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Peptide

Peptide-related patent applications - as published by the U.S. Patent and Trademark Office (USPTO).


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Genetically encoded calcium indicators and methods of use
Howard Hughes Medical Institute
October 12, 2017 - N°20170292943

Genetically encoded calcium indicator (geci) polypeptides and the nucleic acid molecules encoding such polypeptides are provided. In addition, methods of using such nucleic acids and polypeptides in methods of screening for agonists or antagonists of g-protein coupled receptor (gpcr) or ion channels and methods of monitoring neural activity also are provided.
Novel methods for enzyme mediated polypeptide conjugation
Hoffmann-la Roche Inc.
October 12, 2017 - N°20170292166

Herein is reported a method for producing an enzymatic conjugation product of two polypeptides comprising incubating of a first polypeptide comprising the amino acid sequence lpxtg (seq id no: 20, wherein x can be any amino acid residue), a second polypeptide has an oligo-alanine am (m=2 (seq id no: 26), or 3 (seq id no: 27), or 4 (seq id no: 28), or 5 (seq id no: 29)) ...
Method for purifying target protein
Sysmex Corporation
October 12, 2017 - N°20170292140

Disclosed is a method for purifying a target protein, comprising steps of: bringing a fusion protein containing an amino acid sequence of a peptide tag, an amino acid sequence of a cleavable site of a protease and an amino acid sequence of a target protein, into contact with the protease in a solution, to cleave the peptide tag from the ...
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Compositions and methods for modulating an immune response
Board Of Trustee Of Michigan State University
October 12, 2017 - N°20170292127

The disclosure relates to, among other things, agents that modulate the homophilic interaction between two cracc polypeptides, methods for making such agents, and therapeutic applications in which the agents are useful. For example, the agents described herein are useful for modulating an immune response in a mammal. Also featured are screening methods for identifying additional agents capable of modulating the ...
Beneficial microbes for delivery of effector peptides or proteins and use thereof
Plant Health Care, Inc.
October 12, 2017 - N°20170292108

Disclosed are recombinant host cells comprising a promoter-effective nucleic acid molecule operably coupled to a nucleic acid molecule that encodes a plant effector protein or polypeptide that induces an active plant response including, among others, growth enhancement, disease resistance, pest or insect resistance, and stress resistance. Use of these recombinant host cells for modulating plant biochemical signaling, imparting disease resistance ...
Antibody therapeutics that bind cd38
Sorrento Therapeutics, Inc.
October 12, 2017 - N°20170291959

There is disclosed compositions and methods relating to or derived from anti-cd38 antibodies. More specifically, there is disclosed fully human antibodies that bind cd38, cd38-antibody binding fragments and derivatives of such antibodies, and cd38-binding polypeptides comprising such fragments. Further still, there is disclosed nucleic acids encoding such antibodies, antibody fragments and derivatives and polypeptides, cells comprising such polynucleotides, ...
Peptide Patent Pack
Download 265+ patent application PDFs
Peptide Patent Applications
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For professional research & prior art discovery
inventor
  • 265+ full patent PDF documents of Peptide-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
Antibody therapeutics that bind cd123
Sorrento Therapeutics, Inc.
October 12, 2017 - N°20170291949

There is disclosed compositions and methods relating to or derived from anti-cd123 antibodies. More specifically, there is disclosed fully human antibodies that bind cd123, cd123-antibody binding fragments and derivatives of such antibodies, and cd123-binding polypeptides comprising such fragments. Further still, there is disclosed nucleic acids encoding such antibodies, antibody fragments and derivatives and polypeptides, cells comprising such polynucleotides, ...
Il-17a/f heterologous polypeptides and therapeutic uses thereof
Genentech, Inc.
October 12, 2017 - N°20170291940

The present invention is directed to a novel naturally occurring human cytokine that is comprised of a heterodimer of interleukin-17 and interleukin-17f designated herein as interleukin 17a/f (il-17a/f). Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, ...
Antibodies specific for il-17a fused to hyaluronan binding peptide tags
Novartis Ag
October 12, 2017 - N°20170291939

The present disclosure relates to antibodies and proteins comprising an antigen-binding portion thereof that specifically bind to the pro-inflammatory cytokine il-17a and a peptide tag that binds hyaluronan (ha). The disclosure more specifically relates to specific antibodies and proteins that are il-17a antagonists (inhibit the activities of il-17a and il-17af) and are capable of inhibiting il-17...
Bmprii polypeptides and uses thereof
Acceleron Pharma, Inc.
October 12, 2017 - N°20170291933

In certain aspects, the present disclosure relates to the insight that a polypeptide comprising a ligand-binding portion of the extracellular domain of bone morphogenetic protein receptor type ii (bmprii) polypeptide binds to ligands including bmp10, bmp15, activin b and bmp9 and may be used to treat fibrotic and angiogenic disorders.
Osteogenic biomaterial
Northeast Ohio Medical University
October 12, 2017 - N°20170291932

A composition for enhancing bone tissue repair or regeneration is described. The composition includes osteoactivin or an active peptide fragment thereof and a biocompatible material. Osteogenic orthopedic devices including the osteoactivin-containing composition are also described. The devices and compositions can be used in methods for enhancing bone tissue repair or regeneration by contacting a site in need of bone repair ...
Histatin-5 based synthetic peptides and uses thereof
University Of Maryland, College Park
October 12, 2017 - N°20170291930

Provided herein are synthetic peptides or synthetic fragments thereof based on a histatin-5 peptide, for example with a sequence dshakrhhgykrkfhekhhshrgy (seq id no: 1). The synthetic peptides or synthetic fragments have at least one substituted amino acid that is arginine and/or leucine to increase resistance to proteolytic degradation by a microbe, such as a fungus. The synthetic peptides or synthetic ...
Growth differentiation factor 15 (gdf-15) polypeptides
Amgen Inc.
October 12, 2017 - N°20170291929

Gdf15 polypeptides, constructs comprising gdf15, and mutants thereof are provided. In various embodiments the gdf15 polypeptides, constructs comprising gdf15, and mutants thereof, can be of use in the treatment or ameliorating a metabolic disorder. In various embodiments the metabolic disease or disorder is type 2 diabetes, obesity, dyslipidemia, elevated glucose levels, elevated insulin levels and diabetic nephropathy.
Peptide Patent Pack
Download 265+ patent application PDFs
Peptide Patent Applications
Download 265+ Peptide-related PDFs
For professional research & prior art discovery
inventor
  • 265+ full patent PDF documents of Peptide-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
Modified vip3 polypeptides
Syngenta Participations Ag
October 12, 2017 - N°20170291925

The present invention is directed to vegetative insecticidal proteins (vips) modified to comprise heterologous carbohydrate binding modules and methods of use thereof.
Hypersensitive response elicitor-derived peptides and use thereof
Plant Health Care, Inc.
October 12, 2017 - N°20170291924

Disclosed are hypersensitive-response eliciting peptides and non-hypersensitive response eliciting peptides that induce active plant responses, and that exhibit improved solubility, stability, resistance to chemical degradation, or a combination of these properties. Use of these peptides or fusion polypeptides, or dna constructs encoding the same, for modulating plant biochemical signaling, imparting disease resistance to plants, enhancing plant growth, imparting tolerance to ...
Antibacterial cyclic lipopeptides
The University Of Hong Kong
October 12, 2017 - N°20170291923

Described are design and generation of a set of novel cyclic lipopeptides as potential antibacterial agents. New daptomycin analogues are generated by chemical synthesis, which makes introduction of an unnatural amino acid and any modification into daptomycin possible.
Delta receptor agonist peptides and use thereof
Ariel Scientific Innovations Ltd.
October 12, 2017 - N°20170291922

Peptides effective as delta opioid receptor agonists and compositions comprising same are provided. Further provided are methods for targeting medical conditions amenable to treatment with an opioid receptor agonist, including but not limited to, conditions involving pain as well as reducing cocaine craving.
Cyclic peptide derivative, method for preparing same and composition thereof
Lotte Co., Ltd.
October 12, 2017 - N°20170291921

Provided is a cyclic peptide derivative which is derived from paecilomyces tenuipes having an astrocyte proliferative activity, or a salt thereof.
Soluble intein fusion proteins and methods for purifying biomolecules
Merck Patent Gmbh
October 12, 2017 - N°20170291919

The present invention relates to fusion proteins comprising an n-intein polypeptide and an n-intein solubilization partner, and affinity chromatography matrices comprising such fusion proteins, as well as methods of using same.
Method for purifying protein
Sysmex Corporation
October 12, 2017 - N°20170291918

Disclosed is a method for purifying a protein, comprising steps of: preparing a sample containing a fusion protein containing an amino acid sequence of a peptide tag and an amino acid sequence of a target protein; and separating contaminant proteins contained with the fusion protein in the sample and the fusion protein in the sample, wherein the peptide tag contains 12 ...
Self-assembling peptide scaffolds
Sysmex Corporation
October 12, 2017 - N°20170290951

A mixture for an injectable scaffold may include a self-assembling core and an additive. The additive may include an angiogenic agent, a small molecule drug, and/or an anti-inflammatory agent. The scaffold can be applied to sites where bone growth is desired.
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