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Organism

Organism-related patent applications - as published by the U.S. Patent and Trademark Office (USPTO).


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Transposon for genome manipulation
Agency For Science, Technology And Research
June 08, 2017 - N°20170159070

Disclosed is a vector comprising a piggybac like element (ple) transposon and/or transposase. Also disclosed are vectors comprising a combination of the vectors of the present disclosure, a transformation system comprising the vectors of the present disclosure, an oligonucleotide primer, methods of amplifying nucleotide sequences, methods of transforming a cell with a gene and a transgenic organism.
Method for using protein databases to identify microorganisms
Virgin Instruments Corporation
April 20, 2017 - N°20170108509

A method for identifying microorganisms by maldi-tof mass spectrometry includes acquiring a maldi mass spectrum of a microorganism, detecting peaks in the acquired maldi spectrum, generating a peak list comprising mass and intensity from the detected peaks in the acquired maldi spectrum, acquiring a database of protein sequences deduced from dna sequences for microorganisms, generating a sub-database of ribosomal proteins ...
Automated selection of microorganisms and identification using maldi
Bd Kiestra B.v.
April 06, 2017 - N°20170097368

A method and apparatus for locating and selecting a colony of microorganisms on a culture dish and identifying microorganisms in said selected colony using maldi. The method comprises the automated steps of locating and selecting a colony of microorganisms on a culture dish; obtaining a sample of said selected colony of microorganisms; depositing at least some of said sample of ...
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Novel ecdysone receptor/invertebrate retinoid x receptor-based inducible gene expression system
Intrexon Corporation
April 06, 2017 - N°20170096672

This invention relates to the field of biotechnology or genetic engineering. Specifically, this invention relates to the field of gene expression. More specifically, this invention relates to a novel ecdysone receptor/invertebrate retinoid x receptor-based inducible gene expression system and methods of modulating gene expression in a host cell for applications such as gene therapy, large-scale production of proteins and ...
Transgenic nuclease systems and methods
Agenovir Corporation
April 06, 2017 - N°20170096649

The invention provides transgenic organisms that include a transgene that codes for a product that can be used to digest foreign nucleic acid. The transgene can code for a targeting nuclease, a guide sequence, or other components of a guided nuclease system. Expression of the transgene causes the organism to express an active targeting nuclease that targets and digests foreign ...
Compositions and methods of engineered crispr-cas9 systems using split-nexus cas9-associated polynucleotides
Caribou Biosciences, Inc.
February 16, 2017 - N°20170044508

The present specification discloses engineered type ii crispr-cas9 systems comprising split-nexus cas9-associated polynucleotides (sn-caspns), including systems comprising three split-nexus cas9-associated polynucleotides (sn1-caspn/sn2-caspn/sn3-caspn) and systems comprising two split-nexus cas9-associated polynucleotides (sn1-caspn/5n2-caspn). Together with a cas9 protein, the sn-caspns facilitate site-specific modifications, including cleavage and mutagenesis, of a target polynucleotide in ...
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Method for the production of multiple-unsaturated fatty acids in transgenic organisms
Basf Plant Science Gmbh
January 19, 2017 - N°20170016015

The present invention relates to a process for the production of polyunsaturated fatty acids in an organism by introducing, into the organism, nucleic acids which encode polypeptides with Δ5-elongase activity. Advantageously, these nucleic acids can be expressed in the organism together with further nucleic acids which encode polypeptides of the biosynthesis of the fatty acid or lipid metabolism. Especially ...
Synthetic genes and genetic constructs
Commonwealth Scientific And Industrial Research Organisation
January 05, 2017 - N°20170002379

The present invention relates generally to synthetic genes for modifying endogenous gene expression in a cell, tissue or organ of a transgenic organism, in particular a transgenic animal or plant. More particularly, the present invention provides novel synthetic genes and genetic constructs which are capable of repressing delaying or otherwise reducing the expression of an endogenous gene or a target ...
Systems and methods for identifying microorganisms
Seven Bridges Genomics Inc.
December 15, 2016 - N°20160364523

The invention provides methods for identifying a microorganism by aligning sequence reads to a graph, such as a directed acyclic graph (dag), that contains condensed sequence information of a conserved region from multiple known microorganisms. The dag can be constructed by obtaining sequence information of known reference microorganisms. The dag also includes the identities of the known microorganisms that correspond ...
Crispr-cas compositions and methods
Caribou Biosciences, Inc.
December 15, 2016 - N°20160362667

Class 2 crispr-cas nucleoprotein complexes are disclosed comprising a class 2 crispr-cas protein, a crispr-cas associated polynucleotide lacking a spacer element (caspn), and a distinct spacer element sequence polynucleotide (sespn) comprising a target nucleic acid binding sequence. These complexes are capable of site-directed binding to a target nucleic acid complementary to the target nucleic acid binding sequence of the sespn. The class 2 ...
Novel reporter constructs for compound screening
Koch Biological Solutions, Llc
December 01, 2016 - N°20160349243

The instant description provides reporter constructs, transgenic cells, and transgenic organisms and methods for identifying agents that can regulate gene expression and improve plant performance and yield. Compounds that increase plant performance or yield are identified by contacting a test compound with a plant cell that comprises a target promoter sequence operably linked to a polynucleotide sequence encoding a dna ...
Processes for producing polyunsaturated fatty acids in transgenic organisms
Basf Plant Science Gmbh
October 20, 2016 - N°20160304841

The present invention relates to polynucleotides from ostreococcus lucimarinus which code for desaturases and elongases and which can be employed for the recombinant production of polyunsaturated fatty acids. The invention furthermore relates to vectors, host cells and transgenic nonhuman organisms which comprise the polynucleotides, and to the polypeptides encoded by the polynucleotides. Finally, the invention also relates to production processes ...
Acyltransferases and uses thereof in fatty acid production
Basf Plant Science Company Gmbh
September 22, 2016 - N°20160272951

The present invention relates to the recombinant manufacture of polyunsaturated fatty acids. Specifically, it relates to acyltransferase polypeptides, polynucleotides encoding said acyltransferases as well as vectors, host cells, non-human transgenic organisms containing said polynucleotides. Moreover, the present invention contemplates methods for the manufacture of polyunsaturated fatty acids as well as oils obtained by such methods.
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Novel substitution mutant receptors and their use in a nuclear receptor-based inducible gene expression system
Intrexon Corporation
September 08, 2016 - N°20160257964

This invention relates to the field of biotechnology or genetic engineering. Specifically, this invention relates to the field of gene expression. More specifically, this invention relates to novel substitution mutant receptors and their use in a group h nuclear receptor-based inducible gene expression system and methods of modulating the expression of a gene in a host cell for applications such ...
Novel reporter constructs for compound screening
Koch Biological Solutions, Llc
July 14, 2016 - N°20160201146

The instant description provides reporter constructs, transgenic cells, and transgenic organisms and methods for identifying agents that can regulate gene expression and improve plant performance and yield. Compounds that increase plant performance or yield are identified by contacting a test compound with a plant cell that comprises a target promoter sequence operably linked to a polynucleotide sequence encoding a dna ...
Compositions and methods for lowering counts of pathogenic microorganisms in food products
Isoage Technologies Llc
June 16, 2016 - N°20160165908

Compositions and methods for lowering counts of pathogenic microorganisms in food products such as ready to eat meat and poultry products are disclosed. In various embodiments, the compositions and methods comprise antimicrobial compositions with one or more essential oils added.
Apparatus and method for detecting and identifying microorganisms
The Board Of Trustees Of The University Of Illinois
May 05, 2016 - N°20160122698

The present invention is an apparatus for detecting the presence, quantity and identity of one or more microorganisms in a sample and a method for using the same. The apparatus is composed of one or more chambers and a sensing element for sensing microorganisms. In particular embodiments, the sensing element is an array of chemoresponsive dyes deposited on a substrate ...
Composition and kits for inhibition of pathogenic microbial infection and methods of using the same
Rochal Industries, Llp
April 07, 2016 - N°20160095876

Antimicrobial polymer coating formulations are prepared that protect biological surfaces by treating, reducing, ameliorating, preventing or inhibiting pathogenic microorganism ingress to a human or animal host, reducing the potential for infection, particularly by necrotizing fasciitis originating microorganisms, through use of an polymer coating barrier containing antimicrobial agents that facilitates sustained release of biocidal agents active against such opportunistic microorganisms. Such ...
Boron-containing diacylhydrazine compounds
Rochal Industries, Llp
March 24, 2016 - N°20160083403

And the pharmaceutically acceptable salts and solvates thereof, wherein a, r4, and r5 are defined as set forth in the specification. The present disclosure also provides the use of boron-containing diacylhydrazines is ecdysone receptor-based inducible gene expression systems. Thus, the present disclosure is useful for applications such as gene therapy, treatment of disease, large scale production of proteins and antibodies, ...
Acyltransferases and uses thereof in fatty acid production
Basf Plant Science Company Gmbh
March 03, 2016 - N°20160060606

The present invention pertains to the recombinant manufacture of polyunsaturated fatty acids. Specifically, it relates to acyltransferase polypeptides, polynucleotides encoding said acyltransferases as well as vectors, host cells, non-human transgenic organisms containing said polynucleotides. Moreover, the present invention contemplates methods for the manufacture of polyunsaturated fatty acids as well as oils obtained by such methods.
Methods for microorganism detection and identification
Immunotrex Biologics Inc.
January 21, 2016 - N°20160017407

Methods for detecting and identifying microorganisms in a biologic sample are provided. The methods utilize identifying rrna from microorganisms to both show the presence and identity for the majority of infectious agents present in clinical samples. The methods are preferably adapted for use in a clinical setting.
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