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 Queuing actions received while a client device is offline for execution when connectivity is restored between the client device and a digital magazine server patent thumbnailnew patent Queuing actions received while a client device is offline for execution when connectivity is restored between the client device and a digital magazine server
A digital magazine application associated with a digital magazine server executes on a client device and allows a user to interact with content from the digital magazine server even when the client device is unable to communicate with the digital magazine server. When the application detects loss of communication with the digital magazine server, interactions received by the application after the loss of communication has been detected are stored in a queue on the client device.
Flipboard, Inc.


 Pharmaceutical compositions comprising an antipsychotic drug and a vmat2 inhibitor and uses thereof patent thumbnailPharmaceutical compositions comprising an antipsychotic drug and a vmat2 inhibitor and uses thereof
New methods of treating schizophrenia and schizoaffective disorder by administration of pharmaceutical compositions comprising an antipsychotic compound and a vmat2 inhibitor to a subject in need thereof are provided.. .
Neurocrine Biosciences, Inc.


 Real-time settlement of securities trades over append-only ledgers patent thumbnailReal-time settlement of securities trades over append-only ledgers
Various of the disclosed embodiments concern systems and methods for expediting the settlement of securities traded on an exchange. A settlement system can generate electronic records of financial transactions by bundling a trade report, clearing instructions, etc., into a cryptographic ledger.
Domus Tower, Inc.


 Cathode control multi-cathode distributed x-ray apparatus and ct device having said apparatus patent thumbnailCathode control multi-cathode distributed x-ray apparatus and ct device having said apparatus
This invention relates to an apparatus producing distributed x-ray, and in particular to a cathode control multi-cathode distributed x-ray apparatus, which produces x-ray that changes focal position in a predetermined order by arranging multiple independent hot cathodes and controlling cathodes in an x-ray source device, and a ct device having said x-ray apparatus.. .
Tsinghua University


 Coding of significance maps and transform coefficient blocks patent thumbnailCoding of significance maps and transform coefficient blocks
A higher coding efficiency for coding a significance map indicating positions of significant transform coefficients within a transform coefficient block is achieved by the scan order by which the sequentially extracted syntax elements indicating, for associated positions within the transform coefficient block, as to whether at the respective position a significant or insignificant transform coefficient is situated, are sequentially associated to the positions of the transform coefficient block, among the positions of the transform coefficient block depends on the positions of the significant transform coefficients indicated by previously associated syntax elements. Alternatively, the first-type elements may be context-adaptively entropy decoded using contexts which are individually selected for each of the syntax elements dependent on a number of significant transform coefficients in a neighborhood of the respective syntax element, indicated as being significant by any of the preceding syntax elements..
Ge Video Compression, Llc


 Music dissection and puzzle patent thumbnailMusic dissection and puzzle
A musical composition in broken down by instrument or channels within the composition. The composition is further broken down by time period.

 Coding of significance maps and transform coefficient blocks patent thumbnailCoding of significance maps and transform coefficient blocks
A higher coding efficiency for coding a significance map indicating positions of significant transform coefficients within a transform coefficient block is achieved by the scan order by which the sequentially extracted syntax elements indicating, for associated positions within the transform coefficient block, as to whether at the respective position a significant or insignificant transform coefficient is situated, are sequentially associated to the positions of the transform coefficient block, among the positions of the transform coefficient block depends on the positions of the significant transform coefficients indicated by previously associated syntax elements. Alternatively, the first-type elements may be context-adaptively entropy decoded using contexts which are individually selected for each of the syntax elements dependent on a number of significant transform coefficients in a neighborhood of the respective syntax element, indicated as being significant by any of the preceding syntax elements..
Ge Video Compression, Llc


 Future order throttling patent thumbnailFuture order throttling
Methods, systems, and apparatus, including computer programs encoded on a computer storage medium, for managing orders. The methods include actions of tracking performance of a fulfillment center in fulfilling orders for items at the fulfillment center, storing historical preparation information that describes historical performance of the fulfillment center, and receiving an order for an item to be fulfilled by the fulfillment center for a fulfillment time.
Accenture Global Services Limited


 Hybrid fitting for a visual prosthesis patent thumbnailHybrid fitting for a visual prosthesis
The present invention is an improved fitting and training system for a visual prosthesis. Fitting a visual prosthesis through automated means is challenging and fitting a visual prosthesis manually is tedious for clinician and patent, and provides great opportunity for error.
Second Sight Medical Products, Inc.


 Method for preventing or treating functional gastrointestinal disorder by lactic acid bacterium patent thumbnailMethod for preventing or treating functional gastrointestinal disorder by lactic acid bacterium
The present invention provides a method for preventing or treating a functional gastrointestinal disorder in a subject in need thereof that includes a step of administering a composition, wherein the composition includes an effective amount of lactobacillus plantarum subsp. Plantarum ps128 and a carrier.
National Yang-ming University


System and placing an order using a local device

A system for purchasing one or more products is provided. The system includes a local device for retrieving identification information and a remote server connected with the local device, an order management system connected with the remote server, and an order fulfillment system connected with the order management system to fulfill the order by obtaining and delivering the product to the user.
Wal-mart Stores, Inc.

Methods for profiliing and quantitating cell-free rna

The invention generally relates to methods for assessing a neurological disorder by characterizing circulating nucleic acids in a blood sample. According to certain embodiments, methods for assessing a neurological disorder include obtaining rna present in a blood sample of a patient suspected of having a neurological disorder, determining a level of rna present in the sample that is specific to brain tissue, comparing the sample level of rna to a reference level of rna specific to brain tissue, determining whether a difference exists between the sample level and the reference level, and indicating a neurological disorder if a difference is determined..
The Board Of Trustees Of The Leland Stanford Junior University

Cache flushing utilizing linked lists

Methods and structure for utilizing linked lists to flush a cache. One exemplary embodiment includes a memory, an interface, and an input/output (i/o) processor.
Avago Technologies General Ip (singapore) Pte. Ltd.

Metrology methods, metrology apparatus and device manufacturing method

A lithographic manufacturing system produces periodic structures with feature sizes less than 10 nm and a direction of periodicity (d). A beam of radiation (1904) having a range of wavelengths in the euv spectrum (1-100 nm or 1-150 nm) is focused into a spot (s) of around 5 μm diameter.
Rwth Aachen University

Method for detection treatment and prevention of neurological development disorders

A method for detection, treatment, and prevention of neurological development disorders utilizes an infrared imaging device, meridian theory of traditional chinese medicine, and predetermined amounts of solid water particles to detect, treat, and prevent a neurological developmental disorder, such as autism. The method detects the disorder by initially identifying at least one hot spot on a patient with an infrared imaging device.

Optimization of electronic display areas

Techniques for optimizing the display area of an electronic display of an article include maximizing the contiguous area of the display, on one or more surfaces of the article, on which text or images may be presented to a user, and/or to minimize the area of a border of the display that is viewable to the user. Optimization techniques may include bending portions of the display, and/or minimizing the footprint of the display border by particularly configuring the electrical connections to the display elements.
Polyera Corporation

Kvits

Kvits is a payment platform that brings the convenience to the consumer and significantly increases the amount of sales to businesses such as restaurants, bars and other food related places. Kvits stimulates the flow of visitors to a great extent by reduction of wait time or so called the three waits cycle (3w's), which includes: the wait to request a check, the wait for a check and the wait for a change or a credit card return.

Marker for prenatal diagnosis and monitoring

The present invention relates to new methods for diagnosing a pregnancy-associated disorder by analyzing fetal dna present in the mother's blood. More specifically, this invention relies on the discovery that the maspin gene is differentially methylated in fetal dna and in maternal dna and provides these new diagnostic methods, which distinguish fetal dna from maternal dna and detect prenatal disorders based on abnormalities in fetal dna level and methylation status..
The Chinese University Of Hong Kong

Methods and systems for treatment of spinal disorders using trans-spinal direct current stimulation

Methods, systems and devices are disclosed for treating a spinal disorder by applying a source of direct current to a spinal cord in animals, including humans. Trans-spinal direct current stimulation (tsdcs) uses direct current via cathodal and/or anodal stimulation to induce cell proliferation, cell differentiation, and/or cell migration at or near the area of the spinal cord being treated, and up-regulates or down-regulates protein expression by cells at or near the area of the spinal cord being treated..

System and managing e-commerce

Disclosed herein includes a system and method for providing an online shopping platform. A memory may store a user's loyalty points for redemption.
Freecause, Inc.

Rny-derived small rnas as biomarkers for atherosclerosis-related disorders

The present invention concerns an in vitro method of diagnosis or prognosis of an atherosclerosis-related disorder by detecting a small y rna (s-rny), as well as the use of an inhibitor of s-rny as a medicament against atherosclerosis-related disorders. The invention also concerns a method for screening for a compound suitable for the treatment of an atherosclerosis-related disorder..
Universite De Nice Sophia Antipolis

Agonists of guanylate cyclase useful for downregulation of pro-inflammatory cytokines

This invention provides a method to prevent, control, and/or treat an inflammatory disease or disorder by administering at least one agonist of guanalyte cyclase receptor, or pharmaceutical compositions thereof, either alone or either concurrently or sequentially with another compound or an active agent used to treat the disease or disorder, and/or with an inhibitor of cgmp-dependent phosphodieasterases.. .
Synergy Pharmaceuticals, Inc.

Generating pressure fluctuations in a line

For generating pressure fluctuations (Δρ) in a fluid (8), the fluid is fed at a constant rate into the inlet (4) of the line (2), the line (2) is flowed through by the fluid (8) and the volume flow of the fluid (8) is throttled to varying degrees at the outlet (6) dynamically over time, in particular periodically, in order by the varying of the throttling to produce pressure fluctuations (Δρ) in the fluid (8) upstream in the line (2) dynamically over time. On a pressure modulator (24), an outlet opening (26) can be connected to a line (2), wherein the outlet opening (26) opens out into a clearance (28), and so during operation the fluid (8) leaves the outlet opening (26) as a fluid jet (30) along a fluid path (32) and enters the clearance (28).
Eucatech Ag

Compositions and methods for detecting predisposition to a substance use disorder

The present invention provides screening kits, compositions, and diagnostic methods for determining whether a subject has a predisposition to, or likelihood of having, a substance use disorder by determining a nucleic acid methylation profile from a biological sample from the subject, wherein a given profile indicates that the subject has a predisposition to a substance use disorder.. .

Cdk4/6 inhibitor dosage formulations for the protection of hematopoietic stem and progenitor cells during chemotherapy

This invention is in the area of dosage formulations and methods of administering a cdk4/6 inhibitor for the transient protection of healthy cells, and in particular hematopoietic stem and progenitor cells (hspc), from damage associated with dna damaging chemotherapeutic agents in subjects undergoing dna damaging chemotherapeutic therapies for the treatment of proliferative disorders. In one aspect, improved protection of healthy cells is disclosed using a dosage that provides desirable pharmacokinetic and pharmacodynamic characteristics, including auc, tmax, cmax, dosage-corrected auc, and dosage-corrected cmax.
G1 Therapeutics, Inc.

Methods for diagnosing and treating immune disease

Provided are methods and assays relating to the treatment of an immune disease or disorder by administering an inhibitor that binds slamf7. Also provided are methods and assays related to the diagnosis of an immune disease or disorder by measuring expression level of slamf7 in a biological sample obtained from a subject..
The General Hospital Corporation

Lightweight foam safety shoes

The present invention provides safety shoes with a built-in toe cap, wherein a foam shoe in which the outsole and the upper are integrated by foaming a synthetic resin is formed, and a toe cap is inserted into a toe cap groove before the foam shoe is cooled by forming the toe cap groove at the outsole and the upper at the front inner part of the foam shoe. In the toe cap, a support border, comprising a metal material, making contact with the bottom, is formed at the lower end of a cover portion making contact with the upper, and a reinforcing piece crossing the bottom is formed at the support border by welding; or a ground plate, comprising an engineering plastic, which is in contact with the bottom, is formed at the lower end of a cover portion making contact with the upper..
Fine Chemical Co., Ltd.

Compositions and methods for treating alzheimer`s disease and related disorders and promoting a healthy nervous system

The present invention relates generally to methods of inhibiting the onset and progression of alzheimer's disease (ad), mild cognitive impairment (mci), and related neurodegenerative disorders involving amyloidosis. The methods involve administering a composition comprising a therapeutically effective amount of d-pinitol to individuals who are at risk of developing the disease or have one or more symptoms of the disease.
Icahn School Of Medicine At Mount Sinai

System and managing vendors, tax allocation and posting journal entries

The present invention consists of an improved system and method for tracking expenses and billing them to a client, matter, task, activity, client group or phase and assessing goods and services purchased to these categories on a line by line basis. The system also allows an employee to place an order by selecting from a list of preapproved vendors and checking both vendor ratings and item ratings prior to purchase.

Automatic detection of queries missing order-by via unit test

In one aspect, there is provided a method. The method may intercepting a result provided by a database in response to a query; modifying the intercepted result to enable detection of an order by problem; and detecting, based on the modified intercepted result, whether the query is missing an order by clause.

System and methods for processor-based memory scheduling

The invention relates to a system and methods for memory scheduling performed by a processor using a characterization logic and a memory scheduler. The processor influences the order by which memory requests are serviced and provides associated hints to the memory scheduler, where scheduling actually takes place..
Cornell University

Modulation of nlgn4 expression, nk cell activity in non-alcoholic fatty liver disease (nafld)

The present invention provides a method of treating, attenuating or preventing a liver disorder by inhibiting ngn4 expression and thereby modulating the activity of nk cells. The present invention further relates to diagnosing a liver disorder by evaluating nlgn4 expression in nk cells..
Hadasit Medical Research Services And Development Ltd.

Composition containing herbal medicine extracts of pinellia and scutellaria for reducing side effects due to anticancer drugs

The present invention relates to a composition containing a pinelliae rhizoma and scutellariae radix extract as an active ingredient to reduce side effects caused by an anticancer drug, and more particularly, a composition for reducing side effects such as damage to the gastrointestinal tract and a gastrointestinal motility disorder by administering an anticancer drug. The composition of the present invention has an excellent effect of reducing side effects in administration of the anticancer drug through an antioxidative function, and synthesis, secretion and control of the functions of gastrin and serotonin producing gastrointestinal endocrine cells..
Comprehensive And Integrative Medicine Institute

Window treatment rod bracket

A window treatment hanging apparatus operable to releasably secure a window treatment rod bracket to a wall. The window treatment hanging apparatus further includes a body that is planar in manner and rectangular in shape.

Concession preordering for pickup or delivery during an event

There is provided systems and method for concession preordering for pickup or delivery during an event. A user may attend an event at a venue and have purchased admission for the event.

Structured information differentiation in naming

Structured information differentiation in naming techniques are described. In one or more embodiments, first and second collections of structured information are tokenized to generate a first ordered list of tokens that correspond to the first collection of structured information and a second ordered list of tokens that correspond to the second collection of structured information.

Methods of diagnosis and treatment

A method for diagnosing a cardiac ischemic event and a kit for detecting biomarkers used in the method. Also provided is a method for treating a ppar-related disorder by administering a pharmaceutical composition containing one or more long chain fatty acids..
Theranostics Lab

Method for improved management of a purchase order by internet

A method for improved management of a purchase order comprises searching online for at least one product or group of products similar to each other to be ordered from a generic supplier and obtaining a confirmation of availability. The step of searching for the product to be ordered from the generic supplier can be extended to search for the product or the group of products or alternative products available at at least one alternative supplier.
Ingram Micro S.r.l. (societa A Socio Unico)

Humanin, analogs and cancer treatment methods and uses thereof

Described herein are methods of enhancing chemotherapeutic treatment of a hyperproliferative disorder by, in part, administering a composition comprising one or more humanin polypeptides to a subject receiving chemotherapy.. .
Los Angeles Biomedical Research Institute At Harbor-ucla Medical Center

Coding of significance maps and transform coefficient blocks

A higher coding efficiency for coding a significance map indicating positions of significant transform coefficients within a transform coefficient block is achieved by the scan order by which the sequentially extracted syntax elements indicating, for associated positions within the transform coefficient block, as to whether at the respective position a significant or insignificant transform coefficient is situated, are sequentially associated to the positions of the transform coefficient block, among the positions of the transform coefficient block depends on the positions of the significant transform coefficients indicated by previously associated syntax elements. Alternatively, the first-type elements may be context-adaptively entropy decoded using contexts which are individually selected for each of the syntax elements dependent on a number of significant transform coefficients in a neighborhood of the respective syntax element, indicated as being significant by any of the preceding syntax elements..
Ge Video Compression Llc

Amyloid precursor protein mrna blockers for treating down sydnrome and alzheimer's disease

The present disclosure relates to methods for treating a neurodegenerative disorder by administering an effective amount of an agent that inhibits or reduces translation of amyloid precursor protein. In some embodiments, the neurodegenerative disorder is alzheimer's disease or down syndrome.
The Broad Institute, Inc.

Electronic shopping mall system, terminal, display control method, recording medium, and program

A display (1203) displays product information acquired from a server in a scrollable manner. An estimator (1204) estimates whether or not a user has read warning information included in the product information.
Rakuten, Inc.

Modifying electronic orders during a fulfillment process

Systems, methods, and other embodiments associated with modifying electronic orders during fulfillment are described. In one embodiment, a computing system includes order logic configured to receive a cancellation request to modify an electronic order that is for one or more items sold through an electronic commerce source.
Oracle International Corporation

Information processing device, controlling information processing device, program, and information storage medium

Authentication data indicates a plurality of types of operation which a user should perform in a predetermined order via a touch panel and a number of fingers, as to each one of the plurality of types of operation, with which the user should touch the touch panel when performing an operation corresponding to the one of the plurality of types of operation. An authentication processing execution unit executes authentication processing by determining, based on a result of detection by the touch panel, whether or not an operation corresponding to each of the plurality of types of operation has been performed in the predetermined order by touching the touch panel with a number of fingers set for each of the plurality of types of operation..
Rakuten, Inc.

Zero gas refiner for co2 concentration measurement device and co2 concentration measurement system

This invention provides a zero gas refiner for co2 concentration measurement device that can continuously refine a zero gas that is preferable for co2 concentration measurement. This invention adopts the zero gas refiner comprising a water adsorbent and a co2 adsorbent that desorb an adsorbed component and restore an adsorption ability by being heated to a predetermined restoration temperature, a refiner body that adsorbs water and co2 in an introduced sample gas or air in this order by the use of the water adsorbent and the co2 adsorbent housed inside of the refiner body so as to refine a zero gas and that leads out the zero gas, and a heating mechanism that applies heat to the refiner body at a time when the adsorption ability of the water adsorbent or the co2 adsorbent drops to an amount that is less than or equal to a predetermined amount..
Horiba, Ltd.

Customer facing display with customer interaction for order specification

An on-premises computing system of a public accommodation detects presence of a customer by obtaining an identifier wirelessly transmitted by a wireless device carried by that customer. The identifier is received from the wireless device via a wireless local area network access point of the on-premises computing system.

Lateral flow immunoassay for complement activation and methods of use for point-of-care assessment of complement-associated disorders

A method for treating an individual at risk for a complement-associated disorder is provided, the method including: (a) obtaining a sample of a body fluid from the individual; (b) measuring a complement activation level in the sample via a point-of-care lateral flow immunoassay; (c) correlating the complement activation level in the sample to a risk of a complement-associated disorder by comparing the complement activation level in the sample to a reference level in a control, wherein a deviation in complement activation level in the sample compared to the reference level in the control indicates the individual is at risk for a complement-associated disorder; (d) selecting a treatment for the individual, based on the correlating of step (c); and (e) treating the individual with the treatment selected in accordance with step (d). Lateral flow immunoassays for the qualitative and quantitative point-of-care detection of complement activation and a method of monitoring an individual suffering from a complement-associated disorder are also provided herein..
Kypha, Inc.

Method for making 32-bit addressing of sv data by utilizing fpga

This invention relates to a method for making 32-bit addressing of sv data by utilizing fpga, which may be applied to processing digital sampling data in an equipment of an intelligent substation. Specifically, the method includes the following steps: fpga receiving naked sv data packages generated based on ieee802.3 standard; analyzing data structure of ethernet frame; based on characteristics of the ethernet frame of the sv data, the sv data of the network byte sequence being reorganized by utilizing asn.1 coding rules, so that the sv data being converted into a data that can be directly accessed by 32-bit addressing processors.
Beijing Sifang Automation Co., Ltd

Self learning method and system to provide an alternate or ancillary product choice in response to a product selection

A system including: a memory element for storing an artificial intelligence program (aip); an interface element for receiving, from a wireless communications device (wcd), a first portion of an order; and a processor for generating, using the aip, an offer in response to items or services in the first portion of the order. The interface element is for transmitting the offer to the wcd and receiving, from the wcd, a second portion of the order.
Retaildna Llc

Methods to treat alzheimer's disease using apoe inhibitors

Non-familial late-onset alzheimer's disease (load), a condition associated with the accumulation of the amyloid precursor protein-derived (app) abeta fragment in the brain, can be the consequence of combined genetic and environmental risk factors. One of these risk factors is the presence of the apolipoprotein e4 (apoe4) allele.
The Trustees Of Columbia University In The City Of New York

Compositions and methods for using huperzine and analogs thereof

A method of treating a seizure disorder is described wherein an acetylcholinesterase(ache) inhibitor is administered to a subject having a seizure disorder and an increased risk of a cardiac event from the seizure disorder, wherein the ache inhibitor decreases the risk of such cardiac event. Further described are methods of decreasing the risk of a cardiac event in subjects with or without a seizure disorder by administering a therapeutically effective amount of an ache inhibitor.
Insero Health Inc.



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  • Parathyroid Hormone
  • Mood Disorder
  • Resorption
  • Thyroid Hormone
  • Phosphonate
  • Bisphosphonate
  • Binding Agent
  • Osteoclast
  • Bone Density
  • Bone Resorption
  • Bone Mineral Density
  • Contraindicate
  • Hypercalcemia
  • Hypocalcemia
  • Major Depression


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