|| List of recent Ocular-related patents
Polyurethane microparticles are derived from structural units comprising poly(alkylene oxide) moieties, caprolactone moieties and urethane moieties. The microparticles may include an active agent and have a particle size from 0.1 to 100 microns.
|Solvent cast film sustained release latanoprost implant|
The present invention provides a sustained release latanoprost implant in the form of a thin film comprising latanoprost incorporated in a biodegradable polymer matrix. Preferably, said implant is an intraocular implant comprising a thin film comprising latanoprost incorporated in a biodegradable polymer matrix wherein said implant is configured as a disc or a rolled film that can be inserted into the eye and unrolls to provide a film having a high surface area to volume ratio..
|Image processing device, image pickup device, and image display device|
With an image processing device of the present invention, the image processing device, an image pickup device, and an image display device are provided which can correct a spatial distortion generated in taking and displaying a stereoscopic image, and which can present a high-quality image with a stereoscopic feel. The image processing device comprises an information acquisition unit (20) that obtains disparity information calculated from a stereoscopic image, image-pickup condition information when the stereoscopic image is taken, and display condition information of a display unit that displays the stereoscopic image, and an image processing unit (30) that converts a disparity of the stereoscopic image.
|Eyes-off-the-road classification with glasses classifier|
A method for determining an eyes-off-the-road (eotr) condition exists includes capturing image data corresponding to a driver from a monocular camera device. A detection of whether the driver is wearing eye glasses based on the image data using an eye glasses classifier.
|Compact foldable apparatus for ophthalmology|
There is a need for robust and portable system, and apparatus for ophthalmology. We propose use of folding apparatus for ocular purposes for the first time.
|Monocular telescope capable of capturing and recording images|
The monocular telescope provided by the present invention includes a monocular main body, an image capturing/recording module and a lcd monitor. The monocular main body includes a tube.
|Method for measuring the height profile of a vehicle passing on a road|
A method for measuring a height profile of a vehicle passing on a road, said method comprising the following steps: directing a monocular camera from a point above the road onto the road with an angle of aperture that captures a section of the road from above, recording at least a first image of the passing vehicle by the camera at a first moment in time, recording at least a second image of the passing vehicle by the camera at a second moment in time, generating a movement vector image of the vehicle from an analysis of the optical flow between the first and the second image, and creating the height profile of the vehicle from the movement vector image.. .
|Adjustable toric intraocular lens|
An adjustable astigmatism-reducing intraocular lens includes a toric optic with a long axis. The optic is rotationally coupled to haptics, and a plurality of struts extend between the optic and the haptics.
|Plunger tip coupling device for intraocular lens injector|
The present disclosure is directed to devices, systems, and methods directed to mounting a plunger tip to a plunger of an iol injection device. A plunger tip wrench that is operable to releasably retain a plunger tip may be coupled to a holder extending from an end of the iol injection device to align the plunger tip with the plunger of the iol injection device.
|Pre-loaded iol insertion system|
A system for easily transferring an intraocular lens (iol) from an inserter into a patient's eye. The system includes an inserter handpiece with a holding station for receiving or storing an iol.
|Robust laser cutting methods for ophthalmic surgery|
A method and apparatus for performing ophthalmic laser surgery using a pulsed laser beam is provided. The method includes establishing an initial cutting pattern comprising a plurality of original photodisruption points, establishing an enhanced cutting pattern comprising a plurality of enhanced photodisruption points selected to decrease potential adverse effects due to patient movement and having increased density over a fixed area as compared with the plurality of original photodisruption points, and performing an ocular surgical procedure according to the enhanced cutting pattern.
|Rnai-mediated inhibition of select receptor tyrosine kinases for treatment of pathologic ocular neovascularization-related conditions|
Rna interference is provided for inhibiton of expression of select receptor tyrosine kinase (rtk) targets in ocular neovascularization-related conditions, including those cellular changes resulting from the signal transduction activity of the select rtk targets that lead directly or indirectly to ocular nv, abnormal angiogenesis, retinal vascular permeability, retinal edema, diabetic retinopathy particularly proliferative diabetic retinopathy, diabetic macular edema, exudative age-related macular degeneration, sequela associated with retinal ischemia, and posterior segment neovascularization.. .
|Cyclosporin derivatives for treating ocular and dermal diseases and conditions|
—n═c(r8)(nr9r10), i.e. Amidines wherein r3-r10 is h, alk, ar or (ch2)nar wherein ar is an aryl group and n is an integer of from 1 to 13 or r3 and r4 or r4 and r5 or r5 and r7 or r3 and r7, or r9 and r10, together may be —ch2—ch2— or —ch2—ch2—ch2— and r2 is selected from the group consisting of hydroxyl, lower alkyl and hydroxyl-substituted lower alkyl and r2 is selected from the group consisting of hydroxy and lower alkyl..
|Sustained release intraocular implants and methods for treating ocular neuropathies|
Biocompatible intraocular implants include a beta adrenergic receptor antagonist and a polymer associated with the beta adrenergic receptor antagonist to facilitate release of the beta adrenergic receptor antagonist into an eye for an extended period of time. The beta adrenergic receptor antagonist may be associated with a biodegradable polymer matrix, such as a matrix of a two biodegradable polymers.
|Intraocular lens insertion device|
There is provided an intraocular lens insertion device capable of appropriately regulating the motion of a rear supporting portion during a process of moving an intraocular lens, and reducing the possibility of reoperation being required after the intraocular lens is inserted into an eye. An intraocular lens insertion device 1 comprises a main body 2, and a slider 3 and a plunger 4 that are attached to the main body 2.
|System and method of performing femtosecond laser accomodative capsulotomy|
Disclosed is a system and method for making a first incision in an anterior capsule of a capsular bag, the first incision being less than or equal to approximately 3.5 mm in diameter and making a second incision in the anterior capsule, the second incision being less than or equal to approximately 3.0 mm in diameter. The first incision and the second incision are positioned off-center from a center portion of the anterior capsule.
|Auto-regulation system for intraocular pressure|
A device and system for controlling pressure via fluid exchange in the body is presented. The device and system may be used to control intraocular eye pressure.
|Silk compositions and methods of using same|
The present invention provides for silk-derived compositions for treating a wide variety of ocular conditions. The composition is produced by processing the silk cocoon into a water-based solution (i.e., a dissolved silk), which is then cast into a film.
|Anti-pdgfr-beta antibodies and uses thereof|
The present invention provides antibodies that bind to platelet derived growth factor receptor beta (pdgfr-beta) and methods of using the same. According to certain embodiments of the invention, the antibodies are fully human antibodies that bind to human pdgfr-beta with high affinity.
|Method for the pre-operative selection of an intraocular lens to be implanted in an eye|
A method for the preoperative selection of an intraocular lens to optimise the results of refractive surgery on the eye. On the basis of an eye model comprising the individual biometric parameters of the eye, potentially suitable iols are selected on the basis of their optical parameters such as optical power, asphericity and toricity, and the residual refraction of potentially suitable iols is calculated using ray tracing.
|Vision measurement and training system and method of operation thereof|
A binocular viewer, a method of measuring and training vision that uses a binocular viewer and a vision measurement and training system that employs a computer to control the binocular viewer. In one embodiment, the binocular viewer has left and right display elements and comprises: (1) a variable focal depth optical subsystem located in an optical path between the display elements and a user when the user uses the binocular viewer and (2) a control input coupled to the left and right display elements and the variable focal depth optical subsystem and configured to receive control signals operable to place images on the left and right display elements and vary a focal depth of the variable focal depth optical subsystem.
|Retinal prosthesis techniques|
Apparatus for use with an external non-visible light source is provided. The apparatus comprises an intraocular device configured for implantation in a human eye, and comprising an energy receiver.
|Back loaded iol insertion cartridge|
A rear-loaded injector cartridge for an intraocular lens (iol) having a proximal opening that provides a haptic slot. The haptic slot receives a leading haptic of an iol loaded therein, and temporarily retains the leading haptic while the optic of the iol is inserted into a holding area of the cartridge.
|Intraocular lens insertion device|
A cartridge for an intraocular lens insertion device is disclosed. An example cartridge may include an intraocular lens insertion cartridge body having a distal end and a proximal end and configured to receive an intraocular lens for insertion into a patient's eye through an incision; the intraocular lens insertion cartridge body having an inner surface comprising at least one polymeric material having a hardness greater than about 50d and an elongation at break greater than about 150%; the inner surface of the intraocular lens insertion cartridge body defining an at least partially tapering insertion pathway disposed within the intraocular lens insertion cartridge body and extending from the proximal end to the distal end of the intraocular lens insertion cartridge body..
|Ocular pressure regulation|
Disclosed are devices and methods of treating an ocular disorder including forming a self-sealing incision in a cornea into an anterior chamber of an eye; introducing through the incision a fluid drainage tube having a distal end, a proximal end and a longitudinal, internal lumen extending through the fluid drainage tube, wherein at least the proximal end passes through the anterior chamber; and implanting the distal end of the fluid drainage tube in fluid communication with the suprachoroidal space such that the proximal end of the fluid drainage tube remains in fluid communication with the anterior chamber.. .
|Tromethamine salt of bimatoprost acid in crystalline form, methods for preparation, and methods for use thereof|
The present invention provides tromethamine salt of 7-[3,5-dihydroxy-2-(3-hydroxy-5-phenyl-pent-1-enyl)-cyclopentyl]-hept-5-enoic acid in crystalline and amorphous form. This compound is may also be referred to as “tromethamine salt of bimatoprost acid.” the invention crystalline form is useful for solid ocular implant or topical formulations, utilized in the treatment of various ocular conditions, such as, for example, ocular hypertension..
|Crystalline forms of bimatoprost acid, methods for preparation, and methods for use thereof|
The invention provides new crystalline forms of 7-[3,5-dihydroxy-2-(3-hydroxy-5-phenyl-pent-1-enyl)-cyclopentyl]-hept-5-enoic acid. This compound is commonly referred to as “bimatoprost acid.” the novel crystalline forms are designated forms i, ii, and iii.
The present invention relates a composition comprising diclofenac and salts thereof wherein diclofenac or its salts are present in an amount of 25-200 mg. The composition is suitable for the parenteral administration through intramuscular, intravenous route; also for oral, dermal, subcutaneous, cutaneous, nasal, ocular drops, as rectal suppository, vaginal pessaries, intra-articular, and otic delivery.
|Dual mechanism inhibitors for the treatment of disease|
Provided are compounds that are inhibitors of both rho kinase and of a monoamine transporter (mat) act to improve the disease state or condition. Further provided are compositions comprising the compounds.
|Compounds and methods of use thereof for treating neurodegenerative disorders|
Compounds, compositions, kits and methods for treating conditions related to neurodegeneration or ocular disease, are disclosed.. .
|Ocular drug delivery devices|
A method of forming an ocular delivery device includes exposing a solid, shaped cellulose polymer to a solution including an active pharmaceutical ingredient (api) and a solvent capable of solubilizing the api, wherein the polymer absorbs at least a portion of the solution, including the api and solvent. The method may further include removing at least a portion of the absorbed solvent from the polymer by allowing the absorbed solvent to evaporate from the polymer or by drying the polymer.