peritoneal dialysis fluid supply, a supply line in fluid communication with the peritoneal dialysis fluid supply, the supply line terminating at a supply connector, a patient connector in fluid communication with a patient's indwelling catheter, and a device configured to be placed around at least one of the supply connector and the patient connector during a connection of the supply connector and the patient connector, the device including an ultraviolet (“uv”) transmissive material to allow uv energy to be directed inwardly through the device towards a mating surface of the at least one of the supply connector and the patient connector during the connection of the supply connector and the patient connector..
Baxter Healthcare S.a.
Method of placing a drainage catheter system
The present disclosure describes a single incision method of placing a drainage catheter in the peritoneal cavity.. .
Therapeutic methods for peritoneal carcinomatosis
Described herein are methods and medicaments useful for treating peritoneal carcinomatosis by administering anti-ctgf agents, particularly anti-ctgf antibodies. Methods for prognosing individuals with perinoteal carcinomatosis are also provided.
Body fluid expanders comprising n-substituted aminosulfonic acid buffers
A buffered body fluid expander solution, in which the buffer is a physiologically acceptable buffer that is not an inorganic phosphate buffer, comprises calcium ions and magnesium ions at a concentration ratio of 5:1 to 1:1. The solutions are useful for the manufacture of medicaments and blood volume expanders, for treating hypovolemia or for treating the loss of extracellular and interstitial fluid in subjects suffering with burns, for treating respiratory and/or metabolic acidosis in a subject, for perfusion of the abdominal cavity during peritoneal dialysis of a subject with acute renal failure or an acute toxicity condition, for preventing and/or ameliorating reperfusion injury, and for delivering a therapeutic, test and/or synergistic agent to a subject, including a biological agent, such as at least one stem cell, peptide or genomic derived protein..
System and monitoring and control of ultrafiltration volume during peritoneal dialysis using segmental bioimpedance
A peritoneal dialysis (pd) system for infusing a volume of pd solution into a patient's peritoneal cavity in order to perform peritoneal dialysis on the patient includes a peritoneal cavity monitor (pcm) that measures this volume of fluid in the patient's peritoneal cavity by segmental bioimpedance spectroscopy (sbis), to thereby determine an ultrafiltration volume of fluid in the patient's peritoneal cavity, and a switch, controlled by the pcm, for filling the patient's peritoneal cavity and draining the patient's peritoneal cavity when the ultrafiltration volume is unchanged over time, significantly decreased, or decreasing at a significant rate.. .
Methods and devices for diagnostic and therapeutic interventions in the peritoneal cavity
A novel approach to diagnostic and therapeutic interventions in the peritoneal cavity is described. More specifically, a technique for accessing the peritoneal cavity via the wall of the digestive tract is provided so that examination of and/or a surgical procedure in the peritoneal cavity can be conducted via the wall of the digestive tract with the use of a flexible endoscope.
Apollo Endosurgery, Inc.
Exterior cap of transfer set for peritoneal dialysis
An exterior cap of transfer set for peritoneal dialysis, including: a cylindrical cap unit to which the end connector of the peritoneal transfer set is coupled; a guide unit that is coupled to the cap unit, extends to the peritoneal transfer set to provide an expanding internal space, and guides the end connector of the peritoneal transfer set into the cap unit; and a coupling-separating unit that combines the cap unit and the guide unit with each other and separates the cap unit and the guide unit in accordance with selection of a user.. .
Research Cooperation Foundation Of Yeungnam University
Dipeptide mimetics of ngf and bdnf neurotrophins
The invention relates to compounds having either agonist or antagonist activities for the neurotrophins ngf and bdnf and represented by monomeric or dimeric substituted dipeptides that are analogs of the exposed portions of loop 1 or loop 4 regions of these neurotrophins near or at a beta-turn of the respective loop. N-acylated substituents of these dipeptides are biostereoisomers of the amino acid residues preceding these dipeptide sequences in the neurotrophin primary structure.
Uchrezhdenie Rossiiskoi Akademii Meditsynskikh Nauk Nauchno-issledovatelsky Institut Farmakologii
User wearable device for carrying peritoneal dialysis catheter
Improvements in an easily wearable catheter. A housing secures the components of the catheter, i.e.
Line leaf inula flower lactone a and methods for preparing and using the same for treating myocarditis
The compound shows positive therapeutic activity against coxsackie virus and significant dose dependent correlation. The line leaf inula flower lactone a prevents disease in mouse models of experimental autoimmune myocarditis and onset of the process by intraperitoneal injection of a dose of 20 mg/kg/d.
Peritoneal topics: Peritoneal, Peritoneal Dialysis, Peritoneal Cavity, Dialysis System, Intraperitoneal, Abdominal Cavity, Hemodialysis, Anastomosis, Wireless Communication Device, Colorectal, Hydrogen Sulfide, Sulfonamide, Ultraviolet, Ultraviolet Light, Subcutaneous
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