FreshPatents.com Logo
Enter keywords:  

Track companies' patents here: Public Companies RSS Feeds | RSS Feed Home Page
Popular terms

[SEARCH]

Follow us on Twitter
twitter icon@FreshPatents

Web & Computing
Cloud Computing
Ecommerce
Search patents
Smartphone patents
Social Media patents
Video patents
Website patents
Web Server
Android patents
Copyright patents
Database patents
Programming patents
Wearable Computing
Webcam patents

Web Companies
Apple patents
Google patents
Adobe patents
Ebay patents
Oracle patents
Yahoo patents

[SEARCH]

Nucleotide patents



      
           
This page is updated frequently with new Nucleotide-related patent applications. Subscribe to the Nucleotide RSS feed to automatically get the update: related Nucleotide RSS feeds. RSS updates for this page: Nucleotide RSS RSS


Date/App# patent app List of recent Nucleotide-related patents
01/29/15
20150033415
 Nucleotide sequences encoding fasciated ear4 (fea4) and methods of use thereof patent thumbnailnew patent Nucleotide sequences encoding fasciated ear4 (fea4) and methods of use thereof
Methods and compositions for modulating shoot apical meristem size are provided. Methods are provided for modulating the expression of fea4 sequence in a host plant or plant cell to modulate agronomic characteristics such as altered size and number of organs, including plant seeds..
E I Dupont De Nemours And Company
01/29/15
20150033411
 Genetically modified plants having improved saccharification properties patent thumbnailnew patent Genetically modified plants having improved saccharification properties
The invention relates to methods for increasing saccharification potential in a plant, comprising overexpressing a polynucleotide encoding an acetyl xylan esterase polypeptide in at least one cell type in said plant. The invention further relates to methods for producing genetically modified plants overexpressing a polynucleotide encoding an acetyl xylan esterase polypeptide, as well as to genetically modified plants produced by such methods..
Swe Tree Technologies Ab
01/29/15
20150033409
 Expression cassettes for regulation of expression in monocotyledonous plants patent thumbnailnew patent Expression cassettes for regulation of expression in monocotyledonous plants
The present invention relates to expression cassettes comprising at least one transcription regulating nucleotide sequence obtainable from the group of genes of monocotyledonous plants consisting of caffeoyl-coa-o-methyltransferase genes, c8,7-sterol isomerase genes, hydroxyproline-rich glycoprotein (hrgp) genes, lactate dehydrogenase genes, and chloroplast protein 12 like genes. More preferably the transcription regulating sequences are obtainable from zea mays or oryza sativa.
Basf Plant Science Gmbh
01/29/15
20150033407
 Regulatory polynucleotides and uses thereof patent thumbnailnew patent Regulatory polynucleotides and uses thereof
The present disclosure provides compositions and methods for regulating expression of transcribable polynucleotides in plant cells, plant tissues, and plants. Compositions include regulatory polynucleotide molecules capable of providing expression in plant tissues and plants.
Monsanto Technology Llc
01/29/15
20150032385
 Methods of analyzing massively parallel sequencing data patent thumbnailnew patent Methods of analyzing massively parallel sequencing data
In at least one illustrative embodiment, a method may comprise selecting a first plurality of text strings that each represent a nucleotide sequence that was read by a massively parallel sequencing instrument, where the nucleotide sequences represented by the selected first plurality of text strings each correspond to a first target locus, comparing the selected first plurality of text strings to one another to determine an abundance count for each unique text string included in the selected first plurality of text strings, identifying a first number of unique text strings included in the selected first plurality of text strings as representing noise responses, and determining a method detection limit as a function of the abundance counts for the first number of unique text strings identified as representing noise responses.. .
Battelle Memorial Institute
01/29/15
20150032381
 Allelotyping methods for massively parallel sequencing patent thumbnailnew patent Allelotyping methods for massively parallel sequencing
In one illustrative embodiment, an allelotyping method may include selecting a plurality of text strings that each represent a nucleotide sequence that was read by a massively parallel sequencing (mps) instrument, where the nucleotide sequences represented by the selected plurality of text strings each correspond to a particular locus, comparing the selected plurality of text strings to one another to determine an abundance count for each unique text string included in the selected plurality of text strings, and determining one or more alleles for the particular locus by comparing the abundance count for each unique text string included in the selected plurality of text strings to an abundance threshold.. .
Battelle Memorial Institute
01/29/15
20150031868
 Diterpene production patent thumbnailnew patent Diterpene production
The present invention relates to a recombinant microorganism comprising one or more nucleotide sequence(s) encoding: a polypeptide having ent-copalyl pyrophosphate synthase activity; a polypeptide having ent-kaurene synthase activity; a polypeptide having ent-kaurene oxidase activity; and a polypeptide having kaurenoic acid 13-hydroxylase activity, whereby expression of the nucleotide sequence(s) confer(s) on the microorganism the ability to produce at least steviol. The recombinant microorganism may also be capable of expressing one or more udp-glucosyltransferases such that the microorganism is capable of producing one or more steviol glycosides..
Dsm Ip Assets B.v.
01/29/15
20150031777
 Mirna fingerprint in the diagnosis of wilms' tumour patent thumbnailnew patent Mirna fingerprint in the diagnosis of wilms' tumour
Micrornas (mirna) are a recently discovered class of small non-coding rnas (17-14 nucleotides). Due to their function as regulators of gene expression they play a critical role both in physiological and in pathological processes, such as cancer.
Comprehensive Biomarker Center Gmbh
01/29/15
20150031756
 Lentiviral vectors and uses thereof patent thumbnailnew patent Lentiviral vectors and uses thereof
The invention relates to compositions containing polynucleotide vectors capable of expressing a nucleic acid encoding a fusion polypeptide on the surface of a viral particle and/or a eukaryotic cell.. .
Dana-farber Cancer Institute
01/29/15
20150031755
 Nucleic acids specifically binding cgrp patent thumbnailnew patent Nucleic acids specifically binding cgrp
The present invention is related to a nucleic acid molecule capable of binding to cgrp, wherein the nucleic acid molecule comprises a central stretch of nucleotides, wherein the central stretch of nucleotides comprises a nucleotide sequence of 5′ hwn1n2yggan3an4umn5n6yn7n8n9n10n11kn12rn13adn14n15 arn16un17cn18n19un20n21 3′ [seq id no: 99], wherein h, w, y, g, a, u, m, b, k, r, d, c are ribonucleotides, and n1 is r or dg, n2 is u or dt, n3 is k or dg, n4 is c or dc, n5 is m or dc, n6 is b or du, n7 is n or dg, n8 is y or dt, n9 is n or dc, n10 is r or dg, n11 is v or da, n12 is k or dt or du, n13 is g or dg, n14 is a or da, n15 is u or dt, n16 is r or dg, n17 is y or dc, n18 is c or dc, n19 is b or dc, n20 is c or dc, n21 is c or dc, and dg, dt, dc, da and du are 2′-deoxyribonucleotides.. .
Noxxon Pharma Ag
01/29/15
20150031750
new patent

Treatment of brain derived neurotrophic factor (bdnf) related diseases by inhibition of natural antisense transcript to bdnf


The present invention relates to antisense oligonucleotides that modulate the expression of and/or function of brain derived neurotrophic factor (bdnf), in particular, by targeting natural antisense polynucleotides of brain derived neurotrophic factor (bdnf). The invention also relates to the identification of these antisense oligonucleotides and their use in treating diseases and disorders associated with the expression of bdnf..
Curna, Inc.
01/29/15
20150031743
new patent

Cell transfecting formulations of small interfering rna, related compositions and methods of making and use


Compositions incorporating small interfering ribonucleic acid (sirna) and certain lipid-conjugated polyamide compound-based delivery vehicles that are particularly useful in the delivery sirna and other polynucleotides to cells. Also, methods of making and using the compositions..
Novartis Vaccines And Diagnostics, Inc.
01/29/15
20150031622
new patent

Rhogef12 is a therapeutic target for the treatment of heart failure


The present invention relates to an inhibitor of the rho guanine nucleotide exchange factor 12 (rhogef12) or an inhibitor of an activator of rhogef12 for use in the prevention and/or treatment of heart failure associated with cardiac hypertrophy and/or cardiac fibrosis and diseases associated therewith. Further, it relates also a method of treatment and methods for identifying inhibitors of rho guanine nucleotide exchange factor 12 (rhogef12) or inhibitors of an activator of rhogef12..
Max-planck-gesellschaft Zur FÖrderung Der Wissenschaften E.v.
01/29/15
20150031607
new patent

Water-soluble aie luminogens for monitoring and retardation of fibrillation of amyloid proteins


Compounds that exhibit aggregation induced emission (aie), and more particularly to water-soluble conjugated polyene compounds that exhibit aggregation induced emission. The conjugated polyene compounds can be used as bioprobes for dna detection, g-quadruplex identification, and potassium-ion sensing.
The Hong Kong University Of Science And Technology
01/29/15
20150031601
new patent

Antimicrobial peptide variants and polynucleotides encoding same


The present invention relates to variants of a parent antimicrobial peptide. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants..
Addenium Biotech Aps
01/29/15
20150031584
new patent

Reverse transcription primers and methods of design


The present invention provides novel algorithms for designing oligonucleotides that do not substantially hybridize to a small group of unwanted transcripts, while hybridizing to most other transcripts. Such oligonucleotides are particularly useful as primers for reverse transcription.
Applied Biosystems, Llc
01/29/15
20150031580
new patent

Method for the quantitative assessment of global and specific dna repair capacities of at least one biological medium, and the applications therefor


A method for quantitative assessment of base excision repair (ber) and nucleotide excision repair (ner) dna repair capacities of at least one cellular extract, which method entails: a) preparing a range of plasmids with at least one physical or chemical treatment or both and recovering a supercoiled fraction of each of said plasmids, b) characterizing the lesions present on each of the plasmids of the range of plasmids; c) depositing the plasmids of the range of plasmids, and at least one supercoiled control plasmid without lesions onto a single solid support, according to a pre-established configuration a, so as to form a functionalized support divided into different zones a1 to ax, corresponding to an integer equal to the number of cellular extracts to be simultaneously tested, each zone containing supercoiled plasmids treated with at least one physical or chemical treatment that induces a lesion acted upon by ber mechanisms, and at least one other zone containing supercoiled plasmids treated with at least one physical or chemical treatment that induces a lesion acted upon by ner mechanisms; d) incubating the functionalized support obtained in step c) with various repair solutions, each of which contains at least one cellular extract from a subject, and labeled nucleotide phosphates; e) washing the functionalized support at least once; f) directly or indirectly measuring the signal produced by the labeled nucleotide triphosphate incorporated into the dna during the repair reaction in step d), in each of the different and pre-established zones a1 to ax; g) recording and quantifying the signal corresponding to each deposit of plasmid in each zone a1 to ax; and h) determining the ratio of the signals of the plasmids containing the lesions relative to the control plasmid jointly deposited.. .
Commissariat A L'energie Atomique
01/29/15
20150031571
new patent

Chemiluminescent nanoparticles and uses thereof


Gold nanoparticles having luminol covalently linked thereto and optionally functionalized with an oligonucleotide and bacterial or viral detection assays. In one aspect, the detection system for detecting an analyte in a sample comprises a light-shielding container having a fiberoptic cable for transmitting light generated within the light-shielding container to a photodetector; a plurality of functionalized nanoparticles deposited in solid form on or within a support, such that the support is located within the light-shielding container; wherein the functionalized nanoparticles comprise nanoparticles covalently attached to one or more chemiluminescent moieties; and a reagent system which causes the chemiluminescent moieties to produce light in the presence of the reagent system and the analyte in the sample..
Kansas State University Research Foundation
01/29/15
20150031565
new patent

Determination of the identities of single nucleotide polymorphisms, point mutations and characteristic nucleotides in dna


A method of genotyping single nucleotide polymorphisms (“snp”) and point mutations in nucleic acid based on chain extension by polymerase. This invention is based on the fact that the neighboring sequence immediately 3′ adjacent to the site is known, and the nucleoside immediately 5′ adjacent to any snp/point mutation site is also known.
01/29/15
20150031560
new patent

Sequencing by orthogonal synthesis


A method for sequencing includes steps of (a) providing first and second nucleic acid templates, wherein the two templates have different sequences; (b) extending a first primer bound to the first template using a first polymerase species and a first set of nucleotide analogs; (c) extending a second primer bound to the second template using a second polymerase species and a second set of nucleotide analogs, wherein the first polymerase species is different from the second polymerase species and wherein the first set of nucleotide analog is different from the second set of nucleotide analog, (d) detecting the first and second primer extension products; and (e) repeating steps (b) through (d), thereby determining the different sequences of the first and second templates.. .
Illumina, Inc.
01/29/15
20150031559
new patent

Increased confidence of allele calls with molecular counting


Aspects of the present invention include methods and compositions for determining the number of individual polynucleotide molecules originating from the same genomic region of the same original sample that have been sequenced in a particular sequence analysis configuration or process. In these aspects of the invention, a degenerate base region (dbr) is attached to the starting polynucleotide molecules that are subsequently sequenced (e.g., after certain process steps are performed, e.g., amplification and/or enrichment).
Population Genetics Technologies Ltd
01/29/15
20150031551
new patent

Control nucleic acid sequences for use in sequencing-by-synthesis and methods for designing the same


A method for nucleic acid sequencing includes (a) disposing a plurality of template polynucleotide strands in a plurality of defined spaces disposed on a sensor array, at least some of the template polynucleotide strands comprising a test or control sequence; (b) exposing a plurality of the template polynucleotide strands in the defined spaces to a series of flows of nucleotide species flowed according to a predetermined ordering; and (c) determining sequence information for a plurality of the template polynucleotide strands in the defined spaces based on the flows of nucleotide species to generate a plurality of sequencing reads corresponding to the template polynucleotide strands, wherein the test or control sequence comprises a sequence determined by identifying, using a variant caller, loci with systematic errors present in a plurality of sequencing runs included in a training set of sequencing runs.. .
Life Technologies Corporation
01/29/15
20150031130
new patent

Compounds and methods for enhanced cellular uptake


Described herein are conjugated modified oligonucleotides that are complementary to a target rna. The conjugate facilitates cellular uptake of the modified oligonucleotide, resulting improved potency..
Regulus Therapeutics Inc.
01/29/15
20150031128
new patent

Culture medium for eukaryotic cells


The invention pertains to the use of (i) one or more c2-c6 alpha-hydroxy acids, salts of these acids, esters of these acids and combinations thereof; and (ii) one or more compounds selected from—the group of amino acid derivatives consisting of γ-glutamyl amino acids, pyroglutamyl amino acids, glutamate-containing or proline-containing dipeptides, oxo-aminoacids, homo-amino acids, n-acetyl amino-acids and glycyl-glycine; -phenolic acid derivatives; -linear c2-c6 or cyclic c6 sugar alcohols; -pyridinic acid derivatives; and -nucleobases and/or nucleotides chosen from uracil, adenine, adenosine 3′-monophosphate (3′-amp) and adenosine 5′-monophosphate (amp), as a growth-and production promoting ingredient, in culture media for culturing eukaryotic cells. The invention further pertains to culture media containing these components at levels of at least 0.001 mg/l..
Friesland Brands B.v.
01/29/15
20150031116
new patent

Integrated active flux microfluidic devices and methods


The invention relates to a microfabricated device for the rapid detection of dna, proteins or other molecules associated with a particular disease. The devices and methods of the invention can be used for the simultaneous diagnosis of multiple diseases by detecting molecules (e.g.
California Institute Of Technology
01/29/15
20150031113
new patent

Polypeptides having endoglucanase activity and polynucleotides encoding same


Provided are isolated polypeptides having endoglucanase activity, catalytic domains, cellulose binding domains and polynucleotides encoding the polypeptides, catalytic domains or cellulose binding domains. Also provided are nucleic acid constructs, vectors and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides catalytic domains or cellulose binding domains..
Novozymes A/s
01/29/15
20150031111
new patent

Lipase variants and polynucleotides encoding same


The present invention relates to isolated lipase variants, comprising a substitution at one or more positions corresponding to positions i86d,e,n,q, e87c, i90d,e,q, and n92d,e,q of the mature polypeptide of seq id no: 2, wherein the variant has lipase activity. In some embodiments the present invention relates to isolated polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; methods of producing the variants; and compositions comprising the variants.
Novozymes A/s
01/29/15
20150031095
new patent

Enone reductases


The disclosure relates to engineered enone reductase polypeptides having improved properties, polynucleotides encoding the engineered polypeptides, related vectors, host cells, and methods for making the engineered enone reductase polypeptides. The disclosure also provides methods of using the engineered enone reductase polypeptides for chemical transformations..
Codexis, Inc.
01/29/15
20150031094
new patent

Polynucleotides encoding engineered ketoreductase polypeptides


The present disclosure provides engineered ketoreductase enzymes having improved properties as compared to a naturally occurring wild-type ketoreductase enzyme. Also provided are polynucleotides encoding the engineered ketoreductase enzymes, host cells capable of expressing the engineered ketoreductase enzymes, and methods of using the engineered ketoreductase enzymes to synthesize a variety of chiral compounds.
Codexis, Inc.
01/29/15
20150031091
new patent

Polypeptides having alpha-amylase activity and polynucleotides encoding same


The present invention provides isolated polypeptides having alpha-amylase activity catalytic domains, carbohydrate binding domains and polynucleotide encoding the polypeptides, catalytic domains or carbohydrate binding domains. The invention also provides nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides, catalytic domains or carbohydrate binding domains..
Novozymes A/s
01/29/15
20150031088
new patent

Gene synthesis process, gene chip and kit


Provided is a chip process of gene synthesis, and the process comprises incorporating the whole procedure, which comprises amplifying oligonucleotides and assembling the oligonucleotides into a gene in parallel, onto a single chip. A specific mismatch endonuclease is also used in the process to establish an error repair system in gene synthesis, and the error rate is decreased to about 0.19 mismatched bases/kb.
01/29/15
20150031082
new patent

Polypeptides having beta-glucosidase activity, beta-xylosidase activity, or beta-glucosidase activity and beta-xylosidase activity and polynucleotides encoding same


The present invention relates to isolated polypeptides having beta-glucosidase activity, beta-xylosidase activity, or beta-glucosidase and beta-xylosidase activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides..
Novozymes A/s
01/29/15
20150031080
new patent

Cellobiohydrolase variants and polynucleotides encoding same


The present invention relates to variants of a parent cellobiohydrolase ii. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants..
Novozymes, Inc.
01/29/15
20150031079
new patent

Polypeptides having xylanase activity and polynucleotides encoding same


The present invention relates to isolated polypeptides having xylanase activity and polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides..
Novozymes Inc.
01/29/15
20150031060
new patent

Fad-conjugated glucose dehydrogenase gene


Disclosed herein are a gene (polynucleotide) encoding an fad-conjugated glucose dehydrogenase which can be characterized by reactivity to glucose, thermal stability, substrate-recognition performance, and low activity for maltose; a process for the production of the enzyme using a transformant cell transfected with the gene; a method for the determination of glucose; a reagent composition for use in the determination of glucose; and a biosensor for use in the determination of glucose. An embodiment is a polynucleotide encoding an fad-conjugated glucose dehydrogenase, comprising a polypeptide whose amino acid sequence comprises x1-x2-x3-x4-x5-x6, wherein x1 and x2 independently represent an aliphatic amino acid residue; x3 and x6 independently represent a branched amino acid residue; and x4 and x5 independently represent a heterocyclic amino acid residue or an aromatic amino acid residue..
Ikeda Food Research Co., Ltd.
01/29/15
20150031034
new patent

Methods and compositions for detecting genetic material


This invention provides compositions and methods for detecting differences in copy number of a target polynucleotide. In some cases, the methods and compositions provided herein are useful for diagnosis of fetal genetic abnormalities, when the starting sample is maternal tissue (e.g., blood, plasma).
Bio-rad Laboratories, Inc.
01/29/15
20150031024
new patent

Enzymatic preparation of 10 base to 50 kb double-strand dna reagent for sequencing with a nanopore-polymerase sequencing device


The invention herein disclosed provides for devices, reagents, and methods that can detect and control an individual polymer in a mixture is acted upon by another compound, for example, an enzyme, in a nanopore. Of particular note is the use of reagents to rapidly sequence a polynucleotide.
The Regents Of The University Of California
01/29/15
20150031020
new patent

Enzyme-pore constructs


The invention relates to constructs comprising a transmembrane protein pore subunit and a nucleic acid handling enzyme. The pore subunit is covalently attached to the enzyme such that both the subunit and enzyme retain their activity.
Oxford Nanopore Technologies Limited
01/29/15
20150031015
new patent

Identification of poliovirus strains


The present invention relates to methods for identifying and/or distinguishing polioviral strains, in particular polioviral strains used in vaccine production. The methods are based on selective hybridisation with oligonucleotides, i.e.
En Sport
01/29/15
20150030621
new patent

Baculovirus-based vaccines


The present invention relates to a recombinant baculovirus comprising: (a) a nucleotide sequence encoding a foreign virus envelope protein; (b) a first promoter operatively linked to the envelope-encoding nucleotide sequence; (c) a nucleotide sequence encoding an antigen protein; and (d) a second promoter operatively linked to the antigen-encoding nucleotide sequence; and a vaccine composition using the same. The recombinant baculovirus of the present invention has an excellent efficacy on both humoral and cellular immune responses against a specific antigen (e.g., hpv l1), enabling to function as a more efficient dna vaccine..
Kr Biotech Co., Ltd.
01/29/15
20150030620
new patent

Packaging of immunostimulatory substances into virus-like particles: preparation and use


The invention relates to the finding that virus like particles (vlps) can be loaded with immunostimulatory substances, in particular with dna oligonucleotides containing non-methylated c and g (cpgs). Such cpg-vlps are dramatically more immunogenic than their cpg-free counterparts and induce enhanced b and t cell responses.
Cytos Biotechnology Ag
01/29/15
20150030605
new patent

Polypeptides and polynucleotides for artemin and related ligands, and methods of use thereof


The invention encompasses polypeptides, polynucleotides, and antibodies, for artemin and related ligands, including persephin (pspn). The invention also encompasses expression vectors and host cells for producing these polypeptides, polynucleotides, or antibodies.
Auckland Uniservices Limited
01/29/15
20150030586
new patent

Compositions and methods for the therapy and diagnosis of cancer


Compositions and methods for the therapy and diagnosis of cancer are disclosed. For example, illustrative compositions comprise one or more cancer-associated antibodies, polypeptides, polynucleotides, antigen presenting cells, and the like.


Popular terms: [SEARCH]



Follow us on Twitter
twitter icon@FreshPatents

###

This listing is a sample listing of patent applications related to Nucleotide for is only meant as a recent sample of applications filed, not a comprehensive history. There may be associated servicemarks and trademarks related to these patents. Please check with patent attorney if you need further assistance or plan to use for business purposes. This patent data is also published to the public by the USPTO and available for free on their website. Note that there may be alternative spellings for Nucleotide with additional patents listed. Browse our RSS directory or Search for other possible listings.
     SHARE
  
         





0.2556

3714

71 - 0 - 77