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Ocular Implant patents



      

This page is updated frequently with new Ocular Implant-related patent applications.




Date/App# patent app List of recent Ocular Implant-related patents
05/19/16
20160135992 
 Delivery system for ocular implant patent thumbnailDelivery system for ocular implant
A delivery system is disclosed which can be used to deliver an ocular implant into a target location within the eye via an ab interno procedure. In some embodiments, the implant can provide fluid communication between the anterior chamber and the suprachoroidal or supraciliary space while in an implanted state.
Transcend Medical, Inc.


04/21/16
20160106533 
 Reprogrammable tuneable liquid crystal lens intraocular implant and methods therefor patent thumbnailReprogrammable tuneable liquid crystal lens intraocular implant and methods therefor
A reprogrammable intraocular adaptive lens prosthesis apparatus is provided. The apparatus includes a tunable liquid crystal lens (tlcl) encapsulated in the intraocular prosthesis with control electronics and a power source or in the intraocular prosthesis with a control signal receiver while an external control electronics package transmits the control signal.

04/14/16
20160100983 
 Ocular system with anchoring implant and therapeutic agent patent thumbnailOcular system with anchoring implant and therapeutic agent
Ocular implants, delivery devices and methods for treating ocular disorders are disclosed. One method involves inserting an implant on one side of an eye.

03/24/16
20160081920 
 Two-layer ocular implant patent thumbnailTwo-layer ocular implant
The present invention generally relates to local therapies for the eye and, more particularly, to shaped controlled-release ocular implant devices, including methods for making and using such devices, for delivery of therapeutic agents to the eye. A molded two-layer ocular implant comprises a therapeutic agent for treatment or prevention of a disorder of the eye.
Odin Biotech


03/24/16
20160081794 
 In situ adjustable optical mask patent thumbnailIn situ adjustable optical mask
Implantable corneal and intraocular implants such as a mask are provided. The mask can improve the vision of a patient, such as by being configured to increase the depth of focus of an eye of a patient.
Acufocus, Inc.


03/24/16
20160081792 
 Intraocular cell migration inhibition system patent thumbnailIntraocular cell migration inhibition system
Generally, an intraocular implant and methods for treating an ocular condition. In particular, an intraocular implant which implanted between an intraocular lens and the surface of the posterior capsule of the eye inhibits migration of residual lens epithelial cells after cataract surgery by providing structural barriers to reduce posterior capsule opacification of the eye..
Insight Innovations, Llc


03/17/16
20160074418 
 Ocular implant made by a double extrusion proces patent thumbnailOcular implant made by a double extrusion proces
The invention provides biodegradable implants sized for implantation in an ocular region and methods for treating medical conditions of the eye. The implants are formed from a mixture of hydrophilic end and hydrophobic end plga, and deliver active agents into an ocular region without a high burst release..
Allergan, Inc.


02/25/16
20160051406 
 Ocular implants and methods for delivering ocular implants into the eye patent thumbnailOcular implants and methods for delivering ocular implants into the eye
An ocular implant is provided. In some embodiments, the ocular implant includes a body that is curved about a longitudinal central axis and a distal body portion that defines a longitudinal channel including a channel opening.

02/11/16
20160038654 
 Sustained release intraocular implants and methods for treating ocular vasculopathies patent thumbnailSustained release intraocular implants and methods for treating ocular vasculopathies
Biocompatible intraocular implants include an alpha-2 adrenergic receptor agonist and a polymer associated with the alpha-2 adrenergic receptor agonist to facilitate release of the alpha-2 adrenergic receptor agonist into an eye for an extended period of time. The alpha-2 adrenergic receptor agonist may be associated with a biodegradable polymer matrix, such as a matrix of a two biodegradable polymers.
Allergan, Inc.


02/11/16
20160038338 
 Systems and methods for delivering an ocular implant to the suprachoroidal space within an eye patent thumbnailSystems and methods for delivering an ocular implant to the suprachoroidal space within an eye
Delivery devices, systems and methods are provided for inserting an implant into an eye. The delivery or inserter devices or systems can be used to dispose or implant an ocular stent or implant, such as a shunt, in communication with a suprachoroidal space of the eye.
Glaukos Corporation


02/04/16
20160030334 

Biodegradable alpha-2 agonist polymeric implants and therapeutic uses thereof


Biocompatible intraocular implants include an alpha-2 adrenergic receptor agonist and a polymer associated with the alpha-2 adrenergic receptor agonist to facilitate release of the alpha-2 adrenergic receptor agonist into an eye for an extended period of time. The alpha-2 adrenergic receptor agonist may be associated with a biodegradable polymer matrix, such as a matrix of a two biodegradable polymers.
Allergan, Inc.


01/21/16
20160015810 

Injectable combination therapy for eye disorders


The present invention provides composition, methods, and articles of manufacture for treating an eye disorder, e.g., a disorder characterized by macular degeneration, choroidal neovascularization, or retinal neovascularization. One method of the invention comprises the step of: administering first and second therapeutic agents to the subject's eye in a single procedure, wherein the first therapeutic agent provides rapid improvement in the condition of the subject's eye and the second therapeutic agent is administered as a sustained release formulation of the second therapeutic agent.
Potentia Pharmaceuticals, Inc.


01/14/16
20160008354 

Sustained release intraocular implants and methods for preventing retinal dysfunction


Biocompatible intraocular implants include an alpha-2 adrenergic receptor agonist and a polymer associated with the alpha-2 adrenergic receptor agonist to facilitate release of the alpha-2 adrenergic receptor agonist into an eye for an extended period of time. The alpha-2 adrenergic receptor agonist may be associated with a biodegradable polymer matrix, such as a matrix of a two biodegradable polymers.
Allergan, Inc.


12/31/15
20150376125 

Tromethamine salt of bimatoprost acid in crystalline form 1, methods for preparation, and methods for use thereof


The present invention provides tromethamine salt of (z)-7-[3,5-dihydroxy-2-((e)-3-hydroxy-5-phenyl-pent-1-enyl)-cyclopentyl]-hept-5-enoic acid in crystalline form 1 and amorphous form. This compound is may also be referred to as “tromethamine salt of bimatoprost acid.” the invention crystalline form is useful for solid ocular implant or topical formulations, utilized in the treatment of various ocular conditions, such as, for example, ocular hypertension..
Allergan, Inc.


12/24/15
20150366710 

Ocular implants for delivery into the eye


An ocular implant adapted to reside at least partially in a portion of schlemm's canal of an eye. The implant includes a spine extending along a longitudinal axis of the implant, a plurality of curved supports extending from the spine, each support comprising a first end extending from a first location on a first side of the spine and a second end extending from a second location on a second side of the spine, the second location being proximal to the first location, so that each support forms a portion of a helix, the spine and supports defining a volume having a maximum width perpendicular to the longitudinal axis between 0.005 inches and 0.04 inches, the ocular implant being configured to bend preferentially in a preferential bending plane..

12/03/15
20150342726 

Ocular implant insertion apparatus and methods


An ocular implant insertion apparatus that includes a plunger driver that is not manually powered and ocular implant insertion methods. There are a variety of instances where an ocular implant is inserted into the anterior chamber, posterior chamber, cornea, vitreous space and/or other portion of an eye.
Hoya Corporation


12/03/15
20150342725 

Micropatterned intraocular implant


Generally, an intraocular implant having on the external surface a plurality of pattern surface elements disposed in spaced apart relation defining a tortuous pathway adapted to control a flow of fluid, or a flow of particles suspended in a fluid, or inhibits the growth or migration of cells. In particular, an intraocular implant which implanted between an intraocular lens and the surface of the posterior capsule of the eye inhibits growth or migration of residual lens epithelial cells after cataract surgery by providing structural barriers to reduce posterior capsule opacification of the eye..
University Of Florida


10/29/15
20150305856 

Intraocular implant, intraocular implant set and intraocular lens


A support structure is a portion which is used to dispose an intraocular lens (a lens) (in a rear section) inside an eye and is formed separately from the lens. When the lens is attached to the support structure, a configuration is formed which is the same as that of the existing intraocular lens including a lens serving as an eye lens extracted due to the cataract or the like and a portion supporting the lens into an eye.

10/22/15
20150297341 

Valve position detection


A valve system for an ocular implant device includes a boss structure. The boss structure includes an inlet for fluid inflow, and a number of outlets for fluid outflow.
Novartis Ag


10/15/15
20150290033 

Delivering ocular implants into the eye


A method of deploying an ocular implant into schlemm's canal of an eye. The method includes the steps of inserting a distal end of a cannula through a cornea of the eye and into an anterior chamber of the eye, the cannula having a distal opening extending from the distal end and through a side wall; placing the distal opening of the cannula into fluid communication with schlemm's canal; advancing the ocular implant distally through the cannula with a delivery tool engaged with the ocular implant, a proximal portion of the ocular implant engaging the delivery tool proximal to a distal portion of the delivery tool; and disengaging the ocular implant and the delivery tool when the proximal portion of the ocular implant reaches the cannula distal opening.

10/08/15
20150282982 

Apparatus for delivering ocular implants into an anterior chamber of the eye


An ocular implant adapted to be disposed within schlemm's canal of a human eye with a body extending along a curved longitudinal central axis in a curvature plane, a first strut on one side of the implant and a second strut on an opposite side of the implant, the circumferential extent of the first strut with respect to the plane of curvature being greater than the circumferential extent of the second strut with respect to the plane of curvature. The invention also includes methods of using the implant..

10/01/15
20150274869 

Nanohybrid polymers for ophthalmic applications


The present invention relates to novel materials particularly useful for ophthalmic applications and methods for making and using the same. More particularly, the present invention relates to relatively soft, optically transparent, foldable, high refractive index materials particularly suited for use in the production of intraocular lenses, contact lenses, and other ocular implants and to methods for manufacturing and using the same..
Key Medical Technologies, Inc.


10/01/15
20150272898 

Oil-in-oil emulsified polymeric implants containing a hypotensive lipid and related methods


Biocompatible intraocular implants, such as microparticles, include a prostamide component and a biodegradable polymer that is effective in facilitating release of the prostamide component into an eye for an extended period of time. The prostamide component may be associated with a biodegradable polymer matrix, such as a matrix of a two biodegradable polymers.
Allergan, Inc.


09/17/15
20150257930 

Debris clearance system for an ocular implant


An iop control system for treatment of an ocular condition includes a drainage device sized for implantation into the eye of the patient, the drainage device including a fluid flow pathway to allow the flow of fluid from an inlet port to an outlet port. The drainage device also includes a flow system disposed within the drainage device and including a displaceable portion forming a part of the fluid flow pathway, the displaceable portion being displaceable via a magnetic field.
Alcon Research, Ltd.


09/10/15
20150250649 

Methods and treating glaucoma


An ocular implant for treating glaucoma is provided, which may include any number of features. More particularly, the present invention relates to implants that facilitate the transfer of fluid from within one area of the eye to another area of the eye.

08/27/15
20150238687 

Intraocular implant delivery apparatus and methods of use thereof


Apparatus and methods for introducing a solid or semi-solid intraocular drug-containing implant into the anterior chamber of an eye are described. The drug-containing implant can be a rod-shaped biodegradable implant that may provide for the extended release of the drug and may be effective for treating a medical condition of the eye.
Allergan, Inc.


08/20/15
20150230984 

Systems and methods for a membrane-free electrolysis pump for an intraocular implant


A microfluidic pump for implantation proximate an eye of a patient is provided herein. The pump includes a first substrate portion and a second substrate portion adjacent the first and a chamber that has a bottom surface and a top surface provided by the first and second substrate portions.
Novartis Ag


08/20/15
20150230983 

Systems and methods for an electrocapillary pump for an intraocular implant


A microfluidic pump for implantation proximate an eye of a patient is disclosed herein. The microfluidic pump includes a first microfluidic actuator and a second microfluidic actuator, each with first and second chambers coupled by a channel.
Novartis Ag


08/20/15
20150230982 

Systems and methods for an electrocapillary positive displacement pump for an intraocular implant


A microfluidic pump for implantation proximate an eye of a patient is disclosed herein. The microfluidic pump includes a first substrate with a microfluidic actuator that includes a first chamber and a second chamber coupled by a channel, an electrode in each of the chambers, and a slug positioned within the channel.
Novartis Ag


08/13/15
20150223985 

Methods and delivering ocular implants into the eye


A method of deploying an ocular implant into schlemm's canal of a human eye including the following steps: inserting a distal tip of a delivery tool within an anterior chamber of the eye through trabecular meshwork of the eye into schlemm's canal of the eye; and advancing an ocular implant through a curved portion and a distal opening of the delivery tool to place a body portion of the ocular implant in schlemm's canal and an inlet portion of the ocular implant in the anterior chamber.. .

08/13/15
20150223984 

Methods and delivering ocular implants into the eye


A method of deploying an ocular implant into schlemm's canal of a human eye including the following steps: inserting a distal tip of a delivery tool within an anterior chamber of the eye through trabecular meshwork of the eye into schlemm's canal of the eye; and advancing an ocular implant through a curved portion and a distal opening of the delivery tool to place a body portion of the ocular implant in schlemm's canal and an inlet portion of the ocular implant in the anterior chamber.. .

08/13/15
20150223983 

Ocular implants with asymmetric flexibility


An ocular implant having an inlet portion and a schlemm's canal portion distal to the inlet portion, the inlet portion being disposed at a proximal end of the implant and sized and configured to be placed within an anterior chamber of a human eye, the schlemm's canal portion being arranged and configured to be disposed within schlemm's canal of the eye when the inlet portion is disposed in the anterior chamber.. .

07/30/15
20150209276 

Extended release biodegradable ocular implants


Biodegradable implants sized and suitable for implantation in an ocular region or site and methods for treating ocular conditions. The implants provide an extended release of an active agent at a therapeutically effective amount for a period of time between 50 days and one year, or longer..
Allergan, Inc.


07/02/15
20150182330 

Intraocular lens having input and output electronics


Systems and methods involving an intraocular implant with input and/or output electronics are described. In some embodiments, the system includes an intraocular lens having at least one optic operably coupled to a haptic, one or more input electronics on the haptic and/or the optic; and one or more output electronics on the haptic and/or the optic for receiving and/or transmitting data..
Strathspey Crown Llc


06/11/15
20150157562 

Hypotensive lipid-containing biodegradable intraocular implants and related implants


Biocompatible intraocular implants include a prostamide component and a biodegradable polymer that is effective in facilitating release of the prostamide component into an eye for an extended period of time. The prostamide component may be associated with a biodegradable polymer matrix, such as a matrix of a two biodegradable polymers.

05/21/15
20150141348 

Sustained release sirna for ocular drug delivery


The present invention provides an ocular implant comprising sirna complexed with a transfection agent selected from the group consisting of cationic lipids and short cell penetration peptides, wherein said complex is associated with a biocompatible polymer. Said biocompatible polymer comprises a polymeric matrix configured to release said complex into the eye of a patient at therapeutic levels for a time sufficient to treat an ocular condition or disease..
Allergan, Inc.


05/21/15
20150140062 

Methods of treatment of ocular conditions with a sustained drug delivery implant


Intraocular implants may include a corticosteroid and a biodegradable polymer associated with the corticosteroid to facilitate the release of the corticosteroid into an eye for a period of time. In some embodiments, ocular conditions, such as diabetic macular edema can be treated through administration of an intraocular implant including a corticosteroid and a biodegradable polymer associated with the corticosteroid to the eye of a human at a frequency of about once every six months to about once a year..
Allergan, Inc.


05/14/15
20150132358 

Punctal plug with active agent


A method and apparatus for administering an active agent such as a medicine to a subject, uses an ocular implant such as a punctal plug, to which the active agent has been applied. The implant is installed at the eye of the subject for administering the active agent via tissues of the eye..

05/07/15
20150126809 

Ocular implant delivery systems and methods


Described herein are delivery devices and methods of using the devices for delivering an ocular implant into a suprachoroidal space without use of a goniolens. The delivery device includes a handle including a channel extending from a proximal end of the handle to a distal end of the handle, an applier coupled to the handle, the applier including a blunt distal tip and an elongate, flexible wire insertable through a fluid channel of an ocular implant, and a fiber optic image bundle reversibly inserted through the channel such that the fiber optic image bundle extends to a region proximal to the blunt distal tip of the applier..
Transcend Medical, Inc.


04/30/15
20150119787 

Delivering ocular implants into the eye


A method of deploying an ocular implant into schlemm's canal of an eye. The method includes the steps of inserting a distal end of a cannula through a cornea of the eye and into an anterior chamber of the eye, the cannula having a distal opening extending from the distal end and through a side wall; placing the distal opening of the cannula into fluid communication with schlemm's canal; advancing the ocular implant distally through the cannula with a delivery tool engaged with the ocular implant, a proximal portion of the ocular implant engaging the delivery tool proximal to a distal portion of the delivery tool; and disengaging the ocular implant and the delivery tool when the proximal portion of the ocular implant reaches the cannula distal opening.

04/30/15
20150118279 

Prostamide-containing intraocular implants and methods of use thereof


Prostamide-containing intraocular implants that biodegrade in the eye and that are effective for reducing intraocular pressure in an eye for a sustained period. The implants generally contain a prostamide, such as bimatoprost, and at least three distinct biodegradable polymers selected from polylactide and poly(lactide-co-glycolide) polymers and are optimized for placement in and compatibility with the anterior chamber of the eye, particularly the anterior chamber angle.
Allergan, Inc.


04/09/15
20150099805 

Hypotensive lipid-containing biodegradable intraocular implants and related methods


Biocompatible intraocular implants include a prostamide component and a biodegradable polymer that is effective in facilitating release of the prostamide component into an eye for an extended period of time. The prostamide component may be associated with a biodegradable polymer matrix, such as a matrix of a two biodegradable polymers.
Allergan, Inc.


03/26/15
20150087696 

Method of controlling initial drug release of sirna from sustained-release implants


The present invention provides an intraocular implant comprising sirna combined with a excipient effective to retard the initial release of the sirna from an implant, wherein said sirna and excipient is associated with a biocompatible polymer (e.g., a polymeric matrix), configured to release said sirna into the eye of a patient at therapeutic levels for a time sufficient to treat an ocular condition or disease.. .
Allergan, Inc.


03/12/15
20150073549 

Intraocular lens with elastic mask


Intraocular implants and methods of making intraocular implants are provided. The intraocular implant can include a lens body having a lens material and a mask having a mask material.
Acufocus, Inc.


03/05/15
20150065940 

Systems and methods for delivering an ocular implant to the suprachoroidal space within an eye


Delivery devices, systems and methods are provided for inserting an implant into an eye. The delivery or inserter devices or systems can be used to dispose or implant an ocular stent or implant, such as a shunt, in communication with the suprachoroidal space, uveal scleral outflow pathway, uveoscleral outflow path or supraciliary space of the eye.
Glaukos Corporation


02/26/15
20150057595 

Pressure-based flow rate measurement for ocular implants


Described herein is an iop control device for implantation in an eye of a patient, comprising a drainage tube, a pressure-driven flow system, and a flow rate measurement system. The drainage tube includes a drainage lumen in fluid communication with an anterior chamber of the eye.
Alcon Research, Ltd.


02/19/15
20150051699 

Intraocular implants and related kits and methods


Devices, methods and kits are described for reducing intraocular pressure. The devices include a support that is implantable within schlemm's canal and that may restore or maintain at least partial patency of the canal without substantially interfering with transmural or transluminal fluid flow across the canal.
Sight Sciences, Inc.


02/05/15
20150038893 

System for delivering multiple ocular implants


Systems and methods for delivering multiple ocular implants to reduce intraocular pressure are disclosed. The ocular implants can be implanted at multiple sites within a single human eye without requiring removal of the delivery apparatus from the eye.
Glaukos Corporation


02/05/15
20150038612 

Polymers and methods for ophthalmic applications


Novel methods and materials particularly useful for ophthalmic applications and to methods for making and using the same are disclosed herein. More particularly, relatively soft, optically transparent, foldable, high refractive index materials particularly suited for use in the production of intraocular lenses, contact lenses, and other ocular implants and to methods for manufacturing and implanting iols made therefrom are disclosed..
Key Medical Technologies, Inc.


01/22/15
20150025627 

Masked intraocular implants and lenses


Intraocular implants and methods of making intraocular implants are provided. The intraocular implants can improve the vision of a patient, such as by increasing the depth of focus of an eye of a patient.
Acufocus, Inc.


01/22/15
20150025062 

Hcn inhibitors affecting ganglion cell function and visual function


The present invention is directed to a method of enhancing visual function in a subject, comprising administering to the subject in need of such enhancement, a therapeutically effective amount of an inhibitor of a hyperpolarization-activated cyclic nucleotide-gated (hcn) channel. The present invention is also directed to an ocular implant comprising a therapeutically effective amount of the hcn channel inhibitor..
Allergan, Inc.


01/22/15
20150025061 

Gabaa receptor antagonists affecting ganglion cell function and visual acuity


The present invention is directed to a method of enhancing visual acuity in a subject, comprising intravitreally administering to the subject in need of such enhancement, a therapeutically effective amount of an extrasynaptic gabaa receptor antagonist. The present invention is also directed to an ocular implant comprising a therapeutically effective amount of the extrasynaptic gabaa receptor antagonist..
Allergan, Inc.


01/01/15
20150005272 

Methods for reducing or preventing transplant rejection in the eye and intraocular implants for use therefor


Methods for reducing or preventing transplant rejection in the eye of an individual are described, comprising: a) performing an ocular transplant procedure; and b) implanting in the eye a bioerodible drug delivery system comprising an immunosuppressive agent and a bioerodible polymer.. .
Allergan, Inc.


12/25/14
20140379078 

Small aperture (pinhole) intraocular implant to increase depth of focus


The constriction of the incident light rays increases the depth of focus, featuring a pinhole effect. The engagement means may be provided by two handles shaped with curved proximal ends joined to the peripheral edge of said diaphragm and having substantially circular section with a diameter between 80 μm and 800 μm or two handles of the same material as the diaphragm and constituting an extension of this edge, or even one elongated platform whose center is located in the small-diameter circular opening..

12/18/14
20140371308 

Hypotensive lipid-containing biodegradable intraocular implants and related methods


Biocompatible intraocular implants include a prostamide component and a biodegradable polymer that is effective in facilitating release of the prostamide component into an eye for an extended period of time. The prostamide component may be associated with a biodegradable polymer matrix, such as a matrix of a two biodegradable polymers.
Allergan, Inc.


12/11/14
20140364789 

Flow promoting ocular implant device and methods


Disclosed are devices and methods for treatment of eye disease such as glaucoma. Implants are described herein that create a flow field, such as between the anterior chamber and either the supraciliary space or suprachoroidal space.

11/20/14
20140343476 

Ocular implant with intraocular fluid pressure regulation


An ocular implant comprising a shunt and a fluid absorbing conduit for reducing intraocular pressure, and optionally comprising a biodegradable ring.. .

11/20/14
20140341966 

Steroid-containing sustained release intraocular implants and related methods


Biocompatible intraocular implant systems are formulated for discontinuous or intermittent release of therapeutic levels of a therapeutic agent (such as a steroid) to minimize development of side effects associated with continuous or long term use of such agent. The implant system may comprise one or more implant, and preferably, although not necessarily, also contains an auxiliary agent having an activity effective to lessen at least one side effect associated with said therapeutic agent compared to the use of an otherwise identical implant system lacking said auxiliary agent.

11/13/14
20140336724 

Retinal prosthesis


The present invention relates to retinal prostheses, and in particular to the transfer of electrical power and data from outside of the human body to such a prosthesis. The retinal prosthesis comprises: a retinal electrode array implanted in the eye to stimulate the retina.

10/30/14
20140323944 

Methods and delivering ocular implants into the eye


A method of deploying an ocular implant into schlemm's canal of a human eye including the following steps: inserting a distal tip of a delivery tool within an anterior chamber of the eye through trabecular meshwork of the eye into schlemm's canal of the eye; and advancing an ocular implant through a curved portion and a distal opening of the delivery tool to place a body portion of the ocular implant in schlemm's canal and an inlet portion of the ocular implant in the anterior chamber.. .

10/30/14
20140322295 

Steroid-containing sustained release intraocular implants and related methods


Biocompatible intraocular implants include a steroid and an auxiliary agent, where the auxiliary agent is present in an amount sufficient to lessen the severity of at least one side effect compared to the use of an otherwise identical implant lacking said auxiliary agent. The steroid and the auxiliary agent may be present on the same intraocular implant or on different implants.



Ocular Implant topics: Ocular Implant, Intraocular, Anterior Chamber, Ocular Implants, Intraocular Pressure, Anterior Chamber Of The Eye, Implantation, Biodegradable, Drug Delivery System, Bevacizumab, Medical Device, Multiple Stents, Aqueous Humor, Visualization, Instruments

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