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Peptide patents



      
           
This page is updated frequently with new Peptide-related patent applications. Subscribe to the Peptide RSS feed to automatically get the update: related Peptide RSS feeds. RSS updates for this page: Peptide RSS RSS


Date/App# patent app List of recent Peptide-related patents
12/18/14
20140373199
 Polypeptides having beta-xylosidase activity and polynucleotides encoding same patent thumbnailnew patent Polypeptides having beta-xylosidase activity and polynucleotides encoding same
Provided are isolated polypeptides having beta-xylosidase activity and polynucleotides encoding the polypeptides. Also provided are nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides..
12/18/14
20140373198
 Plant genes involved in nitrate uptake and metabolism patent thumbnailnew patent Plant genes involved in nitrate uptake and metabolism
The present invention relates nucleic acid molecules that are modulated (e.g., upregulated) by nitrogen in corn, to proteins or polypeptides encoded by these nucleic acid molecules, and promoters of these nucleic acid molecules. The present invention relates to a nucleic acid construct having a nucleic acid molecule that is modulated by nitrogen in corn, as well as to expression systems, host cells, plants, and plant seeds having the nucleic acid construct.
12/18/14
20140373195
 Axmi345 delta-endotoxin gene and methods for its use patent thumbnailnew patent Axmi345 delta-endotoxin gene and methods for its use
Compositions and methods for conferring pesticidal activity to bacteria, plants, plant cells, tissues and seeds are provided. Compositions comprising a coding sequence for a toxin polypeptide are provided.
12/18/14
20140371431
 Process for preparation of secretory iga and secretory igm patent thumbnailnew patent Process for preparation of secretory iga and secretory igm
A process for synthesizing and separating secretory iga from a mixture of iga monomer and iga dimer is provided. The process includes covalently binding affinity tagged or epitope tagged recombinant secretory component to the iga dimer in the mixture and binding the affinity tagged or an epitope tagged secretory iga to immobilized moieties on the solid phase support resin to which the affinity tag or epitope tag binds and then eluting the affinity tagged or an epitope tagged secretory iga with release buffer.
12/18/14
20140371429
 Methods and composition for secretion of heterologous polypeptides patent thumbnailnew patent Methods and composition for secretion of heterologous polypeptides
The present invention relates generally to the fields of molecular biology and protein technology. More specifically, the invention concerns signal sequences for the secretion of heterologous polypeptide from bacteria.
12/18/14
20140371424
 Benzylic compound patent thumbnailnew patent Benzylic compound
The present invention provides a protecting reagent that can be removed in a high yield even under acidic conditions and can afford a resulting product at a high purity in an organic synthesis reaction such as peptide synthesis and the like. The inventive protecting reagent is particular benzylic compound having only one hydroxyl group substituted by an organic group having an aliphatic hydrocarbon group having a carbon number of not less than 14..
12/18/14
20140371302
 Modified mrnas encoding cell-penetrating polypeptides patent thumbnailnew patent Modified mrnas encoding cell-penetrating polypeptides
This invention relates to modified nucleic acid compositions encoding cell-penetrating polypeptides to provoke an innate immune response in a cell and methods of delivering protein-binding partners to target cells.. .
12/18/14
20140371299
 Use of apoptosis-specific elf-5a sirna to down regulate expression of proinflammatory cytokines to treat sepsis patent thumbnailnew patent Use of apoptosis-specific elf-5a sirna to down regulate expression of proinflammatory cytokines to treat sepsis
The present invention relates to apoptosis specific eucaryotic initiation factor 5a (eif-5a), referred to as apoptosis-specific eif-5a or eif5-a1, nucleic acids and polypeptides and methods for down regulating pro-inflammatory cytokines in a mammal by administering sirna against eif-5a1 to the mammal to treat/prevent sepsis and/or hemorrhagic shock.. .
12/18/14
20140371294
 Compositions and methods comprising histidyl-trna synthetase splice variants having non-canonical biological activities patent thumbnailnew patent Compositions and methods comprising histidyl-trna synthetase splice variants having non-canonical biological activities
Isolated histidyl-trna synthetase splice variant polynucleotides and polypeptides having non-canonical biological activities are provided, as well as compositions and methods related thereto.. .
12/18/14
20140371261
 Indomethacin analogs for the treatment of castrate-resistant prostate cancer patent thumbnailnew patent Indomethacin analogs for the treatment of castrate-resistant prostate cancer
Provided are compositions for inhibiting a biological activity of an aldoketo reductase family 1, member c3 (akr1 c3) polypeptide. In some embodiments, the compositions are indomethacin derivatives that are akr1 c3-specific inhibitors.
12/18/14
20140371255
new patent Non-peptidyl, potent, and selective mu opioid receptor antagonists and their use in treating opioid addiction and opioid induced constipation
Selective, non-peptide antagonists of the mu opioid receptor (mor) and methods of their use are provided. The antagonists may be used, for example, to identify mor agonists in competitive binding assays, and to treat conditions related to addiction in which mor is involved, e.g.
12/18/14
20140371161
new patent Novel peptides and methods and uses thereof for preventing retinal disorders
The present disclosure relates to methods and uses of c-terminal peptides for inhibiting neuronal cell death or dysfunction, such as retinal ganglion cell death or dysfunction, treating retinal degenerative disorders, stroke, cns and pns insults. The disclosure also relates to the c-terminal peptides, fusion proteins and compositions thereof..
12/18/14
20140371156
new patent Membrane resident peptide in anti-cancer peptides causes tumor cell necrosis rather than apoptosis of cancer cells
An aspect of the invention provides a method of selectively necrosing cells, comprising: providing a plurality cells, including at least one cancer cell and at least one non-cancerous cell; and administering to the cells a compound, including an hdm-2 targeting component and a cytotoxic component attached to the hdm-2 targeting component, wherein said compound comprises a membrane-active form.. .
12/18/14
20140371155
new patent Nucleic acids encoding peptides for treating wounds, anti-angiogenic compounds and uses thereof
The present disclosure relates to protein and peptide chemistry. More particularly, it relates to compounds, compositions and uses thereof for promoting and inhibiting angiogenesis.
12/18/14
20140371154
new patent Nucleic acids encoding peptides for treating wounds, anti-angiogenic compounds and uses thereof
The present disclosure relates to protein and peptide chemistry. More particularly, it relates to compounds, compositions and uses thereof for promoting and inhibiting angiogenesis.
12/18/14
20140371153
new patent Method for administering omega-conopeptide
The present invention is directed to a method of producing analgesia in a mammalian subject. The method includes administering to the subject an omega conopeptide, preferably ziconotide, in combination with an analgesic selected from the group consisting of morphine, bupivacaine, clonidine, hydromorphone, baclofen, fentanyl 1, buprenorphine, and sufentanil, or its pharmaceutically acceptable salts thereof, wherein the ω-conopeptide retains its potency and is physically and chemically compatible with the analgesic compound.
12/18/14
20140371152
new patent Amyloid beta-protein-specific production-inhibiting polypeptide
This object can be achieved by a polypeptide having the amino acid sequence represented by any one of seq id nos: 1, 13, 14, and 22, that binds to the n-terminal region of βctf; a γ-secretase activity inhibitor containing the polypeptide; β-secretase activity inhibitor; aβ protein production inhibitor; and an agent for treating and/or preventing alzheimer's disease.. .
12/18/14
20140371150
new patent Peptides targeting receptor activator of nuclear factor - kappa b (rank) and their applications
The present invention relates to a polypeptide for use as a medicament in the treatment and/or prevention of a disease wherein the rankl-rank signaling pathway is involved, in particular a bone resorptive disease.. .
12/18/14
20140371148
new patent Peptide-peptidase inhibitor conjugates and methods of using same
Peptide-peptidase inhibitor conjugate molecules are disclosed. These conjugate molecules are useful as agents for the treatment and prevention of metabolic and cardiovascular diseases, disorders, and conditions.
12/18/14
20140371144
new patent Long-acting growth hormone and methods of producing same
Use of a growth hormone protein and polynucleotides encoding same comprising an amino-terminal carboxy-terminal peptide (ctp) of chorionic gonadotrophin and two carboxy-terminal chorionic gonadotrophin ctps attached to the growth hormone in methods of inducing weight loss or body fat reduction, methods of increasing insulin-like growth factor (igf-1) levels, and methods of reducing the dosing frequency of a growth hormone in a human subject are disclosed. Pharmaceutical compositions comprising the growth hormone and polynucleotides encoding the growth hormone of the invention and methods of using same are also disclosed..
12/18/14
20140371143
new patent New peptide inhibiting rankl-rank interaction and the use thereof
Provided are a peptide for inhibiting an interaction between an rankl and an rank consisting of an amino acid sequence of seq id no: 1 and a pharmaceutical composition for preventing or treating bone diseases including the peptide. The peptide consisting of an amino acid sequence of seq id no: 1 is not present in a cyclic shape, and has 10 or less amino acids, thereby having better biostability than a conventional peptide to inhibit an rankl-rank interaction, being preferable in price during synthesis, and having a better rankl-rank interaction inhibitory effect.
12/18/14
20140371142
new patent Myonectin (ctrp15), compositions comprising same, and methods of use
Disclosed is the novel myokine known as myonectin (ctrp15), an isolated nucleic acid encoding the myonectin (ctrp15) gene, and the amino acid sequence encoding the myonectin (ctrp15) protein. Methods of isolation of the nucleic acid, protein, polypeptides and methods of making antibodies to the myonectin (ctrp15) protein are provided.
12/18/14
20140371136
new patent Growth hormone polypeptides and methods of making and using same
The present invention relates to compositions comprising growth hormone linked to extended recombinant polypeptide (xten), isolated nucleic acids encoding the compositions and vectors and host cells containing the same, and methods of making and using such compositions in treatment of growth hormone-related diseases, disorders, and conditions.. .
12/18/14
20140371135
new patent High purity lipopeptides
The invention discloses highly purified daptomycin and to pharmaceutical compositions comprising this compound. The invention discloses a method of purifying daptomycin comprising the sequential steps of anion exchange chromatography, hydrophobic interaction chromatography and anion exchange chromatography.
12/18/14
20140371091
new patent Programmable arrays
Biomolecule arrays on a substrate are described which contain a plurality of biomolecules, such as coding nucleic acids and/or isolated polypeptides, at a plurality of discrete, isolated, locations. The arrays can be used, for example, in high throughput genomics and proteomics for specific uses including, but not limited molecular diagnostics for early detection, diagnosis, treatment, prognosis, monitoring clinical response, and protein crystallography..
12/18/14
20140371079
new patent Cancer-targeting peptides and uses thereof in cancer treatment and diagnonsis
Cancer-targeting peptides having a px1lx2 motif, in which x1 is his or an amino acid residue with a hydrophobic side chain and x2 is pro, phe, or trp. Also disclosed herein are conjugates containing the cancer-targeting peptides and uses thereof in cancer treatment and diagnosis..
12/18/14
20140370620
new patent Multimer type discrimination and detection method for multimer-forming polypeptide
The present invention relates to a method for selectively detecting a multimer type multimer-forming polypeptide in a biological sample, the method comprising: (a) bringing the biological sample into contact with an agglutination reaction inducing agent to induce the formation of an aggregate in an analysis target, the agglutination reaction inducing agent being a particle in which a specific antibody is surface-bonded with the multimer-forming polypeptide; (b) obtaining an image with respect to the aggregate of step (a); and (c) analyzing a size or a shape of the aggregate by using the image. Step (a), step (b), or steps (a) and (b) are performed on a microchip having a microchannel.
12/18/14
20140370595
new patent Use of synthetic scaffolds for the production of biosynthetic pathway products
The present invention provides methods of producing a product or product precursor of a biosynthetic pathway in a genetically modified host cell. The present invention also provides genetically modified host cells comprising nucleic acids encoding a scaffold polypeptide and nucleic acids comprising nucleotide sequences encoding two or more enzymes in a biosynthetic pathway.
12/18/14
20140370563
new patent Compositions and methods for the relief of inhibition of aldehyde decarbonylase
The present invention is related to compositions and methods for enhanced synthesis of hydrocarbons, particularly, but not limited to, alkanes. The invention, in one embodiment, utilizes the co-expression of a hydrogen peroxide metabolizing enzyme in the presence of an aldehyde decarbonylase enzyme to relieve hydrogen peroxide inhibition of the aldehyde decarbonylase enzyme by hydrogen peroxide.
12/18/14
20140370553
new patent Enzymes for starch processing
The present invention relates to polypeptides comprising a carbohydrate-binding module amino acid sequence and an alpha-amylase amino acid sequence as well as to the application of such polypeptides.. .
12/18/14
20140370547
new patent Expression vector organization, novel production cell generation methods and their use for the recombinant production of polypeptides
Herein is reported an expression vector comprising—an antibody light chain expression cassette,—an antibody heavy chain expression cassette, and—a selection marker expression cassette, wherein the expression cassettes are arranged unidirectional, and wherein the expression cassettes are arranged in the 5′ to 3′ sequence of antibody heavy chain expression cassette, antibody light chain expression cassette and selection marker expression cassette. Further are reported herein methods for the generation of antibody producing cells and the use of these cells for the recombinant production of antibodies..
12/18/14
20140370543
new patent Expression process
A process for the production of a target recombinant polypeptide is provided. The process comprises expressing an expression cassette encoding the target polypeptide and co-expressing an expression cassette encoding a mitochondrial foldase.
12/18/14
20140370535
new patent Sterility indicating biological compositions, articles and methods
A sterility indicating composition comprising a plurality of sterilization process resistant spores which contain an active protease during germination and initial outgrowth of the spores; and a germination medium comprising at least one labeled protease substrate and at least one nutrient for germination of the spores; wherein the medium is essentially free of a) any active protease other than the active protease contained by the plurality of spores and b) any protease substrate other than the at least one labeled protease substrate, other than any protease substrate originating from the plurality of spores, and other than any protease substrate which does not compete with the labeled protease substrate for the active protease; and wherein the at least one labeled protease substrate comprises a peptide which can be cleaved by the active protease and which is labeled with one or more dye groups, at least one of which undergoes a detectable change when the peptide is cleaved by the active protease, and wherein the labeled protease substrate is stable at least at a temperature for incubating the spores, a sterilization process indicator comprising the composition, and a method of determining the effectiveness of a sterilization process using the composition and indicator are disclosed.. .
12/18/14
20140370533
new patent Method of detecting active tb
A method of detecting active tb in a patient comprising providing at least one peptide comprising an amino acid sequence with at least 80% sequence identity to a sequence selected from seq. Id nos.
12/18/14
20140370526
new patent Detecting inclusion body myositis
Methods, devices, kits and systems for diagnosing inclusion body myositis (ibm) are provided. Methods, devices, kits and systems involves detecting the presence and/or level of autoantibodies that are reactive against at least a ˜43 kilodalton (kda) protein or ˜43 kda protein band from a muscle lysate or a mammalian cell lysate, or autoantibodies that are reactive against a cytosolic 5′-nucleotidase 1a protein (nt5c1a), or a cytosolic 5′-nucleotidase 1b protein (nt5c1b), or a nt5c1b isoform thereof, or a peptide fragment thereof, an isolated peptide thereof or a fusion protein comprising an isolated peptide of nt5c1a or nt5c1b.
12/18/14
20140370524
new patent Method for producing an examination reagent and kit for analysing a t-cell frequency
A method for producing an examination reagent includes adding a helper ligand to an unfolded receptor protein in an initial solution so as to provide a pre-solution of the examination reagent with a folded receptor protein. The folded receptor protein comprises a bonded helper ligand which can be exchanged with an examination peptide..
12/18/14
20140370514
new patent Endonucleases
The present invention provides an endonuclease i or enzymatically active fragment thereof wherein said endonuclease i has the sequence of seq id no. 4 or a sequence which is at least 70% identical thereto and wherein the amino acid residue which is immediately n-terminal of the fycgc pentapeptide motif has been substituted with a residue which is negatively charged as well as nucleic acid molecules encoding these enzymes and methods of removing contaminating polynucleotides from a sample using these enzyme..
12/18/14
20140370510
new patent Modulation of peptidome using histone deacetylase inhibitor
Provided herein is a method of modulating an apc peptidome comprising identifying an apc or an apc cell population that expresses an hdaci-associated polypeptide and administering an hdaci to the apc. Also provided herein is a method of identifying an hdaci-associated peptide comprising administering an hdaci to an apc, isolating the polypeptide from an apc mhc molecule binding cleft, and identifying the polypeptide..
12/18/14
20140370055
new patent Compositions and methods for vaccinating against hsv-2
This invention relates to therapeutic polynucleotide compositions and methods for systemic immune activation which are effective for eliciting both a systemic, non-antigen specific immune response and a strong antigen-specific immune response in mammals. The polynucleotide compositions are particularly effective for protecting mammals from herpes simplex virus (hsv), such as hsv gd2 polypeptides..
12/18/14
20140370044
new patent Modified epitopes for boosting cd4+ t-cell responses
The present invention relates to immunogenic peptides comprising a t-cell epitope. Said peptides are modified such that cd4+ t-cell responses are obtainable that are much stronger than the cd4+ t-cell responses obtained with the same peptides not comprising said modification.
12/18/14
20140370042
new patent Stabilized antiviral fusion helices
Internally cross-linked peptides useful for interfering with respiratory syncytial virus (rsv) infection is based on rsv-f protein. These peptides are capable of reducing infection in cellular and animal models..
12/18/14
20140370041
new patent Compositions and methods for treating influenza
The present application provides compositions and methods useful for treating influenza. As described herein, the compositions and methods are based on the development of peptides and peptide combinations which exhibit immunogenic properties against influenza.
12/18/14
20140370040
new patent Methods for identifying tumor-specific polypeptides
The present invention provides methods for identifying tumor-specific polypeptides, polypeptides so identified, and methods for their use.. .
12/18/14
20140370035
new patent Methods of reducing immunogenicity against factor viii in individuals undergoing factor viii therapy
The present disclosure provides methods of administering chimeric and hybrid factor viii (fviii) polypeptides comprising fviii and fc to subjects at risk of developing inhibitory fviii immune responses, including anti-fviii antibodies and/or cell-mediated immunity. The administration is sufficient to promote coagulation and to induce immune tolerance to fviii.
12/18/14
20140370032
new patent Multi-strain-reactive antibodies for therapy and diagnosis of influenza
The invention relates to a method for isolating a polypeptide reactive to influenza a hemagglutinin, comprising the steps of preparing a library of nucleic acid sequences, wherein each member of said library is attached to a polypeptide sequence encoded thereby, selecting members of said library by contacting the members with a panning antigen, wherein the panning antigen comprises a hemagglutinin stem region polypeptide sequence, subsequently removing members unreactive to the panning antigen, and selecting a member of said library by determining its binding to at least 5 influenza a hemagglutinin subtypes of subtype group 1 and 2. The invention further relates to polypeptides, particularly antibodies, obtainable by this method, that neutralize at least five influenza a subtypes of subtype group 1 and 2, to vaccines and uses thereof..
12/18/14
20140370024
new patent Methods of treating pain by inhibition of vgf activity
The present disclosure relates to a method of treating pain, in particular neuropathic pain, comprising administering a therapeutically effective amount of an inhibitor of vgf activity resulting from binding of vgf or a peptide of the type tlqp-21 to the receptor qc1qr. The disclosure also relates to and methods of screening for said inhibitors..
12/18/14
20140370023
new patent Erg monoclonal antibodies
Monoclonal antibodies, or antigen-binding fragments thereof, that bind to erg, and more specifically, to an epitope formed by amino acids 42-66 of erg3 are disclosed. The monoclonal antibodies can be non-human antibodies (e.g., rabbit or mouse) or humanized monoclonal antibodies having the cdr regions derived from those non-human antibodies.
12/18/14
20140370012
new patent Fusion proteins comprising igg2 hinge domains
The present invention relates to biologically active fusion proteins containing the igg2 hinge as a multimerization domain capable of multimerizing proteins, peptides and small molecules which are active or more active in multimeric form; compositions comprising such fusion proteins; and methods of making and using such fusion proteins.. .


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This listing is a sample listing of patent applications related to Peptide for is only meant as a recent sample of applications filed, not a comprehensive history. There may be associated servicemarks and trademarks related to these patents. Please check with patent attorney if you need further assistance or plan to use for business purposes. This patent data is also published to the public by the USPTO and available for free on their website. Note that there may be alternative spellings for Peptide with additional patents listed. Browse our RSS directory or Search for other possible listings.
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Key IP Translations - Patent Translations



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