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Peptide patents



      
           
This page is updated frequently with new Peptide-related patent applications. Subscribe to the Peptide RSS feed to automatically get the update: related Peptide RSS feeds. RSS updates for this page: Peptide RSS RSS


Date/App# patent app List of recent Peptide-related patents
01/29/15
20150033412
 Plants having enhanced yield-related traits and a  making the same patent thumbnailnew patent Plants having enhanced yield-related traits and a making the same
The present invention relates generally to the field of molecular biology and concerns a method for enhancing plant yield-related traits relative to control plants. More specifically, the present invention concerns a method for enhancing yield related traits in plants relative to control plants, by modulating, preferably increasing, expression in the roots of a plant, of a nucleic acid sequence encoding a 2-cysteine peroxiredoxin (2-cys prx); or by modulating expression of a nucleic acid encoding an ann polypeptide in a plant.
Crop Functional Genomics Center
01/29/15
20150033411
 Genetically modified plants having improved saccharification properties patent thumbnailnew patent Genetically modified plants having improved saccharification properties
The invention relates to methods for increasing saccharification potential in a plant, comprising overexpressing a polynucleotide encoding an acetyl xylan esterase polypeptide in at least one cell type in said plant. The invention further relates to methods for producing genetically modified plants overexpressing a polynucleotide encoding an acetyl xylan esterase polypeptide, as well as to genetically modified plants produced by such methods..
Swe Tree Technologies Ab
01/29/15
20150033408
 Polypeptide involved in morphogenesis and/or environmental stress resistance of plant patent thumbnailnew patent Polypeptide involved in morphogenesis and/or environmental stress resistance of plant
Provided is a plant having a desired phenotype and/or desired stress resistance. Provided is a transgenic plant overexpressing a polypeptide that has the activity to control plant morphology or the activity to enhance the environmental stress resistance of plants, wherein the polypeptide(s) is one polypeptide or are a plurality of polypeptides selected from among polypeptides comprising the amino acid sequences represented by seq id nos: 1-317..
Riken
01/29/15
20150033389
 Plants having improved growth properties patent thumbnailnew patent Plants having improved growth properties
The invention relates to a method for producing a genetically modified plant with improved growth properties as compared to a corresponding non-genetically modified wild type plant, said method comprising reducing or deleting the amount or activity of an ebi1 or ebi2 polypeptide in a plant cell, a plant or a part thereof.. .
Swetree Technologies Ab
01/29/15
20150031868
 Diterpene production patent thumbnailnew patent Diterpene production
The present invention relates to a recombinant microorganism comprising one or more nucleotide sequence(s) encoding: a polypeptide having ent-copalyl pyrophosphate synthase activity; a polypeptide having ent-kaurene synthase activity; a polypeptide having ent-kaurene oxidase activity; and a polypeptide having kaurenoic acid 13-hydroxylase activity, whereby expression of the nucleotide sequence(s) confer(s) on the microorganism the ability to produce at least steviol. The recombinant microorganism may also be capable of expressing one or more udp-glucosyltransferases such that the microorganism is capable of producing one or more steviol glycosides..
Dsm Ip Assets B.v.
01/29/15
20150031864
 Modified adiponectin polypeptides and their uses patent thumbnailnew patent Modified adiponectin polypeptides and their uses
Modified adiponectin polypeptides and uses thereof are provided.. .
Ambrx, Inc.
01/29/15
20150031862
 Optimized fc variants patent thumbnailnew patent Optimized fc variants
The present invention relates to fc variants having decreased affinity for fcγriib, methods for their generation, fc polypeptides comprising optimized fc variants, and methods for using optimized fc variants.. .
Xencor, Inc.
01/29/15
20150031855
 Methods for enhancing bacterial cell display of proteins and peptides patent thumbnailnew patent Methods for enhancing bacterial cell display of proteins and peptides
Methods of making and using bacterial display polypeptide libraries using circularly permuted ompx (cpx) variants are disclosed. The invention further relates to methods for enhancing the display of proteins and peptides at the surface of bacteria by optimizing linkers and incorporating mutations at positions 165 and 166 of cpx..
01/29/15
20150031851
 Hmgn2 peptides and related molecules that selectively home to tumor blood vessels and tumor cells patent thumbnailnew patent Hmgn2 peptides and related molecules that selectively home to tumor blood vessels and tumor cells
The present invention provides a conjugate which contains a therapeutic moiety linked to a homing molecule that selectively homes to tumor blood vessels and tumor cells and that specifically binds the receptor bound by peptide kdepqrrsarlsakpappkpepkpkkapakk (seq id no: 9). Methods of directing a conjugate of the invention to tumor blood vessels and tumor cells and of using a conjugate to treat cancer also are provided..
Sanford-bumham Medical Research Institute
01/29/15
20150031756
 Lentiviral vectors and uses thereof patent thumbnailnew patent Lentiviral vectors and uses thereof
The invention relates to compositions containing polynucleotide vectors capable of expressing a nucleic acid encoding a fusion polypeptide on the surface of a viral particle and/or a eukaryotic cell.. .
Dana-farber Cancer Institute
01/29/15
20150031748
new patent

Modulating the interaction between zo-2/tjp2 and a snail zinc finger transcription factor family member


There is provided a method of identifying candidate agents capable of modulating interaction between a first polypeptide and a second polypeptide, wherein the first polypeptide is zo-2/tjp2 or a functional variant thereof and the second polypeptide is a snail zinc finger transcription factor family member or a functional variant thereof.. .
Agency For Science, Technology And Research
01/29/15
20150031715
new patent

Integrin antagonist conjugates for targeted delivery to cells expressing vla-4


The invention relates to compounds of formula i: wherein r1, r2, and n are defined in the detailed description and claims. In particular, the present invention relates to the compounds of formula i for use in the manufacture and delivery of conjugated moieties such as small molecules, peptides, nucleic acids, fluorescent moieties, and polymers which are linked to vla-4 integrin antagonists to target cells expressing vla-4..
Hoffmann-la Roche Inc.
01/29/15
20150031703
new patent

Novel fgfr3 fusion


[means for solution] the method detects a fusion gene composed of a portion of an fgfr3 gene and a portion of a tacc3 gene or a fusion protein encoded by the fusion gene. The primer set, the probe set, or the detection kit comprises a sense primer and a probe set designed from the portion encoding fgfr3 and an antisense primer and a probe set designed from the portion encoding tacc3.
01/29/15
20150031637
new patent

Pharmaceutical combination comprising an ibat inhibitor and a bile acid binder


The present invention relates to a combination comprising a substance with inhibiting effect on the ileal bile acid transport system (ibat) and at least one other active substance selected from an ibat inhibitor; an enteroendocrine peptide or enhancer thereof; a dipeptidyl peptidase-iv inhibitor; a biguanidine; an incretin mimetic; a thiazolidinone; a ppar agonist; a hmg co-a reductase inhibitor; a bile acid binder; and a tgr5 receptor modulator; wherein the ibat inhibitor compound and the at least one other active substance are administered simultaneously, sequentially or separately.. .
Albireo Ab
01/29/15
20150031634
new patent

Angiotensin peptides in treating marfan syndrome and related disorders


The present invention provides, among other things, methods of treating marfan syndrome and/or a marfan-related disorder including administering to a subject suffering from or susceptible to marfan syndrome and/or a marfan-related disorder an angiotensin (1-7) peptide. In some embodiments, the angiotensin (1-7) peptide is administered at an effective dose periodically at an administration interval such that at least one symptom or feature of marfan syndrome and/or a marfan-related disorder is reduced in intensity, severity, duration, or frequency or has delayed in onset..
Tarix Pharmaceuticals Ltd
01/29/15
20150031633
new patent

Bifunctional peptide


The bifunctional peptide is capable of activating collagen synthesis and inhibiting the production of matrix metallo-proteinases. The peptide has a sequence including three peptide parts a, b and c.
Centre National De La Recherche Scientifique
01/29/15
20150031630
new patent

Peptide pharmaceuticals


Described herein are methods of syntheses and therapeutic uses of covalently modified peptides and/or proteins. The covalently modified peptides and/or proteins allow for improved pharmaceutical properties of peptide and protein-based therapeutics..
Eumederis Pharmaceuticals, Inc.
01/29/15
20150031626
new patent

Adam22 for use as a prognostic variable, and target for therapy, of a metastatic breast cancer disease


A method of diagnosing metastatic potential of a breast cancer in an individual with breast cancer is described. The method comprises a step of assaying a breast cancer tumour sample from the patient for expression of adam22, wherein expression of adam22 correlates with increased potential for metastasis compared with a patient who is adam22 negative.
Royal College Of Surgeons In Ireland
01/29/15
20150031618
new patent

Muteins of a1m lipocalin and production therefor


The present disclosure relates to a collection of novel muteins derived from human α1m (or a1m) polypeptide or a functional homologue thereof. The disclosure further refers to a α1m mutein capable of specifically binding to one or more targets other than a target to which wild-type α1m binds.
Technische Universitaet Muenchen
01/29/15
20150031615
new patent

Growth hormone releasing peptides


And pharmaceutical compositions and methods of use thereof.. .
01/29/15
20150031612
new patent

Allosteric modulators of egfr and constitutively active mutants


The present invention includes a novel class of allosteric modulators that target a protein having a juxtamembrane segment. In another embodiment, the allosteric modulator is a peptide mimetic that is capable of interacting with an α-helix or a coiled coil domain of a protein.
Yale University
01/29/15
20150031610
new patent

Derivatized polyglucosamines for delivery of small molecules, peptides, and proteins


Described herein are compositions comprising a derivatized polyglucosamine and a small molecule, peptide, or protein and related methods of use, e.g., to deliver a small molecule, peptide, or protein to cells (e.g., cancer cells) or tissues (e.g., mucosal membrane and epithelial membrane), e.g., to treat a disease or condition in a subject.. .
Synedgen, Inc.
01/29/15
20150031609
new patent

Methods and compositions for delivering peptides


Methods are provided for purifying peptides and proteins by incorporating the peptide or protein into a diketopiperazine or competitive complexing agent to facilitate removal one or more impurities, from the peptide or protein. Formulations and methods also are provided for the improved transport of active agents across biological membranes, resulting for example in a rapid increase in blood agent concentration.
Mannkind Corporation
01/29/15
20150031604
new patent

Cyclic polypeptides for the treatment of heart failure


Or an amide, an ester or a salt thereof, or a bioconjugate thereof, wherein x1, x3, x4, x7, x8, x9, x10, x11, x12 and x13 are defined herein. The polypeptides are agonist of the apj receptor.
01/29/15
20150031601
new patent

Antimicrobial peptide variants and polynucleotides encoding same


The present invention relates to variants of a parent antimicrobial peptide. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants..
Addenium Biotech Aps
01/29/15
20150031600
new patent

Designed biosurfactants, their manufacture, purification and use


The present invention relates to designed polypeptide biosurfactants that may be prepared by recombinant technology in commercially useful amounts and purified by simple non-chromatographic methods. The designed polypeptide biosurfactants comprise at least one stimuli-responsive amino acid residue or at least one glutamine or asparagine residue and may be useful in modulating the stability of a foam, alone or in combination with an α-helical peptide.
The University Of Queensland
01/29/15
20150031583
new patent

Phage display system


A phage display system is provided comprising a mutant phage-infected host cell adapted to express a peptide of interest fused to a phage capsid protein, wherein the mutant phage includes a nonsense mutation which prevents expression of the capsid protein as a functional protein, and wherein expression of the peptide of interest is controlled by an inducible repressor and by a suppressor that suppresses the nonsense mutation.. .
01/29/15
20150031566
new patent

Biotinylated mhc complexes and their uses


The invention demonstrates an improved choice of biotinylation peptide to be used in a combination or fusion with an mhc molecule for immobilizing or multimerising such mhc molecules for a variety of purposes.. .
Proimmune Limited
01/29/15
20150031564
new patent

Ligand having three finger structure and a detecting a molecule by using thereof


The present invention improves in vitro virus synthesis efficiency and stability of mrna derived from screened cdna in a cdna display method to improve the efficiency and reliability of the production of a peptide by a molecular evolutionary engineering technique. Provided is a ligand which comprises three fingers formed from antiparallel β-sheets and a loop region intercalated between the antiparallel β-sheets, wherein at least a fingertip part formed by the loop region of each of the fingers is bound to the target molecule, and wherein the ligand comprises the amino acid sequence of seq id no: 1.
Nikon Corporation
01/29/15
20150031563
new patent

Multi component antibody based detection technology


The disclosure provides methods for detecting the concurrent presence of at least two targets within a biological sample. The method includes contacting said biological sample with a first binding agent, said first binding agent operably linked to a first sortase molecule, wherein said first binding agent specifically binds to a first target; contacting said biological sample with a second binding agent, said second binding agent operably linked to a first sortase recognition sequence peptide, wherein said second binding agent specifically binds to a second target; adding a sortase substrate under conditions where a first sortase-mediated ligation of the sortase substrate to the first sortase recognition sequence will produce a ligation product, and detecting the ligation product, wherein detection of said ligation product indicates the concurrent presence of the first target and the second target in the biological sample.
01/29/15
20150031128
new patent

Culture medium for eukaryotic cells


The invention pertains to the use of (i) one or more c2-c6 alpha-hydroxy acids, salts of these acids, esters of these acids and combinations thereof; and (ii) one or more compounds selected from—the group of amino acid derivatives consisting of γ-glutamyl amino acids, pyroglutamyl amino acids, glutamate-containing or proline-containing dipeptides, oxo-aminoacids, homo-amino acids, n-acetyl amino-acids and glycyl-glycine; -phenolic acid derivatives; -linear c2-c6 or cyclic c6 sugar alcohols; -pyridinic acid derivatives; and -nucleobases and/or nucleotides chosen from uracil, adenine, adenosine 3′-monophosphate (3′-amp) and adenosine 5′-monophosphate (amp), as a growth-and production promoting ingredient, in culture media for culturing eukaryotic cells. The invention further pertains to culture media containing these components at levels of at least 0.001 mg/l..
Friesland Brands B.v.
01/29/15
20150031116
new patent

Integrated active flux microfluidic devices and methods


The invention relates to a microfabricated device for the rapid detection of dna, proteins or other molecules associated with a particular disease. The devices and methods of the invention can be used for the simultaneous diagnosis of multiple diseases by detecting molecules (e.g.
California Institute Of Technology
01/29/15
20150031115
new patent

Expression in insect cells of genes with overlapping open reading frames, methods and compositions therefor


The present teachings disclose nucleic acid cassettes for expressing in an insect cell a plurality of polypeptides encoded by a gene comprising overlapping open reading frames (orfs). A cassette comprises, in 5′ to 3′ order, a) a first insect cell-operable promoter, b) a 5′ portion of a gene comprising a first orf of the gene, c) an intron comprising a second insect cell-operable promoter, and d) a 3′ portion of the gene comprising at least one additional orf.
Virovek, Inc.
01/29/15
20150031113
new patent

Polypeptides having endoglucanase activity and polynucleotides encoding same


Provided are isolated polypeptides having endoglucanase activity, catalytic domains, cellulose binding domains and polynucleotides encoding the polypeptides, catalytic domains or cellulose binding domains. Also provided are nucleic acid constructs, vectors and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides catalytic domains or cellulose binding domains..
Novozymes A/s
01/29/15
20150031111
new patent

Lipase variants and polynucleotides encoding same


The present invention relates to isolated lipase variants, comprising a substitution at one or more positions corresponding to positions i86d,e,n,q, e87c, i90d,e,q, and n92d,e,q of the mature polypeptide of seq id no: 2, wherein the variant has lipase activity. In some embodiments the present invention relates to isolated polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; methods of producing the variants; and compositions comprising the variants.
Novozymes A/s
01/29/15
20150031108
new patent

Processes for preparing peptide conjugates and linkers


The present invention provides a process for preparing a compound of formula 5b, as well as intermediates thereof, and novel classes of compounds useful in process for preparing these and similar compounds.. .
Pfizer Inc.
01/29/15
20150031102
new patent

Methods and compositions for enhanced production of butanol by clostridia


The invention relates generally to methods and compositions for maintaining and manipulating microbial cultures of gram-positive bacteria. Also provided are methods for identifying quorum sensing regulatory proteins and auto-inducing peptides in gram-positive bacteria.
Butrolix Llc
01/29/15
20150031096
new patent

Multizymes and their use in making polyunsaturated fatty acids


Isolated nucleic acid fragments and recombinant constructs comprising such fragments encoding multizymes (i.e., single polypeptides having at least two independent and separable enzymatic activities) along with a method of making long-chain polyunsaturated fatty acids (pufas) using these multizymes in plants and oleaginous yeast are disclosed.. .
E I Du Pont De Nemours And Company
01/29/15
20150031095
new patent

Enone reductases


The disclosure relates to engineered enone reductase polypeptides having improved properties, polynucleotides encoding the engineered polypeptides, related vectors, host cells, and methods for making the engineered enone reductase polypeptides. The disclosure also provides methods of using the engineered enone reductase polypeptides for chemical transformations..
Codexis, Inc.
01/29/15
20150031094
new patent

Polynucleotides encoding engineered ketoreductase polypeptides


The present disclosure provides engineered ketoreductase enzymes having improved properties as compared to a naturally occurring wild-type ketoreductase enzyme. Also provided are polynucleotides encoding the engineered ketoreductase enzymes, host cells capable of expressing the engineered ketoreductase enzymes, and methods of using the engineered ketoreductase enzymes to synthesize a variety of chiral compounds.
Codexis, Inc.
01/29/15
20150031091
new patent

Polypeptides having alpha-amylase activity and polynucleotides encoding same


The present invention provides isolated polypeptides having alpha-amylase activity catalytic domains, carbohydrate binding domains and polynucleotide encoding the polypeptides, catalytic domains or carbohydrate binding domains. The invention also provides nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides, catalytic domains or carbohydrate binding domains..
Novozymes A/s
01/29/15
20150031082
new patent

Polypeptides having beta-glucosidase activity, beta-xylosidase activity, or beta-glucosidase activity and beta-xylosidase activity and polynucleotides encoding same


The present invention relates to isolated polypeptides having beta-glucosidase activity, beta-xylosidase activity, or beta-glucosidase and beta-xylosidase activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides..
Novozymes A/s
01/29/15
20150031079
new patent

Polypeptides having xylanase activity and polynucleotides encoding same


The present invention relates to isolated polypeptides having xylanase activity and polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides..
Novozymes Inc.
01/29/15
20150031063
new patent

Method of detecting at least one mechanism of resistance to carbapenems by mass spectrometry


The present invention pertains to a method of detection, by mass spectrometry, of at least one marker of at least one mechanism of resistance to at least one antimicrobial, resistance of at least one microorganism contained in a sample, characterised in that the antimicrobial is a carbapenem, and said resistance markers are proteins or peptides. Preferably, said proteins or peptides are proteins from said microorganism..
Biomerieux, Inc.
01/29/15
20150031060
new patent

Fad-conjugated glucose dehydrogenase gene


Disclosed herein are a gene (polynucleotide) encoding an fad-conjugated glucose dehydrogenase which can be characterized by reactivity to glucose, thermal stability, substrate-recognition performance, and low activity for maltose; a process for the production of the enzyme using a transformant cell transfected with the gene; a method for the determination of glucose; a reagent composition for use in the determination of glucose; and a biosensor for use in the determination of glucose. An embodiment is a polynucleotide encoding an fad-conjugated glucose dehydrogenase, comprising a polypeptide whose amino acid sequence comprises x1-x2-x3-x4-x5-x6, wherein x1 and x2 independently represent an aliphatic amino acid residue; x3 and x6 independently represent a branched amino acid residue; and x4 and x5 independently represent a heterocyclic amino acid residue or an aromatic amino acid residue..
Ikeda Food Research Co., Ltd.
01/29/15
20150031059
new patent

Novel glucose dehydrogenase


An object of the present invention is to provide a novel glucose dehydrogenase, a method for producing the glucose dehydrogenase, and applications of the glucose dehydrogenase. The flavin-binding glucose dehydrogenase of the invention has the following characteristics (1) and (4): (1) molecular weight: the molecular weight of a polypeptide moiety in the enzyme is about 68 kda as measured by sds-polyacrylamide electrophoresis; (2) km value: the km value for d-glucose is about 15 mm or less; (3) temperature stability: stable at a temperature of 55° c.
Toyobo Co., Ltd.
01/29/15
20150031056
new patent

Development of specific immunoassay critical reagents for pharmacokinetic assessments of peptide polymers in preclinical and clinical matrices


The present disclosure provides methods of developing a specific immunoassay for the pharmacokinetic assessments of peptides, peptide oligomer and polymer including glatiramer acetate (ga), also known as copolymer 1, copolymer-1, cop 1 or cop in the clinical and preclinical matrices.. .
01/29/15
20150031054
new patent

Method and system for diagnosing alzheimer's disease


Disclosed herein is a method for diagnosing alzheimer's disease capable of minimizing invasiveness to reduce the risk of infection. The method for diagnosing alzheimer's disease includes the steps of: pretreating an intranasal specimen; detecting tau protein or amyloid beta peptide (aβ) in the pretreated intranasal specimen; comparing a value of the tau protein or the aβ obtained in the detection step with a predetermined value; and displaying a comparison result obtained in the comparison step..
Shiga University Of Medical Science
01/29/15
20150031025
new patent

Genetic products differentially expressed in tumors and use thereof


The invention relates to the identification of genetic products that are expressed in association with a tumor and the nucleic acid coding therefor. The invention relates to the therapy and diagnosis of diseases in which said genetic products that are expressed in association with a tumor are expressed in aberrant manner.
Ganymed Pharmaceuticals Ag


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This listing is a sample listing of patent applications related to Peptide for is only meant as a recent sample of applications filed, not a comprehensive history. There may be associated servicemarks and trademarks related to these patents. Please check with patent attorney if you need further assistance or plan to use for business purposes. This patent data is also published to the public by the USPTO and available for free on their website. Note that there may be alternative spellings for Peptide with additional patents listed. Browse our RSS directory or Search for other possible listings.
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