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 Processes for producing polyunsaturated fatty acids in transgenic organisms patent thumbnailProcesses for producing polyunsaturated fatty acids in transgenic organisms
The present invention relates to polynucleotides from ostreococcus lucimarinus which code for desaturases and elongases and which can be employed for the recombinant production of polyunsaturated fatty acids. The invention furthermore relates to vectors, host cells and transgenic nonhuman organisms which comprise the polynucleotides, and to the polypeptides encoded by the polynucleotides.
Basf Plant Science Gmbh


 Acyltransferases and uses thereof in fatty acid production patent thumbnailAcyltransferases and uses thereof in fatty acid production
The present invention relates to the recombinant manufacture of polyunsaturated fatty acids. Specifically, it relates to acyltransferase polypeptides, polynucleotides encoding said acyltransferases as well as vectors, host cells, non-human transgenic organisms containing said polynucleotides.
Basf Plant Science Company Gmbh


 Binding-triggered transcriptional switches and methods of use thereof patent thumbnailBinding-triggered transcriptional switches and methods of use thereof
The present disclosure provides binding-triggered transcriptional switch polypeptides, nucleic acids comprising nucleotide sequences encoding the binding-triggered transcriptional switch polypeptides, and host cells genetically modified with the nucleic acids. The present disclosure also provides chimeric notch receptor polypeptides, nucleic acids comprising nucleotide sequences encoding the chimeric notch receptor polypeptides, and host cells transduced and/or genetically modified with the nucleic acids.
The Regents Of The University Of California


 Novel substitution mutant receptors and their use in a nuclear receptor-based inducible gene expression system patent thumbnailNovel substitution mutant receptors and their use in a nuclear receptor-based inducible gene expression system
This invention relates to the field of biotechnology or genetic engineering. Specifically, this invention relates to the field of gene expression.
Intrexon Corporation


 Novel reporter constructs for compound screening patent thumbnailNovel reporter constructs for compound screening
The instant description provides reporter constructs, transgenic cells, and transgenic organisms and methods for identifying agents that can regulate gene expression and improve plant performance and yield. Compounds that increase plant performance or yield are identified by contacting a test compound with a plant cell that comprises a target promoter sequence operably linked to a polynucleotide sequence encoding a dna sequence-specific transactivator, and a reporter polynucleotide that is operably linked to a promoter sequence that is recognized by the dna sequence-specific transactivator.
Koch Biological Solutions, Llc


 Compositions and methods for lowering counts of pathogenic microorganisms in food products patent thumbnailCompositions and methods for lowering counts of pathogenic microorganisms in food products
Compositions and methods for lowering counts of pathogenic microorganisms in food products such as ready to eat meat and poultry products are disclosed. In various embodiments, the compositions and methods comprise antimicrobial compositions with one or more essential oils added..
Isoage Technologies Llc


 Apparatus and  detecting and identifying microorganisms patent thumbnailApparatus and detecting and identifying microorganisms
The present invention is an apparatus for detecting the presence, quantity and identity of one or more microorganisms in a sample and a method for using the same. The apparatus is composed of one or more chambers and a sensing element for sensing microorganisms.
The Board Of Trustees Of The University Of Illinois


 Composition and kits for inhibition of pathogenic microbial infection and methods of using the same patent thumbnailComposition and kits for inhibition of pathogenic microbial infection and methods of using the same
Antimicrobial polymer coating formulations are prepared that protect biological surfaces by treating, reducing, ameliorating, preventing or inhibiting pathogenic microorganism ingress to a human or animal host, reducing the potential for infection, particularly by necrotizing fasciitis originating microorganisms, through use of an polymer coating barrier containing antimicrobial agents that facilitates sustained release of biocidal agents active against such opportunistic microorganisms. Such formulations are effective for inhibiting microbial ingress pertaining to soft tissue and skin tears, abrasions, punctures and surgical wounds, and can be used as in water environments and as a skin protectant sunscreen and insect repellent..
Rochal Industries, Llp


 Boron-containing diacylhydrazine compounds patent thumbnailBoron-containing diacylhydrazine compounds
And the pharmaceutically acceptable salts and solvates thereof, wherein a, r4, and r5 are defined as set forth in the specification. The present disclosure also provides the use of boron-containing diacylhydrazines is ecdysone receptor-based inducible gene expression systems.

 Acyltransferases and uses thereof in fatty acid production patent thumbnailAcyltransferases and uses thereof in fatty acid production
The present invention pertains to the recombinant manufacture of polyunsaturated fatty acids. Specifically, it relates to acyltransferase polypeptides, polynucleotides encoding said acyltransferases as well as vectors, host cells, non-human transgenic organisms containing said polynucleotides.
Basf Plant Science Company Gmbh


Methods for microorganism detection and identification

Methods for detecting and identifying microorganisms in a biologic sample are provided. The methods utilize identifying rrna from microorganisms to both show the presence and identity for the majority of infectious agents present in clinical samples.
Immunotrex Biologics Inc.

Bacillus subtilis isolate from corn and extracts that inhibit the growth of undesirable microorganisms in food products

Biologically pure cultures of bacillus subtilis maseca-1 strain were isolated from the pericarp of nixtamalized corn. The bacillus maseca-1 strain was characterized and found to produce peptides and/or other compounds that have antimicrobial activity.
Investigacion Tecnica Avanzada, S.a. De C.v.

Methods for separation and characterization of microorganisms using identifier agents

The present invention is directed to a method for separating, characterizing and/or identifying microorganisms in a test sample. The method of the invention comprises an optional lysis step for lysing non-microorganism cells that may be present in a test sample, followed by a subsequent separation step.
Biomerieux, Inc.

Stable transformation of a population and a biocontainment using haploinsufficiency and underdominance principles

The present invention relates to a method for reducing the competitive fitness of an organism hemizygous for a transgenic locus compared to the organism homozygous for the transgenic locus comprising the steps of: (a) reducing the expression of a haploinsufficient gene in the organism, wherein said reduction is conveyed by a transgenic locus in the organism; and (b) rescuing the reduced expression in the organism, wherein said rescue is conveyed by the same transgenic locus in the organism, yielding an organism which is less competitively fit if hemizygous for the transgenic locus than if homozygous for the transgenic locus. The present invention also relates to a method for decreasing the introgression of a transgenic locus in an organism into a population of otherwise interfertile sexually reproducing organisms comprising the steps of: (a) reducing the expression of a haploinsufficient gene in the organism, wherein said reduction is conveyed by a transgenic locus in the organism; (b) rescuing the reduced expression in the organism, wherein said rescue is conveyed by the same transgenic locus in the organism, and (c) using a transgenic organism obtained in step (b) in an environment comprising otherwise interfertile sexually reproducing wildtype individuals of the organism, wherein the competitive fitness of hemizygous progeny is reduced, thereby decreasing the rate of sexually reproduction and/or viability and/or the competitive fitness of hemizygous progeny.
Max-planck-gesellschaft Zur FÖrderung Der Wissenschaften E.v.

Preparation of 7-dehydrocholesterol and/or the biosynthetic intermediates and/or secondary products thereof in transgenic organisms

The present invention relates to a method for preparing 7-dehydrocholesterol and/or the biosynthetic intermediates and/or secondary products thereof by culturing organisms, in particular yeasts. Furthermore, the invention relates to the preparation of the nucleic acid constructs required for preparing the genetically modified organisms and to said genetically modified organisms, in particular yeasts, themselves..
Organobalance Gmbh

Designer photoautotrophic and hydrogenotrophic production of alcohols and biodiesel

Designer calvin-cycle-channeled and hydrogenotrophic biofuel-production pathways, the associated designer genes and designer transgenic organisms for autotrophic production of alcohols and biodiesel from carbon dioxide, hydrogen, and/or water are disclosed. The alcohols include methanol, ethanol, propanol, 1-butanol, 2-methyl-1-butanol, isobutanol, 3-methyl-1-butanol, 1-hexanol, 1-octanol, 1-pentanol, 1-heptanol, 3-methyl-1-pentanol, 4-methyl-1-hexanol, 5-methyl-1-heptanol, 4-methyl-1-pentanol, 5-methyl-1-hexanol, and 6-methyl-1-heptanol.

Methods of producing lipids

The present invention relates to methods of producing lipids. In particular, the present invention relates to methods of increasing the level of one or more non-polar lipids and/or the total non-polar lipid content in a transgenic organism or part thereof.
Commonwealth Scientific And Industrial Research Organisation

Methods and kits for identifying microorganisms in a sample

Disclosed herein are compositions with uniquely designed oligonucleotide primers for identifying a plurality of microorganisms in a sample, and improved methods for detection of microbial populations from diverse biological and environmental samples.. .
Genewiz Inc.

Synthetic genes and genetic constructs

The present invention relates generally to synthetic genes for modifying endogenous gene expression in a cell, tissue or organ of a transgenic organism, in particular a transgenic animal or plant. More particularly, the present invention provides novel synthetic genes and genetic constructs which are capable of repressing delaying or otherwise reducing the expression of an endogenous gene or a target gene in an organism when introduced thereto..
Commonwealth Scientific And Industrial Research Organisation

Boron-containing diacylhydrazines

And the pharmaceutically acceptable salts and solvates thereof, wherein r1, r2, r3, r4, and r5 are defined as set forth in the specification. The present disclosure also provides the use of boron-containing diacylhydrazines is ecdysone receptor-based inducible gene expression systems.

Isolated genes and transgenic organisms for producing biofuels

Methods for the production of lipids and biofuels with a culture of candidatus microthrix spp. Grown on a medium such as wastewater or sewage sludge are provided.
The Translational Genomics Research Institute

Transgenic biosensor

Systems and methods relate to transgenic organisms and their use as biosensors are described. In some embodiments, the systems and methods include a first population of transgenic organisms that includes a first constitutively expressed reporter gene, and a first transgene that includes a first inducible promoter from a response pathway gene, wherein the first inducible promoter is coupled to a first reporter gene.

Recombinant dna for gene suppression

Anti-sense-oriented rna gene suppression agents in the form of a loop of anti-sense-oriented rna is produced in cells of transgenic organisms, e.g. Plants, by transcription from a recombinant dna construct which comprises in 5′ to 3′ order a promoter element operably linked to an anti-sense-oriented dna element and a complementary dna element..
Monsanto Technology Llc

Oil globule protein and uses thereof

An isolated novel oil globule protein encoded by a polynucleotide sequence is provided together with a composition which includes the isolated protein. A transgenic organism transformed by a polynucleotide encoding a protein which at least partially comprises the amino acid sequence of the novel oil globule protein is also provided.
Yeda Research And Development Co. Ltd.

Unique modular vector design

The current invention provides a modular vector system that enables the insertion of gene expression cassettes in a recursive directional stacking fashion by rare restriction sites which requires only one type of vector. The invention also provides dna molecules, compositions, and transgenic organisms, plants, plant tissues, plant seeds, and cells comprising recombined restriction sites for rare restriction enzymes..
Monsanto Technology Llc

Chimeric retinoid x receptors and their use in a novel ecdysone receptor-based inducible gene expression system

This invention relates to the field of biotechnology or genetic engineering. Specifically, this invention relates to the field of gene expression.
Intrexon Corporation

Acyl-acp thioesterase genes and uses therefor

The present invention provides novel genes encoding class ii acyl-acp thioesterases and variants thereof that are active on c8, c10, c12, c14, c16, and c18 acyl-acp substrates. The thioesterases can be introduced into transgenic organisms, including microorganisms and photosynthetic organisms, for producing fatty acids and fatty acid products..
Synthetic Genomics, Inc.

Methods, systems, and devices for detecting and identifying microorganisms in microbiological culture samples

Provided herein are methods, systems, and devices for detecting and/or identifying one or more specific microorganisms in a culture sample. Indicator particles, such as surface enhanced raman spectroscopy (sers)-active nanoparticles, each having associated therewith one or more specific binding members having an affinity for the one or more microorganisms of interest, can form a complex with specific microorganisms in the culture sample.
Becton Dickinson And Company

Chiral diacylhydrazine ligands for modulating the expression of exogenous genes via an ecdysone receptor complex

The present invention provides diacylhydrazine ligands and chiral diacylhydrazine ligands for use with ecdysone receptor-based inducible gene expression systems. Thus, the present invention is useful for applications such as gene therapy, large scale production of proteins and antibodies, cell-based screening assays, functional genomics, proteomics, metabolomics, and regulation of traits in transgenic organisms, where control of gene expression levels is desirable.
Intrexon Corporation

Automated selection of microorganisms and identification using maldi

A method and apparatus for locating and selecting a colony of microorganisms on a culture dish and identifying microorganisms in said selected colony using maldi. The method comprises the automated steps of locating and selecting a colony of microorganisms on a culture dish; obtaining a sample of said selected colony of microorganisms; depositing at least some of said sample of said selected colony of microorganisms on a target plate; and transferring said target plate with said sample in an apparatus for performing maldi for identification of said sample of said selected colony of microorganisms.
Bd Kiestra B.v.

Diterpene synthases and producing diterpenoids

Provided herein are diterpene synthases (ditps) and methods for producing diterpenoids. Also provided herein are nucleic acid sequences encoding ditps, ditps amino acid sequences, ditps proteins, vectors, cells, transgenic organisms, uses, compositions, methods, processes, and kits thereof..

Biopreservation methods for beverages and other foods

Several embodiments of the present invention relate generally to the use of non-pathogenic microorganisms to prevent the growth and/or activity of pathogenic microorganisms in food products. More specifically, several embodiments relate to manipulation of the ph of low acid foods by non-pathogenic microorganisms to generate a local environment that is adverse to pathogenic microorganisms..
Starbucks Corporation D/b/a Starbucks Coffee Company

Spectroscopic means and methods for identifying microorganisms in culture

A spectroscopic method for spectroscopic detection and identification of bacteria in culture is disclosed. The method incorporates construction of at least one data set, which may be a spectrum, interference pattern, or scattering pattern, from a cultured sample suspected of containing said bacteria.
Opticul Diagnostics Inc.

Apparatus and detecting and identifying microorganisms

The present invention is an apparatus for detecting the presence, quantity and identity of one or more microorganisms in a sample and a method for using the same. The apparatus is composed of one or more chambers and a sensing element for sensing microorganisms.
The Board Of Trustees Of The University Of Illinois

Method for identifying microorganisms by mass spectrometry

A method of identifying a microorganism by mass spectrometry, including acquiring at least one mass spectrum of said microorganism; for each acquired mass spectrum: detecting peaks of the spectrum in a predetermined mass range; generating a list of peaks identifying at most one peak in each interval of a predetermined subdivision of the range of mass-to-charge ratios, the width of the intervals of the subdivision logarithmically increasing along with the mass-to-charge ratio, and analyzing the list(s) of peaks obtained according to a knowledge base of previously-identified microorganisms and/or types of microorganisms.. .

Method for identifying microorganisms via mass spectrometry and score normalization

Where: m is the distance calculated for the reference microorganism; n(m. .
μ,σ) is the value, for m, of a random variable modeling the distance between a reference microorganism to be identified and the reference microorganism, when the microorganism is the reference microorganism; n(m

Desaturases and process for the production of polyunsaturated fatty acids in transgenic organisms

The present invention relates to polynucleotides from cochliobolus heterostrophus c5, cyanothece sp. Ccy0110, mycocentrospora acerin and hyaloperonospora parasitica, which code for desaturases and which can be employed for the recombinant production of polyunsaturated fatty acids.

Mutant receptors and their use in a nuclear receptor-based inducible gene expression system

This invention relates to the field of biotechnology or genetic engineering. Specifically, this invention relates to the field of gene expression.

Boron-containing diacylhydrazines

And the pharmaceutically acceptable salts and solvates thereof, wherein r1, r2, r3, r4, and r5 are defined as set forth in the specification. The present disclosure also provides the use of boron-containing diacylhydrazines is ecdysone receptor-based inducible gene expression systems.

Methods for producing cinnamolide and/or drimendiol

Described is a nucleic acid sequence isolated from persicaria hydropiper and encoding a drimenol oxidase protein, expression vectors comprising such nucleic acid sequence, chimeric genes comprising such nucleic acid sequence, host cells or host organisms altered to harbour the drimenol oxidase nucleic acid sequence, and the drimenol oxidase protein itself. Methods for producing cinnamolide and/or drimendiol and/or enhanced levels of cinnamolide and/or drimendiol, in a cell or organism harbouring such nucleic acid sequence are provided.

Plants expressing delta6-desaturase genes and oils from these plants containing pufas and producing unsaturated fatty acids

The present invention relates to an improved process for the preparation of unsaturated fatty acids and to a process for the preparation of triglycerides with an increased content of unsaturated fatty acids. The invention relates to the generation of transgenic microorganism, with an increased content of fatty acids, oils or lipids with Δ6 double bonds owing to the expression of a moss Δ6-desaturase.

Nuclease fusion protein and uses thereof

The present invention is concerned with nuclease fusion proteins and various uses thereof. Specifically, it relates to a polynucleotide encoding a polypeptide comprising (i) a first module comprising at least a first dna binding domain derived from a homing endonuclease, (ii) a linker, and (iii) a second module comprising at least a second dna binding domain and a cleavage domain derived from a restriction endonuclease, wherein said polypeptide functionally interacts only with dna comprising a dna recognition site for the first dna binding domain and a dna recognition site for the second dna binding domain, and wherein said cleavage domain cleaves dna within a specific dna cleavage site upon binding of the polypeptide.

Acyl-coa: diacylglycerol acyltransferase 1-like gene (ptdgat1) and uses thereof

An isolated protein which is at least partially encoded by a polynucleotide sequence encoding a novel acyl-coa: diacylglycerol acyltransferase 1—like gene (ptdgat1) from the diatom phaeodactylum tricomutum is provided together with a composition which includes the isolated protein and a transgenic organism transformed by a polynucleotide encoding same. The invention also provides a method for producing or enhancing the production of oil or triacylglycerols with high saturated fatty acids content..

Control of gene expression

The present invention relates generally to a method of modifying gene expression and to synthetic genes for modifying endogenous gene expression in a cell, tissue or organ of a transgenic organism, in particular a transgenic animal or plant. More particularly, the present invention utilizes recombinant dna technology to post-transcriptionally modify or modulate the expression of a target gene in a cell, tissue organ or whole organism, thereby producing novel phenotypes.

Methods for separation, characterization and/or identification of microorganisms using spectroscopy

The present invention is directed to a method for separating, characterizing and/or identifying microorganisms in a test sample. The method of the invention comprises an optional lysis step for lysing non-microorganism cells that may be present in a test sample, followed by a subsequent separation step.

Enhanced zein reduction in transgenic corn seed

Anti-sense-oriented rna gene suppression agents in the form of a loop of anti-sense-oriented rna is produced in cells of transgenic organisms, e.g. Plants, by transcription from a recombinant dna construct that comprises in 5′ to 3′ order a promoter element operably linked to more than one anti-sense-oriented dna element and one or more complementary dna elements..

Methods for microorganism detection and identification

Methods for detecting and identifying microorganisms in a biologic sample are provided. The methods utilize identifying rrna from microorganisms to both show the presence and identity for the majority of infectious agents present in clinical samples.

Manipulation of genes of the mevalonate and isoprenoid pathways to create novel traits in transgenic organisms

Disclosed are the uses of specific genes of the mevalonate and isoprenoid biosynthetic pathways, and of inactive gene sites (the pseudogene) to (1) enhance biosynthesis of isopentenyl diphosphate, dimethylallyl diphosphate and isoprenoid pathway derived products in the plastids of transgenic plants and microalgae, (2) create novel antibiotic resistant transgenic plants and microalgae, and (3) create a novel selection system and/or targeting sites for mediating the insertion of genetic material into plant and microalgae plastids. The specific polynucleotides to be used, solely or in any combination thereof, are publicly available from genebank and contain open reading frames having sequences that upon expression will produce active proteins with the following enzyme activities: (a) acetoacetyl coa thiolase (ec 2.3.1.9), (b) 3-hydroxy-3-methylglutaryl-coenzyme a (hmg-coa) synthase (ec 4.1.3.5), (c) hmg-coa reductase (ec 1.1.1.34), (d) mevalonate kinase (ec 2.7.1.36), (e) phosphomevalonate kinase (ec 2.7.4.2), (f) mevalonate diphosphate decarboxylase (ec 4.1.1.33), (g) isopentenyl diphosphate (ipp) isomerase (ec 5.3.3.2), and (h) phytoene synthase (ec 2.5.1.32)..

Method for the production of polyunsaturated fatty acids

The present invention relates to a process for producing polyunsaturated fatty acids in an organism by introducing nucleic acids into the organism which code for polypeptides having acyl-coa:lysophospholipid a cyltransferase activity. Advantageously, these nucleic acid sequences may, if appropriate together with further nucleic acid sequences coding for biosynthesis polypeptides of the fatty acid or lipid metabolism, be expressed in the transgenic organism.





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This listing is a sample listing of patent applications related to Organism for is only meant as a recent sample of applications filed, not a comprehensive history. There may be associated servicemarks and trademarks related to these patents. Please check with patent attorney if you need further assistance or plan to use for business purposes. This patent data is also published to the public by the USPTO and available for free on their website. Note that there may be alternative spellings for Organism with additional patents listed. Browse our RSS directory or Search for other possible listings.


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