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Peptide patents



      
           
This page is updated frequently with new Peptide-related patent applications. Subscribe to the Peptide RSS feed to automatically get the update: related Peptide RSS feeds. RSS updates for this page: Peptide RSS RSS


Date/App# patent app List of recent Peptide-related patents
10/23/14
20140317786
 Polypeptides having beta-glucosidase activity, beta-xylosidase activity, or beta-glucosidase and beta-xylosidase activity and polynucleotides encoding same patent thumbnailPolypeptides having beta-glucosidase activity, beta-xylosidase activity, or beta-glucosidase and beta-xylosidase activity and polynucleotides encoding same
The present invention relates to isolated polypeptides having beta-glucosidase activity, beta-xylosidase activity, or beta-glucosidase and beta-xylosidase activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides..
10/23/14
20140317783
 Polynucleotides, polypeptides and methods for enhancing photossimilation in plants patent thumbnailPolynucleotides, polypeptides and methods for enhancing photossimilation in plants
The present invention relates generally to the field of molecular biology and regards various polynucleotides, polypeptides and methods that may be employed to enhance yield in transgenic plants. Specifically the transgenic plants may exhibit increased yield, increased biomass or increased photoassimilation..
10/23/14
20140317781
 Isolated polynucleotides and polypeptides, transgenic plants comprising same and uses thereof in improving abiotic stress tolerance, nitrogen use efficiency, biomass, vigor or yield of plants patent thumbnailIsolated polynucleotides and polypeptides, transgenic plants comprising same and uses thereof in improving abiotic stress tolerance, nitrogen use efficiency, biomass, vigor or yield of plants
Methods of improving abiotic stress tolerance, nitrogen use efficiency, biomass, vigor or yield of a plant are provided. According to an aspect the method comprising expressing within the plant an exogenous polynucleotide having a nucleic acid sequence at least 90% identical to seq id nos: 103, 101-102, 104-216, 223-227, 264-416, wherein the nucleic acid sequence is capable of regulating abiotic stress tolerance of the plant, thereby improving abiotic stress tolerance, nitrogen use efficiency, biomass, vigor or yield of the plant.
10/23/14
20140317778
 Nucleic acid molecules encoding enzymes that confer disease resistance in jute patent thumbnailNucleic acid molecules encoding enzymes that confer disease resistance in jute
The invention further relates to vectors, host cells, seeds, and plants comprising such a nucleic acid molecule. One aspect of the invention is an isolated antibody or antigen binding fragment thereof that specifically binds to a polypeptide molecule of the present invention.
10/23/14
20140317767
 Persistent inheritance of hyperdominant traits in a perennial lineage patent thumbnailPersistent inheritance of hyperdominant traits in a perennial lineage
The present invention provides a perennial lineage engendered with hyperdominant traits that express consistent penetrance in all descendants of a founder organism. A genetic construct containing one or more genetic elements encoding a self-regulating feedback loop generates a regulatory rna, polypeptide, or other gene product at or below a trigger level of concentration in a zygote and indicates with respect to the concentration level whether one or two copies of a genetic construct conferring a hyperdominant trait exist in said zygote..
10/23/14
20140316796
 Systems, methods, and computer-readable media for limited distribution of specialty drug using a computer hub operating at a single access point patent thumbnailSystems, methods, and computer-readable media for limited distribution of specialty drug using a computer hub operating at a single access point
Embodiments of the present invention provides systems, methods, and computer-readable media for distributing a specialty drug, such as an omega conopeptide, using a computer hub that facilitates reimbursement assistance, higher expertise in handling, better care of the product, and reduced patient cost. For example, responsive to a prescription, if the patient is currently enrolled in a commercial insurance plan, a patient out-of-pocket requirement can be compared to a capped payment amount.
10/23/14
20140316122
 Hepatitis b virus vaccines patent thumbnailHepatitis b virus vaccines
This document provides methods and materials for producing immune responses against hepatitis b viruses. For example, polypeptides, nucleic acid molecules encoding such polypeptides, virus-like particles containing such polypeptides, vaccine preparations containing one or more polypeptides provided herein, vaccine preparations containing one or more nucleic acid molecules provided herein, vaccine preparations containing one or more virus-like particles provided herein, and methods for inducing immune responses against hepatitis b viruses within mammals (e.g., humans) are provided..
10/23/14
20140316112
 Method of increasing the hydrodynamic volume of polypeptides by attaching to gonadotrophin carboxy terminal peptides patent thumbnailMethod of increasing the hydrodynamic volume of polypeptides by attaching to gonadotrophin carboxy terminal peptides
This invention is directed to the use of a chorionic gonadotrophin carboxy terminal peptide (ctp) or fragments thereof for modifying a polypeptide or a fragment thereof in order to increase the hydrodynamic volume of the polypeptide or fragment thereof.. .
10/23/14
20140316109
 Activated collagen scaffold materials and their special fused active restoration factors patent thumbnailActivated collagen scaffold materials and their special fused active restoration factors
Provided are activated collagen scaffold materials as well as their special fused active restoration factors useful for promoting tissue repair, such as bone damage repair or nerve injury repair. The special fused active restoration factors are fusion proteins comprising a collagen-binding domain (cbd) at n-/c-terminus of cytokines, wherein the collagen-binding domain is a polypeptide consisting of 7-27 amino acid residues with a conservative sequence shown in seq id no:12 at n-terminus.
10/23/14
20140316107
 Cyclin based inhibitors of cdk2 and cdk4 patent thumbnailCyclin based inhibitors of cdk2 and cdk4
Structural and functional analysis of peptide inhibitor binding to the cyclin d1 groove has been investigated and used to design peptides that provide the basis for structure-activity relationships, have improved binding and have potential for development as chemical biology probes, as potential diagnostics and as therapeutics in the treatment of proliferative diseases including cancer and inflammation.. .
10/23/14
20140316106
Integrin-blocking polypeptides and uses thereof
A series of integrin blockers that present strong angiogenesis inhibiting performance, high integrin affinity and integrin-bonding capacity is provided. This series of integrin blockers can be adopted in treatment of solid tumors and rheumatoid arthritis.
10/23/14
20140315987
Cholecystokinin b receptor (cckbr) mini-promoters
Isolated polynucleotides comprising a cckbr mini-promoters are provided. The mini-promoter may be operably linked to an expressible sequence, e.g.
10/23/14
20140315953
Method and composition for treating migraines
A method for treating migraines is disclosed. The method utilizes a rapid drug delivery system which prevents deactivation or degradation of the active agent, including small molecules and peptides being administered to a patient in need of treatment.
10/23/14
20140315946
Nonpeptide hiv-1 protease inhibitors
Novel compounds and compositions for treating patients in need of relief from hiv, aids and aids-related diseases are described. Methods for treating hiv, aids, and aids-related diseases using the compounds described herein are also described..
10/23/14
20140315831
Synthesis of libraries of peptide tertiary amides
The present disclosure is directed to a novel class of peptide-like oligomers called peptide tertiary amides (ptas) and a combinatorial library of ptas along with synthetic routes for the preparation of large combinatorial libraries of these compounds. The peptide tertiary amides provide an exceptional source of high affinity and selective protein ligands that are useful as tools for biological research and as drug leads, among others..
10/23/14
20140315824
Peptide preparations and peptides with antitumour activity
The subject of the present invention are peptide preparations obtained via the enzymatic digestion of hair, wool, bristles, animal fur and individual peptides with sequences corresponding to individual components of a peptide preparation with antitumour activity, for use in the treatment of tumours or oncological prophylaxis as basal components or components of compositions of substances for treating tumours or components of substances used in oncological prophylaxis.. .
10/23/14
20140315823
Peptide compounds for suppressing inflammation
Provided herein are peptides that exhibit apoe biological activity, as well as compositions and pharmaceutical formulations that include the peptides. The peptides, compositions, and methods disclosed herein have broad applications as they can be used to treat a broad spectrum of injury, diseases, disorders, and clinical indications..
10/23/14
20140315822
High mast2-affinity polypeptides and uses thereof
The invention relates to polypeptides containing a cytoplasmic domain ending with a mast-2 binding domain, from 11 to 13 residues, the first two residues of which are s and w, and the last four residues of which are q, t, r and l, said polypeptides presenting a high affinity for the pdz domain of the human mast2 protein. The invention also relates to polynucleotides, vectors, lentiviral particles, cells as well as compositions comprising the same.
10/23/14
20140315819
Active small-molecule donkey-hide gelatin mixture and preparation method and application thereof
An active small-molecule donkey-hide gelatin mixture and a preparation method and application thereof. The active small-molecule donkey-hide gelatin mixture is prepared by using the compound protease comprising the proline protease to perform the enzymatic hydrolysis on the donkey-hide gelatin juice to which no auxiliary material is added.
10/23/14
20140315816
Albumin variants
The invention relates to variants of a parent albumin having altered plasma half-life compared with the parent albumin. The invention also relates to fusion polypeptides and conjugates comprising said variant albumin..
10/23/14
20140315813
Use of an active biological substance in abnormal cellular and viral membrane physiologies
An active biological substance is disclosed for use in abnormal cellular and viral membrane physiologies in human and mammal organisms. The active substance has diagnostic and/or therapeutic properties and contains or consists of at least one component selected from the group of substances including: histones, covalently modified histones, histone-like polypeptides, biologically active histone sequences and histone-like polypeptides as agents for stopping the supply to solid tumours over their blood vessels, for killing cells infected by virus and for killing tumour cells with disturbed lipid asymmetry..
10/23/14
20140315811
Ophthalmic preparations based on pacap (pituitary adenylate cyclase activating polypeptide) which restore the normal visual function in early glaucoma
Said preparations can be administered topically to the intact eye surface, and are useful in the treatment of various forms of retinal dystrophy/retinopathy and optic neuropathy, such as glaucoma.. .
10/23/14
20140315810
Agent for the treatment of alopecia
The solution means of the present invention is an agent for the treatment of alopecia containing as an active ingredient a c-type natriuretic peptide (cnp), a b-type natriuretic peptide (bnp), a derivative of these nps, a chimeric peptide of these nps, or a derivative of a chimeric peptide of these nps.. .
10/23/14
20140315800
Glycosylated polypeptide and drug composition containing said polypeptide
[problem] to provide a glycosylated polypeptide having affinity to somatostatin receptors and, compared to somatostatins, having improved in-blood stability. [solution] the glycosylated polypeptide is characterized by at least two amino acids in a somatostatin or an analogue thereof being replaced by glycosylated amino acids..
10/23/14
20140315793
Novel bacillus thuringiensis gene with lepidopteran activity
The invention provides nucleic acids, and variants and fragments thereof, obtained from strains of bacillus thuringiensis encoding polypeptides having pesticidal activity against insect pests, including lepidoptera. Particular embodiments of the invention provide isolated nucleic acids encoding pesticidal proteins, pesticidal compositions, dna constructs, and transformed microorganisms and plants comprising a nucleic acid of the embodiments.
10/23/14
20140315791
Method of making biologically active alpha-beta peptides
Described is a method of fabricating biologically active, unnatural polypeptides. The method includes the steps of selecting a biologically active polypeptide or biologically active fragment thereof having an amino acid sequence comprising α-amino acid residues, and fabricating a synthetic polypeptide that has an amino acid sequence that corresponds to the sequence of the biologically active polypeptide, but wherein about 14% to about 50% of the α-amino acid residues found in the biologically active polypeptide or fragment of step (a) are replaced with β-amino acid residues, and the α-amino acid residues are distributed in a repeating pattern..
10/23/14
20140315789
Antimicrobial peptides and uses thereof
The present disclosure relates generally to antimicrobial peptides, methods for their use, and methods for preparing devices having surfaces which are modified to incorporate oh said peptides. In some embodiments, the antimicrobial peptides are antimicrobial oh cationic peptides modified to comprise a thiol functional group..
10/23/14
20140315787
Antioxidant, anti-inflammatory, anti-radiation, metal chelating compounds and uses thereof
Potent compounds having combined antioxidant, anti-inflammatory, anti-radiation and metal chelating properties are described. Short peptides having these properties, and methods and uses of such short peptides in clinical and cosmetic applications are described..
10/23/14
20140315785
Methods related to the treatment of neurodegenerative and inflammatory conditions
The invention includes methods of neuroprotection, inducing release of neurotrophic factors, inhibiting the over-activation of innate immune cells, attenuating the toxin-induced death and/or damage of tissues, reducing inflammation, treating an inflammation-related condition, and inhibiting nadph oxidase, that includes contacting or administering an effective amount of at least one compound of the invention that include: valproic acid, sodium butyrate, and salts thereof; opioid peptides; a peptide comprising the tripeptide ggf; and morphinans, such as naloxone, naltrexone, 3-hydroxy-morphinan and dextromethorphan.. .
10/23/14
20140315784
Binding inhibitors of the beta. transducin repeat-containing protein
The present invention relates to compounds which bind to beta trans-ducin repeat-containing protein (ptrcp), and modulate the activity of 13trcp. In particular, the invention relates to compounds which demonstrate optimised binding to ptrcp.
10/23/14
20140315758
Cancer antigen-specific t-cell receptor gene, peptide encoded by the gene, and use of them
Disclosed are: a nucleotide sequence and an amino acid sequence for cdr3 region of t-cell receptor (tcr) gene of wt1-specific cytotoxic t-cell (ctl) for wt1 protein; a method for the detection or treatment of cancer using the nucleotide sequence or the amino acid sequence; and a chip, a primer set, a kit, an apparatus and the like for use in the detection of cancer, each of which comprises the nucleotide sequence or the amino acid sequence.. .
10/23/14
20140315751
High throughput selection of specific cell binding and lytic polypeptides
The invention provides methods for identifying cell binding and/or lytic polypeptides that permit production of specific polypeptide therapeutics in a high throughput manner.. .
10/23/14
20140315744
Assessment of oocyte competence by detecting spsb2 and/or tp53i3 gene expression
Methods are provided for evaluating an oocyte for fertilization and implantation comprising analysis of gene expression in cumulus cells wherein the detected genes or polypeptides include at least spsb2 and tp53i3. For example, methods are provided for determining whether a cumulus cell expresses, or does not express, one or more of a group of markers identified as differently expressed between cumulus cells associated with chromosomally normal oocytes and cumulus cells associated with chromosomally abnormal oocytes.
10/23/14
20140315741
Methods and materials for modulating deubiquitinases and ubiquitinated polypeptides
This document relates to methods and materials involved in modulating deubiquitinases (e.g., usp10 polypeptides) and/or ubiquitinated polypeptides (e.g., tumor suppressor polypeptides or mutant versions of tumor suppressor polypeptides). For example, methods and materials for increasing deubiquitinase (e.g., a usp10 polypeptide) expression or activity, methods and materials for decreasing deubiquitinase (e.g., a usp10 polypeptide) expression or activity, methods and materials for stabilizing tumor suppressor polypeptides (e.g., wild-type p53 polypeptides), methods and materials for de-stabilizing mutant versions of tumor suppressor polypeptides (e.g., mutant p53 polypeptides), and methods and materials for reducing cancer cell proliferation, increasing cancer cell apoptosis, and/or treating cancer (e.g., cancers having reduced levels of wild-type p53 polypeptides or cancers having increased levels of mutant p53 polypeptides) are provided.
10/23/14
20140315740
Antigen array and diagnostic uses thereof
A method of diagnosing an immune disease, or a predisposition thereto, in a subject is disclosed. The method comprises determining a capacity of immunoglobulins of the subject to specifically bind each antigen probe of an antigen probe set, wherein the antigen probe set comprises a plurality of antigen probes selected from the group consisting of at least a portion of a cell/tissue structure molecule, at least a portion of a heat shock protein, at least a portion of an immune system molecule, at least a portion of a homopolymeric polypeptide, at least a portion of a hormone, at least a portion of a metabolic enzyme, at least a portion of a microbial antigen, at least a portion of a molluscan antigen, at least a portion of a nucleic acid, at least a portion of a plant antigen, at least a portion of plasma molecule, and at least a portion of a tissue antigen, wherein the capacity is indicative of the immune disease or the predisposition thereto, thereby diagnosing the immune disease, or the predisposition thereto, in the subject..
10/23/14
20140315735
Cancer antigen-specific t-cell receptor gene, peptide encoded by the gene, and use of them
Disclosed are: a nucleotide sequence and an amino acid sequence for cdr3 region of t-cell receptor (tcr) gene of wt1-specific cytotoxic t-cell (ctl) for wt1 protein; a method for the detection or treatment of cancer using the nucleotide sequence or the amino acid sequence; and a chip, a primer set, a kit, an apparatus and the like for use in the detection of cancer, each of which comprises the nucleotide sequence or the amino acid sequence.. .
10/23/14
20140315734
Methods and compositions for assigning likelihood of acute kidney injury progression
The invention encompasses diagnosis and prognosis in the context of heart or renal failure, particularly in subjects who exhibit a normal body fluid level of a natriuretic peptide. The invention also relates to methods of assigning an increased likelihood that a subject having aki is susceptible to aki progression.
10/23/14
20140315278
Spore surface displays of bioactive molecules
This invention discloses novel bacterial spore systems. Genetically modified or genetically engineered viable spore systems expressing bioactive polypeptides, for example bacteriocins and/or enzymatically active feed enzymes, at the spore surface, have a great potential use in animal feeding.
10/23/14
20140315276
Synthesis of linear and branched polymers of polypeptides through direct conjugation
Methods are provided for a one step synthesis of polypeptide polymers or co-polymers. The polymers or co-polymers can be linear or branched.
10/23/14
20140315275
Isoprene synthase variants with improved solubility for production of isoprene
The present invention provides methods and compositions of variant polypeptides having isoprene synthase activity with improved solubility. In particular, the present invention provides isoprene synthase variant for increased isoprene production in recombinant host cells..
10/23/14
20140315274
Methods for production of archeae protease in yeast
The invention relates to: a method for producing a protease in yeast, comprising providing a yeast host cell comprising at least one polynucleotide expression construct encoding a first polypeptide secreted by the host cell in translational fusion with a second polypeptide, wherein the second polypeptide is a protease having a mature amino acid sequence similar to that of seq id no:2; the corresponding yeast host cell and the expression construct.. .
10/23/14
20140315253
Activated collagen scaffold materials and their special fused active restoration factors
Provided are activated collagen scaffold materials as well as their special fused active restoration factors useful for promoting tissue repair, such as bone damage repair or nerve injury repair. The special fused active restoration factors are fusion proteins comprising a collagen-binding domain (cbd) at n-/c-terminus of cytokines, wherein the collagen-binding domain is a polypeptide consisting of 7-27 amino acid residues with a conservative sequence shown in seq id no:4 at n-terminus.
10/23/14
20140315247
Expression cassette, use of the expression cassette, expression vector, prokaryotic host cell comprising expression vector, bacterial strain and a method for producing a polypeptide
The subject matters of invention relate to expression cassette, use of the expression cassette, expression vector, prokaryotic host cell harbouring expression vector, bacterial strain, and method for producing a polypeptide. In more detail, the invention relate to stable expression of recombinant polypeptides, in systems with no need of using antibiotics.
10/23/14
20140315231
Quantification of transthyretin and its isoforms
The present invention relates to assays and methods for the detection of transthyretin and its isoforms. Specifically, the assays and methods of the present invention embrace liquid chromatography and mass spectrometry.
10/23/14
20140315204
Immunohistochemistry detection method
The invention provides compositions and methods for the detection of targets in a sample; in particular, an immunohistochemistry (ihc) sample. Probes and detectable labels may be provided in multiple layers in order to increase the flexibility of a detection system, and to allow for amplification to enhance the signal from a target.


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This listing is a sample listing of patent applications related to Peptide for is only meant as a recent sample of applications filed, not a comprehensive history. There may be associated servicemarks and trademarks related to these patents. Please check with patent attorney if you need further assistance or plan to use for business purposes. This patent data is also published to the public by the USPTO and available for free on their website. Note that there may be alternative spellings for Peptide with additional patents listed. Browse our RSS directory or Search for other possible listings.
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