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Peptide patents



      

This page is updated frequently with new Peptide-related patent applications.




Date/App# patent app List of recent Peptide-related patents
04/07/16
20160097759 
 Controlled tunnel gap device for sequencing polymers patent thumbnailControlled tunnel gap device for sequencing polymers
The invention includes compositions, devices, and methods for analyzing a polymer and/or polymer unit. The polymer may be a homo or hetero-polymer such as dna, rna, a polysaccharide, or a peptide.
Arizona Board Of Regents On Behalf Of Arizona State University


04/07/16
20160097749 
 Analyte mass spectrometry quantitation using a universal reporter patent thumbnailAnalyte mass spectrometry quantitation using a universal reporter
Quantitation of analytes, including but not limited to peptides, polypeptides, and proteins, in mass spectrometry using a labeled peptide coupled to a reporter, and a universal reporter.. .

04/07/16
20160097084 
 Kinase activity detection methods patent thumbnailKinase activity detection methods
A strategy to take advantage of time-resolved luminescence of ln3+-chelated phosphotyrosine-containing peptides, which facilitate efficient energy transfer to small molecule fluorophores conjugated to the peptides to produce orthogonally-colored biosensors for two different kinases is provided. The method enables multiplexed detection with high signal to noise in a high-throughput-compatible format and a platform that could be applied to other lanthanide metal and fluorophore combinations to achieve even greater multiplexing without the need for phosphospecific antibodies..

04/07/16
20160097080 
 Assays, methods and means patent thumbnailAssays, methods and means
A novel class of hydroxylases is described having the amino acid sequence of seq id no: 2, 4, 6 and 8, and variants and fragments thereof having hif hydroxylation activity. The polypeptides of the invention have in particular prolyl hydroxylase activity.
Isis Innovation Limited


04/07/16
20160097079 
 Assays, methods and means patent thumbnailAssays, methods and means
A novel class of hydroxylases is described having the amino acid sequence of seq id no: 2, 4, 6 and 8, and variants and fragments thereof having hif hydroxylation activity. The polypeptides of the invention have in particular prolyl hydroxylase activity.
Isis Innovation Limited


04/07/16
20160097078 
 Assays, methods and means patent thumbnailAssays, methods and means
A novel class of hydroxylases is described having the amino acid sequence of seq id no: 2, 4, 6 and 8, and variants and fragments thereof having hif hydroxylation activity. The polypeptides of the invention have in particular prolyl hydroxylase activity.
Isis Innovation Limited


04/07/16
20160097077 
 Assays, methods and means patent thumbnailAssays, methods and means
A novel class of hydroxylases is described having the amino acid sequence of seq id no: 2, 4, 6 and 8, and variants and fragments thereof having hif hydroxylation activity. The polypeptides of the invention have in particular prolyl hydroxylase activity.
Isis Innovation Limited


04/07/16
20160097076 
 Assays, methods and means patent thumbnailAssays, methods and means
A novel class of hydroxylases is described having the amino acid sequence of seq id no: 2, 4, 6 and 8, and variants and fragments thereof having hif hydroxylation activity. The polypeptides of the invention have in particular prolyl hydroxylase activity.
Isis Innovation Limited


04/07/16
20160097050 
 Devices and methods for display of encoded peptides, polypeptides, and proteins on dna patent thumbnailDevices and methods for display of encoded peptides, polypeptides, and proteins on dna
A novel method for displaying proteins and peptides is disclosed in which individual proteins or peptides remain associated with the dna encoding them. Proteins or peptides can be generated by in vitro translation of dna templates, either free in solution or arrayed on a solid support, such that the proteins or peptides remain immobilized on their dna templates.
The Board Of Trustees Of The Leland


04/07/16
20160097042 
 Internal protein tags patent thumbnailInternal protein tags
Provided herein are substantially non-luminescent peptide/polypeptide tags that are inserted internally within a protein of interest or between n-terminal and c-terminal peptides/polypeptides. Interaction of the internally-inserted tag with a complement polypeptide/peptide that is also substantially non-luminescent results in the formation a bioluminescent reporter complex)..
Promega Corporation


04/07/16
20160096898 

Pc33718e


The present invention provides antagonizing antibodies, antigen-binding portions thereof, and aptamers that bind to proprotein convertase subtilisin kexin type 9 (pcsk9). Also provided are antibodies directed to peptides, in which the antibodies bind to pcsk9.
Rinat Neuroscience Corp.


04/07/16
20160096890 

B7-h1, a novel immunoregulatory molecule


The invention provides novel polypeptides useful for co-stimulating t cells, isolated nucleic acid molecules encoding them, vectors containing the nucleic acid molecules, and cells containing the vectors. Also included are methods of making and using these co-stimulatory polypeptides..
Mayo Foundation For Medical Education And Research


04/07/16
20160096889 

B7-h1, a novel immunoregulatory molecule


The invention provides novel polypeptides useful for co-stimulating t cells, isolated nucleic acid molecules encoding them, vectors containing the nucleic acid molecules, and cells containing the vectors. Also included are methods of making and using these co-stimulatory polypeptides..
Mayo Foundation For Medical Education And Research


04/07/16
20160096884 

Antibodies directed against amyloid-beta peptide and methods using same


Antibodies directed to the c-terminal side of β-amyloid peptide and methods of using these antibodies for diagnosing and treatment of alzheimer's disease and aβ peptide associated diseases are described.. .
Rinat Neuroscience Corp.


04/07/16
20160096877 

Apoe peptide dimers and uses thereof


The present invention provides novel pharmaceutical compositions comprising apoe-derived peptide dimers. In particular, the apoe peptide dimers of the invention comprise at least two apoe mimetic domains and can comprise one or more protein transduction domains.
Cognosci, Inc.


04/07/16
20160096873 

Peptidomimetic macrocycles


The present invention provides biologically active crosslinked polypeptides with improved properties relative to their corresponding precursor polypeptides, having good cell penetration properties and reduced binding to human proteins. The invention additionally provides methods of identifying and making such improved polypeptides..
Aileron Therapeutics, Inc.


04/07/16
20160096872 

Methods for producing peptides using engineered inteins


The present invention provides a method for producing peptides by recombinant means. The peptides are expressed as part of a fusion protein comprising the target peptide and an engineered intein.
Novo Nordisk A/s


04/07/16
20160096869 

Chlorotoxin conjugates and methods of use thereof


Compositions, formulations and kits comprising chlorotoxin conjugate compounds are provided, including native and modified variants of chlorotoxin peptide conjugated to reporter molecules including fluorescent dyes. Methods of detecting and treating cancers and tumors with chlorotoxin conjugate compounds are also provided, including methods of imaging tumor tissues and cells.
Blaze Bioscience, Inc.


04/07/16
20160096868 

Mussel-inspired bioactive surface coating composition generating silica nanoparticles


The present invention relates to a fusion protein comprising a mussel adhesive protein and a silica-binding peptide linked to the mussel adhesive protein, a silica nanoparticle a silica connected to the fusion protein, a fusion protein-silica nanoparticle complex comprising the silica nanoparticle having bioactivity and adhesiveness for cell proliferation and accelerating the differentiation, a surface coating composition including the complex, its use, and a method of coating a surface using the surface coating composition.. .
Postech Academy-industry Foundation


04/07/16
20160096867 

Conformationally-preorganized, minipeg-containing gamma-peptide nucleic acids


The present invention relates to γ-pna monomers according to formula i where substituent groups r1, r2, r3, r4, r5, r6, b and p are defined as set forth in the specification. The invention also provides methodology for synthesizing compounds according to formula i and methodology for synthesizing pna oligomers that incorporate one or more formula i monomers..
Carnegie Mellon University Center For Technology Transfer & Enterprise


04/07/16
20160096866 

Potent compstatin analogs


Compounds comprising peptides and peptidomimetics capable of binding c3 protein and inhibiting complement activation are disclosed. These compounds display greatly improved complement activation-inhibitory activity as compared with currently available compounds.
The Trustees Of The University Of Pennsylvania


04/07/16
20160096865 

Peptide-silica hybrid materials


The invention relates to novel peptide-silane “hybrid block” molecules, to the synthesis thereof and to the use of same for producing novel peptide-silica hybrid materials that can be used in various applications.. .
Universite De Montpellier I


04/07/16
20160095954 

Fibrin microthreads


Compositions that include fibrin microthreads are provided. The compositions can include one or more therapeutic agents including cytokines and interleukins, extracellular matrix proteins and/or biologically active fragments thereof (e.g., rgd-containing peptides), hormones, vitamins, nucleic acids, chemotherapeutics, antibiotics, and cells.
Worcester Polytechnic Institute


04/07/16
20160095937 

Interfering rna delivery system and uses thereof


The invention provides a delivery system comprising a cell penetrating peptide, a polyarginine peptide, and an interfering rna molecule. The system can be used for delivering interfering rna molecules into a cell in vivo or in vitro.
Arrowhead Research Corporation


04/07/16
20160095936 

Immunostimulatory compositions and methods of use thereof


Lipid conjugates for enhanced delivery of cargo to the lymph nodes are disclosed. The lipid conjugates typically include three domains: a lipophilic domain that binds to albumin, a polar block domain, and a cargo such as a molecular adjuvant or immunostimulatory compound (such as an oligonucleotide) or antigenic peptide.
Massachusetts Institute Of Technology


04/07/16
20160095918 

Rapid, efficient purification of hsv-specific t-lymphocytes and hsv antigens identified via same


A method of identifying an immunologically active antigen of a virus that attacks skin, as well as a method of enriching a population of lymphocytes for t lymphocytes that are specific to a virus that attacks skin. Also provided are hsv antigens and epitopes that are useful for the prevention and treatment of hsv infection that have been identified via the methods of the invention.
University Of Washington


04/07/16
20160095917 

Dps fusion proteins for use in vaccines and diagnostics


Novel nanoparticle fusion proteins comprising proteins or peptides fused to dps (dna binding protein from starved cells) proteins are provided which bring forth distinct advantages for development of new and improved vaccines, diagnostic tests, and other biomedical products.. .
Kj Biosciences Llc


04/07/16
20160095916 

Induction of cross-reactive cellular response against rhinovirus antigens


The present invention concerns: a) an isolated peptide comprising an amino acid sequence which is at least 90% identical to the vp4 amino acid sequence of a rhinovirus, or an isolated polynucleotide comprising a nucleic acid sequence encoding said peptide, placed under the control of the elements necessary for its expression in a mammalian cell; and/or b) an isolated peptide comprising an amino acid sequence of at least 100 amino acids which is at least 90% identical to an amino acid sequence located in the last 363 c-terminal amino acids of the rna polymerase of a rhinovirus, or an isolated polynucleotide comprising a nucleic acid sequence encoding said peptide, placed under the control of the elements necessary for its expression in a mammalian cell; and c) a th1 adjuvant when said immunogenic composition comprises one or more of said isolated peptides.. .
Imperial Innovations Limited


04/07/16
20160095910 

Self-assembling synthetic proteins


The present disclosure provides for a synthetic immunogenic protein for use as an immuno-modulatory agent to enhance mammalian immune reactions towards conjugated protein or peptide containing antigens that are otherwise poorly immunogenic, including but not limited to self-antigens. The chimeric immunogenic proteins of the present disclosure can be used in the treatment of many illnesses, including but not limited to cancers, infectious disease, autoimmune disease, allergies and any clinical indication involving or affected by the immune response of a mammalian host..

04/07/16
20160095909 

Methods of preventing rejection of transplanted tissue by administering anti-cd40l antibody and dendritic cells loaded with type b peptide


A method is provided for preventing rejection by an immune system of a recipient subject of a tissue transplanted from a donor subject into the recipient subject without the need for long-term administration of non-specific immunosuppressive drugs.. .
The Trustees Of Columbia University In The City Of New York


04/07/16
20160095899 

Allergen peptide fragments and use thereof for treatment of birch pollen allergies


The present invention relates generally to in vivo methods and compositions designed for allergen specific immunotherapy. The compositions include contiguous overlapping peptide fragments which together form an entire amino acid sequence of an allergen..
Anergis S.a.


04/07/16
20160095814 

Cosmetic compositions


Disclosed are compositions and methods for their use that can be used in cosmetic applications. The composition can include an effective amount of a centella asiatica stem cells to reduce the activity of hyaluronidase in skin, an effective amount of tetradecyl aminobutyroylvalylamino butyric urea trifluoroacetate or alpinia galanga leaf extract to promote the production of hyaluronic acid in skin, an effective amount of tripeptide-1 to promote the production of fibronectin and laminin in skin, and a dermatologically acceptable vehicle..
Mary Kay Inc.


04/07/16
20160095316 

Compositions and methods for the removal of biofilms


Methods of breaking down a biofilm or inhibiting, preventing or treating a microbial infection that produces a biofilm are disclosed, which involves administration of a polypeptide that has one or more hmg-box domains to a subject suffering from the infection or having the biofilm. By competing with microbial proteins that bind to dna scaffold in the biofilm, these polypeptides destabilize the biofilm leading to destruction and removal of the biofilm by the immune system..

04/07/16
20160095315 

Elicitor peptides having disrupted hypersensitive response box and use thereof


Disclosed are peptides that induce an active plant response, but not a hypersensitive response, when applied to plant tissue. These peptides also preferably exhibit improved solubility, stability, resistance to chemical degradation, or a combination of these properties.
Plant Health Care, Inc.


04/07/16
20160095314 

Hypersensitive response elicitor peptides and use thereof


Disclosed are hypersensitive-response eliciting peptides that exhibit improved solubility, stability, resistance to chemical degradation, or a combination of these properties. Use of these peptides or fusion polypeptides, or dna constructs encoding the same, for modulating plant biochemical signaling, imparting disease resistance to plants, enhancing plant growth, imparting tolerance to biotic stress, imparting tolerance and resistance to abiotic stress, imparting desiccation resistance to cuttings removed from ornamental plants, imparting post-harvest disease or post-harvest desiccation resistance to a fruit or vegetable, or enhancing the longevity of fruit or vegetable ripeness are also disclosed..
Plant Health Care, Inc.


03/31/16
20160091507 

Sensors for assaying coagulation in fluid samples


The present invention relates to analytical testing devices including micro-environment sensors and methods for assaying coagulation in a fluid sample applied to the micro-environment sensors, and in particular, performing one or more types of coagulation assays using one or more micro-environment sensors in a single point of care combined test cartridge. For example, the present invention may be directed to test sensor including at least one transducer coated with a polymer layer.
Abbott Point Of Care Inc.


03/31/16
20160091502 

Fibrosis biomarker assay


Methods of diagnosis or of quantitation of fibrosis are provided that comprise conducting an immunoassay to measure neo-epitope containing protein fragments naturally present in a biofluid sample, and associating an elevation of the measure in the patient above a normal level with the presence or extent of fibrosis. The immunoassay is conducted by a contacting protein fragments naturally present in the sample with an immunological binding partner reactive with a neo-epitope formed by cleavage of a protein by a proteinase and measuring the extent of binding of peptide fragments to the immunological binding partner to measure therein protein fragments comprising the neo-epitope.
Nordic Bioscience A/s


03/31/16
20160091500 

Chondroadherin fragments as indicators of intervertebral disc degeneration


The present disclosure concern fragments of the chondroadherin (chad) polypeptide which are generated during the proteolytic cleavage of the third leucine repeat motif of the chad polypeptide. Such fragments are generated and thus associated with the onset and progression of intervertebral disc degeneration and can be used to assess the risk of a subject to develop intervertebral disc degeneration or to determine if the subject is afflicted by intervertebral disc degeneration.

03/31/16
20160091492 

Method for the detection, preparation and depletion of cd4+ t lymphocytes


The present invention relates an in vitro method for detecting class ii restricted cd4+ t cells in a sample. Herein a sample is contacted with an isolated complex of an mhc class ii molecule and a peptide.
Imcyse Sa


03/31/16
20160090605 

Drought-tolerant transgenic plant


Described herein is a transgenic plant that comprises a recombinant dna construct that contains a nucleic acid sequence operably linked to a promoter, the nucleic acid sequence encoding an afl1 polypeptide, a recombinant dna construct for inhibiting expression of a pd15 polypeptide or a nai2 polypeptide, or a loss-of-function pdi5 or nai2 mutation, wherein the transgenic plant exhibits increased growth under drought as compared to a control plant.. .
Academia Sinica


03/31/16
20160090603 

Delivery platforms for the domestication of algae and plants


The present invention relates to a delivery platform that can be used to genetically modify a target in a plant or an alga. In one instance, polypeptides and/or polynucleotides can be delivered using silica delivery platforms, e.g., silica carriers or protocells.
Sandia Corporation


03/31/16
20160090601 

Production of polypeptides relevant to human and animal health using yarrowia lipolytica


The present invention relates to the expression of polypeptides using yarrowia lipolytica, in particular the secretion of expressed polypeptides into either the extracellular space or the surface of the y. Lipolytica host cell wall.
University Of The Free State


03/31/16
20160090585 

Isomerases, nucleic acids encoding them and methods for making and using them


This invention relates generally to enzymes, polynucleotides encoding the enzymes, the use of such polynucleotides and polypeptides and more specifically to enzymes having isomerase activity, e.g., racemase activity, e.g., amino acid racemase activity, alanine racemase activity, and/or epimerase activity, and/or catalyze the re-arrangement of atoms within a molecule, catalyze the conversion of one isomer into another, catalyze the conversion of an optically active substrate into a raceme, which is optically inactive, catalyze the interconversion of substrate enantiomers, catalyze the stereochemical inversion around the asymmetric carbon atom in a substrate having only one center of asymmetry, catalyze the stereochemical inversion of the configuration around an asymmetric carbon atom in a substrate having more than one asymmetric center, and/or catalyze the racemization of amino acids. Thus, the invention provides enzymes, compositions, methods for production of pharmaceutical compositions, pharmaceutical intermediates, antibiotics, sweeteners, peptide enzymes, peptide hormones, fuel and fuel additive compositions, foods and food additives, beverage and beverage additives, feeds and feed additives, drugs and drug additives, dietary supplements, textiles, wood, paper, pulp, and detergents comprising the polypeptides or polynucleotides in accordance with the invention..
Basf Enzymes Llc


03/31/16
20160090427 

Polypeptide, anti-vegf antibody, and anti-c-met/anti-vegf bispecific antibodies comprising the same


A polypeptide, an anti-vegf antibody and an anti-c-met/anti-vegf bispecific antibody, which includes the polypeptide, a pharmaceutical composition including the antibody, and a method of treating cancer using the antibody.. .
Samsung Electronics Co., Ltd.


03/31/16
20160090424 

Stable formulations of immunoglobulin single variable domains and uses thereof


The present invention relates to stable formulations of polypeptides, e.g. Immunoglobulin single variable domains, in particular immunoglobulin single variable domains directed against von willebrand factor (vwf).
Ablynx N.v.


03/31/16
20160090409 

Methods for the treatment of neurodegeneration


The invention encompasses the discovery that fc-containing polypeptides that include branched glycans and that are sialylated on the branched glycan (e.g., on an α 1,3 and/or α 1,6 arm in the fc region's n-linked glycosylation site), with, e.g., a neuac-α 2,6-gal or neuac-α 2,3-gal terminal linkage, are useful in treating neurodegeneration, e.g., in the treatment of neurodegenerative diseases such as alzheimer's disease. The present disclosure provides, in part, methods for treating neurodegeneration or neurodegenerative diseases by administering compositions containing such fc-containing polypeptides as well as methods for evaluating, identifying, and/or producing (e.g., manufacturing) such polypeptides for the treatment of neurodegeneration..
Momenta Pharmaceuticals, Inc.


03/31/16
20160090408 

Anti-angiogenic agent and methods of using such agent


Anti-angiogenic agents or polypeptides comprising an amino acid segment substantially similar to domain one of cd2 wherein the polypeptide has a β-sheet formed by two segments. Methods of using such agents and polypeptide are also included..
Georgia State Research Foundation


03/31/16
20160090405 

Engineered microorganisms having resistance to ionic liquids


The present invention provides for a method of genetically modifying microorganisms to enhance resistance to ionic liquids using a yeast major facilitator superfamily (mfs), or a salmonella mfs smva pump or smvr regulator, a small multidrug resistance family (smr), or saccharomyces cerevisiae ydr090c, polypeptide, host cells genetically modified in accordance with the methods, and methods of using the host cells in a reaction comprising biomass that has been pretreated with ionic liquids.. .
Lawrence Livermore National Security, Llc


03/31/16
20160090403 

Virus like particle composition


The present invention provides a particle comprising a polypeptide and at least one antigen, and a composition comprising thereof.. .
Vlp Therapeutics, Llc


03/31/16
20160090402 

Peptide domain required for interaction between the envelope of a virus pertaining to the herv-w interference group and an hasct receptor


A peptide domain necessary for an interaction between an envelope of a virus belonging to an herv-w interference group and an hasct receptor comprises (i) an n-terminus motif having an amino acid sequence selected from the group consisting of: seq id no. 1 to seq id no.
Biomerieux


03/31/16
20160090401 

Self-assembling peptide cages from coiled-coil peptide modules


This invention relates to protein structures, to methods of producing those protein structures, and to peptides used in the formation of the protein structures.. .
The University Of Bristol


03/31/16
20160089447 

Cell penetrating peptides for intracellular delivery of molecules


A cell-penetrating peptide characterized in that it comprises an amino acid sequence x3x4x1x2x5x4x1x2x6x7x1x8x9x10x11x12x13 (seq id no: 11), wherein x1 is f or w, x2 is f, w or y, x3 is beta-a or s, x4 is k, r or l, x5 is e, r or s, x6 is r. T or s, x7 is e, r or s, x8 is none, f or w, x9 is p or r, x10 is r or l, x11 is k, w or r, x12 is r or f and x13 is r or k..
Centre National De La Recherche Scientifique


03/31/16
20160089432 

Methods and compositions for inducing protective immunity against human immunodeficiency virus infection


Compositions, vaccines and methods for inducing protective immunity against human immunodeficiency virus (hiv) infection are described. Heterologous vaccine combinations of one or more viral expression vectors and an isolated antigenic polypeptide induced strong protective immunity against infections by one or multiple clades of hiv..
Crucell Holland B.v.


03/31/16
20160089431 

Nanodisk-associated immunogen super polyvalent vaccines


Disclosed are compositions of matter consisting of collections of nanodisks associated with polypeptide immunogens. Each said collection contains multiple epitopes of at least one immunogen.
Shiva Science & Technology Group Llc


03/31/16
20160089416 

Method of treating cancer


This disclosure pertains to a method of treating liver cancer using a peptide based on venom from a terebrid snail, terebrid variegata. The venom has a general formula of trx3ccgcywngskdvcsqscc (seq id no.
Research Foundation Of The City University Of New York


03/31/16
20160089413 

Use of cell-permeable peptide inhibitors of the jnk signal transduction pathway for the treatment of chronic or non-chronic inflammatory eye diseases


The present invention refers to the use of protein kinase inhibitors and more specifically to the use of inhibitors of the protein kinase c-jun amino terminal kinase, jnk inhibitor (poly-)peptides, chimeric peptides, or of nucleic acids encoding same as well as pharmaceutical compositions containing same, for the treatment of non-chronic or chronic inflammatory eye diseases, such as inflammatory diseases of the blephara, conjunctiva, cornea, sclera, the vitreous body, uvea, ciliary body, choroid, orbital bone, lacrimal gland, or iris, in particular wherein the inflammatory disease is selected from hordeolum, chalazion, conjunktivitis, keratitis, scieritis, episcleritis, endophthalmitis, panophtalmitis, irititis, uveitis, cyclitis, chorioiditis, orbital phlegmon, and myositis of the eye muscle etc.. .
Xigen Inflammation Ltd.


03/31/16
20160089385 

Vitamin d receptor agonists to treat diseases involving cxcl12 activity


Provided herein are methods of treating and preventing pancreatitis, such as pancreatitis induced by glucagon-like peptide (glp) agonists (such as glp-1 agonists, for example byetta®), by administration of a vitamin d receptor agonist (such as vitamin d, vitamin d analogs, vitamin d precursors, and vitamin d receptor agonists precursors). In some examples the subject has diabetes, such as type 2 diabetes..
Salk Institute For Biological Studies


03/24/16
20160086782 

Species detection using mass spectrometry


Systems and methods are provided for species detection using mass spectrometry. In various embodiments, a multiple reaction monitoring (mrm) experiment is performed on a sample targeting one or more peptide transitions that are unique to one or more species using a tandem mass spectrometer.
Dh Technologies Development Pte. Ltd.


03/24/16
20160084852 

Methods of determination of activation or inactivation of atrial natriuretic peptide (anp) and brain natriuretic peptide (bnp) hormonal systems


An in vivo method of determining activation or inactivation of the atrial natriuretic peptide (anp) and brain natriuretic peptide (bnp) hormonal systems, the method comprising simultaneously detecting the presence or amount of atrial and brain natriuretic peptide prohormones (proanp and probnp) or fragments thereof in a sample.. .
Orion Diagnostica Oy


03/24/16
20160084850 

Method for quantifying glycated hemoglobin


A method for quantifying glycated hemoglobin (hba1c) contained in a sample, the method including: (a) a process for mixing the sample with a protease in the presence of a composition of a cationic surfactant and a tetrazolium salt to obtain an aqueous glycated peptide solution containing a glycated peptide; (b) a process for mixing the aqueous glycated peptide solution obtained in process (a) with a fructosyl peptide oxidase to obtain hydrogen peroxide, the aqueous glycated peptide solution here containing the composition; and (c) a process for calculating the concentration of the glycated hemoglobin (hba1c) on the basis of the amount of hydrogen peroxide solution obtained in process (b).. .
Panasonic Healthcare Holdings Co., Ltd.


03/24/16
20160084844 

Methods of identifying glycopeptides recognized by disease-associated auto-antibodies


Methods for identifying glycopeptides and more particularly glycopeptide epitopes that are specifically recognized by disease-associated auto-antibodies are provided. In some aspects the auto-antibodies are cancer-associated or autoimmune disease associated.
Glycozym, Inc.


03/24/16
20160084841 

Method for predicting clinical effect of immunotherapy


Provided is a method for predicting a clinical effect on a subject in a wt1 peptide immunotherapy, said method comprising: a) a step for contacting a sample derived from the subject with wt1 antigen peptide or a variant thereof; and b) a step for detecting the binding of the sample to the wt1 antigen peptide or a variant thereof and thus measuring anti-wt1 antigen peptide igg antibody titer existing in the sample, characterized in that an increase in the anti-wt1 antigen peptide igg antibody titer in the subject determines the achievement of a favorable clinical effect. Also provided is a kit for performing the method according to the present invention, said kit containing wt1 antigen peptide or a variant thereof..
International Institute Of Cancer Immunology, Inc.


03/24/16
20160084829 

Self-assembled peptide nanostructures by exploiting conformational change, biosensor using the same and detection biomolecules using the same


The present disclosure relates to a self-assembled peptide nanostructure including at least one amphiphilic peptide and a biosensor using the same. The amphiphilic peptide is a hairpin-shaped amphiphilic peptide including a hydrophilic domain having an α-helical structure and a hydrophobic domain.
Industry-academic Cooperation Foundation, Yonsei University


03/24/16
20160084825 

Stabilized low affinity conformation of integrins for drug discovery


The methods and compositions described herein are based, in part, on the discovery that the introduction of a disulfide bond into an integrin polypeptide by the substitution of at least one cysteine residue in the polypeptide permits stabilization of the integrin in a “closed/inactive” state. This stabilizing disulfide bond permits integrins to be screened for a candidate molecule that can bind to the closed state.
Children's Medical Center Corporation


03/24/16
20160084821 

Methods and compositions for the diagnosis of cancer susceptibilities and defective dna repair mechanisms and treatment thereof


Methods and compositions for the diagnosis of cancer susceptibilities, defective dna repair mechanisms and treatments thereof are provided. Among sequences provided here, the fancd2 gene has been identified, and probes and primers are provided for screening patients in genetic-based tests and for diagnosing fanconi anemia and cancer.
Oregon Health And Science University






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This listing is a sample listing of patent applications related to Peptide for is only meant as a recent sample of applications filed, not a comprehensive history. There may be associated servicemarks and trademarks related to these patents. Please check with patent attorney if you need further assistance or plan to use for business purposes. This patent data is also published to the public by the USPTO and available for free on their website. Note that there may be alternative spellings for Peptide with additional patents listed. Browse our RSS directory or Search for other possible listings.


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