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 Semiconductor device patent thumbnailnew patent Semiconductor device
According to the present invention, a grease layer having a grease as a constituent material is provided in a filling region lying between a heat dissipation surface that is a bottom surface of a heat dissipation material of a semiconductor module and a surface of a cooler. Further, a seal material is formed on the surface of the cooler and covers the entire side surface region of the grease layer without any gap.
Mitsubishi Electric Corporation


 Novel compounds as rearranged during transfection (ret) inhibitors patent thumbnailnew patent Novel compounds as rearranged during transfection (ret) inhibitors
This invention relates to novel compounds which are inhibitors of the rearranged during transfection (ret) kinase, to pharmaceutical compositions containing them, to processes for their preparation, and to their use in therapy, alone or in combination, for the normalization of gastrointestinal sensitivity, motility and/or secretion and/or abdominal disorders or diseases and/or treatment related to diseases related to ret dysfunction or where modulation of ret activity may have therapeutic benefit including but not limited to all classifications of irritable bowel syndrome (ibs) including diarrhea-predominant, constipation-predominant or alternating stool pattern, functional bloating, functional constipation, functional diarrhea, unspecified functional bowel disorder, functional abdominal pain syndrome, chronic idiopathic constipation, functional esophageal disorders, functional gastroduodenal disorders, functional anorectal pain, inflammatory bowel disease, proliferative diseases such as non-small cell lung cancer, hepatocellular carcinoma, colorectal cancer, medullary thyroid cancer, follicular thyroid cancer, anaplastic thyroid cancer, papillary thyroid cancer, brain tumors, peritoneal cavity cancer, solid tumors, other lung cancer, head and neck cancer, gliomas, neuroblastomas, von hippel-lindau syndrome and kidney tumors, breast cancer, fallopian tube cancer, ovarian cancer, transitional cell cancer, prostate cancer, cancer of the esophagus and gastroesophageal junction, biliary cancer, adenocarcinoma, and any malignancy with increased ret kinase activity.. .
Glaxosmithkline Intellectual Property Development Limited


 Method and  producing a model findings object patent thumbnailMethod and producing a model findings object
A possibility is to be created of achieving the diagnosis of objects which are difficult to access. To this end, an apparatus and a method are proposed for producing a model findings object, in which image data or images of an original findings object are provided.
Siemens Aktiengesellschaft


 Babies' magic tea patent thumbnailBabies' magic tea
A method of preparing tea comprising steps (a) selecting raw materials, wherein the raw materials include organic cumin seeds and organic funnel seeds; (b) washing the raw materials thoroughly; (c) sterilization of the raw materials via air-drying; (d) mixing a predetermined amount of organic funnel seeds and a predetermined amount of organic cumin seeds into a tea bags, wherein the tea bag is 1.5 g; (e) boiling 8 ounces of water, wherein the tea bag is added to the boiling water for 2 to 3 minutes; and (f) serving the tea to a baby at room temperature wherein the tea is intended for babies to reduce colic, gas, constipation, and acid reflux.. .

 Storage controller, method, and storage system patent thumbnailStorage controller, method, and storage system
A storage controller is coupled to a plurality of storage devices, the storage controller is configured to receive a first write request of data, determine a first time when the first write request is received, specify, based on the first time, a first storage device included in the plurality of storage devices, write the data into the first storage device, receive a read request for the data, determine a second time when the read request is received, specify a second storage device included in the plurality of storage devices, wherein, in anticipation of a second write request received at the second time, the processor specifies the second storage device based on the second time, determine whether the first storage device is identical to the second storage device, and not read the data from the first storage device when the first storage device is identical to the second storage device.. .
Fujitsu Limited


 Opioid receptor antagonist for use in treating patients with severe constipation induced by high opiate dosage regimen patent thumbnailOpioid receptor antagonist for use in treating patients with severe constipation induced by high opiate dosage regimen
The present invention relates to a pharmaceutical composition comprising an opioid receptor antagonist, or a derivative or a pharmaceutically acceptable salt thereof, as an active substance, wherein the composition releases the active substance in a prolonged manner. The composition that is suitable for an administration period of at least twelve-hours for the treatment of severe opioid-induced constipation in patients receiving a daily dosage of opioid equivalent to at least 80 mg of morphine..
Develco Pharma Schweiz Ag


 Composition of opioid receptor antagonists for use in treatment of constipation with highly increased whole gut transit time patent thumbnailComposition of opioid receptor antagonists for use in treatment of constipation with highly increased whole gut transit time
The present invention relates to a composition comprising an opioid receptor antagonist in an extended release formulation for use in treating a patient with severe constipation characterised by a defined whole gut transit time.. .
Develco Pharma Schweiz Ag


 Dosage of naloxone patent thumbnailDosage of naloxone
The present invention relates to a pharmaceutical composition comprising a μ-receptor antagonist as an active substance, wherein the antagonist is prepared in an extended release formulation. The composition is intended for the treatment of patients with opioid-induced constipation, wherein the dosage of the μ-receptor agonist is independent of the opioid dosage.
Develco Pharma Schweiz Ag


 Combined bingo and keno lottery game patent thumbnailCombined bingo and keno lottery game
The object of a combined bingo and keno game is to fill in a prearranged pattern of numbers as in a bingo game and the selection of lucky numbers as in a keno game. As these numbers are called at random, a secondary game can be played simultaneously.
Intralot, Inc.


 Systems and methods of using an artificially intelligent database management system and interfaces for mobile, embedded, and other computing devices patent thumbnailSystems and methods of using an artificially intelligent database management system and interfaces for mobile, embedded, and other computing devices
The current disclosure generally relates to database management systems (dbmss) and may be generally directed to methods and systems of using artificial intelligence (i.e. Machine learning and/or anticipation functionalities, etc.) to learn a user's use of a dbms, store this “knowledge” in a knowledgebase, and anticipate the user's future operating intentions.

Systems and methods of using an artificially intelligent database management system and interfaces for mobile, embedded, and other computing devices


The current disclosure generally relates to database management systems (dbmss) and may be generally directed to methods and systems of using artificial intelligence (i.e. Machine learning and/or anticipation functionalities, etc.) to learn a user's use of a dbms, store this “knowledge” in a knowledgebase, and anticipate the user's future operating intentions.

Systems and methods of using an artificially intelligent database management system and interfaces for mobile, embedded, and other computing devices


The current disclosure generally relates to database management systems (dbmss) and may be generally directed to methods and systems of using artificial intelligence (i.e. Machine learning and/or anticipation functionalities, etc.) to learn a user's use of a dbms, store this “knowledge” in a knowledgebase, and anticipate the user's future operating intentions.

Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders


The invention provides novel guanylate cyclase-c agonist peptides and their use in the treatment of human diseases including gastrointestinal disorders, inflammation or cancer (e.g., a gastrointestinal cancer). The peptides can be administered either alone or in combination with an inhibitor of cgmp-dependent phosphodiesterase.
Synergy Pharmaceuticals, Inc.


Anthraquinone compounds and their uses


The present invention relates to a compound comprising a substituted or unsubstituted anthraquinone, or a salt or isomer thereof, for use in treating a disorder caused by or associated with dysfunctional ion channel activity. The invention finds utility in the treatment of disorders associated with smooth muscle tone and contraction, such as but not limited to partial hypertension; myocardial infarction; faecal incontinence; constipation; gastro oesophageal reflux; impaired gastrointestinal passage; urinary incontinence; erectile dysfunction; and asthma..
Dundalk Institute Of Technology


Social-driven precaching of accessible objects


A precaching system identifies an object, such as a media file, that a user accesses and then analyzes a social graph of the user to identify social graph contacts that may be interested in the object. Based on the content of the object—and the interests and connections of contacts in the social graph—the precaching system determines whether a particular contact in the user's social graph is likely also to access the object.
Cisco Technology, Inc.


Method of processing input/output in storage device and storage device and non-volatile memory device using the method


A method of processing input/output (i/o) in a storage device includes adjusting a read anticipation time based on a change of a resource management status related to operations of the storage device and performing an i/o processing operation at the storage device based on the adjusted read anticipation time. The i/o processing operation is performed to postpone an operation regarding a program command and perform a read command at higher priority than a write command at the storage device in a period from completion of a read operation at the storage device until the read anticipation time has elapsed..

System and multiple adjusting symbol changes during a wagering game


A gaming system performs a wagering game by determining an outcome, based at least in part, on one or more random elements. The wagering game uses a plurality of symbol bearing reels that includes at least one adjustable reel having an adjustable reel strip with one or more adjusting symbol positions thereon.
Wms Gaming Inc.


Method and system for anticipatory deployment of autonomously controlled vehicles


A method and system for management and anticipatory deployment of autonomously controlled vehicles are disclosed. According to one embodiment, a method may include calculating the geographic locations and periods of time where self-driving vehicles might experience the greatest probability of being requested to provide transportation services to passengers or cargo, and then communicating the resulting locations and times to self-driving vehicles, causing the vehicles to deploy themselves to those certain locations at those certain times, all prior to and in anticipation of specific requests being initiated by users or entities for such transport..
Tribal Rides, Inc.


Treatment of constipation-predominant irritable bowel syndrome


The invention provides methods for treating a patient with constipation-predominant irritable bowel syndrome by administering a therapeutically effective dose of linaclotide.. .
Forest Laboratories Holdings Limited


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Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders


The invention provides novel guanylate cyclase-c agonist peptides and their use in the treatment of human diseases including gastrointestinal disorder, inflammation or cancer (e.g., a gastrointestinal cancer). The peptides can be administered either alone or in combination with an inhibitor of cgmp-dependent phosphodiesterase.
Synergy Pharmaceuticals, Inc.


I/o bandwidth reduction using storage-level common page information


I/o bandwidth reduction using storage-level common page information is implemented by a storage server, in response to receiving a request from a client for a page stored at a first virtual address, determining that the first virtual address maps to a page that is a duplicate of a page stored at a second virtual address or that the first and second virtual addresses map to a deduplicated page within a storage system, and transmitting metadata to the client mapping the first virtual address to a second virtual address that also maps to the deduplicated page. For one embodiment, the metadata is transmitted in anticipation of a request for the redundant/deduplicated page via the second virtual address.
Netapp, Inc.


Adaptive data streaming method with push messages control


There is provided methods for managing streaming over communication networks. Server and client devices share a push policy so that the client device may anticipate data pushes by the server.
Canon Kabushiki Kaisha


Use activated emergency alert for a medical device


An epinephrine auto-injector use activated device detects and responds to usage of the auto-injector. The resulting use activated device includes an actuator for manual generation of an injection force, as by a patient's hand, and a medicinal reservoir or vial for storing a quantity of medication for injection.

Formulations comprising polyethylene glycol


The present invention concerns a solid formulation for oral administration as a solid comprising polyethylene glycol and a further solid such as mannitol. The formulation may be used to prevent gastrointestinal disorders such as constipation in healthy subjects.
Norgine Bv


Vehicle speed control system and method


Embodiments of the present invention provide a vehicle speed control system operable to cause a vehicle to operate in accordance with a target speed value by controlling an amount of brake torque applied by a braking system and an amount of drive torque applied by a powertrain to one or more wheels of the vehicle, the system being operable to detect a leading wheel step event in which a leading wheel encounters an abrupt increase in surface gradient, the system being operable in dependence on the detection of a leading wheel step event to cause brake torque to be applied against drive torque in anticipation of a trailing wheel step event corresponding to the leading wheel step event, the system being operable to cause the application of brake torque at least until a trailing wheel has travelled a sufficient distance to reach the location at which a leading wheel experienced the leading wheel step event.. .

Method and system for queue length analysis


A system and method for analysing queues in frames of video enables operators to preferably draw three regions of interest overlaid upon the video as short, medium, and long queue regions that form a notional queue area within the video. The regions are drawn with knowledge of, or in anticipation of, foreground objects such as individuals and vehicles waiting for service in a queue.

Method and a system for determining an angular velocity in turning for a rotary wing aircraft


A method and a system for determining an angular velocity in turning for a rotary wing aircraft in order to make turns that are coordinated relative to the ground or else relative to the air and in order to manage the transition between ground coordination and air coordination while taking account of the wind to which said aircraft is subjected. Said method serving to determine an angular velocity in yaw by means of an anticipation value a and a correction value b on the basis in particular of speeds of advance of the aircraft relative to the ground vasol and relative to the air vaair, of its lateral acceleration gy and of its lateral load factor ny..

Natural herbal compositions for rapid removal of metabolic toxins in the body


The present invention provides a natural herbal composition for rapid removal of metabolic toxins in the body, to solve the problems of existing herbal compositions such as slow efficacy for such symptoms as constipation, bad breath, acnes caused by accumulated toxins in the body, side and toxic effects, etc. The natural herbal composition comprises the following ingredients (by mass): mangosteen extract, aloe extract, hot water extract of mixture of dandelion 1-30, angelica sinensis 1-20, polygonum multiflorum 1-30, cinnamomum cassia 3-16, rheum officinale 4-20, glycyrrhiza uralensis 3-10, panax notoginseng 3-10, atractylodes macrocephala 5-15, wherein the mass ratio of mangosteen fruit extract to aloe extract is 3:1-5, and the mass ratio of mangosteen and aloe extracts to the hot water extract is 2:1-5..

Legume/grain based food product with prebiotic/probiotic source


A minimally processed ready-to-eat legume/grain product is provided containing a significant amount of probiotic fiber and a probiotic source or is consumed with a probiotic source for the prevention and/or treatment of inflammatory chronic conditions such as inflammatory, autoimmune chronic conditions such as irritable bowel syndrome (ibs), digestive disorders such chronic constipation, gastric acid reflux, diabetes, heart disease, obesity, some type of cancer, malabsorptive disorders, eczema as well mental health disorders such as anxiety disorder. The present invention is suitable for men and woman of all ages..

Methods and compositions for the treatment of gastrointestinal disorders


Compositions and related methods for treating ibs and other gastrointestinal disorders and conditions (e.g., gastrointestinal motility disorders, functional gastrointestinal disorders, gastroesophageal reflux disease (gerd), duodenogastric reflux, crohn's disease, ulcerative colitis, inflammatory bowel disease, functional heartburn, dyspepsia (including functional dyspepsia or nonulcer dyspepsia), gastroparesis, chronic intestinal pseudo-obstruction (or colonic pseudoobstruction), and disorders and conditions associated with constipation, e.g., constipation associated with use of opiate pain killers, post-surgical constipation, and constipation associated with neuropathic disorders as well as other conditions and disorders are described. The compositions feature peptides that activate the guanylate cyclase c (gc-c) receptor..
Ironwood Pharmaceuticals, Inc.


Block-level predictive data migration


An apparatus for migrating data in a tiered storage architecture includes one or more processors and one or more memory devices coupled to the processors and storing instructions for execution by the processors. The instructions cause the one or more processors to: track temperature (i.e., frequency of access) of data blocks in a tiered storage architecture; generate heat maps indicating the temperature of the data blocks across different time intervals; process the heat maps using an image processing algorithm; compress the heat maps to reduce the size of the heat maps; compare the heat maps from the time intervals to identify temperature patterns occurring over time; predict, from the temperature patterns, when selected data blocks will change in temperature; and migrate the selected data blocks between tiers of the tiered storage architecture in anticipation of their changes in temperature..
International Business Machines Corporation


Methods of treating irritable bowel syndrome


The present invention provides a method for treating irritable bowel syndrome (ibs) in a subject in need thereof. The treatment can include administering about 550 mg of rifaximin three times per day and about 500 mg of neomycin two times per day for 14 days to the subject to treat the ibs.
Cedars-sinai Medical Center


System and controlling the power mode of operation of a memory device


A system and method are provided for controlling the power mode of operation of a memory device. The system includes a processing device for performing processing operations on data, and a memory controller associated with the memory device, the memory device being used to store data for access by the processing device.
Arm Limited


Content preview generation using social network analysis


Disclosed is a system and method for generating a preview of a digital content item using social network analysis. Members of a social network who acquire the digital content item may identify interesting portions of the digital content.
International Business Machines Corporation


Method and system for pre-cooling traction battery in anticipation of recharging at charging station


Methods and systems for electric vehicles, such as a battery electric vehicle (bev) and a plug-in hybrid electric vehicle (phev), include pre-cooling a traction battery of the vehicle upon an indication that the vehicle is being driven to a charging station. The pre-cooling is done by an on-board battery cooling system.
Ford Global Technologies, Llc


Methods of isolating microorganisms and uses thereof


Provided herein are methods for preparing a microbiome sample for transplantation into a subject in need thereof. In particular, the methods and compositions relate to methods of repopulating the the microbiome of a subject in the treatment of gastrointestinal maladies e.g., diarrhea and/or constipation..
President And Fellows Of Harvard College


Adenosine analogs and their use


The invention provides adenosine analog compounds that act at p2y receptors, e.g., the p2y2 receptor, including pharmaceutical compositions; and uses thereof to treat or prevent diseases associated with that receptor, e.g., disorders relating to mucus secretion, such as cystic fibrosis, chronic obstructive pulmonary disorder (copd), asthma, constipation, chronic idiopathic constipation, dry mouth (xerostomia), gum disease, and gastrointestinal problems caused by radiation and chemotherapy for cancer.. .
Microdose Therapeutx, Inc.


Pyrazole derivative and use thereof for medical purposes


The present invention provides pyrazole derivatives, uses thereof for medical purposes and so on. More particularly, the present invention relates to pharmaceuticals useful for the prevention or treatment of constipation, which comprise as an active ingredient 3-(3-{4-[3-(β-d-glucopyranosyloxy)-5-isopropyl-1h-pyrazol-4-ylmethyl]-3-methylphenoxy}propylamino)-2,2-dimethylpropionamide, or a pharmaceutically acceptable salt thereof.
Kissei Pharmaceutical Co., Ltd.


Epoxy resin composition, cured product, heat radiating material, and electronic member


The present invention provides an epoxy resin composition including 2,2′,7,7′-tetraglycidyloxy-1,1′-binaphthalene as an epoxy resin (a), and a filler (b). Further, the present invention provides an epoxy resin composition in which the filler (b) in the epoxy resin composition is a thermally conductive filler and an epoxy resin composition in which the filler (b) is silica.
Dic Corporation


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Copper heat dissipation material, carrier-attached copper foil, connector, terminal, laminate, shield material, printed-wiring board, metal processed member, electronic device and manufacturing the printed wiring board


A copper heat dissipation material having a satisfactory heat dissipation performance is provided. The copper heat dissipation material has an alloy layer containing at least one metal selected from cu, co, ni, w, p, zn, cr, fe, sn and mo on one or both surfaces, in which surface roughness sz of the one or both surfaces, measured by a laser microscope using laser light of 405 nm in wavelength, is 5 μm or more..
Jx Nippon Mining & Metals Corporation


Wireless beacon devices providing crosswalk management through communication device connections


There are provided systems and methods for wireless beacon devices providing crosswalk management through communication device connections. A user may travel with a device, such as a communication device, that includes a communication module that may utilize specialized hardware features to establish short range wireless communications with nearby wireless beacons.

Herbal supplements and methods of use thereof


In one embodiment, the present application provides an herbal supplement and method for treating bloating, constipation and/or weight gain in a human subject comprising orally administering to a subject in need thereof an effective amount of the herbal supplement comprising a red quebracho extract. In other embodiments, the supplement may additionally include a triterpenoid saponin, an anti-spasmodic agent, or both..

System and automated alerts in anticipation of inappropriate communication


A method for providing a sensitive text alert includes monitoring a key selected on a keyboard of a computer system. The key selected is reported to a key-logger application executing on the computer system.
Conversational Logic Ltd.


Hierarchical allocation for file system storage device


Aspects of the subject matter described herein relate to storage allocation. In aspects, a hierarchical data structure is used to track allocation data for storage managed by a file system.
Microsoft Technology Licensing, Llc


Connection point for metal structure


A connecting node for metallic structures, specifically for structures based on props or pillars (1) wherewith cross beams (2) are associated, wherein said pillars (1) incorporate rosettes (3) separated by a predetermined distance, each of which having a polygonal window (31) and at least one circular hole (32); while the beams (2) include on their edges a fork (4) having a stub (41) with a polygonal configuration that projects from the lower side and has a configuration equivalent to the window (31) and at least one hole (42) in correspondence with the hole (32) of the rosettes (3); the foregoing in anticipation that a fork (4) will be fitted into a pair of rosettes (3) without possibility of sideways movement of the beam (2) and, once the structure is assembled, that it will be immobilised by means of at least one screw (6) which, passing through holes (32) and (42), establishes the definitive connection.. .
Industria Metálicas Anro, S.l.


Universal system for measurement instruments for industrial hygiene and environment


Universal system for measurement instruments for industrial hygiene and environment, consisting of a data collector (1), this equipment will be a portable device or computer equipped with microsoft windows or android operating system, used to communicate with following instruments: wet bulb globe temperature thermometer index (wbgt) (2), sound level meter (3), noisedosimeter (4), vibration meter for hand, arm and whole body (5), fixed type portable gas detectors (6), alpha, beta, gamma and/or neutrons ionizing radiation detector (7), non-ionizing radiation detector(8), lux meters (9), iaq systems—internal air quality (10) and iaq systems—internal water quality (11). Its application field belongs to the area of occupational hygiene applicable to industries or businesses in general in which workers are exposed to physical, chemical and biological agents causing occupational diseases..

Bicyclic derivative containing pyrimidine ring, and preparation method therefor


The present invention provides: a bicyclic derivative comprising a pyrimidine ring, or a pharmaceutically acceptable salt thereof; a preparation method therefor, a pharmaceutical composition comprising the same; and a use therefor. According to the present invention, the bicyclic compound derivative comprising a pyrimidine ring, or a pharmaceutically acceptable salt thereof acts as a 5-ht4 receptor agonist, and thus can be usefully applied to the prevention or treatment of dysfunction in gastrointestinal motility, for example, gastrointestinal diseases such as gastroesophageal reflux disease (gerd), constipation, irritable bowel syndrome (ibs), dyspepsia, post-operative ileus, delayed gastric emptying, gastroparesis, intestinal pseudo-obstruction, drug-induced delayed transit, diabetic gastric atony and the like..
Yuhan Corporation


Near infrared oxygen concentration sensor for palpation


A near-infrared oxygen concentration sensor for palpation 1 to be attached to a finger pad on a leading end side from a distal interphalangeal joint of a use's finger includes: a base material 2 to be attached to a finger pad; a light emitting unit 4 that is disposed on the base material and that emits light having at least two wavelengths, including near-infrared light, to a test subject; light receiving units 5a and 5b that are disposed on the base material and that receives a measurement light from the light emitting element through the test subject; and a light receiving unit 3 that is disposed at least between the light emitting unit or the light receiving unit and the finger pad and that prevents the measurement light having passed through the user's finger from being led to the light receiving unit.. .
National University Corporation Hamamatsu University School Of Medicine


Output processing system, output processing device, and non-transitory computer-readable recording medium


An output processing system includes a source device and a destination device. The source device transfers output information created in anticipation of a target output device in an output color space whose components are colors of color material, together with target device property information indicating characteristics of the target output device.
Fuji Xerox Co., Ltd.


Facilitating intelligent gathering of data and dynamic setting of event expectations for event invitees on computing devices


A mechanism is described for facilitating data gathering and expectations setting according to one embodiment. A method of embodiments, as described herein, includes detecting an invitation relating to an event, where the invitation may include an invitation to an invitee to attend the event.

Optimization of a multi-view display


Described herein is a multi-view display (based on spatial and/or temporal multiplexing) having an optimization mechanism that dynamically adjust views based upon detected state changes with respect to one or more views. The optimization mechanism determines viewing parameters (e.g., brightness and/or colors) for a view based upon a current position of the view, and/or on the multi-view display's capabilities.
Microsoft Technology Licensing, Llc


Method of enhancing customer relationship management content and workflow


Forward-looking sales activities are poorly served by existing customer relationship managements systems, as the customer information those systems maintain by definition does not include the speculatively interested “leads” pursued in initial sales contacts. An enrichment database, asynchronously loaded with corporate and optionally individual contact information in anticipation of use, provides real-time access to information in support of such first customer contacts.
Hubstar, Inc.


Systems and methods for enabling local caching for remote storage devices over a network via nvme controller


A new approach is proposed that contemplates systems and methods to support mapping/importing remote storage devices as nvme namespace(s) via an nvme controller using a storage network protocol and utilizing one or more storage devices locally coupled to the nvme controller as caches for fast access to the mapped remote storage devices. The nvme controller exports and presents the nvme namespace(s) of the remote storage devices to one or more vms running on a host attached to the nvme controller.
Cavium, Inc.


Systems and methods for providing predictive vehicle dynamics


Systems and methods for providing predictive vehicle dynamics are described herein. Accordingly, embodiments of a method may include predicting a route of a vehicle, determining a route feature along the route, and determining a user-desired speed for traversing the route.
Toyota Motor Engineering & Manufacturing North America, Inc.


Probiotic strains for use in improving the enteric nervous system


The invention relates to the use of lactic acid bacteria, for use in modifying the enteric nervous system and more particularly in treating and/or preventing intestinal disorders such as constipation and/or irritable bowel disease.. .
Compagne Gervais Danone


Bonding, communication and control system for a shipping and/or storage unit


A bonding, communication and control system that, via multiple digital and analog inputs and outputs provided by an on-the-go ready microcontroller, is capable of integrating the function of components required for a device to perform its tasks. Each invention unit has the minimum amount of built in hardware to support its features.

System and uplink timing synchronization in conjunction with discontinuous reception


Systems and methods for controlling sounding reference signal transmission are provided; a user equipment starts transmitting the sounding reference signal in anticipation of uplink data transmission, and then discontinues transmitting the sounding reference signal after completion of uplink data transmission.. .
Blackberry Limited


Technique for synchronizing iommu memory de-registration and incoming i/o data


A technique synchronizes de-registration of registered memory and incoming input/output (i/o) data received from an i/0 device for storage in a memory of a computer system. Registration and de-registration of the memory with an i/o memory management unit (iommu) are illustratively performed by an i/o device driver of the computer system in anticipation of (or in response to) an i/o request to store the incoming i/o data in buffers of the memory.
Netapp, Inc.


Dual use oral pharmaceutical composition tablets of sulfate salts and methods of use thereof


The present invention is generally directed to an oral pharmaceutical tablet composition comprising a sulfate salt, for example, sodium sulfate, wherein the composition is capable of administration by direct oral ingestion and by disintegration in water prior to oral ingestion. The present invention is further directed to use of such oral pharmaceutical tablet formulations to induce laxation or to treat or prevent constipation..
Braintree Laboratories, Inc.


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System and a load anticipation feature and its tuning a generating set


A method, system and computer software for providing a load anticipation feature for a diesel generating set including a diesel engine, a generator, a speed governor, and an automatic voltage regulator generator in a power system and computer data processor apparatus and computer executable instructions for ascertaining an equivalent linear speed control system whose response approximately matches the non-linear speed response of the diesel generating set; ascertaining at least one programmable parameter of the load anticipation feature based on a real power load applied to the diesel generating set and a desired speed response of the linear speed control system; generating a control output based on a measured real power load and at least one programmable parameter of the load anticipation feature; the speed governor receiving the control output and adjusting the speed of the diesel engine based on the control output.. .
Basler Electric Company


System and automation of rotorcraft entry into autorotation and maintenance of stabilized autorotation


The system is configured for automation of rotorcraft entry into autorotation. The system can provide a means to assist the flight crew of a rotorcraft in maintaining rotor speed following loss of engine power.
Bell Helicopter Textron Inc.


Adaptive resource management of a cluster of host computers using predicted data


A resource management system and method for performing resource management operations in a distributed computer system uses predicted resource demands for a specified time in the future to change a resource management option of a resource management analysis algorithm prior to the specified time so that the resource management analysis algorithm can be executed in anticipation of the predicted resource demands at the specified time.. .
Vmware, Inc.


Palpation evaluation or diagnosis device, system and method


A physical therapy or palpation evaluation or diagnosis device, system, and method for evaluating the condition of a patient's body, for example, the spine and/or soft tissue. The physical therapist currently uses palpation to subjectively evaluate the condition of the spine, soft tissue and/or muscle of the patient.

Palpation diagnostic device


The present invention relates to a palpation diagnostic device, which comprises an optical pressure sensor embedded in a holder; wherein the optical pressure sensor is an optical fiber sensor, or a micro-fabricated waveguide sensor to be disposed on a finger or a palm; and the optical pressure sensor is configured to receive an optical signal whose intensity is attenuated when a force is applied on the optical pressure sensors. Therefore, the palpation diagnostic device of the present invention can provide high sensing sensitivity by attenuating the intensity of the optical signal in the optical pressure sensors which a force is applied on, so it can provide precise and immediate information based on quantitative feedback for the users..
National Cheng Kung University


Anticipatory hand-off setup between networks


A system and method for performing anticipatory hand-off setup between communication networks. Various aspects of the present invention may, for example and without limitation, provide a system and method for performing anticipatory hand-off setup between communication networks.
Broadcom Corporation


Pyridine derivatives as rearranged during transfection (ret) kinase inhibitors


This invention relates to novel compounds which are inhibitors of the rearranged during transfection (ret) kinase, to pharmaceutical compositions containing them, to processes for their preparation, and to their use in therapy, alone or in combination, for the normalization of gastrointestinal sensitivity, motility and/or secretion and/or abdominal disorders or diseases and/or treatment related to diseases related to ret dysfunction or where modulation of ret activity may have therapeutic benefit including but not limited to all classifications of irritable bowel syndrome (ibs) including diarrhea-predominant, constipation-predominant or alternating stool pattern, functional bloating, functional constipation, functional diarrhea, unspecified functional bowel disorder, functional abdominal pain syndrome, chronic idiopathic constipation, functional esophageal disorders, functional gastroduodenal disorders, functional anorectal pain, inflammatory bowel disease, proliferative diseases such as non-small cell lung cancer, hepatocellular carcinoma, colorectal cancer, medullary thyroid cancer, follicular thyroid cancer, anaplastic thyroid cancer, papillary thyroid cancer, brain tumors, peritoneal cavity cancer, solid tumors, other lung cancer, head and neck cancer, gliomas, neuroblastomas, von hippel-lindau syndrome and kidney tumors, breast cancer, fallopian tube cancer, ovarian cancer, transitional cell cancer, prostate cancer, cancer of the esophagus and gastroesophageal junction, biliary cancer, adenocarcinoma, and any malignancy with increased ret kinase activity.. .
Glaxosmithkline Intellectual Property Development Limited


Prefetching of discontiguous storage locations in anticipation of transactional execution


Discontiguous storage locations are prefetched by a prefetch instruction. Addresses of the discontiguous storage locations are provided by a list directly or indirectly specified by a parameter of the prefetch instruction, along with metadata and information about the list entries.
International Business Machines Corporation


Prefetching of discontiguous storage locations in anticipation of transactional execution


Discontiguous storage locations are prefetched by a prefetch instruction. Addresses of the discontiguous storage locations are provided by a list directly or indirectly specified by a parameter of the prefetch instruction, along with metadata and information about the list entries.
International Business Machines Corporation


Hydroxyindalpine derivatives and their medical use


The present invention relates to hydroxyindalpine derivatives of formula (i) as defined herein and pharmaceutical compositions comprising these compounds, as well as their medical use, particularly in the treatment or prevention of gastrointestinal diseases/disorders, such as constipation and functional dyspepsia.. .
Technische UniversitÄt MÜnchen


Prophylactic or therapeutic drug for constipation


New drugs useful in the prevention or treatment of constipation are provided, in which sglt1 inhibiting compounds, in particular, a 4-isopropylphenyl glucitol compound represented by the following formula (i), or pharmaceutically acceptable salts thereof are contained as an active ingredient:. .
Taisho Pharmaceutical Co., Ltd.


Crystalline form of linaclotide


Linaclotide is a guanylate cyclase type c receptor (gcc) agonist used in the treatment of gastrointestinal disorders and conditions, including irritable bowel syndrome and chronic constipation. Crystalline form ii of linaclotide is prepared in high purity and yields and shows superior chemical stability in comparison to known crystal or amorphous forms of linaclotide.
Sandoz Ag


Block-level predictive data migration


A method for migrating data in a tiered storage architecture is disclosed. In one embodiment, such a method includes tracking the temperature of data blocks in a tiered storage architecture, where the temperature indicates the frequency the data blocks are accessed.
International Business Machines Corporation


Systems and methods for egr control


Methods and systems are provided for reducing torque transients experienced when a dedicated egr cylinder is deactivated to reduce egr. Before deactivating the dedicated cylinder, an intake throttle position and spark timing of remaining engine cylinders is adjusted to build-up torque reserve in anticipation of a negative torque transient at deactivation.
Ford Global Technologies, Llc


Decompression instruments and related methods


A decompression instrument is disclosed for removing impacted stool from a patient with long standing chronic constipation. The instrument is configured to enter the gastrointestinal tract through the anus to remove the impacted stool.

High speed elastrographic property mapping of lumens utilizing micropalpation delivered from an oct-equipped catheter tip


A method for performing elastographic deformation mapping of tissues and plaques comprises: introducing a distal portion of a catheter to an interior of an interior body of a patient; applying, from a palpator in the distal portion, one of a directed fluid or a mechanical indenter to produce a surface-applied palpation force to a target area of the interior body to mechanically displace the interior body and cause elastographic deformation of the target area of one or more surface and subsurface tissues and plaques; and directing and delivering an oct (optical coherence tomography) beam, from an oct imaging sensor in the distal portion, for oct deformation detection including elastographic deformation measurement to provide elastographic mapping of the target area.. .
St. Jude Medical, Inc.


Enhancing jitter buffer performance through radio level feedback


A jitter buffer in a voice over lte receiver may be influenced by radio level feedback (rlf) from both local and remote endpoints to preemptively adjust the jitter buffer delay in anticipation of predicted future losses that have a high probability of occurring. The radio events of the rlf and the scenarios that trigger the preemptive adjustments may be identified, and their use may be expressed in terms of mathematical formulas.
Apple Inc.


Federated cache network


A system and method, called federated cache network (fcn), places and optimizes content caches located in an access or backhaul network of a network service provider or multiple system operator. A fcn comprises a trunk cache and a plurality of branch caches and leaf caches.
Badu Networks Inc.


Electronic funds transaction system and method


An electronic funds transfer system comprising: at least one user account, each of which is associated with a user of the system; at least one partner organisation account, each of which is associated with a partner organisation of the system; a system administrator adapted to receive notification from said partner organisation of funds to be transferred to said user account; and a provider fund containing funds for financing transactions between said partner organisation and said user, wherein said system administrator, on receiving an electronic funds transfer notification from a partner organisation, is adapted to directly or indirectly facilitate transfer of an allocated fund notified by said partner organisation to an allocated user account in real time in anticipation of receipt of the allocated fund by said provider fund from a partner organisation funds manager after clearance of the allocated fund from said partner organisation funds manager.. .
Redmond Company Pty Ltd.


Bowel cleansing composition


The present invention relates to a bowel cleansing preparation comprising, as a first cleansing ingredient, a certain sugar alcohol such as xylitol and sorbitol; as a second cleansing ingredient, ascorbic acid or a mixture of ascorbic acid and a salt of ascorbic acid; and aqueous solvent, wherein the concentration of said first cleansing ingredient is 10 g/l to 500 g/l based on the total preparation, the concentration of said second cleansing ingredient is 15 g/l to 500 g/l based on the total preparation, and the volume of said aqueous solvent is 0.1 l to 1.0 l. The bowel cleansing preparation has excellent cleansing efficacy, improved ease of administration and safety and can thus be used for bowel preparation prior to colonoscopy, therapeutic endoscopy, abdominal surgery and anal surgery for hemorrhoid as well as for the treatment and alleviation of diseases such as chronic and acute constipation..

System, method, and computer program product for media publishing request processing


A system, method, and computer program product for publishing transcoded media content in response to publishing service requests from end users. A user request for media content, is processed intelligently, either by directing the processing of the request to one of a set of transcoding servers so as to effectively balance the load among the servers, or by directing the processing of the request to an appropriate alternative means for satisfying the request.
Sony Corporation


Traffic light anticipation


A vehicle includes at least one autonomous driving sensor configured to detect a traffic flow pattern relative to an intersection. An autonomous mode controller is configured to determine the state of the traffic control device.
Ford Global Technologies, Llc


Novel enteric combination therapy


There is disclosed herein a composition for treating gastrointestinal or neurological disorders, constipation, functional constipation, irritable bowel syndrome, diverticulitis, travelers diarrhoea, chronic idiopathic nausea, ibd-associated constipation and diarrhoea, pseudo-obstruction, diabetic gastroparesis, cyclic vomiting, reflux oesophagitis, autism enteropathy, flatulence, halitosis, chronic fatigue, bloating, proctalgia fugax, parkinsons disease, ms, alzheimers disease, motor neurone disease or autism, the composition comprising: (i) at least two anti-clostridial agents selected from the group consisting of: vancomycin, vancomycin derivatives, a multi-valent polymer of vancomycin, aminoglycosides, nitroimidazoles, ansamysins, nifuroxazide, colchicine, prucalopride, prokinetic agent and 5-aminosalicylic acid; or (ii) at least one anti-clostridial agent selected from the above combined with an opioid blocking agent. There is also disclosed herein a method of treating various gastrointestinal or neurological disorders, constipation, functional constipation, irritable bowel syndrome, diverticulitis, travelers diarrhoea, chronic idiopathic nausea, ibd-associated constipation and diarrhoea, pseudo-obstruction, diabetic gastroparesis, cyclic vomiting, reflux oesophagitis, autism enteropathy, flatulence, halitosis, chronic fatigue, bloating, proctalgia fugax, parkinsons disease, ms, alzheimers disease, motor neurone disease or autism, the method comprising administering orally, via enema or by suppository: (i) a composition of the invention; (ii) at least two anti-clostridial agents selected from the group consisting of: vancomycin, vancomycin derivatives, a multi-valent polymer of vancomycin, aminoglycosides, nitroimidazoles, ansamysins, nifuroxazide, colchicine, prucalopride, prokinetic agent and 5-aminosalicylic acid; or (iii) at least one anti-clostridial agent selected from the above and an opioid blocking agent to a patient in need of such treatment..

Method for wifi connectivity loss anticipation


A method for anticipating the loss of connectivity between a mobile device and a wireless short-range access point among a plurality of such wireless access points, this method comprising the following steps: —collecting a plurality of paths corresponding to the mobile device movements within the coverage areas of the access points to which the mobile device was successively associated without loss of connectivity, each path comprising a root access point at which a connectivity is originated and a dead-end access point at which the connectivity is lost; —detecting the current access point to which the mobile device is currently associated; identifying the paths comprising the current access point; —computing the risks of losing the connectivity when following each of the identified paths from the current access point to the root access point or to the dead-end access point of each of the identified paths.. .
Alcatel Lucent


Processing dns queries to identify pre-processing information


Systems and methods for processing a dns query to identify and implement pre-processing information by a dns server component in anticipation of a corresponding content request from a client computing device are provided. The pre-processing information can correspond to identification of content to be preloaded or other actions to be implemented by one or more computing devices in association with an anticipated client content request.
Amazon Technologies, Inc.


Systems and methods for enabling local caching for remote storage devices over a network via nvme controller


A new approach is proposed that contemplates systems and methods to support mapping/importing remote storage devices as nvme namespace(s) via an nvme controller using a storage network protocol and utilizing one or more storage devices locally coupled to the nvme controller as caches for fast access to the mapped remote storage devices. The nvme controller exports and presents the nvme namespace(s) of the remote storage devices to one or more vms running on a host attached to the nvme controller.
Cavium, Inc.


Pre-fetching grid blocks by user intent


Disclosed herein are systems, methods, and software to enhance user experiences with online services and hosted content. In at least one implementation, an initial user interaction with a user interface to a local model of content is detected.
Microsoft Corporation


Campus safety system


A personal protection device carried or worn by a user has a simple actuator button and transmitter operable within a mesh network covering a monitored environment such as a college campus or industrial park transmits an exigent assistance call to a first responder such as security or dps (department of public safety) personnel for urgent response. The system for deploying and monitoring the personal protection devices distributes or otherwise transfers possession of an actuator device to a user, such that the actuator device is adapted for wearing or disposing on the user in anticipation of a sudden exigent situation.
Worcester Polytechnic Institute


Sports training device


An athletic training device trains athletes to observe the collision between a ball and bat, club, racquet, or the like. The training device may provide a unique event, such as a flashing light, at the moment of the collision.

Method for freeing a vehicle by rocking


A method of rocking a vehicle free, the vehicle having a drive-train (1) with a torque adjusting element (3) which transmits drive torque to a vehicle wheel (5). The adjusting element (3) is controlled as a function of an accelerator pedal position.

Composition for preventing, alleviating or treating constipation, containing high hardness mineral water prepared from deep ocean water or desalinated groundwater


The present invention relates to a functional composition for preventing, alleviating or treating constipation, containing high hardness mineral water prepared from deep ocean water or desalinated groundwater, and a method therefor. The present invention contains high hardness mineral water prepared from deep ocean water or desalinated groundwater as an active ingredient so as to be safe to the human body, and thus can be useful for treating constipation of a cancer patient and constipation of a regular person..

Gaming device having conditional reel functionality


Embodiments of the present invention set forth systems, apparatuses and methods for providing conditional reel functionality in gaming devices. Accordingly, a gaming device can be configured to increase the variety of outcomes and sense of anticipation in a video slot game, by varying the composition of symbols on one or more reels based on outcomes of previously determined reels.

Method of monitoring unconventional hydrocarbon exploration and development sites


The present invention is a method of monitoring recovery site hydrocarbons (hc) using an unconventional method which permits quantifying the hc present in zones above the exploration and development zone. The method according to the invention is based on the adjustment of a model describing the gas concentration as a function of time, using in-situ geochemical analyses of rare gases and, when appropriate, of injected gas used for fracturing, contained in fluid phases of subsoil samples.

Sensor-activated rhythm analysis: a heuristic system for predicting arrhythmias by time-correlated electrocardiographic and non-electrocardiographic testing


A method and apparatus for monitoring biosignals (e.g. Bioelectrical signals) is disclosed.

Method and a system for a fast bus transfer in an electrical power system


A method for synchronizing and connecting a first sub power system with a second sub power system with an intelligent electronic device (ied) by use of at least one switching device between the first sub power system and the second sub power system in an electrical power system is provided. The ted monitors power supply parameters such as voltage magnitude, phase and other derived parameters such as voltage and phase differences in the first sub power system and the second sub power system to identify at least one instance for fast bus transfer where the two sub systems have acceptable differences in magnitude and phase.
Abb Technology Ltd






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