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 Methods and systems for treatment of spinal disorders using trans-spinal direct current stimulation patent thumbnailnew patent Methods and systems for treatment of spinal disorders using trans-spinal direct current stimulation
Methods, systems and devices are disclosed for treating a spinal disorder by applying a source of direct current to a spinal cord in animals, including humans. Trans-spinal direct current stimulation (tsdcs) uses direct current via cathodal and/or anodal stimulation to induce cell proliferation, cell differentiation, and/or cell migration at or near the area of the spinal cord being treated, and up-regulates or down-regulates protein expression by cells at or near the area of the spinal cord being treated..

 System and  managing e-commerce patent thumbnailSystem and managing e-commerce
Disclosed herein includes a system and method for providing an online shopping platform. A memory may store a user's loyalty points for redemption.
Freecause, Inc.


 Rny-derived small rnas as biomarkers for atherosclerosis-related disorders patent thumbnailRny-derived small rnas as biomarkers for atherosclerosis-related disorders
The present invention concerns an in vitro method of diagnosis or prognosis of an atherosclerosis-related disorder by detecting a small y rna (s-rny), as well as the use of an inhibitor of s-rny as a medicament against atherosclerosis-related disorders. The invention also concerns a method for screening for a compound suitable for the treatment of an atherosclerosis-related disorder..
Universite De Nice Sophia Antipolis


 Agonists of guanylate cyclase useful for downregulation of pro-inflammatory cytokines patent thumbnailAgonists of guanylate cyclase useful for downregulation of pro-inflammatory cytokines
This invention provides a method to prevent, control, and/or treat an inflammatory disease or disorder by administering at least one agonist of guanalyte cyclase receptor, or pharmaceutical compositions thereof, either alone or either concurrently or sequentially with another compound or an active agent used to treat the disease or disorder, and/or with an inhibitor of cgmp-dependent phosphodieasterases.. .
Synergy Pharmaceuticals, Inc.


 Generating pressure fluctuations in a line patent thumbnailGenerating pressure fluctuations in a line
For generating pressure fluctuations (Δρ) in a fluid (8), the fluid is fed at a constant rate into the inlet (4) of the line (2), the line (2) is flowed through by the fluid (8) and the volume flow of the fluid (8) is throttled to varying degrees at the outlet (6) dynamically over time, in particular periodically, in order by the varying of the throttling to produce pressure fluctuations (Δρ) in the fluid (8) upstream in the line (2) dynamically over time. On a pressure modulator (24), an outlet opening (26) can be connected to a line (2), wherein the outlet opening (26) opens out into a clearance (28), and so during operation the fluid (8) leaves the outlet opening (26) as a fluid jet (30) along a fluid path (32) and enters the clearance (28).
Eucatech Ag


 Compositions and methods for detecting predisposition to a substance use disorder patent thumbnailCompositions and methods for detecting predisposition to a substance use disorder
The present invention provides screening kits, compositions, and diagnostic methods for determining whether a subject has a predisposition to, or likelihood of having, a substance use disorder by determining a nucleic acid methylation profile from a biological sample from the subject, wherein a given profile indicates that the subject has a predisposition to a substance use disorder.. .

 Cdk4/6 inhibitor dosage formulations for the protection of hematopoietic stem and progenitor cells during chemotherapy patent thumbnailCdk4/6 inhibitor dosage formulations for the protection of hematopoietic stem and progenitor cells during chemotherapy
This invention is in the area of dosage formulations and methods of administering a cdk4/6 inhibitor for the transient protection of healthy cells, and in particular hematopoietic stem and progenitor cells (hspc), from damage associated with dna damaging chemotherapeutic agents in subjects undergoing dna damaging chemotherapeutic therapies for the treatment of proliferative disorders. In one aspect, improved protection of healthy cells is disclosed using a dosage that provides desirable pharmacokinetic and pharmacodynamic characteristics, including auc, tmax, cmax, dosage-corrected auc, and dosage-corrected cmax.
G1 Therapeutics, Inc.


 Methods for diagnosing and treating immune disease patent thumbnailMethods for diagnosing and treating immune disease
Provided are methods and assays relating to the treatment of an immune disease or disorder by administering an inhibitor that binds slamf7. Also provided are methods and assays related to the diagnosis of an immune disease or disorder by measuring expression level of slamf7 in a biological sample obtained from a subject..
The General Hospital Corporation


 Lightweight foam safety shoes patent thumbnailLightweight foam safety shoes
The present invention provides safety shoes with a built-in toe cap, wherein a foam shoe in which the outsole and the upper are integrated by foaming a synthetic resin is formed, and a toe cap is inserted into a toe cap groove before the foam shoe is cooled by forming the toe cap groove at the outsole and the upper at the front inner part of the foam shoe. In the toe cap, a support border, comprising a metal material, making contact with the bottom, is formed at the lower end of a cover portion making contact with the upper, and a reinforcing piece crossing the bottom is formed at the support border by welding; or a ground plate, comprising an engineering plastic, which is in contact with the bottom, is formed at the lower end of a cover portion making contact with the upper..
Fine Chemical Co., Ltd.


 Compositions and methods for treating alzheimer`s disease and related disorders and promoting a healthy nervous system patent thumbnailCompositions and methods for treating alzheimer`s disease and related disorders and promoting a healthy nervous system
The present invention relates generally to methods of inhibiting the onset and progression of alzheimer's disease (ad), mild cognitive impairment (mci), and related neurodegenerative disorders involving amyloidosis. The methods involve administering a composition comprising a therapeutically effective amount of d-pinitol to individuals who are at risk of developing the disease or have one or more symptoms of the disease.
Icahn School Of Medicine At Mount Sinai


System and managing vendors, tax allocation and posting journal entries


The present invention consists of an improved system and method for tracking expenses and billing them to a client, matter, task, activity, client group or phase and assessing goods and services purchased to these categories on a line by line basis. The system also allows an employee to place an order by selecting from a list of preapproved vendors and checking both vendor ratings and item ratings prior to purchase.

Automatic detection of queries missing order-by via unit test


In one aspect, there is provided a method. The method may intercepting a result provided by a database in response to a query; modifying the intercepted result to enable detection of an order by problem; and detecting, based on the modified intercepted result, whether the query is missing an order by clause.

System and methods for processor-based memory scheduling


The invention relates to a system and methods for memory scheduling performed by a processor using a characterization logic and a memory scheduler. The processor influences the order by which memory requests are serviced and provides associated hints to the memory scheduler, where scheduling actually takes place..
Cornell University


Modulation of nlgn4 expression, nk cell activity in non-alcoholic fatty liver disease (nafld)


The present invention provides a method of treating, attenuating or preventing a liver disorder by inhibiting ngn4 expression and thereby modulating the activity of nk cells. The present invention further relates to diagnosing a liver disorder by evaluating nlgn4 expression in nk cells..
Hadasit Medical Research Services And Development Ltd.


Composition containing herbal medicine extracts of pinellia and scutellaria for reducing side effects due to anticancer drugs


The present invention relates to a composition containing a pinelliae rhizoma and scutellariae radix extract as an active ingredient to reduce side effects caused by an anticancer drug, and more particularly, a composition for reducing side effects such as damage to the gastrointestinal tract and a gastrointestinal motility disorder by administering an anticancer drug. The composition of the present invention has an excellent effect of reducing side effects in administration of the anticancer drug through an antioxidative function, and synthesis, secretion and control of the functions of gastrin and serotonin producing gastrointestinal endocrine cells..
Comprehensive And Integrative Medicine Institute


Window treatment rod bracket


A window treatment hanging apparatus operable to releasably secure a window treatment rod bracket to a wall. The window treatment hanging apparatus further includes a body that is planar in manner and rectangular in shape.

Concession preordering for pickup or delivery during an event


There is provided systems and method for concession preordering for pickup or delivery during an event. A user may attend an event at a venue and have purchased admission for the event.

Structured information differentiation in naming


Structured information differentiation in naming techniques are described. In one or more embodiments, first and second collections of structured information are tokenized to generate a first ordered list of tokens that correspond to the first collection of structured information and a second ordered list of tokens that correspond to the second collection of structured information.

Methods of diagnosis and treatment


A method for diagnosing a cardiac ischemic event and a kit for detecting biomarkers used in the method. Also provided is a method for treating a ppar-related disorder by administering a pharmaceutical composition containing one or more long chain fatty acids..
Theranostics Lab


Method for improved management of a purchase order by internet


A method for improved management of a purchase order comprises searching online for at least one product or group of products similar to each other to be ordered from a generic supplier and obtaining a confirmation of availability. The step of searching for the product to be ordered from the generic supplier can be extended to search for the product or the group of products or alternative products available at at least one alternative supplier.
Ingram Micro S.r.l. (societa A Socio Unico)


Humanin, analogs and cancer treatment methods and uses thereof


Described herein are methods of enhancing chemotherapeutic treatment of a hyperproliferative disorder by, in part, administering a composition comprising one or more humanin polypeptides to a subject receiving chemotherapy.. .
Los Angeles Biomedical Research Institute At Harbor-ucla Medical Center


Coding of significance maps and transform coefficient blocks


A higher coding efficiency for coding a significance map indicating positions of significant transform coefficients within a transform coefficient block is achieved by the scan order by which the sequentially extracted syntax elements indicating, for associated positions within the transform coefficient block, as to whether at the respective position a significant or insignificant transform coefficient is situated, are sequentially associated to the positions of the transform coefficient block, among the positions of the transform coefficient block depends on the positions of the significant transform coefficients indicated by previously associated syntax elements. Alternatively, the first-type elements may be context-adaptively entropy decoded using contexts which are individually selected for each of the syntax elements dependent on a number of significant transform coefficients in a neighborhood of the respective syntax element, indicated as being significant by any of the preceding syntax elements..
Ge Video Compression Llc


Amyloid precursor protein mrna blockers for treating down sydnrome and alzheimer's disease


The present disclosure relates to methods for treating a neurodegenerative disorder by administering an effective amount of an agent that inhibits or reduces translation of amyloid precursor protein. In some embodiments, the neurodegenerative disorder is alzheimer's disease or down syndrome.
The Broad Institute, Inc.


Electronic shopping mall system, terminal, display control method, recording medium, and program


A display (1203) displays product information acquired from a server in a scrollable manner. An estimator (1204) estimates whether or not a user has read warning information included in the product information.
Rakuten, Inc.


Modifying electronic orders during a fulfillment process


Systems, methods, and other embodiments associated with modifying electronic orders during fulfillment are described. In one embodiment, a computing system includes order logic configured to receive a cancellation request to modify an electronic order that is for one or more items sold through an electronic commerce source.
Oracle International Corporation


Information processing device, controlling information processing device, program, and information storage medium


Authentication data indicates a plurality of types of operation which a user should perform in a predetermined order via a touch panel and a number of fingers, as to each one of the plurality of types of operation, with which the user should touch the touch panel when performing an operation corresponding to the one of the plurality of types of operation. An authentication processing execution unit executes authentication processing by determining, based on a result of detection by the touch panel, whether or not an operation corresponding to each of the plurality of types of operation has been performed in the predetermined order by touching the touch panel with a number of fingers set for each of the plurality of types of operation..
Rakuten, Inc.


Zero gas refiner for co2 concentration measurement device and co2 concentration measurement system


This invention provides a zero gas refiner for co2 concentration measurement device that can continuously refine a zero gas that is preferable for co2 concentration measurement. This invention adopts the zero gas refiner comprising a water adsorbent and a co2 adsorbent that desorb an adsorbed component and restore an adsorption ability by being heated to a predetermined restoration temperature, a refiner body that adsorbs water and co2 in an introduced sample gas or air in this order by the use of the water adsorbent and the co2 adsorbent housed inside of the refiner body so as to refine a zero gas and that leads out the zero gas, and a heating mechanism that applies heat to the refiner body at a time when the adsorption ability of the water adsorbent or the co2 adsorbent drops to an amount that is less than or equal to a predetermined amount..
Horiba, Ltd.


Customer facing display with customer interaction for order specification


An on-premises computing system of a public accommodation detects presence of a customer by obtaining an identifier wirelessly transmitted by a wireless device carried by that customer. The identifier is received from the wireless device via a wireless local area network access point of the on-premises computing system.

Lateral flow immunoassay for complement activation and methods of use for point-of-care assessment of complement-associated disorders


A method for treating an individual at risk for a complement-associated disorder is provided, the method including: (a) obtaining a sample of a body fluid from the individual; (b) measuring a complement activation level in the sample via a point-of-care lateral flow immunoassay; (c) correlating the complement activation level in the sample to a risk of a complement-associated disorder by comparing the complement activation level in the sample to a reference level in a control, wherein a deviation in complement activation level in the sample compared to the reference level in the control indicates the individual is at risk for a complement-associated disorder; (d) selecting a treatment for the individual, based on the correlating of step (c); and (e) treating the individual with the treatment selected in accordance with step (d). Lateral flow immunoassays for the qualitative and quantitative point-of-care detection of complement activation and a method of monitoring an individual suffering from a complement-associated disorder are also provided herein..
Kypha, Inc.


Method for making 32-bit addressing of sv data by utilizing fpga


This invention relates to a method for making 32-bit addressing of sv data by utilizing fpga, which may be applied to processing digital sampling data in an equipment of an intelligent substation. Specifically, the method includes the following steps: fpga receiving naked sv data packages generated based on ieee802.3 standard; analyzing data structure of ethernet frame; based on characteristics of the ethernet frame of the sv data, the sv data of the network byte sequence being reorganized by utilizing asn.1 coding rules, so that the sv data being converted into a data that can be directly accessed by 32-bit addressing processors.
Beijing Sifang Automation Co., Ltd


Self learning method and system to provide an alternate or ancillary product choice in response to a product selection


A system including: a memory element for storing an artificial intelligence program (aip); an interface element for receiving, from a wireless communications device (wcd), a first portion of an order; and a processor for generating, using the aip, an offer in response to items or services in the first portion of the order. The interface element is for transmitting the offer to the wcd and receiving, from the wcd, a second portion of the order.
Retaildna Llc


Methods to treat alzheimer's disease using apoe inhibitors


Non-familial late-onset alzheimer's disease (load), a condition associated with the accumulation of the amyloid precursor protein-derived (app) abeta fragment in the brain, can be the consequence of combined genetic and environmental risk factors. One of these risk factors is the presence of the apolipoprotein e4 (apoe4) allele.
The Trustees Of Columbia University In The City Of New York


Compositions and methods for using huperzine and analogs thereof


A method of treating a seizure disorder is described wherein an acetylcholinesterase(ache) inhibitor is administered to a subject having a seizure disorder and an increased risk of a cardiac event from the seizure disorder, wherein the ache inhibitor decreases the risk of such cardiac event. Further described are methods of decreasing the risk of a cardiac event in subjects with or without a seizure disorder by administering a therapeutically effective amount of an ache inhibitor.
Insero Health Inc.


Method for reprogramming somatic cells to pancreatic beta cells


The present invention relates to a method for reprogramming a somatic cell (e.g. A pancreatic ductal cell, a skin fibroblast or a keratinocyte) to a pancreatic β-cell.
Cancer Research Technology Limited


Method of treating central nervous system disorders with borrelia burgdorferi antigen


The present invention relates to a treatment for mammalian subjects suffering from a central nervous system (cns) disorder by administering a composition comprising an borrelia burgdorferi antigen at a sub-vaccine level effective to alleviate symptoms of the cns disorder.. .
Beech Tree Labs, Inc.


Flexible ship schedules and dynamic discounts


Electronic buying and selling systems and methods are provided. In particular, relations among distinct price curves and buyers or potential buyers are disclosed.
Ewinwin, Inc.


Autonomic reclamation processing on sequential storage media


Various embodiments for autonomic reclamation of data stored on at least one sequential storage media are provided. In one exemplary embodiment, active data is identified, read out, and stored in a sequential order by starting at a beginning block address of the at least one sequential storage media.
International Business Machines Corporation


Systems and methods for transcriptome analysis


The invention generally provides systems and methods for analysis of rna-seq reads in which an annotated reference is represented as a directed acyclic graph (dag) or similar data structure. Features such as exons and introns from the reference provide nodes in the dag and those features are linked as pairs in their canonical genomic order by edges.
Seven Bridges Genomics Inc.


Method and system for network function placement


A method implemented for network function placement is disclosed. The method optimizes network function placement for each traffic flow, to minimize the overall inter-pod traffic volume.

Hybrid fitting for a visual prosthesis


The present invention is an improved fitting and training system for a visual prosthesis. Fitting a visual prosthesis through automated means is challenging and fitting a visual prosthesis manually is tedious for clinician and patent, and provides great opportunity for error.

Methods and use with a trimmer to produce a plurality of books having different trim sizes


Methods and apparatus for use with a trimmer to produce a plurality of books having different trim sizes are disclosed. An example method includes obtaining recipient data; based on the recipient data, generating an order to produce first books and second books, the first books having a first size and the second books having a second size, the second size different from the first size; and producing the first books and the second books in accordance with the order by: actuating a first backstop to enable a first book of the first books to engage the first backstop; trimming the first book with a cutting device; and actuating a second backstop to enable a second book of the second books to engage the second backstop; and trimming the second book with the cutting device, the first backstop at a first distance from the cutting device and the second backstop at a second distance from the cutting device..

Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases


This invention also provides a method to prevent, control, and treat a lipid metabolism disorder, a billary disorder, cardiovascular disease, obesity or an endocrine disorder by administering at least one agonist of guanalyte cyclase receptor either alone or in combination with a compound typically used to treat the disorder and or with an an inhibitor of cgmp-dependent phosphodieasterases.. .

Film-forming apparatus


In a film-forming apparatus according to an aspect, a substrate placed on a substrate placing region passes through a first region and a second region in this order by rotation of a placing table. A precursor gas is supplied to the first region.
Tokyo Electron Limited


Method for inhibiting bone resorption


The invention is directed to a method of inhibiting bone resorption. The method comprises administering to a human an amount of sclerostin inhibitor that reduces a bone resorption marker level for at least 2 weeks.
Amgen Inc.


System and internet access to a personal television service


A communication system and a family of methods for remote access to personal television service are disclosed. A remote personal tv service center provides centralized program guide information.
Tivo Inc.


Increased visibility during order management in a network-based supply chain environment


A system, method and article of manufacture are provided for a first business entity to provide a network-based supply chain framework for collaborative order management between at least a second and a third independent business entity, such as a service provider, vendor, reseller, manufacturer and the like. A request for an order is received over a network with an automated system, from at least a second business entity.
Accenture Global Services Limited


Sorting database collections for parallel processing


Techniques are described for assigning collections of records to parallel processing tasks for sorting index keys of the records. In one example, a method includes determining an order of the collections of records in a descending order by byte length of an index key of each of the collections of records.
International Business Machines Corporation


Treatment of autophagy-based disorders and related pharmaceutical compositions, diagnostic and screening assays and kits


In one embodiment, the invention provides a method of treating a subject suffering from a mycobacterium infection by administering to the subject a therapeutically-effective amount of a degradative autophagy agonist or a secretory autophagy antagonist. In another embodiment, the invention provides a method of treating a subject suffering from one or more diseases selected from the group consisting of a mycobacterium infection, an inflammatory disorder, an immune disorder, a cancer and a neurodegenerative disorder by administering to the subject a therapeutically-effective amount of a tbk-1 antagonist (e.g.
Stc.unm


Gp2 isoforms and their use in autoantibody capture


The invention relates to a method for binding or capturing autoantibodies directed to various glycoprotein 2 (gp2) isoforms. In particular the invention provides an in vitro method for the diagnosis of an autoimmune disorder by the detection of autoantibodies that bind one or more isoforms of gp2.
Ga Generic Assays Gmbh


Ac-direct drive-type led driving device


The present invention relates to a device for driving leds and, more specifically, to an ac-direct drive-type led driving device, capable of sequentially driving leds connected in series in reverse order by starting with an led located at the end until a certain size of power is supplied, and sequentially driving the leds connected in series in order if the certain size of power is supplied, rather than measuring the size of a rectified power and sequentially driving the leds connected in series based on the measured size of the power; thereby equalizing the power consumption of all the leds connected in series to thereby equalize the life span of the leds regardless of the serial connection order of the leds and unifying the brightness of all the leds connected in series.. .

Rule based closure of purchase orders


One or more computers may close a purchase order by use of rules. Certain embodiments use values of attributes of a line in a purchase order (po) to identify a rule among multiple rules.
Oracle International Corporation


Method and determining identity and programing based on image features


Embodiments of a system and related methods are disclosed for identifying performers in a performance. The system takes one or more photos capturing faces of multiple performers in a performance and generates one photo for each of the faces.
Facialnetwork, Inc.


Method and system for rebrokering orders in a trading system


Systems and methods are described herein for supporting the trading of bonds in a computerized system using broker dealers as intermediaries. Broker dealers receive orders relating to particular transactions and have the option to accept the order by submitting a matching counter order, or to rebroker the order with the same or modified terms to a number of other investors or additional broker dealers.
Wall Corporation


Method, system and computer storage medium for detecting an audio input interface


Provided is a method for detecting an audio input interface, comprising: acquiring input signals of every one of audio input interfaces; acquiring energy values of said input signals of every one of said audio input interfaces, and acquiring an interface identification of the audio input interface of which the energy value is the maximum among the energy values; adding said interface identification acquired herein into an identification sequence in an order by acquiring time; and identifying the audio input interface, of which the interface identification is saved most often in said identification sequence, as a valid audio input interface. Also provided is a system for detecting an audio input interface.
Tencent Technology (shenzhen) Company Limited


Golf ball putting game


A golf ball putting game adapted for competitive indoor use by several players utilizes a portable elongated track positioned on a flat area, together with a conventional golf putter and balls. The track is fabricated of a material which can be easily rolled up for storage and unrolled for play and that has a surface texture suitable for putting golf balls.

Variable length coding method and variable length decoding method


The present invention is a variable length coding method for coding coefficients in each block which are obtained by performing frequency transformation on picture data of a moving picture per block having a predetermined size, and comprises: a coefficient scanning step of scanning the coefficients in the block in a predetermined order; and a coding step of coding the coefficients scanned in the coefficient scanning step into variable length codes in a predetermined order by switching a plurality of tables to be used for coding. Here, a direction of switching between the tables may be one-directional.
Panasonic Intellectual Property Corporation Of America


Analyzing the advertisement bidding-chain


Automatically collecting advertisement bidding order by automatically accessing at least one internet content site and presenting the internet content site with at least one virtual user data and an at least one of ip address representing a geographic location of the virtual user. In response, receiving from the internet content site advertisement content, and bidding data.

System and classifying a skin infection


A system and computer-implemented method for classifying skin disorders using an image of a skin portion is provided. The system comprises a server configured to receive the image of the skin portion from an electronic communication device and process the received image of the skin portion, wherein the processing comprises at least one of: resizing, removing artifacts and noise, applying new color space, sharpening the image and correcting background.
Cognizant Technology Solutions India Pvt. Ltd.


Web-based recorder configuration utility


A method and system for identifying a data recorder based upon a unique signature generated for the data recorder. Configuration information is received, the information specifying a plurality of data recording input parameters which are selected to facilitate use of the data recorder in a particular data recording application.
L-3 Communications Corporation


Combination therapy for the treatment of ocular neovascular disorders


The invention features methods for treating a patient diagnosed with, or at risk of developing, a neovascular disorder by administering a pdgf antagonist and a vegf antagonist to the patient. The invention also features a pharmaceutical composition containing a pdgf antagonist and a vegf antagonist for the treatment or prevention of a neovascular disorder..
Ophthotech Corporation


Combination therapy for the treatment of ocular neovascular disorders


The invention features methods for treating a patient diagnosed with, or at risk of developing, a neovascular disorder by administering a pdgf antagonist and a vegf antagonist to the patient. The invention also features a pharmaceutical composition containing a pdgf antagonist and a vegf antagonist for the treatment or prevention of a neovascular disorder..
Ophthotech Corporation


Price banding visualization


A computer-implemented method facilitates an order by a market participant for a trade of a financial instrument via an exchange computer system. The method includes determining a price band for valid orders of the financial instrument, generating an order entry interface configured for entry of data by the market participant indicative of the order of the financial instrument, the order entry interface including a visual indication of the price band, capturing data indicative of the order entered via the order entry interface, and transmitting the captured data to the exchange computer system..
Chicago Mercantile Exchange Inc.


Method for recommending document


A method for recommending document is revealed. First give respective first document an interest score or arranged the respective first document in order by a first device.
Richplay Information Co., Ltd.


Compositions and methods for treating alzheimer's disease and related disorders and promoting a healthy nervous system


The present invention relates generally to methods of inhibiting the onset and progression of alzheimer's disease (ad), mild cognitive impairment (mci), and related neurodegenerative disorders involving amyloidosis. The methods involve administering a composition comprising a therapeutically effective amount of d-pinitol to individuals who are at risk of developing the disease or have one or more symptoms of the disease.
Icahn School Of Medicine At Mount Sinai


Information processing apparatus, information processing apparatus startup method, and recording medium


An information processing apparatus includes a startup condition acquisition unit that acquires a startup condition of multiple program modules, a determination unit that determines a startup order of the multiple program modules by multiple cpu cores, a startup unit that starts up the multiple program modules by executing an executable program module in accordance with the startup order by the multiple cpu cores, an updating unit that updates load information that indicates multiple cpu core load that fluctuates during a startup process, and a limitation unit that limits startup of the program module by the multiple cpu cores based on the load information updated by the updating unit.. .
Ricoh Company, Ltd.


Multi-instance redo apply


A method, apparatus, and system for multi-instance redo apply is provided for standby databases. A multi-instance primary database generates a plurality of redo records, which are received and applied by a physical standby running a multi-instance standby database.
Oracle International Corporation


Systems and methods for transcriptome analysis


The invention generally provides systems and methods for analysis of rna-seq reads in which an annotated reference is represented as a directed acyclic graph (dag) or similar data structure. Features such as exons and introns from the reference provide nodes in the dag and those features are linked as pairs in their canonical genomic order by edges.
Seven Bridges Genomics Inc.


Device and control method thereof


One embodiment provides a device including a processor, a detector and a controller. The processor acquires a first operation state of a network-connected device, a second operation state of a video recorder and content information regarding a content playable by the video recorder.
Toshiba Lifestyle Products & Services Corporation


Methods of treating a patient having an autoimmune disorder by administering a baff antagonist


Therapeutic regimens for administration of baff antagonists for treatment of immunologic and related disorder are described. Regimens involve a short-term baff antagonist administration course followed by an extended no-treatment period prior the round or administration..
Biogen Idec Ma Inc.


Modulation of nlgn4 expression, nk cell activity in non-alcoholic fatty liver disease (nafld)


The present invention provides a method of treating, attenuating or preventing a liver disorder by inhibiting nlgn4 expression and thereby modulating the activity of nk cells. The present invention further relates to diagnosing a liver disorder by evaluating nlgn4 expression in nk cells..

Method for treating cell proliferative disorder by inhibiting c1galt1 expression


A method for treating a cell proliferative disorder in a subject is provided. The method for treating a cell proliferative disorder has a step of: administering a c1galt1 inhibition substance to the subject for inhibiting c1galt1 expression or activity in the subject, so as to treat the cell proliferative disorder in the subject..
National Taiwan University


Print management in print-on-demand jobs


A method for managing reproduction of a print generation of a document, where a machine-readable pattern of the original print has been previously generated and printed on the original print and containing document registration and management information of the original print. The method includes the steps of receiving a print-on-demand (pod) job order for producing a reprint of the original print, retrieving document registration information and print management information from the machine-readable pattern, authenticating the original print based on the document registration information, verifying reprint permission based on the print management information, generating a new machine-readable pattern for the reprint, maintaining a master machine-readable pattern on a digital form of the document or a data file for the document with updated information of the reprint, and completing the pod job order by producing the reprint with the new machine-readable pattern..
Konica Minolta Laboratory U.s.a., Inc.


System for supervising the security of an architecture


A method is provided for supervising security of an architecture having a plurality of interconnected clouds. A cloud includes a plurality of resources and a security supervisor.
Orange


Results from search providers using a browsing-time relevancy factor


A method for searching web pages that begins with the identification of query criteria entered into a search provider. A set of web pages that satisfies the query criteria are determined.
International Business Machines Corporation


Storing and serving images in memory boxes


Images and related data are served from an image server to a client device. A unique identifier and associated parameters for each image are converted into a binary string.
Shutterfly, Inc.


Cancer therapy


The present application relates to compositions and methods for treating a proliferative disorder by administering to a subject a pharmaceutical composition of a dual kinase inhibitor. Catecholic butanes cane serve as dual kinase inhibitors for purposes of methods described herein.
Triact Therapeutics, Inc.


Digital system and estimating non-energy parameters of signal carrier


Navigation satellite receivers have a large number of channels, where phase discriminators and loop filter of a pll operate in phase with data bits and control of numerically controlled oscillator (nco) carried out simultaneously on all channels. Since symbol boundaries for different satellites do not match, there is a variable time delay between the generation of control signals and nco control time.
Topcon Positioning Systems, Inc.


Determining sort order by distance


Included are embodiments for determining sort order. At least one embodiment of a method includes determining a plurality of search results associated with at least one search criteria.
At&t Intellectual Property I, Lp


Method for generating optical pulses and optical pulse generator


The method generally has the steps of propagating a seed wave in an optical fiber; generating a wave of first order by stimulated brillouin scattering of the seed wave in the optical fiber, the wave of first order having a frequency spectrally shifted from the seed wave and being backscattered from the seed wave; propagating the seed wave and the wave of first order in a feedback cavity thereby generating a plurality of waves of higher order, each wave of higher order being cascadely generated by the wave of previous order, each wave of higher order being backscattered and having a frequency spectrally shifted from its corresponding wave of previous order and forming a frequency comb with the seed wave and the wave of first order; the frequency comb generating optical pulses; and propagating the generated optical pulses out of the feedback cavity.. .

Treatment of diseases by concurrently eliciting remyelination effects and immunomodulatory effects using selective rxr agonists


The present specification provides rxr agonists with both remyelination promotion and immunomodulatory activities, compositions comprising such rxr agonists, and methods using such compounds and compositions to treat a demyelination-related disorder by both promoting remyelination of neurons and modulating the immune system.. .
Trustees Of Dartmouth College


Compositions, methods and kits for diagnosing and treating cd206 expressing cell-related disorders


A method of diagnosing a cd206 expressing cell-related disorder by administering a pharmaceutical composition to a subject, the composition including a carrier molecule having a detectable moiety attached thereto. The carrier molecule has a dextran backbone, and at least one receptor substrate conjugated, directly or indirectly, to the dextran backbone, wherein the receptor substrate is chosen so as to specifically bind to cd206.
Ohio State Innovation Foundation


The utility of nematode small molecules


The present invention relates to methods of treating immune disorders and/or inflammation using certain modulator compounds. In one embodiment, the present invention provides a method of treating an immune and inflammatory disorders disorder by administering a composition comprising a therapeutically effective dosage of an ascaroside compound, or a mixture of ascaroside compounds, or a mixture containing at least one ascaroside..
California Institute Of Technology


Methods and compositions for diagnosing and treating mood disorders


The present invention relates to methods of diagnosing, prognosing or treating diseases or disorders in which elevated or reduced levels of aβ protein, including aβ1-42 are prevalent. In particular, the present invention relates to methods of diagnosing, prognosing or treating a major or minor depressive episode/disorder attributed to elevated or reduced levels of aβ protein, including aβ1-42, found particularly in body fluids including whole blood, blood cells, serum, plasma, urine and csf as well as in the brain.
New York University


Accelerated trade matching using speculative parallel processing


An electronic trading system is configured to create speculative orders based on real orders. The speculative order differs from the real order by the price, quantity, or the type of financial instrument.
Chicago Mercantile Exchange


Method of treating an ischemia-reperfusion injury-related disorder by administering gpcr ligands


Disclosed are peptide ligands for g-protein coupled receptors that are useful for treating disorders associated with g-protein coupled receptor activation.. .
Compugen Ltd.


Methods for preventing, treating or diagnosing disorders


The present disclosure relates to a method of treating, ameliorating or preventing a disorder by blocking the signaling pathway of c-met, wherein said method comprises the step of administering a therapeutically effective amount of a composition to a subject in need thereof, which composition contains a lipocalin mutein or a fragment or a variant thereof. In addition, the present disclosure relates to a diagnostic composition suitable for use in, e.g., an immuno-imaging technique to detect the presence of c-met as well as the uses thereof..
Pieris Ag


Scheduling method and recording medium recording scheduling program for substrate processing apparatus


A scheduling method includes a first step where a controller prepares the schedule so that a preliminary processing process and a substrate processing process are performed in that order by a processing unit in common, a second step where, when an abnormality occurs in a substrate processing apparatus in a period from the start of the preliminary processing process to before the start of the substrate processing process, the controller stops the substrate processing process at the processing unit designated in the first step, and a third step where, when the abnormality is resolved, the controller prepares the schedule so that a post-resolution preliminary processing process and the substrate processing process are performed in that order at the processing unit designated in the first step.. .
Dainippon Screen Mfg. Co., Ltd.


Responsive electrical stimulation for movement disorders


An implantable neurostimulator system for treating movement disorders includes a sensor, a detection subsystem capable of identifying episodes of a movement disorder by analyzing a signal received from the sensor, and a therapy subsystem capable of supplying therapeutic electrical stimulation to treat the movement disorder. The system treats movement disorders by detecting physiological conditions characteristic of an episode of symptoms of the movement disorder and selectively initiating therapy when such conditions are detected..
Neuropace, Inc.


Inkjet printer


An inkjet printer is provided with an influence calculation portion and a device control portion. The influence calculation portion calculates an influence indicating a degree of an influence of generation of a satellite on a printing condition.
Riso Kagaku Corporation


Tear film stability


The present invention relates to a method of stabilising a tear film in an individual having an ocular surface inflammatory disorder by providing a compound to an ocular surface of the individual to reduce the synthesis of a cholesterol by a meibum-producing tissue.. .
Newsouth Innovations Pty Limited


Payment processing with dynamic barcodes


A system, method and apparatus for payment processing using dynamic barcodes is provided. In an embodiment, a method is provided.

Plod2 as a target of intervention for sarcoma metastasis


The invention provides compositions and methods for treating a disease or disorder by lowering the level of plod2 in a subject.. .

Digital phase locked loop with hybrid delta-sigma phase/frequency detector


A pll includes independent frequency-locking and phase-locking operational modes. In addition, the pll includes a hybrid (e.g., mixed-analog/digital signal) 2nd-order delta-sigma (ds) phase/frequency detector.

Methods for dynamic discounting


The subject invention relates to electronic buying and selling systems and methods. In particular, the invention concerns relations among distinct price curves, price curve attributes (i.e., factors of the offer that can affect the price curves) and buyers or potential buyers.

Medication preparation queue


Methods for managing preparation of a medication for a patient are provided. In one aspect, a method includes receiving information indicative of an order for medication for a patient from an electronic data feed, and determining whether the order for medication for the patient can be filled with a returned medication.

Epigenetic markers for detection of autism spectrum disorders


Methods for determining if a patient has, or is at risk of having, and autism spectrum disorder by detecting epigenetic changes in the genome of the patient. For example, a method can comprise determining the methylation status of one or more genes in a blood sample..

Card drafting and trading system and method


A method of drafting and trading cards includes providing a box of hidden cards, a computer system operating a draft, and a plurality of openings in the draft available for acquisition by users. The users acquire the openings in the draft and are arranged in spots within a draft order by the computer system.

Article processing apparatus, generation method and computer-readable storage medium


An article processing apparatus having a movable member for processing an article, includes an information processor configured to generate a transition order of states of the movable member. The information processor is configured to respectively set a plurality of clusters each including, as a plurality of nodes, a plurality of states that the movable member may take, with respect to a plurality of regions of the article, respectively set a plurality of costs with respect to a plurality of combinations of two nodes respectively belonging to two clusters different from each other of the plurality of clusters, and generate the transition order by obtaining, based on the plurality of clusters and the plurality of costs, as a solution of a traveling salesman problem, an order of traveling a plurality of nodes obtained by selecting one node from each of the plurality of clusters..

Fusion protein


A new fusion protein which can specifically suppress the autoantibodies, which can effectively prevent or treat the autoimmune disease of autoantibody type, and which can be expressed in an amount sufficient for industrial production. A fusion protein, characterized in that, a protein (x) containing a site recognized by autoantibodies which are a cause of the autoimmune disease of autoantibody type is connected to a protein (a) containing a fragment of the antibody heavy chain constant region which exhibits the antibody-dependent cellular cytotoxicity with a linker peptide (l) consisting of one or more amino acid(s), wherein the protein (x), the linker peptide (l) and the protein (a) are connected in this order by means of peptide bond from n terminal to c terminal..



Order By topics:
  • Parathyroid Hormone
  • Mood Disorder
  • Resorption
  • Thyroid Hormone
  • Phosphonate
  • Bisphosphonate
  • Binding Agent
  • Osteoclast
  • Bone Density
  • Bone Resorption
  • Bone Mineral Density
  • Contraindicate
  • Hypercalcemia
  • Hypocalcemia
  • Major Depression


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