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Oma patents



      
           
This page is updated frequently with new Oma-related patent applications. Subscribe to the Oma RSS feed to automatically get the update: related Oma RSS feeds. RSS updates for this page: Oma RSS RSS


Ventricular shunt system and method

Lesion treatment device and methods for treating lesions

Date/App# patent app List of recent Oma-related patents
09/25/14
20140289912
 Peakforce photothermal-based detection of ir nanoabsorption patent thumbnailnew patent Peakforce photothermal-based detection of ir nanoabsorption
An apparatus and method of performing photothermal chemical nanoidentification of a sample includes positioning a tip of a probe at a region of interest of the sample, with the tip-sample separation being less than about 10 nm. Then, ir electromagnetic energy having a selected frequency, ω, is directed towards the tip.
09/25/14
20140289905
 Polypeptides having xylanase activity and polynucleotides encoding same patent thumbnailnew patent Polypeptides having xylanase activity and polynucleotides encoding same
Provided are isolated polypeptides having xylanase activity, catalytic domains and cellulose binding domains, and polynucleotides encoding the polypeptides, catalytic domains or cellulose binding domains. Also provided are nucleic acid constructs, vectors and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides, catalytic domains or cellulose binding domains..
09/25/14
20140289900
 Isolated polynucleotides and polypeptides, and methods of using same for increasing plant yield and/or agricultural characteristics patent thumbnailnew patent Isolated polynucleotides and polypeptides, and methods of using same for increasing plant yield and/or agricultural characteristics
Provided are isolated polynucleotides at least 80% identical to seq id nos: 1-479, 813-5173, 8511, 8513, 8515, 8517, 8519, 8521, 8523, 9096-9141 and 9142; and isolated polypeptides at least 80% homologous to an amino acid sequence selected from the group consisting of seq id nos: 624, 480-623, 625-812, 5174-7015, 7017-7021, 7024, 7026-8510, 8512, 8514, 8516, 8518, 8520, 8522, 8524, 9143-9177, such as the polypeptides set forth in seq id no:480-812, 5174-8510, 8512, 8514, 8516, 8518, 8520, 8522, 8524, and 9143-9177, nucleic acid constructs comprising same, transgenic cells and plants expressing same and methods of using same for increasing yield, biomass, growth rate, vigor, oil content, fiber yield, fiber quality, nitrogen use efficiency, and/or abiotic stress tolerance of a plant.. .
09/25/14
20140289840
 System and method for integrated header, state, rate and content anomaly prevention for session initiation protocol patent thumbnailnew patent System and method for integrated header, state, rate and content anomaly prevention for session initiation protocol
Methods and systems for an integrated solution to the rate based denial of service attacks targeting the session initiation protocol are provided. According to one embodiment, header, state, rate and content anomalies are prevented and network policy enforcement is provided for session initiation protocol (sip).
09/25/14
20140289835
 Devices, systems and methods for security using magnetic field based identification patent thumbnailnew patent Devices, systems and methods for security using magnetic field based identification
Devices, systems and methods are disclosed for determining an electromagnetic signature for authenticating a device, a user, and/or a location. In exemplary embodiments, a magnetometer captures an electromagnetic signature which is then compared with one or more authorized electromagnetic signatures.
09/25/14
20140289712
 Effective lifetime dependency analysis and typestate analysis patent thumbnailnew patent Effective lifetime dependency analysis and typestate analysis
Disclosed are typestate and lifetime dependency analysis methods for identifying bugs in c++ programs. Disclosed are an abstract representation (arc++) that models c++ objects and which makes object creation/destruction, usage, lifetime and pointer operations explicit in the abstract model thereby providing a basis for static analysis on the c++ program.
09/25/14
20140289580
 Method and system to improve link budget of a wireless system patent thumbnailnew patent Method and system to improve link budget of a wireless system
A method and system to improve the link budget of a wireless system using fast hybrid automatic repeat request (harq) protocol. In one embodiment of the invention, the medium access control (mac) logic in a base station determines whether the quality of the communication link with a mobile station is bad.
09/25/14
20140289550
 Integrated clock architecture for improved testing patent thumbnailnew patent Integrated clock architecture for improved testing
A computer system includes a first on-chip controller and a second on-chip controller, both connected to a control element. In normal operation, the first and second on-chip controllers operate in different clock domains.
09/25/14
20140289418
 Methods and systems for planning execution of an application in a cloud computing system patent thumbnailnew patent Methods and systems for planning execution of an application in a cloud computing system
Methods and systems related to planning an execution of an application in a cloud computing system are described herein. The method includes determining whether a workload causes an anomaly associated to the execution of an application.
09/25/14
20140289335
 Method and apparatus of configuring a data broadcast service patent thumbnailnew patent Method and apparatus of configuring a data broadcast service
Disclosed are an apparatus and method of broadcasting a message to one or more servers operating in one or more domains. One example method of operation may include creating a message to be broadcasted via user input provided by a user of a computer interface.
09/25/14
20140289330
new patent System, method and engine for group communication
An engine, system and method for a domain social network that interconnects internet users with at least domains owned by or of interest to those internet users, and that may obtain and/or forward obtained dynamic data regarding those domains automatically, such as by web service or email service. The dynamic data may be used to filter and protect content and data of the respective domains, to protect users by identifying low quality web pages or malicious software or pages, to isolate or improve search results regarding the domain, and/or to improve internet-based transaction flow, such as the creation of advertising..
09/25/14
20140289264
new patent One pass submatch extraction
A method for one pass submatch extraction may include receiving an input string, receiving a regular expression with capturing groups, and converting the regular expression with capturing groups into a finite automaton m to extract submatches. The finite automaton m may be evaluated to determine whether the regular expression belongs to a set of regular expressions for which submatch extraction is implemented by using one pass by determining whether an automaton m′=rev(close(m)) is deterministic.
09/25/14
20140289155
new patent Benefits selection in a benefits administration domain model
In embodiments of the present invention improved capabilities are described for a human resource management platform that includes applications targeted to solve a variety of human resource and benefits administration management problems. Applications of the human resource management platform include business applications such as benefits administration that may provide a single solution for facilitating employee benefits management and organizational efficiencies through automation of benefit management functions, measurement of benefit provider effectiveness, and the like..
09/25/14
20140289154
new patent Interfacing with a benefits administration domain model
In embodiments of the present invention improved capabilities are described for a human resource management platform that includes applications targeted to solve a variety of human resource and benefits administration management problems. Applications of the human resource management platform include business applications such as benefits administration that may provide a single solution for facilitating employee benefits management and organizational efficiencies through automation of benefit management functions, measurement of benefit provider effectiveness, and the like..
09/25/14
20140289153
new patent System initiated pending state authorization in a benefits administration domain model
In embodiments of the present invention improved capabilities are described for a human resource management platform that includes applications targeted to solve a variety of human resource and benefits administration management problems. Applications of the human resource management platform include business applications such as benefits administration that may provide a single solution for facilitating employee benefits management and organizational efficiencies through automation of benefit management functions, measurement of benefit provider effectiveness, and the like..
09/25/14
20140289152
new patent Updating an effective dated benefits administration domain model
In embodiments of the present invention improved capabilities are described for a human resource management platform that includes applications targeted to solve a variety of human resource and benefits administration management problems. Applications of the human resource management platform include business applications such as benefits administration that may provide a single solution for facilitating employee benefits management and organizational efficiencies through automation of benefit management functions, measurement of benefit provider effectiveness, and the like..
09/25/14
20140289151
new patent Querying an effective dated benefits administration domain model
In embodiments of the present invention improved capabilities are described for a human resource management platform that includes applications targeted to solve a variety of human resource and benefits administration management problems. Applications of the human resource management platform include business applications such as benefits administration that may provide a single solution for facilitating employee benefits management and organizational efficiencies through automation of benefit management functions, measurement of benefit provider effectiveness, and the like..
09/25/14
20140289150
new patent Operation of a benefits administration domain model
In embodiments of the present invention improved capabilities are described for a human resource management platform that includes applications targeted to solve a variety of human resource and benefits administration management problems. Applications of the human resource management platform include business applications such as benefits administration that may provide a single solution for facilitating employee benefits management and organizational efficiencies through automation of benefit management functions, measurement of benefit provider effectiveness, and the like..
09/25/14
20140289149
new patent Benefits administration domain model and user interface based on persistence layering
In embodiments of the present invention improved capabilities are described for a human resource management platform that includes applications targeted to solve a variety of human resource and benefits administration management problems. Applications of the human resource management platform include business applications such as benefits administration that may provide a single solution for facilitating employee benefits management and organizational efficiencies through automation of benefit management functions, measurement of benefit provider effectiveness, and the like..
09/25/14
20140289148
new patent User initiated pending state authorization in a benefits administration domain model
In embodiments of the present invention improved capabilities are described for a human resource management platform that includes applications targeted to solve a variety of human resource and benefits administration management problems. Applications of the human resource management platform include business applications such as benefits administration that may provide a single solution for facilitating employee benefits management and organizational efficiencies through automation of benefit management functions, measurement of benefit provider effectiveness, and the like..
09/25/14
20140289146
new patent Repairing employee benefits data in a benefits administration domain model
In embodiments of the present invention improved capabilities are described for a human resource management platform that includes applications targeted to solve a variety of human resource and benefits administration management problems. Applications of the human resource management platform include business applications such as benefits administration that may provide a single solution for facilitating employee benefits management and organizational efficiencies through automation of benefit management functions, measurement of benefit provider effectiveness, and the like..
09/25/14
20140289021
new patent Cross domain integration in product lifecycle management
Cross-domain integration within product lifecycle management can include providing a plurality of finite state machines (fsms), wherein each fsm is associated with one business object of an integration flow between a first enterprise information system and a second enterprise information system. Each fsm defines a plurality of lifecycle states of the associated business object.
09/25/14
20140289003
new patent Methods and systems for detecting anomaly in passenger flow
Methods and systems for detecting an anomaly in a passenger flow towards a transport device. Historical data relating to the passenger flow is aggregated and a forecast passenger flow value for a target time frame is determined based upon the historical data.
09/25/14
20140288994
new patent Cross domain integration in product lifecycle management
Cross-domain integration within product lifecycle management can include providing a plurality of finite state machines (fsms), wherein each fsm is associated with one business object of an integration flow between a first enterprise information system and a second enterprise information system. Each fsm defines a plurality of lifecycle states of the associated business object.
09/25/14
20140288943
new patent Healthcare recall management
Various technologies related to managing a medical device recall are implemented. Automated recall functions can facilitate an efficient and effective recall process.
09/25/14
20140288862
new patent Magnetic compensation circuit and method for compensating the output of a magnetic sensor, responding to changes in a first magnetic field
A solution for compensating a magnetic field sensor to permit detection of a small magnetic field in the presence of a large magnetic field is disclosed. A magnetic field sensor detects the magnetic field which produces an analogue signal then encoded by an analogue to digital converter (adc) into a digital stream.
09/25/14
20140288689
new patent Method for controlling the movement of building members of a tyre in a process for manufacturing tyres for vehicle wheels
Method and apparatus for controlling the movement of building members of a tyre in a process for manufacturing tyres for vehicle wheels includes: providing a first device of a first electromagnetic radiation on a first tyre building member; detecting, during a movement of the first building member, a first image in which the first electromagnetic radiation defines a trajectory followed, in the movement, by the first emitter device; carrying out a first comparison between the first image and one or more first reference data; and generating a first notification signal as a function of the first comparison.. .
09/25/14
20140288673
new patent Method and system for managing distributed computing in automation systems
Method and a system for managing distributing computing suitable for implementation in an automation system are provided, wherein in a first step, a set of program instructions is partitioned into a plurality of unit blocks, where each unit block comprises at least one program instruction and, in a second set, at least one complementary block corresponding to at least one unit block are identified from the remainder of the plurality of unit blocks, where the complementary blocks are identified based on a comparison between read-write access of global variables in the unit block and corresponding complementary blocks and, in another step, the plurality of unit blocks are executed on a set of multiple processors within the automation system such that at least one complementary block is executed in parallel with a corresponding unit block.. .
09/25/14
20140288619
new patent Switched diverter circuits for minimizing heating of an implanted lead and/or providing emi protection in a high power electromagnetic field environment
An energy management system that facilitates the transfer of high frequency energy induced on an implanted lead or a leadwire includes an energy dissipating surface associated with the implanted lead or the leadwire, a diversion or diverter circuit associated with the energy dissipating surface, and at least one non-linear circuit element switch for diverting energy in the implanted lead or the leadwire through the diversion circuit to the energy dissipating surface. In alternate configurations, the switch may be disposed between the implanted lead or the leadwire and the diversion circuit, or disposed so that it electrically opens the implanted lead or the leadwire when diverting energy through the diversion circuit to the energy dissipating surface.
09/25/14
20140288610
new patent Coordinated resuscitation perfusion support
This document relates to systems and techniques for the treatment of a cardiac arrest victim via electromagnetic stimulation of physiologic tissue.. .
09/25/14
20140288609
new patent Coordinated resuscitation perfusion support
This document relates to systems and techniques for the treatment of a cardiac arrest victim via electromagnetic stimulation of physiologic tissue.. .
09/25/14
20140288541
new patent Lesion treatment device and methods for treating lesions
Tissue and vessel treatment devices and respective methods are provided. Devices comprise a flexible treatment layer that comprises a plurality of operable elements configured to be activated to apply the treatment to the obstruction upon bending of the flexible treatment layer beyond a specified curvature threshold and to be de-activated upon a specified decrease of the bending.
09/25/14
20140288535
new patent Intragastric volume occupying device with active agents
An implantable intragastric volume occupying device system is provided which generally includes a volume occupying device and an active agent, for example, a metabolic agent or satiety inducing agent. The volume occupying device may be structured to contain the agent and permit controlled release of the agent to the patient while the volume occupying device is positioned within the patient's stomach.
09/25/14
20140288485
new patent Glaucoma surgery methods and systems
Methods and systems are disclosed for creating an aqueous flow pathway in the trabecular meshwork, juxtacanalicular trabecular meshwork and schlemm's canal of an eye for reducing elevated intraocular pressure. Some embodiments described apparatus and methods useful in photoablation of tissues.
09/25/14
20140288471
new patent Muscle optimization device and method
A device and method are provided for therapy and treatment of biological tissue such as muscle, tendon, and ligament tissue, by use of a device and method in which therapeutic vibrational frequency resonance patterns are transmitted to tissues of a patient. The resonance frequencies originate from many resonance domains, including vitamins, minerals, herbs, amino acids, and fatty acids.
09/25/14
20140288459
new patent Ventricular shunt system and method
A ventricular shunt systems and methods of preventing hydrocephalus are described herein. In one aspect, the ventricular shunt system has at least one pressure sensor that is configured to be selectively electromagnetically coupled to an ex-vivo source of rf energy and is variable in response to the pressure in a patient's ventricle..
09/25/14
20140288398
new patent Compositions and devices for the detection of biomarkers in the gastrointestinal tract and methods for making and using them
In alternative embodiments, the invention provides compositions such as devices, pills, beads, capsules, products of manufacture, particles, microparticles, nanoparticles, gels, liquid gels, liquid gel capsules, capsules, tablets, geltabs, liquids, sprays, emulsions, suspensions, pastes or yogurts, for the detection and isolation of biomarkers, nucleic acids, proteins or peptides, proteoglycans, lipids, fats, sugars or polysaccharides in the gastrointestinal tract for e.g., detecting the presence of particular exogenous or endogenous nucleic acids, e.g., dna or rna, or proteins, in the gastrointestinal tract, for example, to diagnose the presence of an infectious or exogenous agent such as a virus, a fungus, a parasite, a bacteria, intestinal helminths and protozoan parasites, and the like, or a biomarker such as a cancer-causing or cancer-predisposing allele, e.g., mutations of the kras2 oncogene in pancreatic cancer. In alternative embodiments, compositions of the invention comprise magnetic particles such as a magnetically-responsive microparticle or nanoparticle; a superparamagnetic bead or polystyrene bead; a superparamagnetic fine particle; a ferrimagnetic particle; or, a magnetic microsphere, nanosphere, microbead or nanobeads.
09/25/14
20140288338
new patent Methods of upgrading biooil to transportation grade hydrocarbon fuels
The present invention relates to the field of biomass derived fuels. It further relates to thermochemical production of liquids (biooils) from biomass.
09/25/14
20140288331
new patent Process for preparing metal difluorochelatoborates and use as battery electrolytes or additives in electrochemical cells
The invention relates to a process for preparing metal difluorochelatoborates, in which a metal bis(chelato)borate of the formula m[bl2] is reacted with boron trifluoride and a metal fluoride (mf) and/or a metal salt of the chelating ligand (m2l) where m+ is a monovalent cation selected from the group consisting of lithium, sodium, potassium and ammonium nr4+, where r═h, alkyl (c1 to c8) and l is a chelating agent having two terminal oxygen atoms and having the general formula (ii), where: when m=1 and y1 and y2 together with c1 form a carbonyl group, n=0 or 1 and o=0 or 1 and r1 and r2 are each, independently of one another, h or alkyl having from one to eight carbon atoms (c1-c8) and y3, y4 are each, independently of one another, or3 (r3═c1-c8-alkyl), then n or o≠1: p=0 or 1 and when n and o=0, p=1; or y1, y2, y3, y4 are each, independently of one another, or3 (r3═c1-c8-alkyl), m=1, n=0 or 1, o=1 and p=0; or c2 and c3 are members of a 5- or 6-membered aromatic or heteroaromatic ring (with n, o or s as heteroelement) which can optionally be substituted by alkyl, alkoxy, carboxy or nitrile, where r1, r2, y3 and y4 are absent, m=0 or in the case of 1, y1 and y2 together with c1 form a carbonyl group and p is 0 or 1, in an organic, aprotic solvent.. .
09/25/14
20140288326
new patent Novel process
A direct acid catalyzed intermolecular electrocyclic rearrangement process for the preparation of linear and cyclic homoallylic ester and amides. A one step intermolecular electrocyclic rearrangement process includes the step of reacting a beta, gamma-unsaturated aldehyde or ketone, in which the beta, gamma-unsaturation is not part of an aromatic ring, with another aldehyde or a secondary aldimine in the presence of an acid..
09/25/14
20140288311
new patent Bis-quinophthalone pigment and a process for preparing the same
Wherein x1, x2, x3 and x4 are independently h or halogen ,preferably cl or br; r2 is substituent selected from the group consisting of h, c1-c20 straight or branched chain alkyl substituents, aromatic substituents, aliphatic substituents, and combinations thereof.. .
09/25/14
20140288299
new patent Process
The present invention relates to a process for preparing a short oligonucleotide comprising the steps of: (i) preparing a crude mixture comprising the oligonucleotide (ii) subjecting the mixture formed in step (i) to a desalting step; wherein the process does not comprise a chromatographic purification step.. .
09/25/14
20140288298
new patent Method for manufacturing monosaccharides, oligosaccharides, and furfurals from biomass
The present invention provides a method for efficiently producing monosaccharides, oligosaccharides, and furfurals from biomass. A biomass is hydrolyzed under conditions under which monosaccharides, oligosaccharides, and furfurals are produced while continuously supplying an aqueous suspension of the biomass from a supply port of a continuous primary hydrolysis device and moving the suspension through the device.
09/25/14
20140288286
new patent Method of extracting and isolation flavonoids from euphorbia cuneata
The present invention relates to methods to isolate flavonoids from euphorbia cuneata, and a pharmaceutical composition comprising the flavonoids or the extracts or both of them for a use as anti-ulcer agent. The present invention further relates to a method to isolate a compound selected from the group consisting of 4′-methoxy-luteolin-7-o-rhamnoglucoside and/or aromadendrin from euphorbia cuneata..
09/25/14
20140288283
new patent Truncated l1 protein of human papillomavirus type 6
The invention relates to a truncated l1 protein of the human papillomavirus type 6, a virus-like particle consisting of the protein, a vaccine comprising said virus-like particle, and the use of the vaccine in the prevention of condyloma acuminatum or hpv infections.. .
09/25/14
20140288278
new patent Chromatography process for resolving heterogeneous antibody aggregates
Disclosed are methods and processes utilizing multi-modal chromatography as a polishing step to separate heterogeneously charged (basic and acidic) aggregates and other impurities from partially a partially purified bulk product monoclonal antibody product. The resulting chromatographic process provides a scaleable production process that is cost effective and increases the productivity of the purification process over a platform utilizing a combination of anion and cation exchange chromatography to resolve heterogeneous aggregates..
09/25/14
20140288245
new patent High glass transition temperature resin formulations
A curable resin formulation based on the modification of cyanate esters with silsesquioxane resins is provided for use in forming a cured composite structure or layer. More specifically, a resin formulation that generally comprises a silsesquioxane resin component having an equivalent weight of aromatic hydroxyl groups that is greater than 500 and less than 2,000 grams per mole of aromatic hydroxyl groups; a cyanate ester component; and optionally a catalyst is described.
09/25/14
20140288238
new patent Polymer polyol, method for producing the same, and method for producing polyurethane resin
A polymer polyol (i) is provided that is formed of a polyol (a), polymer particles (b) obtained by polymerization of an ethylenically unsaturated compound (b), and an active-hydrogen-containing compound (d) having an aromatic ring and having a number-average molecular weight of 150 to 2,000, wherein a content of (d) is 1 to 20% on the basis of a weight of (b). The polymer polyol of the present invention contains polymer particles having sufficiently small particle diameters, has a low viscosity, and has excellent handleability.
09/25/14
20140288229
new patent Resin composition, and pellet and molded product thereof
A resin composition includes 90 to 50% by weight of (a) a polyamide having 7 or more average carbon atoms per amide functional group and containing no aromatic ring; 10 to 50% by weight of (b) a polyamide having an aromatic ring and being crystalline, based on 100% by weight of the total of the component (a) and the component (b); and 5 to 75 parts by weight of (c) a carbon fiber, based on 100 parts by weight of the polyamide including (a) and (b).. .
09/25/14
20140288221
new patent Aromatic amide compound
M is from 0 to 4.. .
09/25/14
20140288215
new patent Hydrolysis resistant and biodegradable aliphatic-aromatic copolyester resin composition
The present invention relates to an aliphatic-aromatic copolyester resin composition with excellent hydrolysis resistance, wherein an unsaturated compound or an anhydride thereof is introduced into a molecular structure, and specifically, the aliphatic-aromatic copolyester resin composition can be manufactured into all molded products by extrusion, injection and the like, by solving problems with respect to physical properties, processability, reaction rates and water solubility of conventional biological resins.. .
09/25/14
20140288203
new patent Polyethylene wax and brominated polymer in styrenic polymer
A polymer composition containing a polymer component containing styrenic polymer, a brominated vinyl aromatic/butadiene copolymer and a polyethylene wax, concentration of the polyethylene wax is 0.02 to 1.0 weight percent based on weight of the polymer component, the polyethylene wax has average molecular weight of 10,000 g/mol or less than 10,000 g/mol. The polymer composition can be a polymeric foam..
09/25/14
20140288194
new patent Method and apparatus for production of uniformly sized nanoparticles
An apparatus and process for creating uniformly sized, spherical nanoparticles from a solid target. The solid target surface is ablated to create an ejecta event containing nanoparticles moving away from the surface.
09/25/14
20140288193
new patent Method for the simultaneous production of ethanol and a fermented, solid product
The invention relates to a method for the simultaneous production of a fermented, solid product and ethanol comprising the following steps: 1) providing a mixture of milled or flaked or otherwise disintegrated biomass, comprising oligosaccharides and/or polysaccharides and live yeast in a dry matter ratio of from 2:1 to 100:1, and water; 2) fermenting the mixture resulting from step (1) under conditions where the water content in the initial mixture does not exceed 65% by weight, for 1-36 hours at a temperature of about 25-60° c. Under anaerobic conditions; 3) incubating the fermented mixture resulting from step (2) for 0.5-240 minutes at a temperature of about 70-150° c.; and 4) separating wet fermented, solid product from the fermented mixture resulting from step (3); further comprising either a) that the fermentation in step (2) is performed in one or more interconnected paddle worm or continuous worm conveyers with inlet means for the fermentation mixture and additives and outlet means for the ferment as well as control means for rotation speed, temperature and ph, or b) that one or more processing aids are added in any of steps (1), (2) and (3) and further comprising a step of 5) separating crude ethanol from the fermented mixture in step (2) by vacuum and/or in step (3) by vacuum or by injection of steam and condensing the surplus stripping steam.
09/25/14
20140288162
new patent Methods, compositions and screens for therapeutics for the treatment of synovial sarcoma
Methods and compositions are provided for treating human synovial sarcoma (ss). Also provided are screens to identify therapeutics for the treatment of synovial sarcoma.
09/25/14
20140288160
new patent Cleavable lipids
Disclosed herein are novel compounds, pharmaceutical compositions comprising such compounds and related methods of their use. The compounds described herein are useful, e.g., as liposomal delivery vehicles to facilitate the delivery of encapsulated polynucleotides to target cells and subsequent transfection of said target cells, and in certain embodiments are characterized as having one or more properties that afford such compounds advantages relative to other similarly classified lipids..
09/25/14
20140288137
new patent Compositions and methods of treatment of inflammatory skin conditions using allantoin
Embodiments herein provide formulations and methods for treatment of inflammatory skin diseases using allantoin in an amount from about 0.5% to about 15.0% by weight. Inflammatory skin diseases treated by embodiments herein include, without limitation, cutaneous porphyria, sclerodema, epidermolysis bulosa, psoriasis, decubitus ulcers, pressure ulcers, diabetic ulcers, venous stasis ulcers, sickle cell ulcers, ulcers caused by burns, eczema, urticaria, atopic dermatitis, dermatitis herpetiform, contact dermatitis, arthritis, gout, lupus erythematosus, acne, alopecia, carcinomas, psoriasis, rosacea, miliaria, skin infections, post-operative care of incisions, post-operative skin care following any variety of plastic surgery operations, skin care following radiation treatment, care of dry, cracked or aged skin and skin lines as well as other conditions affecting the skin and having an inflammatory component, symptoms thereof, or a combination thereof.
09/25/14
20140288133
new patent 3 -amino- pyrazole derivatives useful against tuberculosis
Wherein: het is a 5 to 10-membered heteroaromatic ring; either x is n and y is cr5; or x is c and y is s; z is selected from n and ch; r1 is selected from h and c1-2alkyl; r2 is selected from h, c1-2alkyl, oh, —ch2oh and c1-2alkoxy; each r3 is independently selected from oh, c1-3alkyl, f, cl, br, nh2, and c1-3alkoxy; r4 is selected from c1-3alkyl and haloc1-3 alkyl; r5 is selected from h, c1-3alkyl and haloc1-3alkyl; r6 and r7 are either i) each independently selected from h, c1-3alkyl and c1-3alkoxy; or ii) r6 and r7 together with the ring to which they are attached form a 9-membered bicylic ring; p is 0-3; and ra is selected from h and c1-3alkyl, compositions containing them, their use in therapy, for example in the treatment of tuberculosis, and methods for the preparation of such compounds, are provided.. .
09/25/14
20140288115
new patent Compositions and methods for treating brain cancer
It is discovered that noscapine is effective in treating temozolomide (tmz)-resistant brain cancer. Provided are compositions and methods of treating brain cancer patients, in particular those that are tmz-resistant.
09/25/14
20140288093
new patent Treatment of proteinopathies
The present disclosure provides technologies relating to lysosomal activation. The disclosure provides several strategies for increasing level and/or activity of lysosomal enzyme, and furthermore demonstrates the surprising applicability of such strategies in the treatment and/or prophylaxis of certain proteinopathies.
09/25/14
20140288075
new patent Isoxazole compound for the treatment of cancer
The use of 5-(2,4-dihydroxy-5-isopropyl-phenyl)-4-(4-morpholin-4-ylmethyl-phenyl)-isoxazole-3-carboxylic acid ethylamide or a tautomer thereof or a pharmaceutically acceptable salt or a hydrate or a solvate for the treatment of cancer of the bladder, the colon, the liver, the lung, the breast, the vagina, the ovaries, the pancreas, the kidney, the stomach, the gastrointestinal tract, the prostate, the head and neck, the peritoneal cavity, the thyroid, the bone, the brain, the central nervous system and/or the blood and/or for the treatment of myelodysplastic syndrome, systemic mastocytosis, von hippel-lindau syndrome, multicentric castleman disease and/or psioriasis.. .
09/25/14
20140288073
new patent Method of treating gastrointestinal stromal tumors
The present invention relates to a method of treating gastrointestinal stromal tumors (gist), especially gist, which is progressing after imatinib therapy or after imatinib and sunitinib therapy, using a combination comprising (a) a c-kit inhibitor and (b) a pi3k inhibitor or fgfr inhibitor.. .
09/25/14
20140288070
new patent Compounds and methods for kinase modulation, and indications therefor
Compounds and salts thereof, formulations thereof, conjugates thereof, derivatives thereof, forms thereof and uses thereof are described. In certain aspects and embodiments, the described compounds or salts thereof, formulations thereof, conjugates thereof, derivatives thereof, forms thereof are active on at least one raf protein kinase.
09/25/14
20140288060
new patent Selective inhibition of malt1 protease by phenothiazine derivatives
Wherein x is n or c; y is s, o, so2, so, nh, co, ch2, ch═ch, ch2═ch2; ( )z is a c1-c5 linear or branched alkyl chain; a is nr3r4, or or5, or het; r1 and r2 in each occurrence are independently selected from —h, —ch3, —oh, —och3, —sch3, —f, —cl, —cf3, —nh2, and —cooh; r3, r4, and r5 are h, or c1-c5 linear or branched alkyl groups, and het is a heterocyclic ring of 5, 6, or 7 members, wherein the ring atoms can be c, o, n, or s, the ring can be saturated or aromatic, and the ring can be substituted with h or c1-c5 linear or branched alkyl groups; or a pharmaceutically acceptable salt, prodrug, enantiomer, diastereomer, racemic mixture, crystalline form, amorphous form, unsolvated form or solvate of said compound. The compound of the invention may further be used in the treatment of malt1-dependent immune diseases..
09/25/14
20140288016
new patent Method of providing an anti-ulcer treatment with extracts and isolated flavonoids from euphorbia cuneata
The present invention relates to methods of isolating flavonoids from euphorbia cuneata, and a pharmaceutical composition comprising the flavonoids or the extracts or both of them for a use as anti-ulcer agent. The present invention further relates to a method of providing an anti-ulcer treatment to an animal in need thereof comprising administering to the animal a compound selected from 4′-methoxy-luteolin-7-o-rhamnoglucoside and aromadendrin.
09/25/14
20140288012
new patent Methods for the prevention and treatment of burn injuries and secondary complications
The disclosure relates to methods for treating a subject suffering from a burn injury or associated complications by administering to the subject an effective amount of an aromatic-cationic peptide. For example, a burn injury may be associated with distant pathophysiological effects, such as hypermetabolism, skeletal muscle dysfunction, and organ damage.
09/25/14
20140288011
new patent Genetic association
This invention is directed in part to methods, assays and/or kits for identifying an individual who has an autoimmune disease (such as rheumatoid arthritis), or who has an altered risk for having or developing the autoimmune disease. The methods in one aspect comprise determining the presence or absence of a nucleic acid variant within the somatostatin receptor type 2 (sstr2) gene in the individual's nucleic acids, wherein the presence of the nucleic acid variant is correlated with having the autoimmune disease or the altered risk.
09/25/14
20140288005
new patent Compound for treatment of alzheimer's disease and familial dementia
An isolated protein is provided for use in treatment of a condition selected from the group consisting of alzheimer's disease, familial danish dementia and familial british dementia in a mammal, including man. The isolated protein is selected from the group consisting of proteins comprising an amino acid sequence having at least 70% identity to residues 90-236 of bri2 from human; and proteins comprising an amino acid sequence having at least 70% identity to any one of the brichos domains of bri2 from human, chimpanzee, bovine, pig, mouse and rat..


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