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Peritoneal patents



      

This page is updated frequently with new Peritoneal-related patent applications.




Date/App# patent app List of recent Peritoneal-related patents
06/23/16
20160175141 
 Method and system for producing and delivering airless medical ice slurry to induce hypothemia patent thumbnailnew patent Method and system for producing and delivering airless medical ice slurry to induce hypothemia
The present invention relates to a method and system for producing and delivering sterile, airless, and highly loaded ice slurry for inducing therapeutic hypothermia. The method is capable of producing and delivering ice slurry in a patient to induce hypothermia through internal and external cooling methods such as subcutaneous, intravascular, intraperitoneal, gastrointestinal, and lung methods.

06/16/16
20160166805 
 Cinching peritoneal dialysis catheter patent thumbnailCinching peritoneal dialysis catheter
Described are peritoneal catheter devices and methods for positioning these devices in a medical patient. The peritoneal catheter includes a catheter tube having a proximal end portion opposite a distal end portion, a stationary flange attached to the catheter tube near the distal end portion, and a mobile flange positioned on the catheter tube between the stationary flange and the proximal end portion.
Cook Medical Technologies Llc


06/16/16
20160166608 
 Methods of treating cancer with high potency lipid-based platinum compound formulations administered intraperitoneally patent thumbnailMethods of treating cancer with high potency lipid-based platinum compound formulations administered intraperitoneally
One aspect of the invention relates to methods of treating cancer in a patient comprising administering intraperitoneally to a patient in need thereof a cancer treating effective amount of a composition comprising a lipid-complexed platinum compound wherein the concentration of the platinum compound of the lipid-complexed platinum compound composition is greater than about 1.2 mg/ml. Another aspect of the invention relates to lipid-complexed platinum compound compositions where the concentration of the platinum compound is greater than about 1.2 mg/ml..
Insmed Incorporated


05/26/16
20160144094 
 Compositions, methods, and devices for dialysis patent thumbnailCompositions, methods, and devices for dialysis
Compositions of peritoneal dialysis solutions and metabolizing enzymes, and their uses to treat disorders associated with elevated levels of metabolites are disclosed. Animal models of hyperoxalemia are also disclosed..
Allena Pharmaceuticals, Inc.


05/26/16
20160144093 
 Medical treatment system and methods using a plurality of fluid lines patent thumbnailMedical treatment system and methods using a plurality of fluid lines
A medical treatment system, such as a peritoneal dialysis system, may include a control and other features to enhance patient comfort and ease of use. For example, a cycler device may include a heater bag receiving section and a lid mounted to cover and uncover the heater bag receiving section, potentially enabling faster heating of a dialysate.
Deka Products Limited Partnership


05/19/16
20160135436 
 Method for inducing artificial ovulation and spawning of fresh-water eels patent thumbnailMethod for inducing artificial ovulation and spawning of fresh-water eels
According to an example, artificial ovulation and spawning of freshwater eels may be induced to promote artificial ovulation without employing intraperitoneal injection, by feeding a feminization-inducing material (e.g., 17β-estradiol) for inducing feminization during a predetermined period into a raising bath in which broodfish are raised and, when an ovulation induction period arrives, adding pituitary extracts of catadromous fish as an artificial ovulation-promoting substance to the bath. Raising water of the raising bath may be prepared by selectively setting fresh water, brackish water and seawater conditions, a feminization-inducing material for inducing complete feminization of broodfish of the freshwater eels is fed to the raising bath, including the raising water under a fresh water condition, and pre-treatment for feminization is performed.
Googol Holdings Co., Ltd


05/05/16
20160122704 
 Method for separation of sporadic cells from body fluids, and  carrying out said method patent thumbnailMethod for separation of sporadic cells from body fluids, and carrying out said method
Method for gentle separation of viable sporadic cells from body fluids such as blood, from malignant effusions, bronchoalveolar lavage fluid, peritoneal lavage fluid and amniotic fluid, based on a filter membrane which is in an intimate contact with an absorbent material. Using the present method it is possible to isolate for example circulating and disseminated tumor cells, endometrial cells and circulating trophoblast cells, allowing subsequent detection, quantification, characterization and especially culturing of said cells.
Metacell, S.r.o.


05/05/16
20160120829 
 Hemodialysis and peritoneal dialysis solutions comprising one or more creatine compounds patent thumbnailHemodialysis and peritoneal dialysis solutions comprising one or more creatine compounds
The present invention provides a hemodialysis solution or concentrate thereof including creatine compound(s), the use of creatine compound(s) for preparing a dialysis solution or concentrate thereof, a method for preparing creatine-containing dialysis solutions and concentrates, and a method for treating patients with dialysis dependent renal failure with creatine compounds to provide a variety of significant health benefits and improvement of life quality parameters for dialysis patients. This is achieve by supporting and improving the physiological functions of organs and cells via creatine compounds delivery to the patients, and by protecting organs and cells of the patients from deleterious effects of a variety of endogenous or exogenous cellular stressors that are linked to the disease state or to the clinical treatment modalities.
Crearene Ltd.


04/28/16
20160114040 
 Derivatized hyperbranched polyglycerols patent thumbnailDerivatized hyperbranched polyglycerols
Herein are provided derivatized hyperbranched polyglycerols (“dhpgs”). The dhpg comprises a core comprising a hyperbranched polyglycerol derivatized with c1c20 alkyl chains and a shell comprising at least one hydrophilic substituent bound to hydroxyl groups of the core, wherein the hyperbranched polyglycerol comprises from about 1 to about 200 moles of the at least one hydrophilic substituent.
Centre For Drug Research And Development


04/21/16
20160108399 
 Modulation of hsp47 expression patent thumbnailModulation of hsp47 expression
Provided herein are compositions, methods and kits for modulating expression of target genes, particularly heat shock protein 47 (hsp47). The compositions, methods and kits may include nucleic acid molecules (for example, short interfering nucleic acid (sina), short interfering rna (sirna), double-stranded rna (dsrna), micro-rna (mirna) or short hairpin rna (shrna)) that modulate a gene encoding hsp47, for example, the gene encoding human hsp47.

04/21/16
20160106904 

Hybrid blood and peritoneal dialysis treatment systems and methods


A method for a hybrid blood and peritoneal dialysis (“pd”) machine comprising: (i) determining whether a previous treatment left a last fill of dialysate in a patient's peritoneum; (ii) if a next treatment is a pd treatment, and if the previous treatment did not leave the last fill of dialysate, causing a pd treatment in which a first cycle is a fill cycle to be initiated; (iii) if the next treatment is a pd treatment, and if the previous treatment did leave the last fill of dialysate, causing a pd treatment in which a first cycle is a last fill drain cycle to be initiated; and (iv) if the next treatment is a blood treatment and if the previous treatment did leave the last fill of dialysate, causing a blood treatment including a last fill drain cycle to be initiated.. .

04/14/16
20160101278 

Medical treatment system and methods using a plurality of fluid lines


Improvements in fluid volume measurement systems are disclosed for a pneumatically actuated diaphragm pump in general, and a peritoneal dialysis cycler using a pump cassette in particular. Pump fluid volume measurements are based on pressure measurements in a pump control chamber and a reference chamber in a two-chamber model, with different sections of the apparatus being modeled using a combination of adiabatic, isothermal and polytropic processes.

04/14/16
20160101228 

Method and system providing more accurate fluid temperature monitoring with selectable fluid input and output arragements for body cavity treatments


Arrangements of components for use in support of a hyperthermic intraperitoneal chemotherapy (hipec) system which conveys fluids from a system to a patient and back to the system in a complete circuit. The described arrangements provide multiple means of rapidly configuring the number of input lines and output lines into and out of the patient.

04/14/16
20160101227 

Medical treatment system and methods using a plurality of fluid lines


Improvements in fluid volume measurement systems are disclosed for a pneumatically actuated diaphragm pump in general, and a peritoneal dialysis cycler using a pump cassette in particular. Pump fluid volume measurements are based on pressure measurements in a pump control chamber and a reference chamber in a two-chamber model, with different sections of the apparatus being modeled using a combination of adiabatic, isothermal and polytropic processes.

03/31/16
20160089485 

Universal portable machine for online hemodiafiltration using regenerated dialysate


Manifolds suitable for use in hemodialysis, hemofiltration, hemodiafiltration, and peritoneal dialysis are provided. One or more of the manifolds can include a manifold body and an external tube.
Fresenius Medical Care Holdings, Inc.


03/24/16
20160083456 

Composition and methods based on neutralizing antibodies delivered intranasally for enhanced therapeutic efficacy


The present invention provides methods for treatment or prophylaxis of viruses, particularly influenza virus, by administration of agents, particularly neutralizing antibodies or active fragments thereof, directly to the respiratory tract, including by intranasal or inhalation administration. The invention provides compositions suitable for intranasal or inhalation treatment and administration.
Contrafect Corporation


03/24/16
20160083448 

Site 2 insulin analogues


An insulin analogue contains one or more modifications at a distinct protein surface comprising one or more of the residues at position b13, b17, a12, a13, and/or a17. Formulations of the above analogues at successive strengths u-100 to u-1000 in soluble solutions a at least ph value in the range 6.8-8.0 either in the presence of zinc ions at a molar ratio of 2.2-10 zinc ions per six insulin analogue monomers or in the presence of fewer than 1 zinc ions per six insulin analogue monomers.
Case Western Reserve University


03/24/16
20160082173 

Medical treatment system and methods using a plurality of fluid lines


A medical treatment system, such as peritoneal dialysis system, may include control and other features to enhance patient comfort and ease of use. For example, a peritoneal dialysis system may include a control system that can adjust the volume of fluid infused into the peritoneal cavity to prevent the intraperitoneal fluid volume from exceeding a pre-determined amount.
Deka Products Limited Partnership


03/24/16
20160082138 

Ultraviolet disinfection unit


An ultraviolet (uv) disinfection unit for disinfecting catheter line connections is provided. The unit can be used to disinfect solution set and transfer set catheters used for peritoneal dialysis.

03/17/16
20160074638 

Ventriculoperitoneal shunt with pressure responsive element


A ventriculoperitoneal shunt includes a proximal catheter, a distal catheter, a shunt valve operably coupling the proximal catheter to the distal catheter, and a contrast container containing contrast material configured to change acoustic impedance proportionally to a change in pressure applied to the contrast container.. .
The Johns Hopkins University


03/17/16
20160074463 

Use of the pat nonapeptide in the treatment and prevention of neurodegenerative diseases


A pat nonapeptide of formula eaksqggsd can be used to treat or prevent neurodegenerative diseases such as alzheimer's disease, parkinson's disease, huntington's disease and amyotrophic lateral sclerosis. Pharmaceutical compositions containing the pat nonapeptide can be formulated for administration by parenteral route, including the subcutaneous, intraperitoneal, intravenous or intranasal routes..
Orphit


03/10/16
20160067399 

Drain and fill logic for automated peritoneal dialysis


A system for performing a peritoneal dialysis therapy includes at least one dialysis fluid pump, and a control unit operable with the at least one dialysis fluid pump to perform a plurality of peritoneal dialysis cycles, the cycles including a fill phase, a dwell phase and a drain phase. The control unit configured to (i) store a previously entered continuous cycling peritoneal dialysis (“ccpd”) therapy having a total prescribed fresh dialysate fill volume delivered over n cycles, the cycles performed over a total therapy duration, and (ii) automatically convert the ccpd therapy into a tidal peritoneal dialysis therapy having n+1 cycles, less a number of cycles already completed during the ccpd therapy, using the total prescribed fresh dialysis fill volume, and maintaining the total therapy duration..
Baxter Healthcare S.a.


03/10/16
20160067280 

Intradialytic administration of sodium thiosulfate


The invention provides a source of sodium thiosulfate via the dialysate used to cleanse the bool of toxic and metabolic waste in the patients undergoing hemodialysis, peritoneal dialysis, or gastro-intestinal dialysis for treatment of end-stage or near end-stage chronic renal disease. In the method of the invention, dialysis solution components contain therapeutic amounts of sodium thiosulfate, which when fully reconstituted for use as a single solution, deliver 20-130 mg/dl of dialysate..

03/03/16
20160060915 

Door latch


A rotatable door latch for a door hingedly attached the housing of a device, which in some embodiments may be a medical device for handling fluids, such as a peritoneal dialysis cycler with pump cassette. In an embodiment, the door is configured to close over an installed cassette against a front panel of the housing, the door latch configured to capture the head of a post mounted to the housing.
Deka Products Limited Partnership


03/03/16
20160058854 

Cancer vaccines and vaccination methods


Compositions of multipeptide vaccines comprising at least seven tumor associated antigens, compositions of antigen presenting cell (e.g., dendritic cell) based vaccines presenting epitopes from at least seven tumor associated antigens, and methods of making same, are provided herein. Also, disclosed are methods for treating gynecological and peritoneal cancers using such vaccines..
Immunocellular Therapeutics, Ltd


02/18/16
20160045513 

Isoxazole compound for the treatment of cancer


The use of 5-(2,4-dihydroxy-5-isopropyl-phenyl)-4-(4-morpholin-4-ylmethyl-phenyl)-isoxazole-3-carboxylic acid ethylamide or a tautomer thereof or a pharmaceutically acceptable salt or a hydrate or a solvate for the treatment of cancer of the bladder, the colon, the liver, the lung, the breast, the vagina, the ovaries, the pancreas, the kidney, the stomach, the gastrointestinal tract, the prostate, the head and neck, the peritoneal cavity, the thyroid, the bone, the brain, the central nervous system and/or the blood and/or for the treatment of myelodysplastic syndrome, systemic mastocytosis, von hippel-lindau syndrome, multicentric castleman disease and/or psioriasis.. .
Novartis Ag


02/11/16
20160038522 

Method for preparing a medical solution for the manufacture of a medicament for peritoneal dialysis


Method for preparing a medical solution, comprising the steps of a) providing a solution comprising one or more acetylated or deacetylated amino sugar/sugars in at least one compartment of a container at a ph from 2.5 to 5.0, and b) terminal sterilisation of said at least one compartment and the contents therein, is disclosed, as well as a solution used for preparing the medical solution, a container containing said solution, and use of said solution for the manufacture of a medicament for peritoneal dialysis.. .
Fresenius Medical Care Deutschland Gmbh


02/11/16
20160038519 

Administration of karenitecin for the treatment of advanced ovarian cancer, including chemotherapy-resistant and/or the mucinous adenocarcinoma sub-types


The present invention discloses and claims methods and compositions for the treatment of platinum and/or taxane cancer treating agent-resistant/-refractory sub-populations and/or the mucinous adenocarcinoma sub-type of ovarian cancer subjects with the silicon-containing highly lipophilic camptothecin derivative (hlcd), karenitecin (also known as bnp1350; cositecan; 7-[(2′-trimethylsilyl)ethyl]-20(s) camptothecin). The administration of karenitecin by intravenous (i.v.) and/or oral methodologies are also disclosed and claimed.
Bionumerik Pharmaceuticals, Inc.


01/28/16
20160025725 

Method for identifying a bacterial infection


Method for identifying a bacterial infection the present application concerns a method for identifying the nature of a bacterial infection from a peritoneal sample, in particular, whether it is a gram-negative or gram-positive infection, based upon the determination of one or more cellular and/or humoral markers in a sample.. .
University College Cardiff Consultants Limited


01/28/16
20160022835 

Targeted polymeric inflammation-resolving nanoparticles


Sub-100 micron multimodal nanoparticles have four main components: 1) a target element (peptides, lipids, antibodies, small molecules, etc.) that can selectively bind to cells, tissues, or organs of the body; 2) a diagnostic agent such as a fluorophore or nmr contrast agent that allows visualization of nanoparticles at the site of delivery and/or a therapeutic or prophylactic agent; 3) an outside “stealth” layer that allows the particles to evade recognition by immune system components and increase particle circulation half-life; and 4) a biodegradable polymeric material, forming an inner core which can carry therapeutics and release the payloads at a sustained rate after systemic, intraperitoneal, or mucosal administration. These particles possess excellent stability, high loading efficiency, multiple agent encapsulation, targeting and imaging.
The Trustees Of Columbia University


01/28/16
20160022483 

Method and spinal cooling


A method for exchanging heat with a patient's spinal column incident to spinal surgery or to relieve a patient for a hypoxia condition of the spine. A closed loop heat exchange catheter is percutaneously advanced into the retroperitoneal space of the patient or into the vasculature, and then heat exchange fluid is circulated through the catheter to cool the spinal column..
Zoll Circulation, Inc.


01/14/16
20160008529 

Peritoneal dialysis system and method


A peritoneal dialysis machine that includes a base, a boiling vessel, a condenser, a fluid storage vessel, a sterilizing uv lamp, a fluid mixer, a dialysate cassette, a boiling vessel demineralizing system, and an optional fluid storage vessel rinsing system. The peritoneal dialysis machine automatically generates a predetermined volume of distilled water each day.

01/07/16
20160002587 

System for producing tissue-engineered material


A system for producing a tissue-engineered material includes a hollow member and a mechanical stimulating unit. The hollow member is adapted to be implanted in a peritoneal cavity, and is to be positioned in the peritoneal cavity in a manner that a part of the hollow member contacts an inner wall surface of the peritoneal cavity for enabling formation of a biological tissue that encapsulates the hollow member.
National Cheng Kung University


01/07/16
20160002215 

Pyridine derivatives as rearranged during transfection (ret) kinase inhibitors


This invention relates to novel compounds which are inhibitors of the rearranged during transfection (ret) kinase, to pharmaceutical compositions containing them, to processes for their preparation, and to their use in therapy, alone or in combination, for the normalization of gastrointestinal sensitivity, motility and/or secretion and/or abdominal disorders or diseases and/or treatment related to diseases related to ret dysfunction or where modulation of ret activity may have therapeutic benefit including but not limited to all classifications of irritable bowel syndrome (ibs) including diarrhea-predominant, constipation-predominant or alternating stool pattern, functional bloating, functional constipation, functional diarrhea, unspecified functional bowel disorder, functional abdominal pain syndrome, chronic idiopathic constipation, functional esophageal disorders, functional gastroduodenal disorders, functional anorectal pain, inflammatory bowel disease, proliferative diseases such as non-small cell lung cancer, hepatocellular carcinoma, colorectal cancer, medullary thyroid cancer, follicular thyroid cancer, anaplastic thyroid cancer, papillary thyroid cancer, brain tumors, peritoneal cavity cancer, solid tumors, other lung cancer, head and neck cancer, gliomas, neuroblastomas, von hippel-lindau syndrome and kidney tumors, breast cancer, fallopian tube cancer, ovarian cancer, transitional cell cancer, prostate cancer, cancer of the esophagus and gastroesophageal junction, biliary cancer, adenocarcinoma, and any malignancy with increased ret kinase activity.. .
Glaxosmithkline Intellectual Property Development Limited


01/07/16
20160000984 

Dialysis implant and methods of use


A device and methods for treating renal failure are disclosed. One embodiment of the device is an implantable peritoneal dialysis device.
Sequana Medical Ag


12/24/15
20150366952 

Methods for reducing fibrosis induced by peritoneal dialysis


The disclosure relates to a method of preventing, inhibiting, or reducing fibrosis, the incidence of fibrosis or the progression of fibrosis associated with peritoneal dialysis, during or after peritoneal is administered. More specifically, the methods relates to using intraperitoneal administration of activated protein c (apc) possessing cytoprotective or anti-inflammatory activity, to reduce the incidence or progression of fibrosis associated with peritoneal dialysis.
Saint Louis University


12/17/15
20150359957 

Axially split foam peritoneal dialysis catheter design with functional coatings


The present disclosure provides a dialysis device for peritoneal dialysis. The device comprises a proximal tubular portion comprising a plurality of proximal lumens and a distal tubular portion comprising a plurality of independent tubes.
Cook Medical Technologies Llc


12/10/15
20150352348 

Transfer catheter for ultraviolet disinfection


Disclosed herein are devices and methods related to uv disinfection of a transfer catheter during peritoneal dialysis. The transfer catheter comprises a first and second end, the second end comprising a transfer valve.

12/10/15
20150352271 

Medical device


A medical device, preferably for peritoneal dialysis, is described which comprises a film tube.. .

11/19/15
20150327973 

Auto-graft bio-synthetic mesh for ventral and parastomal hernia repair and attachment as well as a suture clip


An auto-graft bio-synthetic mesh and a method of application for wound closure is described. The mesh is utilized for wound closure wherein an abdominal incision is effected through the peritoneum and the rectus abdominal sheath of the rectus muscle such as when repairing ventral or paracoslostomy hernias.

11/12/15
20150322229 

Antimicrobial housing and cover for a medical device


A method for immobilizing dyes and antimicrobial agents on a polymeric cover or housing for a medical device is disclosed and described. The surface may be that of a catheter, a connector, a drug vial spike, a bag spike, a prosthetic device, an endoscope, a surface of an infusion pump, a key pad, a touch screen or a handle.
Baxter Healthcare S.a.


10/29/15
20150306035 

Pharmaceutical composition containing conventional liposomes and prolonged-circulation liposomes for the treatment of visceral leishmaniasis


The present invention relates to a pharmaceutical composition for treating visceral leishmaniasis, characterized in that it comprises the association of conventional liposomes and prolonged-circulation liposomes with a leishmanicidal-drug delivery system. Said composition may be used in the preparation of a medicinal product for treating leishmaniasis and may be administered intramuscularly, subcutaneously, intraperitoneally or intravenously.
FundaÇao De Amparo A Pesquisa Do Estado De Minas Gerais- Fapemig


10/22/15
20150297815 

Method of adsorption of ions from a dialysis fluid


A method of adsorption of potassium ions from a peritoneal dialysis fluid, which has been removed from the peritoneal cavity of a patient performing peritoneal dialysis for subsequent recirculation and introduction into the peritoneal cavity of the patient. The peritoneal dialysis fluid is passed through a potassium adsorbent, such as a zeolite, which has been pre-equilibrated with an equilibration fluid comprising na+, ca2+, mg2+, cl−, lactate, in substantially the same concentration as in the peritoneal dialysis fluid and which equilibration fluid lacks k+.
Triomed Ab


10/08/15
20150282836 

Laparoscopic tool with obturator


A laparoscopic device with obturator. The device facilitates extraction of specimens from a female subject's abdominal cavity through the subject's vagina by also facilitating the suturing of a mesh to the anterior and posterior walls of the subject's vagina.

10/01/15
20150272561 

Tissue debris and blood collection device and methods of use thereof


Protective barrier for laparoscopy is provided and comprises bag with closed bottom, wall(s), and open end. Bag may comprise drawstring and/or optional flexible stay(s), in internal channel around periphery of open end of bag.
Laparoscopic Innovations Llc


09/17/15
20150258313 

Tunneling guidewire


A medical device tunneling system, and a method of using the same, to subcutaneously route trocars, also commonly referred to as tunnelers, or introducers, having a cannula, stylet, and a guidewire stylet, inside a patient during a surgical procedure, such as a ventriculoperitoneal hydrocephalus shunt implantation, from a proximal entry point to a distal end point, in order to subcutaneously route and implant a medical device, such as shunt tubing, in a patient.. .
Arkis Biosciences


09/17/15
20150258134 

Chondroitin for use in medicine


Chondroitin, a metabolic intermediate of chondroitin sulphate biosynthesis in mammals and other living organisms, possesses biological properties different from those of chondroitin sulphate, and can be advantageously used for applications in the pharmaceutical, nutraceutical, cosmeceutical and medical device fields. Chondroitin has biostimulating, anti-inflammatory and anti-microbial activity and can be used in the treatment of osteoarthritis, eye disorders, interstitial cystitis, lung disorders, inflammatory disorders in general, oncological disorders, peritoneal dialysis, tissue biorevitalisation and wound repair, as a skin filler, and as bioresorbable scaffolds..
Altergon S.a.


09/10/15
20150250928 

Reducing post-operative adhesion formation with intraperitoneal glutamine


Intraperitoneal administration of glutamine to reduce adhesions in the peritoneum of a patient.. .
Ade Therapeutics Inc.


09/10/15
20150250819 

Peritoneal dialysis fluid


The present invention is a sterile peritoneal dialysis fluid, including an acidic first liquid containing 60.0 to 94.0 g/l of icodextrin and 0 to 2.34 g/l of sodium chloride, and an alkaline second liquid containing an alkaline ph regulator, in which the first liquid after sterilization has a ph of 5.0 to 5.5, the second liquid after sterilization has a ph of 6.5 to 7.5, and a mixture of the first liquid and the second liquid after sterilization has a ph of 6.0 to 7.5. The present invention can provide a peritoneal dialysis fluid containing icodextrin, in which the stability of icodextrin during the heat sterilization and the subsequent storage can be improved to the maximum, and the ph of the peritoneal dialysis fluid is close to the physiological range..
Terumo Kabushiki Kaisha


08/27/15
20150238419 

Partially absorbable fiber-reinforced composites for controlled drug delivery


This invention describes a partially absorbable, fiber-reinforced composite in the form of a ring, or a suture-like thread, with modified terminals for use as a controlled delivery system of at least one bioactive agent, wherein said composite comprising an absorbable fiber construct capable of providing time-dependent mechanical properties of a biostable elastomeric matrix containing an absorbable microparticulate ion-exchanger to modulate the release of the bioactive agent(s) for a desired period(s) of time at a specific biological site; this can be a vaginal canal, peritoneal cavity, scrotum, prostate gland, an ear loop or subcutaneous tissue. Such drug delivery systems can be used for the local administration of at least one bioactive agent, including those used as contraceptive, antimicrobial, anti-inflammatory and/or antiviral agents as well as for cancer treatment..
Poly-med, Inc.




Peritoneal topics: Peritoneal, Peritoneal Dialysis, Peritoneal Cavity, Dialysis System, Intraperitoneal, Abdominal Cavity, Hemodialysis, Anastomosis, Wireless Communication Device, Colorectal, Hydrogen Sulfide, Sulfonamide, Ultraviolet, Ultraviolet Light, Subcutaneous

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