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Oma patents



      
           
This page is updated frequently with new Oma-related patent applications. Subscribe to the Oma RSS feed to automatically get the update: related Oma RSS feeds. RSS updates for this page: Oma RSS RSS


Distributed network anomaly detection

Distributed network anomaly detection

Method for securing name registries, network access and data communication in id/locator split-base networks

Method for securing name registries, network access and data communication in id/locator split-base networks

Method for securing name registries, network access and data communication in id/locator split-base networks

Systems and methods for cloud-based media play out

Date/App# patent app List of recent Oma-related patents
10/09/14
20140304845
 Alzheimer's disease signature markers and methods of use patent thumbnailAlzheimer's disease signature markers and methods of use
Methods, biomarkers, and expression signatures are disclosed for assessing the disease progression of alzheimer's disease (ad). In one embodiment, bioage (biological age), ndstress (neurodegenerative stress), alz (alzheimer), and inflame (inflammation) are used as biomarkers of ad progression.
10/09/14
20140304813
 Distributed network anomaly detection patent thumbnailDistributed network anomaly detection
A network device may include multiple interfaces, each including a local database to store, in a first group of local records, information associated with a first group of data units sent from or received by a first one of the group of interfaces; a global database to store, in a group of global records, information associated with the first group of data units and information associated with a second group of data units sent from or received by a second one of said group of interfaces. The device may include a processor, to manage the local database and the global database; broadcast at least one of the local records to the second one of the group of interfaces; and analyze each of the local records to identify potential anomalies in the first group of data units..
10/09/14
20140304785
 Method for securing name registries, network access and data communication in id/locator split-base networks patent thumbnailMethod for securing name registries, network access and data communication in id/locator split-base networks
The invention provides a new system for internet security. The internet network system comprises a first edge network 11 that comprises a source host (sh) 12, a first gateway (gw) 13 and a local name server (lns) 14, a logical control network 21 which comprises a domain name registry (dnr) 22 and a host name registry (hnr) 23, a target host (th) 31 in the first edge network 11 or in a second edge network 32 and a global transit network 41 which includes routers 42 to connect the first edge network 11, the logical control network 21; and the second edge network 32..
10/09/14
20140304756
 Systems and methods for cloud-based media play out patent thumbnailSystems and methods for cloud-based media play out
The present disclosure is directed to cloud-based media distribution and management systems, providing pushing of content to regional playout servers geographically dispersed for local rebroadcasting of network based content. Automation may be controlled through a hierarchical system, allowing easy and efficient playlist editing and media control.
10/09/14
20140304640
 Techniques for input of a multi-character compound consonant or vowel and transliteration to another language using a touch computing device patent thumbnailTechniques for input of a multi-character compound consonant or vowel and transliteration to another language using a touch computing device
A technique is presented for fast input of multi-character compound consonants and vowels on a touch computing device. The technique provides for fast input of multi-character compound consonants and vowels by enabling a user to touch an initial character on a first layout of characters, then slide his/her finger in different directions and/or different distances according to a second layout of characters.
10/09/14
20140304561
 Shared fuse wrapper architecture for memory repair patent thumbnailShared fuse wrapper architecture for memory repair
A memory repair mechanism for the memories clustered across the multiple power domains and can be switched on and off independent of each other, thereby enabling low power operation. Enhancements in the shared fuse wrapper architecture enable sharing of a plurality of parallel links connecting the memory blocks of each power domains to the shared fuse wrapper architecture..
10/09/14
20140304556
 Performing automated system tests patent thumbnailPerforming automated system tests
A method, system and program product for performing automated tests on a system under test. A set of test blocks is provided, with each test block triggering at least one user activity on the system under test.
10/09/14
20140304502
 Method and system for obtaining peripheral information, and location proxy server patent thumbnailMethod and system for obtaining peripheral information, and location proxy server
A method for obtaining peripheral information method is disclosed herein and includes steps of: receiving a request for obtaining peripheral information, and the request for obtaining peripheral information includes a connection request for access to a third-party website; obtaining the current location information of a mobile terminal according to the connection request; obtaining a link of the third-party website; obtaining the current location information of a mobile terminal according to the connection request; obtaining a link of the third-party website according to domain name information of the third-party website and the current location information of the mobile terminal; making the mobile terminal jump to a page of the third-party website, so as to obtain peripheral information based on the current location of the mobile terminal and the information is provided by the third-party website.. .
10/09/14
20140304414
 Systems and methods for dynamically expanding load balancing pool patent thumbnailSystems and methods for dynamically expanding load balancing pool
The present application is directed towards systems and methods for configuring and applying autoscaling to a service group of an intermediary device for a domain based server. All the ip addresses resolved by the domain name of the server and that are determined as up will automatically become members of the service group.
10/09/14
20140304403
 Validation of a communication network of an industrial automation and control system patent thumbnailValidation of a communication network of an industrial automation and control system
A unit is disclosed for validating a communication network of an industrial automation and control system. The validation unit can include a planner module configured to store plan data defining a designed communication network of an industrial automation and control system, and a collector module configured to collect effective data defining a deployed communication network of the industrial automation and control system.
10/09/14
20140304386
Routing client requests
Methods and systems for routing client requests are provided. According to one embodiment, a request handling server facilitates servicing of client requests for content published by a content publisher.
10/09/14
20140304370
Providing mobile versions of web resources
A transcoding system (1) comprises a mobile communication device (2) that retrieves a web resource using a mobile communication network (3) and the internet (4) via a transcoder (5). The web resource may comprise a web page specifically encoded for the mobile communication device (2).
10/09/14
20140304367
Systems and methods for media distribution and management
The present disclosure is directed to cloud-based media distribution and management systems, providing pushing of content to regional playout servers geographically dispersed for local rebroadcasting of network based content. Automation may be controlled through a hierarchical system, allowing easy and efficient playlist editing and media control.
10/09/14
20140304344
Systems and methods for email tracking and email spam reduction using dynamic email addressing schemes
An email redirection server handles email sent by subscribers or intended for subscribers, obfuscating the subscriber's identity through replacement of the subscriber's native email address with a proxy address in the message header and forwarding the email with only the proxy address. Acquiring a proxy address includes assignment by the email redirection server of a child domain in the dns namespace for the subscriber's exclusive use.
10/09/14
20140304243
Method and system for managing and securing subsets of data in a large distributed data store
A system groups multiple entities in a large distributed data store (dds), such as directories and files, into a subset called a domain. The domain is treated as a unit for defining policies to detect and treat sensitive data.
10/09/14
20140304222
System and method for a self service portal and automation for internally hosted virtual server resources
A method and apparatus may provision a new computer code file as an update or a new application for end nodes of a cloud computing system. The method and apparatus may receive a computer code file at a repository server via a portal interface to an automation service.
10/09/14
20140304110
Procurement process utilizing a light sensor
A system for managing a procurement process uses an ambient light sensor to detect an operating anomaly regarding at least one light source. A procurement system operatively coupled to the light sensing system receives information indicative of the detected operating anomaly of the at least one light source and, in response thereto, initiates the procurement process to obtain a replacement for the at least one light source..
10/09/14
20140303980
System and method for audio kymographic diagnostics
A system and method for assisting in a determination of one or more maladies associated with a human voice anatomy utilizes voice information acquired over at least two temporally displaced acquisitions. Acquired voice samples, including plural vowel sounds, are digitized and passed through one or more bandpass filters to isolate one or more frequency ranges.
10/09/14
20140303954
Multi agent radio frequency propagation simulator
A method and apparatus for simulating radio frequency propagation paths between radio frequency devices are provided. In an illustrative embodiment, the apparatus comprising a system controller for receiving and processing test data, a data sequencer configured to interact with attenuators and rf devices, and rf paths designed to simulate rf propagation paths.
10/09/14
20140303945
Simulation method for macromolecular material
A computer simulation method for a macromolecular material and filler is disclosed, wherein a polymer model of a macromolecular chain of the macromolecular material and a filler model of the filler are defined; and a molecular dynamics calculation is performed using the filler model and the polymer models disposed in a space in order to compute the thickness of an interface layer between the filler and the macromolecular material. To compute the thickness, the space is partitioned into domains bounded by boundary surfaces; relaxation moduli of the domains are computed; and based on a variation of the relaxation moduli of the domains, the thickness of the interface layer is computed..
10/09/14
20140303909
Ultrasonic meter flow measurement monitoring system
The present invention provides an automated meter station monitoring system for a fluid comprising a processor having algorithms for verifying performance of a fluid flow measurement system. A pressure sensor is operatively connected to the processor to measure the pressure of the fluid.
10/09/14
20140303904
Data processing system and method for chromatograph
Based on three-dimensional data of time, wavelength and intensity acquired with a three-dimensional chromatograph, whether or not the peak-top intensity of the peak of a target component exceeds a predetermined upper limit is determined. If the intensity exceeds the limit, two wavelengths λ1 and λ2 are set in a spectrum passing through the peak top, where λ1 is the peak-top wavelength while λ2 is a wavelength which belongs to the peak and at which the intensity is within a predetermined range.
10/09/14
20140303903
Chromatograph mass spectrometry data processing apparatus
Even when only mass spectra wherein the reproducibility of peak intensities is low are obtained in a mass spectrometry apparatus using, for example, a maldi ion source, the correction of shifts in retention time using tics for a plurality of specimens is performed with good precision. For each mass spectrum, variable scaling is executed which combines such first scaling as to equalize the extent of variations in signal intensity values in one mass spectrum, among different mass spectra, and second scaling for performing weighting according to relative variations in signal intensity values for each mass spectrum (s3).
10/09/14
20140303899
System and method for biometric identification in a vehicle
A computer implemented method for identifying a vehicle occupant including receiving a signal from a plurality of sensors, wherein the signal indicates a measurement of cardiac activity, determining a biomarker based on biometric features of the signal and identifying the vehicle occupant based on the biomarker.. .
10/09/14
20140303896
Method for quantitative definition of direct hydrocarbon indicators
Method for automated and quantitative assessment of multiple direct hydrocarbon indicators (“dhi's”) extracted from seismic data. Dhi's are defined in a quantitative way (33), making possible a method of geophysical prospecting based on quantification of dhi anomalies.
10/09/14
20140303870
Systems and methods for semi-autonomous vehicular convoys
The present invention relates to systems and methods for vehicles to safely closely follow one another through partial automation. Following closely behind another vehicle has significant fuel savings benefits, but is unsafe when done manually by the driver.
10/09/14
20140303784
Substation automation system with dynamic multicast filter
Exemplary embodiments provide substation automation systems for operating a high or medium voltage substation for an electric power transmission or distribution network. The substation automation system includes a multitude of secondary devices, which transmit and receive data from/to each other via multicast packets.
10/09/14
20140303756
Human-machine interface test system
The human-machine interface test system enables the automated testing of vehicle interface systems and consumer electronics devices, replacing testing and validation that previously had required human interaction. The human-machine interface device (hmi test object or device under test) does not need to be altered (via hardware or software modifications or additions) to be able to be tested using the human-machine interface test system.
10/09/14
20140303746
Artificial stomach
A method for surgically placing an artificial stomach in a patient is disclosed. The artificial stomach for replacing the normal stomach of a patient comprises a food reservoir adapted to collect food, an inlet connected to a first opening of the food reservoir and further being adapted to upstream connect to the patient's gastrointestinal tract, and an outlet connected to a second opening of the food reservoir and further being adapted to downstream connect to the patient's gastrointestinal tract..
10/09/14
20140303736
Intersomatic implant
An intersomatic implant to be inserted into the intervertebral space is defined by two adjacent vertebrae, comprising a body having an upper face and a lower face, parallel to each other. The peripheries of the faces are connected by a vertical peripheral wall.
10/09/14
20140303692
Therapeutic laser treatment device
A therapeutic device includes a garment configured to be worn on a user's body over a treatment area. The therapeutic device includes a plurality of therapeutic electromagnetic (em) energy emitting devices, fixed to the garment at locations within the garment for irradiating the treatment area with em energy when the garment is worn over the treatment area.
10/09/14
20140303659
Water enucleation of the prostate
Embodiments of the present invention provide improved methods and apparatus of treating the prostate. In many embodiments, at least a portion of the prostate is enucleated with a water jet, in order to decrease the invasiveness of the surgery.
10/09/14
20140303589
Fixing and carrying device for a disposable absorbent incontinence pad
A fixing and carrying device for a disposable absorbent incontinence pad includes a girdle having a front stomach region, a rear back region and a left-hand and a right-hand side region, and girdle closure elements for detachable closure of the girdle on itself so as to form a continuous hip opening in a hip-circumferential direction, the girdle having respective flap sections extending from the back region and the stomach region in a longitudinal direction toward a crotch region of a user; and closure elements respectively provided on a body-facing side of each flap section and being constructed for interaction with complementary closure elements on a body-averted side of the incontinence pad in a detachably adhesive manner, wherein prior to use of the fixing and carrying device the closure elements are folded in onto the body-facing side of the flap section, and the flap sections are respectively folded in onto the front stomach region and rear back region.. .
10/09/14
20140303543
Intestinal sleeve
A gastrointestinal implant device is anchored in the duodenum and extends beyond the ligament of treitz. All food exiting the stomach is funneled through the device.
10/09/14
20140303523
Multimode sensor devices
The disclosure provides bmds that have multiple device modes depending on operational conditions of the devices, e.g., motion intensity, device placement, and/or activity type, the device modes are associated with various data processing algorithms. In some embodiments, the bmd is implemented as a wrist-worn or arm-worn device.
10/09/14
20140303509
Method and apparatus for non-invasive determination of cardiac output
A non-invasive method and apparatus determines continuously cardiac output by first analysing the trace obtained from an optical sensor which has been scaled and calibrated using an electronic sphygmomanometer. From this the mean arterial pressure and time constant are determined.
10/09/14
20140303492
System for placement of a catheter including a signal-generating stylet
An integrated catheter placement system for accurately placing a catheter within a patient's vasculature is disclosed. In one embodiment, the integrated system comprises a system console, a tip location sensor unit for temporary placement on the patient's chest, and an ultrasound probe.
10/09/14
20140303489
Apparatus and methods for using an electromagnetic transponder in orthopedic procedures
Electromagnetic transponders as markers are used to localize and guide orthopedic procedures including: knee replacement, hip replacement, shoulder replacement, damaged bone reconstruction, and spine surgery, and more particularly, to guide orthopedic surgical navigation and alignment techniques and instruments. For example, the marker could further be used in any number of guides or templates that attach to the bony anatomy; such as a surgical guide, cutting guide, cutting jig, resection block and/or resurfacing guide.
10/09/14
20140303451
Health monitoring apparatus
A health monitoring apparatus is providing, which includes a body section and a housing section that covers the body section. The body section includes a printed circuit board, a flow meter section, a first mouth probe, a second mouth probe, and a non-contact thermometer light guide.
10/09/14
20140303425
Method and apparatus for electromagnetic treatment of cognition and neurological injury
Methods and devices for providing therapeutic electromagnetic field treatment to a subject having a cognitive or neurological condition or injury. Treatment devices can include headwear incorporating electromagnetic treatment delivery devices providing electromagnetic treatment to a user's head area.
10/09/14
20140303417
Process for preparing jet fuel from molecules derived from biomass
The invention relates to a process for preparing jet fuel or jet fuel precursors which comprises the treatment of a charge derived from biomass, the said charge comprising at least one compound chosen from terpenes of formula [ch2═c(ch3)ch═ch2]n, in which n is an integer of from 2 to 12, the carbon chain of which is linear, cyclic or branched, or cyclic or branched terpenes as defined previously, which have been chemically modified by oxidation and/or rearrangement of the carbon backbone, the said process comprising a cycloaddition step (i) followed by a cracking and hydrogenation step (ii).. .
10/09/14
20140303415
High pressure feeding system for a liquid-based biomass to liquid reactor
The present disclosure provides methods to transfer a pressurized slurry of plant-based biomass into a reactor vessel. The methods allow for the transfer of practical-sized pieces of biomass in a slurry pressurized to above about 300 psi..
10/09/14
20140303414
Regeneration of catalytic fast pyrolysis catalyst
Catalyst that is used in the catalytic pyrolysis of biomass is regenerated by oxidation and washing with a liquid to remove minerals and restore catalyst activity and selectivity to aromatics.. .
10/09/14
20140303402
Process for the preparation of sulfonamide compounds
Process for the preparation of known sulfonamides having antibacterial activity applicable on industrial scale, which allows their production in high yields and purity, comprising in particular the step of nucleophile aromatic substitution and oxidation in suitable conditions.. .
10/09/14
20140303379
Luminescent solar concentrator comprising disubstituted benzoselenadiazole compounds
Luminescent solar concentrator (lsc) comprising at least one disubstituted benzoselenadiazole compound having general formula (i): r1, r2, r3, r4 and r5, equal to or different from each other, represent a hydrogen atom; or they are selected from linear or branched c1-c20, preferably c1-c10, alkyl groups, cycloalkyl groups optionally substituted, aryl groups optionally substituted, linear or branched c1-c20, preferably c1-c10, alkoxyl groups, optionally substituted; or r1 and r2, can be possibly bound to each other so as to form, together with the carbon atoms to which they are bound, a cycle or a polycyclic system containing from 3 to 14 carbon atoms, preferably from 4 to 6 carbon atoms, saturated, unsaturated, or aromatic, possibly containing one or more heteroatoms such as, for example, oxygen, sulfur, nitrogen, silicon, phosphorous, selenium; or r3 and r4, can be possibly bound to each other so as to form, together with the carbon atoms to which they are bound, a cycle or a polycyclic system containing from 3 to 14 carbon atoms, preferably from 4 to 6 carbon atoms, saturated, unsaturated, or aromatic, possibly containing one or more heteroatoms such as, for example, oxygen, sulfur, nitrogen, silicon, phosphorous, selenium; or r4 and r5, can be possibly bound to each other so as to form, together with the carbon atoms to which they are bound, a cycle or a polycyclic system containing from 3 to 14 carbon atoms, preferably from 4 to 6 carbon atoms, saturated, unsaturated, or aromatic, possibly containing one or more heteroatoms such as, for example, oxygen, sulfur, nitrogen, silicon, phosphorous, selenium.. .
10/09/14
20140303341
Polyamide resin, preparation method thereof, and article comprising same
The present invention relates to: a polyamide resin which is a copolymer of a mixture comprising (a1) one or more aliphatic diamine monomers selected from c4 to c10 aliphatic diamines, and (a2) one or more aliphatic diamine monomers selected from c11 to c18 aliphatic diamines, and a mixture comprising (b1) one or more aromatic dicarboxylic acid monomers selected from aromatic dicarboxylic acids, and (b2) one or more aliphatic dicarboxylic acid monomers selected from c4 to c14 aliphatic dicarboxylic acids, and has an amine and acid end group number greater than about 0 μeq/g to about 150 μeq/g; a preparation method thereof; and an article comprising the same.. .
10/09/14
20140303335
Diketopyrrolopyrrole polymers for use in organic semiconductor devices
The present invention relates to polymers comprising one or more (repeating) unit(s) of the formula (i) which are characterized in that ar1 and ar1′ are independently of each other are an annulated (aromatic) heterocyclic ring system, containing at least one thiophene ring, which may be optionally substituted by one, or more groups, and their use as organic semiconductor in organic devices, especially in organic photovoltaics (solar cells) and photodiodes, or in a device containing a diode and/or an organic field effect transistor. The polymers according to the invention have excellent solubility in organic solvents and excellent film-forming properties.
10/09/14
20140303292
Spun-dyed meta-type wholly aromatic polyamide fiber
A spun-dyed meta-type wholly aromatic polyamide fiber with small discoloration and fading due to the light exposure, in which the content of the solvent remaining in the fiber is at a certain level or less. Specifically, a spun-dyed meta-type wholly aromatic polyamide fiber, in which the residual solvent content of the fiber is 0.1% by mass or less based on the whole mass of the fiber..
10/09/14
20140303291
Biodegradable resin composition, and biodegradable film
There are disclosed a biodegradable resin composition including a starch (a1), a condensation polymer (a2) of an aliphatic diol and an aliphatic dicarboxylic acid, a non-crystalline polylactic acid-based polymer (b) and an aliphatic aromatic polyester (c), a mass ratio (a1/a2) being from 20/80 to 50/50, a mass ratio of a composition (a) comprising the components other than the components (b) and (c) to the component (b) ((a)/(b)) being from 95/5 to 50/50, and a mass ratio {(a)+(b)}/(c) being from 98/2 to 85/15, and a biodegradable film using the biodegradable resin composition.. .
10/09/14
20140303241
Stilbenoid compound as inhibitor for squamous carcinoma and hepatoma and uses thereof
The present invention provides a series of derivatives of stilbenoid which are useful as new inhibitory agents against head and neck squamous cell carcinoma (hnscc) and hepatoma.. .
10/09/14
20140303228
Biomarkers for amyotrophic lateral sclerosis and methods using the same
The disclosure provides biomarkers of amyotrophic lateral sclerosis (als). The disclosure also provides various methods of using the biomarkers, including methods for diagnosis of als, methods of determining predisposition to als, methods of monitoring progression/regression of als, methods of assessing efficacy of compositions for treating als, methods of screening compositions for activity in modulating biomarkers of als, methods of treating als, as well as other methods based on biomarkers of als..
10/09/14
20140303226
Kcnq channels as therapeutic targets
The present disclosure relates to methods and compositions for modulating the activity of kcnq channels as a means for reducing the effects of aberrant kcnq channel function associated with epilepsy, deafness and arrhythmias including but not limited to, long-qt syndrome (“lqts”), and atrial fibrillation. The present disclosure also relates to the discovery of certain regions of kcnq channels that interact with various channel stimulating molecules such as, atp, and pip2, as well as kcnq channel domains that effect voltage dependant channel activation.
10/09/14
20140303173
Cross-linking composition delivered by iontophoresis, useful for the treatment of keratoconus
An improved formulation of an ophthalmic composition contains riboflavin, as cross-linking agent of corneal collagen, administered by corneal iontophoresis, able to guarantee an increased capacity of permeation of riboflavin of the corneal stroma and therefore greater therapeutic efficacy in the treatment of keratoconus.. .
10/09/14
20140303167
Cdk9 inhibitors in the treatment of midline carcinoma
The present invention relates to a cdk9 inhibitor, especially a selective cdk9 inhibitor, for use in treating, ameliorating and/or preventing midline carcinoma. Also corresponding methods for treating, preventing or ameliorating midline carcinoma are subject of the present invention.
10/09/14
20140303126
Novel quinuclidine derivatives and medicinal compositions containing the same
A compound according to formula (i) wherein z© is a phenyl ring, a c4 to c9 heteroaromatic compound containing one or more heteroatoms, or a naphthalenyl, 5,6,7,8-tetrahydronaphthalenyl or biphenyl group; r1, r2 and r3 each independently represent a hydrogen or halogen atom, or a hydroxy group, or a phenyl, —or4, —sr4, —nr4r5, —nhcor4, —conr4r5, —cn, —no2, —coor4 or —cf3 group, or a straight or branched lower alkyl group which may optionally be substituted, for example, with a hydroxy or alcoxy group, wherein r4 and r5 each independently represent a hydrogen atom, straight or branched lower alkyl group, or together form an alicyclic ring; or r1 and r2 together form an aromatic, alicyclic or heterocyclic ring; n is an integer from 0 to 4; a represents a —ch2—, —ch═cr6, —cr6═ch—, —cr6r7—, —co—, —o—, —s—, —s(o)—, so2 or nr6— group, wherein r6 and r7 each independently represent a hydrogen atom, straight or branched lower alkyl group, or r6 and r7 together form an alicyclic ring; in is an integer from 0 to 8; provided that when m=0, a is not —ch2—; p is an integer from 1 to 2 and the substitution in the azoniabicyclic ring may be in the 2, 3 or 4 position including all possible configurations of the asymmetric carbons; b represents a group of formula (i) or (ii), wherein r10 represents a hydrogen atom, a hydroxy or methyl group; and r8 and r9 each independently represents formulae (a), (b), (c), (d) and wherein r11 represents a hydrogen or halogen atom, or a straight or branched lower alkyl group and q represents a single bond, —ch2—, —ch2—ch2, —o—, —o—ch2—, —s—, —s—ch2— or —ch═ch—, and when (i) or (ii) contain a chiral centre they may represent either configuration; x represents a pharmaceutically acceptable anion of a mono or polyvalent acid, which shows high affinity for muscarinic m3 receptors (hm3).. .
10/09/14
20140303082
Selective gpcr ligands
In the past decade a great deal of structural information for class a-gpcrs (g protein-coupled receptors) has emerged. However, the structural and electronic basis of ligand selectivity for closely related receptor subtypes such as the angiotensin receptors at1ar and at2r, which present completely diverse biological functions in response to the same ligand, is poorly understood.
10/09/14
20140303078
Modulation of pancreatic beta cell proliferation
Work described herein provides, in one embodiment, a method for increasing proliferation or replication of pancreatic beta cells in a subject in need thereof, comprising administering to said subject an effective amount of an agent that increases the level or activity of hepatocellular carcinoma-associated protein td26 (td26), thereby increasing proliferation or replication of pancreatic beta cells. Such an agent may function by, for example, increasing the level of active td26 in the subject or by increasing the functional activity of td26 in the subject..
10/09/14
20140303063
Washing or cleaning agent comprising a hydrogel former
The invention relates to a washing or cleaning agent, wherein use thereof generates hydrogel layers surfaces, comprising a hydrogel former having a molecular weight less than 3500 g/mol, wherein the hydrogel former is water-soluble at concentrations below the minimum gel formation concentration, wherein the minimum gel formation concentration is the concentration at which a yield point of at least 0.05 pa is formed in a binary solution of water and hydrogel former at t=25° c., and wherein said minimum gel formation concentration lies below 2 wt % of hydrogel former, relative to the system consisting of water and hydrogel former. The washing or cleaning agents according to the invention enable the hydrophiliation of surfaces, and the specific and retarded releasing of active substances embedded in the hydrogel layers, such as aromatic substances or antimicrobial active substances, for example..
10/09/14
20140303060
Process for degrading a biofilm on surfaces of objects
Optionally followed by further purification steps, such as ion-exchange chromatography and/or concentration.. .
10/09/14
20140303041
In vitro diagnostic devices for nervous system injury and other neural disorders
The present invention relates to an exemplary in vitro diagnostic (ivd) device used to detect the presence of and/or severity of neural injuries or neuronal disorders in a subject. The ivd device relies on an immunoassay which identifies biomarkers that are diagnostic of neural injury and/or neuronal disorders in a biological sample, such as whole blood, plasma, serum, cerebrospinal fluid (csf).
10/09/14
20140303034
Predicting prognosis in classic hodgkin lymphoma
Predictor genes and methods for determining prognosis in classic hodgkin's lymphoma (chl) are described herein. Expression levels of predictor genes aldh1a1, apol6, b2m, cd300a, cd68, cxcl11, glul, hla-a, hla-c, ifng, il15ra, irf1, lmo2, lyz, prf1, rapgef2, rnf144b, stat1, tnfsf10, wdr83, ccl17, col6a1, and pdgfra are used to derive a score within a prognostic model.
10/09/14
20140303029
Genetic alterations in glioma
Methods and genetic sequences are described for use in determining the diagnosis, subtype, prognosis, and disease course of high-grade gliomas, such as glioblastoma multiforme. One such method includes determining increased expression of at least one gene on a chromosome segment in cells of the glioma, the segment being 17:57,851,812-17:57,973,757; 7:127,892,509-7:127,947,649; 12:33,854-12:264,310; or 19:33,329,393-19:35,322,055; and estimating, based on the expression, a predicted length of survival, a probability of survival, or a predicted response to a therapy for the glioma..
10/09/14
20140303027
Gene expression profiling for the diagnosis of prostate cancer
Methods for diagnosing the presence of a disorder, such as prostate cancer, in a subject are provided, such methods including detecting the relative frequency of expression of rna biomarkers in a biological sample obtained from the subject using ngs technology and comparing the relative levels of expression with predetermined threshold levels. Levels of expression of at least two of the rna biomarkers that are above the predetermined threshold levels are indicative of the presence of prostate cancer in the subject.
10/09/14
20140303026
Compounds for modulating integrin cd11b/cd18
The application describes an assay for the identification of small molecule modulators of integrin cd11b/cd18 and small molecules capable of modulating activity of this receptor. Such compounds may be used in certain embodiments for treating a disease or condition selected from inflammation, immune-related disorders, cancer, ischemia-reperfusion injury, stroke, neointimal thickening associated with vascular injury, bullous pemphigoid, neonatal obstructive nephropathy, and cardiovascular disease, or in other embodiments for the treatment of a disease or condition selected from immune deficiency, acquired immune deficiency syndrome (aids), myeloperoxidase deficiency, wiskott-aldrich syndrome, chronic granulomatous disease, hyper-igm syndromes, leukocyte adhesion deficiency, chediak-higashi syndrome, and severe combined immunodeficiency..
10/09/14
20140303018
Nonalcoholic fatty liver disease (nafld) and nonalcoholic steatohepatitis (nash) biomarkers and uses thereof
Methods, compositions, and kits for determining whether a subject has non-alcoholic fatty liver disease (nafld) are provided. Methods, compositions, and kits for determining whether a subject has non-alcoholic steatosis are also provided.
10/09/14
20140303014
Multiplexed detection with isotope-coded reporters
Some aspects of this invention provide reagents and methods for the sensitive, quantitative and simultaneous detection of target analytes in complex biological samples by liquid chromatography tandem mass spectrometry (lc ms/ms). Some aspects of this invention provide affinity reagents encoded with mass reporters for the sensitive and quantitative translation of an analyte of interest into a mass tag.
10/09/14
20140303008
Colorectal cancer associated circulating nucleic acid biomarkers
The invention provides methods and reagents for diagnosing colorectal cancer that are based on the detection of biomarkers in the circulating nucleic acids from a patient to be evaluated. In some embodiments, the cna biomarkers are polynucleotide fragments, e.g., dna fragments, that are present at an elevated level in blood, e.g., in a serum or plasma sample, of a colorectal cancer patient in comparison to the level in blood, e.g., a serum or plasma sample, obtained from a normal individual who does not have colorectal cancer..


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