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This page is updated frequently with new Ocular Implant-related patent applications. Subscribe to the Ocular Implant RSS feed to automatically get the update: related Ocular RSS feeds. RSS updates for this page: Ocular Implant RSS RSS


Systems and methods for an electrocapillary pump for an intraocular implant

Novartis Ag

Systems and methods for an electrocapillary pump for an intraocular implant

Systems and methods for an electrocapillary positive displacement pump for an intraocular implant

Novartis Ag

Systems and methods for an electrocapillary positive displacement pump for an intraocular implant

Systems and methods for an electrocapillary positive displacement pump for an intraocular implant

Methods and apparatus for delivering ocular implants into the eye


Date/App# patent app List of recent Ocular Implant-related patents
08/20/15
20150230984 
 Systems and methods for a membrane-free electrolysis pump for an intraocular implant patent thumbnailSystems and methods for a membrane-free electrolysis pump for an intraocular implant
A microfluidic pump for implantation proximate an eye of a patient is provided herein. The pump includes a first substrate portion and a second substrate portion adjacent the first and a chamber that has a bottom surface and a top surface provided by the first and second substrate portions.
Novartis Ag


08/20/15
20150230983 
 Systems and methods for an electrocapillary pump for an intraocular implant patent thumbnailSystems and methods for an electrocapillary pump for an intraocular implant
A microfluidic pump for implantation proximate an eye of a patient is disclosed herein. The microfluidic pump includes a first microfluidic actuator and a second microfluidic actuator, each with first and second chambers coupled by a channel.
Novartis Ag


08/20/15
20150230982 
 Systems and methods for an electrocapillary positive displacement pump for an intraocular implant patent thumbnailSystems and methods for an electrocapillary positive displacement pump for an intraocular implant
A microfluidic pump for implantation proximate an eye of a patient is disclosed herein. The microfluidic pump includes a first substrate with a microfluidic actuator that includes a first chamber and a second chamber coupled by a channel, an electrode in each of the chambers, and a slug positioned within the channel.
Novartis Ag


08/13/15
20150223985 
 Methods and  delivering ocular implants  into the eye patent thumbnailMethods and delivering ocular implants into the eye
A method of deploying an ocular implant into schlemm's canal of a human eye including the following steps: inserting a distal tip of a delivery tool within an anterior chamber of the eye through trabecular meshwork of the eye into schlemm's canal of the eye; and advancing an ocular implant through a curved portion and a distal opening of the delivery tool to place a body portion of the ocular implant in schlemm's canal and an inlet portion of the ocular implant in the anterior chamber.. .

08/13/15
20150223984 
 Methods and  delivering ocular implants  into the eye patent thumbnailMethods and delivering ocular implants into the eye
A method of deploying an ocular implant into schlemm's canal of a human eye including the following steps: inserting a distal tip of a delivery tool within an anterior chamber of the eye through trabecular meshwork of the eye into schlemm's canal of the eye; and advancing an ocular implant through a curved portion and a distal opening of the delivery tool to place a body portion of the ocular implant in schlemm's canal and an inlet portion of the ocular implant in the anterior chamber.. .

08/13/15
20150223983 
 Ocular implants with asymmetric flexibility patent thumbnailOcular implants with asymmetric flexibility
An ocular implant having an inlet portion and a schlemm's canal portion distal to the inlet portion, the inlet portion being disposed at a proximal end of the implant and sized and configured to be placed within an anterior chamber of a human eye, the schlemm's canal portion being arranged and configured to be disposed within schlemm's canal of the eye when the inlet portion is disposed in the anterior chamber.. .

07/30/15
20150209276 
 Extended release biodegradable ocular implants patent thumbnailExtended release biodegradable ocular implants
Biodegradable implants sized and suitable for implantation in an ocular region or site and methods for treating ocular conditions. The implants provide an extended release of an active agent at a therapeutically effective amount for a period of time between 50 days and one year, or longer..
Allergan, Inc.


07/02/15
20150182330 
 Intraocular lens having input and output electronics patent thumbnailIntraocular lens having input and output electronics
Systems and methods involving an intraocular implant with input and/or output electronics are described. In some embodiments, the system includes an intraocular lens having at least one optic operably coupled to a haptic, one or more input electronics on the haptic and/or the optic; and one or more output electronics on the haptic and/or the optic for receiving and/or transmitting data..
Strathspey Crown Llc


06/11/15
20150157562 
 Hypotensive lipid-containing biodegradable intraocular implants and related implants patent thumbnailHypotensive lipid-containing biodegradable intraocular implants and related implants
Biocompatible intraocular implants include a prostamide component and a biodegradable polymer that is effective in facilitating release of the prostamide component into an eye for an extended period of time. The prostamide component may be associated with a biodegradable polymer matrix, such as a matrix of a two biodegradable polymers.

05/21/15
20150141348 
 Sustained release sirna for ocular drug delivery patent thumbnailSustained release sirna for ocular drug delivery
The present invention provides an ocular implant comprising sirna complexed with a transfection agent selected from the group consisting of cationic lipids and short cell penetration peptides, wherein said complex is associated with a biocompatible polymer. Said biocompatible polymer comprises a polymeric matrix configured to release said complex into the eye of a patient at therapeutic levels for a time sufficient to treat an ocular condition or disease..
Allergan, Inc.


05/21/15
20150140062 

Methods of treatment of ocular conditions with a sustained drug delivery implant


Intraocular implants may include a corticosteroid and a biodegradable polymer associated with the corticosteroid to facilitate the release of the corticosteroid into an eye for a period of time. In some embodiments, ocular conditions, such as diabetic macular edema can be treated through administration of an intraocular implant including a corticosteroid and a biodegradable polymer associated with the corticosteroid to the eye of a human at a frequency of about once every six months to about once a year..
Allergan, Inc.


05/14/15
20150132358 

Punctal plug with active agent


A method and apparatus for administering an active agent such as a medicine to a subject, uses an ocular implant such as a punctal plug, to which the active agent has been applied. The implant is installed at the eye of the subject for administering the active agent via tissues of the eye..

05/07/15
20150126809 

Ocular implant delivery systems and methods


Described herein are delivery devices and methods of using the devices for delivering an ocular implant into a suprachoroidal space without use of a goniolens. The delivery device includes a handle including a channel extending from a proximal end of the handle to a distal end of the handle, an applier coupled to the handle, the applier including a blunt distal tip and an elongate, flexible wire insertable through a fluid channel of an ocular implant, and a fiber optic image bundle reversibly inserted through the channel such that the fiber optic image bundle extends to a region proximal to the blunt distal tip of the applier..
Transcend Medical, Inc.


04/30/15
20150119787 

Delivering ocular implants into the eye


A method of deploying an ocular implant into schlemm's canal of an eye. The method includes the steps of inserting a distal end of a cannula through a cornea of the eye and into an anterior chamber of the eye, the cannula having a distal opening extending from the distal end and through a side wall; placing the distal opening of the cannula into fluid communication with schlemm's canal; advancing the ocular implant distally through the cannula with a delivery tool engaged with the ocular implant, a proximal portion of the ocular implant engaging the delivery tool proximal to a distal portion of the delivery tool; and disengaging the ocular implant and the delivery tool when the proximal portion of the ocular implant reaches the cannula distal opening.

04/30/15
20150118279 

Prostamide-containing intraocular implants and methods of use thereof


Prostamide-containing intraocular implants that biodegrade in the eye and that are effective for reducing intraocular pressure in an eye for a sustained period. The implants generally contain a prostamide, such as bimatoprost, and at least three distinct biodegradable polymers selected from polylactide and poly(lactide-co-glycolide) polymers and are optimized for placement in and compatibility with the anterior chamber of the eye, particularly the anterior chamber angle.
Allergan, Inc.


04/09/15
20150099805 

Hypotensive lipid-containing biodegradable intraocular implants and related methods


Biocompatible intraocular implants include a prostamide component and a biodegradable polymer that is effective in facilitating release of the prostamide component into an eye for an extended period of time. The prostamide component may be associated with a biodegradable polymer matrix, such as a matrix of a two biodegradable polymers.
Allergan, Inc.


03/26/15
20150087696 

Method of controlling initial drug release of sirna from sustained-release implants


The present invention provides an intraocular implant comprising sirna combined with a excipient effective to retard the initial release of the sirna from an implant, wherein said sirna and excipient is associated with a biocompatible polymer (e.g., a polymeric matrix), configured to release said sirna into the eye of a patient at therapeutic levels for a time sufficient to treat an ocular condition or disease.. .
Allergan, Inc.


03/12/15
20150073549 

Intraocular lens with elastic mask


Intraocular implants and methods of making intraocular implants are provided. The intraocular implant can include a lens body having a lens material and a mask having a mask material.
Acufocus, Inc.


03/05/15
20150065940 

Systems and methods for delivering an ocular implant to the suprachoroidal space within an eye


Delivery devices, systems and methods are provided for inserting an implant into an eye. The delivery or inserter devices or systems can be used to dispose or implant an ocular stent or implant, such as a shunt, in communication with the suprachoroidal space, uveal scleral outflow pathway, uveoscleral outflow path or supraciliary space of the eye.
Glaukos Corporation


02/26/15
20150057595 

Pressure-based flow rate measurement for ocular implants


Described herein is an iop control device for implantation in an eye of a patient, comprising a drainage tube, a pressure-driven flow system, and a flow rate measurement system. The drainage tube includes a drainage lumen in fluid communication with an anterior chamber of the eye.
Alcon Research, Ltd.


02/19/15
20150051699 

Intraocular implants and related kits and methods


Devices, methods and kits are described for reducing intraocular pressure. The devices include a support that is implantable within schlemm's canal and that may restore or maintain at least partial patency of the canal without substantially interfering with transmural or transluminal fluid flow across the canal.
Sight Sciences, Inc.


02/05/15
20150038893 

System for delivering multiple ocular implants


Systems and methods for delivering multiple ocular implants to reduce intraocular pressure are disclosed. The ocular implants can be implanted at multiple sites within a single human eye without requiring removal of the delivery apparatus from the eye.
Glaukos Corporation


02/05/15
20150038612 

Polymers and methods for ophthalmic applications


Novel methods and materials particularly useful for ophthalmic applications and to methods for making and using the same are disclosed herein. More particularly, relatively soft, optically transparent, foldable, high refractive index materials particularly suited for use in the production of intraocular lenses, contact lenses, and other ocular implants and to methods for manufacturing and implanting iols made therefrom are disclosed..
Key Medical Technologies, Inc.


01/22/15
20150025627 

Masked intraocular implants and lenses


Intraocular implants and methods of making intraocular implants are provided. The intraocular implants can improve the vision of a patient, such as by increasing the depth of focus of an eye of a patient.
Acufocus, Inc.


01/22/15
20150025062 

Hcn inhibitors affecting ganglion cell function and visual function


The present invention is directed to a method of enhancing visual function in a subject, comprising administering to the subject in need of such enhancement, a therapeutically effective amount of an inhibitor of a hyperpolarization-activated cyclic nucleotide-gated (hcn) channel. The present invention is also directed to an ocular implant comprising a therapeutically effective amount of the hcn channel inhibitor..
Allergan, Inc.


01/22/15
20150025061 

Gabaa receptor antagonists affecting ganglion cell function and visual acuity


The present invention is directed to a method of enhancing visual acuity in a subject, comprising intravitreally administering to the subject in need of such enhancement, a therapeutically effective amount of an extrasynaptic gabaa receptor antagonist. The present invention is also directed to an ocular implant comprising a therapeutically effective amount of the extrasynaptic gabaa receptor antagonist..
Allergan, Inc.


01/01/15
20150005272 

Methods for reducing or preventing transplant rejection in the eye and intraocular implants for use therefor


Methods for reducing or preventing transplant rejection in the eye of an individual are described, comprising: a) performing an ocular transplant procedure; and b) implanting in the eye a bioerodible drug delivery system comprising an immunosuppressive agent and a bioerodible polymer.. .
Allergan, Inc.


12/25/14
20140379078 

Small aperture (pinhole) intraocular implant to increase depth of focus


The constriction of the incident light rays increases the depth of focus, featuring a pinhole effect. The engagement means may be provided by two handles shaped with curved proximal ends joined to the peripheral edge of said diaphragm and having substantially circular section with a diameter between 80 μm and 800 μm or two handles of the same material as the diaphragm and constituting an extension of this edge, or even one elongated platform whose center is located in the small-diameter circular opening..

12/18/14
20140371308 

Hypotensive lipid-containing biodegradable intraocular implants and related methods


Biocompatible intraocular implants include a prostamide component and a biodegradable polymer that is effective in facilitating release of the prostamide component into an eye for an extended period of time. The prostamide component may be associated with a biodegradable polymer matrix, such as a matrix of a two biodegradable polymers.
Allergan, Inc.


12/11/14
20140364789 

Flow promoting ocular implant device and methods


Disclosed are devices and methods for treatment of eye disease such as glaucoma. Implants are described herein that create a flow field, such as between the anterior chamber and either the supraciliary space or suprachoroidal space.

11/20/14
20140343476 

Ocular implant with intraocular fluid pressure regulation


An ocular implant comprising a shunt and a fluid absorbing conduit for reducing intraocular pressure, and optionally comprising a biodegradable ring.. .

11/20/14
20140341966 

Steroid-containing sustained release intraocular implants and related methods


Biocompatible intraocular implant systems are formulated for discontinuous or intermittent release of therapeutic levels of a therapeutic agent (such as a steroid) to minimize development of side effects associated with continuous or long term use of such agent. The implant system may comprise one or more implant, and preferably, although not necessarily, also contains an auxiliary agent having an activity effective to lessen at least one side effect associated with said therapeutic agent compared to the use of an otherwise identical implant system lacking said auxiliary agent.

11/13/14
20140336724 

Retinal prosthesis


The present invention relates to retinal prostheses, and in particular to the transfer of electrical power and data from outside of the human body to such a prosthesis. The retinal prosthesis comprises: a retinal electrode array implanted in the eye to stimulate the retina.

10/30/14
20140323944 

Methods and delivering ocular implants into the eye


A method of deploying an ocular implant into schlemm's canal of a human eye including the following steps: inserting a distal tip of a delivery tool within an anterior chamber of the eye through trabecular meshwork of the eye into schlemm's canal of the eye; and advancing an ocular implant through a curved portion and a distal opening of the delivery tool to place a body portion of the ocular implant in schlemm's canal and an inlet portion of the ocular implant in the anterior chamber.. .

10/30/14
20140322295 

Steroid-containing sustained release intraocular implants and related methods


Biocompatible intraocular implants include a steroid and an auxiliary agent, where the auxiliary agent is present in an amount sufficient to lessen the severity of at least one side effect compared to the use of an otherwise identical implant lacking said auxiliary agent. The steroid and the auxiliary agent may be present on the same intraocular implant or on different implants.

10/23/14
20140316009 

Intraocular pressure reduction with intracameral bimatoprost implants


The present invention provides a method of treating an ocular condition in an eye of a patient, comprising the step of placing a biodegradable intraocular implant in an eye of the patient, the implant comprising a prostamide and a biodegradable polymer matrix that releases drug at a rate effective to sustain release of an amount of the prostamide from the implant to provide an amount of the prostamide effective to prevent or reduce a symptom of an ocular condition of the eye, wherein said ocular condition is elevated iop and said implant is placed in an intracameral location to dilate the outflow channels of the eye emanating from schlemm's canal.. .

09/25/14
20140288645 

Cell migration inhibition system


Generally, an intraocular implant and methods for treating an ocular condition. In particular, an intraocular implant which implanted between an intraocular lens and the surface of the posterior capsule of the eye inhibits migration of residual lens epithelial cells after cataract surgery by providing structural barriers to reduce posterior capsule opacification of the eye..

09/18/14
20140277432 

In situ adjustable optical mask


Implantable corneal and intraocular implants such as a mask are provided. The mask can improve the vision of a patient, such as by being configured to increase the depth of focus of an eye of a patient.

09/18/14
20140271780 

Prostamide-containing intraocular implant


Prostamide-containing biodegradable intraocular implants, prostamide compounds, prostamide-containing pharmaceutical compositions, and methods for making and using such implants and compositions for the immediate and sustained reduction of intraocular pressure and treatment of glaucoma in an eye of a patient are described.. .

09/18/14
20140264981 

Process for manufacturing an intraocular lens with an embedded mask


Intraocular implants and methods of making intraocular implants are provided. The intraocular implant can include a mask adapted to increase depth of focus.

09/04/14
20140249624 

Intraoperative estimation of intraocular lens power


Apparatus for performing intraocular implant surgery, including surgical apparatus for performing intraocular implant surgery, an autorefraction device associated with the surgical apparatus, wherein the autorefraction device is configured to perform autorefraction on the aphakic eye to provide one or more aphakic refraction measurements, and a processor connected to the autorefraction device, wherein the processor is configured to process the aphakic refraction measurements and provide the user of the apparatus with information regarding the power of the intraocular lens.. .

09/04/14
20140249463 

Ocular implant system and method


A method of treating glaucoma in a human eye by inserting a distal exit port of a cannula at least partially into schlemm's canal of the eye; delivering a dye through the cannula into schlemm's canal; identifying obstructions within schlemm's canal; and delivering an ocular implant through the cannula into schlemm's canal.. .

09/04/14
20140249123 

Extended release biodegradable ocular implants


Biodegradable implants sized and suitable for implantation in an ocular region or site and methods for treating ocular conditions. The implants provide an extended release of an active agent at a therapeutically effective amount for a period of time between 50 days and one year, or longer..

08/21/14
20140236270 

Method and ocular implant for transmission of nerve-stimulation light


An improved prosthesis and method for stimulating vision nerves to obtain a vision sensation that is useful for the patient that has lost vision due to age-related macular degeneration (amd) and retinitis pigmentosa (rp) and other diseases. The present invention utilizes infrared light to cause action potentials in the retinal nerves similar to those which result from rods and cones stimulated by visible light in healthy retinas.

08/21/14
20140234390 

Sustained drug delivery implant


Biocompatible intraocular implants may include a brimonidine free base and a biodegradable polymer associated with the brimonidine free base to facilitate the release of the brimonidine free base into an eye with the polymer matrix lasts a period of time of not more than twice the drug release duration, but more than the drug release duration.. .

08/21/14
20140234389 

Sustained drug delivery implant


Biocompatible intraocular implants may include a brimonidine free base and a biodegradable polymer associated with the brimonidine free base to facilitate the release of the brimonidine free base into an eye with the polymer matrix lasts a period of time of not more than twice the drug release duration, but more than the drug release duration.. .

07/31/14
20140214161 

Ocular implants with asymmetric flexibility


An ocular implant having an inlet portion and a schlemm's canal portion distal to the inlet portion, the inlet portion being disposed at a proximal end of the implant and sized and configured to be placed within an anterior chamber of a human eye, the schlemm's canal portion being arranged and configured to be disposed within schlemm's canal of the eye when the inlet portion is disposed in the anterior chamber.. .

07/31/14
20140213958 

Schlemm's canal devices and improving fluid flow


This disclosure relates generally to methods and devices for an ocular implant which can be positioned in the schlemm's canal of a patient's eye for improving fluid flow, such as aqueous fluid, through the eye. The ocular implant can have a variety of shapes and sizes which can allow the ocular implant to be implanted in the schlemm's canal for applying a force, including a predetermined force, along a part of the schlemm's canal.

07/24/14
20140205649 

Solvent cast film sustained release latanoprost implant


The present invention provides a sustained release latanoprost implant in the form of a thin film comprising latanoprost incorporated in a biodegradable polymer matrix. Preferably, said implant is an intraocular implant comprising a thin film comprising latanoprost incorporated in a biodegradable polymer matrix wherein said implant is configured as a disc or a rolled film that can be inserted into the eye and unrolls to provide a film having a high surface area to volume ratio..

07/17/14
20140199366 

Sustained release intraocular implants and methods for treating ocular neuropathies


Biocompatible intraocular implants include a beta adrenergic receptor antagonist and a polymer associated with the beta adrenergic receptor antagonist to facilitate release of the beta adrenergic receptor antagonist into an eye for an extended period of time. The beta adrenergic receptor antagonist may be associated with a biodegradable polymer matrix, such as a matrix of a two biodegradable polymers.

07/03/14
20140187637 

Tromethamine salt of bimatoprost acid in crystalline form, methods for preparation, and methods for use thereof


The present invention provides tromethamine salt of 7-[3,5-dihydroxy-2-(3-hydroxy-5-phenyl-pent-1-enyl)-cyclopentyl]-hept-5-enoic acid in crystalline and amorphous form. This compound is may also be referred to as “tromethamine salt of bimatoprost acid.” the invention crystalline form is useful for solid ocular implant or topical formulations, utilized in the treatment of various ocular conditions, such as, for example, ocular hypertension..

07/03/14
20140187636 

Crystalline forms of bimatoprost acid, methods for preparation, and methods for use thereof


The invention provides new crystalline forms of 7-[3,5-dihydroxy-2-(3-hydroxy-5-phenyl-pent-1-enyl)-cyclopentyl]-hept-5-enoic acid. This compound is commonly referred to as “bimatoprost acid.” the novel crystalline forms are designated forms i, ii, and iii.

06/19/14
20140172090 

Osmotically actuated fluidic valve


An implantable fluidic valve actuated by osmotic pressure gradient and methods of operating it are provided. The valve includes: an input fluid channel; an output fluid channel in fluid communication with the input fluid channel at an aperture; and a semi-permeable membrane forming a portion of a sealed chamber.

06/19/14
20140171777 

Systems and methods for priming an intraocular pressure sensor in an intraocular implant


An iop monitoring device for implantation in an eye of a patient may include a first tube having a first opening, the first tube being configured to extend into the anterior chamber. An intraocular pressure sensing (iop) device for implantation in an eye of a patient may include a pressure sensor, a pressure sensor cap, and a tube coupled to a chamber inlet.

06/05/14
20140155842 

Apparatus and methods for implanting particulate ocular implants


Apparatus and methods for implanting ocular implants in eyes are provided which include a bent cannula having a lumen extending therethrough, the lumen having a length and a diameter and being configured to receive an ocular implant. The ocular implant is made up of a plurality of substantially uniformly sized particles, preferably a plurality of uniformly sized microspheres, arranged in a one-by-one array along the length of the lumen.

06/05/14
20140155805 

Delivery system for ocular implant


A delivery system is disclosed which can be used to deliver an ocular implant into a target location within the eye via an ab interno procedure. In some embodiments, the implant can provide fluid communication between the anterior chamber and the suprachoroidal or supraciliary space while in an implanted state.

06/05/14
20140155803 

Ocular implant with fluid outflow pathways having microporous membranes


Disclosed are devices, methods and systems for treatment of eye disease such as glaucoma. Implants are described herein that enhance aqueous flow through the normal outflow system of the eye with minimal to no complications.

05/22/14
20140142378 

Ocular implant delivery systems and methods


Described herein are delivery devices and methods of using the devices for delivering an ocular implant into a suprachoroidal space without use of a goniolens. The delivery device includes a handle including a channel extending from a proximal end of the handle to a distal end of the handle, an applier coupled to the handle, the applier including a blunt distal tip and an elongate, flexible wire insertable through a fluid channel of an ocular implant, and a fiber optic image bundle reversibly inserted through the channel such that the fiber optic image bundle extends to a region proximal to the blunt distal tip of the applier..

05/15/14
20140135916 

Flow promoting ocular implant


Disclosed are devices, methods and systems for treatment of eye disease, including open angle glaucoma and narrow angle glaucoma. Implants are described herein that create a directed flow field, such as between the anterior chamber and either the supraciliary space or suprachoroidal space.

05/15/14
20140132922 

Optical angular measurement system for ophthalmic applications and positioning of a toric intraocular lens with increased accuracy


An ophthalmic system for use in performing angular measurements in relation to a patient's eye. The ophthalmic system can include an optical angular measurement device that can provide angular indicia by, for example, projecting an image of an angular measurement reticle onto a patient's eye or by superimposing an image of an angular measurement reticle onto an image of the patient's eye.

05/15/14
20140131905 

Process for manufacturing an intraocular lens


Intraocular implants and methods of making intraocular implants are provided. The intraocular implant can include a mask adapted to increase depth of focus.



Popular terms: [SEARCH]

Ocular Implant topics: Ocular Implant, Intraocular, Anterior Chamber, Ocular Implants, Intraocular Pressure, Anterior Chamber Of The Eye, Implantation, Biodegradable, Drug Delivery System, Bevacizumab, Medical Device, Multiple Stents, Aqueous Humor, Visualization, Instruments

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