FreshPatents.com Logo
Enter keywords:  

Track companies' patents here: Public Companies RSS Feeds | RSS Feed Home Page
Popular terms

[SEARCH]

Follow us on Twitter
twitter icon@FreshPatents

Web & Computing
Cloud Computing
Ecommerce
Search patents
Smartphone patents
Social Media patents
Video patents
Website patents
Web Server
Android patents
Copyright patents
Database patents
Programming patents
Wearable Computing
Webcam patents

Web Companies
Apple patents
Google patents
Adobe patents
Ebay patents
Oracle patents
Yahoo patents

[SEARCH]

Nucleotide patents



      
           
This page is updated frequently with new Nucleotide-related patent applications. Subscribe to the Nucleotide RSS feed to automatically get the update: related Nucleotide RSS feeds. RSS updates for this page: Nucleotide RSS RSS


Date/App# patent app List of recent Nucleotide-related patents
05/28/15
20150150157
 Prephenate dehydrogenases and arogenate dehydrogenases that are insensitive to effector feedback inhibition and methods of using the same patent thumbnailnew patent Prephenate dehydrogenases and arogenate dehydrogenases that are insensitive to effector feedback inhibition and methods of using the same
Prephenate dehydrogenases and arogenate dehydrogenase polynucleotide and polypeptide sequences are provided herein. These polypeptides are all insensitive to effector based feedback inhibition.
Wisconsin Alumni Research Foundation
05/28/15
20150149510
 Methods and systems for storing sequence read data patent thumbnailnew patent Methods and systems for storing sequence read data
The present invention generally relates to storing sequence read data. The invention can involve obtaining a plurality of sequence reads from a sample, identifying one or more sets of duplicative sequence reads within the plurality of sequence reads, and storing only one of the sequence reads from each set of duplicative sequence reads in a text file using nucleotide characters..
Good Start Genetics, Inc.
05/28/15
20150148529
 Nucleic acid complex and nucleic acid-polysaccharide complex patent thumbnailnew patent Nucleic acid complex and nucleic acid-polysaccharide complex
As a means for solving the problem of providing a nucleic acid conjugate that does not undergo degradation at a dna-rna bonding site even in vivo, provided is a nucleic acid conjugate comprising a single-stranded dna and a double-stranded rna, wherein the 3′ position of the 3′-terminal deoxyribonucleotide residue of the single-stranded dna is bonded to the 5′ position of the 5′-terminal ribonucleotide residue of one of the ribonucleotide strands of the double-stranded rna, and the hydroxyl group at the 2′ position of the 5′-terminal nucleotide of the ribonucleotide strand, which is bonded to the single-stranded dna, is substituted with an alkoxy group or a halogen atom, and/or the phosphate diester group between the 3′ position of the first ribonucleotide bonded to the single-stranded dna and the 5′ position of the adjacent ribonucleotide is substituted with any of phosphorothioate group, dithiophosphate diester group and trithiophosphate diester group.. .
Japan Science And Technology Agency
05/28/15
20150148528
 Chromatographic purification of polynucleotides with negatively charged particles patent thumbnailnew patent Chromatographic purification of polynucleotides with negatively charged particles
A method of purifying a sample that includes a polynucleotide includes the steps of (i) providing a packed chromatographic column having negatively charged porous particles, (ii) equilibrating the column to the conditions to which the polynucleotide in the sample is to elute, (iii) contacting the sample with the packed chromatographic column such that the sample volume applied to the packed chromatographic column is less than or equal to the interparticle space of the negatively charged porous particles within the packed chromatographic column, (iv) eluting the polynucleotide from the packed chromatographic column, where the polynucleotide is in a purer state and in the conditions to which the packed chromatographic column was equilibrated.. .
Agency For Science, Technology And Research
05/28/15
20150148404
 Rna modulating oligonucleotides with improved characteristics for the treatment of neuromuscular disorders patent thumbnailnew patent Rna modulating oligonucleotides with improved characteristics for the treatment of neuromuscular disorders
The current invention provides an improved oligonucleotide and its use for treating, ameliorating, preventing, delaying and/or treating a human cis-element repeat instability associated genetic neuromuscular or neurodegenerative disorder.. .
Prosensa Technologies B.v.
05/28/15
20150148402
 Modified small interfering rna molecules and methods of use patent thumbnailnew patent Modified small interfering rna molecules and methods of use
The present invention provides double-stranded rna molecules that mediate rna interference in target cells, preferably hepatic cells. The invention also provides double-stranded rna (dsrna) molecules that are modified to be resistant to nuclease degradation, which inactivates a virus, and more specifically, hepatitis c virus (hcv).
Novartis Ag
05/28/15
20150148293
 Fibroblast growth factor mutants having improved functional half-life and methods of their use patent thumbnailnew patent Fibroblast growth factor mutants having improved functional half-life and methods of their use
Mutant fibroblast growth factor (fgf) proteins having a polypeptide sequence with a high sequence identity to proteins encoded by members of the fgf-1 subfamily of genes from a mammalian species, such as human, and with a specific amino acid substitution of an alanine at a position corresponding to amino acid position 66 of human fgf-1 with a cysteine and/or a specific amino acid substitution of a phenylalanine at a position corresponding to amino acid position 132 of human fgf-1 with a tryptophan (based on the 140 amino acid numbering scheme of human fgf-1) are provided. Other amino acid mutations or substitutions may be combined.
Florida State University Research Foundation
05/28/15
20150148291
 Long-acting polypeptides and methods of producing and administering same patent thumbnailnew patent Long-acting polypeptides and methods of producing and administering same
A polypeptide and polynucleotides comprising at least two carboxy-terminal peptides (ctp) of chorionic gonadotrophin attached to a non-human peptide-of-interest are disclosed. Pharmaceutical compositions comprising the non-human polypeptides and polynucleotides of the invention and methods of using both human and non-human polypeptides and polynucleotides are also disclosed..
Opko Biologics Ltd.
05/28/15
20150148288
 Toxic peptide production, peptide expression in plants and combinations of cysteine rich peptides patent thumbnailnew patent Toxic peptide production, peptide expression in plants and combinations of cysteine rich peptides
New insecticidal proteins, nucleotides, peptides, their expression in plants, methods of producing the peptides, new processes, production techniques, new peptides, new formulations, and new organisms, a process which increases the insecticidal peptide production yield from yeast expression systems. The present invention is also related and discloses selected endotoxins we call cysteine rich insecticidal peptides (crips) which are peptides derived from bacillus thuringiensis (bt) and their genes and endotoxins in combination with toxic peptides known as inhibitor cystine knot (ick) genes and peptides as well as with other types of insecticidal peptides such as trypsin modulating oostatic factor (tmof) peptide sequences used in various formulations and combinations; of both genes and peptides, useful for the control of insects..
Vestaron Corporation
05/28/15
20150148263
 Methods for selecting and amplifying polynucleotides patent thumbnailnew patent Methods for selecting and amplifying polynucleotides
The invention provides methods for controlling the density of different molecular species on the surface of a solid support. A first mixture of different molecular species is attached to a solid support under conditions to attach each species at a desired density, thereby producing a derivatized support having attached capture molecules.
Illumina, Inc.
05/28/15
20150148246
new patent

Surface anchored light chain bait antibody display system


The present invention provides, in part, an antibody display system that simultaneously uses a secretion and a display mode. Embodiments of the invention provide a system in which a bait complexed with a monovalent antibody fragment can be captured prior to secretion in a host cell by virtue of surface displaying an antibody light chain and utilizing the covalent interaction of this light chain with the heavy chain of an antibody molecule that is co-expressed in the same host.
Merck Sharp & Dohme Corp.
05/28/15
20150148241
new patent

Method for genome sequencing


The present invention relates to a high throughput method for the identification and detection of molecular markers wherein restriction fragments are generated and suitable adaptors comprising (sample-specific) identifiers are ligated. The adapter-ligated restriction fragments may be selectively amplified with adaptor compatible primers carrying selective nucleotides at their 3′ end.
Keygene N.v.
05/28/15
20150148239
new patent

Spatial molecular barcoding of in situ nucleic acids


This disclosure provides, among other things, a method for analyzing a planar cellular sample. In some embodiments, the method comprises: (a) indirectly or directly attaching nucleic acid tags to binding sites in a planar cellular sample; (b) contacting the planar cellular sample with a solid support comprising an array of spatially addressed features that comprise oligonucleotides, wherein each oligonucleotide comprises a molecular barcode that identifies the feature in which the oligonucleotides is present; (c) hybridizing the nucleic acid tags, or a copy of the same, with the oligonucleotides to produce duplexes; and (d) extending the oligonucleotides in the duplexes to produce extension products that each comprises (i) a molecular barcode and (ii) a copy of a nucleic acid tag.
Agilent Technologies, Inc.
05/28/15
20150147813
new patent

Methods and materials for increasing potency of cells


Disclosed herein are methods and materials for producing a more developmentally potent cell from a less developmentally potent cell. Specifically exemplified herein are methods that comprise introducing an expressible dedifferentiating polynucleotide sequence into a less developmentally potent cell, wherein the transfected less developmentally potent cell becomes a more developmentally potent cell capable of differentiating to a less developmentally potent cell of its lineage of origin or a different lineage..
University Of Central Florida Research Foundation, Inc.
05/28/15
20150147782
new patent

Light-inducible promoter and gene expression system containing same


The present invention relates to a light-inducible promoter and a gene expression system containing the same, and provides: a light-inducible promoter comprising a nucleotide sequence represented by seq id no: 12; and a method for producing heterologous proteins using the same. Since the light-inducible promoter of the present invention induces the expression of a gene by the irradiation of light and regulates an expression amount of the gene according to an intensity of light, it is possible to conveniently regulate the expression of the gene without straining the growth or metabolic process of an organism.
Industry-university Coopertion Foundation Hanyang University
05/28/15
20150147759
new patent

Chimeric oligonucleotides for ligation-enhanced nucleic acid detection, methods and compositions therefor


Ligation-enhanced nucleic acid detection assay embodiments for detection of rna or dna are described. The assay embodiments rely on ligation of chimeric oligonucleotide probes to generate a template for amplification and detection.
Applied Biosystems, Llc
05/28/15
20150147755
new patent

Probe based nucleic acid detection


The invention provides a method for detecting a target nucleotide sequence by tagging the nucleotide sequence with a nucleotide tag, providing a probe oligonucleotide with a melting temperature tm1, comprising a regulatory sequence and a nucleotide tag recognition sequence; incorporating the probe oligonucleotide into the tagged polynucleotide in a polynucleotide amplification reaction, providing a regulatory oligonucleotide with a melting temperature tm2, comprising a sequence segment that is at least partially complementary to the regulatory sequence, amplifying the tagged target nucleic acid sequence in a pcr amplification reaction using the probe oligonucleotide as a primer, and detecting the amplification product; wherein tm1 and tm2 are higher than the annealing temperature associated with the polynucleotide amplification reaction.. .
Fluidigm Corporation
05/28/15
20150147365
new patent

Oral preparation


The present invention relates to an oral composition comprising a volatile sulphur compound breath-odour controlling amount of methyl mercaptan oxidase. The oral composition may be used in a method for controlling breath-odour in a host, which method comprises applying the composition to the oral cavity of that host.
Dsm Ip Assets B.v.
05/28/15
20150147318
new patent

Caninized anti-ngf antibodies and methods thereof


The invention provides novel caninized anti-ngf antibodies (such as caninized anti-ngf antagonist antibodies and antigen binding proteins), and polynucleotides encoding the same. The invention further provides use of said antibodies or antigen binding proteins and/or nucleotides in the treatment and/or prevention of ngf related disorders, particularly pain..
Zoetis Llc
05/28/15
20150147302
new patent

Therapeutically useful molecules


A t cell receptor molecule (tcr) containing an alpha chain portion and a beta chain portion wherein the alpha chain portion contains three complementarity determining regions (cdrs): cdr1α: ssysps cdr2α: ytsaatl cdr3α: vvspf-sgggadglt or comprising or consisting of sppsgggadglt and the beta chain portion contains three complementarity determining regions (cdrs): cdr1β: dfqatt cdr2β: snegska cdr3β: comprising sardggeg or comprising or consisting of rdggegsetqy, or wherein up to three amino acid residues in one or more cdrs are replaced by another amino acid residue. The invention also includes polynucleotides encoding the tcr molecules, and host cells containing the said polynucleotides.
Imperial Innovations Limited
05/21/15
20150143588

Universal donor system for gene targeting


A universal donor polynucleotide is described that can be inserted at targeted locations in plant genomes to facilitate rapid and high throughput integration of a donor molecule within a specific genomic location.. .
Dow Agrosciences Llc
05/21/15
20150143583

Use of the soybean sucrose synthase promoter to increase plant seed lipid content


Recombinant dna constructs comprising the soybean sucrose synthase promoter operably linked to polynucleotides encoding transcription factors such as odp1, lec1 and fusca3 are disclosed. These constructs are used for increasing oil content while maintaining normal germination in oilseed plants.
Pioneer Hi-bred International Inc
05/21/15
20150143581

Nucleic acid molecules and other molecules associated with plants and uses thereof


Polynucleotides useful for improvement of plants are provided. In particular, polynucleotide sequences are provided from plant sources.
Monsanto Technology Llc
05/21/15
20150143580

Compositions and methods for controlling leptinotarsa


Disclosed herein are methods of controlling insect pests, in particular leptinotarsa spp. Which infest crop plants, and methods of providing plants resistant to such pests.
Monsanto Technology Llc
05/21/15
20150143579

Nucleotide sequences and polypeptides encoded thereby useful for modifying plant characteristics


Isolated polynucleotides and polypeptides encoded thereby are described, together with the use of those products for making transgenic plants with increased tolerance to abiotic stress (e.g., high or low temperature, drought, flood).. .
Ceres, Inc.
05/21/15
20150143574

New plant resistance gene


The invention relates to a new gene that is able to provide plants with resistance against pathogens, more preferably verticillium, ralstonia or fusarium. Said gene is typical for brassicaceae and encodes for a proteins having a sequence as depicted in fig.
Stichting Voor De Technische Wetenschappen
05/21/15
20150143563

Isolation of living cells and preparation of cell lines based on detection and quantification of preselected cellular ribonucleic acid sequences


The invention is directed to reliable and efficient detection of mrnas as well as other rnas in living cells and its use to identify and, if desired, separate cells based on their desired characteristics. Such methods greatly simplify and reduce the time necessary to carry out previously-known procedures, and offers new approaches as well, such as selecting cells that generate a particular protein or antisense oligonucleotide, generating cell lines that express multiple proteins, generating cell lines with knock-out of one or more protein, and others..
Chromocell Corporation
05/21/15
20150143556

Mutant alpha-synuclein, and methods using same


The present invention relates to a mutant human alpha-synuclein with increased toxicity compared to wild-type alpha-synuclein, or a homologue thereof, wherein the mutant alpha-synuclein or homologue thereof comprises at least one amino acid substitution selected from the group consisting of a substitution at the alanine at position 56 (a56), at the alanine at position 76 (a76), at the methionine at position 127 (m127) and/or at the valine at position 118 (v118), as defined in the claims. Further, the invention relates to a polynucleotide encoding the mutant alpha-synuclein or homologue thereof, or an expression vector comprising said polynucleotide, a cell comprising the polynucleotide or expression vector, as defined in the claims.
Max-planck-gesellschaft Zur Förderung Der Wissenschaften E.v.
05/21/15
20150141622

Flt4 (vegfr-3) as a target for tumor imaging and anti-tumor therapy


The present invention provide purified flt4 receptor tyrosine kinase polypeptides and fragments thereof, polynucleotides encoding such polypeptides, antibodies that specifically bind such polypeptides, and uses therefor.. .
Vegenics Limited
05/21/15
20150141494

Treatement of vascular endothelial growth factor (vegf) related diseases by inhibition of natural antisense transcript to vegf


Oligonucleotide compounds modulate expression and/or function of vascular endothelial growth factor (vegf) polynucleotides and encoded products thereof. Methods for treating diseases associated with vascular endothelial growth factor (vegf) comprise administering one or more oligonucleotide compounds designed to inhibit the vegf natural antisense transcript to patients..
Curna, Inc.
05/21/15
20150141490

Pyrazolotriazolyl nucleoside analogues and oligonucleotides comprising them


The present invention relates to pyrazolotriazolyl nucleoside analogues, oligonucleotide comprising them, and uses thereof. Further the invention relates to a method for reducing gene expression in a cell comprising transfecting the cell with such an oligonucleotide.
Bio-lab Ltd.
05/21/15
20150141487

Oligoribonucleotides and methods of use thereof for treatment of alopecia, acute renal failure and other diseases


The invention relates to a double-stranded compound, preferably an oligoribonucleotide, which down-regulates the expression of a human p53 gene. The invention also relates to a pharmaceutical composition comprising the compound, or a vector capable of expressing the oligoribonucleotide compound, and a pharmaceutically acceptable carrier.
Quark Pharmaceuticals, Inc.
05/21/15
20150141363

Substituted nucleotide analogs


Disclosed herein are phosphorothioate nucleotide analogs, methods of synthesizing phosphorothioate nucleotide analogs and methods of treating diseases and/or conditions such as viral infections, cancer, and/or parasitic diseases with the phosphorothioate nucleotide analogs.. .
Alios Biopharma, Inc.
05/21/15
20150141331

Long-acting polypeptides and methods of producing and administering same


A polypeptide and polynucleotides comprising at least two carboxy-terminal peptides (ctp) of chorionic gonadotrophin attached to a non-human peptide-of-interest are disclosed. Pharmaceutical compositions comprising the non-human polypeptides and polynucleotides of the invention and methods of using both human and non-human polypeptides and polynucleotides are also disclosed..
Opko Biologics Ltd.
05/21/15
20150141320

Compositions and methods for modulating gene expression


Aspects of the invention provide single stranded oligonucleotides for activating or enhancing expression of a target gene. Further aspects provide compositions and kits comprising single stranded oligonucleotides for activating or enhancing expression of a target gene.
The General Hospital Corporation D/b/a Massachusetts General Hospital
05/21/15
20150141289

Methods and compositions for identifying and validating modulators of cell fate


The invention provides for compositions and methods for identifying and validating modulators of cell fate, such as such as maintenance, cell specification, cell determination, induction of stem cell fate, cell differentiation, cell dedifferentiation, and cell trans-differentiation. The invention relates to reporter nucleic acid constructs, host cells comprising such constructs, and methods using such cells and constructs.
Chromocell Corporation
05/21/15
20150141285

Detection of unlabeled nucleic acids by changing solubility of surface-associating probes


Provided are methods and devices for detection of unlabeled nucleic acids. The detection methods are based on change of solubility of hydrophobic probes upon hybridization with a polynucleotide.
New York University
05/21/15
20150141280

Mirna oncologic biomarker of breast cancer


The invention provides methods of and diagnostic kits for the detection of breast cancer, in particular luminal a breast cancer, or to assist in assessing the prognosis, or determine the efficacy of a treatment regimen for breast cancer comprising at least one oligonucleotide probe capable of binding to at least a portion of a circulating mirna selected from the group comprising the mir-181a and mir-652 biomarkers. The invention also provides methods of identifying a therapeutic agent capable of preventing or treating cancers, including breast cancer, comprising testing the ability of the potential therapeutic agent to enhance the expression of at least one protein selected from the group comprising mir-181a and mir-652..
National University Of Ireland, Galway
05/21/15
20150141277

Methods of quantifying of nucleic acids captured on a solid support


A method for the measurement of the amount or difference in the amounts of 2 or more nucleic acid targets in a sample, the method comprising the steps of attaching to nucleic acids present in the sample (1) a tag which allows the nucleic acids to be captured to a solid support; and (2) a labelled probe for a first nucleic acid target present in the sample and a labelled probe for second nucleic acid target present in the sample, and then measuring the amount of each labelled probe or difference in the amount of labelled probes; wherein the probe is not a single labelled nucleotide.. .
Oxford Technology Limited
05/21/15
20150141272

Ultra-sensitive detection of extremely low level biological analytes using electrochemical signal amplification and biosensor


This invention allows ultra-low levels of virtually any biological analyte to be detected and quantified rapidly, simply and inexpensively with an electrochemical biosensor using a novel electrochemical signal amplification technique. The invention amplifies detection signals from low level analytes using an innovative sandwich elisa structure that replaces optical labels with a massive amount of electrochemically detectable guanine rich oligonucleotide tags.
05/21/15
20150141269

Hybridization-based replication of nucleic acid molecules


The present invention provides methods for replication of nucleic acid molecules distributed on a surface or within a layer by transferring them to a target surface covered with oligonucleotides, and fixation of transferred molecules by hybridization to complementary sequences.. .
Max-planck-gesellschaft Zur FÖrderung Der Wissenschaften E.v.
05/21/15
20150141256

Compositions and methods for bisulfite converted sequence capture


This invention relates generally to composition and methods for characterizing a methylome which comprises all or substantially all methylation states of a genome. In particular, a plurality of oligonucleotides, each representing nearly every possible methylation state of the cytosine position of each cg dinucleotide pair within a target nucleic acid of interest, and methods of using the plurality are provided herein..
Roche Nimblegen, Inc.


Popular terms: [SEARCH]



Follow us on Twitter
twitter icon@FreshPatents

###

This listing is a sample listing of patent applications related to Nucleotide for is only meant as a recent sample of applications filed, not a comprehensive history. There may be associated servicemarks and trademarks related to these patents. Please check with patent attorney if you need further assistance or plan to use for business purposes. This patent data is also published to the public by the USPTO and available for free on their website. Note that there may be alternative spellings for Nucleotide with additional patents listed. Browse our RSS directory or Search for other possible listings.
     SHARE
  
         















0.4173

3916

0 - 1 - 81