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new patent Pulse-palpating proximal and remote pulse palpation
A pulse-palpating apparatus, comprising: a pulse-palpating device, including a pulse-palpating-end communicating means and a pressure-exerting detecting means which exerts a force on pulse taking positions on a human body via the detecting member, which detects a pulse information on the pulse taking positions; and a network-connected controlling device, including a network-connected controlling means and a controlling-end communicating means, in which the network-connected controlling means is configured to generate force-intensity-controlling information, and the controlling-end communicating means transmits the force-intensity-controlling information to the pulse-palpating-end communicating means via network transmission, and receives the pulse information of the detecting member via network transmission. The pulse-palpating apparatus is provided for users to perform self-pulse diagnosis, and for medical practitioners to perform remote pulse palpation on a subject via network..

Palpation assisting apparatus, palpation assisting system, and palpation assisting method
A palpation assisting apparatus includes a synchronization controller configured to synchronize a timing of acquiring pressure data output from a pressure sensor attached to a position in contact with a lesion part with a timing of acquiring positional information of a marker attached to a position corresponding to the pressure sensor, and an entering part configured to store, in a storage part, the pressure data and the positional information of the marker that are acquired at the synchronized timing in association with time information indicating a time at which the pressure data and the positional information are acquired.. .
Fujitsu Limited


Application bundle preloading
Disclosed aspects include managing a set of application bundles for processing a stream of tuples. A set of application bundles which are installed on a second compute node is monitored by a first compute node.
International Business Machines Corporation


Application bundle preloading
Disclosed aspects include managing a set of application bundles for processing a stream of tuples. A set of application bundles which are installed on a second compute node is monitored by a first compute node.
International Business Machines Corporation


Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
The invention provides novel guanylate cyclase-c agonist peptides and their use in the treatment of human diseases including gastrointestinal disorders, inflammation or cancer (e.g., a gastrointestinal cancer). The peptides can be administered either alone or in combination with an inhibitor of cgmp-dependent phosphodiesterase.
Synergy Pharmaceuticals, Inc.


System for measuring plant attributes using a priori plant maps
A system for measuring plant attributes comprises a plant attribute sensor (103, 108, 110); a digital a priori plant location map (118); and an ecu (126) coupled to the plant attribute sensor (103, 108, 110) and configured to retrieve and use the a priori plant map and to anticipate a plant measurement based upon the a priori plant map and to use that anticipation to improve the accuracy of the plant measurement.. .
Deere & Company


Implementing integrated circuit designs using depopulation and repopulation operations
Circuit design computing equipment may perform depopulation operations, constraint generation, and repopulation operations in a circuit design in anticipation of register retiming operations. A depopulation operation before placement and/or before routing operations may prevent the respective placement and/or routing operations from placing and/or routing registers from the circuit design.
Altera Corporation


Systems, apparatuses, and methods for patient simulators
Provided herein are systems, methods, and apparatuses for simulating ailments that can be diagnosed by an abdominal palpation exam. Furthermore, provided herein are systems, methods, and apparatuses for analyzing an abdominal palpation exam.
Acdet Llc


Metal 3d printer
A metal 3-d printer includes a powder layer formation device having a blade for planarizing metal powder, a table driving device lowering a table by a predetermined lowering distance in anticipation of a formation of a powder layer, a laser irradiating device irradiating a laser beam at the powder layer to form a sintered layer having a predetermined upper surface region, a numerical control apparatus controlling the powder layer formation device, the table driving device, the laser irradiating device and a machining apparatus. When the blade collides with an obstacle formed on an upper most sintered layer, an end mill is lowered according to a predetermined lowering distance such that a lower end of the end mill is lower than an upper surface of the powder layer, and moves the end mill across a predetermined upper surface region of the uppermost sintered layer to remove the obstacle..
Sodick Co., Ltd.


Use of a sweet whey containing infant formula for promoting the postnatal neuronal development of the infant gastrointestinal tract, and the establishment of the intestinal functions that it controls
The present invention relates to administration of sweet whey protein (swp) for promoting the enteric neuronal development in infants, especially preterm, low birth, very low and extremely low birth weight infants as well as in young children up until the age of six. Administration of the swp according to the invention prevents and treats disorders associated with an immature or impaired enteric nervous system.
Nestec S.a.


Voice call management in a modular smartphone

In an embodiment of the disclosed principles, a modular portable device includes a first module acting as a traditional high-function phone or “smartphone” and a second module that adds enhanced functionality to the first module. When the modules are separated, they may operate independently of each other.
Motorola Mobility Llc

Method for preventing or treating functional gastrointestinal disorder by lactic acid bacterium

The present invention provides a method for preventing or treating a functional gastrointestinal disorder in a subject in need thereof that includes a step of administering a composition, wherein the composition includes an effective amount of lactobacillus plantarum subsp. Plantarum ps128 and a carrier.
National Yang-ming University

A pyrimidine derivative and a fatty acid source for use in the treatment of constipation

The invention relates to a combination of a pyrimidine derivative and a fatty acid source for use in the treatment of constipation, in particular in the treatment of constipation in patients suffering from gi disorders, neurological disorders, or psychiatric disorders. Advantageously, the combination comprises one or more vitamins or fibres..
N.v. Nutricia

Compositions for fecal floral transplantation and methods for making and using them and devices for delivering them

In alternative embodiments, the invention provides compositions, e.g., formulations, used for gastric, gastrointestinal and/or colonic treatments or lavage, e.g., orthostatic lavage, e.g., for inducing the purgation (e.g., cleansing) of a gastrointestinal (gi) tract, including a colon; and methods for making and using them. In alternative embodiments, compositions and methods of the invention are used for the stabilization, amelioration, treatment and/or prevention of constipation, for the treatment of abdominal pain, particularly non-specific abdominal pain, and diarrhea, including diarrhea caused by a drug side effect, a psychological condition, a disease or a condition such as crohn's disease, a poison, a toxin or an infection, e.g., a toxin-mediated traveler's diarrhea, or c.
Crestovo Llc

Modeling real capacity consumption changes using process-level data

A method includes receiving an expected growth rate for modeling future capacity utilization for a resource hosting a plurality of processes, each process being associated with a respective workload. The method also includes modifying, in a non-linear capacity utilization model for the resource, the respective workload for a particular process in the plurality of processes based on the expected growth rate, and, in response to modifying the respective workload, determining a change in total capacity utilization for the resource using the non-linear capacity utilization model.
Ca, Inc.

Monitoring immunotherapy of lewy body disease from constipation symptoms

The invention provides methods of monitoring immunotherapy directed against alpha-synuclein by comparing a subject's constipation symptoms before treatment and at one or more times during and/or after treatment. The immunotherapeutic regime can be monitored depending on the results of treatment..
Prothena Biosciences Limited

Enemas

The present invention relates to compositions for rectal use comprising honey in a weight percentage up to 95% w/w and glycerine in a weight percentage of between 2-40% w/w for the treatment of constipation in a subject in need thereof. The present invention also relates to a kit of parts comprising such a composition..
Aboca S.p.a. Societa' Agricola

Semiconductor device

According to the present invention, a grease layer having a grease as a constituent material is provided in a filling region lying between a heat dissipation surface that is a bottom surface of a heat dissipation material of a semiconductor module and a surface of a cooler. Further, a seal material is formed on the surface of the cooler and covers the entire side surface region of the grease layer without any gap.
Mitsubishi Electric Corporation

Novel compounds as rearranged during transfection (ret) inhibitors

This invention relates to novel compounds which are inhibitors of the rearranged during transfection (ret) kinase, to pharmaceutical compositions containing them, to processes for their preparation, and to their use in therapy, alone or in combination, for the normalization of gastrointestinal sensitivity, motility and/or secretion and/or abdominal disorders or diseases and/or treatment related to diseases related to ret dysfunction or where modulation of ret activity may have therapeutic benefit including but not limited to all classifications of irritable bowel syndrome (ibs) including diarrhea-predominant, constipation-predominant or alternating stool pattern, functional bloating, functional constipation, functional diarrhea, unspecified functional bowel disorder, functional abdominal pain syndrome, chronic idiopathic constipation, functional esophageal disorders, functional gastroduodenal disorders, functional anorectal pain, inflammatory bowel disease, proliferative diseases such as non-small cell lung cancer, hepatocellular carcinoma, colorectal cancer, medullary thyroid cancer, follicular thyroid cancer, anaplastic thyroid cancer, papillary thyroid cancer, brain tumors, peritoneal cavity cancer, solid tumors, other lung cancer, head and neck cancer, gliomas, neuroblastomas, von hippel-lindau syndrome and kidney tumors, breast cancer, fallopian tube cancer, ovarian cancer, transitional cell cancer, prostate cancer, cancer of the esophagus and gastroesophageal junction, biliary cancer, adenocarcinoma, and any malignancy with increased ret kinase activity.. .
Glaxosmithkline Intellectual Property Development Limited

Method and producing a model findings object

A possibility is to be created of achieving the diagnosis of objects which are difficult to access. To this end, an apparatus and a method are proposed for producing a model findings object, in which image data or images of an original findings object are provided.
Siemens Aktiengesellschaft

Babies' magic tea

A method of preparing tea comprising steps (a) selecting raw materials, wherein the raw materials include organic cumin seeds and organic funnel seeds; (b) washing the raw materials thoroughly; (c) sterilization of the raw materials via air-drying; (d) mixing a predetermined amount of organic funnel seeds and a predetermined amount of organic cumin seeds into a tea bags, wherein the tea bag is 1.5 g; (e) boiling 8 ounces of water, wherein the tea bag is added to the boiling water for 2 to 3 minutes; and (f) serving the tea to a baby at room temperature wherein the tea is intended for babies to reduce colic, gas, constipation, and acid reflux.. .

Storage controller, method, and storage system

A storage controller is coupled to a plurality of storage devices, the storage controller is configured to receive a first write request of data, determine a first time when the first write request is received, specify, based on the first time, a first storage device included in the plurality of storage devices, write the data into the first storage device, receive a read request for the data, determine a second time when the read request is received, specify a second storage device included in the plurality of storage devices, wherein, in anticipation of a second write request received at the second time, the processor specifies the second storage device based on the second time, determine whether the first storage device is identical to the second storage device, and not read the data from the first storage device when the first storage device is identical to the second storage device.. .
Fujitsu Limited

Opioid receptor antagonist for use in treating patients with severe constipation induced by high opiate dosage regimen

The present invention relates to a pharmaceutical composition comprising an opioid receptor antagonist, or a derivative or a pharmaceutically acceptable salt thereof, as an active substance, wherein the composition releases the active substance in a prolonged manner. The composition that is suitable for an administration period of at least twelve-hours for the treatment of severe opioid-induced constipation in patients receiving a daily dosage of opioid equivalent to at least 80 mg of morphine..
Develco Pharma Schweiz Ag

Composition of opioid receptor antagonists for use in treatment of constipation with highly increased whole gut transit time

The present invention relates to a composition comprising an opioid receptor antagonist in an extended release formulation for use in treating a patient with severe constipation characterised by a defined whole gut transit time.. .
Develco Pharma Schweiz Ag

Dosage of naloxone

The present invention relates to a pharmaceutical composition comprising a μ-receptor antagonist as an active substance, wherein the antagonist is prepared in an extended release formulation. The composition is intended for the treatment of patients with opioid-induced constipation, wherein the dosage of the μ-receptor agonist is independent of the opioid dosage.
Develco Pharma Schweiz Ag

Combined bingo and keno lottery game

The object of a combined bingo and keno game is to fill in a prearranged pattern of numbers as in a bingo game and the selection of lucky numbers as in a keno game. As these numbers are called at random, a secondary game can be played simultaneously.
Intralot, Inc.

Systems and methods of using an artificially intelligent database management system and interfaces for mobile, embedded, and other computing devices

The current disclosure generally relates to database management systems (dbmss) and may be generally directed to methods and systems of using artificial intelligence (i.e. Machine learning and/or anticipation functionalities, etc.) to learn a user's use of a dbms, store this “knowledge” in a knowledgebase, and anticipate the user's future operating intentions.

Systems and methods of using an artificially intelligent database management system and interfaces for mobile, embedded, and other computing devices

The current disclosure generally relates to database management systems (dbmss) and may be generally directed to methods and systems of using artificial intelligence (i.e. Machine learning and/or anticipation functionalities, etc.) to learn a user's use of a dbms, store this “knowledge” in a knowledgebase, and anticipate the user's future operating intentions.

Systems and methods of using an artificially intelligent database management system and interfaces for mobile, embedded, and other computing devices

The current disclosure generally relates to database management systems (dbmss) and may be generally directed to methods and systems of using artificial intelligence (i.e. Machine learning and/or anticipation functionalities, etc.) to learn a user's use of a dbms, store this “knowledge” in a knowledgebase, and anticipate the user's future operating intentions.

Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders

The invention provides novel guanylate cyclase-c agonist peptides and their use in the treatment of human diseases including gastrointestinal disorders, inflammation or cancer (e.g., a gastrointestinal cancer). The peptides can be administered either alone or in combination with an inhibitor of cgmp-dependent phosphodiesterase.
Synergy Pharmaceuticals, Inc.

Anthraquinone compounds and their uses

The present invention relates to a compound comprising a substituted or unsubstituted anthraquinone, or a salt or isomer thereof, for use in treating a disorder caused by or associated with dysfunctional ion channel activity. The invention finds utility in the treatment of disorders associated with smooth muscle tone and contraction, such as but not limited to partial hypertension; myocardial infarction; faecal incontinence; constipation; gastro oesophageal reflux; impaired gastrointestinal passage; urinary incontinence; erectile dysfunction; and asthma..
Dundalk Institute Of Technology

Social-driven precaching of accessible objects

A precaching system identifies an object, such as a media file, that a user accesses and then analyzes a social graph of the user to identify social graph contacts that may be interested in the object. Based on the content of the object—and the interests and connections of contacts in the social graph—the precaching system determines whether a particular contact in the user's social graph is likely also to access the object.
Cisco Technology, Inc.

Method of processing input/output in storage device and storage device and non-volatile memory device using the method

A method of processing input/output (i/o) in a storage device includes adjusting a read anticipation time based on a change of a resource management status related to operations of the storage device and performing an i/o processing operation at the storage device based on the adjusted read anticipation time. The i/o processing operation is performed to postpone an operation regarding a program command and perform a read command at higher priority than a write command at the storage device in a period from completion of a read operation at the storage device until the read anticipation time has elapsed..

System and multiple adjusting symbol changes during a wagering game

A gaming system performs a wagering game by determining an outcome, based at least in part, on one or more random elements. The wagering game uses a plurality of symbol bearing reels that includes at least one adjustable reel having an adjustable reel strip with one or more adjusting symbol positions thereon.
Wms Gaming Inc.

Method and system for anticipatory deployment of autonomously controlled vehicles

A method and system for management and anticipatory deployment of autonomously controlled vehicles are disclosed. According to one embodiment, a method may include calculating the geographic locations and periods of time where self-driving vehicles might experience the greatest probability of being requested to provide transportation services to passengers or cargo, and then communicating the resulting locations and times to self-driving vehicles, causing the vehicles to deploy themselves to those certain locations at those certain times, all prior to and in anticipation of specific requests being initiated by users or entities for such transport..
Tribal Rides, Inc.

Treatment of constipation-predominant irritable bowel syndrome

The invention provides methods for treating a patient with constipation-predominant irritable bowel syndrome by administering a therapeutically effective dose of linaclotide.. .
Forest Laboratories Holdings Limited

Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders

The invention provides novel guanylate cyclase-c agonist peptides and their use in the treatment of human diseases including gastrointestinal disorder, inflammation or cancer (e.g., a gastrointestinal cancer). The peptides can be administered either alone or in combination with an inhibitor of cgmp-dependent phosphodiesterase.
Synergy Pharmaceuticals, Inc.

I/o bandwidth reduction using storage-level common page information

I/o bandwidth reduction using storage-level common page information is implemented by a storage server, in response to receiving a request from a client for a page stored at a first virtual address, determining that the first virtual address maps to a page that is a duplicate of a page stored at a second virtual address or that the first and second virtual addresses map to a deduplicated page within a storage system, and transmitting metadata to the client mapping the first virtual address to a second virtual address that also maps to the deduplicated page. For one embodiment, the metadata is transmitted in anticipation of a request for the redundant/deduplicated page via the second virtual address.
Netapp, Inc.

Adaptive data streaming method with push messages control

There is provided methods for managing streaming over communication networks. Server and client devices share a push policy so that the client device may anticipate data pushes by the server.
Canon Kabushiki Kaisha

Use activated emergency alert for a medical device

An epinephrine auto-injector use activated device detects and responds to usage of the auto-injector. The resulting use activated device includes an actuator for manual generation of an injection force, as by a patient's hand, and a medicinal reservoir or vial for storing a quantity of medication for injection.

Formulations comprising polyethylene glycol

The present invention concerns a solid formulation for oral administration as a solid comprising polyethylene glycol and a further solid such as mannitol. The formulation may be used to prevent gastrointestinal disorders such as constipation in healthy subjects.
Norgine Bv

Vehicle speed control system and method

Embodiments of the present invention provide a vehicle speed control system operable to cause a vehicle to operate in accordance with a target speed value by controlling an amount of brake torque applied by a braking system and an amount of drive torque applied by a powertrain to one or more wheels of the vehicle, the system being operable to detect a leading wheel step event in which a leading wheel encounters an abrupt increase in surface gradient, the system being operable in dependence on the detection of a leading wheel step event to cause brake torque to be applied against drive torque in anticipation of a trailing wheel step event corresponding to the leading wheel step event, the system being operable to cause the application of brake torque at least until a trailing wheel has travelled a sufficient distance to reach the location at which a leading wheel experienced the leading wheel step event.. .

Method and system for queue length analysis

A system and method for analysing queues in frames of video enables operators to preferably draw three regions of interest overlaid upon the video as short, medium, and long queue regions that form a notional queue area within the video. The regions are drawn with knowledge of, or in anticipation of, foreground objects such as individuals and vehicles waiting for service in a queue.

Method and a system for determining an angular velocity in turning for a rotary wing aircraft

A method and a system for determining an angular velocity in turning for a rotary wing aircraft in order to make turns that are coordinated relative to the ground or else relative to the air and in order to manage the transition between ground coordination and air coordination while taking account of the wind to which said aircraft is subjected. Said method serving to determine an angular velocity in yaw by means of an anticipation value a and a correction value b on the basis in particular of speeds of advance of the aircraft relative to the ground vasol and relative to the air vaair, of its lateral acceleration gy and of its lateral load factor ny..

Natural herbal compositions for rapid removal of metabolic toxins in the body

The present invention provides a natural herbal composition for rapid removal of metabolic toxins in the body, to solve the problems of existing herbal compositions such as slow efficacy for such symptoms as constipation, bad breath, acnes caused by accumulated toxins in the body, side and toxic effects, etc. The natural herbal composition comprises the following ingredients (by mass): mangosteen extract, aloe extract, hot water extract of mixture of dandelion 1-30, angelica sinensis 1-20, polygonum multiflorum 1-30, cinnamomum cassia 3-16, rheum officinale 4-20, glycyrrhiza uralensis 3-10, panax notoginseng 3-10, atractylodes macrocephala 5-15, wherein the mass ratio of mangosteen fruit extract to aloe extract is 3:1-5, and the mass ratio of mangosteen and aloe extracts to the hot water extract is 2:1-5..

Legume/grain based food product with prebiotic/probiotic source

A minimally processed ready-to-eat legume/grain product is provided containing a significant amount of probiotic fiber and a probiotic source or is consumed with a probiotic source for the prevention and/or treatment of inflammatory chronic conditions such as inflammatory, autoimmune chronic conditions such as irritable bowel syndrome (ibs), digestive disorders such chronic constipation, gastric acid reflux, diabetes, heart disease, obesity, some type of cancer, malabsorptive disorders, eczema as well mental health disorders such as anxiety disorder. The present invention is suitable for men and woman of all ages..

Methods and compositions for the treatment of gastrointestinal disorders

Compositions and related methods for treating ibs and other gastrointestinal disorders and conditions (e.g., gastrointestinal motility disorders, functional gastrointestinal disorders, gastroesophageal reflux disease (gerd), duodenogastric reflux, crohn's disease, ulcerative colitis, inflammatory bowel disease, functional heartburn, dyspepsia (including functional dyspepsia or nonulcer dyspepsia), gastroparesis, chronic intestinal pseudo-obstruction (or colonic pseudoobstruction), and disorders and conditions associated with constipation, e.g., constipation associated with use of opiate pain killers, post-surgical constipation, and constipation associated with neuropathic disorders as well as other conditions and disorders are described. The compositions feature peptides that activate the guanylate cyclase c (gc-c) receptor..
Ironwood Pharmaceuticals, Inc.

Block-level predictive data migration

An apparatus for migrating data in a tiered storage architecture includes one or more processors and one or more memory devices coupled to the processors and storing instructions for execution by the processors. The instructions cause the one or more processors to: track temperature (i.e., frequency of access) of data blocks in a tiered storage architecture; generate heat maps indicating the temperature of the data blocks across different time intervals; process the heat maps using an image processing algorithm; compress the heat maps to reduce the size of the heat maps; compare the heat maps from the time intervals to identify temperature patterns occurring over time; predict, from the temperature patterns, when selected data blocks will change in temperature; and migrate the selected data blocks between tiers of the tiered storage architecture in anticipation of their changes in temperature..
International Business Machines Corporation

Methods of treating irritable bowel syndrome

The present invention provides a method for treating irritable bowel syndrome (ibs) in a subject in need thereof. The treatment can include administering about 550 mg of rifaximin three times per day and about 500 mg of neomycin two times per day for 14 days to the subject to treat the ibs.
Cedars-sinai Medical Center

System and controlling the power mode of operation of a memory device

A system and method are provided for controlling the power mode of operation of a memory device. The system includes a processing device for performing processing operations on data, and a memory controller associated with the memory device, the memory device being used to store data for access by the processing device.
Arm Limited

Content preview generation using social network analysis

Disclosed is a system and method for generating a preview of a digital content item using social network analysis. Members of a social network who acquire the digital content item may identify interesting portions of the digital content.
International Business Machines Corporation





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