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Pathologic

Pathologic-related patent applications - as published by the U.S. Patent and Trademark Office (USPTO).


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NEW Rapid n-glycan release from glycoproteins using immobilized glycosylase columns
June 22, 2017 - N°20170175099

N-glycosylation profiling of glycoprotein biotherapeutics is an essential step in each phase of product development in the biopharmaceutical industry. For example, during clone selection hundreds of clones should be analyzed quickly from limited amounts of samples. On the other hand, identification of disease related glycosylation alterations can serve as early indicators for various pathological conditions in the biomedical field. We ...
NEW Induction of arteriogenesis with an no (nitric oxide) donor
G. Pohl-boskamp Gmbh & Co. Kg
June 22, 2017 - N°20170172966

The present invention inter alia relates to a method of promoting collateral circulation comprising the step of exposing a subject to a therapeutically effective amount of an no donor wherein the therapeutically effective amount of the no donor promotes arteriogenesis sufficient to augment collateral circulation in a physiological or pathological condition.
Modular surgical simulation trainer and methods of use
Connecticut Children's Medical Center
June 15, 2017 - N°20170169733

The invention is directed to a modular surgical simulation trainer that makes use of anatomic surrogates placed within a housing to simulate a wide variety of various medical conditions including various laryngeal and tracheal pathological conditions. The anatomic surrogates exhibit tissue like properties and resemble healthy tissue or pathological tissue.
Pathologic Patent Pack
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Pathologic Patent Applications
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inventor
  • 207+ full patent PDF documents of Pathologic-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
Eye imaging device and method of use
Tsinghua University
June 15, 2017 - N°20170164830

In one aspect, disclosed herein are devices, systems, and methods for assessing human health states based on non-shadow imaging of sclera, or whites, of one or both eyes. In one aspect, the device is an on-body device. In one aspect, the system comprises a positioning aperture, an illuminating apparatus, an imaging apparatus, and/or a processing apparatus. In one aspect, ...
Use of 7-chloro-n,n,5-trimethyl-4-oxo-3-phenyl-3,5-dihydro-4h-pyridazino[4,5-b] indole-1-acetamide as a biomarker ...
Sanofi
June 08, 2017 - N°20170160287

Use of a radiolabelled form of 7-chloro-Λ/Λ,5-trimethyl-4-oxo-3-phenyl-3,5-dihydro-4/−/−pyridazino[4,5-b]indole-1-acetamide as a biomarker for the detection, in an individual, of pbr levels associated with normal and pathological conditions. Method for the detection of pbr levels associated with normal and pathological conditions. Diagnostic kit.
Detecting methylation in a subpopulation of genomic dna
Bio-rad Laboratories, Inc.
June 08, 2017 - N°20170159132

This invention provides methods of determining the biological, pathological, genetic, epigenetic or disease status in a biological sample by determining the methylation status of a subpopulation of genomic dna in the sample.
Pathologic Patent Pack
Download 207+ patent application PDFs
Pathologic Patent Applications
Download 207+ Pathologic-related PDFs
For professional research & prior art discovery
inventor
  • 207+ full patent PDF documents of Pathologic-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
Compounds binding to neuropathological aggregates
Technische Universität München
June 08, 2017 - N°20170157274

The present invention provides compounds binding to neuropathological aggregates of peptides or proteins, including aggregates such as neurofibrillary tangles (nfts), osynuclein aggregates and other amyloid aggregates. The compounds of the present invention are useful for the detection and/or diagnosis of disorders associated with such neuropathological aggregates. In further aspects, the invention provides diagnostic compositions comprising these compounds, and methods ...
Use of the chinese medicine composition and dianxianning in the preparation of a medicament for ...
Lanzhou University
June 08, 2017 - N°20170157192

Disclosed is a use of the chinese medicine composition and dianxianning in the preparation of a medicament for preventing or treating alzheimer's disease. As indicated by the experiments, the chinese medicine composition and dianxianning have a significant inhibiting effect on palsy phenotype in pathological models of animals with alzheimer's disease, and this indicates that the chinese medicine composition and dianxianning ...
Automated clinical evaluation of the eye
The Cleveland Clinic Foundation
June 08, 2017 - N°20170156582

Systems and methods are provided for evaluating an eye of a patient. A first imager interface receives a first image of at least a portion of the eye generated via a first imaging modality, and a second imager interface receives a second image of at least a portion of the eye generated via a second imaging modality. A first feature ...
Gak modulators as antivirals
Katholieke Universiteit Leuven
June 01, 2017 - N°20170152271

The present invention relates to the use of a class of novel isothiazolo[4,3-b]pyridine derivatives as well as to pharmaceutical compositions comprising one or more of said isothiazolo[4,3-b]pyridine derivatives and one or more pharmaceutically acceptable excipients as biologically active ingredients, more specifically as medicaments for the treatment of disorders and pathologic conditions such as viral diseases.
Methods of increasing muscle mass using non-toxic tetanus toxin c fragment (ttc)
Spherium Biomed, S.l.
June 01, 2017 - N°20170151316

The present disclosure relates to the use of the non-toxic proteolytic c fragment of tetanus toxin and plasmids encoding such protein fragment to increase muscle mass and/or muscle strength in a subject in need thereof. As such, methods of ameliorating the severity of a pathological condition characterized, at least in part, by a decreased amount, development, or metabolic activity ...
Human biosensors for heme binding
Spherium Biomed, S.l.
May 25, 2017 - N°20170146457

This invention provides biosensors, cell models, and methods of their use for monitoring heme and oxygen. Biosensors can include targeting domains, sensing domains and reporting domains. Biosensors can be introduced into cells reprogrammed to represent experimental or pathologic cells of interest. Model cells expressing the biosensors can be contacted with putative bioactive agents to determine possible activities.
Protein-based therapy and diagnosis of tau-mediated pathology in alzheimer's disease
Spherium Biomed, S.l.
May 25, 2017 - N°20170145082

The invention provides unique therapeutic and diagnostic antibodies, as well as their fragments, portions, derivatives, and variants thereof, that bind regions of the tau protein that contribute to the initiation and propagation of pathological tau-tau interactions, as well as methods of making them. The invention also relates to methods of using those antibodies for diagnostics, prevention, and treatment of alzheimer's ...
Pathologic Patent Pack
Download 207+ patent application PDFs
Pathologic Patent Applications
Download 207+ Pathologic-related PDFs
For professional research & prior art discovery
inventor
  • 207+ full patent PDF documents of Pathologic-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
Method of treating proliferative disorders and other pathological conditions mediated by bcr-abl, c-kit, ddr1, ddr2 ...
Spherium Biomed, S.l.
May 25, 2017 - N°20170143716

The present invention relates to a regimen for the administration of a pyrimidyl-aminobenzamide of formula 1 as defined herein for the treatment of proliferative disorders, particularly solid and liquid tumors, and other pathological conditions mediated by the bcr-abl oncoprotein, the cell transmembrane tyrosine kinase receptor c-kit, ddr1 (discoidin domain receptor 1), ddr2 (discoidin domain receptor 2) or pdgf-r (platelet derived growth factor receptor) ...
Method for regulating retinal endothelial cell viability
Spherium Biomed, S.l.
May 25, 2017 - N°20170143652

Here provided is a method for regulating retinal endothelial cell viability in a mammal by administering to the mammal a therapeutically effective amount of a quinic acid analog. The method may be applied to prevent, treat or cure pathological conditions of retinal endothelial cells associated with radiation retinopathy, diabetic retinopathy and chemotherapy for retinoblastoma.
Method and system for diagnosing disease and generating treatment recommendations
Global Gene Corporation Pte. Ltd.
May 18, 2017 - N°20170137968

The present invention relates generally to methods, algorithms, kits and systems for assessing health, diagnosing disease and generating recommendations using snv markers specific to a cohort. A genetic sample of an individual is assayed using a genotyping assay to identify at least one snv. The genotyping assay may be a computer analysis using a database, a nucleic acid microarray assay ...
Phosphospecific antibodies recognising tau
Katholieke Universiteit Leuven
May 18, 2017 - N°20170137502

The present invention relates to methods and compositions for the therapeutic and diagnostic use in the treatment of diseases and disorders which are caused by or associated with neurofibrillary tangles. In particular, the invention relates to antibodies, which specifically recognize and bind to phosphorylated pathological protein tau-conformers and to methods and compositions involving said antibodies for the therapeutic and diagnostic ...
Implantable cellular therapy device for treatment of graft versus host disease and tolerance induction
Viera Bioscience, Inc.
May 18, 2017 - N°20170136153

Implantable devices comprising a scaffold, cells, and/or therapeutic molecules are provided. Uses include inhibition of pathological immunity, elaboration of therapeutic growth factors, and immune augmentation. The implantable device may contain a porous substrate structure to which therapeutic cells are adherent, which can be implanted and explanted from a patient. In another embodiment, a medical device includes a porous substrate ...
Compositions and methods for treatment of microbial infections
Immunology Laboratories, Inc.
May 18, 2017 - N°20170136112

The present invention relates to methods and compositions for treatment of microbial infections and for the enhancement of resistance to infection. The invention comprises administration of an effective amount of a protein isolated from bacterial lysate compositions for the treatment of pathological compositions of microbial infections. The present invention can also be used to enhance the immune system to prevent ...
Method for preventing or treating ocular disorders
Zietchick Research Institute, Llc
May 18, 2017 - N°20170136093

A method for treating ocular-disorders which, involve angiogenesis or neovascularization as part of their pathologic process. These types of retinal disorders can be categorized as (a) retinal vascular disorders (such as diabetic retinopathy, retinal vein occlusions and retinopathy of prematurity), (b) subretinal neovascular disorders (such as neovascular age-related macular degeneration, ocular histoplasmosis, pathologic myopia) (c) intraocular tumors (such as ocular ...
Combinations of anti-her2 antibody-drug conjugate and chemotherapeutic agents, and methods of use
Genentech, Inc.
May 18, 2017 - N°20170136026

Combinations of the antibody-drug conjugate trastuzumab-mcc-dm1 and chemotherapeutic agents, including stereoisomers, geometric isomers, tautomers, solvates, metabolites and pharmaceutically acceptable salts thereof, are useful for inhibiting tumor cell growth, and for treating disorders such as cancer mediated by her2 and kdr (vegfr receptor 1). Methods of using such combinations for in vitro, in situ, and in vivo diagnosis, prevention or treatment of ...
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