Follow us on Twitter
twitter icon@FreshPatents


Peptide patents

      

This page is updated frequently with new Peptide-related patent applications.




 Mass spectrometry  polypeptides patent thumbnailnew patent Mass spectrometry polypeptides
Provided is a method for measuring a target polypeptide in a biological sample abundantly containing impurities by mass spectrometry. A method for measuring a target polypeptide in a biological sample includes: a first reaction step of bringing a liquid containing a biological sample into contact with a first antibody-immobilizing carrier to bind the target polypeptide in the biological sample with the first carrier; a first washing step of washing the first carrier; a first eluting step of eluting the target polypeptide from the first carrier by using an acidic solution to obtain a first eluate; a neutralizing step of obtaining a first purified solution by adding a neutral buffer to the first eluate; a second reaction step of bringing the first purified solution into contact with a second antibody-immobilizing carrier, to bind the target polypeptide in the first purified solution with the second carrier; a second washing step of washing the second carrier; a second eluting step of eluting the target polypeptide from the second carrier by using an acidic solution to obtain a second purified solution; and a step of detecting the target polypeptide in the second purified solution by mass spectrometry..
Shimadzu Corporation


 Targeting of chondroitin sulfate glycans patent thumbnailnew patent Targeting of chondroitin sulfate glycans
The present invention relates to functional binding fragments comprising the minimal binding fragments of var2csa, to antibodies against such binding fragments of var2csa, nucleic acids encoding such fragments of var2csa as well as methods for their production. The invention further relates to conjugates and fusion proteins of var2csa polypeptides including the minimal binding fragments and their use, in particular in the treatment of conditions associated with expression of chondroitin sulfate a (csa), such as an inappropriate expression of chondroitin sulfate a (csa)..
Var2 Pharmaceutical Aps


 Molecular sensor preparations and uses thereof patent thumbnailnew patent Molecular sensor preparations and uses thereof
The present invention relates to a method of preparing a molecular sensor that is specific for a target molecule having a saccharide or peptide region. The method comprises using the target molecule as a template and incubating the template with a receptor to form a template-receptor complex.
The University Of Birmingham


 Localized surface plasmon resonance sensing of human performance biomarkers using short peptide recognition elements on optically active metal nanostructures patent thumbnailnew patent Localized surface plasmon resonance sensing of human performance biomarkers using short peptide recognition elements on optically active metal nanostructures
A biomarker sensor using short peptide recognition elements. The biomarker sensor includes a substrate and a metallic layer on a surface of that substrate that is localized surface plasmon resonance reactive.
Government Of The United States As Represented By The Secretary Of The Air Force


 Binding fusion proteins, binding fusion protein-drug conjugates, xten-drug conjugates and methods of making and using same patent thumbnailnew patent Binding fusion proteins, binding fusion protein-drug conjugates, xten-drug conjugates and methods of making and using same
The present invention relates to binding fusion protein compositions comprising targeting moieties linked to extended recombinant polypeptide (xten), binding fusion protein-drug conjugate compositions, and xten-drug conjugate compositions, isolated nucleic acids encoding the compositions and vectors and host cells containing the same, and methods of using such compositions in treatment of diseases, disorders, and conditions.. .
Amunix Operating Inc.


 Novel dna-binding proteins and uses thereof patent thumbnailnew patent Novel dna-binding proteins and uses thereof
Disclosed herein are polypeptides, polynucleotides encoding, cells and organisms comprising novel dna-binding domains, including tale dna-binding domains. Also disclosed are methods of using these novel dna-binding domains for modulation of gene expression and/or genomic editing of endogenous cellular sequences..
Sangamo Biosciences, Inc.


 Method for generating t-cells compatible for allogenic transplantation patent thumbnailnew patent Method for generating t-cells compatible for allogenic transplantation
The present invention pertains to engineered t-cells, method for their preparation and their use as medicament, particularly for immunotherapy. The engineered t-cells of the invention are characterized in that the expression of beta 2-microglobulin (b2m) and/or class ii major histocompatibility complex transactivator (ciita) is inhibited, e.g., by using rare-cutting endonucleases able to selectively inactivating by dna cleavage the gene encoding b2m and/or ciita, or by using nucleic acid molecules which inhibit the expression of b2m and/or ciita.
Cellectis


 Hppd variants and methods of use patent thumbnailnew patent Hppd variants and methods of use
In particular, isolated polynucleotides encoding hppd inhibitor tolerance polypeptides are provided. Additionally, amino acid sequences corresponding to the polynucleotides are encompassed..

 Method for the production of multiple-unsaturated fatty acids in transgenic organisms patent thumbnailnew patent Method for the production of multiple-unsaturated fatty acids in transgenic organisms
The present invention relates to a process for the production of polyunsaturated fatty acids in an organism by introducing, into the organism, nucleic acids which encode polypeptides with Δ5-elongase activity. Advantageously, these nucleic acids can be expressed in the organism together with further nucleic acids which encode polypeptides of the biosynthesis of the fatty acid or lipid metabolism.
Basf Plant Science Gmbh


 Novel use of a dense and erect panicle 1 gene in improving nitrogen utilization efficiency patent thumbnailnew patent Novel use of a dense and erect panicle 1 gene in improving nitrogen utilization efficiency
The present invention provides methods of increasing nitrogen utilization efficiency (nue) in a transgenic plant comprising the introduction of a nucleic acid encoding a dep1 polypeptide into a plant to produce a transgenic plant that expresses the nucleic acid to produce the dep1 polypeptide, thereby resulting in an increased nue as compared with a control plant. Also provided are methods of increasing nue in a plant comprising reducing the amount and/or activity of a dep1 polypeptide..
Institute Of Genetics And Developmental Biology, Chinese Academy Of Sciences


new patent

Method for high efficiency protein delivery into plastids

The present invention provides a recombinant dna molecule encoding a fusion protein, comprising a first dna sequence encoding a high-efficiency transit peptide operably linked to a second dna sequence encoding a passenger protein, wherein the high-efficiency transit peptide is selected from the group consisting of transit peptides of the precursors of translocon at the inner envelope membrane of chloroplasts 40 kd (prtic40), chaperonin 10-2 (prcpn10-2), fibrillin 1b (prfibrillin), atp sulfurylase 1 (praps1), atp sulfurylase 3 (praps3), 5′-adenylylsulfate reductase 3 (prapr3), stromal ascorbate peroxidase (prsapx), prtic40-e2a (a prtic40 variant), prcpn10-1-Δc7c37s (a chaperonin 10-1 variant), a functional fragment of any of the transit peptides and an equivalent thereof. And the present invention also provides a method of high efficiency delivery of a protein into plastids using the high-efficiency transit peptides..
Academia Sinica

new patent

Generation of acyl amino acids

Engineered polypeptides useful in synthesizing acyl amino acids are provided. Also provided are methods of making acyl amino acids using engineered polypeptides.
Modular Genetics, Inc.

new patent

Ddx5 and associated non-coding rnas and modulation of th17 effector function

Methods for screening to identify agents capable of modulating ddx5 polypeptide activity are encompassed herein as are methods for using such agents to treat subjects afflicted with th17-mediated inflammatory conditions and autoimmune diseases including, without limitation, crohn's disease, ulcerative colitis, multiple sclerosis, rheumatoid arthritis, and psoriasis and methods for using such agents to treat subjects afflicted with cancer.. .

new patent

Hybrid polymers, pharmaceutical compositions and methods of synthesizing the same

Wherein abiotic oligomer, polypeptide, x, y, and r1 are as described herein. The methods to prepare the hybrid polymers via novel oxazolidinyl compounds are also described..

new patent

Modified caspase polypeptides and uses thereof

The technology relates in part to compositions comprising modified caspase-9 polypeptides, compositions comprising nucleic acids coding for modified caspase-9 polypeptides, chimeric modified caspase-9 polypeptides, and methods of use thereof, including methods for cell therapy. Methods for cell therapy include modifying transfused cells to express an inducible modified caspase-9 protein, with reduced basal activity in the absence of the inducer..
Bellicum Pharmaceuticals, Inc.

new patent

Methods for producing multiple recombinant polypeptides in a filamentous fungal host cell

The present invention relates to methods for constructing a filamentous fungal strain for production of multiple recombinant polypeptides having biological activity. The present invention also relates to methods for producing multiple recombinant polypeptides having biological activity in a filamentous fungal strain.
Novozymes, Inc.

new patent

Polypeptides having alpha-glucuronidase activity and polynucleotides encoding same

The present invention relates to isolated polypeptides having alpha-glucuronidase activity, catalytic domains and polynucleotides encoding the polypeptides, catalytic domains. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides or catalytic domains..
Novoyzmes A/s

new patent

Arabinofuranosidases

The present invention relates to isolated polypeptides having alpha-l-arabinofuranosidase activity and isolated nucleic acid sequences encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the nucleic acid sequences as well as methods for producing and using the polypeptides..
Novozymes A/s

new patent

Polypeptides with lipase activity and polynucleotides encoding same

Provided are isolated polypeptides with lipase activity and polynucleotides encoding the polypeptides. Also provided are nucleic acid constructs, vectors, and host cells comprising the polynucleotides, and methods of using the polypeptides..
Novozymes A/s

new patent

Polypeptides having alpha amylase activity

The present invention relates to polypeptides having alpha-amylase activity and polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides..
Novozymes A/s

new patent

Protein-based adhesives

Protein-based adhesives. In one embodiment of the present disclosure, an elastin-like polypeptide has a sequence ldgtl-(pgx1gvpgkgvpgx2gvpgx1gvpgx3gvpgx2gv)n-pvadrgmrle, wherein each x1 is selected from the group consisting of tyrosine (y), dihydroxyphenylalanine (dopa), and 3,4,5-trihydroxyphenylalanine (topa), wherein each x2 is selected from the group consisting of valine (v), y, dopa, and topa, wherein each x3 is selected from the group consisting of glutamic acid (e) and lysine (k), and wherein n is at or between 6 and 10 or higher or lower..

new patent

Protein-based adhesives

Protein-based adhesives. In one embodiment of the present disclosure, an elastin-like polypeptide has a sequence ldgtl-(pgx1gvpgkgvpgx2gvpgx1gvpgx3gvpgx2gv)n-pvadrgmrle, wherein each x1 is selected from the group consisting of tyrosine (y), dihydroxyphenylalanine (dopa), and 3,4,5-trihydroxyphenylalanine (topa), wherein each x2 is selected from the group consisting of valine (v), y, dopa, and topa, wherein each x3 is selected from the group consisting of glutamic acid (e) and lysine (k), and wherein n is at or between 6 and 10 or higher or lower..

new patent

Antibody polypeptides that antagonize cd40

Antibody polypeptides that specifically bind a novel epitope of human cd40 are provided. The antibody polypeptides do not exhibit cd40 agonist activity.
Domantis Limited

new patent

Human antigen binding proteins that bind betta-klotho, fgf receptors and complexes thereof

The present invention provides compositions and methods relating to or derived from antigen binding proteins activate fgf21-mediated signaling. In embodiments, the antigen binding proteins specifically bind to (i) β-klotho; (ii) fgfr1c, fgfr2c, fgfr3c or fgfr4; or (iii) a complex comprising β-klotho and one of fgfr1c, fgfr2c, fgfr3c, and fgfr4.
Amgen Inc.

new patent

Insulin-like growth factor 1 receptor -specific antibodies and uses thereof

The blood-brain barrier (bbb) prevents transport of molecules larger than 500 daltons from blood to brain. Receptor-mediated transcytosis (rmt) facilitates transport across the bbb of specific molecules that bind receptors on brain endothelial cells that form the bbb.
National Research Council Of Canada

new patent

Insulin-like growth factor 1 receptor -specific antibodies and uses thereof

The blood-brain barrier (bbb) prevents transport of molecules larger than 500 dal tons from blood to brain. Receptor-mediated transcytosis (rmt) facilitates transport across the bbb of specific molecules that bind receptors on brain endothelial cells that form the bbb.
National Research Council Of Canada

new patent

Antibodies to sericin and methods and kits using same

The present invention relates to antibodies that bind to a polypeptide at an epitope in the amino acid sequence of seq id no: 1 (e.g., a sericin polypeptide). The invention also provides methods and kits using the antibodies of the invention.
Cerapedics, Inc.

new patent

Polypeptide compositions with type vii collagen fibronectin type iii-like repeats and treatment methods for wound closure and healing

Disclosed are compositions and methods for accelerating wound closure and preventing inhibiting or reducing scarring or fibrosis. The methods of the present invention include administering to a person in need thereof an effective amount of a pharmaceutical composition comprising collagen 7 and/or one or more functional fragments or variants thereof.
University Of Southern California

new patent

Factor viii fusion protein

The present invention relates to modified coagulation factors. In particular, the present invention relates to conjugated factor viii molecules fused to a polypeptide such as e.g.
Novo Nordisk A/s

new patent

Methods for engineering t-cell receptors

The present invention provides a method for engineering a t-cell receptor domain polypeptide comprising at least one modification in a structural loop region of the t-cell receptor domain polypeptide and determining the binding of the t-cell receptor domain polypeptide to an epitope of an antigen, wherein the unmodified t-cell receptor domain polypeptide does not significantly bind to the epitope. The present invention also covers modified t cell receptor domain polypeptides, their use and libraries containing the modified t cell receptor domain polypeptides..
F-star Biotechnologische Forschungs- Und Entwicklungsges.m.b.h

new patent

Chemokine-immunoglobulin fusion polypeptides, compositions, making and use thereof

This application is directed to chemokine-immunoglobulin fusion polypeptides and chemokine-polymer conjugates. The fusion polypeptides and conjugates can be used for treating chemokine receptor-mediated disorders and modulating inflammation, inflammatory cell motility, cancer cell motility, or cancer cell survival..
Jyant Technologies, Inc.

new patent

Chimeric polypeptide comprising the fragment b of shiga toxin and peptides of therapeutic interest

Wherein b represents the b fragment of shiga toxin or a functional equivalent thereof, and x represents one or more polypeptides of therapeutic significance. Compositions for therapeutic use comprising the polypeptide b-x are also included..

new patent

Pro-apoptotic ras and raf peptides

The invention relates to pro-apoptotic peptides, useful in cancer treatment, and to chimeric peptides comprising a cell penetrating peptide linked to a pro-apoptotic peptide, wherein the pro-apoptotic peptide binds ras or raf proteins.. .
Institut Curie

new patent

Stabilized anti-microbial peptides

The present invention provides methods of designing and making structurally stabilized anti-microbial peptides for the prophylaxis and treatment of infection. Methods are also disclosed for designing stabilized anti-microbial peptides that are selectively lytic/cytotoxic to bacteria, allowing for internal use of anti-microbial peptides without mammalian membrane disruption and cytotoxicity..
Dana-farber Cancer Institute, Inc.

new patent

Synthetic polypeptide having a xylose import activity

This disclosure provides methods and compositions related to microbial gene expression. In one aspect, a synthetic polypeptide having a xylose import activity..
The Regents Of The University Of California

new patent

Compositions and methods for treating, including preventing, parvovirus infections and related diseases

Some embodiments of the invention include inventive polypeptides (e.g., mutant vp2 proteins) and virus-like particles made from the inventive polypeptides. Other embodiments of the invention include compositions for treating (e.g., preventing) parvovirus (e.g., erythrovirus or parvovirus b19) infection and other diseases.
University Of Louisville Research Foundation, Inc.

new patent

Cyclic peptide analogs and conjugates thereof

Provided are cyclic peptide analogs, conjugates comprising such compounds, and pharmaceutical compositions comprising such compounds and conjugates, and methods of treating cancer with such compounds and conjugates.. .
Sirenas Llc

new patent

Glycopeptide derivatives for the preservation and protection of biological materials and microorganisms

The present invention relates to a compound of the following formula (i): in which at least one and only one group chosen among r5, r6 and r7 is a group of the following formula: the present invention relates also to uses thereof for preservation and/or protection and/or regeneration of biological materials and or microorganisms and for cosmetic or dermato logical applications such as anti-aging, skin protection and skin regeneration; to culture, storage and/or preservation media comprising such a compound; to cosmetic or dermato logical compositions comprising such a compound; to processes for preparing such a compound; and to synthesis intermediates.. .
Tfchem

new patent

Chemokine binding polypeptides for treating autoimmunity, and inflammation

Novel polypeptides comprising a chemokine-binding peptide and an fc fragment are disclosed. The polypeptides are capable of binding to certain chemokines so as to modulate their activity.
Biokine Therapeutics Ltd.

new patent

Long acting proteins and peptides and methods of making and using the same

Disclosed is a method for refolding a protein or peptide that does not contain essential disulfides and that contains at least one free cysteine residue. Also disclosed are polymer ifn-γ conjugates that have been created by the chemical coupling of polymers such as polyethylene glycol moieties to ifn-γ, particularly via a free cysteine in the protein.
Bolder Biotechnology, Inc.

new patent

Cyclopropene amino acids and methods

The invention relates to a polypeptide comprising an amino acid having a cyclopropene group wherein said cyclopropene group is joined to the amino acid via a carbamate group. Suitably the cyclopropene group is a 1,3-disubstituted cyclopropene such as a 1,3-dimethylcyclopropene.
Medical Research Council





Follow us on Twitter
twitter icon@FreshPatents

###

This listing is a sample listing of patent applications related to Peptide for is only meant as a recent sample of applications filed, not a comprehensive history. There may be associated servicemarks and trademarks related to these patents. Please check with patent attorney if you need further assistance or plan to use for business purposes. This patent data is also published to the public by the USPTO and available for free on their website. Note that there may be alternative spellings for Peptide with additional patents listed. Browse our RSS directory or Search for other possible listings.


1.2568

file did exist - 3502

1 - 1 - 78