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Peptide patents



      
           
This page is updated frequently with new Peptide-related patent applications. Subscribe to the Peptide RSS feed to automatically get the update: related Peptide RSS feeds. RSS updates for this page: Peptide RSS RSS


Date/App# patent app List of recent Peptide-related patents
02/26/15
20150059022
 Genes controlling plant root growth and development for stress tolerance and  their use patent thumbnailnew patent Genes controlling plant root growth and development for stress tolerance and their use
Microarrays are employed to analyze soybean transcriptome under water stress conditions in different regions of the root at vegetative stage. Drought responsive genes and transcription factors are identified which may be used for enhancing drought tolerance in soybean or other plants through genetic/metabolic engineering.
The Curators Of The University Of Missouri
02/26/15
20150059018
 Methods and compositions for producing drimenol patent thumbnailnew patent Methods and compositions for producing drimenol
The present invention relates to nucleic acids sequences derived from valeriana officinalis and/or persicaria hydropiper and encoding drimenol synthase polypeptides. The present invention also provides the amino acid sequences of the polypeptides.
Keygene N.v.
02/26/15
20150059014
 Polynucleotides and polypeptides in plants patent thumbnailnew patent Polynucleotides and polypeptides in plants
The invention relates to plant transcription factor polypeptides, polynucleotides that encode them, homologs from a variety of plant species, and methods of using the polynucleotides and polypeptides to produce transgenic plants having advantageous properties compared to a reference plant. Sequence information related to these polynucleotides and polypeptides can also be used in bioinformatic search methods and is also disclosed..
Mendel Biotechnology, Inc.
02/26/15
20150057605
 Stable glucagon peptide formulations patent thumbnailnew patent Stable glucagon peptide formulations
There is provided glucagon formulations suitable for preparing coatings on microneedle patches for the transdermal delivery of glucagon. The coated patches may be used for the treatment of low blood sugar in diabetic patients.
Zosano Pharma, Inc.
02/26/15
20150057441
 Sequence-determined dna fragments encoding acetohydroxyacid synthase proteins patent thumbnailnew patent Sequence-determined dna fragments encoding acetohydroxyacid synthase proteins
The present invention provides dna molecules that constitute fragments of the genome of a plant, and polypeptides encoded thereby. The dna molecules are useful for specifying a gene product in cells, either as a promoter or as a protein coding sequence or as an utr or as a 3′ termination sequence, and are also useful in controlling the behavior of a gene in the chromosome, in controlling the expression of a gene or as tools for genetic mapping, recognizing or isolating identical or related dna fragments, or identification of a particular individual organism, or for clustering of a group of organisms with a common trait..
Ceres, Inc.
02/26/15
20150057433
 Preparation of functionalized polypeptides, peptides, and proteins by alkylation of thioether groups patent thumbnailnew patent Preparation of functionalized polypeptides, peptides, and proteins by alkylation of thioether groups
Reagents are disclosed for chemoselective tagging of methionine residues in peptides and polypeptides, subsequent bioorthogonal tag functionalization, and cleavage of the tags when desired to regenerate unmodified samples. This method compliments other peptide tagging strategies and adds capability for tag removal, which may be useful for release of therapeutic peptides from a carrier, or release of tagged protein digests from solid supports..
The Regents Of The University Of California
02/26/15
20150057432
 Methods and compositions for improved f-18 labeling of proteins, peptides and other molecules patent thumbnailnew patent Methods and compositions for improved f-18 labeling of proteins, peptides and other molecules
The present application discloses compositions and methods of synthesis and use of 18f- or 19f-labeled molecules of use in pet, spect and/or mr imaging. Preferably, the 18f or 19f is conjugated to a targeting molecule by formation of a complex with a group iiia metal and binding of the complex to a bifunctional chelating agent, which may then be directly or indirectly attached to the targeting molecule.
Immunomedics, Inc.
02/26/15
20150057430
 Compound, use and method patent thumbnailnew patent Compound, use and method
The present invention relates to the use of an antagonist of kisspeptin in the manufacture of a medicament for the treatment of a condition induced and/or worsened by kisspeptin activity in an individual. The invention also provides certain defined peptide molecules, which may act as an antagonist of kisspeptin, which are of use in treating a condition induced and/or worsened by kisspeptin activity in an individual.
Medical Research Council
02/26/15
20150057340
 Nucleic acid comprising or coding for a histone stem-loop and a poly(a) sequence or a polyadenylation signal for increasing the expression of an encoded therapeutic protein patent thumbnailnew patent Nucleic acid comprising or coding for a histone stem-loop and a poly(a) sequence or a polyadenylation signal for increasing the expression of an encoded therapeutic protein
The present invention relates to a nucleic acid sequence, comprising or coding for a coding region, encoding at least one peptide or protein comprising a therapeutic protein or a fragment, variant or derivative thereof, at least one histone stem-loop and a poly(a) sequence or a polyadenylation signal. Furthermore the present invention provides the use of the nucleic acid for increasing the expression of said encoded peptide or protein, particularly for the use in gene therapy.
Curevac Gmbh
02/26/15
20150057335
 Novel fusion genes identified in lung cancer patent thumbnailnew patent Novel fusion genes identified in lung cancer
[means for solving] a method for detecting a gene fusion serving as a responsible mutation (driver mutation) for cancer, the method comprising the step of detecting any one of an ezr-erbb4 fusion polynucleotide, a kiaa1468-ret fusion polynucleotide, a trim24-a braf fusion polynucleotide, a cd74-nrg1 fusion polynucleotide, and an slc3a2-nrg1 fusion polynucleotide, or a polypeptide encoded thereby, in an isolated sample from a subject with cancer.. .
02/26/15
20150057326
new patent

Method for synthesizing cycloalkanyl[b]indoles, cycloalkanyl[b]benzofurans, cycloalkanyl[b]benzothiophenes, compounds and methods of use


A method of synthesizing cycloalkanyl[b]indoles, as well as related cycloalkanyl[b]benzofurans and cycloalkanyl[b]benzothiophenes is provided. The method is a single, multicomponent reaction that combines (1) an indole, benzofuran, or benzothiopene, (2) an aldehyde, ketone, or ketal, and (3) a diene in the presence of an acid, in particular a ga(iii) or in(iii) salt.
Trustees Of Dartmouth College
02/26/15
20150057283
new patent

Reverse-turn mimetics and method relating thereto


Conformationally constrained compounds that mimic the secondary structure of reverse-turn regions of biologically active peptides and proteins are disclosed. Such reverse-turn mimetic structures have utility over a wide range of fields, including use as diagnostic and therapeutic agents.
Choongwae Pharma Corporation
02/26/15
20150057268
new patent

Composition and neuropeptide s receptor (npsr) antagonists


Neuropeptide s receptor antagonists are provided that bind in functional assays to neuropeptide s receptors; methods are provided for use of these antagonists in treatment of conditions or disease states that are ameliorated by blocking of the neuropeptide s receptor, including substance abuse and substance abuse relapse; and for use of neuropeptide s receptor antagonists in the manufacture of therapeutics and pro-drugs for therapeutics useful in disease states and conditions sensitive to binding of the neuropeptide s receptor.. .
Research Triangle Institute
02/26/15
20150057235
new patent

Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders


The invention provides novel guanylate cyclase-c agonist peptides and their use in the treatment of human diseases including gastrointestinal disorders, inflammation or cancer (e.g., a gastrointestinal cancer). The peptides can be administered either alone or in combination with an inhibitor of cgmp-dependent phosphodiesterase.
Synergy Pharmaceuticals, Inc.
02/26/15
20150057234
new patent

Hydrate of cyclopeptide compound as well as preparation method and use thereof


Disclosed is a hydrate of a compound as shown in formula i. In formula i, r represents h or a cation capable of forming a pharmaceutically acceptable salt.
Shanghai Techwell Biopharmaceutical, Co., Ltd.
02/26/15
20150057230
new patent

Biotin-conjugated hexapeptide-2 derivative and use thereof


The present invention relates to a biotin-conjugated hexapeptide-2 derivative or a pharmaceutically acceptable salt thereof and use thereof. More particularly, the present invention relates to a biotin-conjugated hexapeptide-2 derivative or a pharmaceutically acceptable salt thereof, a preparation method thereof, a composition including the same as an active ingredient, and a method for improving wrinkles and inhibiting skin aging using the same..
Incospharm Corporation
02/26/15
20150057229
new patent

Method of treating bone disorders using tsg-6


A method for inhibiting cartilage degradation comprising administering to a subject a therapeutically effective amount of a polypeptide comprising or consisting of a link_tsg6 polypeptide is disclosed. .
The University Of Manchester
02/26/15
20150057227
new patent

Compositions, devices and methods of use thereof for the treatment of cancers


The use of glp-1 receptor agonists, such as glucagon-like peptide-1 (glp-1) or exenatide, for the treatment of cancer is described. The glp-1 receptor agonists are typically delivered using an implanted osmotic delivery device that provides for continuous delivery of the glp-1 receptor agonist for at least one month.
Intarcia Therapeutics, Inc.
02/26/15
20150057219
new patent

Reversible pegylated drugs


Reversible pegylated drugs are provided by derivatization of free functional groups of the drug selected from amino, hydroxyl, mercapto, phosphate and/or carboxyl with groups sensitive to mild basic conditions such as 9-fluorenylmethoxycarbonyl (fmoc) or 2-sulfo-9-fluorenylmethoxycarbonyl (fms), to which group a peg moiety is attached. In these pegylated drugs, the peg moiety and the drug residue are not linked directly to each other, but rather both residues are linked to different positions of the scaffold fmoc or fms structure that is highly sensitive to bases and is removable under physiological conditions.
Yeda Research And Development Co., Ltd.
02/26/15
20150057217
new patent

Short designed peptides possessing selective actions against bacteria and cancer cells


Or a salt thereof. The invention further relates to use of the peptides as antibacterial agents, or antitumor agents, including the medical use of the peptide in treating infection and/or cancer, as well as their use as preservatives and antibacterial agents in other products, including personal care products such as skin topical treatments, cleansers, mouth washes, toothpastes, shampoo, body lotions and creams etc..
02/26/15
20150057216
new patent

Angiotensins for treatment of fibrosis


The present invention provides, among other things, methods and compositions for treating or preventing fibrotic diseases, disorders or conditions based on angiotensin (1-7) polypeptides, and analogs or derivatives thereof. In some embodiments, compositions and methods for treating or preventing pulmonary fibrosis, pulmonary hypertension, chronic obstructive pulmonary disease (copd), asthma, cystic fibrosis, kidney fibrosis, liver fibrosis, systemic sclerosis, post-surgical adhesions, accelerating wound healing, and reducing or preventing scar formation are provided..
Tarix Pharmaceuticals Ltd.
02/26/15
20150057193
new patent

Endothelial-monocyte activating polypeptide ii (emap-ii), a biomarker for use in diagnosis and treatment of brain injury


A diagnostic tool and method of diagnosing brain injury and brain injury type (traumatic vs. Ischemic) by detecting the level of expression of endothelial monocyte-activating polypeptide ii (emap ii) and comparing to a control.
02/26/15
20150057186
new patent

Phage display using cotranslational translocation of fusion polypeptides


The present invention relates to a filamentous phage display method wherein the polypeptides of interest displayed on the phage particle are cotranslationally translocated across the cytoplasmic membrane of gram-negative bacteria based on the signal recognition particle pathway. This method is particularly suitable for polypeptides, which are known to be difficult to display on phages, and for proteins of cdna libraries and other combinatorial libraries, in particular when derived from very fast folding, stable protein scaffolds.
University Of Zurich
02/26/15
20150057175
new patent

Method for monitoring hiv specific t cell responses


The invention relates to a method and a diagnostic kit for monitoring hiv specific t cell responses and identifying subjects capable of controlling hiv progression or preventing hiv infection altogether. The method is based on the combined use of boosted flow cytometry and toggle peptides and can cover a vastly larger set of effector functions than standard assays.
InstituciÓ Catalana De Recerca I Estudis AvanÇats
02/26/15
20150057162
new patent

Peptide arrays


A method is disclosed for identifying a member of a peptide library that interacts with a target molecule in situ, the method including expressing immobilised nucleic acid molecules to produce the peptide library in a way that each member of the peptide library is immobilised on the nucleic acid molecule from which it was expressed; contacting the immobilised peptide library with the target molecule; and detecting an interaction between at least one member of the peptide library and the target molecule. The method further comprises sequencing the plurality of nucleic acid molecules in situ on the solid support, such that the at least one member of the peptide library that interacts with the target molecule can be immediately identified, at least by the sequence of the nucleic acid molecule from which it was expressed, without requiring additional or secondary analysis or characterising procedures in order to identify the useful members of the library.
Isogenica Ltd.
02/26/15
20150056700
new patent

Bone morphogenic protein binding peptide


A cyclized peptide designated bmp binding peptide (bbp) is a synthetic peptide that avidly binds rhbmp-2. Bbp increases the overall osteogenic activity of rhbmp-2, increases the rate at which rhbmp-2 induces bone formation, and bbp induces calcification alone.
United States Government Represented By The Department Of Veterans Affairs
02/26/15
20150056680
new patent

Methods for generating stably linked complexes composed of homodimers, homotetramers or dimers of dimers and uses


The present invention concerns methods and compositions for stably tethered structures of defined compositions, which may have multiple functionalities and/or binding specificities. Particular embodiments concern homodimers comprising monomers that contain a dimerization and docking domain attached to a precursor.
Ibc Pharmaceuticals, Inc.
02/26/15
20150056668
new patent

Synthesis of prazole compounds


The present disclosure relates to non-naturally occurring monooxygenase polypeptides useful for preparing prazole compounds, polynucleotides encoding the polypeptides, and methods of using the polypeptides.. .
Codexis, Inc.
02/26/15
20150056656
new patent

Method for reduction of 1->2 reading frame shifts


Herein is reported a method for the recombinant production of a polypeptide, which comprises the dipeptide ar, characterized in that the method comprises the recovering of the polypeptide from the cells or the cultivation medium of a cultivation of a cell comprising a nucleic acid encoding the polypeptide and thereby producing the polypeptide, whereby the dipeptide ar comprised in the polypeptide is encoded by the oligonucleotide gca cgt, or the oligonucleotide gcg cgt, or the oligonucleotide gcc cgt.. .
Hoffmann-la Roche Inc.
02/26/15
20150056655
new patent

Expression constructs and methods for expressing polypeptides in eukaryotic cells


The invention relates to an expression construct for the expression of polypeptides in host cells using alternative splicing. The expression construct can be used for the expression of polypeptides such as antibodies, antibody fragments and bispecific antibodies by expressing the gene products required for protein expression at the ratio leading to the highest titres or the best product quality profile..
Glenmark Pharmaceuticals S.a.
02/26/15
20150056653
new patent

Protein production method


Provided herein are methods of producing a heterologous polypeptide and compositions comprising same.. .
Georgia State University Research Foundation, Inc.
02/26/15
20150056615
new patent

Isolation of factors that associate directly or indirectly with non-coding rnas


Methods and assays are provided for isolating factors including polypeptides, ribonucleic acids (rnas) and polypeptide complexes that are associated with a target nucleic acid sequence. The target nucleic acid sequence may be comprised within chromatin.
The General Hospital Corporation
02/26/15
20150056460
new patent

Protective natural gel system


The present invention relates to a protein/peptide composition for protection of surfaces comprising an aqueous solution of at least two components, the first component (a) being a water-soluble protein or a mixture of water-soluble proteins having an average molecular weight mw of at least 30000, and being capable of forming a gel, and the second component (b) being a water-soluble peptide or a mixture of water-soluble peptides mixture having an average molecular weight of 200-10000, and being capable of inhibiting gel formation in said composition. The present invention further relates to a method for preparing such a composition, the use of the composition for protecting a surface, a method for protecting a substrate surface using the composition, and to a substrate surface coated with the composition..
Professor Sigge & Martin Ab
02/26/15
20150056301
new patent

Peptides and peptidomimetics in combination uses and treatments for cancer patient subpopulations


This invention provides compounds including peptides and peptidomimetics that can be used to treat cell proliferative disorders, such as those associated with benign and malignant tumor cells. While the invention is not limited to any particular mechanism, the compounds of the invention appear to function at least in part by inhibiting g2 cell cycle checkpoint.
Canbas Co., Ltd.
02/26/15
20150056295
new patent

Cellular extracts


The invention describes methods and agents for improving cosmetic appearance, for promoting, improving or restoring health of cells and tissues, preferably skin, and more preferably, for restoring aged or damaged skin to a healthy appearance. The agents include compositions of cells, eggs, cell extracts, egg extracts, and extract components such as purified nucleic acids, polypeptides, lipids, carbohydrates or other natural products..
Regenics As
02/26/15
20150056263
new patent

Implantable meshes for controlling the movement of fluids


Meshes for use to control the movement of bodily fluids, such as blood, are described herein. The mesh can be partially or completely biodegradable or non-biodegradable.
Arch Biosurgery, Inc.
02/26/15
20150056250
new patent

Adjuvant formulations and methods


The present invention is directed to methods for administering antigenic material to a patient as a vaccine against an infection comprising providing both an antigenic material specific to the desired immunological response desired plus an adjuvant comprised of a peptide of a sequence derived from the sequence of pneumococcal surface adhesin a protein (psaa). Preferably the peptide comprises a sequences derived from one or more sequences of psaa that contain the epitope regions or contiguous amino acids of seq id nos 1 or 2.
02/26/15
20150056246
new patent

Subunit vaccine delivery platform for robust humoral and cellular immune responses


The present invention relates to a probiotic cell transformed with a construct suitable to overexpress and display on the surface of the probiotic cell a fusion protein comprising at least a portion of a transport protein coupled to at least a portion of one or more antigenic proteins or peptides. Probiotic-derived vesicles displaying this fusion protein as well as methods of inducing an immune response using the probiotic cells or vesicles are also disclosed..
Cornell University
02/26/15
20150056243
new patent

Multicomponent or monocomponent vaccine to be used against chagas disease, pharmaceutical compositions containing them, procedure for the obtention of immunogen of said vaccines, and nucleic acid used in said procedure


A vaccine against the chagas disease, capable of stimulating the immune response against the trans-sialidase virulence factor of the trypanosoma cruzi parasite, which is a multicomponent vaccine comprising: (a) an immunogenic portion formed by one or more recombinant or synthetic polypeptides or fractions of thereof and (b) one or more polynucleotides including the regions codifying one or more immunogenic polypeptides, or a monocomponent vaccine comprising at least one component selected among an immunogenic portion formed by one or more recombinant or synthetic polypeptides or fractions of them and a group of polynucleotides including the regions codifying one or more immunogenic polypeptides derived from trypanosoma cruzi and pharmaceutical compositions containing said multicomponent and monocomponent vaccines, the procedures for obtaining the immunogen portion of said vaccines and the nucleic acid used in the procedure.. .
02/26/15
20150056238
new patent

Isolated polypeptide of the toxin a and toxin b proteins of c. difficile and uses thereof


This present invention provides c-tab.g5 and c-tab.g5.1 isolated polypeptides comprising the receptor binding domains of c. Difficile toxin a and toxin b as set forth in the amino acid sequences of seq id no: 2 and seq id no: 4.
Valneva Austria Gmbh
02/26/15
20150056234
new patent

Hpv epitopes targeted by t cells infiltrating cervical malignancies for use in vaccines


The present invention relates to novel cd4+ and cd8+ t cell epitopes that are specific for hpv-specific e6 and e7 oncoproteins, to peptides comprising these novel t cell epitopes, and to (vaccine) compositions comprising these peptides for use in methods for the prevention and/or treatment of hpv related diseases. Preferred epitopes are recognized by a t cell that infiltrates a cervical neoplastic lesion or by a t cell from a draining lymph node, and are presented by an hla-dq or hla-dp molecule, or an hla-b..
Academisch Ziekenhuis Leiden H.o.d.n. Lumc
02/26/15
20150056233
new patent

Influenza hemagglutinin proteins and methods of use thereof


In some embodiments the present invention provides influenza hemagglutinin (“ha”) polypeptides, proteins, and protein complexes that comprise a stalk domain that is engineered to facilitate maintenance of its native trimeric conformation, even if the head domain of the ha protein is removed or disrupted. In some embodiments, the present invention provides compositions comprising such polypeptides, proteins, and protein complexes, and methods of use of such proteins and compositions, for example as vaccine immunogens..
02/26/15
20150056231
new patent

Recombinant papaya mosaic virus coat proteins and uses thereof in influenza vaccines


Recombinant papaya mosaic virus (papmv) coat proteins comprising one or more antigenic peptides derived from an influenza virus antigen, such as from the m2e peptide, fused at a position within a predicted random coil within 13 amino acids of the n-terminus of the coat protein, uses thereof to prepare virus-like particles (vlps), and uses of the vlps in influenza vaccines.. .
Folia Biotech Inc.
02/26/15
20150056229
new patent

Dna sequence, and recombinant preparation of the grass pollen allergen lol p 4


The present invention relates to the provision of a dna sequence of the major grass pollen allergen lol p 4. The invention also encompasses fragments, new combinations of partial sequences and point mutants having a hypoallergenic action.
Merck Patent Gmbh
02/26/15
20150056223
new patent

Pharmaceutical composition for the prevention or treatment of non-alcoholic fatty liver disease


The present invention relates to a pharmaceutical composition for the prevention and treatment of non-alcoholic fatty liver disease (nafld), including a conjugate prepared by covalently linking an insulinotropic peptide, a non-peptidyl polymer and an immunoglobulin fc region. The composition of the present invention maintains the in-vivo activity of the peptide at a relatively high level, and remarkably increases the blood half-life, thereby preventing triglyceride accumulation which is a typical feature of non-alcoholic fatty liver disease.
Hanmi Science Co., Ltd
02/26/15
20150056209
new patent

Peptide mimotopes to oxidation specific epitopes


Provided herein are peptide mimotopes that are useful for generating antibodies and in the preparation of vaccines and diagnostics for treating and diagnosing coronary artery disease.. .
Medizinsche Universitat Wien
02/26/15
20150056208
new patent

Novel antibodies


Autoimmune reactions to certain epitopes of self antigens most likely contribute to the development of rheumatoid arthritis. Often these epitopes are citrullinated.
Vilara Ab
02/26/15
20150056200
new patent

Methods for increasing adiponectin


In certain aspects, the present invention provides compositions and methods for increasing adiponectin in a patient in need thereof by administering an antagonist of an actriib signaling pathway. Examples of such antagonists include actriib polypeptides, anti-actriib antibodies, anti-activin a and/or b antibodies, anti-myostatin antibodies, anti-gdf3 antibodies, and anti-bmp7 antibodies.
Acceleron Pharma, Inc.
02/26/15
20150056199
new patent

Tgf-beta receptor type ii variants and uses thereof


In certain aspects, the present disclosure relates to polypeptides comprising a truncated, ligand-binding portion of the extracellular domain of tβrii polypeptide useful to selectively antagonize a tβrii ligand. The disclosure further provides compositions and methods for use in treating or preventing tgfβ associated disorders..
Acceleron Pharma, Inc.
02/26/15
20150056198
new patent

Aberrant cell-restricted immunoglobulins provided with a toxic moiety


Described are immunoglobulins provided with a toxic moiety, comprising at least an immunoglobulin variable region that specifically binds to an mhc-peptide complex preferentially associated with aberrant cells. These immunoglobulins provided with a toxic moiety are preferably used in selectively modulating biological processes.
Apo-t B.v.
02/26/15
20150056197
new patent

Vaccines against hpv


The present invention relates to therapeutic compounds, such as vaccines against human papillomavirus (hpv) and in particular to dna vaccines against hpv16 or hpv18. The invention further relates to protein construct encoding homodimeric peptides, which peptides may be released from a dna vaccine or used separately.
Vaccibody As
02/26/15
20150056193
new patent

Egfr and ros1 kinase in cancer


The present disclosure provides methods of that include detecting in a biological sample from a patient having or suspected of having cancer the presence of a polypeptide having ros1 kinase activity or a polynucleotide encoding the same and detecting in the biological sample the presence of a mutant egfr polypeptide or a polynucleotide encoding the same. In some aspects, the disclosure provides methods of treating a patient for cancer that include determining that a biological sample from a tumor in the patient includes a polypeptide having ros1 kinase activity or a polynucleotide encoding the same and a mutant egfr polypeptide or a polynucleotide encoding the same and administering to the patient a therapeutically effective amount of a ros1 inhibitor and an egfr inhibitor, thereby treating the patient for cancer..
Cell Signaling Technology, Inc.
02/26/15
20150056167
new patent

Peptides, derivatives and analogs thereof, and methods of using same


Human proislet peptides (hip) and hip analogs and derivatives thereof, derived from or homologous in sequence to the human reg3a protein, chromosome 2p12, are able to induce islet neogenesis from endogenous pancreatic progenitor cells. Human proislet peptides are used either alone or in combination with other pharmaceuticals in the treatment of type 1 and type 2 diabetes and other pathologies related to aberrant glucose, carbohydrate, andor lipid metabolism, insulin resistance, overweight, obesity, polycystic ovarian syndrome, eating disorders and the metabolic syndrome..
Curedm Group Holdings, Llc
02/26/15
20150056163
new patent

Leukotoxin e/d as a new anti-inflammatory agent and microbicide


The present invention relates to methods for preventing or treating human immunodeficiency virus (hiv) infection, inflammatory conditions, and graft-versus-host-disease (gvhd) in a subject. Therapeutic compositions of the present invention comprise leukocidin e (luke) and/or d proteins or polypeptides.
New York University
02/26/15
20150056162
new patent

Therapeutic il-13 polypeptides


Variant il-13 polypeptides are provided, which are engineered to have one or more of the following properties: (a) altered affinity for il-13rα2, relative to the native human il-13 protein; (b) altered affinity for il-13rα1 relative to the native human il-13 protein; (c) a disruption in the binding site for il-4rα relative to the native human il-13 protein.. .
The Board Of Trustees Of The Leland Stanford Junior University
02/26/15
20150056159
new patent

The igm and ige heavy chain domain 2 as covalently linked homodimerization modules for the generation of fusion proteins with dual specificity


The present invention provides a polypeptides comprising a heavy chain domain 2 (hd2) from igm or ige and at least one pharmaceutically active moiety, complexes thereof and their use for therapy and prophylaxis.. .
Universit T Stuttgart
02/26/15
20150056154
new patent

Hair conditioning composition for permanent and semi-permanent hair coloration applications


The disclosure concerns a hair conditioning composition for permanent and semi-permanent hair color applications wherein the hair conditioning composition comprises a solvent; a water-soluble, oligo-peptide from a natural proteinous raw-material source containing sulfur; alkaline or alkaline earth metal ions; a multidentate ligand or chelating agent and optionally a redox-active inorganic or organic component.. .
Otc Gmbh
02/26/15
20150056137
new patent

Caspase-triggered nano-aggregation probes and methods of use


Provided is an activatable probe that undergoes intramolecular cyclization and subsequent aggregation in apoptotic tumor cells upon peptidase-initiated, and most advantageously caspase-3, activation. These caspase-sensitive nano-aggregation probes (c-snafs) are generally biocompatible, possess nir spectral properties or may serve as pet or mri imaging agents, and have a mechanism of target-mediated nanostructure self-assembly amenable to in vivo use.
The Board Of Trustees Of The Leland Stanford Junior University
02/26/15
20150056133
new patent

Cx3cr1-targeting imaging agents and their use in the diagnosis and treatment of disease


The present invention relates to cx3cr1-targeting imaging agents and their use in treatment and diagnosis of diseases. Single domain cx3cr1-targeting polypeptides linked to detection labels and their use in in vivo imaging of atherosclerotic plaques are described.


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This listing is a sample listing of patent applications related to Peptide for is only meant as a recent sample of applications filed, not a comprehensive history. There may be associated servicemarks and trademarks related to these patents. Please check with patent attorney if you need further assistance or plan to use for business purposes. This patent data is also published to the public by the USPTO and available for free on their website. Note that there may be alternative spellings for Peptide with additional patents listed. Browse our RSS directory or Search for other possible listings.
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